CRIS Current Research Information System

MINARINI, ANNA
 Distribuzione geografica
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Continente #
EU - Europa 8.596
NA - Nord America 8.423
AS - Asia 6.611
AF - Africa 620
SA - Sud America 318
Continente sconosciuto - Info sul continente non disponibili 19
OC - Oceania 11
Totale 24.598
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Nazione #
US - Stati Uniti d'America 8.312
IT - Italia 4.049
CN - Cina 1.904
SG - Singapore 1.843
VN - Vietnam 1.348
GB - Regno Unito 1.341
DE - Germania 645
HK - Hong Kong 509
SE - Svezia 507
FR - Francia 410
UA - Ucraina 362
IN - India 333
RU - Federazione Russa 307
NL - Olanda 217
CI - Costa d'Avorio 214
BR - Brasile 201
IE - Irlanda 195
TG - Togo 160
ZA - Sudafrica 132
JP - Giappone 127
BD - Bangladesh 111
EE - Estonia 94
KR - Corea 94
FI - Finlandia 86
CA - Canada 67
BG - Bulgaria 61
SC - Seychelles 49
JO - Giordania 48
AR - Argentina 43
CH - Svizzera 43
ES - Italia 43
PH - Filippine 40
BE - Belgio 38
ID - Indonesia 38
TH - Thailandia 36
MX - Messico 33
PL - Polonia 30
TR - Turchia 28
TW - Taiwan 27
IQ - Iraq 26
HR - Croazia 25
EC - Ecuador 24
GR - Grecia 23
PK - Pakistan 22
AT - Austria 20
EU - Europa 17
CZ - Repubblica Ceca 15
LT - Lituania 15
CO - Colombia 14
IR - Iran 14
CL - Cile 13
LU - Lussemburgo 13
RO - Romania 13
MA - Marocco 11
SA - Arabia Saudita 10
AU - Australia 9
LB - Libano 9
UZ - Uzbekistan 9
AL - Albania 8
EG - Egitto 8
MY - Malesia 8
NG - Nigeria 8
TN - Tunisia 8
ET - Etiopia 7
PE - Perù 7
PY - Paraguay 7
AZ - Azerbaigian 5
IL - Israele 5
KE - Kenya 5
PT - Portogallo 5
SK - Slovacchia (Repubblica Slovacca) 5
MT - Malta 4
NP - Nepal 4
VE - Venezuela 4
DO - Repubblica Dominicana 3
DZ - Algeria 3
GT - Guatemala 3
HU - Ungheria 3
LV - Lettonia 3
LY - Libia 3
NO - Norvegia 3
AE - Emirati Arabi Uniti 2
BO - Bolivia 2
BY - Bielorussia 2
CR - Costa Rica 2
DK - Danimarca 2
GH - Ghana 2
KZ - Kazakistan 2
LK - Sri Lanka 2
MD - Moldavia 2
MU - Mauritius 2
NZ - Nuova Zelanda 2
OM - Oman 2
RS - Serbia 2
SM - San Marino 2
UY - Uruguay 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AG - Antigua e Barbuda 1
AO - Angola 1
BH - Bahrain 1
Totale 24.580
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Città #
Singapore 1.243
Southend 1.152
Ashburn 800
Fairfield 725
San Jose 546
Chandler 493
Hong Kong 493
Santa Clara 460
Bologna 385
Woodbridge 356
Houston 352
Ho Chi Minh City 338
Wilmington 318
Seattle 307
Hanoi 286
Princeton 272
Ann Arbor 265
Beijing 246
Cambridge 244
Jacksonville 239
Milan 236
Abidjan 214
Rome 214
Hefei 211
Dublin 191
Boardman 186
Lomé 160
Los Angeles 149
Padova 149
Dallas 136
Council Bluffs 132
Lauterbourg 121
Nanjing 121
New York 121
Westminster 121
Tokyo 105
Dong Ket 101
Berlin 78
Buffalo 74
Jinan 74
Florence 70
Naples 68
Seoul 66
Helsinki 65
Shenyang 63
Turin 62
Saint Petersburg 61
Sofia 61
Haiphong 60
Palermo 59
Guangzhou 55
Medford 54
Hebei 53
Bari 52
Changsha 51
Redmond 51
Redwood City 51
Amman 48
Da Nang 44
Munich 44
Catania 41
Mülheim 41
Redondo Beach 41
San Diego 40
Shanghai 39
Nanchang 38
Verona 36
Zhengzhou 36
Tianjin 35
Brussels 34
Genoa 32
Falls Church 31
Hangzhou 30
Yubileyny 30
Frankfurt am Main 29
Johannesburg 29
Mahé 29
Parma 29
Phoenix 28
Chicago 27
Dearborn 25
Reggio Emilia 25
Orem 24
Benevento 23
Jiaxing 23
São Paulo 23
Norwalk 22
Des Moines 21
Haikou 21
Montreal 21
Rimini 21
San Francisco 21
Atlanta 20
Bengaluru 20
Modena 20
Jakarta 19
London 19
Taiyuan 19
Toronto 19
Warsaw 19
Totale 14.652
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Nome #
Farmaci che agiscono sul sistema renina-angiotensina 1.709
Trasportatori di membrana dei farmaci 892
Antidepressivi e antipsicotici 774
Benextramine and derivatives as novel human monoamine oxidases inhibitors: an integrated approach 271
Galantamine-memantine hybrids for Alzheimer's disease: The influence of linker rigidity in biological activity and pharmacokinetic properties 270
Novel Polyamine–Naphthalene Diimide Conjugates Targeting Histone Deacetylases and DNA for Cancer Phenotype Reprogramming 256
Progettazione e sintesi di analoghi rigidi di metoctramina nello studio dei recettori muscarinici 239
Bovine Serum Amine Oxidase and Polyamine Analogues: Chemical Synthesis and Biological Evaluation Integrated with Molecular Docking and 3-D QSAR Studies 233
Cytotoxicity of methoctramine and methoctramine-related polyamines. 231
Merging memantine and ferulic acid to probe connections between NMDA receptors, oxidative stress and amyloid-β peptide in Alzheimer's disease 229
Progettazione e sintesi di poliammine a potenziale attività antitumorale 228
Structure-activity relationships of acetylcholinesterase noncovalent inhibitors based on a polyamine backbone. 3. Effect of replacing the inner polymethylene chain with cyclic moieties 224
DESIGN, SYNTHESIS AND BIOLOGICAL EVALUATION OF SUSTITUTED NAPHTHALENE IMIDES AND DIIMIDES AS ANTICANCER AGENT 224
Rational Approach to discover multipotent anti-Alzheimer drugs 217
Nature-Inspired Multifunctional Ligands: Focusing on Amyloid-Based Molecular Mechanisms of Alzheimer’s Disease 217
Polyamine conjugation of curcumin analogues toward the discovery of mitochondria-directed neuroprotective agents. 208
Design, synthesis, and biological evaluation of conformationally restricted rivastigmine analogues 206
Cystamine-tacrine dimer: A new multi-target-directed ligand as potential therapeutic agent for Alzheimer's disease treatment. 206
Pharmacophore Hybridization To Discover Novel Topoisomerase II Poisons with Promising Antiproliferative Activity 206
Exploring the activity of polyamine analogues on polyamine and spermine oxidase: methoctramine, a potent and selective inhibitor of polyamine oxidase 205
Progettazione e sintesi di derivati poliamminici per il trattamento della malattia di Alzheimer 202
Design and synthesis of new multitarget agents for the study of neuroinflammation in Alzheimer's disease 199
Alzheimer's disease: new approaches to drug discovery. 198
Multitargeted drugs discovery: Balancing anti-amyloid and anticholinesterase capacity in a single chemical entity 194
Structure-activity relationships of novel substituted naphthalene diimides as anticancer agents 194
Novel, Potent, and Druglike Tetrahydroquinazoline Inhibitor That Is Highly Selective for Human Topoisomerase II α over β 184
Memantine Derivatives as Multitarget Agents in Alzheimer’s Disease 183
Lights and shadows of electrophile signaling: Focus on the Nrf2-Keap1 pathway 182
Novel polyamine-based Histone deacetylases-Lysine demethylase 1 dual binding inhibitors 182
In vivo characterization of ARN14140, a memantine/galantamine-based multi-target compound for Alzheimer's disease 182
Natural polyamines and synthetic analogs modify the growth and the morphology of Pyrus communis pollen tubes affecting ROS levels and causing cell death 182
Double Attack to Oxidative Stress in Neurodegenerative Disorders: MAO-B and Nrf2 as Elected Targets 181
Inhibition of β-Amyloid Aggregation in Alzheimer's Disease: The Key Role of (Pro)electrophilic Warheads 181
LC determination of leuprolide component amino acids in injectable solution by phanquinone pre-column derivatization labelling procedure 180
Study of the cytotoxic effects of the new synthetic isothiocyanate CM9 and its fullerene derivative on human T-leukemia cells 180
Design, Synthesis, and biological evaluation of naphtalene diimides derivatives as anticancer agent 178
Polyamine Conjugation as a Promising Strategy To Target Amyloid Aggregation in the Framework of Alzheimer’s Disease 176
Process for preparation of 1,4-benzoquinone-2,5-diamines by reaction of amines with 1,4-benzoquinones bearing leaving groups at the 2- and 5-positions 175
Synthetic polyamines activating autophagy: Effects on cancer cell death 173
Design, synthesis, and biological evaluation of pirenzepine analogs bearing a 1,2-cyclohexanediamine and a perhydroquinoxaline units in exchange for the piperazine ring as antimuscarinics 170
Macrocyclic naphthalene diimides as G-quadruplex binders 170
Design, synthesis, and biological evaluation of substituted naphtalene imides and diimides as anticancer agents 167
Multitarget-directed ligands: Innovative chemical probes and therapeutic tools against Alzheimer's disease 166
Exploiting RNA as a new biomolecular target for synthetic polyamines 165
Inhibition of Acetylcholinesterase, Beta-Amyloid Aggregation, and NMDA Receptors in Alzheimer's Disease: A Promising Direction for the Multi-target-Directed Ligands Gold Rush 163
Preparation, characterization and in vitro evaluation of sterically stabilized liposome containing a naphthalenediimide derivative as anticancer agent 162
Novel Class of Quinone-Bearing Polyamines as Multi-Target-Directed Ligands To Combat Alzheimer's Disease 161
Exploring the effects of isothiocyanates on chemotherapeutic drugs 160
Lipocrine, a multipotent drug for the investigation of Alzheimer's disease 159
Synthesis of Monomeric Derivatives To Probe Memoquin's Bivalent Interactions 159
Analysis of the muscarinic receptor subtype mediating inhibition of the neurogenic contractions in rabbit isolated vas deferens by a series of polymethylene tetra-amines 157
Progress in acetylcholinesterase inhibitors for Alzheimer's disease: an update 157
An optimized polyamine moiety boosts the potency of human type II topoisomerase poisons as quantified by comparative analysis centered on the clinical candidate F14512 155
Combined inhibition of the EGFR/AKT pathways by a novel conjugate of quinazoline with isothiocyanate. 155
New quinazoline compounds as non-peptidomimetic BACE-1 inhibitors in the treatment of Alzheimer's disease 154
Polyamine-containing etoposide derivatives as poisons of human type II topoisomerases: Differential effects on topoisomerase IIα and IIβ 154
Cystamine-tacrine dimer: a new multi-target-directed ligand as potential therapeutic agent for Alzheimer’s disease treatment 153
Beta-secretase monolithic micro-IMER (immobilized enzyme reactor) for on-line HPLC screening of quinone-bearing polyamine inhibitors. 152
Multifunctional Tacrine Derivatives in Alzheimer’s Disease 152
Oxidative stress in Alzheimer’s disease: are we connecting the dots? 152
Multi-target Design Strategies in the Context of Alzheimer's Disease: Acetylcholinesterase Inhibition and NMDA Receptor Antagonism as the Driving Forces 152
Exploration of the Neuromodulatory Properties of Fyn and GSK-3β Kinases Exploiting 7-Azaindole-Based Inhibitors 151
One-molecule-multiple-target strategy: a novel multifunctional molecule designed to block EGF-r and to exert pro-apoptotic effects 151
Polyamine–Drug Conjugates: Do They Boost Drug Activity? 150
Preliminary evaluation of the cytotoxicity of naphthalene diimide-polyamine conjugates in human cancer cells 150
Cytotoxicity of Methoctramine and related Spermine analogues 149
Multi-target-Directed Ligands To Combat Neurodegenerative Diseases 149
Heterocyclic inhibitors of AChE acylation and peripheral sites. 148
Novel targets for “old” polyamine analogues: monoamine oxidases and benextramine derivatives 147
Structure-activity relationships of methoctramine-related polyamines as muscarinic antagonist: Effect of replacing the inner polymethylene chain with cyclic moieties 146
Progress in acetylcholinesterase inhibitors for Alzheimer's disease 143
MTDL design strategy in the context of Alzheimer's disease: from lipocrine to memoquin and beyond 143
In vitro and in vivo evaluation of polymethylene tetraamine derivatives as NMDA receptor channel blockers 143
Structure-Activity Relationships of Acetylcholinesterase Noncovalent Inhibitors Based on a Polyamine Backbone. 4. Futher Investigation on the Inner Spacer. 142
null 141
Distinct biological responses of metastatic castration resistant prostate cancer cells upon exposure to G-quadruplex interacting naphthalenediimide derivatives 141
Multi-Target-Direcetd Ligands as acetylcholinesterase inhibitors and nicotinic modulators for Alzheimer's disease 140
Benextramine derivatives as probes to target human monoamine oxidases 140
Polymethylene tetraamine backbone as template for the development of biologically active polyamines 139
Discovery of Memoquin, a Multitarget-Directed Ligand (MTDL) for the Treatment of Alzheimer’s Disease 139
Synthetic polyamines as potential amine oxidase inhibitors: a preliminary study. 138
Cytotoxicity of methoctramine-related polyamines 137
Methoctramine-related polyamines as antinociceptive agents 136
Polyamines may modulate both G protein-coupled receptors and G proteins 136
Natural-product-inspired modulators of Alzheimer’s disease: focus on amyloid and oxidative stress 136
Novel polyamine analogues: from substrates towards potential inhibitors of monoamine oxidases 136
Structure-Activity Relationships of New Acetylcholinesterase Noncovalent Inhibitors Based on a Polyamine Backbone 135
Methoctramine analogues inhibit responses to capsaicin and protons in rat dorsal root ganglion neurons 135
Methoctramine analogues inhibit responses to capsaicin in DRG neurons and cloned TRPV1 132
From dual binding site acetylcholinesterase inhibitors to multi-target-directed ligands (MTDLs): a step forward in the treatment of Alzheimer's disease 132
Ottimizzazione del lead: metodi tradizionali 132
Naphthalene diimide-polyamine hybrids as antiproliferative agents: Focus on the architecture of the polyamine chains 132
Recent advances in alpha1-adrenoreceptor antagonists as pharmacological tools and therapeutic agents. 131
Role of Fyn Kinase Inhibitors in Switching Neuroinflammatory Pathways 131
Inibitori delle fosfodiesterasi 130
Polyamines in Drug Discovery: From the Universal Template Approach to the Multitarget-Directed Ligand Design Strategy 130
Discovery of multipotent drugs for the teratment of Alzheimer's disease 129
Rational design of multitarget-directed antioxidants: merging memoquin and lipocrine molecular frameworks 128
Multi-Target-Directed Drug Design Strategy: Development of new Naphthalene Diimides Bearing Isothiocyanate Functionality As Anticancer Agents 127
From Monoamine Oxidase Inhibition to Antiproliferative Activity: New Biological Perspectives for Polyamine Analogs 127
Totale 19.648
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Categoria #
all - tutte 66.575
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 4.387
Totale 70.962
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021264 0 0 0 0 0 0 0 0 0 0 0 264
2021/20222.626 144 92 163 190 249 180 99 201 141 263 481 423
2022/20232.609 277 321 123 297 150 174 179 148 475 72 233 160
2023/20241.675 70 161 113 122 126 286 95 141 120 126 135 180
2024/20253.828 280 510 398 308 710 224 250 153 98 186 165 546
2025/20267.445 423 640 739 519 870 415 799 277 1.485 565 418 295
Totale 25.057