CRIS Current Research Information System

MINARINI, ANNA
 Distribuzione geografica
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Continente #
NA - Nord America 8.730
EU - Europa 8.700
AS - Asia 6.703
AF - Africa 624
Continente sconosciuto - Info sul continente non disponibili 483
SA - Sud America 322
OC - Oceania 11
Totale 25.573
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Nazione #
US - Stati Uniti d'America 8.586
IT - Italia 4.137
CN - Cina 1.916
SG - Singapore 1.869
VN - Vietnam 1.354
GB - Regno Unito 1.343
DE - Germania 645
HK - Hong Kong 519
SE - Svezia 507
FR - Francia 411
UA - Ucraina 362
IN - India 339
RU - Federazione Russa 307
NL - Olanda 222
CI - Costa d'Avorio 214
BR - Brasile 202
IE - Irlanda 195
TG - Togo 160
BD - Bangladesh 141
ZA - Sudafrica 133
JP - Giappone 127
KR - Corea 95
EE - Estonia 94
FI - Finlandia 86
CA - Canada 77
BG - Bulgaria 61
SC - Seychelles 51
JO - Giordania 48
ES - Italia 47
AR - Argentina 43
CH - Svizzera 43
PH - Filippine 40
BE - Belgio 39
ID - Indonesia 39
MX - Messico 36
TH - Thailandia 36
PL - Polonia 32
TR - Turchia 28
TW - Taiwan 27
IQ - Iraq 26
HR - Croazia 25
EC - Ecuador 24
GR - Grecia 23
PK - Pakistan 22
AT - Austria 20
EU - Europa 17
CO - Colombia 15
CZ - Repubblica Ceca 15
LT - Lituania 15
IR - Iran 14
CL - Cile 13
LU - Lussemburgo 13
RO - Romania 13
MA - Marocco 11
SA - Arabia Saudita 10
AU - Australia 9
CR - Costa Rica 9
LB - Libano 9
UZ - Uzbekistan 9
AL - Albania 8
EG - Egitto 8
MY - Malesia 8
NG - Nigeria 8
TN - Tunisia 8
ET - Etiopia 7
PE - Perù 7
PY - Paraguay 7
SK - Slovacchia (Repubblica Slovacca) 6
VE - Venezuela 6
AZ - Azerbaigian 5
IL - Israele 5
KE - Kenya 5
PT - Portogallo 5
DZ - Algeria 4
MT - Malta 4
NP - Nepal 4
DO - Repubblica Dominicana 3
GT - Guatemala 3
HN - Honduras 3
HU - Ungheria 3
LV - Lettonia 3
LY - Libia 3
NO - Norvegia 3
PR - Porto Rico 3
AE - Emirati Arabi Uniti 2
BO - Bolivia 2
BY - Bielorussia 2
DK - Danimarca 2
GH - Ghana 2
JM - Giamaica 2
KZ - Kazakistan 2
LK - Sri Lanka 2
MD - Moldavia 2
MU - Mauritius 2
NI - Nicaragua 2
NZ - Nuova Zelanda 2
OM - Oman 2
RS - Serbia 2
SM - San Marino 2
TT - Trinidad e Tobago 2
Totale 25.084
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Città #
Singapore 1.267
Southend 1.152
Ashburn 816
Fairfield 725
San Jose 562
Hong Kong 502
Chandler 493
Santa Clara 477
Bologna 387
Woodbridge 356
Houston 353
Ho Chi Minh City 338
Wilmington 319
Seattle 307
Hanoi 286
Princeton 272
Ann Arbor 265
Beijing 250
Cambridge 244
Council Bluffs 240
Jacksonville 239
Milan 237
Rome 223
Abidjan 214
Hefei 211
Dublin 191
Boardman 186
Lomé 160
Los Angeles 154
Padova 149
Dallas 141
New York 124
Lauterbourg 121
Nanjing 121
Westminster 121
Tokyo 105
Dong Ket 101
Berlin 78
Buffalo 76
Naples 75
Jinan 74
Florence 72
Seoul 67
Helsinki 65
Turin 64
Shenyang 63
Saint Petersburg 61
Sofia 61
Haiphong 60
Palermo 59
Bari 56
Guangzhou 55
Medford 54
Hebei 53
Changsha 51
Redmond 51
Redwood City 51
Amman 48
Da Nang 44
Munich 44
Catania 41
Mülheim 41
Redondo Beach 41
San Diego 40
Shanghai 39
Nanchang 38
Verona 36
Zhengzhou 36
Genoa 35
Tianjin 35
Brussels 34
Falls Church 31
Chicago 30
Hangzhou 30
Parma 30
Phoenix 30
Yubileyny 30
Frankfurt am Main 29
Johannesburg 29
Mahé 29
Dearborn 26
Reggio Emilia 25
Orem 24
San Francisco 24
Benevento 23
Bengaluru 23
Jiaxing 23
São Paulo 23
Montreal 22
Norwalk 22
Rimini 22
Atlanta 21
Des Moines 21
Haikou 21
London 21
Warsaw 21
Modena 20
Jakarta 19
Taiyuan 19
Toronto 19
Totale 14.914
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Nome #
Farmaci che agiscono sul sistema renina-angiotensina 1.757
Trasportatori di membrana dei farmaci 914
Antidepressivi e antipsicotici 792
Benextramine and derivatives as novel human monoamine oxidases inhibitors: an integrated approach 273
Galantamine-memantine hybrids for Alzheimer's disease: The influence of linker rigidity in biological activity and pharmacokinetic properties 271
Novel Polyamine–Naphthalene Diimide Conjugates Targeting Histone Deacetylases and DNA for Cancer Phenotype Reprogramming 259
Progettazione e sintesi di analoghi rigidi di metoctramina nello studio dei recettori muscarinici 240
Bovine Serum Amine Oxidase and Polyamine Analogues: Chemical Synthesis and Biological Evaluation Integrated with Molecular Docking and 3-D QSAR Studies 236
Cytotoxicity of methoctramine and methoctramine-related polyamines. 235
Merging memantine and ferulic acid to probe connections between NMDA receptors, oxidative stress and amyloid-β peptide in Alzheimer's disease 234
Progettazione e sintesi di poliammine a potenziale attività antitumorale 231
DESIGN, SYNTHESIS AND BIOLOGICAL EVALUATION OF SUSTITUTED NAPHTHALENE IMIDES AND DIIMIDES AS ANTICANCER AGENT 230
Structure-activity relationships of acetylcholinesterase noncovalent inhibitors based on a polyamine backbone. 3. Effect of replacing the inner polymethylene chain with cyclic moieties 226
Rational Approach to discover multipotent anti-Alzheimer drugs 220
Nature-Inspired Multifunctional Ligands: Focusing on Amyloid-Based Molecular Mechanisms of Alzheimer’s Disease 220
Polyamine conjugation of curcumin analogues toward the discovery of mitochondria-directed neuroprotective agents. 210
Cystamine-tacrine dimer: A new multi-target-directed ligand as potential therapeutic agent for Alzheimer's disease treatment. 210
Design, synthesis, and biological evaluation of conformationally restricted rivastigmine analogues 209
Exploring the activity of polyamine analogues on polyamine and spermine oxidase: methoctramine, a potent and selective inhibitor of polyamine oxidase 208
Pharmacophore Hybridization To Discover Novel Topoisomerase II Poisons with Promising Antiproliferative Activity 208
Progettazione e sintesi di derivati poliamminici per il trattamento della malattia di Alzheimer 205
Design and synthesis of new multitarget agents for the study of neuroinflammation in Alzheimer's disease 203
Alzheimer's disease: new approaches to drug discovery. 200
Structure-activity relationships of novel substituted naphthalene diimides as anticancer agents 197
Multitargeted drugs discovery: Balancing anti-amyloid and anticholinesterase capacity in a single chemical entity 195
Novel, Potent, and Druglike Tetrahydroquinazoline Inhibitor That Is Highly Selective for Human Topoisomerase II α over β 189
Novel polyamine-based Histone deacetylases-Lysine demethylase 1 dual binding inhibitors 188
Lights and shadows of electrophile signaling: Focus on the Nrf2-Keap1 pathway 186
In vivo characterization of ARN14140, a memantine/galantamine-based multi-target compound for Alzheimer's disease 186
Double Attack to Oxidative Stress in Neurodegenerative Disorders: MAO-B and Nrf2 as Elected Targets 184
Inhibition of β-Amyloid Aggregation in Alzheimer's Disease: The Key Role of (Pro)electrophilic Warheads 184
Memantine Derivatives as Multitarget Agents in Alzheimer’s Disease 184
Natural polyamines and synthetic analogs modify the growth and the morphology of Pyrus communis pollen tubes affecting ROS levels and causing cell death 182
LC determination of leuprolide component amino acids in injectable solution by phanquinone pre-column derivatization labelling procedure 181
Study of the cytotoxic effects of the new synthetic isothiocyanate CM9 and its fullerene derivative on human T-leukemia cells 181
Polyamine Conjugation as a Promising Strategy To Target Amyloid Aggregation in the Framework of Alzheimer’s Disease 180
Design, Synthesis, and biological evaluation of naphtalene diimides derivatives as anticancer agent 179
Process for preparation of 1,4-benzoquinone-2,5-diamines by reaction of amines with 1,4-benzoquinones bearing leaving groups at the 2- and 5-positions 178
Synthetic polyamines activating autophagy: Effects on cancer cell death 175
Design, synthesis, and biological evaluation of pirenzepine analogs bearing a 1,2-cyclohexanediamine and a perhydroquinoxaline units in exchange for the piperazine ring as antimuscarinics 172
Exploiting RNA as a new biomolecular target for synthetic polyamines 172
Macrocyclic naphthalene diimides as G-quadruplex binders 171
Design, synthesis, and biological evaluation of substituted naphtalene imides and diimides as anticancer agents 169
Inhibition of Acetylcholinesterase, Beta-Amyloid Aggregation, and NMDA Receptors in Alzheimer's Disease: A Promising Direction for the Multi-target-Directed Ligands Gold Rush 167
Exploring the effects of isothiocyanates on chemotherapeutic drugs 167
Multitarget-directed ligands: Innovative chemical probes and therapeutic tools against Alzheimer's disease 167
Preparation, characterization and in vitro evaluation of sterically stabilized liposome containing a naphthalenediimide derivative as anticancer agent 164
Novel Class of Quinone-Bearing Polyamines as Multi-Target-Directed Ligands To Combat Alzheimer's Disease 163
Exploration of the Neuromodulatory Properties of Fyn and GSK-3β Kinases Exploiting 7-Azaindole-Based Inhibitors 162
Lipocrine, a multipotent drug for the investigation of Alzheimer's disease 160
New quinazoline compounds as non-peptidomimetic BACE-1 inhibitors in the treatment of Alzheimer's disease 159
Synthesis of Monomeric Derivatives To Probe Memoquin's Bivalent Interactions 159
Combined inhibition of the EGFR/AKT pathways by a novel conjugate of quinazoline with isothiocyanate. 159
Analysis of the muscarinic receptor subtype mediating inhibition of the neurogenic contractions in rabbit isolated vas deferens by a series of polymethylene tetra-amines 158
Progress in acetylcholinesterase inhibitors for Alzheimer's disease: an update 158
Polyamine–Drug Conjugates: Do They Boost Drug Activity? 157
An optimized polyamine moiety boosts the potency of human type II topoisomerase poisons as quantified by comparative analysis centered on the clinical candidate F14512 156
Polyamine-containing etoposide derivatives as poisons of human type II topoisomerases: Differential effects on topoisomerase IIα and IIβ 155
Cytotoxicity of Methoctramine and related Spermine analogues 154
Multifunctional Tacrine Derivatives in Alzheimer’s Disease 154
Oxidative stress in Alzheimer’s disease: are we connecting the dots? 154
Cystamine-tacrine dimer: a new multi-target-directed ligand as potential therapeutic agent for Alzheimer’s disease treatment 154
Beta-secretase monolithic micro-IMER (immobilized enzyme reactor) for on-line HPLC screening of quinone-bearing polyamine inhibitors. 153
Multi-target Design Strategies in the Context of Alzheimer's Disease: Acetylcholinesterase Inhibition and NMDA Receptor Antagonism as the Driving Forces 153
Preliminary evaluation of the cytotoxicity of naphthalene diimide-polyamine conjugates in human cancer cells 153
One-molecule-multiple-target strategy: a novel multifunctional molecule designed to block EGF-r and to exert pro-apoptotic effects 152
Heterocyclic inhibitors of AChE acylation and peripheral sites. 151
Multi-target-Directed Ligands To Combat Neurodegenerative Diseases 149
Novel targets for “old” polyamine analogues: monoamine oxidases and benextramine derivatives 149
Benextramine derivatives as probes to target human monoamine oxidases 147
Progress in acetylcholinesterase inhibitors for Alzheimer's disease 146
Structure-activity relationships of methoctramine-related polyamines as muscarinic antagonist: Effect of replacing the inner polymethylene chain with cyclic moieties 146
MTDL design strategy in the context of Alzheimer's disease: from lipocrine to memoquin and beyond 144
In vitro and in vivo evaluation of polymethylene tetraamine derivatives as NMDA receptor channel blockers 144
Distinct biological responses of metastatic castration resistant prostate cancer cells upon exposure to G-quadruplex interacting naphthalenediimide derivatives 143
Multi-Target-Direcetd Ligands as acetylcholinesterase inhibitors and nicotinic modulators for Alzheimer's disease 142
Structure-Activity Relationships of Acetylcholinesterase Noncovalent Inhibitors Based on a Polyamine Backbone. 4. Futher Investigation on the Inner Spacer. 142
Discovery of Memoquin, a Multitarget-Directed Ligand (MTDL) for the Treatment of Alzheimer’s Disease 141
null 141
Polymethylene tetraamine backbone as template for the development of biologically active polyamines 140
Synthetic polyamines as potential amine oxidase inhibitors: a preliminary study. 140
Cytotoxicity of methoctramine-related polyamines 139
Naphthalene diimide-polyamine hybrids as antiproliferative agents: Focus on the architecture of the polyamine chains 139
Natural-product-inspired modulators of Alzheimer’s disease: focus on amyloid and oxidative stress 138
Role of Fyn Kinase Inhibitors in Switching Neuroinflammatory Pathways 138
Methoctramine-related polyamines as antinociceptive agents 137
Polyamines may modulate both G protein-coupled receptors and G proteins 137
Structure-Activity Relationships of New Acetylcholinesterase Noncovalent Inhibitors Based on a Polyamine Backbone 136
Methoctramine analogues inhibit responses to capsaicin and protons in rat dorsal root ganglion neurons 136
Novel polyamine analogues: from substrates towards potential inhibitors of monoamine oxidases 136
Discovery of multipotent drugs for the teratment of Alzheimer's disease 134
Recent advances in alpha1-adrenoreceptor antagonists as pharmacological tools and therapeutic agents. 134
Methoctramine analogues inhibit responses to capsaicin in DRG neurons and cloned TRPV1 133
From dual binding site acetylcholinesterase inhibitors to multi-target-directed ligands (MTDLs): a step forward in the treatment of Alzheimer's disease 133
Inibitori delle fosfodiesterasi 133
Ottimizzazione del lead: metodi tradizionali 133
Polyamines in Drug Discovery: From the Universal Template Approach to the Multitarget-Directed Ligand Design Strategy 133
Rational design of multitarget-directed antioxidants: merging memoquin and lipocrine molecular frameworks 132
Quinone-bearing polyamines are AChE inhibitors endowed with multifunctional properties 129
Synthetic polyamines: an overview of their multiple biological activities. 129
Totale 19.986
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Categoria #
all - tutte 69.359
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 4.525
Totale 73.884
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20222.482 0 92 163 190 249 180 99 201 141 263 481 423
2022/20232.609 277 321 123 297 150 174 179 148 475 72 233 160
2023/20241.675 70 161 113 122 126 286 95 141 120 126 135 180
2024/20253.828 280 510 398 308 710 224 250 153 98 186 165 546
2025/20267.479 423 640 739 519 870 415 799 277 1.485 565 418 329
2026/2027482 198 284 0 0 0 0 0 0 0 0 0 0
Totale 25.573