CRIS Current Research Information System

MINARINI, ANNA
 Distribuzione geografica
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Continente #
EU - Europa 6.820
NA - Nord America 6.369
AS - Asia 1.976
AF - Africa 402
SA - Sud America 22
Continente sconosciuto - Info sul continente non disponibili 18
OC - Oceania 7
Totale 15.614
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Nazione #
US - Stati Uniti d'America 6.357
IT - Italia 3.131
GB - Regno Unito 1.282
CN - Cina 912
SG - Singapore 564
DE - Germania 536
SE - Svezia 490
UA - Ucraina 358
FR - Francia 247
IN - India 238
IE - Irlanda 191
RU - Federazione Russa 171
TG - Togo 162
VN - Vietnam 111
CI - Costa d'Avorio 102
EE - Estonia 93
ZA - Sudafrica 93
BG - Bulgaria 61
JO - Giordania 46
CH - Svizzera 35
BE - Belgio 32
SC - Seychelles 31
ES - Italia 25
NL - Olanda 25
HR - Croazia 24
JP - Giappone 19
ID - Indonesia 18
EU - Europa 17
FI - Finlandia 17
PL - Polonia 16
CZ - Repubblica Ceca 15
GR - Grecia 14
IR - Iran 13
KR - Corea 13
LU - Lussemburgo 13
CA - Canada 12
TR - Turchia 10
AT - Austria 9
CL - Cile 9
RO - Romania 9
LB - Libano 7
NG - Nigeria 7
AU - Australia 6
PK - Pakistan 6
BR - Brasile 5
AL - Albania 4
CO - Colombia 4
LT - Lituania 4
MT - Malta 4
MY - Malesia 4
TW - Taiwan 4
SA - Arabia Saudita 3
SK - Slovacchia (Repubblica Slovacca) 3
DK - Danimarca 2
DZ - Algeria 2
LV - Lettonia 2
MA - Marocco 2
NO - Norvegia 2
PT - Portogallo 2
SM - San Marino 2
TH - Thailandia 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AZ - Azerbaigian 1
BD - Bangladesh 1
BO - Bolivia 1
EC - Ecuador 1
EG - Egitto 1
FK - Isole Falkland (Malvinas) 1
HU - Ungheria 1
IQ - Iraq 1
LK - Sri Lanka 1
MU - Mauritius 1
NZ - Nuova Zelanda 1
PE - Perù 1
PH - Filippine 1
TN - Tunisia 1
UZ - Uzbekistan 1
Totale 15.614
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Città #
Southend 1.152
Fairfield 725
Ashburn 556
Singapore 497
Chandler 496
Santa Clara 439
Woodbridge 356
Houston 349
Wilmington 316
Seattle 305
Bologna 303
Princeton 272
Ann Arbor 265
Cambridge 244
Jacksonville 237
Dublin 188
Boardman 176
Lomé 162
Milan 154
Rome 148
Padova 144
Westminster 121
Nanjing 118
Abidjan 102
Dong Ket 101
Berlin 79
New York 77
Jinan 70
Saint Petersburg 61
Sofia 61
Shenyang 58
Florence 55
Medford 54
Turin 54
Hebei 53
Redmond 51
Redwood City 51
Amman 46
Palermo 45
Beijing 41
Mülheim 41
Changsha 40
San Diego 40
Naples 38
Nanchang 37
Catania 33
Guangzhou 33
Los Angeles 32
Bari 31
Falls Church 31
Tianjin 31
Hangzhou 30
Mahé 29
Brussels 28
Parma 26
Zhengzhou 26
Reggio Emilia 25
Dearborn 24
Benevento 23
Jiaxing 22
Norwalk 22
Des Moines 21
Shanghai 21
Haikou 20
Genoa 19
Verona 18
Jakarta 17
Taiyuan 17
Modena 16
Olalla 15
Bremen 13
Cesena 13
Helsinki 13
Ningbo 13
Siracusa 13
Strassen 13
Ancona 12
Fuzhou 12
Harbin 12
Livorno 12
Mountain View 12
Napoli 11
Ravenna 11
Tokyo 11
Barcelona 10
Caserta 10
Chicago 10
Cormano 10
Lanzhou 10
Paris 10
Brescia 9
Buffalo 9
Dallas 9
Kunming 9
Monza 9
Phoenix 9
Rimini 9
Taizhou 9
Andover 8
Angri 8
Totale 9.907
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Nome #
Farmaci che agiscono sul sistema renina-angiotensina 1.342
Trasportatori di membrana dei farmaci 661
Antidepressivi e antipsicotici 412
Progettazione e sintesi di analoghi rigidi di metoctramina nello studio dei recettori muscarinici 195
Novel Polyamine–Naphthalene Diimide Conjugates Targeting Histone Deacetylases and DNA for Cancer Phenotype Reprogramming 181
Cytotoxicity of methoctramine and methoctramine-related polyamines. 178
Alzheimer's disease: new approaches to drug discovery. 160
Structure-activity relationships of acetylcholinesterase noncovalent inhibitors based on a polyamine backbone. 3. Effect of replacing the inner polymethylene chain with cyclic moieties 158
Progettazione e sintesi di poliammine a potenziale attività antitumorale 154
Nature-Inspired Multifunctional Ligands: Focusing on Amyloid-Based Molecular Mechanisms of Alzheimer’s Disease 153
Rational Approach to discover multipotent anti-Alzheimer drugs 152
DESIGN, SYNTHESIS AND BIOLOGICAL EVALUATION OF SUSTITUTED NAPHTHALENE IMIDES AND DIIMIDES AS ANTICANCER AGENT 152
Design, synthesis, and biological evaluation of conformationally restricted rivastigmine analogues 151
Benextramine and derivatives as novel human monoamine oxidases inhibitors: an integrated approach 148
Merging memantine and ferulic acid to probe connections between NMDA receptors, oxidative stress and amyloid-β peptide in Alzheimer's disease 148
Pharmacophore Hybridization To Discover Novel Topoisomerase II Poisons with Promising Antiproliferative Activity 147
Progettazione e sintesi di derivati poliamminici per il trattamento della malattia di Alzheimer 145
Polyamine conjugation of curcumin analogues toward the discovery of mitochondria-directed neuroprotective agents. 145
Structure-activity relationships of novel substituted naphthalene diimides as anticancer agents 141
null 141
Exploring the activity of polyamine analogues on polyamine and spermine oxidase: methoctramine, a potent and selective inhibitor of polyamine oxidase 137
Cystamine-tacrine dimer: A new multi-target-directed ligand as potential therapeutic agent for Alzheimer's disease treatment. 136
Multitargeted drugs discovery: Balancing anti-amyloid and anticholinesterase capacity in a single chemical entity 133
Design and synthesis of new multitarget agents for the study of neuroinflammation in Alzheimer's disease 128
LC determination of leuprolide component amino acids in injectable solution by phanquinone pre-column derivatization labelling procedure 124
Process for preparation of 1,4-benzoquinone-2,5-diamines by reaction of amines with 1,4-benzoquinones bearing leaving groups at the 2- and 5-positions 124
Design, synthesis, and biological evaluation of pirenzepine analogs bearing a 1,2-cyclohexanediamine and a perhydroquinoxaline units in exchange for the piperazine ring as antimuscarinics 123
Macrocyclic naphthalene diimides as G-quadruplex binders 123
Natural polyamines and synthetic analogs modify the growth and the morphology of Pyrus communis pollen tubes affecting ROS levels and causing cell death 123
Lights and shadows of electrophile signaling: Focus on the Nrf2-Keap1 pathway 122
In vivo characterization of ARN14140, a memantine/galantamine-based multi-target compound for Alzheimer's disease 120
Study of the cytotoxic effects of the new synthetic isothiocyanate CM9 and its fullerene derivative on human T-leukemia cells 117
Synthetic polyamines activating autophagy: Effects on cancer cell death 115
Novel Class of Quinone-Bearing Polyamines as Multi-Target-Directed Ligands To Combat Alzheimer's Disease 115
Multi-target Design Strategies in the Context of Alzheimer's Disease: Acetylcholinesterase Inhibition and NMDA Receptor Antagonism as the Driving Forces 114
Exploiting RNA as a new biomolecular target for synthetic polyamines 114
Polyamine Conjugation as a Promising Strategy To Target Amyloid Aggregation in the Framework of Alzheimer’s Disease 114
Exploring the effects of isothiocyanates on chemotherapeutic drugs 114
Multitarget-directed ligands: Innovative chemical probes and therapeutic tools against Alzheimer's disease 114
Heterocyclic inhibitors of AChE acylation and peripheral sites. 112
Beta-secretase monolithic micro-IMER (immobilized enzyme reactor) for on-line HPLC screening of quinone-bearing polyamine inhibitors. 111
Multi-target-Directed Ligands To Combat Neurodegenerative Diseases 111
Preparation, characterization and in vitro evaluation of sterically stabilized liposome containing a naphthalenediimide derivative as anticancer agent 111
Cytotoxicity of Methoctramine and related Spermine analogues 109
Synthetic polyamines as potential amine oxidase inhibitors: a preliminary study. 109
An optimized polyamine moiety boosts the potency of human type II topoisomerase poisons as quantified by comparative analysis centered on the clinical candidate F14512 109
Memantine Derivatives as Multitarget Agents in Alzheimer’s Disease 109
Progress in acetylcholinesterase inhibitors for Alzheimer's disease: an update 108
Structure-activity relationships of methoctramine-related polyamines as muscarinic antagonist: Effect of replacing the inner polymethylene chain with cyclic moieties 107
Inhibition of Acetylcholinesterase, Beta-Amyloid Aggregation, and NMDA Receptors in Alzheimer's Disease: A Promising Direction for the Multi-target-Directed Ligands Gold Rush 107
Design, Synthesis, and biological evaluation of naphtalene diimides derivatives as anticancer agent 107
null 107
Benextramine derivatives as probes to target human monoamine oxidases 106
Oxidative stress in Alzheimer’s disease: are we connecting the dots? 105
Preliminary evaluation of the cytotoxicity of naphthalene diimide-polyamine conjugates in human cancer cells 104
null 104
Progress in acetylcholinesterase inhibitors for Alzheimer's disease 103
Multifunctional Tacrine Derivatives in Alzheimer’s Disease 103
Synthesis of Monomeric Derivatives To Probe Memoquin's Bivalent Interactions 102
MTDL design strategy in the context of Alzheimer's disease: from lipocrine to memoquin and beyond 101
From dual binding site acetylcholinesterase inhibitors to multi-target-directed ligands (MTDLs): a step forward in the treatment of Alzheimer's disease 100
Polyamine-containing etoposide derivatives as poisons of human type II topoisomerases: Differential effects on topoisomerase IIα and IIβ 100
Multi-Target-Direcetd Ligands as acetylcholinesterase inhibitors and nicotinic modulators for Alzheimer's disease 98
Lipocrine, a multipotent drug for the investigation of Alzheimer's disease 97
In vitro and in vivo evaluation of polymethylene tetraamine derivatives as NMDA receptor channel blockers 97
Cystamine-tacrine dimer: a new multi-target-directed ligand as potential therapeutic agent for Alzheimer’s disease treatment 97
Polyamines may modulate both G protein-coupled receptors and G proteins 97
Methoctramine analogues inhibit responses to capsaicin and protons in rat dorsal root ganglion neurons 97
Design, synthesis, and biological evaluation of substituted naphtalene imides and diimides as anticancer agents 96
Structure-Activity Relationships of New Acetylcholinesterase Noncovalent Inhibitors Based on a Polyamine Backbone 95
null 94
Discovery of multipotent drugs for the teratment of Alzheimer's disease 93
Lipoic acid, a lead structure for multi-target-directed drugs for neurodegeneration 93
Structure-Activity Relationships of Acetylcholinesterase Noncovalent Inhibitors Based on a Polyamine Backbone. 4. Futher Investigation on the Inner Spacer. 92
Novel polyamine analogues: from substrates towards potential inhibitors of monoamine oxidases 92
Polymethylene tetraamine backbone as template for the development of biologically active polyamines 91
Synthetic polyamines: an overview of their multiple biological activities. 91
Cytotoxicity of methoctramine-related polyamines 90
Rational design of multitarget-directed antioxidants: merging memoquin and lipocrine molecular frameworks 90
One-molecule-multiple-target strategy: a novel multifunctional molecule designed to block EGF-r and to exert pro-apoptotic effects 89
Synthetic polyamines as potential amine oxidases inhibitors: a preliminary study 89
Inibitori delle fosfodiesterasi 88
Discovery of Memoquin, a Multitarget-Directed Ligand (MTDL) for the Treatment of Alzheimer’s Disease 88
Tacrine Derivatives and Alzheimer's Disease 87
Quinone-bearing polyamines are AChE inhibitors endowed with multifunctional properties 86
New quinazoline compounds as non-peptidomimetic BACE-1 inhibitors in the treatment of Alzheimer's disease 86
Novel targets for “old” polyamine analogues: monoamine oxidases and benextramine derivatives 85
Bovine Serum Amine Oxidase and Polyamine Analogues: Chemical Synthesis and Biological Evaluation Integrated with Molecular Docking and 3-D QSAR Studies 84
Novel polyamine analogues: from substrates towards potential inhibitors of monoamine oxidases. 84
Polyamines in Drug Discovery: From the Universal Template Approach to the Multitarget-Directed Ligand Design Strategy 84
Recent advances in the design and synthesis of prazosin derivatives 84
Recent advances in alpha1-adrenoreceptor antagonists as pharmacological tools and therapeutic agents. 83
Ottimizzazione del lead: metodi tradizionali 83
null 83
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Distinct biological responses of metastatic castration resistant prostate cancer cells upon exposure to G-quadruplex interacting naphthalenediimide derivatives 82
Rational approach to discover multipotent anti-Alzheimer drugs 81
null 81
Methoctramine effects on nicotinic acetylcholine receptor kinetics 80
null 79
Totale 13.188
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Categoria #
all - tutte 39.616
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 3.016
Totale 42.632
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20202.578 0 0 0 0 286 312 414 520 432 231 191 192
2020/20212.021 411 138 67 111 107 162 85 208 215 134 119 264
2021/20222.626 144 92 163 190 249 180 99 201 141 263 481 423
2022/20232.631 277 324 125 297 154 174 182 149 479 73 235 162
2023/20241.681 70 161 114 123 126 288 95 142 120 126 135 181
2024/20252.197 282 516 401 310 688 0 0 0 0 0 0 0
Totale 16.009