MINARINI, ANNA
 Distribuzione geografica
Continente #
EU - Europa 8.418
NA - Nord America 7.933
AS - Asia 6.479
AF - Africa 620
SA - Sud America 315
Continente sconosciuto - Info sul continente non disponibili 19
OC - Oceania 10
Totale 23.794
Nazione #
US - Stati Uniti d'America 7.846
IT - Italia 3.890
CN - Cina 1.887
SG - Singapore 1.830
VN - Vietnam 1.348
GB - Regno Unito 1.340
DE - Germania 645
SE - Svezia 507
HK - Hong Kong 498
FR - Francia 407
UA - Ucraina 362
IN - India 332
RU - Federazione Russa 306
CI - Costa d'Avorio 214
NL - Olanda 210
BR - Brasile 198
IE - Irlanda 195
TG - Togo 160
ZA - Sudafrica 132
JP - Giappone 127
EE - Estonia 94
KR - Corea 94
FI - Finlandia 86
BG - Bulgaria 61
CA - Canada 51
SC - Seychelles 49
JO - Giordania 48
AR - Argentina 43
ES - Italia 42
CH - Svizzera 41
PH - Filippine 40
BE - Belgio 38
ID - Indonesia 38
TH - Thailandia 36
PL - Polonia 29
TR - Turchia 28
TW - Taiwan 27
IQ - Iraq 26
MX - Messico 26
HR - Croazia 25
EC - Ecuador 24
GR - Grecia 23
BD - Bangladesh 22
PK - Pakistan 22
AT - Austria 20
EU - Europa 17
CZ - Repubblica Ceca 15
LT - Lituania 15
CO - Colombia 14
IR - Iran 14
CL - Cile 13
LU - Lussemburgo 13
RO - Romania 13
MA - Marocco 11
SA - Arabia Saudita 10
LB - Libano 9
UZ - Uzbekistan 9
AL - Albania 8
AU - Australia 8
EG - Egitto 8
MY - Malesia 8
NG - Nigeria 8
TN - Tunisia 8
ET - Etiopia 7
PE - Perù 7
PY - Paraguay 7
AZ - Azerbaigian 5
IL - Israele 5
KE - Kenya 5
PT - Portogallo 5
SK - Slovacchia (Repubblica Slovacca) 5
MT - Malta 4
NP - Nepal 4
VE - Venezuela 4
DO - Repubblica Dominicana 3
DZ - Algeria 3
HU - Ungheria 3
LV - Lettonia 3
LY - Libia 3
NO - Norvegia 3
AE - Emirati Arabi Uniti 2
BO - Bolivia 2
BY - Bielorussia 2
CR - Costa Rica 2
DK - Danimarca 2
GH - Ghana 2
GT - Guatemala 2
KZ - Kazakistan 2
LK - Sri Lanka 2
MU - Mauritius 2
NZ - Nuova Zelanda 2
OM - Oman 2
RS - Serbia 2
SM - San Marino 2
UY - Uruguay 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AG - Antigua e Barbuda 1
AO - Angola 1
BH - Bahrain 1
BJ - Benin 1
Totale 23.779
Città #
Singapore 1.231
Southend 1.152
Ashburn 773
Fairfield 725
Chandler 493
Hong Kong 482
Santa Clara 453
San Jose 424
Bologna 360
Woodbridge 356
Houston 352
Ho Chi Minh City 338
Wilmington 318
Seattle 307
Hanoi 286
Princeton 272
Ann Arbor 265
Cambridge 244
Beijing 239
Jacksonville 237
Milan 234
Abidjan 214
Hefei 211
Rome 208
Dublin 191
Boardman 178
Lomé 160
Padova 149
Dallas 131
Los Angeles 128
Lauterbourg 121
Nanjing 121
Westminster 121
New York 106
Tokyo 105
Dong Ket 101
Berlin 78
Jinan 74
Buffalo 69
Florence 69
Seoul 66
Helsinki 65
Naples 65
Shenyang 63
Saint Petersburg 61
Sofia 61
Turin 61
Council Bluffs 60
Haiphong 60
Palermo 56
Guangzhou 55
Medford 54
Hebei 53
Bari 52
Changsha 51
Redmond 51
Redwood City 51
Amman 48
Da Nang 44
Munich 44
Mülheim 41
Redondo Beach 41
San Diego 40
Catania 39
Nanchang 38
Shanghai 37
Zhengzhou 36
Tianjin 35
Verona 35
Brussels 34
Falls Church 31
Genoa 30
Hangzhou 30
Yubileyny 30
Frankfurt am Main 29
Johannesburg 29
Mahé 29
Parma 27
Reggio Emilia 25
Dearborn 24
Benevento 23
Jiaxing 23
Orem 23
Chicago 22
Norwalk 22
Des Moines 21
Haikou 21
Phoenix 21
São Paulo 21
Bengaluru 20
Modena 20
Montreal 20
Jakarta 19
London 19
Taiyuan 19
Biên Hòa 18
Falkenstein 18
Warsaw 18
Bangkok 17
Atlanta 16
Totale 14.258
Nome #
Farmaci che agiscono sul sistema renina-angiotensina 1.646
Trasportatori di membrana dei farmaci 867
Antidepressivi e antipsicotici 721
Benextramine and derivatives as novel human monoamine oxidases inhibitors: an integrated approach 265
Galantamine-memantine hybrids for Alzheimer's disease: The influence of linker rigidity in biological activity and pharmacokinetic properties 256
Novel Polyamine–Naphthalene Diimide Conjugates Targeting Histone Deacetylases and DNA for Cancer Phenotype Reprogramming 250
Progettazione e sintesi di analoghi rigidi di metoctramina nello studio dei recettori muscarinici 237
Bovine Serum Amine Oxidase and Polyamine Analogues: Chemical Synthesis and Biological Evaluation Integrated with Molecular Docking and 3-D QSAR Studies 230
Cytotoxicity of methoctramine and methoctramine-related polyamines. 228
Progettazione e sintesi di poliammine a potenziale attività antitumorale 226
Merging memantine and ferulic acid to probe connections between NMDA receptors, oxidative stress and amyloid-β peptide in Alzheimer's disease 223
DESIGN, SYNTHESIS AND BIOLOGICAL EVALUATION OF SUSTITUTED NAPHTHALENE IMIDES AND DIIMIDES AS ANTICANCER AGENT 221
Nature-Inspired Multifunctional Ligands: Focusing on Amyloid-Based Molecular Mechanisms of Alzheimer’s Disease 215
Rational Approach to discover multipotent anti-Alzheimer drugs 214
Structure-activity relationships of acetylcholinesterase noncovalent inhibitors based on a polyamine backbone. 3. Effect of replacing the inner polymethylene chain with cyclic moieties 208
Polyamine conjugation of curcumin analogues toward the discovery of mitochondria-directed neuroprotective agents. 203
Pharmacophore Hybridization To Discover Novel Topoisomerase II Poisons with Promising Antiproliferative Activity 203
Exploring the activity of polyamine analogues on polyamine and spermine oxidase: methoctramine, a potent and selective inhibitor of polyamine oxidase 200
Design, synthesis, and biological evaluation of conformationally restricted rivastigmine analogues 199
Design and synthesis of new multitarget agents for the study of neuroinflammation in Alzheimer's disease 195
Progettazione e sintesi di derivati poliamminici per il trattamento della malattia di Alzheimer 193
Alzheimer's disease: new approaches to drug discovery. 193
Structure-activity relationships of novel substituted naphthalene diimides as anticancer agents 193
Multitargeted drugs discovery: Balancing anti-amyloid and anticholinesterase capacity in a single chemical entity 192
In vivo characterization of ARN14140, a memantine/galantamine-based multi-target compound for Alzheimer's disease 182
Lights and shadows of electrophile signaling: Focus on the Nrf2-Keap1 pathway 180
Cystamine-tacrine dimer: A new multi-target-directed ligand as potential therapeutic agent for Alzheimer's disease treatment. 178
Novel polyamine-based Histone deacetylases-Lysine demethylase 1 dual binding inhibitors 178
Memantine Derivatives as Multitarget Agents in Alzheimer’s Disease 178
Design, Synthesis, and biological evaluation of naphtalene diimides derivatives as anticancer agent 177
Study of the cytotoxic effects of the new synthetic isothiocyanate CM9 and its fullerene derivative on human T-leukemia cells 176
Double Attack to Oxidative Stress in Neurodegenerative Disorders: MAO-B and Nrf2 as Elected Targets 175
Natural polyamines and synthetic analogs modify the growth and the morphology of Pyrus communis pollen tubes affecting ROS levels and causing cell death 175
Inhibition of β-Amyloid Aggregation in Alzheimer's Disease: The Key Role of (Pro)electrophilic Warheads 173
LC determination of leuprolide component amino acids in injectable solution by phanquinone pre-column derivatization labelling procedure 171
Synthetic polyamines activating autophagy: Effects on cancer cell death 168
Macrocyclic naphthalene diimides as G-quadruplex binders 168
Polyamine Conjugation as a Promising Strategy To Target Amyloid Aggregation in the Framework of Alzheimer’s Disease 168
Design, synthesis, and biological evaluation of pirenzepine analogs bearing a 1,2-cyclohexanediamine and a perhydroquinoxaline units in exchange for the piperazine ring as antimuscarinics 165
Exploiting RNA as a new biomolecular target for synthetic polyamines 165
Process for preparation of 1,4-benzoquinone-2,5-diamines by reaction of amines with 1,4-benzoquinones bearing leaving groups at the 2- and 5-positions 164
Design, synthesis, and biological evaluation of substituted naphtalene imides and diimides as anticancer agents 164
Multitarget-directed ligands: Innovative chemical probes and therapeutic tools against Alzheimer's disease 163
Inhibition of Acetylcholinesterase, Beta-Amyloid Aggregation, and NMDA Receptors in Alzheimer's Disease: A Promising Direction for the Multi-target-Directed Ligands Gold Rush 160
Novel, Potent, and Druglike Tetrahydroquinazoline Inhibitor That Is Highly Selective for Human Topoisomerase II α over β 159
Preparation, characterization and in vitro evaluation of sterically stabilized liposome containing a naphthalenediimide derivative as anticancer agent 158
Novel Class of Quinone-Bearing Polyamines as Multi-Target-Directed Ligands To Combat Alzheimer's Disease 158
Progress in acetylcholinesterase inhibitors for Alzheimer's disease: an update 155
Synthesis of Monomeric Derivatives To Probe Memoquin's Bivalent Interactions 154
Analysis of the muscarinic receptor subtype mediating inhibition of the neurogenic contractions in rabbit isolated vas deferens by a series of polymethylene tetra-amines 153
An optimized polyamine moiety boosts the potency of human type II topoisomerase poisons as quantified by comparative analysis centered on the clinical candidate F14512 153
Polyamine-containing etoposide derivatives as poisons of human type II topoisomerases: Differential effects on topoisomerase IIα and IIβ 153
Exploring the effects of isothiocyanates on chemotherapeutic drugs 153
Multifunctional Tacrine Derivatives in Alzheimer’s Disease 152
Multi-target Design Strategies in the Context of Alzheimer's Disease: Acetylcholinesterase Inhibition and NMDA Receptor Antagonism as the Driving Forces 152
Lipocrine, a multipotent drug for the investigation of Alzheimer's disease 151
Cystamine-tacrine dimer: a new multi-target-directed ligand as potential therapeutic agent for Alzheimer’s disease treatment 151
Oxidative stress in Alzheimer’s disease: are we connecting the dots? 150
Combined inhibition of the EGFR/AKT pathways by a novel conjugate of quinazoline with isothiocyanate. 150
New quinazoline compounds as non-peptidomimetic BACE-1 inhibitors in the treatment of Alzheimer's disease 149
Polyamine–Drug Conjugates: Do They Boost Drug Activity? 148
Preliminary evaluation of the cytotoxicity of naphthalene diimide-polyamine conjugates in human cancer cells 148
One-molecule-multiple-target strategy: a novel multifunctional molecule designed to block EGF-r and to exert pro-apoptotic effects 147
Multi-target-Directed Ligands To Combat Neurodegenerative Diseases 147
Beta-secretase monolithic micro-IMER (immobilized enzyme reactor) for on-line HPLC screening of quinone-bearing polyamine inhibitors. 145
Cytotoxicity of Methoctramine and related Spermine analogues 145
Novel targets for “old” polyamine analogues: monoamine oxidases and benextramine derivatives 145
Heterocyclic inhibitors of AChE acylation and peripheral sites. 143
In vitro and in vivo evaluation of polymethylene tetraamine derivatives as NMDA receptor channel blockers 143
Structure-Activity Relationships of Acetylcholinesterase Noncovalent Inhibitors Based on a Polyamine Backbone. 4. Futher Investigation on the Inner Spacer. 142
MTDL design strategy in the context of Alzheimer's disease: from lipocrine to memoquin and beyond 141
null 141
Distinct biological responses of metastatic castration resistant prostate cancer cells upon exposure to G-quadruplex interacting naphthalenediimide derivatives 140
Structure-activity relationships of methoctramine-related polyamines as muscarinic antagonist: Effect of replacing the inner polymethylene chain with cyclic moieties 139
Benextramine derivatives as probes to target human monoamine oxidases 139
Multi-Target-Direcetd Ligands as acetylcholinesterase inhibitors and nicotinic modulators for Alzheimer's disease 137
Synthetic polyamines as potential amine oxidase inhibitors: a preliminary study. 137
Progress in acetylcholinesterase inhibitors for Alzheimer's disease 136
Cytotoxicity of methoctramine-related polyamines 136
Discovery of Memoquin, a Multitarget-Directed Ligand (MTDL) for the Treatment of Alzheimer’s Disease 135
Polymethylene tetraamine backbone as template for the development of biologically active polyamines 134
Natural-product-inspired modulators of Alzheimer’s disease: focus on amyloid and oxidative stress 134
Structure-Activity Relationships of New Acetylcholinesterase Noncovalent Inhibitors Based on a Polyamine Backbone 134
Novel polyamine analogues: from substrates towards potential inhibitors of monoamine oxidases 134
Ottimizzazione del lead: metodi tradizionali 132
Polyamines may modulate both G protein-coupled receptors and G proteins 131
From dual binding site acetylcholinesterase inhibitors to multi-target-directed ligands (MTDLs): a step forward in the treatment of Alzheimer's disease 130
Methoctramine analogues inhibit responses to capsaicin and protons in rat dorsal root ganglion neurons 130
Naphthalene diimide-polyamine hybrids as antiproliferative agents: Focus on the architecture of the polyamine chains 130
Methoctramine-related polyamines as antinociceptive agents 129
Methoctramine analogues inhibit responses to capsaicin in DRG neurons and cloned TRPV1 129
Multi-Target-Directed Drug Design Strategy: Development of new Naphthalene Diimides Bearing Isothiocyanate Functionality As Anticancer Agents 127
Polyamines in Drug Discovery: From the Universal Template Approach to the Multitarget-Directed Ligand Design Strategy 127
Discovery of multipotent drugs for the teratment of Alzheimer's disease 125
Synthetic polyamines: an overview of their multiple biological activities. 125
Rational design of multitarget-directed antioxidants: merging memoquin and lipocrine molecular frameworks 125
Recent advances in alpha1-adrenoreceptor antagonists as pharmacological tools and therapeutic agents. 123
Role of Fyn Kinase Inhibitors in Switching Neuroinflammatory Pathways 123
From Monoamine Oxidase Inhibition to Antiproliferative Activity: New Biological Perspectives for Polyamine Analogs 123
Inibitori delle fosfodiesterasi 122
Totale 19.058
Categoria #
all - tutte 62.825
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 4.205
Totale 67.030


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021517 0 0 0 0 0 0 0 0 0 134 119 264
2021/20222.626 144 92 163 190 249 180 99 201 141 263 481 423
2022/20232.609 277 321 123 297 150 174 179 148 475 72 233 160
2023/20241.675 70 161 113 122 126 286 95 141 120 126 135 180
2024/20253.828 280 510 398 308 710 224 250 153 98 186 165 546
2025/20266.639 423 640 739 519 870 415 799 277 1.485 472 0 0
Totale 24.251