CRIS Current Research Information System

MINARINI, ANNA
 Distribuzione geografica
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Continente #
EU - Europa 7.959
NA - Nord America 7.166
AS - Asia 4.757
AF - Africa 565
SA - Sud America 271
Continente sconosciuto - Info sul continente non disponibili 18
OC - Oceania 8
Totale 20.744
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Nazione #
US - Stati Uniti d'America 7.101
IT - Italia 3.706
CN - Cina 1.689
SG - Singapore 1.642
GB - Regno Unito 1.311
DE - Germania 627
SE - Svezia 505
HK - Hong Kong 478
UA - Ucraina 361
VN - Vietnam 331
RU - Federazione Russa 304
IN - India 284
FR - Francia 278
CI - Costa d'Avorio 214
IE - Irlanda 193
NL - Olanda 184
BR - Brasile 174
TG - Togo 160
ZA - Sudafrica 108
EE - Estonia 93
JP - Giappone 93
KR - Corea 77
BG - Bulgaria 61
SC - Seychelles 49
FI - Finlandia 45
JO - Giordania 45
ES - Italia 41
CA - Canada 40
BE - Belgio 38
CH - Svizzera 38
AR - Argentina 36
ID - Indonesia 29
PL - Polonia 27
HR - Croazia 24
EC - Ecuador 22
MX - Messico 22
AT - Austria 20
GR - Grecia 20
EU - Europa 17
CZ - Repubblica Ceca 15
IR - Iran 14
TR - Turchia 14
CL - Cile 13
LU - Lussemburgo 13
LT - Lituania 12
RO - Romania 11
CO - Colombia 9
PK - Pakistan 9
AU - Australia 7
LB - Libano 7
MA - Marocco 7
NG - Nigeria 7
AL - Albania 6
BD - Bangladesh 6
PE - Perù 6
PY - Paraguay 6
MY - Malesia 5
SK - Slovacchia (Repubblica Slovacca) 5
TN - Tunisia 5
TW - Taiwan 5
IL - Israele 4
MT - Malta 4
SA - Arabia Saudita 4
DZ - Algeria 3
EG - Egitto 3
IQ - Iraq 3
LV - Lettonia 3
NO - Norvegia 3
TH - Thailandia 3
UZ - Uzbekistan 3
AE - Emirati Arabi Uniti 2
AZ - Azerbaigian 2
BO - Bolivia 2
BY - Bielorussia 2
DK - Danimarca 2
DO - Repubblica Dominicana 2
KE - Kenya 2
LK - Sri Lanka 2
MU - Mauritius 2
NP - Nepal 2
PT - Portogallo 2
SM - San Marino 2
A2 - ???statistics.table.value.countryCode.A2??? 1
BH - Bahrain 1
CG - Congo 1
CM - Camerun 1
CR - Costa Rica 1
ET - Etiopia 1
FK - Isole Falkland (Malvinas) 1
GE - Georgia 1
GH - Ghana 1
HU - Ungheria 1
KZ - Kazakistan 1
MK - Macedonia 1
ML - Mali 1
NZ - Nuova Zelanda 1
PH - Filippine 1
RS - Serbia 1
UY - Uruguay 1
VE - Venezuela 1
Totale 20.744
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Città #
Southend 1.152
Singapore 1.078
Fairfield 725
Ashburn 714
Chandler 493
Hong Kong 473
Santa Clara 445
Woodbridge 356
Bologna 351
Houston 350
Wilmington 318
Seattle 307
Princeton 272
Ann Arbor 265
Cambridge 244
Jacksonville 237
Milan 233
Beijing 231
Abidjan 214
Hefei 209
Rome 204
Dublin 189
Boardman 178
Lomé 160
Padova 149
Dallas 125
Westminster 121
Los Angeles 120
Nanjing 119
Dong Ket 101
New York 98
Tokyo 81
Ho Chi Minh City 80
Berlin 78
Jinan 74
Florence 67
Buffalo 66
Naples 65
Seoul 65
Shenyang 62
Saint Petersburg 61
Sofia 61
Turin 61
Hanoi 55
Palermo 55
Medford 54
Hebei 53
Bari 52
Redmond 51
Redwood City 51
Changsha 47
Amman 45
Munich 44
Mülheim 41
Redondo Beach 41
San Diego 40
Catania 39
Guangzhou 39
Nanchang 37
Brussels 34
Verona 34
Zhengzhou 34
Tianjin 32
Falls Church 31
Hangzhou 30
Yubileyny 30
Mahé 29
Genoa 28
Shanghai 28
Helsinki 27
Parma 27
Reggio Emilia 25
Dearborn 24
Benevento 23
Jiaxing 23
Norwalk 22
Chicago 21
Des Moines 21
Haikou 21
Bengaluru 19
Frankfurt am Main 19
Jakarta 19
Falkenstein 18
Phoenix 18
São Paulo 18
Taiyuan 18
Warsaw 17
Modena 16
Cesena 15
Olalla 15
Bremen 14
Brescia 14
Livorno 14
London 14
Ningbo 14
San Francisco 14
Stockholm 14
Toronto 14
Brooklyn 13
Harbin 13
Totale 12.670
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Nome #
Farmaci che agiscono sul sistema renina-angiotensina 1.509
Trasportatori di membrana dei farmaci 813
Antidepressivi e antipsicotici 661
Progettazione e sintesi di analoghi rigidi di metoctramina nello studio dei recettori muscarinici 226
Benextramine and derivatives as novel human monoamine oxidases inhibitors: an integrated approach 222
Novel Polyamine–Naphthalene Diimide Conjugates Targeting Histone Deacetylases and DNA for Cancer Phenotype Reprogramming 214
Bovine Serum Amine Oxidase and Polyamine Analogues: Chemical Synthesis and Biological Evaluation Integrated with Molecular Docking and 3-D QSAR Studies 206
Cytotoxicity of methoctramine and methoctramine-related polyamines. 206
Rational Approach to discover multipotent anti-Alzheimer drugs 204
Progettazione e sintesi di poliammine a potenziale attività antitumorale 204
Structure-activity relationships of acetylcholinesterase noncovalent inhibitors based on a polyamine backbone. 3. Effect of replacing the inner polymethylene chain with cyclic moieties 201
Merging memantine and ferulic acid to probe connections between NMDA receptors, oxidative stress and amyloid-β peptide in Alzheimer's disease 198
DESIGN, SYNTHESIS AND BIOLOGICAL EVALUATION OF SUSTITUTED NAPHTHALENE IMIDES AND DIIMIDES AS ANTICANCER AGENT 196
Design, synthesis, and biological evaluation of conformationally restricted rivastigmine analogues 194
Nature-Inspired Multifunctional Ligands: Focusing on Amyloid-Based Molecular Mechanisms of Alzheimer’s Disease 192
Alzheimer's disease: new approaches to drug discovery. 183
Polyamine conjugation of curcumin analogues toward the discovery of mitochondria-directed neuroprotective agents. 182
Progettazione e sintesi di derivati poliamminici per il trattamento della malattia di Alzheimer 175
Pharmacophore Hybridization To Discover Novel Topoisomerase II Poisons with Promising Antiproliferative Activity 174
Structure-activity relationships of novel substituted naphthalene diimides as anticancer agents 173
Exploring the activity of polyamine analogues on polyamine and spermine oxidase: methoctramine, a potent and selective inhibitor of polyamine oxidase 173
Cystamine-tacrine dimer: A new multi-target-directed ligand as potential therapeutic agent for Alzheimer's disease treatment. 168
Multitargeted drugs discovery: Balancing anti-amyloid and anticholinesterase capacity in a single chemical entity 164
Design and synthesis of new multitarget agents for the study of neuroinflammation in Alzheimer's disease 164
LC determination of leuprolide component amino acids in injectable solution by phanquinone pre-column derivatization labelling procedure 163
Galantamine-memantine hybrids for Alzheimer's disease: The influence of linker rigidity in biological activity and pharmacokinetic properties 158
Design, synthesis, and biological evaluation of pirenzepine analogs bearing a 1,2-cyclohexanediamine and a perhydroquinoxaline units in exchange for the piperazine ring as antimuscarinics 155
Lights and shadows of electrophile signaling: Focus on the Nrf2-Keap1 pathway 152
Study of the cytotoxic effects of the new synthetic isothiocyanate CM9 and its fullerene derivative on human T-leukemia cells 151
In vivo characterization of ARN14140, a memantine/galantamine-based multi-target compound for Alzheimer's disease 151
Natural polyamines and synthetic analogs modify the growth and the morphology of Pyrus communis pollen tubes affecting ROS levels and causing cell death 151
Process for preparation of 1,4-benzoquinone-2,5-diamines by reaction of amines with 1,4-benzoquinones bearing leaving groups at the 2- and 5-positions 149
Macrocyclic naphthalene diimides as G-quadruplex binders 149
Memantine Derivatives as Multitarget Agents in Alzheimer’s Disease 149
Design, Synthesis, and biological evaluation of naphtalene diimides derivatives as anticancer agent 147
Synthetic polyamines activating autophagy: Effects on cancer cell death 145
Polyamine Conjugation as a Promising Strategy To Target Amyloid Aggregation in the Framework of Alzheimer’s Disease 144
Design, synthesis, and biological evaluation of substituted naphtalene imides and diimides as anticancer agents 144
Exploiting RNA as a new biomolecular target for synthetic polyamines 143
Multitarget-directed ligands: Innovative chemical probes and therapeutic tools against Alzheimer's disease 143
Double Attack to Oxidative Stress in Neurodegenerative Disorders: MAO-B and Nrf2 as Elected Targets 141
Progress in acetylcholinesterase inhibitors for Alzheimer's disease: an update 141
null 141
Novel Class of Quinone-Bearing Polyamines as Multi-Target-Directed Ligands To Combat Alzheimer's Disease 141
Inhibition of Acetylcholinesterase, Beta-Amyloid Aggregation, and NMDA Receptors in Alzheimer's Disease: A Promising Direction for the Multi-target-Directed Ligands Gold Rush 140
Multi-target Design Strategies in the Context of Alzheimer's Disease: Acetylcholinesterase Inhibition and NMDA Receptor Antagonism as the Driving Forces 139
Preparation, characterization and in vitro evaluation of sterically stabilized liposome containing a naphthalenediimide derivative as anticancer agent 139
Lipocrine, a multipotent drug for the investigation of Alzheimer's disease 138
Inhibition of β-Amyloid Aggregation in Alzheimer's Disease: The Key Role of (Pro)electrophilic Warheads 137
Exploring the effects of isothiocyanates on chemotherapeutic drugs 137
Multi-target-Directed Ligands To Combat Neurodegenerative Diseases 136
An optimized polyamine moiety boosts the potency of human type II topoisomerase poisons as quantified by comparative analysis centered on the clinical candidate F14512 136
Analysis of the muscarinic receptor subtype mediating inhibition of the neurogenic contractions in rabbit isolated vas deferens by a series of polymethylene tetra-amines 135
Beta-secretase monolithic micro-IMER (immobilized enzyme reactor) for on-line HPLC screening of quinone-bearing polyamine inhibitors. 135
Multifunctional Tacrine Derivatives in Alzheimer’s Disease 134
Cytotoxicity of Methoctramine and related Spermine analogues 132
Structure-activity relationships of methoctramine-related polyamines as muscarinic antagonist: Effect of replacing the inner polymethylene chain with cyclic moieties 131
Oxidative stress in Alzheimer’s disease: are we connecting the dots? 131
Polyamine-containing etoposide derivatives as poisons of human type II topoisomerases: Differential effects on topoisomerase IIα and IIβ 131
Synthetic polyamines as potential amine oxidase inhibitors: a preliminary study. 130
Heterocyclic inhibitors of AChE acylation and peripheral sites. 130
Synthesis of Monomeric Derivatives To Probe Memoquin's Bivalent Interactions 130
Cystamine-tacrine dimer: a new multi-target-directed ligand as potential therapeutic agent for Alzheimer’s disease treatment 130
Preliminary evaluation of the cytotoxicity of naphthalene diimide-polyamine conjugates in human cancer cells 130
Benextramine derivatives as probes to target human monoamine oxidases 128
Progress in acetylcholinesterase inhibitors for Alzheimer's disease 126
Multi-Target-Direcetd Ligands as acetylcholinesterase inhibitors and nicotinic modulators for Alzheimer's disease 125
One-molecule-multiple-target strategy: a novel multifunctional molecule designed to block EGF-r and to exert pro-apoptotic effects 124
New quinazoline compounds as non-peptidomimetic BACE-1 inhibitors in the treatment of Alzheimer's disease 124
MTDL design strategy in the context of Alzheimer's disease: from lipocrine to memoquin and beyond 124
In vitro and in vivo evaluation of polymethylene tetraamine derivatives as NMDA receptor channel blockers 124
From dual binding site acetylcholinesterase inhibitors to multi-target-directed ligands (MTDLs): a step forward in the treatment of Alzheimer's disease 123
Polymethylene tetraamine backbone as template for the development of biologically active polyamines 122
Cytotoxicity of methoctramine-related polyamines 121
Structure-Activity Relationships of Acetylcholinesterase Noncovalent Inhibitors Based on a Polyamine Backbone. 4. Futher Investigation on the Inner Spacer. 121
Novel targets for “old” polyamine analogues: monoamine oxidases and benextramine derivatives 120
Methoctramine analogues inhibit responses to capsaicin and protons in rat dorsal root ganglion neurons 119
Discovery of Memoquin, a Multitarget-Directed Ligand (MTDL) for the Treatment of Alzheimer’s Disease 118
Polyamines may modulate both G protein-coupled receptors and G proteins 117
Combined inhibition of the EGFR/AKT pathways by a novel conjugate of quinazoline with isothiocyanate. 117
Methoctramine-related polyamines as antinociceptive agents 116
Novel, Potent, and Druglike Tetrahydroquinazoline Inhibitor That Is Highly Selective for Human Topoisomerase II α over β 116
Methoctramine analogues inhibit responses to capsaicin in DRG neurons and cloned TRPV1 115
Structure-Activity Relationships of New Acetylcholinesterase Noncovalent Inhibitors Based on a Polyamine Backbone 115
Distinct biological responses of metastatic castration resistant prostate cancer cells upon exposure to G-quadruplex interacting naphthalenediimide derivatives 114
Synthetic polyamines: an overview of their multiple biological activities. 113
Rational design of multitarget-directed antioxidants: merging memoquin and lipocrine molecular frameworks 113
Natural-product-inspired modulators of Alzheimer’s disease: focus on amyloid and oxidative stress 113
Novel polyamine analogues: from substrates towards potential inhibitors of monoamine oxidases 113
Discovery of multipotent drugs for the teratment of Alzheimer's disease 112
Polyamines in Drug Discovery: From the Universal Template Approach to the Multitarget-Directed Ligand Design Strategy 112
Inibitori delle fosfodiesterasi 111
Polyamine–Drug Conjugates: Do They Boost Drug Activity? 110
Recent advances in alpha1-adrenoreceptor antagonists as pharmacological tools and therapeutic agents. 109
Quinone-bearing polyamines are AChE inhibitors endowed with multifunctional properties 108
Synthetic polyamines as potential amine oxidases inhibitors: a preliminary study 107
null 107
Lipoic acid, a lead structure for multi-target-directed drugs for neurodegeneration 107
Tacrine Derivatives and Alzheimer's Disease 106
Multi-Target-Directed Drug Design Strategy: Development of new Naphthalene Diimides Bearing Isothiocyanate Functionality As Anticancer Agents 106
Totale 16.817
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Categoria #
all - tutte 57.952
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 3.922
Totale 61.874
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20211.187 0 0 0 0 0 162 85 208 215 134 119 264
2021/20222.626 144 92 163 190 249 180 99 201 141 263 481 423
2022/20232.609 277 321 123 297 150 174 179 148 475 72 233 160
2023/20241.675 70 161 113 122 126 286 95 141 120 126 135 180
2024/20253.828 280 510 398 308 710 224 250 153 98 186 165 546
2025/20263.549 423 640 739 519 870 358 0 0 0 0 0 0
Totale 21.161