CRIS Current Research Information System

TOLOMELLI, ALESSANDRA
 Distribuzione geografica
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Continente #
NA - Nord America 8.867
AS - Asia 8.262
EU - Europa 6.950
AF - Africa 720
Continente sconosciuto - Info sul continente non disponibili 469
SA - Sud America 396
OC - Oceania 14
Totale 25.678
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Nazione #
US - Stati Uniti d'America 8.694
CN - Cina 2.348
IT - Italia 2.304
SG - Singapore 2.095
VN - Vietnam 1.995
GB - Regno Unito 1.335
DE - Germania 770
HK - Hong Kong 499
FR - Francia 425
IN - India 416
SE - Svezia 378
UA - Ucraina 341
RU - Federazione Russa 304
BR - Brasile 265
IE - Irlanda 234
CI - Costa d'Avorio 228
NL - Olanda 211
TG - Togo 201
KR - Corea 176
JP - Giappone 165
FI - Finlandia 143
ZA - Sudafrica 135
BD - Bangladesh 114
BG - Bulgaria 98
CA - Canada 94
SC - Seychelles 83
JO - Giordania 78
EE - Estonia 72
CH - Svizzera 66
BE - Belgio 57
AR - Argentina 54
PH - Filippine 54
ID - Indonesia 52
ES - Italia 39
MX - Messico 37
TR - Turchia 37
TH - Thailandia 33
PK - Pakistan 32
PL - Polonia 32
HR - Croazia 28
TW - Taiwan 26
EC - Ecuador 24
IQ - Iraq 20
NG - Nigeria 20
AT - Austria 19
CL - Cile 18
LB - Libano 18
IR - Iran 17
SA - Arabia Saudita 17
GR - Grecia 14
DZ - Algeria 13
JM - Giamaica 13
AU - Australia 12
CO - Colombia 12
PT - Portogallo 12
RO - Romania 11
UZ - Uzbekistan 11
VE - Venezuela 11
AE - Emirati Arabi Uniti 10
CZ - Repubblica Ceca 10
MA - Marocco 9
CR - Costa Rica 8
EU - Europa 8
DK - Danimarca 7
LT - Lituania 7
HU - Ungheria 6
MY - Malesia 6
IL - Israele 5
KZ - Kazakistan 5
MU - Mauritius 5
NP - Nepal 5
PE - Perù 5
AZ - Azerbaigian 4
BY - Bielorussia 4
EG - Egitto 4
KE - Kenya 4
OM - Oman 4
PR - Porto Rico 4
SK - Slovacchia (Repubblica Slovacca) 4
TN - Tunisia 4
AO - Angola 3
DO - Repubblica Dominicana 3
ET - Etiopia 3
GE - Georgia 3
HN - Honduras 3
KG - Kirghizistan 3
LV - Lettonia 3
RS - Serbia 3
SN - Senegal 3
TT - Trinidad e Tobago 3
UY - Uruguay 3
AL - Albania 2
BA - Bosnia-Erzegovina 2
BN - Brunei Darussalam 2
CY - Cipro 2
GT - Guatemala 2
LY - Libia 2
ML - Mali 2
MO - Macao, regione amministrativa speciale della Cina 2
NI - Nicaragua 2
Totale 25.189
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Città #
Singapore 1.433
Southend 1.092
Ashburn 839
Bologna 706
Chandler 668
Fairfield 635
San Jose 633
Santa Clara 554
Hong Kong 456
Ho Chi Minh City 420
Hanoi 372
Hefei 365
Dong Ket 308
Beijing 302
Wilmington 302
Woodbridge 289
Council Bluffs 278
Seattle 274
Princeton 268
Houston 240
Ann Arbor 234
Jacksonville 232
Dublin 229
Abidjan 228
Cambridge 213
Lomé 201
Dallas 186
Boardman 178
Milan 148
Seoul 148
Lauterbourg 142
Nanjing 133
Tokyo 133
Los Angeles 123
Westminster 115
Helsinki 110
Padova 110
New York 104
Berlin 100
Sofia 98
Amman 77
Shanghai 76
Jinan 67
Buffalo 65
Rome 64
Da Nang 63
Shenyang 63
Haiphong 62
Saint Petersburg 62
Guangzhou 60
Frankfurt am Main 59
Redondo Beach 52
São Paulo 51
Brussels 47
Tianjin 47
Medford 46
Mülheim 42
Bengaluru 40
Hebei 40
Chicago 39
Munich 39
Changsha 38
Bremen 37
Nanchang 36
Hyderabad 34
Des Moines 33
San Diego 33
Forlì 32
Hangzhou 30
Jakarta 30
Naples 30
Phoenix 30
Columbus 29
Turin 29
Chengdu 28
Falkenstein 28
London 28
Mountain View 28
Zhengzhou 28
Paris 26
Cesena 25
Orem 25
Parma 25
Amsterdam 24
Redwood City 24
Verona 24
Atlanta 23
Ferrara 23
Florence 23
Lappeenranta 23
Düsseldorf 22
Jiaxing 22
Johannesburg 22
Mahé 22
Chennai 21
Genoa 21
Biên Hòa 20
Denver 20
Taiyuan 20
Warsaw 20
Totale 15.796
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Nome #
Green Solvent Mixtures for Solid-Phase Peptide Synthesis: A Dimethylformamide-Free Highly Efficient Synthesis of Pharmaceutical-Grade Peptides 380
Replacing piperidine in Solid Phase Peptide Synthesis: effective Fmoc removal by alternative bases 369
Fast Solution-Phase and Liquid-Phase Peptide Syntheses (SolPSS and LPPS) Mediated by Biomimetic Cyclic Propylphosphonic Anhydride (T3P®) 315
Speeding up sustainable solution-phase peptide synthesis using T3P® as a green coupling reagent: methods and challenges 310
Ampicillin sodium: Isolation, identification and synthesis of the last unknown impurity after 60 years of clinical use 303
Targeting integrins αvβ3 and α5β1 with new β-lactam derivatives 297
Can integrin agonists have cards to play against cancer? A literature survey of small molecules integrin activators. 280
Synthesis and Biological Evaluation of Nonpeptide alpha-v-beta-3/alpha-5-beta-1 Integrin Dual Antagonists containing 5,6-Dihydropyridin-2-one Scaffolds 279
Dehydro-beta-proline Containing Alpha-4-beta-1 Integrin Antagonists: Stereochemical Recognition in Ligand-Receptor Interplay 275
Method for the FMOC group cleavage 274
Copper-Free Heck−Cassar−Sonogashira and Suzuki−Miyaura Reactions of Aryl Chlorides: A Sustainable Approach 270
A Nonclassical Stereoselective Semi-Synthesis of Drospirenone via Cross-Metathesis Reaction 267
From green innovations in oligopeptide to oligonucleotide sustainable synthesis: differences and synergies in TIDES chemistry 259
Application of Af4-Multidetection to Liraglutide in Its Formulation: Preserving and Representing Native Aggregation 252
Pharmaceutical green chemistry in peptide synthesis A snapshot on the role of solvents in SPPS 250
Palladium Catalyst Recycling for Heck-Cassar-Sonogashira Cross-Coupling Reactions in Green Solvent/Base Blend 250
Conjecturing about Small-Molecule Agonists and Antagonists of α4β1 Integrin: From Mechanistic Insight to Potential Therapeutic Applications 249
A Sustainable Chemo-Enzymatic Approach to the Synthesis of Liraglutide 249
A novel family of minimal PMRI cyclic peptides as versatile scaffolds for generating new molecular topology. 242
Fast Heck−Cassar−Sonogashira (HCS) Reactions in Green Solvents 241
Process for the preparation of alectinib 239
A convenient synthesis of functionalized isoxazolines and related 5-hydroxy-isoxazolidine-4-carboxylates 230
New Mechanistic Insights into the Copper-Free Heck-Cassar-Sonogashira Cross-Coupling Reaction 229
Fast MacMillan's Imidazolidinone-Catalyzed Enantioselective Synthesis of Polyfunctionalized 4-Isoxazoline Scaffolds 227
A simple route towards peptide analogues containing substituted (S)- or (R)-tryptophans 222
Green Chemistry Impact and Evolution in the Pharma Industry 219
A microwave-enhanced, Lewis acid-catalyzed synthesis of 1,3-dioxolanes and oxazolines from epoxides 215
Practical synthesis of 3-bromo-5,6-dihydropyridin-2-ones via β,γ-unsaturated α-bromo-ketene/imine cycloaddition 214
Steps towards sustainable solid phase peptide synthesis: use and recovery of N-octyl pyrrolidone 214
alpha-Bromo-beta,gamma-unsaturated Ketenes as Valuable Intermediates in the Synthesis of alpha-Amino-beta,gamma-Unsaturated Acids 213
Highly Regio- and Diastereoselective Palladium-Catalyzed Allylic Substitution. Synthesis of 3-(2-aminobutylidene)-4-arylazetidin-2-ones 210
A translation of the twelve principles of green chemistry to guide the development of cross-coupling reactions 209
Integrin Ligands with α/β-Hybrid Peptide Structure: Design, Bioactivity, and Conformational Aspects 209
A novel family of minimalist opioid peptides deprived of the classic pharmacophores 208
Antiangiogenic Effect of Dual/Selective α5β1/αvβ3 Integrin Antagonists Designed on Partially Modified Retro-Inverso Cyclotetrapeptide Mimetics 207
Ac-D-Trp-PheNH2 AND Ac-D-Trp-Phe-GlyNH2 - A NEW CLASS OF UNUSUAL OPIOID PEPTIDES 206
4-Substituted prolines, useful reagents in enantioselective synthesis and conformational restraints in bioactive peptidomimetics design 204
Integrin-mediated adhesive properties of neutrophils are reduced by hyperbaric oxygen therapy in patients with chronic non-healing wound 199
An investigation of the reactivity of MCPBA and alpha-bromoalkenes under traditional or microwave-assisted conditions: Selective formation of epoxides or allylic bromides. 196
Zinc Metal-Promoted Nucleophilic Addition of Azetidin-2-ones to Aldehydes and Nitriles 195
Exploring the reactivity of alkylidene malonamides: synthesis of polyfunctionalized isoxazolidinones, aziridines and oxazolines 194
New isoxazolidinone and 3,4-dehydro-β-proline derivatives as antibacterial agents and MAO-inhibitors: A complex balance between two activities 193
Asymmetric Synthesis of three and four membered ring heterocycles 192
The Inverse Type II β-Turn on D-Trp-Phe, a Pharmacophoric Motif for MOR Agonists. 192
An improved microwave assisted protocol for Yonemitsu-type trimolecular condensation 192
Process for the Synthesis, of Etelcacetide 192
A straightforward route to enantiopure 2-substituted-3,4-dehydro-beta-proline via ring closing metathesis 191
Convenient Synthesis of the Antibiotic Linezolid via an Oxazolidine-2,4-dione Intermediate Derived from the Chiral Building Block Isoserine 189
Synthesis and Biological Evaluation of Azido- and Aziridino-hydroxyl-beta -lactams through Stereo- and Regioselective Epoxide Ring Opening. 188
Stable and Biocompatible Monodispersion of C 60 in Water by Peptides 188
Synthesis and evaluation of the affinity toward mu-opioid receptor of atypical, lipophilic ligands based on the sequence c[Tyr-Pro-Trp-Phe-Gly-]. 187
Synthesis and assay of retro-α4β1 integrin-targeting motifs 186
Topological exploration of cyclic endomorphin-1 analogues, structurally defined models for investigating the bioactive conformation of MOR agonists. 185
Investigation of the Interaction Between the Atypical Agonist c[YpwFG] and MOR 185
Controlled solid phase peptide bond formation using N-carboxyanhydrides and PEG resins in water. 184
Therapeutic Peptides Targeting PPI in Clinical Development: Overview, Mechanism of Action and Perspectives 184
Asymmetric Synthesis of Three and Four Membered Ring Heterocycles - Chapter 1 183
Dehydro-beta-amino Acid Containing Peptides as Promising Sequences for Drug Development 182
One-Pot Two-Step Microwave-Assisted Synthesis of Alkylidene Acetoacetamido Esters, Useful Intermediates for β-Dehydropeptides 182
DESIGN AND SYNTHESIS OF OPIOID PEPTIDE ANALOGUES AND MIMETICS 182
Novel insights into the chemistry of an old medicine: A general degradative pathway for penicillins from a piperacillin/tazobactam stability study 182
Modulation of αvβ3- and α5β1-integrin-mediated adhesion by dehydro-β-amino acids containing peptidomimetics 182
In-peptide synthesis of di-oxazolidinone and dehydroamino acid-oxazolidinone motifs as β-turn inducers 180
Multiple-Layer Chitosan-Based Patches Medicated With LTX-109 Antimicrobial Peptide for Modulated Local Therapy in the Management of Chronic Wounds 179
Opioid Activity Profiles of Oversimplified Peptides Lacking in the Protonable N-Terminus 178
Sustainability in peptide chemistry: current synthesis and purification technologies and future challenges. 176
Unusual Amino Acids: Synthesis and Introduction into Naturally Occurring Peptides and Biologically Active Analogues 174
Solid phase peptide synthesis using side-chain unprotected arginine and histidine with Oxyma Pure/TBEC in green solvents 173
Synthesis of Enantiopure Isosteres of Amino Acids Containing a Quaternary Stereocenter: Experimental and Computational Evaluation of a Novel Class of Atropisomers 173
Highly Diastereoselective Allylic Azide Formation and Isomerization. Synthesis of 3(2'-Amino)-beta-lactams 171
Highly regio- and stereoselective palladium-catalyzed allylic carbonate amination. A practical route to dehydro-beta-amino esters 169
Cyclotetrapeptide Mimics based on a 13-Membered, Partially Modified Retro-Inverso Structure 168
Introduction of hydroxyl- or keto- functionalities into the side chain of azetidin-2-ones via allylic bromide rearrangement, followed by supported reagent substitution 167
NEW PEPTIDOMIMETIC α4β1-INTEGRIN ANTAGONISTS FOR REDUCING INFLAMMATION AND ALLERGIC REACTIONS 167
Peptides and peptidomimetics in medicine, surgery, and biotecnology 166
Synthesis of dehydro-beta-amino esters via highly regioselective amination of allylic carbonates 166
A new generation of opioid peptidomimetics acting as central and/or peripheral analgesics 165
Functionalizations of the C3 side chain of densely substituted azetidin-2-ones 164
Inhibition of cancer cell adhesion by heterochiral Pro-containing RGD mimetics. 164
Cyclopeptide analogs for generating new molecular and 3D diversity 162
Lewis acid induced highly regioselective synthesis of a new class of substituted isoxazolidines 162
Enzymatic Resolution of Ethyl 3-Hydroxy-2(1'substituted-methylidene)-butyrate by Pseudomonas Cepacia Lipase Catalyzed Acetylation 162
Synthesis and Conformational Analysis of Cyclotetrapeptide Mimetic beta-Turn Templates and Validation as 3D Scaffolds 161
Investigation of the GnRH antagonist degarelix isomerization in biological matrices 160
Stereoselective synthesis of a new class of spiro-beta-lactams via epoxide ring opening 160
Stereoselective synthesis of a new class of spiro-beta-lactams via epoxide ring opening 157
Synthesis of chiral non-racemic intermediates and Arg-Gly-Asp mimetics by CaLB-catalyzed resolution 157
Molecular Docking of Opiates and Opioid Peptides, a Tool for the Design of Selective Agonists and Antagonists, and for the Investigation of Atypical Ligand-Receptor Interactions 157
Development of isoxazoline-containing peptidomimetics as dual alpha-v-beta-3 and alpha-5-beta-1 integrin ligands. 156
Process for the synthesis of prostaglandins and intermediates thereof 154
Design and synthesis of Alpha-v-beta-3 and Alpha-5-beta-1 integrin ligands as delivery systems for fluorescent molecules 154
Dehydro-beta-amino acids as scaffolds for the preparation of alpha-v-beta-3, alpha-5-beta-1 and alpha-4-beta-1 integrin ligands 153
Synthesis of Ethyl 5-Hydroxyisoxazolidine-4-carboxylates via Michael Addition/Intramolecular Hemiketalisation 153
DETERMINATION OF THE BIOLOGICALLY ACTIVE STRUCTURE OF THE ATYPICAL MOR-LIGAND c[D-Asp-1-amide-beta-Ala-D-Trp-Phe] AND ANALOGUES BY NMR AND MOLECULAR DOCKING 152
Stereoselective Synthesis of Linear and Cyclic Dehydro-beta-amino Acids for the Preparation of alpha-v-beta-3 and alpha-5-beta-1 Integrin Inhibitors 151
Synthesis of Enantiomerically Pure alpha-v-beta-3 Integrin ligands Based on a 5,6-Dihydropyridin-2-one Scaffold. 150
Two-dimensional UV spectroscopy: A new insight into the structure and dynamics of biomolecules 149
Mastering palladium-catalyzed cross-coupling reactions: the critical role of in situ pre-catalyst reduction design 144
Synthesis and biological evaluation of unprecedented classes of spiro-beta-lactams and azido-beta-lactams as acyl-CoA:cholesterol acyltransferase inhibitors 144
Development and characterization of novel EphB1 receptor antagonists. 144
Totale 20.133
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Categoria #
all - tutte 70.241
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 70.241
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20222.018 0 111 172 110 215 133 80 194 97 128 371 407
2022/20233.170 329 450 172 377 221 253 131 159 612 98 241 127
2023/20241.363 81 135 82 119 142 299 89 121 32 121 67 75
2024/20254.043 180 504 362 279 739 222 354 171 84 253 200 695
2025/20268.493 626 825 778 663 935 443 901 259 1.679 626 423 335
2026/2027594 275 319 0 0 0 0 0 0 0 0 0 0
Totale 25.678