CRIS Current Research Information System

TOLOMELLI, ALESSANDRA
 Distribuzione geografica
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Continente #
NA - Nord America 8.444
AS - Asia 8.197
EU - Europa 6.828
AF - Africa 715
SA - Sud America 388
OC - Oceania 14
Continente sconosciuto - Info sul continente non disponibili 8
Totale 24.594
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Nazione #
US - Stati Uniti d'America 8.309
CN - Cina 2.339
IT - Italia 2.202
SG - Singapore 2.082
VN - Vietnam 1.994
GB - Regno Unito 1.335
DE - Germania 767
HK - Hong Kong 492
FR - Francia 422
IN - India 408
SE - Svezia 377
UA - Ucraina 338
RU - Federazione Russa 304
BR - Brasile 258
IE - Irlanda 233
CI - Costa d'Avorio 228
NL - Olanda 209
TG - Togo 201
KR - Corea 176
JP - Giappone 165
FI - Finlandia 143
ZA - Sudafrica 134
BG - Bulgaria 98
BD - Bangladesh 90
SC - Seychelles 80
JO - Giordania 78
CA - Canada 73
EE - Estonia 72
CH - Svizzera 64
BE - Belgio 57
AR - Argentina 54
PH - Filippine 54
ID - Indonesia 52
ES - Italia 37
TR - Turchia 37
MX - Messico 36
TH - Thailandia 33
PK - Pakistan 32
PL - Polonia 32
HR - Croazia 27
TW - Taiwan 25
EC - Ecuador 24
IQ - Iraq 20
NG - Nigeria 20
AT - Austria 19
CL - Cile 18
LB - Libano 18
IR - Iran 17
SA - Arabia Saudita 17
GR - Grecia 14
DZ - Algeria 13
AU - Australia 12
CO - Colombia 11
PT - Portogallo 11
RO - Romania 11
UZ - Uzbekistan 11
VE - Venezuela 11
AE - Emirati Arabi Uniti 10
CZ - Repubblica Ceca 9
MA - Marocco 9
EU - Europa 8
JM - Giamaica 8
DK - Danimarca 7
LT - Lituania 7
HU - Ungheria 6
IL - Israele 5
MU - Mauritius 5
MY - Malesia 5
NP - Nepal 5
PE - Perù 5
AZ - Azerbaigian 4
BY - Bielorussia 4
EG - Egitto 4
KZ - Kazakistan 4
OM - Oman 4
PR - Porto Rico 4
SK - Slovacchia (Repubblica Slovacca) 4
TN - Tunisia 4
AO - Angola 3
CR - Costa Rica 3
DO - Repubblica Dominicana 3
ET - Etiopia 3
GE - Georgia 3
KE - Kenya 3
KG - Kirghizistan 3
LV - Lettonia 3
RS - Serbia 3
SN - Senegal 3
UY - Uruguay 3
AL - Albania 2
BA - Bosnia-Erzegovina 2
BN - Brunei Darussalam 2
CY - Cipro 2
HN - Honduras 2
LY - Libia 2
ML - Mali 2
MO - Macao, regione amministrativa speciale della Cina 2
NI - Nicaragua 2
NO - Norvegia 2
PY - Paraguay 2
Totale 24.570
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Città #
Singapore 1.420
Southend 1.092
Ashburn 826
Bologna 675
Chandler 668
Fairfield 635
Santa Clara 543
San Jose 523
Hong Kong 451
Ho Chi Minh City 420
Hanoi 371
Hefei 365
Dong Ket 308
Wilmington 302
Beijing 298
Woodbridge 289
Seattle 273
Princeton 268
Houston 237
Ann Arbor 234
Jacksonville 232
Abidjan 228
Dublin 228
Cambridge 213
Lomé 201
Dallas 183
Boardman 177
Council Bluffs 172
Seoul 148
Milan 144
Lauterbourg 142
Nanjing 133
Tokyo 133
Los Angeles 118
Westminster 115
Helsinki 110
Padova 110
Berlin 100
New York 99
Sofia 98
Amman 77
Shanghai 75
Jinan 67
Buffalo 63
Da Nang 63
Shenyang 63
Haiphong 62
Saint Petersburg 62
Rome 61
Guangzhou 60
Frankfurt am Main 59
Redondo Beach 52
São Paulo 49
Brussels 47
Medford 46
Tianjin 46
Mülheim 42
Hebei 40
Chicago 39
Munich 39
Changsha 38
Bremen 37
Bengaluru 36
Nanchang 36
Des Moines 33
Hyderabad 33
San Diego 32
Hangzhou 30
Jakarta 30
Forlì 29
Naples 29
Chengdu 28
Columbus 28
Falkenstein 28
London 28
Mountain View 28
Zhengzhou 28
Turin 27
Phoenix 26
Cesena 25
Orem 25
Parma 25
Amsterdam 24
Paris 24
Redwood City 24
Ferrara 23
Florence 23
Lappeenranta 23
Verona 23
Düsseldorf 22
Jiaxing 22
Johannesburg 22
Mahé 22
Chennai 21
Biên Hòa 20
Taiyuan 20
Warsaw 20
Washington 20
Atlanta 19
Denver 19
Totale 15.444
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Nome #
Replacing piperidine in Solid Phase Peptide Synthesis: effective Fmoc removal by alternative bases 358
Green Solvent Mixtures for Solid-Phase Peptide Synthesis: A Dimethylformamide-Free Highly Efficient Synthesis of Pharmaceutical-Grade Peptides 356
Fast Solution-Phase and Liquid-Phase Peptide Syntheses (SolPSS and LPPS) Mediated by Biomimetic Cyclic Propylphosphonic Anhydride (T3P®) 302
Targeting integrins αvβ3 and α5β1 with new β-lactam derivatives 295
Ampicillin sodium: Isolation, identification and synthesis of the last unknown impurity after 60 years of clinical use 291
Speeding up sustainable solution-phase peptide synthesis using T3P® as a green coupling reagent: methods and challenges 289
Synthesis and Biological Evaluation of Nonpeptide alpha-v-beta-3/alpha-5-beta-1 Integrin Dual Antagonists containing 5,6-Dihydropyridin-2-one Scaffolds 278
Can integrin agonists have cards to play against cancer? A literature survey of small molecules integrin activators. 273
Dehydro-beta-proline Containing Alpha-4-beta-1 Integrin Antagonists: Stereochemical Recognition in Ligand-Receptor Interplay 267
A Nonclassical Stereoselective Semi-Synthesis of Drospirenone via Cross-Metathesis Reaction 260
Method for the FMOC group cleavage 260
From green innovations in oligopeptide to oligonucleotide sustainable synthesis: differences and synergies in TIDES chemistry 257
Copper-Free Heck−Cassar−Sonogashira and Suzuki−Miyaura Reactions of Aryl Chlorides: A Sustainable Approach 254
Application of Af4-Multidetection to Liraglutide in Its Formulation: Preserving and Representing Native Aggregation 249
Conjecturing about Small-Molecule Agonists and Antagonists of α4β1 Integrin: From Mechanistic Insight to Potential Therapeutic Applications 241
Pharmaceutical green chemistry in peptide synthesis A snapshot on the role of solvents in SPPS 240
Fast Heck−Cassar−Sonogashira (HCS) Reactions in Green Solvents 239
A novel family of minimal PMRI cyclic peptides as versatile scaffolds for generating new molecular topology. 238
A Sustainable Chemo-Enzymatic Approach to the Synthesis of Liraglutide 234
Process for the preparation of alectinib 230
A convenient synthesis of functionalized isoxazolines and related 5-hydroxy-isoxazolidine-4-carboxylates 229
New Mechanistic Insights into the Copper-Free Heck-Cassar-Sonogashira Cross-Coupling Reaction 226
Palladium Catalyst Recycling for Heck-Cassar-Sonogashira Cross-Coupling Reactions in Green Solvent/Base Blend 226
Fast MacMillan's Imidazolidinone-Catalyzed Enantioselective Synthesis of Polyfunctionalized 4-Isoxazoline Scaffolds 222
A simple route towards peptide analogues containing substituted (S)- or (R)-tryptophans 220
A microwave-enhanced, Lewis acid-catalyzed synthesis of 1,3-dioxolanes and oxazolines from epoxides 213
Practical synthesis of 3-bromo-5,6-dihydropyridin-2-ones via β,γ-unsaturated α-bromo-ketene/imine cycloaddition 211
alpha-Bromo-beta,gamma-unsaturated Ketenes as Valuable Intermediates in the Synthesis of alpha-Amino-beta,gamma-Unsaturated Acids 210
Highly Regio- and Diastereoselective Palladium-Catalyzed Allylic Substitution. Synthesis of 3-(2-aminobutylidene)-4-arylazetidin-2-ones 207
A novel family of minimalist opioid peptides deprived of the classic pharmacophores 206
Antiangiogenic Effect of Dual/Selective α5β1/αvβ3 Integrin Antagonists Designed on Partially Modified Retro-Inverso Cyclotetrapeptide Mimetics 205
Steps towards sustainable solid phase peptide synthesis: use and recovery of N-octyl pyrrolidone 205
4-Substituted prolines, useful reagents in enantioselective synthesis and conformational restraints in bioactive peptidomimetics design 202
Integrin Ligands with α/β-Hybrid Peptide Structure: Design, Bioactivity, and Conformational Aspects 202
A translation of the twelve principles of green chemistry to guide the development of cross-coupling reactions 201
Ac-D-Trp-PheNH2 AND Ac-D-Trp-Phe-GlyNH2 - A NEW CLASS OF UNUSUAL OPIOID PEPTIDES 200
Integrin-mediated adhesive properties of neutrophils are reduced by hyperbaric oxygen therapy in patients with chronic non-healing wound 197
Green Chemistry Impact and Evolution in the Pharma Industry 197
Zinc Metal-Promoted Nucleophilic Addition of Azetidin-2-ones to Aldehydes and Nitriles 195
Exploring the reactivity of alkylidene malonamides: synthesis of polyfunctionalized isoxazolidinones, aziridines and oxazolines 192
New isoxazolidinone and 3,4-dehydro-β-proline derivatives as antibacterial agents and MAO-inhibitors: A complex balance between two activities 192
Asymmetric Synthesis of three and four membered ring heterocycles 191
A straightforward route to enantiopure 2-substituted-3,4-dehydro-beta-proline via ring closing metathesis 190
An improved microwave assisted protocol for Yonemitsu-type trimolecular condensation 189
Process for the Synthesis, of Etelcacetide 189
Synthesis and Biological Evaluation of Azido- and Aziridino-hydroxyl-beta -lactams through Stereo- and Regioselective Epoxide Ring Opening. 187
An investigation of the reactivity of MCPBA and alpha-bromoalkenes under traditional or microwave-assisted conditions: Selective formation of epoxides or allylic bromides. 187
Synthesis and evaluation of the affinity toward mu-opioid receptor of atypical, lipophilic ligands based on the sequence c[Tyr-Pro-Trp-Phe-Gly-]. 186
Convenient Synthesis of the Antibiotic Linezolid via an Oxazolidine-2,4-dione Intermediate Derived from the Chiral Building Block Isoserine 186
Synthesis and assay of retro-α4β1 integrin-targeting motifs 185
Stable and Biocompatible Monodispersion of C 60 in Water by Peptides 185
Investigation of the Interaction Between the Atypical Agonist c[YpwFG] and MOR 184
Topological exploration of cyclic endomorphin-1 analogues, structurally defined models for investigating the bioactive conformation of MOR agonists. 183
DESIGN AND SYNTHESIS OF OPIOID PEPTIDE ANALOGUES AND MIMETICS 181
Modulation of αvβ3- and α5β1-integrin-mediated adhesion by dehydro-β-amino acids containing peptidomimetics 181
Therapeutic Peptides Targeting PPI in Clinical Development: Overview, Mechanism of Action and Perspectives 181
One-Pot Two-Step Microwave-Assisted Synthesis of Alkylidene Acetoacetamido Esters, Useful Intermediates for β-Dehydropeptides 180
Asymmetric Synthesis of Three and Four Membered Ring Heterocycles - Chapter 1 179
The Inverse Type II β-Turn on D-Trp-Phe, a Pharmacophoric Motif for MOR Agonists. 179
Multiple-Layer Chitosan-Based Patches Medicated With LTX-109 Antimicrobial Peptide for Modulated Local Therapy in the Management of Chronic Wounds 178
Dehydro-beta-amino Acid Containing Peptides as Promising Sequences for Drug Development 178
Opioid Activity Profiles of Oversimplified Peptides Lacking in the Protonable N-Terminus 177
In-peptide synthesis of di-oxazolidinone and dehydroamino acid-oxazolidinone motifs as β-turn inducers 176
Novel insights into the chemistry of an old medicine: A general degradative pathway for penicillins from a piperacillin/tazobactam stability study 174
Highly Diastereoselective Allylic Azide Formation and Isomerization. Synthesis of 3(2'-Amino)-beta-lactams 171
Controlled solid phase peptide bond formation using N-carboxyanhydrides and PEG resins in water. 171
Sustainability in peptide chemistry: current synthesis and purification technologies and future challenges. 170
Solid phase peptide synthesis using side-chain unprotected arginine and histidine with Oxyma Pure/TBEC in green solvents 169
Synthesis of Enantiopure Isosteres of Amino Acids Containing a Quaternary Stereocenter: Experimental and Computational Evaluation of a Novel Class of Atropisomers 169
Unusual Amino Acids: Synthesis and Introduction into Naturally Occurring Peptides and Biologically Active Analogues 168
Highly regio- and stereoselective palladium-catalyzed allylic carbonate amination. A practical route to dehydro-beta-amino esters 168
Cyclotetrapeptide Mimics based on a 13-Membered, Partially Modified Retro-Inverso Structure 167
Introduction of hydroxyl- or keto- functionalities into the side chain of azetidin-2-ones via allylic bromide rearrangement, followed by supported reagent substitution 166
NEW PEPTIDOMIMETIC α4β1-INTEGRIN ANTAGONISTS FOR REDUCING INFLAMMATION AND ALLERGIC REACTIONS 166
Peptides and peptidomimetics in medicine, surgery, and biotecnology 165
Functionalizations of the C3 side chain of densely substituted azetidin-2-ones 163
A new generation of opioid peptidomimetics acting as central and/or peripheral analgesics 163
Synthesis of dehydro-beta-amino esters via highly regioselective amination of allylic carbonates 162
Lewis acid induced highly regioselective synthesis of a new class of substituted isoxazolidines 162
Enzymatic Resolution of Ethyl 3-Hydroxy-2(1'substituted-methylidene)-butyrate by Pseudomonas Cepacia Lipase Catalyzed Acetylation 162
Inhibition of cancer cell adhesion by heterochiral Pro-containing RGD mimetics. 161
Cyclopeptide analogs for generating new molecular and 3D diversity 161
Investigation of the GnRH antagonist degarelix isomerization in biological matrices 160
Stereoselective synthesis of a new class of spiro-beta-lactams via epoxide ring opening 159
Synthesis and Conformational Analysis of Cyclotetrapeptide Mimetic beta-Turn Templates and Validation as 3D Scaffolds 158
Development of isoxazoline-containing peptidomimetics as dual alpha-v-beta-3 and alpha-5-beta-1 integrin ligands. 156
Molecular Docking of Opiates and Opioid Peptides, a Tool for the Design of Selective Agonists and Antagonists, and for the Investigation of Atypical Ligand-Receptor Interactions 155
Stereoselective synthesis of a new class of spiro-beta-lactams via epoxide ring opening 154
Synthesis of chiral non-racemic intermediates and Arg-Gly-Asp mimetics by CaLB-catalyzed resolution 154
Synthesis of Ethyl 5-Hydroxyisoxazolidine-4-carboxylates via Michael Addition/Intramolecular Hemiketalisation 152
DETERMINATION OF THE BIOLOGICALLY ACTIVE STRUCTURE OF THE ATYPICAL MOR-LIGAND c[D-Asp-1-amide-beta-Ala-D-Trp-Phe] AND ANALOGUES BY NMR AND MOLECULAR DOCKING 151
Design and synthesis of Alpha-v-beta-3 and Alpha-5-beta-1 integrin ligands as delivery systems for fluorescent molecules 151
Synthesis of Enantiomerically Pure alpha-v-beta-3 Integrin ligands Based on a 5,6-Dihydropyridin-2-one Scaffold. 150
Stereoselective Synthesis of Linear and Cyclic Dehydro-beta-amino Acids for the Preparation of alpha-v-beta-3 and alpha-5-beta-1 Integrin Inhibitors 149
Dehydro-beta-amino acids as scaffolds for the preparation of alpha-v-beta-3, alpha-5-beta-1 and alpha-4-beta-1 integrin ligands 149
Process for the synthesis of prostaglandins and intermediates thereof 149
Two-dimensional UV spectroscopy: A new insight into the structure and dynamics of biomolecules 148
Synthesis and biological evaluation of unprecedented classes of spiro-beta-lactams and azido-beta-lactams as acyl-CoA:cholesterol acyltransferase inhibitors 143
Short peptidomimetics containing heterocyclic scaffolds as alpha-v-beta-3 integrins ligands. 142
Synthesis of four-membered ring spiro-beta -lactams by epoxide ring-opening. 141
Totale 19.680
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Categoria #
all - tutte 67.222
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 67.222
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021478 0 0 0 0 0 0 0 0 0 0 0 478
2021/20222.341 323 111 172 110 215 133 80 194 97 128 371 407
2022/20233.170 329 450 172 377 221 253 131 159 612 98 241 127
2023/20241.363 81 135 82 119 142 299 89 121 32 121 67 75
2024/20254.043 180 504 362 279 739 222 354 171 84 253 200 695
2025/20268.463 626 825 778 663 935 443 901 259 1.679 626 423 305
Totale 25.054