CRIS Current Research Information System

TOLOMELLI, ALESSANDRA
 Distribuzione geografica
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Continente #
NA - Nord America 6.116
EU - Europa 5.161
AS - Asia 2.614
AF - Africa 505
SA - Sud America 24
Continente sconosciuto - Info sul continente non disponibili 8
OC - Oceania 8
Totale 14.436
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Nazione #
US - Stati Uniti d'America 6.094
IT - Italia 1.533
GB - Regno Unito 1.242
CN - Cina 974
SG - Singapore 651
DE - Germania 607
VN - Vietnam 478
SE - Svezia 366
UA - Ucraina 324
IN - India 300
IE - Irlanda 224
TG - Togo 201
FR - Francia 199
RU - Federazione Russa 187
CI - Costa d'Avorio 135
ZA - Sudafrica 107
BG - Bulgaria 98
JO - Giordania 77
EE - Estonia 70
FI - Finlandia 68
CH - Svizzera 60
BE - Belgio 46
JP - Giappone 30
NL - Olanda 30
HR - Croazia 25
SC - Seychelles 25
CA - Canada 20
ID - Indonesia 19
NG - Nigeria 18
IR - Iran 17
PL - Polonia 17
LB - Libano 15
ES - Italia 13
BR - Brasile 11
AT - Austria 10
DZ - Algeria 10
GR - Grecia 10
PK - Pakistan 9
RO - Romania 9
CL - Cile 8
EU - Europa 8
TR - Turchia 8
AU - Australia 7
CZ - Repubblica Ceca 7
AR - Argentina 5
HK - Hong Kong 5
BD - Bangladesh 4
KR - Corea 4
MU - Mauritius 4
AE - Emirati Arabi Uniti 3
EG - Egitto 3
PT - Portogallo 3
SA - Arabia Saudita 3
SK - Slovacchia (Repubblica Slovacca) 3
CY - Cipro 2
DK - Danimarca 2
IL - Israele 2
KZ - Kazakistan 2
LV - Lettonia 2
MO - Macao, regione amministrativa speciale della Cina 2
NO - Norvegia 2
OM - Oman 2
UZ - Uzbekistan 2
HU - Ungheria 1
LA - Repubblica Popolare Democratica del Laos 1
LI - Liechtenstein 1
LU - Lussemburgo 1
MD - Moldavia 1
MW - Malawi 1
MX - Messico 1
MY - Malesia 1
NZ - Nuova Zelanda 1
PH - Filippine 1
PR - Porto Rico 1
TH - Thailandia 1
TN - Tunisia 1
TW - Taiwan 1
Totale 14.436
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Città #
Southend 1.092
Chandler 668
Fairfield 635
Singapore 575
Santa Clara 510
Ashburn 490
Bologna 468
Dong Ket 308
Wilmington 300
Woodbridge 289
Princeton 268
Seattle 265
Ann Arbor 234
Houston 232
Jacksonville 229
Dublin 220
Cambridge 206
Lomé 201
Boardman 154
Abidjan 135
Nanjing 127
Westminster 115
Padova 105
Sofia 98
Berlin 97
Milan 87
Amman 77
Beijing 71
Jinan 66
Saint Petersburg 62
Shenyang 61
Helsinki 53
Medford 46
New York 44
Shanghai 43
Mülheim 42
Brussels 41
Hebei 40
Bremen 37
Nanchang 33
San Diego 32
Des Moines 30
Rome 30
Changsha 29
Forlì 29
Guangzhou 29
Tianjin 29
Mountain View 28
Hyderabad 26
Cesena 25
Redwood City 24
Turin 23
Mahé 22
Parma 21
Ferrara 20
Hangzhou 20
Jiaxing 20
Los Angeles 20
Zhengzhou 20
Haikou 19
Taiyuan 19
Tokyo 19
Forlimpopoli 18
Jakarta 18
Taizhou 18
Abeokuta 17
Fremont 17
Naples 17
Redmond 16
Zurich 16
Lappeenranta 15
Moscow 15
Norwalk 15
Verona 15
Florence 14
Ningbo 14
Olalla 14
Pune 14
Washington 14
London 13
Boydton 12
Chicago 12
Paris 12
Stienta 12
Bühl 11
Kunming 11
Lausanne 11
Salerno 11
Dearborn 10
Durban 10
Imola 10
Mumbai 10
Ravenna 10
San Venanzo 10
Warsaw 10
Bern 9
Duncan 9
Falkenstein 9
Falls Church 9
Ferrara di Monte Baldo 9
Totale 9.845
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Nome #
Can integrin agonists have cards to play against cancer? A literature survey of small molecules integrin activators. 208
Green Solvent Mixtures for Solid-Phase Peptide Synthesis: A Dimethylformamide-Free Highly Efficient Synthesis of Pharmaceutical-Grade Peptides 196
Targeting integrins αvβ3 and α5β1 with new β-lactam derivatives 187
Dehydro-beta-proline Containing Alpha-4-beta-1 Integrin Antagonists: Stereochemical Recognition in Ligand-Receptor Interplay 186
A novel family of minimal PMRI cyclic peptides as versatile scaffolds for generating new molecular topology. 182
Replacing piperidine in Solid Phase Peptide Synthesis: effective Fmoc removal by alternative bases 181
A simple route towards peptide analogues containing substituted (S)- or (R)-tryptophans 172
Pharmaceutical green chemistry in peptide synthesis A snapshot on the role of solvents in SPPS 170
A novel family of minimalist opioid peptides deprived of the classic pharmacophores 168
A convenient synthesis of functionalized isoxazolines and related 5-hydroxy-isoxazolidine-4-carboxylates 167
A Nonclassical Stereoselective Semi-Synthesis of Drospirenone via Cross-Metathesis Reaction 167
Ampicillin sodium: Isolation, identification and synthesis of the last unknown impurity after 60 years of clinical use 161
Method for the FMOC group cleavage 160
4-Substituted prolines, useful reagents in enantioselective synthesis and conformational restraints in bioactive peptidomimetics design 154
A microwave-enhanced, Lewis acid-catalyzed synthesis of 1,3-dioxolanes and oxazolines from epoxides 153
Fast Heck−Cassar−Sonogashira (HCS) Reactions in Green Solvents 153
Process for the preparation of alectinib 148
Ac-D-Trp-PheNH2 AND Ac-D-Trp-Phe-GlyNH2 - A NEW CLASS OF UNUSUAL OPIOID PEPTIDES 147
New isoxazolidinone and 3,4-dehydro-β-proline derivatives as antibacterial agents and MAO-inhibitors: A complex balance between two activities 146
Practical synthesis of 3-bromo-5,6-dihydropyridin-2-ones via β,γ-unsaturated α-bromo-ketene/imine cycloaddition 142
Antiangiogenic Effect of Dual/Selective α5β1/αvβ3 Integrin Antagonists Designed on Partially Modified Retro-Inverso Cyclotetrapeptide Mimetics 142
Palladium Catalyst Recycling for Heck-Cassar-Sonogashira Cross-Coupling Reactions in Green Solvent/Base Blend 142
A straightforward route to enantiopure 2-substituted-3,4-dehydro-beta-proline via ring closing metathesis 139
Highly Regio- and Diastereoselective Palladium-Catalyzed Allylic Substitution. Synthesis of 3-(2-aminobutylidene)-4-arylazetidin-2-ones 137
An improved microwave assisted protocol for Yonemitsu-type trimolecular condensation 137
An investigation of the reactivity of MCPBA and alpha-bromoalkenes under traditional or microwave-assisted conditions: Selective formation of epoxides or allylic bromides. 135
alpha-Bromo-beta,gamma-unsaturated Ketenes as Valuable Intermediates in the Synthesis of alpha-Amino-beta,gamma-Unsaturated Acids 134
Asymmetric Synthesis of three and four membered ring heterocycles 133
Convenient Synthesis of the Antibiotic Linezolid via an Oxazolidine-2,4-dione Intermediate Derived from the Chiral Building Block Isoserine 132
DESIGN AND SYNTHESIS OF OPIOID PEPTIDE ANALOGUES AND MIMETICS 131
Integrin Ligands with α/β-Hybrid Peptide Structure: Design, Bioactivity, and Conformational Aspects 131
Zinc Metal-Promoted Nucleophilic Addition of Azetidin-2-ones to Aldehydes and Nitriles 128
Exploring the reactivity of alkylidene malonamides: synthesis of polyfunctionalized isoxazolidinones, aziridines and oxazolines 128
One-Pot Two-Step Microwave-Assisted Synthesis of Alkylidene Acetoacetamido Esters, Useful Intermediates for β-Dehydropeptides 125
Opioid Activity Profiles of Oversimplified Peptides Lacking in the Protonable N-Terminus 123
Dehydro-beta-amino Acid Containing Peptides as Promising Sequences for Drug Development 122
Steps towards sustainable solid phase peptide synthesis: use and recovery of N-octyl pyrrolidone 122
Synthesis and Biological Evaluation of Azido- and Aziridino-hydroxyl-beta -lactams through Stereo- and Regioselective Epoxide Ring Opening. 121
The Inverse Type II β-Turn on D-Trp-Phe, a Pharmacophoric Motif for MOR Agonists. 120
A new generation of opioid peptidomimetics acting as central and/or peripheral analgesics 120
Enzymatic Resolution of Ethyl 3-Hydroxy-2(1'substituted-methylidene)-butyrate by Pseudomonas Cepacia Lipase Catalyzed Acetylation 120
Stable and Biocompatible Monodispersion of C 60 in Water by Peptides 120
Synthesis and evaluation of the affinity toward mu-opioid receptor of atypical, lipophilic ligands based on the sequence c[Tyr-Pro-Trp-Phe-Gly-]. 119
Inhibition of cancer cell adhesion by heterochiral Pro-containing RGD mimetics. 119
Modulation of αvβ3- and α5β1-integrin-mediated adhesion by dehydro-β-amino acids containing peptidomimetics 117
Highly regio- and stereoselective palladium-catalyzed allylic carbonate amination. A practical route to dehydro-beta-amino esters 116
Topological exploration of cyclic endomorphin-1 analogues, structurally defined models for investigating the bioactive conformation of MOR agonists. 115
Asymmetric Synthesis of Three and Four Membered Ring Heterocycles - Chapter 1 115
Cyclotetrapeptide Mimics based on a 13-Membered, Partially Modified Retro-Inverso Structure 115
Molecular Docking of Opiates and Opioid Peptides, a Tool for the Design of Selective Agonists and Antagonists, and for the Investigation of Atypical Ligand-Receptor Interactions 115
Synthesis and assay of retro-α4β1 integrin-targeting motifs 114
Synthesis and Biological Evaluation of Nonpeptide alpha-v-beta-3/alpha-5-beta-1 Integrin Dual Antagonists containing 5,6-Dihydropyridin-2-one Scaffolds 113
Synthesis of dehydro-beta-amino esters via highly regioselective amination of allylic carbonates 113
In-peptide synthesis of di-oxazolidinone and dehydroamino acid-oxazolidinone motifs as β-turn inducers 113
Synthesis of Enantiopure Isosteres of Amino Acids Containing a Quaternary Stereocenter: Experimental and Computational Evaluation of a Novel Class of Atropisomers 113
Lewis acid induced highly regioselective synthesis of a new class of substituted isoxazolidines 113
Highly Diastereoselective Allylic Azide Formation and Isomerization. Synthesis of 3(2'-Amino)-beta-lactams 111
Development of isoxazoline-containing peptidomimetics as dual alpha-v-beta-3 and alpha-5-beta-1 integrin ligands. 111
Controlled solid phase peptide bond formation using N-carboxyanhydrides and PEG resins in water. 111
A translation of the twelve principles of green chemistry to guide the development of cross-coupling reactions 111
Unusual Amino Acids: Synthesis and Introduction into Naturally Occurring Peptides and Biologically Active Analogues 110
Investigation of the Interaction Between the Atypical Agonist c[YpwFG] and MOR 110
Green Chemistry Impact and Evolution in the Pharma Industry 110
Cyclopeptide analogs for generating new molecular and 3D diversity 109
Integrin-mediated adhesive properties of neutrophils are reduced by hyperbaric oxygen therapy in patients with chronic non-healing wound 109
Two-dimensional UV spectroscopy: A new insight into the structure and dynamics of biomolecules 106
Synthesis of chiral non-racemic intermediates and Arg-Gly-Asp mimetics by CaLB-catalyzed resolution 104
Peptides and peptidomimetics in medicine, surgery, and biotecnology 103
Dehydro-beta-amino acids as scaffolds for the preparation of alpha-v-beta-3, alpha-5-beta-1 and alpha-4-beta-1 integrin ligands 103
NEW PEPTIDOMIMETIC α4β1-INTEGRIN ANTAGONISTS FOR REDUCING INFLAMMATION AND ALLERGIC REACTIONS 103
Synthesis of Ethyl 5-Hydroxyisoxazolidine-4-carboxylates via Michael Addition/Intramolecular Hemiketalisation 103
Novel insights into the chemistry of an old medicine: A general degradative pathway for penicillins from a piperacillin/tazobactam stability study 102
Stereoselective synthesis of a new class of spiro-beta-lactams via epoxide ring opening 101
Atypical mu-opioid agonists: reconsideration of the requisites for receptor activation 99
Stereoselective synthesis of a new class of spiro-beta-lactams via epoxide ring opening 98
Synthesis and biological evaluation of unprecedented classes of spiro-beta-lactams and azido-beta-lactams as acyl-CoA:cholesterol acyltransferase inhibitors 98
DETERMINATION OF THE BIOLOGICALLY ACTIVE STRUCTURE OF THE ATYPICAL MOR-LIGAND c[D-Asp-1-amide-beta-Ala-D-Trp-Phe] AND ANALOGUES BY NMR AND MOLECULAR DOCKING 98
Short peptidomimetics containing heterocyclic scaffolds as alpha-v-beta-3 integrins ligands. 98
Functionalizations of the C3 side chain of densely substituted azetidin-2-ones 97
Design and synthesis of integrin ligands as «molecular shuttles» for drugs and fluorescent molecules delivery 96
Process for the Synthesis, of Etelcacetide 96
Synthesis of Enantiomerically Pure alpha-v-beta-3 Integrin ligands Based on a 5,6-Dihydropyridin-2-one Scaffold. 94
null 93
Biologically active analogues of naturally occurring peptides 93
Design and synthesis of Alpha-v-beta-3 and Alpha-5-beta-1 integrin ligands as delivery systems for fluorescent molecules 93
Synthesis and Conformational Analysis of Cyclotetrapeptide Mimetic beta-Turn Templates and Validation as 3D Scaffolds 93
Interactions between atypical opioid agonists and MOR 93
Therapeutic Peptides Targeting PPI in Clinical Development: Overview, Mechanism of Action and Perspectives 93
Stereoselective Synthesis of Linear and Cyclic Dehydro-beta-amino Acids for the Preparation of alpha-v-beta-3 and alpha-5-beta-1 Integrin Inhibitors 92
Synthesis of alpha/beta dipeptides containing linear or cyclic alpha-dehydro-beta-amino acids as scaffolds for bioactive compounds 92
Alkylidene malonamides and acetacetamides as intermediates for the preparation of constrained dipeptide mimetics. 91
Synthesis of Constrained Peptidomimetics Containing 2-Oxo-1,3-oxazolidine-4-carboxylic Acids 91
Speeding up sustainable solution-phase peptide synthesis using T3P® as a green coupling reagent: methods and challenges 89
Introduction of hydroxyl- or keto- functionalities into the side chain of azetidin-2-ones via allylic bromide rearrangement, followed by supported reagent substitution 88
Process for the synthesis of prostaglandins and intermediates thereof 88
null 88
Synthesis and Biological Evaluation of Nonpeptide alpha-v-beta-3/alpha-5-beta-1 Integrin Dual Antagonists 87
Development and characterization of novel EphB1 receptor antagonists. 87
Development and characterization of novel EphB1 receptor antagonists. 87
Synthesis of four-membered ring spiro-beta -lactams by epoxide ring-opening. 86
Totale 12.115
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Categoria #
all - tutte 39.573
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 39.573
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201.752 0 0 0 0 0 216 303 381 366 217 79 190
2020/20211.878 358 127 80 135 44 90 50 106 199 92 119 478
2021/20222.341 323 111 172 110 215 133 80 194 97 128 371 407
2022/20233.170 329 450 172 377 221 253 131 159 612 98 241 127
2023/20241.363 81 135 82 119 142 299 89 121 32 121 67 75
2024/20252.261 180 504 362 279 739 197 0 0 0 0 0 0
Totale 14.809