CRIS Current Research Information System

TOLOMELLI, ALESSANDRA
 Distribuzione geografica
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Continente #
NA - Nord America 7.092
EU - Europa 6.229
AS - Asia 6.057
AF - Africa 674
SA - Sud America 319
OC - Oceania 12
Continente sconosciuto - Info sul continente non disponibili 8
Totale 20.391
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Nazione #
US - Stati Uniti d'America 7.021
CN - Cina 2.040
IT - Italia 1.916
SG - Singapore 1.821
GB - Regno Unito 1.311
VN - Vietnam 880
DE - Germania 742
HK - Hong Kong 439
SE - Svezia 375
IN - India 355
UA - Ucraina 331
RU - Federazione Russa 299
FR - Francia 277
IE - Irlanda 231
CI - Costa d'Avorio 227
BR - Brasile 211
TG - Togo 201
NL - Olanda 182
KR - Corea 152
ZA - Sudafrica 114
JP - Giappone 112
FI - Finlandia 107
BG - Bulgaria 98
SC - Seychelles 80
JO - Giordania 77
EE - Estonia 71
CH - Svizzera 62
BE - Belgio 54
AR - Argentina 52
ID - Indonesia 44
CA - Canada 43
ES - Italia 29
PL - Polonia 29
HR - Croazia 26
EC - Ecuador 23
MX - Messico 21
NG - Nigeria 19
AT - Austria 18
TR - Turchia 18
IR - Iran 17
LB - Libano 17
CL - Cile 15
PK - Pakistan 14
DZ - Algeria 12
GR - Grecia 12
BD - Bangladesh 11
AU - Australia 10
RO - Romania 10
CZ - Repubblica Ceca 9
PT - Portogallo 9
CO - Colombia 8
EU - Europa 8
AE - Emirati Arabi Uniti 7
LT - Lituania 7
TW - Taiwan 7
HU - Ungheria 6
UZ - Uzbekistan 6
IL - Israele 5
MA - Marocco 5
DK - Danimarca 4
EG - Egitto 4
MU - Mauritius 4
VE - Venezuela 4
KZ - Kazakistan 3
NP - Nepal 3
PE - Perù 3
SA - Arabia Saudita 3
SK - Slovacchia (Repubblica Slovacca) 3
AL - Albania 2
AZ - Azerbaigian 2
BA - Bosnia-Erzegovina 2
BN - Brunei Darussalam 2
CY - Cipro 2
DO - Repubblica Dominicana 2
GE - Georgia 2
IQ - Iraq 2
KG - Kirghizistan 2
LV - Lettonia 2
MO - Macao, regione amministrativa speciale della Cina 2
NO - Norvegia 2
OM - Oman 2
PH - Filippine 2
PR - Porto Rico 2
PY - Paraguay 2
SN - Senegal 2
TH - Thailandia 2
TN - Tunisia 2
AO - Angola 1
BO - Bolivia 1
DM - Dominica 1
HN - Honduras 1
KE - Kenya 1
KH - Cambogia 1
KI - Kiribati 1
KW - Kuwait 1
LA - Repubblica Popolare Democratica del Laos 1
LI - Liechtenstein 1
LU - Lussemburgo 1
MD - Moldavia 1
ML - Mali 1
Totale 20.385
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Città #
Singapore 1.216
Southend 1.092
Ashburn 729
Chandler 668
Fairfield 635
Bologna 591
Santa Clara 523
Hong Kong 429
Hefei 360
Dong Ket 308
Wilmington 300
Woodbridge 289
Beijing 274
Seattle 271
Princeton 268
Houston 235
Ann Arbor 234
Jacksonville 229
Abidjan 227
Dublin 227
Cambridge 213
Lomé 201
Dallas 163
Boardman 157
Seoul 146
Ho Chi Minh City 133
Nanjing 131
Milan 120
Westminster 115
Padova 110
Hanoi 107
Berlin 98
Sofia 98
Los Angeles 95
Tokyo 95
Amman 77
Helsinki 75
Jinan 67
New York 64
Saint Petersburg 62
Shenyang 62
Shanghai 58
Buffalo 56
Redondo Beach 52
Brussels 46
Guangzhou 46
Medford 46
Frankfurt am Main 44
Mülheim 42
Rome 42
Hebei 40
Tianjin 40
Munich 39
Bremen 37
Changsha 35
Nanchang 34
Bengaluru 33
San Diego 32
Des Moines 31
São Paulo 31
Forlì 29
Falkenstein 28
Jakarta 28
Mountain View 28
Chengdu 27
Chicago 27
Zhengzhou 27
Hyderabad 26
Turin 26
Cesena 25
Hangzhou 25
Paris 24
Redwood City 24
Ferrara 23
London 23
Düsseldorf 22
Lappeenranta 22
Mahé 22
Naples 22
Phoenix 22
Florence 21
Parma 21
Jiaxing 20
Taiyuan 20
Council Bluffs 19
Haikou 19
Warsaw 19
Forlimpopoli 18
Haiphong 18
Moscow 18
Taizhou 18
Zurich 18
Abeokuta 17
Fremont 17
Verona 17
Yubileyny 17
Ningbo 16
Redmond 16
Modena 15
Norwalk 15
Totale 13.137
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Nome #
Green Solvent Mixtures for Solid-Phase Peptide Synthesis: A Dimethylformamide-Free Highly Efficient Synthesis of Pharmaceutical-Grade Peptides 283
Replacing piperidine in Solid Phase Peptide Synthesis: effective Fmoc removal by alternative bases 278
Targeting integrins αvβ3 and α5β1 with new β-lactam derivatives 254
Synthesis and Biological Evaluation of Nonpeptide alpha-v-beta-3/alpha-5-beta-1 Integrin Dual Antagonists containing 5,6-Dihydropyridin-2-one Scaffolds 249
Can integrin agonists have cards to play against cancer? A literature survey of small molecules integrin activators. 244
Speeding up sustainable solution-phase peptide synthesis using T3P® as a green coupling reagent: methods and challenges 242
Fast Solution-Phase and Liquid-Phase Peptide Syntheses (SolPSS and LPPS) Mediated by Biomimetic Cyclic Propylphosphonic Anhydride (T3P®) 241
Dehydro-beta-proline Containing Alpha-4-beta-1 Integrin Antagonists: Stereochemical Recognition in Ligand-Receptor Interplay 227
Ampicillin sodium: Isolation, identification and synthesis of the last unknown impurity after 60 years of clinical use 223
A novel family of minimal PMRI cyclic peptides as versatile scaffolds for generating new molecular topology. 219
Method for the FMOC group cleavage 214
Pharmaceutical green chemistry in peptide synthesis A snapshot on the role of solvents in SPPS 213
Copper-Free Heck−Cassar−Sonogashira and Suzuki−Miyaura Reactions of Aryl Chlorides: A Sustainable Approach 210
Application of Af4-Multidetection to Liraglutide in Its Formulation: Preserving and Representing Native Aggregation 209
A Nonclassical Stereoselective Semi-Synthesis of Drospirenone via Cross-Metathesis Reaction 206
Process for the preparation of alectinib 202
A simple route towards peptide analogues containing substituted (S)- or (R)-tryptophans 198
Fast Heck−Cassar−Sonogashira (HCS) Reactions in Green Solvents 197
A convenient synthesis of functionalized isoxazolines and related 5-hydroxy-isoxazolidine-4-carboxylates 195
Practical synthesis of 3-bromo-5,6-dihydropyridin-2-ones via β,γ-unsaturated α-bromo-ketene/imine cycloaddition 194
A novel family of minimalist opioid peptides deprived of the classic pharmacophores 190
From green innovations in oligopeptide to oligonucleotide sustainable synthesis: differences and synergies in TIDES chemistry 189
A microwave-enhanced, Lewis acid-catalyzed synthesis of 1,3-dioxolanes and oxazolines from epoxides 188
Palladium Catalyst Recycling for Heck-Cassar-Sonogashira Cross-Coupling Reactions in Green Solvent/Base Blend 186
Ac-D-Trp-PheNH2 AND Ac-D-Trp-Phe-GlyNH2 - A NEW CLASS OF UNUSUAL OPIOID PEPTIDES 182
4-Substituted prolines, useful reagents in enantioselective synthesis and conformational restraints in bioactive peptidomimetics design 182
alpha-Bromo-beta,gamma-unsaturated Ketenes as Valuable Intermediates in the Synthesis of alpha-Amino-beta,gamma-Unsaturated Acids 181
Highly Regio- and Diastereoselective Palladium-Catalyzed Allylic Substitution. Synthesis of 3-(2-aminobutylidene)-4-arylazetidin-2-ones 181
Conjecturing about Small-Molecule Agonists and Antagonists of α4β1 Integrin: From Mechanistic Insight to Potential Therapeutic Applications 179
Antiangiogenic Effect of Dual/Selective α5β1/αvβ3 Integrin Antagonists Designed on Partially Modified Retro-Inverso Cyclotetrapeptide Mimetics 179
New Mechanistic Insights into the Copper-Free Heck-Cassar-Sonogashira Cross-Coupling Reaction 177
Fast MacMillan's Imidazolidinone-Catalyzed Enantioselective Synthesis of Polyfunctionalized 4-Isoxazoline Scaffolds 175
Steps towards sustainable solid phase peptide synthesis: use and recovery of N-octyl pyrrolidone 172
New isoxazolidinone and 3,4-dehydro-β-proline derivatives as antibacterial agents and MAO-inhibitors: A complex balance between two activities 171
Synthesis and evaluation of the affinity toward mu-opioid receptor of atypical, lipophilic ligands based on the sequence c[Tyr-Pro-Trp-Phe-Gly-]. 170
An improved microwave assisted protocol for Yonemitsu-type trimolecular condensation 170
Exploring the reactivity of alkylidene malonamides: synthesis of polyfunctionalized isoxazolidinones, aziridines and oxazolines 170
Zinc Metal-Promoted Nucleophilic Addition of Azetidin-2-ones to Aldehydes and Nitriles 169
Convenient Synthesis of the Antibiotic Linezolid via an Oxazolidine-2,4-dione Intermediate Derived from the Chiral Building Block Isoserine 167
A straightforward route to enantiopure 2-substituted-3,4-dehydro-beta-proline via ring closing metathesis 166
Asymmetric Synthesis of three and four membered ring heterocycles 165
Integrin Ligands with α/β-Hybrid Peptide Structure: Design, Bioactivity, and Conformational Aspects 165
An investigation of the reactivity of MCPBA and alpha-bromoalkenes under traditional or microwave-assisted conditions: Selective formation of epoxides or allylic bromides. 162
A translation of the twelve principles of green chemistry to guide the development of cross-coupling reactions 162
A Sustainable Chemo-Enzymatic Approach to the Synthesis of Liraglutide 160
Synthesis and Biological Evaluation of Azido- and Aziridino-hydroxyl-beta -lactams through Stereo- and Regioselective Epoxide Ring Opening. 159
Topological exploration of cyclic endomorphin-1 analogues, structurally defined models for investigating the bioactive conformation of MOR agonists. 159
Opioid Activity Profiles of Oversimplified Peptides Lacking in the Protonable N-Terminus 157
DESIGN AND SYNTHESIS OF OPIOID PEPTIDE ANALOGUES AND MIMETICS 157
Dehydro-beta-amino Acid Containing Peptides as Promising Sequences for Drug Development 156
The Inverse Type II β-Turn on D-Trp-Phe, a Pharmacophoric Motif for MOR Agonists. 156
Unusual Amino Acids: Synthesis and Introduction into Naturally Occurring Peptides and Biologically Active Analogues 155
Asymmetric Synthesis of Three and Four Membered Ring Heterocycles - Chapter 1 155
Integrin-mediated adhesive properties of neutrophils are reduced by hyperbaric oxygen therapy in patients with chronic non-healing wound 155
Highly Diastereoselective Allylic Azide Formation and Isomerization. Synthesis of 3(2'-Amino)-beta-lactams 154
One-Pot Two-Step Microwave-Assisted Synthesis of Alkylidene Acetoacetamido Esters, Useful Intermediates for β-Dehydropeptides 154
Stable and Biocompatible Monodispersion of C 60 in Water by Peptides 154
Synthesis and assay of retro-α4β1 integrin-targeting motifs 153
Modulation of αvβ3- and α5β1-integrin-mediated adhesion by dehydro-β-amino acids containing peptidomimetics 153
Investigation of the Interaction Between the Atypical Agonist c[YpwFG] and MOR 152
Green Chemistry Impact and Evolution in the Pharma Industry 152
Inhibition of cancer cell adhesion by heterochiral Pro-containing RGD mimetics. 148
Highly regio- and stereoselective palladium-catalyzed allylic carbonate amination. A practical route to dehydro-beta-amino esters 147
A new generation of opioid peptidomimetics acting as central and/or peripheral analgesics 147
Peptides and peptidomimetics in medicine, surgery, and biotecnology 144
Synthesis of dehydro-beta-amino esters via highly regioselective amination of allylic carbonates 144
Cyclotetrapeptide Mimics based on a 13-Membered, Partially Modified Retro-Inverso Structure 144
Lewis acid induced highly regioselective synthesis of a new class of substituted isoxazolidines 144
Controlled solid phase peptide bond formation using N-carboxyanhydrides and PEG resins in water. 144
Stereoselective synthesis of a new class of spiro-beta-lactams via epoxide ring opening 143
Synthesis of Enantiopure Isosteres of Amino Acids Containing a Quaternary Stereocenter: Experimental and Computational Evaluation of a Novel Class of Atropisomers 143
In-peptide synthesis of di-oxazolidinone and dehydroamino acid-oxazolidinone motifs as β-turn inducers 142
Enzymatic Resolution of Ethyl 3-Hydroxy-2(1'substituted-methylidene)-butyrate by Pseudomonas Cepacia Lipase Catalyzed Acetylation 142
Cyclopeptide analogs for generating new molecular and 3D diversity 140
Molecular Docking of Opiates and Opioid Peptides, a Tool for the Design of Selective Agonists and Antagonists, and for the Investigation of Atypical Ligand-Receptor Interactions 139
Stereoselective synthesis of a new class of spiro-beta-lactams via epoxide ring opening 137
Functionalizations of the C3 side chain of densely substituted azetidin-2-ones 136
Development of isoxazoline-containing peptidomimetics as dual alpha-v-beta-3 and alpha-5-beta-1 integrin ligands. 136
Therapeutic Peptides Targeting PPI in Clinical Development: Overview, Mechanism of Action and Perspectives 135
Investigation of the GnRH antagonist degarelix isomerization in biological matrices 134
Introduction of hydroxyl- or keto- functionalities into the side chain of azetidin-2-ones via allylic bromide rearrangement, followed by supported reagent substitution 134
Novel insights into the chemistry of an old medicine: A general degradative pathway for penicillins from a piperacillin/tazobactam stability study 134
NEW PEPTIDOMIMETIC α4β1-INTEGRIN ANTAGONISTS FOR REDUCING INFLAMMATION AND ALLERGIC REACTIONS 132
Synthesis of Ethyl 5-Hydroxyisoxazolidine-4-carboxylates via Michael Addition/Intramolecular Hemiketalisation 132
DETERMINATION OF THE BIOLOGICALLY ACTIVE STRUCTURE OF THE ATYPICAL MOR-LIGAND c[D-Asp-1-amide-beta-Ala-D-Trp-Phe] AND ANALOGUES BY NMR AND MOLECULAR DOCKING 132
Dehydro-beta-amino acids as scaffolds for the preparation of alpha-v-beta-3, alpha-5-beta-1 and alpha-4-beta-1 integrin ligands 131
Synthesis of chiral non-racemic intermediates and Arg-Gly-Asp mimetics by CaLB-catalyzed resolution 131
Synthesis and Conformational Analysis of Cyclotetrapeptide Mimetic beta-Turn Templates and Validation as 3D Scaffolds 131
Process for the Synthesis, of Etelcacetide 128
Two-dimensional UV spectroscopy: A new insight into the structure and dynamics of biomolecules 127
Stereoselective Synthesis of Linear and Cyclic Dehydro-beta-amino Acids for the Preparation of alpha-v-beta-3 and alpha-5-beta-1 Integrin Inhibitors 126
Design and synthesis of Alpha-v-beta-3 and Alpha-5-beta-1 integrin ligands as delivery systems for fluorescent molecules 126
Synthesis of Enantiomerically Pure alpha-v-beta-3 Integrin ligands Based on a 5,6-Dihydropyridin-2-one Scaffold. 124
Synthesis of four-membered ring spiro-beta -lactams by epoxide ring-opening. 122
Process for the synthesis of prostaglandins and intermediates thereof 122
Multiple-Layer Chitosan-Based Patches Medicated With LTX-109 Antimicrobial Peptide for Modulated Local Therapy in the Management of Chronic Wounds 121
Synthesis of alpha/beta dipeptides containing linear or cyclic alpha-dehydro-beta-amino acids as scaffolds for bioactive compounds 121
Synthesis and Biological Evaluation of Nonpeptide alpha-v-beta-3/alpha-5-beta-1 Integrin Dual Antagonists 120
Short peptidomimetics containing heterocyclic scaffolds as alpha-v-beta-3 integrins ligands. 120
Sustainability in peptide chemistry: current synthesis and purification technologies and future challenges. 120
Totale 16.560
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Categoria #
all - tutte 58.127
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 58.127
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20211.134 0 0 0 0 0 90 50 106 199 92 119 478
2021/20222.341 323 111 172 110 215 133 80 194 97 128 371 407
2022/20233.170 329 450 172 377 221 253 131 159 612 98 241 127
2023/20241.363 81 135 82 119 142 299 89 121 32 121 67 75
2024/20254.043 180 504 362 279 739 222 354 171 84 253 200 695
2025/20264.212 626 825 778 663 935 385 0 0 0 0 0 0
Totale 20.803