CRIS Current Research Information System

TOLOMELLI, ALESSANDRA
 Distribuzione geografica
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Continente #
AS - Asia 8.016
NA - Nord America 7.899
EU - Europa 6.624
AF - Africa 710
SA - Sud America 371
OC - Oceania 14
Continente sconosciuto - Info sul continente non disponibili 8
Totale 23.642
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Nazione #
US - Stati Uniti d'America 7.804
CN - Cina 2.310
IT - Italia 2.052
SG - Singapore 2.043
VN - Vietnam 1.973
GB - Regno Unito 1.313
DE - Germania 763
HK - Hong Kong 479
FR - Francia 415
IN - India 401
SE - Svezia 375
UA - Ucraina 338
RU - Federazione Russa 302
BR - Brasile 241
IE - Irlanda 231
CI - Costa d'Avorio 227
NL - Olanda 203
TG - Togo 199
KR - Corea 176
JP - Giappone 162
FI - Finlandia 143
ZA - Sudafrica 133
BG - Bulgaria 97
SC - Seychelles 80
JO - Giordania 77
EE - Estonia 70
CH - Svizzera 63
BE - Belgio 57
CA - Canada 56
AR - Argentina 54
PH - Filippine 54
ID - Indonesia 48
TR - Turchia 36
ES - Italia 35
TH - Thailandia 33
BD - Bangladesh 32
PL - Polonia 32
PK - Pakistan 29
HR - Croazia 27
MX - Messico 26
EC - Ecuador 24
TW - Taiwan 24
IQ - Iraq 20
NG - Nigeria 20
AT - Austria 19
CL - Cile 18
LB - Libano 18
IR - Iran 17
SA - Arabia Saudita 17
GR - Grecia 14
DZ - Algeria 13
AU - Australia 12
CO - Colombia 11
PT - Portogallo 11
UZ - Uzbekistan 11
VE - Venezuela 11
AE - Emirati Arabi Uniti 10
CZ - Repubblica Ceca 9
MA - Marocco 9
RO - Romania 9
EU - Europa 8
DK - Danimarca 7
LT - Lituania 7
HU - Ungheria 6
IL - Israele 5
MU - Mauritius 5
MY - Malesia 5
PE - Perù 5
AZ - Azerbaigian 4
BY - Bielorussia 4
EG - Egitto 4
KZ - Kazakistan 4
NP - Nepal 4
OM - Oman 4
SK - Slovacchia (Repubblica Slovacca) 4
TN - Tunisia 4
AO - Angola 3
DO - Repubblica Dominicana 3
GE - Georgia 3
JM - Giamaica 3
KE - Kenya 3
KG - Kirghizistan 3
LV - Lettonia 3
SN - Senegal 3
UY - Uruguay 3
AL - Albania 2
BA - Bosnia-Erzegovina 2
BN - Brunei Darussalam 2
CY - Cipro 2
ET - Etiopia 2
LY - Libia 2
ML - Mali 2
MO - Macao, regione amministrativa speciale della Cina 2
NO - Norvegia 2
PR - Porto Rico 2
PY - Paraguay 2
QA - Qatar 2
RS - Serbia 2
SI - Slovenia 2
BO - Bolivia 1
Totale 23.622
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Città #
Singapore 1.391
Southend 1.080
Ashburn 777
Chandler 661
Bologna 636
Fairfield 634
Santa Clara 523
Hong Kong 438
San Jose 429
Ho Chi Minh City 417
Hanoi 369
Hefei 365
Dong Ket 308
Wilmington 301
Woodbridge 289
Beijing 288
Seattle 272
Princeton 266
Houston 237
Ann Arbor 233
Jacksonville 231
Abidjan 227
Dublin 226
Cambridge 213
Lomé 199
Dallas 169
Boardman 157
Seoul 148
Lauterbourg 141
Nanjing 132
Tokyo 131
Milan 124
Westminster 114
Los Angeles 111
Helsinki 110
Padova 109
Council Bluffs 101
Berlin 99
Sofia 97
New York 78
Amman 76
Shanghai 73
Jinan 67
Da Nang 62
Haiphong 62
Saint Petersburg 62
Shenyang 62
Guangzhou 60
Frankfurt am Main 59
Buffalo 58
Rome 57
Redondo Beach 52
Brussels 47
Medford 45
Tianjin 45
Mülheim 42
Hebei 40
Munich 39
Changsha 38
Bremen 37
São Paulo 37
Nanchang 35
Bengaluru 34
Chicago 33
Des Moines 33
Hyderabad 33
San Diego 32
Jakarta 30
Forlì 29
Hangzhou 29
Chengdu 28
Falkenstein 28
Zhengzhou 28
Mountain View 27
Turin 26
Cesena 25
Amsterdam 24
Columbus 24
London 24
Orem 24
Paris 24
Redwood City 24
Ferrara 23
Florence 23
Lappeenranta 23
Parma 23
Düsseldorf 22
Jiaxing 22
Johannesburg 22
Mahé 22
Naples 22
Verona 22
Phoenix 21
Biên Hòa 20
Warsaw 20
Chennai 19
Haikou 19
Shenzhen 19
Taiyuan 19
Taizhou 19
Totale 14.925
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Nome #
Green Solvent Mixtures for Solid-Phase Peptide Synthesis: A Dimethylformamide-Free Highly Efficient Synthesis of Pharmaceutical-Grade Peptides 340
Replacing piperidine in Solid Phase Peptide Synthesis: effective Fmoc removal by alternative bases 330
Targeting integrins αvβ3 and α5β1 with new β-lactam derivatives 292
Fast Solution-Phase and Liquid-Phase Peptide Syntheses (SolPSS and LPPS) Mediated by Biomimetic Cyclic Propylphosphonic Anhydride (T3P®) 291
Speeding up sustainable solution-phase peptide synthesis using T3P® as a green coupling reagent: methods and challenges 281
Ampicillin sodium: Isolation, identification and synthesis of the last unknown impurity after 60 years of clinical use 275
Synthesis and Biological Evaluation of Nonpeptide alpha-v-beta-3/alpha-5-beta-1 Integrin Dual Antagonists containing 5,6-Dihydropyridin-2-one Scaffolds 268
Can integrin agonists have cards to play against cancer? A literature survey of small molecules integrin activators. 268
Dehydro-beta-proline Containing Alpha-4-beta-1 Integrin Antagonists: Stereochemical Recognition in Ligand-Receptor Interplay 263
Method for the FMOC group cleavage 253
Copper-Free Heck−Cassar−Sonogashira and Suzuki−Miyaura Reactions of Aryl Chlorides: A Sustainable Approach 246
From green innovations in oligopeptide to oligonucleotide sustainable synthesis: differences and synergies in TIDES chemistry 246
Application of Af4-Multidetection to Liraglutide in Its Formulation: Preserving and Representing Native Aggregation 245
A Nonclassical Stereoselective Semi-Synthesis of Drospirenone via Cross-Metathesis Reaction 242
Pharmaceutical green chemistry in peptide synthesis A snapshot on the role of solvents in SPPS 236
A novel family of minimal PMRI cyclic peptides as versatile scaffolds for generating new molecular topology. 235
Fast Heck−Cassar−Sonogashira (HCS) Reactions in Green Solvents 231
Process for the preparation of alectinib 228
A convenient synthesis of functionalized isoxazolines and related 5-hydroxy-isoxazolidine-4-carboxylates 221
A simple route towards peptide analogues containing substituted (S)- or (R)-tryptophans 217
Fast MacMillan's Imidazolidinone-Catalyzed Enantioselective Synthesis of Polyfunctionalized 4-Isoxazoline Scaffolds 216
Conjecturing about Small-Molecule Agonists and Antagonists of α4β1 Integrin: From Mechanistic Insight to Potential Therapeutic Applications 214
Palladium Catalyst Recycling for Heck-Cassar-Sonogashira Cross-Coupling Reactions in Green Solvent/Base Blend 214
New Mechanistic Insights into the Copper-Free Heck-Cassar-Sonogashira Cross-Coupling Reaction 211
Practical synthesis of 3-bromo-5,6-dihydropyridin-2-ones via β,γ-unsaturated α-bromo-ketene/imine cycloaddition 210
alpha-Bromo-beta,gamma-unsaturated Ketenes as Valuable Intermediates in the Synthesis of alpha-Amino-beta,gamma-Unsaturated Acids 207
A Sustainable Chemo-Enzymatic Approach to the Synthesis of Liraglutide 205
A novel family of minimalist opioid peptides deprived of the classic pharmacophores 203
A microwave-enhanced, Lewis acid-catalyzed synthesis of 1,3-dioxolanes and oxazolines from epoxides 203
Highly Regio- and Diastereoselective Palladium-Catalyzed Allylic Substitution. Synthesis of 3-(2-aminobutylidene)-4-arylazetidin-2-ones 202
Steps towards sustainable solid phase peptide synthesis: use and recovery of N-octyl pyrrolidone 201
4-Substituted prolines, useful reagents in enantioselective synthesis and conformational restraints in bioactive peptidomimetics design 200
A translation of the twelve principles of green chemistry to guide the development of cross-coupling reactions 198
Integrin Ligands with α/β-Hybrid Peptide Structure: Design, Bioactivity, and Conformational Aspects 198
Antiangiogenic Effect of Dual/Selective α5β1/αvβ3 Integrin Antagonists Designed on Partially Modified Retro-Inverso Cyclotetrapeptide Mimetics 197
Ac-D-Trp-PheNH2 AND Ac-D-Trp-Phe-GlyNH2 - A NEW CLASS OF UNUSUAL OPIOID PEPTIDES 193
Zinc Metal-Promoted Nucleophilic Addition of Azetidin-2-ones to Aldehydes and Nitriles 191
Integrin-mediated adhesive properties of neutrophils are reduced by hyperbaric oxygen therapy in patients with chronic non-healing wound 191
A straightforward route to enantiopure 2-substituted-3,4-dehydro-beta-proline via ring closing metathesis 190
Exploring the reactivity of alkylidene malonamides: synthesis of polyfunctionalized isoxazolidinones, aziridines and oxazolines 190
Green Chemistry Impact and Evolution in the Pharma Industry 190
New isoxazolidinone and 3,4-dehydro-β-proline derivatives as antibacterial agents and MAO-inhibitors: A complex balance between two activities 189
An improved microwave assisted protocol for Yonemitsu-type trimolecular condensation 187
Asymmetric Synthesis of three and four membered ring heterocycles 186
An investigation of the reactivity of MCPBA and alpha-bromoalkenes under traditional or microwave-assisted conditions: Selective formation of epoxides or allylic bromides. 186
Synthesis and evaluation of the affinity toward mu-opioid receptor of atypical, lipophilic ligands based on the sequence c[Tyr-Pro-Trp-Phe-Gly-]. 184
Synthesis and Biological Evaluation of Azido- and Aziridino-hydroxyl-beta -lactams through Stereo- and Regioselective Epoxide Ring Opening. 182
Convenient Synthesis of the Antibiotic Linezolid via an Oxazolidine-2,4-dione Intermediate Derived from the Chiral Building Block Isoserine 182
Synthesis and assay of retro-α4β1 integrin-targeting motifs 181
Stable and Biocompatible Monodispersion of C 60 in Water by Peptides 181
Topological exploration of cyclic endomorphin-1 analogues, structurally defined models for investigating the bioactive conformation of MOR agonists. 179
Investigation of the Interaction Between the Atypical Agonist c[YpwFG] and MOR 179
DESIGN AND SYNTHESIS OF OPIOID PEPTIDE ANALOGUES AND MIMETICS 179
Modulation of αvβ3- and α5β1-integrin-mediated adhesion by dehydro-β-amino acids containing peptidomimetics 179
Asymmetric Synthesis of Three and Four Membered Ring Heterocycles - Chapter 1 176
The Inverse Type II β-Turn on D-Trp-Phe, a Pharmacophoric Motif for MOR Agonists. 176
One-Pot Two-Step Microwave-Assisted Synthesis of Alkylidene Acetoacetamido Esters, Useful Intermediates for β-Dehydropeptides 176
Dehydro-beta-amino Acid Containing Peptides as Promising Sequences for Drug Development 173
Therapeutic Peptides Targeting PPI in Clinical Development: Overview, Mechanism of Action and Perspectives 173
Opioid Activity Profiles of Oversimplified Peptides Lacking in the Protonable N-Terminus 171
Process for the Synthesis, of Etelcacetide 170
In-peptide synthesis of di-oxazolidinone and dehydroamino acid-oxazolidinone motifs as β-turn inducers 169
Synthesis of Enantiopure Isosteres of Amino Acids Containing a Quaternary Stereocenter: Experimental and Computational Evaluation of a Novel Class of Atropisomers 168
Controlled solid phase peptide bond formation using N-carboxyanhydrides and PEG resins in water. 168
Highly Diastereoselective Allylic Azide Formation and Isomerization. Synthesis of 3(2'-Amino)-beta-lactams 167
Highly regio- and stereoselective palladium-catalyzed allylic carbonate amination. A practical route to dehydro-beta-amino esters 166
Unusual Amino Acids: Synthesis and Introduction into Naturally Occurring Peptides and Biologically Active Analogues 165
Cyclotetrapeptide Mimics based on a 13-Membered, Partially Modified Retro-Inverso Structure 165
Novel insights into the chemistry of an old medicine: A general degradative pathway for penicillins from a piperacillin/tazobactam stability study 165
Multiple-Layer Chitosan-Based Patches Medicated With LTX-109 Antimicrobial Peptide for Modulated Local Therapy in the Management of Chronic Wounds 164
Sustainability in peptide chemistry: current synthesis and purification technologies and future challenges. 164
NEW PEPTIDOMIMETIC α4β1-INTEGRIN ANTAGONISTS FOR REDUCING INFLAMMATION AND ALLERGIC REACTIONS 163
A new generation of opioid peptidomimetics acting as central and/or peripheral analgesics 162
Peptides and peptidomimetics in medicine, surgery, and biotecnology 161
Inhibition of cancer cell adhesion by heterochiral Pro-containing RGD mimetics. 161
Lewis acid induced highly regioselective synthesis of a new class of substituted isoxazolidines 161
Enzymatic Resolution of Ethyl 3-Hydroxy-2(1'substituted-methylidene)-butyrate by Pseudomonas Cepacia Lipase Catalyzed Acetylation 161
Cyclopeptide analogs for generating new molecular and 3D diversity 160
Functionalizations of the C3 side chain of densely substituted azetidin-2-ones 159
Introduction of hydroxyl- or keto- functionalities into the side chain of azetidin-2-ones via allylic bromide rearrangement, followed by supported reagent substitution 159
Investigation of the GnRH antagonist degarelix isomerization in biological matrices 158
Synthesis of dehydro-beta-amino esters via highly regioselective amination of allylic carbonates 158
Synthesis and Conformational Analysis of Cyclotetrapeptide Mimetic beta-Turn Templates and Validation as 3D Scaffolds 158
Development of isoxazoline-containing peptidomimetics as dual alpha-v-beta-3 and alpha-5-beta-1 integrin ligands. 156
Stereoselective synthesis of a new class of spiro-beta-lactams via epoxide ring opening 155
Solid phase peptide synthesis using side-chain unprotected arginine and histidine with Oxyma Pure/TBEC in green solvents 154
Molecular Docking of Opiates and Opioid Peptides, a Tool for the Design of Selective Agonists and Antagonists, and for the Investigation of Atypical Ligand-Receptor Interactions 152
Synthesis of chiral non-racemic intermediates and Arg-Gly-Asp mimetics by CaLB-catalyzed resolution 151
Stereoselective synthesis of a new class of spiro-beta-lactams via epoxide ring opening 150
Dehydro-beta-amino acids as scaffolds for the preparation of alpha-v-beta-3, alpha-5-beta-1 and alpha-4-beta-1 integrin ligands 149
Synthesis of Ethyl 5-Hydroxyisoxazolidine-4-carboxylates via Michael Addition/Intramolecular Hemiketalisation 149
Stereoselective Synthesis of Linear and Cyclic Dehydro-beta-amino Acids for the Preparation of alpha-v-beta-3 and alpha-5-beta-1 Integrin Inhibitors 148
Process for the synthesis of prostaglandins and intermediates thereof 148
Design and synthesis of Alpha-v-beta-3 and Alpha-5-beta-1 integrin ligands as delivery systems for fluorescent molecules 148
DETERMINATION OF THE BIOLOGICALLY ACTIVE STRUCTURE OF THE ATYPICAL MOR-LIGAND c[D-Asp-1-amide-beta-Ala-D-Trp-Phe] AND ANALOGUES BY NMR AND MOLECULAR DOCKING 147
Two-dimensional UV spectroscopy: A new insight into the structure and dynamics of biomolecules 146
Synthesis of Enantiomerically Pure alpha-v-beta-3 Integrin ligands Based on a 5,6-Dihydropyridin-2-one Scaffold. 145
Synthesis and biological evaluation of unprecedented classes of spiro-beta-lactams and azido-beta-lactams as acyl-CoA:cholesterol acyltransferase inhibitors 140
Development and characterization of novel EphB1 receptor antagonists. 140
Synthesis of alpha/beta dipeptides containing linear or cyclic alpha-dehydro-beta-amino acids as scaffolds for bioactive compounds 140
Totale 19.121
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Categoria #
all - tutte 63.005
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 63.005
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021674 0 0 0 0 0 0 0 0 0 92 119 463
2021/20222.329 322 110 171 110 214 132 80 192 97 127 371 403
2022/20233.145 327 445 171 374 219 252 131 158 605 97 241 125
2023/20241.358 81 134 82 117 141 298 89 121 32 121 67 75
2024/20254.020 180 496 360 278 732 222 353 171 84 251 200 693
2025/20267.603 624 823 776 662 930 439 896 259 1.672 522 0 0
Totale 24.090