This review covers our recent advances in the synthesis of unusual amino acids in optically pure form, and their introduction into naturally occurring peptides with specific biological properties, or into modified bioactive peptides, aiming to obtain analogues displaying enhanced performances in term of activity, bioavailability and resistance to enzymatic hydrolysis.
G.Cardillo, L. Gentilucci, A. Tolomelli (2006). Unusual Amino Acids: Synthesis and Introduction into Naturally Occurring Peptides and Biologically Active Analogues. MINI-REVIEWS IN MEDICINAL CHEMISTRY, 6, 293-304 [10.2174/138955706776073394].
Unusual Amino Acids: Synthesis and Introduction into Naturally Occurring Peptides and Biologically Active Analogues
CARDILLO, GIULIANA;GENTILUCCI, LUCA;TOLOMELLI, ALESSANDRA
2006
Abstract
This review covers our recent advances in the synthesis of unusual amino acids in optically pure form, and their introduction into naturally occurring peptides with specific biological properties, or into modified bioactive peptides, aiming to obtain analogues displaying enhanced performances in term of activity, bioavailability and resistance to enzymatic hydrolysis.File in questo prodotto:
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