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A multivariate non-parametric approach for estimating probability of exceeding the local natural background level of arsenic in the aquifers of Calabria region (Southern Italy)

The concept of natural background level (NBL) aims at distinguishing the natural and anthropogenic contributions to concentrations of specific contaminants, as groundwater management and protection tools. This is usually defined as a unique value at a regional scale, even when the hydrogeological and geochemical features of a certain territory are far from homogeneous. The concentration of target contaminants is affected by multiple hydrogeochemical processes. This is the case of arsenic in t...

Sensory–Motor Loop Adaptation in Boolean Network Robots

Recent technological advances have made it possible to produce tiny robots equipped with simple sensors and effectors. Micro-robots are particularly suitable for scenarios such as exploration of hostile environments, and emergency intervention, e.g., in areas subject to earthquakes or fires. A crucial desirable feature of such a robot is the capability of adapting to the specific environment in which it has to operate. Given the limited computational capabilities of a micro-robot, this proper...

Softwarized and containerized microservices-based network management analysis with MSN

Microservice architecture is a service-oriented paradigm that enables the decomposition of cumbersome monolithic-based software systems. Using microservice design principles, it is possible to develop flexible, scalable, reusable, and loosely coupled software that could be containerized and deployed in a distributed edge/cloud environment. The flexible deployment of microservices in an edge environment increases system performance in terms due to dynamic service function placement and chainin...

Numerical investigation of thermal discharge to coastal areas: A case study in South Italy

Coupled wave – 3D-hydrodynamics model runs are performed to investigate thermal discharge release to coastal areas by means of including nearshore effects of wave-current dynamics. The study area comprises the vicinity of a power plant at Cerano, in South Italy, where cooling industrial waters are released to the sea. The implemented model is calibrated by using temperature measurements and sensitivity analyses are carried out for various relevant drivers and input parameters. Afterwards, the...

The Reporting of a Disproportionality Analysis for Drug Safety Signal Detection Using Individual Case Safety Reports in PharmacoVigilance (READUS-PV): Development and Statement

Background and aim: Disproportionality analyses using reports of suspected adverse drug reactions are the most commonly used quantitative methods for detecting safety signals in pharmacovigilance. However, their methods and results are generally poorly reported in published articles and existing guidelines do not capture the specific features of disproportionality analyses. We here describe the development of a guideline (REporting of A Disproportionality analysis for drUg Safety signal detec...

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