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Variation of subclinical psychosis across 16 sites in Europe and Brazil: findings from the multi-national EU-GEI study

Background Incidence of first-episode psychosis (FEP) varies substantially across geographic regions. Phenotypes of subclinical psychosis (SP), such as psychotic-like experiences (PLEs) and schizotypy, present several similarities with psychosis. We aimed to examine whether SP measures varied across different sites and whether this variation was comparable with FEP incidence within the same areas. We further examined contribution of environmental and genetic factors to SP. Methods We used dat...

HCC recurrence in liver transplants treated with hypothermic oxygenated machine perfusion: An international matched cohort study

Background & Aims: Liver transplantation (LT) for hepatocellular carcinoma (HCC) is performed worldwide, with 5-year survival rates of approximately 70%. However, post-transplant HCC recurrence occurs in 15-20% of recipients. We aimed to evaluate, for the first time, long-term recurrence-free survival in a large international cohort of patients undergoing LT for HCC using grafts treated with hypothermic oxygenated machine perfusion (HOPE). Methods: This observational post hoc analysis of ...

Comparing the Last Interglacial (MIS 5e) with the present interglacial period (MIS 1) using a multidimensional functional diversity analysis: The marine molluscs from Santa Maria Island (Azores Archipelago, central Atlantic) as a case study

Marine fossil records hold outstanding importance for ecological, evolutionary and biogeographicalstudies. Santa Maria Island in the Azores Archipelago (central Atlantic) features a remarkable marine fossil record spanningfrom the Pliocene to recent times. This record includes late Pleistocene outcrops with fossiliferous deposits dated from thelast interglacial period (MIS 5e). In this study, we describe a newly discovered MIS 5e outcrop (Ponta do Cedro) andinvestigate its marine mollusc asse...

Interplay Between Childhood Maltreatment, Subclinical Post-Traumatic Stress Symptoms, and IQ: Findings From the EU-GEI Multicentre Case–Control Study

Introduction: Evidence suggests that childhood maltreatment affects cognitive performance in both patients with psychosis and community controls. However, the interplay between childhood maltreatment, post-traumatic stress symptoms (PTSS), and intelligence has not been investigated. This study investigated the relationship between childhood maltreatment, subclinical PTSS, and intelligence among patients with first-episode psychosis (FEP) and community controls. Methods: Patients with FEP (N =...

Coastal flood impacts and lost ecosystem services along Europe’s outermost regions and overseas countries and territories

Climate change is expected to result in rising seas, exacerbating coastal floods and erosion. Remote islands are projected to be among the most challenged regions, due to their geographic isolation and fragile economies. While, Small Island Developing States have been attracting the attention of scientists and policy makers, Europe’s Outermost Regions (ORs) and Overseas Countries and Territories (OCTs) remain poorly studied in terms of their impacts from Sea Level Rise (SLR). Here we carry ou...

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