CRIS Current Research Information System

PORCELLI, ANNA MARIA
 Distribuzione geografica
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Continente #
NA - Nord America 4.798
EU - Europa 4.269
AS - Asia 1.294
AF - Africa 249
SA - Sud America 12
OC - Oceania 11
Continente sconosciuto - Info sul continente non disponibili 3
Totale 10.636
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Nazione #
US - Stati Uniti d'America 4.775
IT - Italia 1.387
GB - Regno Unito 868
SE - Svezia 480
CN - Cina 441
DE - Germania 397
VN - Vietnam 300
SG - Singapore 257
UA - Ucraina 216
IN - India 177
IE - Irlanda 153
FR - Francia 151
RU - Federazione Russa 140
TG - Togo 100
CH - Svizzera 95
ZA - Sudafrica 67
EE - Estonia 63
CI - Costa d'Avorio 60
BG - Bulgaria 44
JO - Giordania 43
ES - Italia 42
NL - Olanda 40
FI - Finlandia 31
BE - Belgio 28
HR - Croazia 23
PT - Portogallo 19
SK - Slovacchia (Repubblica Slovacca) 18
AT - Austria 17
GR - Grecia 17
SC - Seychelles 15
CA - Canada 14
TR - Turchia 14
CZ - Repubblica Ceca 13
JP - Giappone 12
AU - Australia 11
BR - Brasile 8
ID - Indonesia 8
MX - Messico 8
RO - Romania 8
PK - Pakistan 7
BD - Bangladesh 6
DK - Danimarca 6
HK - Hong Kong 6
IR - Iran 5
LB - Libano 5
NG - Nigeria 4
PL - Polonia 4
AR - Argentina 3
TW - Taiwan 3
A2 - ???statistics.table.value.countryCode.A2??? 2
DZ - Algeria 2
KZ - Kazakistan 2
LU - Lussemburgo 2
MD - Moldavia 2
NO - Norvegia 2
PH - Filippine 2
UZ - Uzbekistan 2
AE - Emirati Arabi Uniti 1
AM - Armenia 1
BA - Bosnia-Erzegovina 1
EU - Europa 1
GL - Groenlandia 1
HU - Ungheria 1
IQ - Iraq 1
KR - Corea 1
PE - Perù 1
SI - Slovenia 1
SN - Senegal 1
Totale 10.636
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Città #
Southend 773
Fairfield 580
Bologna 457
Chandler 448
Ashburn 430
Woodbridge 310
Ann Arbor 254
Wilmington 251
Seattle 247
Houston 242
Singapore 218
Cambridge 214
Princeton 190
Dublin 153
Jacksonville 133
Dong Ket 126
Lomé 100
New York 99
Padova 91
Redmond 89
Westminster 82
Bern 77
Berlin 72
Milan 68
Nanjing 63
Abidjan 60
Jinan 57
Turin 51
Santa Clara 48
Saint Petersburg 45
Amman 43
Sofia 43
Beijing 38
Changsha 37
San Diego 36
Medford 34
Shenyang 32
Boardman 31
Hebei 29
Mülheim 29
Redwood City 27
Florence 26
Helsinki 26
Amsterdam 25
Brussels 25
Los Angeles 25
Nanchang 24
Valladolid 23
Dearborn 21
Bratislava 18
Parma 17
Tianjin 17
Haikou 16
Des Moines 15
Falls Church 15
Jiaxing 15
Kuban 15
Reggio Emilia 15
Mahé 14
Norwalk 14
Vienna 13
Mountain View 12
Phoenix 12
Taizhou 12
Zhengzhou 12
Fuzhou 11
Modena 11
Ningbo 11
Rome 11
Verona 11
Barcelona 10
Bari 10
Casalecchio di Reno 10
Hyderabad 10
Naples 10
Paris 10
Tokyo 10
Pune 9
Ravenna 9
Vila Franca De Xira 9
York 9
Genoa 8
Grosseto 8
Guangzhou 8
Olalla 8
Olomouc 8
Ancona 7
Bühl 7
Formigine 7
Hangzhou 7
Jakarta 7
Lecce 7
Mumbai 7
Napoli 7
Philadelphia 7
Taiyuan 7
Bremen 6
Costa Mesa 6
Marseille 6
São Paulo 6
Totale 7.129
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Nome #
Inducing cancer indolence by targeting mitochondrial Complex I is potentiated by blocking macrophage-mediated adaptive responses 191
Different mtDNA mutations modify tumor progression in dependence of the degree of respiratory complex I impairment 189
An inherited mitochondrial DNA disruptive mutation shifts to homoplasmy in oncocytic tumor cells. 174
Respiratory complex I is essential to induce a Warburg profile in mitochondria-defective tumor cells 170
A practical approach for the detection of DNA nanostructures in single live human cells by fluorescence microscopy 170
Mutant MYO1F alters the mitochondrial network and induces tumor proliferation in thyroid cancer 170
Inducing respiratory complex I impairment elicits an increase in PGC1α in ovarian cancer 170
Glucocorticoid receptor antagonization propels endogenous cardiomyocyte proliferation and cardiac regeneration 167
NDUFS3 depletion permits complex I maturation and reveals TMEM126A/OPA7 as an assembly factor binding the ND4-module intermediate 165
Alterations in the supramolecular interactions of respiratory chain complexes and enhanced superoxide production by the cytochrome b Y278C mutation which causes a multisystem disorder 164
Peculiar combinations of individually non-pathogenic missense mitochondrial DNA variants cause low penetrance Leber's hereditary optic neuropathy 158
Apoptosis induced by staurosporine in ECV304 cells requires cell shrinkage and upregulation of Cl- conductance 157
The antioxidant function of Bcl-2 preserves cytoskeletal stability of cells with defective respiratory complex I. 156
The Oncojanus Paradigm of Respiratory Complex I 156
Defective oxidative phosphorylation in thyroid oncocytic carcinoma is associated with pathogenic mitochondrial DNA mutations affecting complexes I and III 156
The background of mitochondrial DNA haplogroup J increases the sensitivity of Leber's hereditary optic neuropathy cells to 2,5-hexanedione toxicity. 154
The multifaceted contribution of α-ketoglutarate to tumor progression: An opportunity to exploit? 154
Plasma-activated Ringer's Lactate Solution Displays a Selective Cytotoxic Effect on Ovarian Cancer Cells 149
A Comprehensive Characterization of Mitochondrial DNA Mutations in Glioblastoma Multiforme 147
Complex I impairment in mitochondrial diseases and cancer: parallel roads leading to different outcomes. 142
A cellular model for cancer progression: Role of mitochondrial mutations and metabolism 140
Caspase-independent death of Leber's hereditary optic neuropathy cybrids is driven by energetic failure and mediated by AIF and Endonuclease G. 140
Potential for Mitochondrial DNA Sequencing in the Differential Diagnosis of Gynaecological Malignancies 139
pH difference across the outer mitochondrial membrane measured with a green fluorescent protein mutant 137
Mitochondrial DNA sequencing demonstrates clonality of peritoneal implants of borderline ovarian tumors 136
Cybrid studies establish the causal link between the mtDNA m.3890G>A/MT-ND1 mutation and optic atrophy with bilateral brainstem lesions. 133
Cell death of fibroblasts derived from patients with Leber’s hereditary optic neuropathy mtDNA mutations 131
ATP depletion and caspase independent death of cybrids bearing Leber's Hereditary Optic neuropathy MTDNA mutations incubated in galactose medium. A model for endonuclease G-mediated apoptosis 129
Mild phenotypes and proper supercomplex assembly in human cells carrying the homoplasmic m.15557G > A mutation in cytochrome b gene 127
A Mutation Threshold Distinguishes the Antitumorigenic Effects of the Mitochondrial Gene MTND1, an Oncojanus Function 126
The cytochrome B p.278Y>C mutation causative of a multisystem disorder enhances superoxide production and alters supramolecular interactions of respiratory chain complexes 125
Analysis of Mitochondrial Proteome of Cybrid Cells Harbouring a Truncative Mitochondrial DNA Mutation in Respiratory Complex I 123
The α-ketoglutarate dehydrogenase complex in cancer metabolic plasticity 123
A Nonsense Mitochondrial DNA Mutation Associates with Dysfunction of HIF1α in a Von Hippel-Lindau Renal Oncocytoma 123
Mice harbouring a SCA28 patient mutation in AFG3L2 develop late-onset ataxia associated with enhanced mitochondrial proteotoxicity 123
Deep sequencing unearths Nuclear mitochondrial Sequences under Leber's hereditary optic neuropathy-associated false heteroplasmic mitochondrial DNA variants. 120
Non-Canonical Mechanisms Regulating Hypoxia-Inducible Factor 1 Alpha in Cancer 120
Gamma rays induce a p53-independent mitochondrial biogenesis that is counter-regulated by HIF1α. 119
Disruptive mitochondrial DNA mutations in complex I subunits are markers of oncocytic phenotype in thyroid tumours. 118
Effect of energetic stress and the ceramide analogue C6-ceramide on thyroid oncocytoma cell lines. 117
AIF and endonuclease G are involved in the caspase-indepenent death of cybrids with LHON mutations 116
The genetic and metabolic signature of oncocytic transformation implicates HIF1alpha destabilization 114
Unravelling the Effects of the Mutation m.3571insC/MT-ND1 on Respiratory Complexes Structural Organization 114
The multifaceted effects of metformin on tumor microenvironment 112
Potential Prognostic Role of 18F-FDG PET/CT in Invasive Epithelial Ovarian Cancer Relapse. A Preliminary Study 111
The microbial community dwelling on a biodeteriorated 16th century painting 110
Protection against oxidant-induced apoptosis by exogenous glutathione in Leber Hereditary Optic Neuropathy cybrids. 109
Syndromic parkinsonism and dementia associated with OPA1 missense mutations 109
Evaluation of the energetic efficiency of cells derived from patients with dominant optic neuropathy (DOA). 108
Effect of energetic stress and the ceramide analogue C6-ceramide on thyroid oncocytoma cell lines 108
null 108
Learning from oncocytic tumors: why choose inefficient mitochondria? 105
Respiratory complex I dysfunction due to mitochondrial DNA mutations shifts the voltage threshold for opening of the permeability transition pore toward resting levels 104
Cancer cells contribute to distinct malignant traits depending on their MYC and pJNK relative levels 104
Dansyl acetyl trehalose: a novel tool to investigate the cellular fate of trehalose 104
Mitochondrial metabolism and energy sensing in tumor progression 104
Determination of mitochondrial fusion in fibroblasts from dominant optic atrophy patients bearing the c.2708delttag OPA1 mutation 102
JANEUTICS - From the oncojanus function of mitochondrial genes to anti-cancer therapeutics strategies 102
Targeting respiratory complex I to prevent the Warburg effect. 102
Genome-wide expression profiling and functional characterization of SCA28 lymphoblastoid cell lines reveal impairment in cell growth and activation of apoptotic pathways. 102
Electrochemotherapy in Vulvar Cancer and Cisplatin Combined with Electroporation. Systematic Review and In Vitro Studies 102
Evidence of association of human papillomavirus with prognosis worsening in glioblastoma multiforme 101
A platform independent RNA-Seq protocol for the detection of transcriptome complexity 101
null 99
A Humanized Bone Niche Model Reveals Bone Tissue Preservation Upon Targeting Mitochondrial Complex I in Pseudo-Orthotopic Osteosarcoma 99
Defective ciliogenesis in thyroid hürthle cell tumors is associated with increased autophagy 98
Effect of energetic stress and the ceramide analogue C6-ceramide on thyroid oncocytoma cell lines 96
null 96
Dominant optic neuropathy: analysis of the energetic efficiency and mitochondrial dynamics 91
OPA 1 mutations associated with dominant optic atrophy impair oxidative phosphorylation and mitochondrial fusion. 91
Mitochondrial DNA mutations in relation to cancer: the model of thyroid oncocytoma 89
Relevance of Mitochondrial Genetics and Metabolism in Cancer Development 89
Pathogenic Mitochondrial DNA Mutation Load Inversely Correlates with Malignant Features in Familial Oncocytic Parathyroid Tumors Associated with Hyperparathyroidism-Jaw Tumor Syndrome 88
Dysregulation of Parkin-mediated mitophagy in thyroid Hürthle cell tumors 85
NDUFS3 knockout cancer cells and molecular docking reveal specificity and mode of action of anti-cancer respiratory complex I inhibitors 80
The energetic failure caused by severe mutations in the mitochondrial genome is not rescued by Bcl-2 overexpression 80
Novel mutations in mitochondrial respiratory complexes and their functional relevance in thyroid oncocytoma. 76
OPA1 directly interacts with respiratory complexes and AIF. 76
High-resolution genomic profiling of thyroid lesions uncovers preferential copy number gains affecting mitochondrial biogenesis loci in the oncocytic variants 76
MicroRNA and Metabolic Profiling of a Primary Ovarian Neuroendocrine Carcinoma Pulmonary-Type Reveals a High Degree of Similarity with Small Cell Lung Cancer 75
Energetic efficiency and mitochondrial dynamics in fibroblasts derived from patients with optic neuropathies. 74
Oxidative phosphorylation dysfunction in fibroblasts bearing different pathological OPA1 mutations. 72
DNA Nanostructures assembly and potential use as intracellular biosensors in single live human cells 72
Effect of bcl-2 on the oxidative phosphorylation efficiency of cells with defective respiratory complex I. 72
The neglected liaison: Targeting cancer cell metabolic reprogramming modifies the composition of non‐malignant populations of the tumor microenvironment 72
Microstructured soft devices for the growth and analysis of populations of homogenous multicellular tumor spheroids 72
MCJ/DNAJC15 mitochondrial chaperone as a metabolic “balance needle” in ovarian cancer chemoresistance 67
DNA Nanostructures as Intracellular Biosensors in Single Live Human Cells 66
The Human Mitochondrial Genome: From Basic Biology to Disease 64
Respiratory Chain Function and Mitochondrial Dynamics in Leber's Hereditary Optic Neuropathy (LHON) and OPA1-Related Dominant Optic Atrophy (DOA) Fibroblasts. 63
Towards triplex-based intracellular pH biosensors based on self-assembled DNA nanostructures 60
Respiratory Complex I dysfunction in cancer: from a maze of cellular adaptive responses to potential therapeutic strategies 60
Role of mitochondria in the regulation of apoptosis and autophagy: molecular mechanisms and effects of pathogenic mutations”. 57
mtDNA mutations in cancer 56
Genetic variants affecting NQO1 protein levels impact the efficacy of idebenone treatment in Leber hereditary optic neuropathy 55
AI is a viable alternative to high throughput screening: a 318-target study 53
Respiratory complex I null cancer cells and molecular docking reveal specificity and mode of action inhibitors with anticancer activity 38
Platinum-induced mitochondrial DNA mutations confer lower sensitivity to paclitaxel by impairing tubulin cytoskeletal organization 34
Downregulation of PLIN2 in human dermal fibroblasts impairs mitochondrial function in an age-dependent fashion and induces cell senescence via GDF15 29
Molecular and metabolic features of oncocytomas: seeking the blueprints of indolent cancers 28
Totale 10.908
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Categoria #
all - tutte 27.227
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 27.227
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20202.244 0 0 50 156 271 244 282 355 417 185 116 168
2020/20211.557 289 117 33 59 25 136 32 86 144 102 109 425
2021/20221.999 143 72 115 119 166 106 73 151 70 192 472 320
2022/20232.261 202 307 110 284 133 167 80 119 391 76 211 181
2023/20241.016 50 103 53 96 70 201 45 55 39 158 78 68
2024/2025571 148 337 86 0 0 0 0 0 0 0 0 0
Totale 11.007