CRIS Current Research Information System

GENTILUCCI, LUCA
 Distribuzione geografica
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Continente #
NA - Nord America 6.738
EU - Europa 5.923
AS - Asia 2.724
AF - Africa 470
SA - Sud America 13
OC - Oceania 10
Continente sconosciuto - Info sul continente non disponibili 6
Totale 15.884
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Nazione #
US - Stati Uniti d'America 6.718
IT - Italia 1.937
GB - Regno Unito 1.431
CN - Cina 1.103
SG - Singapore 717
DE - Germania 661
VN - Vietnam 434
SE - Svezia 381
UA - Ucraina 368
IN - India 257
FR - Francia 247
IE - Irlanda 229
RU - Federazione Russa 211
TG - Togo 205
ZA - Sudafrica 110
CI - Costa d'Avorio 100
BG - Bulgaria 91
EE - Estonia 87
JO - Giordania 67
FI - Finlandia 56
CH - Svizzera 53
BE - Belgio 34
NL - Olanda 33
HK - Hong Kong 31
SC - Seychelles 26
NG - Nigeria 25
HR - Croazia 24
ES - Italia 20
JP - Giappone 20
ID - Indonesia 19
CA - Canada 18
IR - Iran 16
LB - Libano 16
RO - Romania 15
AT - Austria 10
AU - Australia 9
CL - Cile 9
PK - Pakistan 9
TR - Turchia 9
GR - Grecia 8
PL - Polonia 7
EU - Europa 6
CZ - Repubblica Ceca 5
PT - Portogallo 5
IL - Israele 4
IQ - Iraq 4
BD - Bangladesh 3
BR - Brasile 3
NO - Norvegia 3
SI - Slovenia 3
TH - Thailandia 3
TN - Tunisia 3
TW - Taiwan 3
MX - Messico 2
AE - Emirati Arabi Uniti 1
AM - Armenia 1
HU - Ungheria 1
KZ - Kazakistan 1
LA - Repubblica Popolare Democratica del Laos 1
LI - Liechtenstein 1
LK - Sri Lanka 1
MK - Macedonia 1
MW - Malawi 1
NZ - Nuova Zelanda 1
OM - Oman 1
PE - Perù 1
PH - Filippine 1
SA - Arabia Saudita 1
SK - Slovacchia (Repubblica Slovacca) 1
UZ - Uzbekistan 1
Totale 15.884
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Città #
Southend 1.248
Fairfield 768
Singapore 611
Chandler 604
Ashburn 530
Santa Clara 516
Bologna 376
Woodbridge 375
Wilmington 339
Seattle 336
Princeton 300
Cambridge 285
Houston 283
Ann Arbor 265
Dong Ket 264
Jacksonville 262
Dublin 220
Lomé 205
Boardman 182
Nanjing 152
Padova 131
Westminster 131
Milan 119
Abidjan 100
Berlin 98
Sofia 91
Jinan 83
Beijing 80
Amman 67
Shenyang 67
Saint Petersburg 64
Bremen 61
Helsinki 51
Hebei 50
Medford 49
Mülheim 46
San Diego 45
Changsha 42
Turin 42
Guangzhou 40
Redmond 40
Rome 40
Shanghai 39
Nanchang 37
New York 35
Tianjin 34
Brussels 32
Haikou 31
Zhengzhou 31
Hangzhou 30
Des Moines 27
Mountain View 27
Mahé 25
Abeokuta 24
Cesena 24
Redwood City 24
Forlì 23
Los Angeles 23
Wuhan 23
Bari 19
Florence 19
Jiaxing 19
Norwalk 19
Modena 18
Verona 18
Falls Church 17
Jakarta 17
Boydton 16
Forlimpopoli 16
Pessac 16
San Mauro Pascoli 16
Tokyo 16
Zurich 16
Ningbo 15
San Venanzo 15
Taizhou 15
Chicago 14
Kunming 14
Dearborn 13
Phoenix 13
Shenzhen 13
Taiyuan 13
Bern 12
Davis 12
Fremont 12
Imperia 12
Paris 12
Parma 12
Naples 11
Hong Kong 10
Lanzhou 10
London 10
Olalla 10
Pune 10
Bühl 9
Chengdu 9
Falkenstein 9
Moscow 9
Ravenna 9
Venezia 9
Totale 10.701
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Nome #
Inibitori dei processi infiammatori cronici connessi allo sviluppo di tumori (Inhibitors of the chronic inflammatory processes connected to tumor development) 616
Targeting integrins αvβ3 and α5β1 with new β-lactam derivatives 187
Dehydro-beta-proline Containing Alpha-4-beta-1 Integrin Antagonists: Stereochemical Recognition in Ligand-Receptor Interplay 186
Leukocyte Integrin Antagonists as a Novel Option to Treat Dry Age-Related Macular Degeneration 183
A novel family of minimal PMRI cyclic peptides as versatile scaffolds for generating new molecular topology. 182
Thixotropic peptide-based physical hydrogels applied to three-dimensional cell culture 173
A simple route towards peptide analogues containing substituted (S)- or (R)-tryptophans 172
A novel family of minimalist opioid peptides deprived of the classic pharmacophores 168
Modern tools for the chemical ligation and synthesis of modified peptides and proteins 168
A convenient synthesis of functionalized isoxazolines and related 5-hydroxy-isoxazolidine-4-carboxylates 167
Constraining Endomorphin-1 by β,α-Hybrid Dipeptide/Heterocycle Scaffolds: Identification of a Novel κ-Opioid Receptor Selective Partial Agonist 167
5-aminomethyloxazolidine-2,4-dione hybrid α/β-dipeptide scaffolds as inductors of constrained conformations: Applications to the synthesis of integrin antagonists 164
Chemical Modifications Designed to Improve Peptide Stability: Incorporation of Non-Natural Amino Acids, Pseudo-Peptide Bonds, and Cyclization 154
A microwave-enhanced, Lewis acid-catalyzed synthesis of 1,3-dioxolanes and oxazolines from epoxides 153
Ac-D-Trp-PheNH2 AND Ac-D-Trp-Phe-GlyNH2 - A NEW CLASS OF UNUSUAL OPIOID PEPTIDES 147
DS-70, a novel and potent α4 integrin antagonist, is an effective treatment for experimental allergic conjunctivitis in guinea pigs 144
Practical synthesis of 3-bromo-5,6-dihydropyridin-2-ones via β,γ-unsaturated α-bromo-ketene/imine cycloaddition 142
Antiangiogenic Effect of Dual/Selective α5β1/αvβ3 Integrin Antagonists Designed on Partially Modified Retro-Inverso Cyclotetrapeptide Mimetics 142
A straightforward route to enantiopure 2-substituted-3,4-dehydro-beta-proline via ring closing metathesis 139
Highly Regio- and Diastereoselective Palladium-Catalyzed Allylic Substitution. Synthesis of 3-(2-aminobutylidene)-4-arylazetidin-2-ones 137
An improved microwave assisted protocol for Yonemitsu-type trimolecular condensation 137
An investigation of the reactivity of MCPBA and alpha-bromoalkenes under traditional or microwave-assisted conditions: Selective formation of epoxides or allylic bromides. 135
alpha-Bromo-beta,gamma-unsaturated Ketenes as Valuable Intermediates in the Synthesis of alpha-Amino-beta,gamma-Unsaturated Acids 134
Could Dissecting the Molecular Framework of β-Lactam Integrin Ligands Enhance Selectivity? 134
Controlling Cyclopeptide Backbone Conformation with β/α-Hybrid Peptide–Heterocycle Scaffolds 134
Functional Selectivity and Antinociceptive Effects of a Novel KOPr Agonist 134
Asymmetric Synthesis of three and four membered ring heterocycles 133
Convenient Synthesis of the Antibiotic Linezolid via an Oxazolidine-2,4-dione Intermediate Derived from the Chiral Building Block Isoserine 132
Diagnostic implementation of fast and selective integrin-mediated adhesion of cancer cells on functionalized zeolite L monolayers 131
DESIGN AND SYNTHESIS OF OPIOID PEPTIDE ANALOGUES AND MIMETICS 131
Integrin Ligands with α/β-Hybrid Peptide Structure: Design, Bioactivity, and Conformational Aspects 131
Zinc Metal-Promoted Nucleophilic Addition of Azetidin-2-ones to Aldehydes and Nitriles 128
Exploring the reactivity of alkylidene malonamides: synthesis of polyfunctionalized isoxazolidinones, aziridines and oxazolines 128
Green synthesis of bioactive oligopeptides promoted by recyclable nanocrystalline hydroxyapatite 128
New trends in the development of opioid peptide analogues as advanced remedies for pain relief 126
Pharmacological Characterization of µ-Opioid Receptor Agonists with Biased G Protein or β-Arrestin Signaling, and Computational Study of Conformational Changes during Receptor Activation 126
Synthesis of mixed MOR/KOR efficacy cyclic opioid peptide analogs with antinociceptive activity after systemic administration 124
Integrin-targeting dye-doped peg-shell/silica-core nanoparticles mimicking the proapoptotic Smac/DIABLO protein 124
Opioid Activity Profiles of Oversimplified Peptides Lacking in the Protonable N-Terminus 123
Dehydro-beta-amino Acid Containing Peptides as Promising Sequences for Drug Development 122
Design of α/β-hybrid peptide ligands of α4β1 integrin equipped with a linkable side chain for chemoselective biofunctionalization of microstructured materials 122
Synthesis and Biological Evaluation of Azido- and Aziridino-hydroxyl-beta -lactams through Stereo- and Regioselective Epoxide Ring Opening. 121
The Inverse Type II β-Turn on D-Trp-Phe, a Pharmacophoric Motif for MOR Agonists. 120
A new generation of opioid peptidomimetics acting as central and/or peripheral analgesics 120
Enzymatic Resolution of Ethyl 3-Hydroxy-2(1'substituted-methylidene)-butyrate by Pseudomonas Cepacia Lipase Catalyzed Acetylation 120
Synthesis and evaluation of the affinity toward mu-opioid receptor of atypical, lipophilic ligands based on the sequence c[Tyr-Pro-Trp-Phe-Gly-]. 119
Inhibition of cancer cell adhesion by heterochiral Pro-containing RGD mimetics. 119
Modulation of αvβ3- and α5β1-integrin-mediated adhesion by dehydro-β-amino acids containing peptidomimetics 117
Highly regio- and stereoselective palladium-catalyzed allylic carbonate amination. A practical route to dehydro-beta-amino esters 116
Topological exploration of cyclic endomorphin-1 analogues, structurally defined models for investigating the bioactive conformation of MOR agonists. 115
Asymmetric Synthesis of Three and Four Membered Ring Heterocycles - Chapter 1 115
Cyclotetrapeptide Mimics based on a 13-Membered, Partially Modified Retro-Inverso Structure 115
Molecular Docking of Opiates and Opioid Peptides, a Tool for the Design of Selective Agonists and Antagonists, and for the Investigation of Atypical Ligand-Receptor Interactions 115
Synthesis and assay of retro-α4β1 integrin-targeting motifs 114
Synthesis and Biological Evaluation of Nonpeptide alpha-v-beta-3/alpha-5-beta-1 Integrin Dual Antagonists containing 5,6-Dihydropyridin-2-one Scaffolds 113
Synthesis of dehydro-beta-amino esters via highly regioselective amination of allylic carbonates 113
Heterocyclic Scaffolds in the Design of Peptidomimetic Integrin Ligands: Synthetic Strategies, Structural Aspects, and Biological Activity 113
In-peptide synthesis of di-oxazolidinone and dehydroamino acid-oxazolidinone motifs as β-turn inducers 113
Lewis acid induced highly regioselective synthesis of a new class of substituted isoxazolidines 113
Highly Diastereoselective Allylic Azide Formation and Isomerization. Synthesis of 3(2'-Amino)-beta-lactams 111
Development of isoxazoline-containing peptidomimetics as dual alpha-v-beta-3 and alpha-5-beta-1 integrin ligands. 111
Controlled solid phase peptide bond formation using N-carboxyanhydrides and PEG resins in water. 111
Unusual Amino Acids: Synthesis and Introduction into Naturally Occurring Peptides and Biologically Active Analogues 110
Investigation of the Interaction Between the Atypical Agonist c[YpwFG] and MOR 110
Cyclopeptide analogs for generating new molecular and 3D diversity 109
null 105
Synthesis of chiral non-racemic intermediates and Arg-Gly-Asp mimetics by CaLB-catalyzed resolution 104
Peptide bond formation using unprotected N-carboxyanhydrides under green chemistry conditions 104
Peptides and peptidomimetics in medicine, surgery, and biotecnology 103
Dehydro-beta-amino acids as scaffolds for the preparation of alpha-v-beta-3, alpha-5-beta-1 and alpha-4-beta-1 integrin ligands 103
NEW PEPTIDOMIMETIC α4β1-INTEGRIN ANTAGONISTS FOR REDUCING INFLAMMATION AND ALLERGIC REACTIONS 103
Synthesis of Ethyl 5-Hydroxyisoxazolidine-4-carboxylates via Michael Addition/Intramolecular Hemiketalisation 103
Cyclic side-chain-linked opioid analogs utilizing cis- and trans-4-aminocyclohexyl-d-alanine 103
Design and characterization of opioid ligands based on cycle-in-macrocycle scaffold 103
Design of κ-Opioid Receptor Agonists for the Development of Potential Treatments of Pain with Reduced Side Effects 101
Stereoselective synthesis of a new class of spiro-beta-lactams via epoxide ring opening 101
Atypical mu-opioid agonists: reconsideration of the requisites for receptor activation 99
Versatile Picklocks to Access All Opioid Receptors: Tuning the Selectivity and Functional Profile of the Cyclotetrapeptide c[Phe- d -Pro-Phe-Trp] (CJ-15,208) 99
Cyclic endomorphin analogs in targeting opioid receptors to achieve pain relief 99
Stereoselective synthesis of a new class of spiro-beta-lactams via epoxide ring opening 98
Synthesis and biological evaluation of unprecedented classes of spiro-beta-lactams and azido-beta-lactams as acyl-CoA:cholesterol acyltransferase inhibitors 98
DETERMINATION OF THE BIOLOGICALLY ACTIVE STRUCTURE OF THE ATYPICAL MOR-LIGAND c[D-Asp-1-amide-beta-Ala-D-Trp-Phe] AND ANALOGUES BY NMR AND MOLECULAR DOCKING 98
Short peptidomimetics containing heterocyclic scaffolds as alpha-v-beta-3 integrins ligands. 98
Functionalizations of the C3 side chain of densely substituted azetidin-2-ones 97
Current Medicinal Chemistry 95
One-Pot Synthesis of Poly-Substituted Tetramic Acids for the Preparation of Reverse-Turn Mimics 95
Ring size in cyclic endomorphin-2 analogs modulates receptor binding affinity and selectivity 95
Preparation of Non-Toxic Fluorescent Peptide-Coated Silica/PEG Nanoparticles from Peptide-Block Copolymer Conjugates 94
Synthesis of Enantiomerically Pure alpha-v-beta-3 Integrin ligands Based on a 5,6-Dihydropyridin-2-one Scaffold. 94
null 93
Synthesis and Analysis of the Conformational Preferences of 5- Aminomethyloxazolidine-2,4-dione Scaffolds: First Examples of beta2- and beta2,2-Homo-Freidinger Lactam Analogues 93
Biologically active analogues of naturally occurring peptides 93
Design and synthesis of Alpha-v-beta-3 and Alpha-5-beta-1 integrin ligands as delivery systems for fluorescent molecules 93
Easy preparation of dehydroalanine building blocks equipped with oxazolidin-2-one chiral auxiliaries, and applications to the stereoselective synthesis of substituted tryptophans 93
Synthesis and Conformational Analysis of Cyclotetrapeptide Mimetic beta-Turn Templates and Validation as 3D Scaffolds 93
Interactions between atypical opioid agonists and MOR 93
Stereoselective Synthesis of Linear and Cyclic Dehydro-beta-amino Acids for the Preparation of alpha-v-beta-3 and alpha-5-beta-1 Integrin Inhibitors 92
Alkylidene malonamides and acetacetamides as intermediates for the preparation of constrained dipeptide mimetics. 91
Synthesis of Constrained Peptidomimetics Containing 2-Oxo-1,3-oxazolidine-4-carboxylic Acids 91
Re-discussion of the importance of ionic interactions in stabilizing ligand-opioid receptor complex and in activating signal transduction 91
Totale 12.569
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Categoria #
all - tutte 42.880
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 42.880
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20202.062 0 0 0 0 0 272 384 436 400 258 93 219
2020/20212.201 420 122 101 153 41 113 146 170 229 125 134 447
2021/20222.705 343 155 186 132 262 146 95 294 107 148 409 428
2022/20233.089 264 447 156 382 224 261 119 161 592 91 236 156
2023/20241.376 91 135 80 119 169 284 101 98 43 99 83 74
2024/20252.394 192 599 379 241 767 216 0 0 0 0 0 0
Totale 16.277