CRIS Current Research Information System

GENTILUCCI, LUCA
 Distribuzione geografica
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Continente #
NA - Nord America 9.058
AS - Asia 8.335
EU - Europa 7.396
AF - Africa 673
SA - Sud America 385
OC - Oceania 20
Continente sconosciuto - Info sul continente non disponibili 6
Totale 25.873
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Nazione #
US - Stati Uniti d'America 8.926
CN - Cina 2.456
IT - Italia 2.444
SG - Singapore 2.144
VN - Vietnam 2.004
GB - Regno Unito 1.474
DE - Germania 805
HK - Hong Kong 575
FR - Francia 479
SE - Svezia 387
UA - Ucraina 379
RU - Federazione Russa 342
IN - India 341
IE - Irlanda 266
BR - Brasile 257
NL - Olanda 213
TG - Togo 205
CI - Costa d'Avorio 188
JP - Giappone 158
KR - Corea 148
FI - Finlandia 143
ZA - Sudafrica 122
BG - Bulgaria 91
SC - Seychelles 91
EE - Estonia 89
BD - Bangladesh 87
CA - Canada 79
JO - Giordania 68
CH - Svizzera 58
PH - Filippine 57
AR - Argentina 45
ID - Indonesia 45
TH - Thailandia 41
BE - Belgio 39
ES - Italia 39
MX - Messico 33
TW - Taiwan 30
EC - Ecuador 29
HR - Croazia 28
IQ - Iraq 27
PK - Pakistan 27
NG - Nigeria 26
TR - Turchia 23
AT - Austria 20
PL - Polonia 20
IR - Iran 19
AU - Australia 17
CL - Cile 17
CO - Colombia 17
LB - Libano 17
RO - Romania 16
UZ - Uzbekistan 12
PT - Portogallo 11
GR - Grecia 10
SA - Arabia Saudita 9
LT - Lituania 8
CZ - Repubblica Ceca 7
MA - Marocco 7
AE - Emirati Arabi Uniti 6
EU - Europa 6
IL - Israele 6
KZ - Kazakistan 6
PE - Perù 6
TN - Tunisia 6
VE - Venezuela 6
CR - Costa Rica 5
ET - Etiopia 5
PY - Paraguay 5
RS - Serbia 5
AZ - Azerbaigian 4
DZ - Algeria 4
EG - Egitto 4
HU - Ungheria 4
JM - Giamaica 4
NP - Nepal 4
SI - Slovenia 4
AO - Angola 3
BH - Bahrain 3
KE - Kenya 3
MY - Malesia 3
NO - Norvegia 3
AL - Albania 2
BB - Barbados 2
BN - Brunei Darussalam 2
BZ - Belize 2
CY - Cipro 2
DK - Danimarca 2
DO - Repubblica Dominicana 2
KG - Kirghizistan 2
LV - Lettonia 2
ML - Mali 2
NZ - Nuova Zelanda 2
OM - Oman 2
SN - Senegal 2
UY - Uruguay 2
AM - Armenia 1
BA - Bosnia-Erzegovina 1
BO - Bolivia 1
BY - Bielorussia 1
DM - Dominica 1
Totale 25.853
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Città #
Singapore 1.448
Southend 1.248
Ashburn 873
Fairfield 768
Chandler 604
San Jose 601
Santa Clara 542
Bologna 528
Hong Kong 513
Ho Chi Minh City 441
Hanoi 391
Woodbridge 375
Seattle 347
Wilmington 341
Hefei 335
Beijing 314
Princeton 302
Houston 290
Cambridge 285
Jacksonville 266
Ann Arbor 265
Dong Ket 264
Dublin 247
Lomé 205
Boardman 193
Abidjan 188
Milan 165
Lauterbourg 155
Nanjing 154
Los Angeles 139
Council Bluffs 138
Tokyo 134
Padova 131
Westminster 131
Seoul 121
Helsinki 116
Dallas 110
Berlin 104
Sofia 91
Jinan 85
New York 85
Shanghai 77
Guangzhou 73
Rome 73
Buffalo 72
Da Nang 71
Shenyang 70
Amman 68
Haiphong 65
Saint Petersburg 64
Bremen 61
Tianjin 59
Frankfurt am Main 58
Changsha 54
Turin 52
Hebei 50
Medford 49
Redondo Beach 47
Mülheim 46
San Diego 45
Zhengzhou 44
Hangzhou 40
Redmond 40
Chicago 39
Nanchang 39
Forlì 38
Brussels 36
Munich 36
São Paulo 35
Haikou 31
Wuhan 31
Des Moines 29
Bari 28
Atlanta 27
Bengaluru 27
Jakarta 27
Mountain View 27
Phoenix 26
Biên Hòa 25
Falkenstein 25
Mahé 25
Shenzhen 25
Yubileyny 25
Abeokuta 24
Cesena 24
Orem 24
Redwood City 24
Modena 23
Toronto 23
Verona 22
Florence 21
Jiaxing 21
The Dalles 21
London 20
Norwalk 19
Genoa 18
Kunming 18
Ningbo 18
Washington 18
Zurich 18
Totale 16.268
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Nome #
Inibitori dei processi infiammatori cronici connessi allo sviluppo di tumori (Inhibitors of the chronic inflammatory processes connected to tumor development) 816
Targeting integrins αvβ3 and α5β1 with new β-lactam derivatives 295
Modern tools for the chemical ligation and synthesis of modified peptides and proteins 292
Synthesis and Biological Evaluation of Nonpeptide alpha-v-beta-3/alpha-5-beta-1 Integrin Dual Antagonists containing 5,6-Dihydropyridin-2-one Scaffolds 278
Leukocyte Integrin Antagonists as a Novel Option to Treat Dry Age-Related Macular Degeneration 276
Dehydro-beta-proline Containing Alpha-4-beta-1 Integrin Antagonists: Stereochemical Recognition in Ligand-Receptor Interplay 270
Constraining Endomorphin-1 by β,α-Hybrid Dipeptide/Heterocycle Scaffolds: Identification of a Novel κ-Opioid Receptor Selective Partial Agonist 270
Design of κ-Opioid Receptor Agonists for the Development of Potential Treatments of Pain with Reduced Side Effects 256
Thixotropic peptide-based physical hydrogels applied to three-dimensional cell culture 253
Could Dissecting the Molecular Framework of β-Lactam Integrin Ligands Enhance Selectivity? 248
Conjecturing about Small-Molecule Agonists and Antagonists of α4β1 Integrin: From Mechanistic Insight to Potential Therapeutic Applications 244
Preparation of Non-Toxic Fluorescent Peptide-Coated Silica/PEG Nanoparticles from Peptide-Block Copolymer Conjugates 238
A novel family of minimal PMRI cyclic peptides as versatile scaffolds for generating new molecular topology. 238
5-aminomethyloxazolidine-2,4-dione hybrid α/β-dipeptide scaffolds as inductors of constrained conformations: Applications to the synthesis of integrin antagonists 237
Chemical Modifications Designed to Improve Peptide Stability: Incorporation of Non-Natural Amino Acids, Pseudo-Peptide Bonds, and Cyclization 235
A convenient synthesis of functionalized isoxazolines and related 5-hydroxy-isoxazolidine-4-carboxylates 229
A simple route towards peptide analogues containing substituted (S)- or (R)-tryptophans 220
DS-70, a novel and potent α4 integrin antagonist, is an effective treatment for experimental allergic conjunctivitis in guinea pigs 219
Integrin-targeting dye-doped peg-shell/silica-core nanoparticles mimicking the proapoptotic Smac/DIABLO protein 216
Synthesis and Antiproliferative Activity against Cancer Cells of Indole-Aryl-Amide Derivatives 214
A microwave-enhanced, Lewis acid-catalyzed synthesis of 1,3-dioxolanes and oxazolines from epoxides 213
Practical synthesis of 3-bromo-5,6-dihydropyridin-2-ones via β,γ-unsaturated α-bromo-ketene/imine cycloaddition 211
Diagnostic implementation of fast and selective integrin-mediated adhesion of cancer cells on functionalized zeolite L monolayers 211
alpha-Bromo-beta,gamma-unsaturated Ketenes as Valuable Intermediates in the Synthesis of alpha-Amino-beta,gamma-Unsaturated Acids 210
Highly Regio- and Diastereoselective Palladium-Catalyzed Allylic Substitution. Synthesis of 3-(2-aminobutylidene)-4-arylazetidin-2-ones 207
A novel family of minimalist opioid peptides deprived of the classic pharmacophores 206
Functional Selectivity and Antinociceptive Effects of a Novel KOPr Agonist 206
Antiangiogenic Effect of Dual/Selective α5β1/αvβ3 Integrin Antagonists Designed on Partially Modified Retro-Inverso Cyclotetrapeptide Mimetics 205
Green synthesis of bioactive oligopeptides promoted by recyclable nanocrystalline hydroxyapatite 203
Integrin Ligands with α/β-Hybrid Peptide Structure: Design, Bioactivity, and Conformational Aspects 203
Synthesis of mixed MOR/KOR efficacy cyclic opioid peptide analogs with antinociceptive activity after systemic administration 202
Ac-D-Trp-PheNH2 AND Ac-D-Trp-Phe-GlyNH2 - A NEW CLASS OF UNUSUAL OPIOID PEPTIDES 201
Peptide bond formation using unprotected N-carboxyanhydrides under green chemistry conditions 201
Pharmacological Characterization of µ-Opioid Receptor Agonists with Biased G Protein or β-Arrestin Signaling, and Computational Study of Conformational Changes during Receptor Activation 199
Design of α/β-hybrid peptide ligands of α4β1 integrin equipped with a linkable side chain for chemoselective biofunctionalization of microstructured materials 197
Zinc Metal-Promoted Nucleophilic Addition of Azetidin-2-ones to Aldehydes and Nitriles 195
Controlling Cyclopeptide Backbone Conformation with β/α-Hybrid Peptide–Heterocycle Scaffolds 195
Exploring the reactivity of alkylidene malonamides: synthesis of polyfunctionalized isoxazolidinones, aziridines and oxazolines 192
Asymmetric Synthesis of three and four membered ring heterocycles 191
A straightforward route to enantiopure 2-substituted-3,4-dehydro-beta-proline via ring closing metathesis 190
PacDOCK: A Web Server for Positional Distance-Based and Interaction-Based Analysis of Docking Results 190
An improved microwave assisted protocol for Yonemitsu-type trimolecular condensation 189
New trends in the development of opioid peptide analogues as advanced remedies for pain relief 187
Synthesis and Biological Evaluation of Azido- and Aziridino-hydroxyl-beta -lactams through Stereo- and Regioselective Epoxide Ring Opening. 187
An investigation of the reactivity of MCPBA and alpha-bromoalkenes under traditional or microwave-assisted conditions: Selective formation of epoxides or allylic bromides. 187
Synthesis and evaluation of the affinity toward mu-opioid receptor of atypical, lipophilic ligands based on the sequence c[Tyr-Pro-Trp-Phe-Gly-]. 186
Convenient Synthesis of the Antibiotic Linezolid via an Oxazolidine-2,4-dione Intermediate Derived from the Chiral Building Block Isoserine 186
Synthesis and assay of retro-α4β1 integrin-targeting motifs 185
Investigation of the Interaction Between the Atypical Agonist c[YpwFG] and MOR 184
Peptides inhibiting the assembly of monomeric human l‐lactate dehydrogenase into catalytically active homotetramer decrease the synthesis of lactate in cultured cells 183
Topological exploration of cyclic endomorphin-1 analogues, structurally defined models for investigating the bioactive conformation of MOR agonists. 183
Identification of c[D-Trp-Phe-β-Ala-β-Ala], the First κ-Opioid Receptor-Specific Negative Allosteric Modulator 181
DESIGN AND SYNTHESIS OF OPIOID PEPTIDE ANALOGUES AND MIMETICS 181
Modulation of αvβ3- and α5β1-integrin-mediated adhesion by dehydro-β-amino acids containing peptidomimetics 181
Asymmetric Synthesis of Three and Four Membered Ring Heterocycles - Chapter 1 180
The Inverse Type II β-Turn on D-Trp-Phe, a Pharmacophoric Motif for MOR Agonists. 179
Dehydro-beta-amino Acid Containing Peptides as Promising Sequences for Drug Development 178
Opioid Activity Profiles of Oversimplified Peptides Lacking in the Protonable N-Terminus 177
In-peptide synthesis of di-oxazolidinone and dehydroamino acid-oxazolidinone motifs as β-turn inducers 176
Design, Pharmacological Characterization, and Molecular Docking of Minimalist Peptidomimetic Antagonists of α4β1 Integrin 174
Highly Diastereoselective Allylic Azide Formation and Isomerization. Synthesis of 3(2'-Amino)-beta-lactams 171
Controlled solid phase peptide bond formation using N-carboxyanhydrides and PEG resins in water. 171
Expedient recycling of peptide organocatalysts using a nanocrystalline hydroxyapatite catching system 168
Unusual Amino Acids: Synthesis and Introduction into Naturally Occurring Peptides and Biologically Active Analogues 168
Highly regio- and stereoselective palladium-catalyzed allylic carbonate amination. A practical route to dehydro-beta-amino esters 168
Cyclotetrapeptide Mimics based on a 13-Membered, Partially Modified Retro-Inverso Structure 167
Introduction of hydroxyl- or keto- functionalities into the side chain of azetidin-2-ones via allylic bromide rearrangement, followed by supported reagent substitution 166
NEW PEPTIDOMIMETIC α4β1-INTEGRIN ANTAGONISTS FOR REDUCING INFLAMMATION AND ALLERGIC REACTIONS 166
Peptide direct growth on poly(acrylic acid)/poly(vinyl alcohol) electrospun fibers coated with branched poly(ethylenimine): A solid-phase approach for scaffolds biofunctionalization 165
Design and Pharmacological Characterization of α4β1 Integrin Cyclopeptide Agonists: Computational Investigation of Ligand Determinants for Agonism versus Antagonism 165
Peptides and peptidomimetics in medicine, surgery, and biotecnology 165
Purification from Deinococcus radiodurans of a 66 kDa ABC transporter acting on peptides containing at least 3 amino acids 165
Functionalizations of the C3 side chain of densely substituted azetidin-2-ones 163
A new generation of opioid peptidomimetics acting as central and/or peripheral analgesics 163
Synthesis of dehydro-beta-amino esters via highly regioselective amination of allylic carbonates 162
Heterocyclic Scaffolds in the Design of Peptidomimetic Integrin Ligands: Synthetic Strategies, Structural Aspects, and Biological Activity 162
Lewis acid induced highly regioselective synthesis of a new class of substituted isoxazolidines 162
Enzymatic Resolution of Ethyl 3-Hydroxy-2(1'substituted-methylidene)-butyrate by Pseudomonas Cepacia Lipase Catalyzed Acetylation 162
One-Pot Synthesis of Poly-Substituted Tetramic Acids for the Preparation of Reverse-Turn Mimics 161
Inhibition of cancer cell adhesion by heterochiral Pro-containing RGD mimetics. 161
Cyclopeptide analogs for generating new molecular and 3D diversity 161
Selective detection of α4β1 integrin (VLA-4)-expressing cells using peptide-functionalized nanostructured materials mimicking endothelial surfaces adjacent to inflammatory sites 161
Stereoselective synthesis of a new class of spiro-beta-lactams via epoxide ring opening 159
Versatile Picklocks to Access All Opioid Receptors: Tuning the Selectivity and Functional Profile of the Cyclotetrapeptide c[Phe- d -Pro-Phe-Trp] (CJ-15,208) 158
Synthesis and Conformational Analysis of Cyclotetrapeptide Mimetic beta-Turn Templates and Validation as 3D Scaffolds 158
Development of isoxazoline-containing peptidomimetics as dual alpha-v-beta-3 and alpha-5-beta-1 integrin ligands. 156
Cyclic side-chain-linked opioid analogs utilizing cis- and trans-4-aminocyclohexyl-d-alanine 156
Molecular Docking of Opiates and Opioid Peptides, a Tool for the Design of Selective Agonists and Antagonists, and for the Investigation of Atypical Ligand-Receptor Interactions 155
Stereoselective synthesis of a new class of spiro-beta-lactams via epoxide ring opening 154
Synthesis of chiral non-racemic intermediates and Arg-Gly-Asp mimetics by CaLB-catalyzed resolution 154
Design and characterization of opioid ligands based on cycle-in-macrocycle scaffold 153
Synthesis of Ethyl 5-Hydroxyisoxazolidine-4-carboxylates via Michael Addition/Intramolecular Hemiketalisation 152
DETERMINATION OF THE BIOLOGICALLY ACTIVE STRUCTURE OF THE ATYPICAL MOR-LIGAND c[D-Asp-1-amide-beta-Ala-D-Trp-Phe] AND ANALOGUES BY NMR AND MOLECULAR DOCKING 151
Design and synthesis of Alpha-v-beta-3 and Alpha-5-beta-1 integrin ligands as delivery systems for fluorescent molecules 151
Synthesis of Enantiomerically Pure alpha-v-beta-3 Integrin ligands Based on a 5,6-Dihydropyridin-2-one Scaffold. 150
Integrin-targeting peptides for the design of functional cell-responsive biomaterials 150
Stereoselective Synthesis of Linear and Cyclic Dehydro-beta-amino Acids for the Preparation of alpha-v-beta-3 and alpha-5-beta-1 Integrin Inhibitors 149
Dehydro-beta-amino acids as scaffolds for the preparation of alpha-v-beta-3, alpha-5-beta-1 and alpha-4-beta-1 integrin ligands 149
Linker Hydrophilicity Modulates the Anticancer Activity of RGD–Cryptophycin Conjugates 147
Easy preparation of dehydroalanine building blocks equipped with oxazolidin-2-one chiral auxiliaries, and applications to the stereoselective synthesis of substituted tryptophans 146
Totale 19.607
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Categoria #
all - tutte 71.211
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 71.211
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021447 0 0 0 0 0 0 0 0 0 0 0 447
2021/20222.705 343 155 186 132 262 146 95 294 107 148 409 428
2022/20233.089 264 447 156 382 224 261 119 161 592 91 236 156
2023/20241.376 91 135 80 119 169 284 101 98 43 99 83 74
2024/20254.123 192 599 379 241 767 250 401 118 37 252 133 754
2025/20268.333 634 775 697 597 897 471 951 257 1.697 599 401 357
Totale 26.339