CRIS Current Research Information System

GENTILUCCI, LUCA
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
NA - Nord America 9.399
AS - Asia 8.364
EU - Europa 7.438
AF - Africa 675
Continente sconosciuto - Info sul continente non disponibili 471
SA - Sud America 386
OC - Oceania 19
Totale 26.752
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 9.242
IT - Italia 2.493
CN - Cina 2.458
SG - Singapore 2.152
VN - Vietnam 2.001
GB - Regno Unito 1.463
DE - Germania 805
HK - Hong Kong 584
FR - Francia 478
SE - Svezia 387
UA - Ucraina 380
IN - India 341
RU - Federazione Russa 340
IE - Irlanda 265
BR - Brasile 256
NL - Olanda 217
TG - Togo 205
CI - Costa d'Avorio 188
JP - Giappone 158
KR - Corea 148
FI - Finlandia 143
ZA - Sudafrica 121
BD - Bangladesh 99
SC - Seychelles 94
CA - Canada 92
BG - Bulgaria 91
EE - Estonia 88
JO - Giordania 68
CH - Svizzera 58
PH - Filippine 57
AR - Argentina 45
ID - Indonesia 45
TH - Thailandia 41
BE - Belgio 39
ES - Italia 39
MX - Messico 33
TW - Taiwan 30
EC - Ecuador 29
HR - Croazia 28
IQ - Iraq 27
PK - Pakistan 27
NG - Nigeria 26
TR - Turchia 23
AT - Austria 22
PL - Polonia 20
IR - Iran 19
CO - Colombia 18
CL - Cile 17
LB - Libano 17
AU - Australia 16
RO - Romania 16
PT - Portogallo 13
UZ - Uzbekistan 12
GR - Grecia 10
CR - Costa Rica 9
JM - Giamaica 9
SA - Arabia Saudita 9
LT - Lituania 8
CZ - Repubblica Ceca 7
KZ - Kazakistan 7
MA - Marocco 7
PE - Perù 7
AE - Emirati Arabi Uniti 6
EU - Europa 6
IL - Israele 6
TN - Tunisia 6
VE - Venezuela 6
ET - Etiopia 5
PY - Paraguay 5
RS - Serbia 5
AZ - Azerbaigian 4
DZ - Algeria 4
EG - Egitto 4
HU - Ungheria 4
NP - Nepal 4
SI - Slovenia 4
AO - Angola 3
BH - Bahrain 3
KE - Kenya 3
MY - Malesia 3
NI - Nicaragua 3
NO - Norvegia 3
AL - Albania 2
BB - Barbados 2
BN - Brunei Darussalam 2
BZ - Belize 2
CY - Cipro 2
DK - Danimarca 2
DO - Repubblica Dominicana 2
KG - Kirghizistan 2
LV - Lettonia 2
ML - Mali 2
NZ - Nuova Zelanda 2
OM - Oman 2
SN - Senegal 2
UY - Uruguay 2
AG - Antigua e Barbuda 1
AM - Armenia 1
BA - Bosnia-Erzegovina 1
BO - Bolivia 1
Totale 26.266
Salva come PNG Salva come JPEG
Città #
Singapore 1.456
Southend 1.238
Ashburn 886
Fairfield 767
San Jose 632
Chandler 604
Santa Clara 552
Bologna 529
Hong Kong 521
Ho Chi Minh City 438
Hanoi 392
Woodbridge 375
Seattle 348
Wilmington 340
Hefei 335
Beijing 319
Princeton 300
Houston 293
Cambridge 285
Jacksonville 266
Dong Ket 264
Ann Arbor 263
Council Bluffs 248
Dublin 246
Lomé 205
Boardman 191
Abidjan 188
Milan 170
Lauterbourg 154
Nanjing 153
Los Angeles 145
Tokyo 134
Padova 130
Westminster 130
Seoul 121
Helsinki 116
Dallas 111
Berlin 104
Sofia 91
New York 88
Jinan 85
Shanghai 78
Buffalo 74
Rome 74
Guangzhou 73
Da Nang 71
Shenyang 70
Amman 68
Haiphong 65
Saint Petersburg 64
Bremen 61
Frankfurt am Main 58
Tianjin 58
Changsha 54
Turin 52
Hebei 49
Medford 48
Redondo Beach 47
Mülheim 46
San Diego 45
Zhengzhou 44
Chicago 42
Redmond 40
Hangzhou 39
Nanchang 39
Forlì 38
Brussels 36
Munich 36
São Paulo 36
Atlanta 31
Haikou 31
Wuhan 31
Des Moines 29
Phoenix 29
Bari 28
Bengaluru 27
Jakarta 27
Mountain View 27
Biên Hòa 25
Falkenstein 25
Mahé 25
Shenzhen 25
Yubileyny 25
Abeokuta 24
Cesena 24
Orem 24
Redwood City 24
Toronto 24
Florence 23
Modena 23
Verona 23
Jiaxing 21
The Dalles 21
London 20
Genoa 19
Las Vegas 19
Norwalk 19
Brooklyn 18
Denver 18
Kunming 18
Totale 16.465
Salva come PNG Salva come JPEG
Nome #
Inibitori dei processi infiammatori cronici connessi allo sviluppo di tumori (Inhibitors of the chronic inflammatory processes connected to tumor development) 829
Modern tools for the chemical ligation and synthesis of modified peptides and proteins 312
Targeting integrins αvβ3 and α5β1 with new β-lactam derivatives 297
Synthesis and Biological Evaluation of Nonpeptide alpha-v-beta-3/alpha-5-beta-1 Integrin Dual Antagonists containing 5,6-Dihydropyridin-2-one Scaffolds 279
Leukocyte Integrin Antagonists as a Novel Option to Treat Dry Age-Related Macular Degeneration 278
Dehydro-beta-proline Containing Alpha-4-beta-1 Integrin Antagonists: Stereochemical Recognition in Ligand-Receptor Interplay 275
Thixotropic peptide-based physical hydrogels applied to three-dimensional cell culture 273
Constraining Endomorphin-1 by β,α-Hybrid Dipeptide/Heterocycle Scaffolds: Identification of a Novel κ-Opioid Receptor Selective Partial Agonist 273
Design of κ-Opioid Receptor Agonists for the Development of Potential Treatments of Pain with Reduced Side Effects 256
Could Dissecting the Molecular Framework of β-Lactam Integrin Ligands Enhance Selectivity? 255
Conjecturing about Small-Molecule Agonists and Antagonists of α4β1 Integrin: From Mechanistic Insight to Potential Therapeutic Applications 249
Preparation of Non-Toxic Fluorescent Peptide-Coated Silica/PEG Nanoparticles from Peptide-Block Copolymer Conjugates 245
A novel family of minimal PMRI cyclic peptides as versatile scaffolds for generating new molecular topology. 242
Chemical Modifications Designed to Improve Peptide Stability: Incorporation of Non-Natural Amino Acids, Pseudo-Peptide Bonds, and Cyclization 238
5-aminomethyloxazolidine-2,4-dione hybrid α/β-dipeptide scaffolds as inductors of constrained conformations: Applications to the synthesis of integrin antagonists 238
A convenient synthesis of functionalized isoxazolines and related 5-hydroxy-isoxazolidine-4-carboxylates 229
A simple route towards peptide analogues containing substituted (S)- or (R)-tryptophans 222
DS-70, a novel and potent α4 integrin antagonist, is an effective treatment for experimental allergic conjunctivitis in guinea pigs 222
Synthesis and Antiproliferative Activity against Cancer Cells of Indole-Aryl-Amide Derivatives 217
Integrin-targeting dye-doped peg-shell/silica-core nanoparticles mimicking the proapoptotic Smac/DIABLO protein 217
Diagnostic implementation of fast and selective integrin-mediated adhesion of cancer cells on functionalized zeolite L monolayers 215
A microwave-enhanced, Lewis acid-catalyzed synthesis of 1,3-dioxolanes and oxazolines from epoxides 215
Practical synthesis of 3-bromo-5,6-dihydropyridin-2-ones via β,γ-unsaturated α-bromo-ketene/imine cycloaddition 213
alpha-Bromo-beta,gamma-unsaturated Ketenes as Valuable Intermediates in the Synthesis of alpha-Amino-beta,gamma-Unsaturated Acids 213
Highly Regio- and Diastereoselective Palladium-Catalyzed Allylic Substitution. Synthesis of 3-(2-aminobutylidene)-4-arylazetidin-2-ones 210
Functional Selectivity and Antinociceptive Effects of a Novel KOPr Agonist 210
Integrin Ligands with α/β-Hybrid Peptide Structure: Design, Bioactivity, and Conformational Aspects 209
A novel family of minimalist opioid peptides deprived of the classic pharmacophores 208
Antiangiogenic Effect of Dual/Selective α5β1/αvβ3 Integrin Antagonists Designed on Partially Modified Retro-Inverso Cyclotetrapeptide Mimetics 207
Ac-D-Trp-PheNH2 AND Ac-D-Trp-Phe-GlyNH2 - A NEW CLASS OF UNUSUAL OPIOID PEPTIDES 206
Green synthesis of bioactive oligopeptides promoted by recyclable nanocrystalline hydroxyapatite 204
Synthesis of mixed MOR/KOR efficacy cyclic opioid peptide analogs with antinociceptive activity after systemic administration 203
Peptide bond formation using unprotected N-carboxyanhydrides under green chemistry conditions 203
Pharmacological Characterization of µ-Opioid Receptor Agonists with Biased G Protein or β-Arrestin Signaling, and Computational Study of Conformational Changes during Receptor Activation 202
Design of α/β-hybrid peptide ligands of α4β1 integrin equipped with a linkable side chain for chemoselective biofunctionalization of microstructured materials 199
Controlling Cyclopeptide Backbone Conformation with β/α-Hybrid Peptide–Heterocycle Scaffolds 198
An investigation of the reactivity of MCPBA and alpha-bromoalkenes under traditional or microwave-assisted conditions: Selective formation of epoxides or allylic bromides. 196
Zinc Metal-Promoted Nucleophilic Addition of Azetidin-2-ones to Aldehydes and Nitriles 195
Exploring the reactivity of alkylidene malonamides: synthesis of polyfunctionalized isoxazolidinones, aziridines and oxazolines 194
Asymmetric Synthesis of three and four membered ring heterocycles 192
A straightforward route to enantiopure 2-substituted-3,4-dehydro-beta-proline via ring closing metathesis 191
An improved microwave assisted protocol for Yonemitsu-type trimolecular condensation 191
PacDOCK: A Web Server for Positional Distance-Based and Interaction-Based Analysis of Docking Results 191
Convenient Synthesis of the Antibiotic Linezolid via an Oxazolidine-2,4-dione Intermediate Derived from the Chiral Building Block Isoserine 189
Peptides inhibiting the assembly of monomeric human l‐lactate dehydrogenase into catalytically active homotetramer decrease the synthesis of lactate in cultured cells 188
New trends in the development of opioid peptide analogues as advanced remedies for pain relief 188
Synthesis and Biological Evaluation of Azido- and Aziridino-hydroxyl-beta -lactams through Stereo- and Regioselective Epoxide Ring Opening. 188
Synthesis and evaluation of the affinity toward mu-opioid receptor of atypical, lipophilic ligands based on the sequence c[Tyr-Pro-Trp-Phe-Gly-]. 187
The Inverse Type II β-Turn on D-Trp-Phe, a Pharmacophoric Motif for MOR Agonists. 187
Synthesis and assay of retro-α4β1 integrin-targeting motifs 186
Topological exploration of cyclic endomorphin-1 analogues, structurally defined models for investigating the bioactive conformation of MOR agonists. 185
Investigation of the Interaction Between the Atypical Agonist c[YpwFG] and MOR 185
Asymmetric Synthesis of Three and Four Membered Ring Heterocycles - Chapter 1 183
Controlled solid phase peptide bond formation using N-carboxyanhydrides and PEG resins in water. 183
Dehydro-beta-amino Acid Containing Peptides as Promising Sequences for Drug Development 182
DESIGN AND SYNTHESIS OF OPIOID PEPTIDE ANALOGUES AND MIMETICS 182
Modulation of αvβ3- and α5β1-integrin-mediated adhesion by dehydro-β-amino acids containing peptidomimetics 182
Identification of c[D-Trp-Phe-β-Ala-β-Ala], the First κ-Opioid Receptor-Specific Negative Allosteric Modulator 181
In-peptide synthesis of di-oxazolidinone and dehydroamino acid-oxazolidinone motifs as β-turn inducers 180
Design, Pharmacological Characterization, and Molecular Docking of Minimalist Peptidomimetic Antagonists of α4β1 Integrin 178
Opioid Activity Profiles of Oversimplified Peptides Lacking in the Protonable N-Terminus 178
Unusual Amino Acids: Synthesis and Introduction into Naturally Occurring Peptides and Biologically Active Analogues 174
Highly Diastereoselective Allylic Azide Formation and Isomerization. Synthesis of 3(2'-Amino)-beta-lactams 171
Design and Pharmacological Characterization of α4β1 Integrin Cyclopeptide Agonists: Computational Investigation of Ligand Determinants for Agonism versus Antagonism 169
Highly regio- and stereoselective palladium-catalyzed allylic carbonate amination. A practical route to dehydro-beta-amino esters 169
Expedient recycling of peptide organocatalysts using a nanocrystalline hydroxyapatite catching system 168
Cyclotetrapeptide Mimics based on a 13-Membered, Partially Modified Retro-Inverso Structure 168
Introduction of hydroxyl- or keto- functionalities into the side chain of azetidin-2-ones via allylic bromide rearrangement, followed by supported reagent substitution 167
One-Pot Synthesis of Poly-Substituted Tetramic Acids for the Preparation of Reverse-Turn Mimics 167
NEW PEPTIDOMIMETIC α4β1-INTEGRIN ANTAGONISTS FOR REDUCING INFLAMMATION AND ALLERGIC REACTIONS 167
Heterocyclic Scaffolds in the Design of Peptidomimetic Integrin Ligands: Synthetic Strategies, Structural Aspects, and Biological Activity 167
Peptide direct growth on poly(acrylic acid)/poly(vinyl alcohol) electrospun fibers coated with branched poly(ethylenimine): A solid-phase approach for scaffolds biofunctionalization 166
Peptides and peptidomimetics in medicine, surgery, and biotecnology 166
Synthesis of dehydro-beta-amino esters via highly regioselective amination of allylic carbonates 166
A new generation of opioid peptidomimetics acting as central and/or peripheral analgesics 165
Purification from Deinococcus radiodurans of a 66 kDa ABC transporter acting on peptides containing at least 3 amino acids 165
Functionalizations of the C3 side chain of densely substituted azetidin-2-ones 164
Selective detection of α4β1 integrin (VLA-4)-expressing cells using peptide-functionalized nanostructured materials mimicking endothelial surfaces adjacent to inflammatory sites 164
Inhibition of cancer cell adhesion by heterochiral Pro-containing RGD mimetics. 163
Cyclopeptide analogs for generating new molecular and 3D diversity 162
Lewis acid induced highly regioselective synthesis of a new class of substituted isoxazolidines 162
Enzymatic Resolution of Ethyl 3-Hydroxy-2(1'substituted-methylidene)-butyrate by Pseudomonas Cepacia Lipase Catalyzed Acetylation 162
Versatile Picklocks to Access All Opioid Receptors: Tuning the Selectivity and Functional Profile of the Cyclotetrapeptide c[Phe- d -Pro-Phe-Trp] (CJ-15,208) 161
Synthesis and Conformational Analysis of Cyclotetrapeptide Mimetic beta-Turn Templates and Validation as 3D Scaffolds 161
Stereoselective synthesis of a new class of spiro-beta-lactams via epoxide ring opening 160
Cyclic side-chain-linked opioid analogs utilizing cis- and trans-4-aminocyclohexyl-d-alanine 159
Stereoselective synthesis of a new class of spiro-beta-lactams via epoxide ring opening 157
Synthesis of chiral non-racemic intermediates and Arg-Gly-Asp mimetics by CaLB-catalyzed resolution 157
Molecular Docking of Opiates and Opioid Peptides, a Tool for the Design of Selective Agonists and Antagonists, and for the Investigation of Atypical Ligand-Receptor Interactions 157
Development of isoxazoline-containing peptidomimetics as dual alpha-v-beta-3 and alpha-5-beta-1 integrin ligands. 156
Integrin-targeting peptides for the design of functional cell-responsive biomaterials 155
Design and synthesis of Alpha-v-beta-3 and Alpha-5-beta-1 integrin ligands as delivery systems for fluorescent molecules 154
Design and characterization of opioid ligands based on cycle-in-macrocycle scaffold 154
Dehydro-beta-amino acids as scaffolds for the preparation of alpha-v-beta-3, alpha-5-beta-1 and alpha-4-beta-1 integrin ligands 153
Synthesis of Ethyl 5-Hydroxyisoxazolidine-4-carboxylates via Michael Addition/Intramolecular Hemiketalisation 153
DETERMINATION OF THE BIOLOGICALLY ACTIVE STRUCTURE OF THE ATYPICAL MOR-LIGAND c[D-Asp-1-amide-beta-Ala-D-Trp-Phe] AND ANALOGUES BY NMR AND MOLECULAR DOCKING 152
Stereoselective Synthesis of Linear and Cyclic Dehydro-beta-amino Acids for the Preparation of alpha-v-beta-3 and alpha-5-beta-1 Integrin Inhibitors 151
Easy preparation of dehydroalanine building blocks equipped with oxazolidin-2-one chiral auxiliaries, and applications to the stereoselective synthesis of substituted tryptophans 150
Synthesis of Enantiomerically Pure alpha-v-beta-3 Integrin ligands Based on a 5,6-Dihydropyridin-2-one Scaffold. 150
Linker Hydrophilicity Modulates the Anticancer Activity of RGD–Cryptophycin Conjugates 148
Totale 19.903
Salva come PNG Salva come JPEG
Categoria #
all - tutte 73.752
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 73.752
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20222.351 0 154 185 132 259 146 95 293 106 148 407 426
2022/20233.084 263 446 156 381 223 261 119 161 591 91 236 156
2023/20241.367 91 133 79 118 167 283 100 98 43 99 83 73
2024/20254.114 192 597 378 240 766 250 398 118 37 252 133 753
2025/20268.302 634 773 692 596 895 466 947 255 1.692 595 400 357
2026/2027498 244 254 0 0 0 0 0 0 0 0 0 0
Totale 26.752