CRIS Current Research Information System

GENTILUCCI, LUCA
 Distribuzione geografica
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Continente #
NA - Nord America 7.706
EU - Europa 6.802
AS - Asia 6.289
AF - Africa 645
SA - Sud America 327
OC - Oceania 14
Continente sconosciuto - Info sul continente non disponibili 6
Totale 21.789
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Nazione #
US - Stati Uniti d'America 7.632
CN - Cina 2.203
IT - Italia 2.184
SG - Singapore 1.939
GB - Regno Unito 1.461
VN - Vietnam 867
DE - Germania 781
HK - Hong Kong 507
SE - Svezia 387
UA - Ucraina 375
RU - Federazione Russa 338
FR - Francia 317
IN - India 300
IE - Irlanda 237
BR - Brasile 220
TG - Togo 205
NL - Olanda 192
CI - Costa d'Avorio 188
KR - Corea 125
ZA - Sudafrica 119
JP - Giappone 111
FI - Finlandia 98
BG - Bulgaria 91
SC - Seychelles 91
EE - Estonia 88
JO - Giordania 68
CH - Svizzera 56
CA - Canada 47
AR - Argentina 42
ID - Indonesia 40
BE - Belgio 37
ES - Italia 34
EC - Ecuador 27
HR - Croazia 25
NG - Nigeria 25
MX - Messico 21
AT - Austria 20
IR - Iran 19
PL - Polonia 17
LB - Libano 16
RO - Romania 16
TR - Turchia 16
CL - Cile 15
PK - Pakistan 15
CO - Colombia 13
AU - Australia 11
BD - Bangladesh 10
GR - Grecia 8
IQ - Iraq 8
PT - Portogallo 7
EU - Europa 6
LT - Lituania 6
CZ - Repubblica Ceca 5
IL - Israele 5
TW - Taiwan 5
UZ - Uzbekistan 5
AZ - Azerbaigian 4
HU - Ungheria 4
PE - Perù 4
PY - Paraguay 4
TH - Thailandia 4
TN - Tunisia 4
AE - Emirati Arabi Uniti 3
KZ - Kazakistan 3
MA - Marocco 3
NO - Norvegia 3
SI - Slovenia 3
AL - Albania 2
BH - Bahrain 2
BN - Brunei Darussalam 2
BZ - Belize 2
DK - Danimarca 2
DZ - Algeria 2
EG - Egitto 2
LV - Lettonia 2
NZ - Nuova Zelanda 2
PH - Filippine 2
AM - Armenia 1
AO - Angola 1
BA - Bosnia-Erzegovina 1
BB - Barbados 1
BO - Bolivia 1
BY - Bielorussia 1
CY - Cipro 1
DM - Dominica 1
DO - Repubblica Dominicana 1
ET - Etiopia 1
GE - Georgia 1
KE - Kenya 1
KG - Kirghizistan 1
KI - Kiribati 1
LA - Repubblica Popolare Democratica del Laos 1
LI - Liechtenstein 1
LK - Sri Lanka 1
MK - Macedonia 1
ML - Mali 1
MW - Malawi 1
NP - Nepal 1
OM - Oman 1
RS - Serbia 1
Totale 21.783
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Città #
Singapore 1.282
Southend 1.248
Ashburn 788
Fairfield 768
Chandler 604
Santa Clara 529
Hong Kong 484
Bologna 476
Woodbridge 375
Seattle 343
Wilmington 339
Hefei 334
Princeton 300
Beijing 294
Houston 287
Cambridge 285
Ann Arbor 265
Dong Ket 264
Jacksonville 262
Dublin 226
Lomé 205
Abidjan 188
Boardman 186
Nanjing 153
Ho Chi Minh City 147
Milan 147
Padova 131
Westminster 131
Seoul 119
Los Angeles 115
Hanoi 112
Tokyo 105
Berlin 98
Dallas 97
Sofia 91
Jinan 85
Helsinki 73
Amman 68
Shenyang 68
Buffalo 67
Saint Petersburg 64
New York 63
Bremen 61
Shanghai 61
Guangzhou 59
Changsha 51
Hebei 50
Tianjin 50
Medford 49
Redondo Beach 47
Rome 47
Mülheim 46
San Diego 45
Frankfurt am Main 44
Turin 44
Zhengzhou 42
Redmond 40
Nanchang 39
Munich 36
Brussels 35
Hangzhou 35
Haikou 31
Chicago 28
Des Moines 27
Mountain View 27
Wuhan 27
Bengaluru 26
Phoenix 26
São Paulo 26
Falkenstein 25
Jakarta 25
Mahé 25
Yubileyny 25
Abeokuta 24
Cesena 24
Redwood City 24
San Jose 24
Bari 23
Forlì 23
Haiphong 23
Toronto 21
Florence 20
Modena 20
Jiaxing 19
Norwalk 19
Verona 19
Zurich 18
Falls Church 17
Ningbo 17
Nuremberg 17
Shenzhen 17
Atlanta 16
Boydton 16
Chengdu 16
Forlimpopoli 16
Kunming 16
London 16
Pessac 16
San Mauro Pascoli 16
San Venanzo 15
Totale 13.977
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Nome #
Inibitori dei processi infiammatori cronici connessi allo sviluppo di tumori (Inhibitors of the chronic inflammatory processes connected to tumor development) 723
Targeting integrins αvβ3 and α5β1 with new β-lactam derivatives 254
Synthesis and Biological Evaluation of Nonpeptide alpha-v-beta-3/alpha-5-beta-1 Integrin Dual Antagonists containing 5,6-Dihydropyridin-2-one Scaffolds 249
Leukocyte Integrin Antagonists as a Novel Option to Treat Dry Age-Related Macular Degeneration 232
Dehydro-beta-proline Containing Alpha-4-beta-1 Integrin Antagonists: Stereochemical Recognition in Ligand-Receptor Interplay 230
Constraining Endomorphin-1 by β,α-Hybrid Dipeptide/Heterocycle Scaffolds: Identification of a Novel κ-Opioid Receptor Selective Partial Agonist 224
Modern tools for the chemical ligation and synthesis of modified peptides and proteins 223
A novel family of minimal PMRI cyclic peptides as versatile scaffolds for generating new molecular topology. 221
Thixotropic peptide-based physical hydrogels applied to three-dimensional cell culture 218
5-aminomethyloxazolidine-2,4-dione hybrid α/β-dipeptide scaffolds as inductors of constrained conformations: Applications to the synthesis of integrin antagonists 206
Chemical Modifications Designed to Improve Peptide Stability: Incorporation of Non-Natural Amino Acids, Pseudo-Peptide Bonds, and Cyclization 201
Design of κ-Opioid Receptor Agonists for the Development of Potential Treatments of Pain with Reduced Side Effects 199
A simple route towards peptide analogues containing substituted (S)- or (R)-tryptophans 198
A convenient synthesis of functionalized isoxazolines and related 5-hydroxy-isoxazolidine-4-carboxylates 196
Practical synthesis of 3-bromo-5,6-dihydropyridin-2-ones via β,γ-unsaturated α-bromo-ketene/imine cycloaddition 194
DS-70, a novel and potent α4 integrin antagonist, is an effective treatment for experimental allergic conjunctivitis in guinea pigs 193
A novel family of minimalist opioid peptides deprived of the classic pharmacophores 191
A microwave-enhanced, Lewis acid-catalyzed synthesis of 1,3-dioxolanes and oxazolines from epoxides 189
Could Dissecting the Molecular Framework of β-Lactam Integrin Ligands Enhance Selectivity? 187
Preparation of Non-Toxic Fluorescent Peptide-Coated Silica/PEG Nanoparticles from Peptide-Block Copolymer Conjugates 185
alpha-Bromo-beta,gamma-unsaturated Ketenes as Valuable Intermediates in the Synthesis of alpha-Amino-beta,gamma-Unsaturated Acids 183
Ac-D-Trp-PheNH2 AND Ac-D-Trp-Phe-GlyNH2 - A NEW CLASS OF UNUSUAL OPIOID PEPTIDES 183
Highly Regio- and Diastereoselective Palladium-Catalyzed Allylic Substitution. Synthesis of 3-(2-aminobutylidene)-4-arylazetidin-2-ones 182
Conjecturing about Small-Molecule Agonists and Antagonists of α4β1 Integrin: From Mechanistic Insight to Potential Therapeutic Applications 180
Antiangiogenic Effect of Dual/Selective α5β1/αvβ3 Integrin Antagonists Designed on Partially Modified Retro-Inverso Cyclotetrapeptide Mimetics 179
Functional Selectivity and Antinociceptive Effects of a Novel KOPr Agonist 174
Synthesis and evaluation of the affinity toward mu-opioid receptor of atypical, lipophilic ligands based on the sequence c[Tyr-Pro-Trp-Phe-Gly-]. 173
Integrin-targeting dye-doped peg-shell/silica-core nanoparticles mimicking the proapoptotic Smac/DIABLO protein 173
An improved microwave assisted protocol for Yonemitsu-type trimolecular condensation 172
Exploring the reactivity of alkylidene malonamides: synthesis of polyfunctionalized isoxazolidinones, aziridines and oxazolines 171
Green synthesis of bioactive oligopeptides promoted by recyclable nanocrystalline hydroxyapatite 171
New trends in the development of opioid peptide analogues as advanced remedies for pain relief 170
Zinc Metal-Promoted Nucleophilic Addition of Azetidin-2-ones to Aldehydes and Nitriles 169
Controlling Cyclopeptide Backbone Conformation with β/α-Hybrid Peptide–Heterocycle Scaffolds 169
Diagnostic implementation of fast and selective integrin-mediated adhesion of cancer cells on functionalized zeolite L monolayers 168
Convenient Synthesis of the Antibiotic Linezolid via an Oxazolidine-2,4-dione Intermediate Derived from the Chiral Building Block Isoserine 168
Asymmetric Synthesis of three and four membered ring heterocycles 167
Synthesis of mixed MOR/KOR efficacy cyclic opioid peptide analogs with antinociceptive activity after systemic administration 167
A straightforward route to enantiopure 2-substituted-3,4-dehydro-beta-proline via ring closing metathesis 166
Integrin Ligands with α/β-Hybrid Peptide Structure: Design, Bioactivity, and Conformational Aspects 166
Synthesis and Antiproliferative Activity against Cancer Cells of Indole-Aryl-Amide Derivatives 164
An investigation of the reactivity of MCPBA and alpha-bromoalkenes under traditional or microwave-assisted conditions: Selective formation of epoxides or allylic bromides. 163
Pharmacological Characterization of µ-Opioid Receptor Agonists with Biased G Protein or β-Arrestin Signaling, and Computational Study of Conformational Changes during Receptor Activation 163
Synthesis and Biological Evaluation of Azido- and Aziridino-hydroxyl-beta -lactams through Stereo- and Regioselective Epoxide Ring Opening. 160
Topological exploration of cyclic endomorphin-1 analogues, structurally defined models for investigating the bioactive conformation of MOR agonists. 160
The Inverse Type II β-Turn on D-Trp-Phe, a Pharmacophoric Motif for MOR Agonists. 159
Design of α/β-hybrid peptide ligands of α4β1 integrin equipped with a linkable side chain for chemoselective biofunctionalization of microstructured materials 159
Dehydro-beta-amino Acid Containing Peptides as Promising Sequences for Drug Development 158
Opioid Activity Profiles of Oversimplified Peptides Lacking in the Protonable N-Terminus 158
DESIGN AND SYNTHESIS OF OPIOID PEPTIDE ANALOGUES AND MIMETICS 158
Unusual Amino Acids: Synthesis and Introduction into Naturally Occurring Peptides and Biologically Active Analogues 156
Asymmetric Synthesis of Three and Four Membered Ring Heterocycles - Chapter 1 155
Synthesis and assay of retro-α4β1 integrin-targeting motifs 155
Modulation of αvβ3- and α5β1-integrin-mediated adhesion by dehydro-β-amino acids containing peptidomimetics 155
Highly Diastereoselective Allylic Azide Formation and Isomerization. Synthesis of 3(2'-Amino)-beta-lactams 154
Peptide bond formation using unprotected N-carboxyanhydrides under green chemistry conditions 154
Investigation of the Interaction Between the Atypical Agonist c[YpwFG] and MOR 152
A new generation of opioid peptidomimetics acting as central and/or peripheral analgesics 150
Inhibition of cancer cell adhesion by heterochiral Pro-containing RGD mimetics. 150
Highly regio- and stereoselective palladium-catalyzed allylic carbonate amination. A practical route to dehydro-beta-amino esters 148
Peptides and peptidomimetics in medicine, surgery, and biotecnology 147
PacDOCK: A Web Server for Positional Distance-Based and Interaction-Based Analysis of Docking Results 147
Lewis acid induced highly regioselective synthesis of a new class of substituted isoxazolidines 145
Enzymatic Resolution of Ethyl 3-Hydroxy-2(1'substituted-methylidene)-butyrate by Pseudomonas Cepacia Lipase Catalyzed Acetylation 145
Controlled solid phase peptide bond formation using N-carboxyanhydrides and PEG resins in water. 145
Synthesis of dehydro-beta-amino esters via highly regioselective amination of allylic carbonates 144
Cyclotetrapeptide Mimics based on a 13-Membered, Partially Modified Retro-Inverso Structure 144
In-peptide synthesis of di-oxazolidinone and dehydroamino acid-oxazolidinone motifs as β-turn inducers 144
Stereoselective synthesis of a new class of spiro-beta-lactams via epoxide ring opening 143
Cyclopeptide analogs for generating new molecular and 3D diversity 142
Heterocyclic Scaffolds in the Design of Peptidomimetic Integrin Ligands: Synthetic Strategies, Structural Aspects, and Biological Activity 140
Molecular Docking of Opiates and Opioid Peptides, a Tool for the Design of Selective Agonists and Antagonists, and for the Investigation of Atypical Ligand-Receptor Interactions 140
Peptides inhibiting the assembly of monomeric human l‐lactate dehydrogenase into catalytically active homotetramer decrease the synthesis of lactate in cultured cells 139
Peptide direct growth on poly(acrylic acid)/poly(vinyl alcohol) electrospun fibers coated with branched poly(ethylenimine): A solid-phase approach for scaffolds biofunctionalization 137
Functionalizations of the C3 side chain of densely substituted azetidin-2-ones 137
Stereoselective synthesis of a new class of spiro-beta-lactams via epoxide ring opening 137
Development of isoxazoline-containing peptidomimetics as dual alpha-v-beta-3 and alpha-5-beta-1 integrin ligands. 137
Identification of c[D-Trp-Phe-β-Ala-β-Ala], the First κ-Opioid Receptor-Specific Negative Allosteric Modulator 136
Introduction of hydroxyl- or keto- functionalities into the side chain of azetidin-2-ones via allylic bromide rearrangement, followed by supported reagent substitution 136
Cyclic side-chain-linked opioid analogs utilizing cis- and trans-4-aminocyclohexyl-d-alanine 135
Synthesis of Ethyl 5-Hydroxyisoxazolidine-4-carboxylates via Michael Addition/Intramolecular Hemiketalisation 134
DETERMINATION OF THE BIOLOGICALLY ACTIVE STRUCTURE OF THE ATYPICAL MOR-LIGAND c[D-Asp-1-amide-beta-Ala-D-Trp-Phe] AND ANALOGUES BY NMR AND MOLECULAR DOCKING 133
Versatile Picklocks to Access All Opioid Receptors: Tuning the Selectivity and Functional Profile of the Cyclotetrapeptide c[Phe- d -Pro-Phe-Trp] (CJ-15,208) 133
Dehydro-beta-amino acids as scaffolds for the preparation of alpha-v-beta-3, alpha-5-beta-1 and alpha-4-beta-1 integrin ligands 132
NEW PEPTIDOMIMETIC α4β1-INTEGRIN ANTAGONISTS FOR REDUCING INFLAMMATION AND ALLERGIC REACTIONS 132
Design and characterization of opioid ligands based on cycle-in-macrocycle scaffold 132
Purification from Deinococcus radiodurans of a 66 kDa ABC transporter acting on peptides containing at least 3 amino acids 132
Expedient recycling of peptide organocatalysts using a nanocrystalline hydroxyapatite catching system 131
Synthesis of chiral non-racemic intermediates and Arg-Gly-Asp mimetics by CaLB-catalyzed resolution 131
Synthesis and Conformational Analysis of Cyclotetrapeptide Mimetic beta-Turn Templates and Validation as 3D Scaffolds 131
One-Pot Synthesis of Poly-Substituted Tetramic Acids for the Preparation of Reverse-Turn Mimics 130
Design and synthesis of Alpha-v-beta-3 and Alpha-5-beta-1 integrin ligands as delivery systems for fluorescent molecules 129
Selective detection of α4β1 integrin (VLA-4)-expressing cells using peptide-functionalized nanostructured materials mimicking endothelial surfaces adjacent to inflammatory sites 129
Design and Pharmacological Characterization of α4β1 Integrin Cyclopeptide Agonists: Computational Investigation of Ligand Determinants for Agonism versus Antagonism 127
Stereoselective Synthesis of Linear and Cyclic Dehydro-beta-amino Acids for the Preparation of alpha-v-beta-3 and alpha-5-beta-1 Integrin Inhibitors 127
Synthesis of Enantiomerically Pure alpha-v-beta-3 Integrin ligands Based on a 5,6-Dihydropyridin-2-one Scaffold. 126
Design, Pharmacological Characterization, and Molecular Docking of Minimalist Peptidomimetic Antagonists of α4β1 Integrin 125
Synthesis of four-membered ring spiro-beta -lactams by epoxide ring-opening. 122
Easy preparation of dehydroalanine building blocks equipped with oxazolidin-2-one chiral auxiliaries, and applications to the stereoselective synthesis of substituted tryptophans 122
Integrin-targeting peptides for the design of functional cell-responsive biomaterials 122
Totale 16.695
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Categoria #
all - tutte 62.430
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 62.430
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20211.251 0 0 0 0 0 0 146 170 229 125 134 447
2021/20222.705 343 155 186 132 262 146 95 294 107 148 409 428
2022/20233.089 264 447 156 382 224 261 119 161 592 91 236 156
2023/20241.376 91 135 80 119 169 284 101 98 43 99 83 74
2024/20254.123 192 599 379 241 767 250 401 118 37 252 133 754
2025/20264.205 634 775 697 597 897 471 134 0 0 0 0 0
Totale 22.211