CRIS Current Research Information System

FALCHI, FEDERICO
 Distribuzione geografica
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Continente #
NA - Nord America 2.247
AS - Asia 2.022
EU - Europa 1.750
SA - Sud America 205
AF - Africa 149
OC - Oceania 33
Continente sconosciuto - Info sul continente non disponibili 1
Totale 6.407
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Nazione #
US - Stati Uniti d'America 2.209
SG - Singapore 662
IT - Italia 656
CN - Cina 618
GB - Regno Unito 252
HK - Hong Kong 208
SE - Svezia 179
BR - Brasile 171
DE - Germania 171
VN - Vietnam 168
IN - India 112
KR - Corea 110
FR - Francia 74
RU - Federazione Russa 69
NL - Olanda 68
IE - Irlanda 58
CI - Costa d'Avorio 45
JP - Giappone 44
BG - Bulgaria 38
TG - Togo 35
ZA - Sudafrica 32
AU - Australia 31
UA - Ucraina 28
NG - Nigeria 23
CH - Svizzera 21
EE - Estonia 21
PL - Polonia 21
AT - Austria 18
CA - Canada 18
ES - Italia 18
FI - Finlandia 17
MX - Messico 15
AR - Argentina 14
PK - Pakistan 13
JO - Giordania 12
TR - Turchia 11
TW - Taiwan 10
BD - Bangladesh 8
BE - Belgio 8
ID - Indonesia 8
MY - Malesia 7
GR - Grecia 6
IR - Iran 6
IQ - Iraq 5
LT - Lituania 5
CZ - Repubblica Ceca 4
EC - Ecuador 4
HR - Croazia 4
SC - Seychelles 4
VE - Venezuela 4
AE - Emirati Arabi Uniti 3
BY - Bielorussia 3
CO - Colombia 3
IL - Israele 3
MA - Marocco 3
NP - Nepal 3
PY - Paraguay 3
UY - Uruguay 3
DK - Danimarca 2
EG - Egitto 2
JM - Giamaica 2
LB - Libano 2
LV - Lettonia 2
MU - Mauritius 2
RO - Romania 2
UZ - Uzbekistan 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AL - Albania 1
BA - Bosnia-Erzegovina 1
BO - Bolivia 1
BZ - Belize 1
CL - Cile 1
DZ - Algeria 1
GT - Guatemala 1
HN - Honduras 1
HU - Ungheria 1
KE - Kenya 1
KG - Kirghizistan 1
KZ - Kazakistan 1
LA - Repubblica Popolare Democratica del Laos 1
LK - Sri Lanka 1
NC - Nuova Caledonia 1
NZ - Nuova Zelanda 1
PE - Perù 1
PH - Filippine 1
PS - Palestinian Territory 1
PT - Portogallo 1
SA - Arabia Saudita 1
SM - San Marino 1
SN - Senegal 1
Totale 6.407
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Città #
Singapore 419
Ashburn 289
Bologna 218
Fairfield 199
Southend 199
Hong Kong 196
Hefei 192
Chandler 180
Santa Clara 136
Seattle 113
Woodbridge 110
Seoul 96
Houston 91
Wilmington 83
Beijing 74
Cambridge 72
Ann Arbor 65
Dublin 59
Milan 58
Boardman 52
Abidjan 45
Princeton 45
Ho Chi Minh City 35
Lomé 35
Los Angeles 35
Sofia 35
Dong Ket 34
New York 34
Buffalo 32
Verona 31
Berlin 29
Tokyo 27
Hanoi 26
Redmond 26
São Paulo 26
Sydney 25
Nanjing 24
Abeokuta 20
Westminster 20
Dallas 19
Bengaluru 18
Florence 17
Padova 17
Redondo Beach 17
Munich 16
Rome 16
Chicago 14
Mumbai 14
Amsterdam 13
Jacksonville 13
Warsaw 13
Amman 12
Frankfurt am Main 12
Johannesburg 12
Saint Petersburg 12
San Diego 12
Genoa 11
Guangzhou 11
Shenyang 11
Jhelum 10
Jinan 10
Nanchang 10
Nuremberg 10
Shanghai 10
Vienna 10
Zurich 10
Belo Horizonte 9
Council Bluffs 9
Hangzhou 9
Boston 8
Brooklyn 8
Brussels 8
Claymont 8
Falkenstein 8
Naples 8
San Francisco 8
Stockholm 8
Atlanta 7
Bern 7
Chennai 7
Falls Church 7
Helsinki 7
Jiaxing 7
Modena 7
Pesaro 7
Quartu Sant'Elena 7
Tianjin 7
Tongling 7
Toronto 7
Treviso 7
Turin 7
Bremen 6
Bühl 6
Goiânia 6
Lappeenranta 6
London 6
Montreal 6
Nagoya 6
Nijmegen 6
Phoenix 6
Totale 4.078
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Nome #
Probing allosteric communication with combined molecular dynamics simulations and network analysis 362
Design and synthesis of small molecules targeting pre-miRNA21 toward the development of ribonuclease targeting chimeras (RIBOTACs) to regulate the oncogenic miRNA21 252
Rad51/Brca2 Disruptors Inhibit Homologous Recombination and Synergize with Olaparib in Pancreatic Cancer Cells 239
Synthetic Lethality in Pancreatic Cancer: Discovery of a New RAD51-BRCA2 Small Molecule Disruptor That Inhibits Homologous Recombination and Synergizes with Olaparib 239
Multitarget Strategy to Address Alzheimer's Disease: Design, Synthesis, Biological Evaluation, and Computational Studies of Coumarin-Based Derivatives 233
2-Phenoxy-1,4-naphthoquinones: From a Multitarget Antitrypanosomal to a Potential Antitumor Profile 207
Protein Tunnels: The Case of Urease Accessory Proteins 188
Collecting and assessing human lactate dehydrogenase-A conformations for structure-based virtual screening 173
Synthetic Lethality Triggered by Combining Olaparib with BRCA2-Rad51 Disruptors 167
Synthesis of natural urolithin M6, a galloflavin mimetic, as a potential inhibitor of lactate dehydrogenase A 158
Targeting the Protein Tunnels of the Urease Accessory Complex: A Theoretical Investigation 157
Novel antiproliferative chimeric compounds with marked histone deacetylase inhibitory activity. 155
Pharmacological Inhibition of the Ubiquitin Ligase RNF5 Rescues F508del-CFTR in Cystic Fibrosis Airway Epithelia 148
Searching for New Microbiome-Targeted Therapeutics through a Drug Repurposing Approach 148
Discovery of Multitarget Agents Active as Broad-Spectrum Antivirals and Correctors of Cystic Fibrosis Transmembrane Conductance Regulator for Associated Pulmonary Diseases 144
Kernel-Based, Partial Least Squares Quantitative Structure-Retention Relationship Model for UPLC Retention Time Prediction: A Useful Tool for Metabolite Identification 143
Differential enantiomers activity of ARN24089 to achieve synthetic lethality in pancreatic cancer 141
Investigating synthetic lethality and PARP inhibitor resistance in pancreatic cancer through enantiomer differential activity 141
Discovery and SAR of 1,3,4-thiadiazole derivatives as potent Abl tyrosine kinase inhibitors and cytodifferentiating agents. 141
Design and synthesis of RAD51-BRCA2 protein-protein interaction disruptors to trigger synthetic lethality with Olaparib in pancreatic cancer cells 135
Innovative Strategy toward Mutant CFTR Rescue in Cystic Fibrosis: Design and Synthesis of Thiadiazole Inhibitors of the E3 Ligase RNF5 135
Targeting RNA degradation with small molecules: design and synthesis of selective RNA binders and development of ribonuclease targeting chimeras (RIBOTACs) 134
null 123
Proteostasis Regulators in Cystic Fibrosis: Current Development and Future Perspectives 123
null 121
Protein Dynamics of the HIF-2α PAS-B Domain upon Heterodimerization and Ligand Binding 120
null 118
Structure-based targeting of the lipid A-modifying enzyme PmrC to contrast colistin resistance in Acinetobacter baumannii 114
Structure-based design of small-molecule protein–protein interaction modulators: the story so far 106
Identification of N-acylhydrazone derivatives as novel lactate dehydrogenase A inhibitors 102
null 101
N-(thiazol-2-yl)-2-thiophene carboxamide derivatives as Abl inhibitors identified by a pharmacophore-based database screening of commercially available compounds 97
Chalcone-based carbamates for Alzheimer's disease treatment 96
Development of a multisite model for Ni(II) ion in solution from thermodynamic and kinetic data 96
null 95
null 89
Crassiflorone derivatives that inhibit Trypanosoma brucei glyceraldehyde-3-phosphate dehydrogenase (TbGAPDH) and Trypanosoma cruzi trypanothione reductase (TcTR) and display trypanocidal activity 85
A combined targeted/phenotypic approach for the identification of new antiangiogenics agents active on a zebrafish model: From in silico screening to cyclodextrin formulation 75
Triggering RNA degradation with small molecules: development of RIBOnuclease TArgeting Chimeras (RIBOTACs) 73
Divide et impera: An in silico screening targeting hcmv ppul44 processivity factor homodimerization identifies small molecules inhibiting viral replication 64
TARGETING RAD52 FOR SYNTHETIC LETHALITY: DISCOVERY OF A NOVEL SMALL MOLECULE AS A PROMISING INHIBITOR FOR CANCER THERAPY 59
IN SEARCH OF SMALL MOLECULES TARGETING RAD52 FOR SYNTHETIC LETHALITY 54
DESIGN AND SYNTHESIS OF SMALL MOLECULES TARGETING PRE-MIRNA21 TOWARD THE DEVELOPMENT OF RIBONUCLEASE TARGETING CHIMERAS (RIBOTACS) TO REGULATE THE ONCOGENIC MIRNA21 46
Structure-based virtual screening allows the identification of efficient modulators of E-cadherin-mediated cell-cell adhesion 45
Target Identification with Live-Cell Photoaffinity Labeling and Mechanism of Action Elucidation of ARN23765, a Highly Potent CFTR Corrector 44
Exploration of the Neuromodulatory Properties of Fyn and GSK-3β Kinases Exploiting 7-Azaindole-Based Inhibitors 44
COMPOUNDS WITH DDX3 INHIBITORY ACTIVITY AND USES THEREOF 43
NOVEL INHIBITORS OF PVHL-ELONGIN C BINDING 42
NON PEPTIDIC 14-3-3 INHIBITORS AND THE USE THEREOF 35
3D QSAR models built on structure-based alignments of Abl tyrosine kinase inhibitors 35
Discovery of the first small molecule inhibitor of human DDX3 specifically designed to target the RNA binding site: Towards the next generation HIV-1 inhibitors 34
Studies on the ATP Binding Site of Fyn Kinase for the Identification of New Inhibitors and Their Evaluation as Potential Agents against Tauopathies and Tumors 32
Computational techniques are valuable tools for the discovery of protein-protein interaction inhibitors: the 14-3-3σ case 30
Inhibitors of human immunodeficiency virus-1 replication targeting the human DEAD-box polypeptide 3 (DDX3) RNA helicase 30
Fyn kinase in brain diseases and cancer: The search for inhibitors 29
Identification of Hck Inhibitors As Hits for the Development of Antileukemia and Anti-HIV Agents 27
Determination of permeability and lipophilicity of pyrazolo-pyrimidine tyrosine kinase inhibitors and correlation with biological data 26
Design and synthesis of BRCA2-RAD51 disruptors to induce synthetic lethality in anticancer therapy 26
Targeting the human DEAD-box polypeptide 3 (DDX3) RNA helicase as a novel strategy to inhibit viral replication 25
Next generation of antiretroviral agents targeting the RNA binding site of the HIV-1 cellular cofactor DDX3: an innovative therapeutic approach 24
Design and synthesis of thiadiazoles and thiazoles targeting the Bcr-Abl T315I mutant: From docking false positives to ATP-noncompetitive inhibitors 24
Pharmacophore modeling and molecular docking led to the discovery of inhibitors of human immunodeficiency virus-1 replication targeting the human cellular aspartic acid-glutamic acid-alanine-aspartic acid box polypeptide 3 22
N-[2-methyl-5-(triazol-1-yl)phenyl]pyrimidin-2-amine as a Scaffold for the synthesis of inhibitors of Bcr-Abl 19
Toward the Discovery of Novel Anti-HIV Drugs. Second-Generation Inhibitors of the Cellular ATPase DDX3 with Improved Anti-HIV Activity: Synthesis, Structure-Activity Relationship Analysis, Cytotoxicity Studies, and Target Validation 18
Morphological inhibitors of aggregation-prone amyloid-β conformers: A computational exploration 6
Totale 6.557
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Categoria #
all - tutte 17.332
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 17.332
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021270 0 0 0 0 0 53 19 13 65 24 14 82
2021/2022548 47 5 37 17 45 29 14 90 25 35 110 94
2022/2023768 59 130 52 84 85 40 36 52 111 42 31 46
2023/2024304 11 51 15 22 16 57 9 34 9 34 29 17
2024/20251.447 35 114 75 82 199 37 112 54 38 144 170 387
2025/20262.071 372 383 329 420 379 188 0 0 0 0 0 0
Totale 6.557