CRIS Current Research Information System

FALCHI, FEDERICO
 Distribuzione geografica
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Continente #
AS - Asia 3.093
NA - Nord America 3.061
EU - Europa 2.285
SA - Sud America 259
AF - Africa 180
Continente sconosciuto - Info sul continente non disponibili 171
OC - Oceania 38
Totale 9.087
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Nazione #
US - Stati Uniti d'America 2.973
IT - Italia 1.030
SG - Singapore 805
CN - Cina 763
VN - Vietnam 586
HK - Hong Kong 270
GB - Regno Unito 269
BR - Brasile 201
SE - Svezia 182
DE - Germania 181
IN - India 141
BD - Bangladesh 138
KR - Corea 122
FR - Francia 120
JP - Giappone 86
NL - Olanda 76
RU - Federazione Russa 69
IE - Irlanda 59
CI - Costa d'Avorio 46
ZA - Sudafrica 44
CA - Canada 42
BG - Bulgaria 38
ES - Italia 35
TG - Togo 35
AU - Australia 34
UA - Ucraina 31
FI - Finlandia 30
CH - Svizzera 25
MX - Messico 25
PL - Polonia 25
NG - Nigeria 23
PK - Pakistan 23
AR - Argentina 22
AT - Austria 21
EE - Estonia 21
IQ - Iraq 21
JO - Giordania 18
TW - Taiwan 18
DK - Danimarca 16
PH - Filippine 16
TR - Turchia 16
ID - Indonesia 12
HR - Croazia 11
MY - Malesia 10
TH - Thailandia 10
GR - Grecia 9
BE - Belgio 8
EG - Egitto 8
VE - Venezuela 7
HN - Honduras 6
IR - Iran 6
JM - Giamaica 6
MA - Marocco 6
CL - Cile 5
CO - Colombia 5
CZ - Repubblica Ceca 5
EC - Ecuador 5
LT - Lituania 5
NP - Nepal 5
SC - Seychelles 5
UZ - Uzbekistan 5
AE - Emirati Arabi Uniti 4
BO - Bolivia 4
BY - Bielorussia 4
ET - Etiopia 4
IL - Israele 4
PY - Paraguay 4
SA - Arabia Saudita 4
CR - Costa Rica 3
HU - Ungheria 3
LV - Lettonia 3
NZ - Nuova Zelanda 3
PT - Portogallo 3
SN - Senegal 3
UY - Uruguay 3
DZ - Algeria 2
GT - Guatemala 2
KZ - Kazakistan 2
LB - Libano 2
MU - Mauritius 2
PE - Perù 2
RO - Romania 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AL - Albania 1
BA - Bosnia-Erzegovina 1
BZ - Belize 1
CG - Congo 1
GF - Guiana Francese 1
KE - Kenya 1
KG - Kirghizistan 1
LA - Repubblica Popolare Democratica del Laos 1
LK - Sri Lanka 1
MD - Moldavia 1
MM - Myanmar 1
NC - Nuova Caledonia 1
NI - Nicaragua 1
OM - Oman 1
PS - Palestinian Territory 1
SM - San Marino 1
TC - Turks e Caicos 1
Totale 8.916
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Città #
Singapore 552
Ashburn 361
Bologna 287
Hong Kong 240
Fairfield 199
Southend 199
Hefei 193
San Jose 190
Chandler 180
Santa Clara 158
Ho Chi Minh City 136
Hanoi 124
Seattle 113
Woodbridge 110
Council Bluffs 98
Seoul 96
Houston 95
Wilmington 83
Beijing 82
Milan 80
Cambridge 73
New York 70
Ann Arbor 65
Los Angeles 64
Tokyo 62
Dublin 61
Boardman 54
Abidjan 46
Princeton 45
Buffalo 44
Lauterbourg 44
Rome 38
Florence 37
São Paulo 36
Lomé 35
Sofia 35
Dong Ket 34
Verona 33
Berlin 29
Sydney 27
Redmond 26
Da Nang 25
Dallas 24
Nanjing 24
Johannesburg 22
Frankfurt am Main 21
Abeokuta 20
Chicago 20
Guangzhou 20
Haiphong 20
Westminster 20
Bengaluru 19
Calcinelli 19
Naples 19
Genoa 18
Shanghai 18
Helsinki 17
Padova 17
Redondo Beach 17
Amman 16
Jacksonville 16
Munich 16
Amsterdam 15
Mumbai 15
San Diego 14
Warsaw 14
London 13
Modena 13
Phoenix 13
Rimini 13
Toronto 13
Vienna 13
Chennai 12
Columbus 12
Montreal 12
Saint Petersburg 12
San Francisco 12
Atlanta 11
Baghdad 11
Copenhagen 11
Mexico City 11
Nanchang 11
Nuremberg 11
Shenyang 11
Boston 10
Hangzhou 10
Jhelum 10
Jinan 10
Zurich 10
Belo Horizonte 9
Orem 9
Stockholm 9
Brooklyn 8
Brussels 8
Claymont 8
Falkenstein 8
Lappeenranta 8
Tianjin 8
Bern 7
Denver 7
Totale 5.354
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Nome #
Probing allosteric communication with combined molecular dynamics simulations and network analysis 444
Design and synthesis of small molecules targeting pre-miRNA21 toward the development of ribonuclease targeting chimeras (RIBOTACs) to regulate the oncogenic miRNA21 391
2-Phenoxy-1,4-naphthoquinones: From a Multitarget Antitrypanosomal to a Potential Antitumor Profile 331
Multitarget Strategy to Address Alzheimer's Disease: Design, Synthesis, Biological Evaluation, and Computational Studies of Coumarin-Based Derivatives 299
Synthetic Lethality in Pancreatic Cancer: Discovery of a New RAD51-BRCA2 Small Molecule Disruptor That Inhibits Homologous Recombination and Synergizes with Olaparib 284
Rad51/Brca2 Disruptors Inhibit Homologous Recombination and Synergize with Olaparib in Pancreatic Cancer Cells 277
Targeting RNA degradation with small molecules: design and synthesis of selective RNA binders and development of ribonuclease targeting chimeras (RIBOTACs) 252
Investigating synthetic lethality and PARP inhibitor resistance in pancreatic cancer through enantiomer differential activity 252
Protein Tunnels: The Case of Urease Accessory Proteins 223
Differential enantiomers activity of ARN24089 to achieve synthetic lethality in pancreatic cancer 201
Synthetic Lethality Triggered by Combining Olaparib with BRCA2-Rad51 Disruptors 199
Design and synthesis of RAD51-BRCA2 protein-protein interaction disruptors to trigger synthetic lethality with Olaparib in pancreatic cancer cells 195
Synthesis of natural urolithin M6, a galloflavin mimetic, as a potential inhibitor of lactate dehydrogenase A 195
Collecting and assessing human lactate dehydrogenase-A conformations for structure-based virtual screening 190
Targeting the Protein Tunnels of the Urease Accessory Complex: A Theoretical Investigation 188
Searching for New Microbiome-Targeted Therapeutics through a Drug Repurposing Approach 188
Novel antiproliferative chimeric compounds with marked histone deacetylase inhibitory activity. 183
Innovative Strategy toward Mutant CFTR Rescue in Cystic Fibrosis: Design and Synthesis of Thiadiazole Inhibitors of the E3 Ligase RNF5 182
Proteostasis Regulators in Cystic Fibrosis: Current Development and Future Perspectives 171
Kernel-Based, Partial Least Squares Quantitative Structure-Retention Relationship Model for UPLC Retention Time Prediction: A Useful Tool for Metabolite Identification 170
Discovery of Multitarget Agents Active as Broad-Spectrum Antivirals and Correctors of Cystic Fibrosis Transmembrane Conductance Regulator for Associated Pulmonary Diseases 162
Pharmacological Inhibition of the Ubiquitin Ligase RNF5 Rescues F508del-CFTR in Cystic Fibrosis Airway Epithelia 162
Structure-based targeting of the lipid A-modifying enzyme PmrC to contrast colistin resistance in Acinetobacter baumannii 161
Exploration of the Neuromodulatory Properties of Fyn and GSK-3β Kinases Exploiting 7-Azaindole-Based Inhibitors 161
Discovery and SAR of 1,3,4-thiadiazole derivatives as potent Abl tyrosine kinase inhibitors and cytodifferentiating agents. 161
Development of a multisite model for Ni(II) ion in solution from thermodynamic and kinetic data 139
Identification of N-acylhydrazone derivatives as novel lactate dehydrogenase A inhibitors 139
IN SEARCH OF SMALL MOLECULES TARGETING RAD52 FOR SYNTHETIC LETHALITY 135
Protein Dynamics of the HIF-2α PAS-B Domain upon Heterodimerization and Ligand Binding 133
Chalcone-based carbamates for Alzheimer's disease treatment 131
TARGETING RAD52 FOR SYNTHETIC LETHALITY: DISCOVERY OF A NOVEL SMALL MOLECULE AS A PROMISING INHIBITOR FOR CANCER THERAPY 124
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Structure-based design of small-molecule protein–protein interaction modulators: the story so far 117
N-(thiazol-2-yl)-2-thiophene carboxamide derivatives as Abl inhibitors identified by a pharmacophore-based database screening of commercially available compounds 116
Targeting RAD51-BRCA2 Interaction to Enhance Synthetic Lethality with Olaparib in Pancreatic Cancer: Development of a Novel Phenyl Furan-Quinoline-Carboxylic Acid Series 115
Triggering RNA degradation with small molecules: development of RIBOnuclease TArgeting Chimeras (RIBOTACs) 115
Crassiflorone derivatives that inhibit Trypanosoma brucei glyceraldehyde-3-phosphate dehydrogenase (TbGAPDH) and Trypanosoma cruzi trypanothione reductase (TcTR) and display trypanocidal activity 109
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Divide et impera: An in silico screening targeting hcmv ppul44 processivity factor homodimerization identifies small molecules inhibiting viral replication 95
Target Identification with Live-Cell Photoaffinity Labeling and Mechanism of Action Elucidation of ARN23765, a Highly Potent CFTR Corrector 90
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NOVEL INHIBITORS OF PVHL-ELONGIN C BINDING 87
DESIGN AND SYNTHESIS OF SMALL MOLECULES TARGETING PRE-MIRNA21 TOWARD THE DEVELOPMENT OF RIBONUCLEASE TARGETING CHIMERAS (RIBOTACS) TO REGULATE THE ONCOGENIC MIRNA21 86
A combined targeted/phenotypic approach for the identification of new antiangiogenics agents active on a zebrafish model: From in silico screening to cyclodextrin formulation 84
Design and synthesis of BRCA2-RAD51 disruptors to induce synthetic lethality in anticancer therapy 83
Morphological inhibitors of aggregation-prone amyloid-β conformers: A computational exploration 81
COMPOUNDS WITH DDX3 INHIBITORY ACTIVITY AND USES THEREOF 74
Alkyl Tail Variation on Chalcone‐Based Quaternary Pyridinium Salts as Rule‐of‐Thumb for Antimicrobial Activity 65
NON PEPTIDIC 14-3-3 INHIBITORS AND THE USE THEREOF 64
Structure-based virtual screening allows the identification of efficient modulators of E-cadherin-mediated cell-cell adhesion 61
A chemical biology probe identified through 19F NMR screening stimulates RAD51 oligomerization and disrupts BRC4 binding 55
Discovery of the first small molecule inhibitor of human DDX3 specifically designed to target the RNA binding site: Towards the next generation HIV-1 inhibitors 48
Studies on the ATP Binding Site of Fyn Kinase for the Identification of New Inhibitors and Their Evaluation as Potential Agents against Tauopathies and Tumors 47
Fyn kinase in brain diseases and cancer: The search for inhibitors 46
3D QSAR models built on structure-based alignments of Abl tyrosine kinase inhibitors 43
Computational techniques are valuable tools for the discovery of protein-protein interaction inhibitors: the 14-3-3σ case 42
Identification of Hck Inhibitors As Hits for the Development of Antileukemia and Anti-HIV Agents 40
Determination of permeability and lipophilicity of pyrazolo-pyrimidine tyrosine kinase inhibitors and correlation with biological data 38
Inhibitors of human immunodeficiency virus-1 replication targeting the human DEAD-box polypeptide 3 (DDX3) RNA helicase 35
Targeting the human DEAD-box polypeptide 3 (DDX3) RNA helicase as a novel strategy to inhibit viral replication 34
N-[2-methyl-5-(triazol-1-yl)phenyl]pyrimidin-2-amine as a Scaffold for the synthesis of inhibitors of Bcr-Abl 33
Design and synthesis of thiadiazoles and thiazoles targeting the Bcr-Abl T315I mutant: From docking false positives to ATP-noncompetitive inhibitors 33
Toward the Discovery of Novel Anti-HIV Drugs. Second-Generation Inhibitors of the Cellular ATPase DDX3 with Improved Anti-HIV Activity: Synthesis, Structure-Activity Relationship Analysis, Cytotoxicity Studies, and Target Validation 28
Next generation of antiretroviral agents targeting the RNA binding site of the HIV-1 cellular cofactor DDX3: an innovative therapeutic approach 28
Pharmacophore modeling and molecular docking led to the discovery of inhibitors of human immunodeficiency virus-1 replication targeting the human cellular aspartic acid-glutamic acid-alanine-aspartic acid box polypeptide 3 25
Totale 9.087
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Categoria #
all - tutte 22.929
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 22.929
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022501 0 5 37 17 45 29 14 90 25 35 110 94
2022/2023768 59 130 52 84 85 40 36 52 111 42 31 46
2023/2024304 11 51 15 22 16 57 9 34 9 34 29 17
2024/20251.447 35 114 75 82 199 37 112 54 38 144 170 387
2025/20264.275 372 383 329 420 379 207 404 239 750 251 270 271
2026/2027326 183 143 0 0 0 0 0 0 0 0 0 0
Totale 9.087