CRIS Current Research Information System

FALCHI, FEDERICO
 Distribuzione geografica
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Continente #
AS - Asia 2.908
NA - Nord America 2.578
EU - Europa 2.048
SA - Sud America 241
AF - Africa 175
OC - Oceania 38
Continente sconosciuto - Info sul continente non disponibili 1
Totale 7.989
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Nazione #
US - Stati Uniti d'America 2.529
IT - Italia 824
SG - Singapore 791
CN - Cina 749
VN - Vietnam 569
GB - Regno Unito 267
HK - Hong Kong 260
BR - Brasile 188
DE - Germania 181
SE - Svezia 180
IN - India 135
KR - Corea 121
FR - Francia 119
JP - Giappone 84
NL - Olanda 73
RU - Federazione Russa 69
IE - Irlanda 59
CI - Costa d'Avorio 46
ZA - Sudafrica 44
BG - Bulgaria 38
TG - Togo 35
AU - Australia 34
UA - Ucraina 31
FI - Finlandia 30
ES - Italia 25
CA - Canada 24
PL - Polonia 24
NG - Nigeria 23
CH - Svizzera 22
PK - Pakistan 22
AR - Argentina 21
AT - Austria 21
EE - Estonia 21
IQ - Iraq 21
MX - Messico 20
BD - Bangladesh 18
JO - Giordania 18
TW - Taiwan 18
DK - Danimarca 16
PH - Filippine 16
TR - Turchia 16
ID - Indonesia 12
MY - Malesia 10
TH - Thailandia 10
BE - Belgio 8
GR - Grecia 8
HR - Croazia 8
VE - Venezuela 7
IR - Iran 6
MA - Marocco 6
CO - Colombia 5
EC - Ecuador 5
LT - Lituania 5
NP - Nepal 5
UZ - Uzbekistan 5
AE - Emirati Arabi Uniti 4
BO - Bolivia 4
BY - Bielorussia 4
CZ - Repubblica Ceca 4
EG - Egitto 4
ET - Etiopia 4
IL - Israele 4
PY - Paraguay 4
SA - Arabia Saudita 4
SC - Seychelles 4
LV - Lettonia 3
NZ - Nuova Zelanda 3
SN - Senegal 3
UY - Uruguay 3
CL - Cile 2
DZ - Algeria 2
JM - Giamaica 2
KZ - Kazakistan 2
LB - Libano 2
MU - Mauritius 2
PE - Perù 2
RO - Romania 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AL - Albania 1
BA - Bosnia-Erzegovina 1
BZ - Belize 1
CG - Congo 1
GT - Guatemala 1
HN - Honduras 1
HU - Ungheria 1
KE - Kenya 1
KG - Kirghizistan 1
LA - Repubblica Popolare Democratica del Laos 1
LK - Sri Lanka 1
MD - Moldavia 1
MM - Myanmar 1
NC - Nuova Caledonia 1
OM - Oman 1
PS - Palestinian Territory 1
PT - Portogallo 1
SM - San Marino 1
Totale 7.989
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Città #
Singapore 538
Ashburn 316
Bologna 254
Hong Kong 233
Fairfield 199
Southend 199
Hefei 193
Chandler 180
San Jose 146
Santa Clara 139
Ho Chi Minh City 133
Hanoi 122
Seattle 113
Woodbridge 110
Seoul 96
Houston 93
Wilmington 83
Beijing 77
Cambridge 72
Ann Arbor 65
Milan 61
Tokyo 61
Dublin 60
Boardman 52
Los Angeles 51
Abidjan 46
Princeton 45
Lauterbourg 44
New York 39
Buffalo 36
Lomé 35
Sofia 35
Dong Ket 34
Florence 31
Verona 31
Council Bluffs 30
Berlin 29
Sydney 27
São Paulo 27
Redmond 26
Da Nang 25
Nanjing 24
Johannesburg 22
Dallas 21
Frankfurt am Main 21
Abeokuta 20
Guangzhou 20
Haiphong 20
Rome 20
Westminster 20
Calcinelli 19
Bengaluru 18
Genoa 18
Helsinki 17
Padova 17
Redondo Beach 17
Amman 16
Chicago 16
Munich 16
Amsterdam 15
Mumbai 15
Shanghai 14
Warsaw 14
Jacksonville 13
San Diego 13
Vienna 13
Chennai 12
London 12
Modena 12
Saint Petersburg 12
Baghdad 11
Copenhagen 11
Nanchang 11
Nuremberg 11
Shenyang 11
Atlanta 10
Hangzhou 10
Jhelum 10
Jinan 10
Naples 10
Zurich 10
Belo Horizonte 9
Montreal 9
Stockholm 9
Boston 8
Brooklyn 8
Brussels 8
Claymont 8
Falkenstein 8
Lappeenranta 8
San Francisco 8
Tianjin 8
Toronto 8
Bern 7
Denver 7
Falls Church 7
Jiaxing 7
Orem 7
Pesaro 7
Quartu Sant'Elena 7
Totale 4.936
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Nome #
Probing allosteric communication with combined molecular dynamics simulations and network analysis 400
Design and synthesis of small molecules targeting pre-miRNA21 toward the development of ribonuclease targeting chimeras (RIBOTACs) to regulate the oncogenic miRNA21 317
2-Phenoxy-1,4-naphthoquinones: From a Multitarget Antitrypanosomal to a Potential Antitumor Profile 309
Multitarget Strategy to Address Alzheimer's Disease: Design, Synthesis, Biological Evaluation, and Computational Studies of Coumarin-Based Derivatives 287
Rad51/Brca2 Disruptors Inhibit Homologous Recombination and Synergize with Olaparib in Pancreatic Cancer Cells 275
Synthetic Lethality in Pancreatic Cancer: Discovery of a New RAD51-BRCA2 Small Molecule Disruptor That Inhibits Homologous Recombination and Synergizes with Olaparib 270
Investigating synthetic lethality and PARP inhibitor resistance in pancreatic cancer through enantiomer differential activity 224
Protein Tunnels: The Case of Urease Accessory Proteins 218
Synthetic Lethality Triggered by Combining Olaparib with BRCA2-Rad51 Disruptors 193
Differential enantiomers activity of ARN24089 to achieve synthetic lethality in pancreatic cancer 187
Synthesis of natural urolithin M6, a galloflavin mimetic, as a potential inhibitor of lactate dehydrogenase A 187
Collecting and assessing human lactate dehydrogenase-A conformations for structure-based virtual screening 186
Targeting RNA degradation with small molecules: design and synthesis of selective RNA binders and development of ribonuclease targeting chimeras (RIBOTACs) 183
Targeting the Protein Tunnels of the Urease Accessory Complex: A Theoretical Investigation 181
Design and synthesis of RAD51-BRCA2 protein-protein interaction disruptors to trigger synthetic lethality with Olaparib in pancreatic cancer cells 178
Novel antiproliferative chimeric compounds with marked histone deacetylase inhibitory activity. 176
Searching for New Microbiome-Targeted Therapeutics through a Drug Repurposing Approach 176
Proteostasis Regulators in Cystic Fibrosis: Current Development and Future Perspectives 163
Innovative Strategy toward Mutant CFTR Rescue in Cystic Fibrosis: Design and Synthesis of Thiadiazole Inhibitors of the E3 Ligase RNF5 160
Pharmacological Inhibition of the Ubiquitin Ligase RNF5 Rescues F508del-CFTR in Cystic Fibrosis Airway Epithelia 159
Discovery of Multitarget Agents Active as Broad-Spectrum Antivirals and Correctors of Cystic Fibrosis Transmembrane Conductance Regulator for Associated Pulmonary Diseases 156
Kernel-Based, Partial Least Squares Quantitative Structure-Retention Relationship Model for UPLC Retention Time Prediction: A Useful Tool for Metabolite Identification 155
Discovery and SAR of 1,3,4-thiadiazole derivatives as potent Abl tyrosine kinase inhibitors and cytodifferentiating agents. 150
Identification of N-acylhydrazone derivatives as novel lactate dehydrogenase A inhibitors 133
Structure-based targeting of the lipid A-modifying enzyme PmrC to contrast colistin resistance in Acinetobacter baumannii 131
Development of a multisite model for Ni(II) ion in solution from thermodynamic and kinetic data 129
Protein Dynamics of the HIF-2α PAS-B Domain upon Heterodimerization and Ligand Binding 128
Chalcone-based carbamates for Alzheimer's disease treatment 125
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Structure-based design of small-molecule protein–protein interaction modulators: the story so far 116
N-(thiazol-2-yl)-2-thiophene carboxamide derivatives as Abl inhibitors identified by a pharmacophore-based database screening of commercially available compounds 110
TARGETING RAD52 FOR SYNTHETIC LETHALITY: DISCOVERY OF A NOVEL SMALL MOLECULE AS A PROMISING INHIBITOR FOR CANCER THERAPY 105
IN SEARCH OF SMALL MOLECULES TARGETING RAD52 FOR SYNTHETIC LETHALITY 103
Triggering RNA degradation with small molecules: development of RIBOnuclease TArgeting Chimeras (RIBOTACs) 103
Crassiflorone derivatives that inhibit Trypanosoma brucei glyceraldehyde-3-phosphate dehydrogenase (TbGAPDH) and Trypanosoma cruzi trypanothione reductase (TcTR) and display trypanocidal activity 103
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Divide et impera: An in silico screening targeting hcmv ppul44 processivity factor homodimerization identifies small molecules inhibiting viral replication 90
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Exploration of the Neuromodulatory Properties of Fyn and GSK-3β Kinases Exploiting 7-Azaindole-Based Inhibitors 87
A combined targeted/phenotypic approach for the identification of new antiangiogenics agents active on a zebrafish model: From in silico screening to cyclodextrin formulation 83
Target Identification with Live-Cell Photoaffinity Labeling and Mechanism of Action Elucidation of ARN23765, a Highly Potent CFTR Corrector 81
DESIGN AND SYNTHESIS OF SMALL MOLECULES TARGETING PRE-MIRNA21 TOWARD THE DEVELOPMENT OF RIBONUCLEASE TARGETING CHIMERAS (RIBOTACS) TO REGULATE THE ONCOGENIC MIRNA21 73
NOVEL INHIBITORS OF PVHL-ELONGIN C BINDING 72
COMPOUNDS WITH DDX3 INHIBITORY ACTIVITY AND USES THEREOF 68
Targeting RAD51-BRCA2 Interaction to Enhance Synthetic Lethality with Olaparib in Pancreatic Cancer: Development of a Novel Phenyl Furan-Quinoline-Carboxylic Acid Series 60
NON PEPTIDIC 14-3-3 INHIBITORS AND THE USE THEREOF 58
Structure-based virtual screening allows the identification of efficient modulators of E-cadherin-mediated cell-cell adhesion 57
Design and synthesis of BRCA2-RAD51 disruptors to induce synthetic lethality in anticancer therapy 54
Discovery of the first small molecule inhibitor of human DDX3 specifically designed to target the RNA binding site: Towards the next generation HIV-1 inhibitors 45
Studies on the ATP Binding Site of Fyn Kinase for the Identification of New Inhibitors and Their Evaluation as Potential Agents against Tauopathies and Tumors 43
Fyn kinase in brain diseases and cancer: The search for inhibitors 40
3D QSAR models built on structure-based alignments of Abl tyrosine kinase inhibitors 40
Computational techniques are valuable tools for the discovery of protein-protein interaction inhibitors: the 14-3-3σ case 38
Identification of Hck Inhibitors As Hits for the Development of Antileukemia and Anti-HIV Agents 38
Morphological inhibitors of aggregation-prone amyloid-β conformers: A computational exploration 37
Determination of permeability and lipophilicity of pyrazolo-pyrimidine tyrosine kinase inhibitors and correlation with biological data 36
Alkyl Tail Variation on Chalcone‐Based Quaternary Pyridinium Salts as Rule‐of‐Thumb for Antimicrobial Activity 34
Inhibitors of human immunodeficiency virus-1 replication targeting the human DEAD-box polypeptide 3 (DDX3) RNA helicase 33
Targeting the human DEAD-box polypeptide 3 (DDX3) RNA helicase as a novel strategy to inhibit viral replication 31
N-[2-methyl-5-(triazol-1-yl)phenyl]pyrimidin-2-amine as a Scaffold for the synthesis of inhibitors of Bcr-Abl 30
Design and synthesis of thiadiazoles and thiazoles targeting the Bcr-Abl T315I mutant: From docking false positives to ATP-noncompetitive inhibitors 28
Next generation of antiretroviral agents targeting the RNA binding site of the HIV-1 cellular cofactor DDX3: an innovative therapeutic approach 27
Toward the Discovery of Novel Anti-HIV Drugs. Second-Generation Inhibitors of the Cellular ATPase DDX3 with Improved Anti-HIV Activity: Synthesis, Structure-Activity Relationship Analysis, Cytotoxicity Studies, and Target Validation 26
Pharmacophore modeling and molecular docking led to the discovery of inhibitors of human immunodeficiency virus-1 replication targeting the human cellular aspartic acid-glutamic acid-alanine-aspartic acid box polypeptide 3 23
Totale 8.155
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Categoria #
all - tutte 19.679
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 19.679
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021120 0 0 0 0 0 0 0 0 0 24 14 82
2021/2022548 47 5 37 17 45 29 14 90 25 35 110 94
2022/2023768 59 130 52 84 85 40 36 52 111 42 31 46
2023/2024304 11 51 15 22 16 57 9 34 9 34 29 17
2024/20251.447 35 114 75 82 199 37 112 54 38 144 170 387
2025/20263.669 372 383 329 420 379 207 404 239 750 186 0 0
Totale 8.155