The present invention relates to novel inhibitors of pVHL-Elongin C binding, methods for identifying such inhibitors as well as compounds comprising a first moiety binding to an Elongin B, Elongin C, Cul2 and/or Rbx1 complex, a linker and a second moiety for HIF-2α.
NOVEL INHIBITORS OF PVHL-ELONGIN C BINDING / IACOBELLI Stefano, TINARI Nicola, FALCHI Federico, RECANATINI Maurizio, FICHERA Imma, PICCOLO Enza,. - (2014).
NOVEL INHIBITORS OF PVHL-ELONGIN C BINDING
FALCHI Federico;RECANATINI Maurizio;
2014
Abstract
The present invention relates to novel inhibitors of pVHL-Elongin C binding, methods for identifying such inhibitors as well as compounds comprising a first moiety binding to an Elongin B, Elongin C, Cul2 and/or Rbx1 complex, a linker and a second moiety for HIF-2α.File in questo prodotto:
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