FALCHI, FEDERICO
FALCHI, FEDERICO
DIPARTIMENTO DI FARMACIA E BIOTECNOLOGIE
Ricercatori a tempo determinato
2-Phenoxy-1,4-naphthoquinones: From a Multitarget Antitrypanosomal to a Potential Antitumor Profile
2015 Prati, Federica; Bergamini, Christian; Molina, Maria Teresa; Falchi, Federico; Cavalli, Andrea; Kaiser, Marcel; Brun, Reto; Fato, Romana; Bolognesi, Maria Laura
3D QSAR models built on structure-based alignments of Abl tyrosine kinase inhibitors
2009 Falchi F.; Manetti F.; Carraro F.; Naldini A.; Maga G.; Crespan E.; Schenone S.; Bruno O.; Brullo C.; Botta M.
A combined targeted/phenotypic approach for the identification of new antiangiogenics agents active on a zebrafish model: From in silico screening to cyclodextrin formulation
2012 Radi M.; Evensen L.; Dreassi E.; Zamperini C.; Caporicci M.; Falchi F.; Musumeci F.; Schenone S.; Lorens J.B.; Botta M.
Chalcone-based carbamates for Alzheimer's disease treatment
2017 Rampa, Angela; Montanari, Serena; Pruccoli, Letizia; Bartolini, Manuela; Falchi, Federico; Feoli, Alessandra; Cavalli, Andrea; Belluti, Federica; Gobbi, Silvia; Tarozzi, Andrea; Bisi, Alessandra
Collecting and assessing human lactate dehydrogenase-A conformations for structure-based virtual screening
2013 R. Buonfiglio; M. Ferraro; F. Falchi; A. Cavalli; M. Masetti; M. Recanatini
COMPOUNDS WITH DDX3 INHIBITORY ACTIVITY AND USES THEREOF
2011 RADI MARCO; BOTTA MAURIZIO; FALCHI FEDERICO; MAGA GIOVANNI; BALDANTI FAUSTO; PAOLUCCI STEFANIA
Computational techniques are valuable tools for the discovery of protein-protein interaction inhibitors: the 14-3-3σ case
2011 Corradi V; Mancini M; Santucci MA; Carlomagno T; Sanfelice D; Mori M; Vignaroli G; Falchi F; Manetti F; Radi M; Botta M
Crassiflorone derivatives that inhibit Trypanosoma brucei glyceraldehyde-3-phosphate dehydrogenase (TbGAPDH) and Trypanosoma cruzi trypanothione reductase (TcTR) and display trypanocidal activity
2017 Uliassi, Elisa; Fiorani, Giulia; Krauth-Siegel, R. Luise; Bergamini, Christian; Fato, Romana; Bianchini, Giulia; Carlos Menéndez, J.; Molina, Maria Teresa; López-Montero, Eulogio; Falchi, Federico; Cavalli, Andrea; Gul, Sheraz; Kuzikov, Maria; Ellinger, Bernhard; Witt, Gesa; Moraes, Carolina B.; Freitas-Junior, Lucio H.; Borsari, Chiara; Costi, Maria Paola; Bolognesi, Maria Laura*
Design and synthesis of thiadiazoles and thiazoles targeting the Bcr-Abl T315I mutant: From docking false positives to ATP-noncompetitive inhibitors
2010 Radi M.; Crespan E.; Falchi F.; Bernardo V.; Zanoli S.; Manetti F.; Schenone S.; Maga G.; Botta M.
Determination of permeability and lipophilicity of pyrazolo-pyrimidine tyrosine kinase inhibitors and correlation with biological data
2009 Dreassi E.; Zizzari A.T.; Falchi F.; Schenone S.; Santucci A.; Maga G.; Botta M.
Development of a multisite model for Ni(II) ion in solution from thermodynamic and kinetic data
2017 Masetti, Matteo; Musiani, Francesco; Bernetti, Mattia; Falchi, Federico; Cavalli, Andrea; Ciurli, Stefano; Recanatini, Maurizio
Discovery and SAR of 1,3,4-thiadiazole derivatives as potent Abl tyrosine kinase inhibitors and cytodifferentiating agents.
2008 Radi M; Crespan E; Botta G; Falchi F; Maga G; Manetti F; Corradi V; Mancini M; Santucci MA; Schenone S; Botta M.
Discovery of Multitarget Agents Active as Broad-Spectrum Antivirals and Correctors of Cystic Fibrosis Transmembrane Conductance Regulator for Associated Pulmonary Diseases
2017 Tassini, Sabrina; Sun, Liang; Lanko, Kristina; Crespan, Emmanuele; Langron, Emily; Falchi, Federico; Kissova, Miroslava; Armijos-Rivera, Jorge I.; Delang, Leen; Mirabelli, Carmen; Neyts, Johan; Pieroni, Marco; Cavalli, Andrea; Costantino, Gabriele; Maga, Giovanni; Vergani, Paola; Leyssen, Pieter; Radi, Marco
Discovery of the first small molecule inhibitor of human DDX3 specifically designed to target the RNA binding site: Towards the next generation HIV-1 inhibitors
2012 Radi M.; Falchi F.; Garbelli A.; Samuele A.; Bernardo V.; Paolucci S.; Baldanti F.; Schenone S.; Manetti F.; Maga G.; Botta M.
Divide et impera: An in silico screening targeting hcmv ppul44 processivity factor homodimerization identifies small molecules inhibiting viral replication
2021 Ghassabian H.; Falchi F.; Timmoneri M.; Mercorelli B.; Loregian A.; Palu G.; Alvisi G.
Fyn kinase in brain diseases and cancer: The search for inhibitors
2011 Schenone S.; Brullo C.; Musumeci F.; Biava M.; Falchi F.; Botta M.
Identification of Hck Inhibitors As Hits for the Development of Antileukemia and Anti-HIV Agents
2013 Tintori C.; Laurenzana I.; LaRocca F.; Falchi F.; Carraro F.; Ruiz A.; Este J.A.; Kissova M.; Crespan E.; Maga G.; Biava M.; Brullo C.; Schenone S.; Botta M.
Identification of N-acylhydrazone derivatives as novel lactate dehydrogenase A inhibitors
2015 Sebastiano Rupiani; Rosa Buonfiglio; Marcella Manerba; Lorenza Di Ianni; Marina Vettraino; Elisa Giacomini; Matteo Masetti; Federico Falchi; Giuseppina Di Stefano; Marinella Roberti; Maurizio Recanatini
Inhibitors of human immunodeficiency virus-1 replication targeting the human DEAD-box polypeptide 3 (DDX3) RNA helicase
2010 Giovanni Maga, Federico Falchi, Anna Garbelli, Marco Radi, Stefania Paolucci, Fausto Baldanti, Maurizio Botta
Innovative Strategy toward Mutant CFTR Rescue in Cystic Fibrosis: Design and Synthesis of Thiadiazole Inhibitors of the E3 Ligase RNF5
2023 Brusa, Irene; Sondo, Elvira; Pesce, Emanuela; Tomati, Valeria; Gioia, Dario; Falchi, Federico; Balboni, Beatrice; Ortega Martínez, Jose Antonio; Veronesi, Marina; Romeo, Elisa; Margaroli, Natasha; Recanatini, Maurizio; Girotto, Stefania; Pedemonte, Nicoletta; Roberti, Marinella; Cavalli, Andrea
| Titolo | Autore(i) | Anno | Periodico | Editore | Tipo | File |
|---|---|---|---|---|---|---|
| 2-Phenoxy-1,4-naphthoquinones: From a Multitarget Antitrypanosomal to a Potential Antitumor Profile | Prati, Federica; Bergamini, Christian; Molina, Maria Teresa; Falchi, Federico; Cavalli, Andrea; K...aiser, Marcel; Brun, Reto; Fato, Romana; Bolognesi, Maria Laura | 2015-01-01 | JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
| 3D QSAR models built on structure-based alignments of Abl tyrosine kinase inhibitors | Falchi F.; Manetti F.; Carraro F.; Naldini A.; Maga G.; Crespan E.; Schenone S.; Bruno O.; Brullo... C.; Botta M. | 2009-01-01 | CHEMMEDCHEM | - | 1.01 Articolo in rivista | - |
| A combined targeted/phenotypic approach for the identification of new antiangiogenics agents active on a zebrafish model: From in silico screening to cyclodextrin formulation | Radi M.; Evensen L.; Dreassi E.; Zamperini C.; Caporicci M.; Falchi F.; Musumeci F.; Schenone S.;... Lorens J.B.; Botta M. | 2012-01-01 | BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | - | 1.01 Articolo in rivista | - |
| Chalcone-based carbamates for Alzheimer's disease treatment | Rampa, Angela; Montanari, Serena; Pruccoli, Letizia; Bartolini, Manuela; Falchi, Federico; Feoli,... Alessandra; Cavalli, Andrea; Belluti, Federica; Gobbi, Silvia; Tarozzi, Andrea; Bisi, Alessandra | 2017-01-01 | FUTURE MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
| Collecting and assessing human lactate dehydrogenase-A conformations for structure-based virtual screening | R. Buonfiglio; M. Ferraro; F. Falchi; A. Cavalli; M. Masetti; M. Recanatini | 2013-01-01 | JOURNAL OF CHEMICAL INFORMATION AND MODELING | - | 1.01 Articolo in rivista | - |
| COMPOUNDS WITH DDX3 INHIBITORY ACTIVITY AND USES THEREOF | RADI MARCO; BOTTA MAURIZIO; FALCHI FEDERICO; MAGA GIOVANNI; BALDANTI FAUSTO; PAOLUCCI STEFANIA | 2011-01-01 | - | - | 6.01 Brevetto | - |
| Computational techniques are valuable tools for the discovery of protein-protein interaction inhibitors: the 14-3-3σ case | Corradi V; Mancini M; Santucci MA; Carlomagno T; Sanfelice D; Mori M; Vignaroli G; Falchi F; Mane...tti F; Radi M; Botta M | 2011-01-01 | BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS | - | 1.01 Articolo in rivista | - |
| Crassiflorone derivatives that inhibit Trypanosoma brucei glyceraldehyde-3-phosphate dehydrogenase (TbGAPDH) and Trypanosoma cruzi trypanothione reductase (TcTR) and display trypanocidal activity | Uliassi, Elisa; Fiorani, Giulia; Krauth-Siegel, R. Luise; Bergamini, Christian; Fato, Romana; Bia...nchini, Giulia; Carlos Menéndez, J.; Molina, Maria Teresa; López-Montero, Eulogio; Falchi, Federico; Cavalli, Andrea; Gul, Sheraz; Kuzikov, Maria; Ellinger, Bernhard; Witt, Gesa; Moraes, Carolina B.; Freitas-Junior, Lucio H.; Borsari, Chiara; Costi, Maria Paola; Bolognesi, Maria Laura* | 2017-01-01 | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
| Design and synthesis of thiadiazoles and thiazoles targeting the Bcr-Abl T315I mutant: From docking false positives to ATP-noncompetitive inhibitors | Radi M.; Crespan E.; Falchi F.; Bernardo V.; Zanoli S.; Manetti F.; Schenone S.; Maga G.; Botta M. | 2010-01-01 | CHEMMEDCHEM | - | 1.01 Articolo in rivista | - |
| Determination of permeability and lipophilicity of pyrazolo-pyrimidine tyrosine kinase inhibitors and correlation with biological data | Dreassi E.; Zizzari A.T.; Falchi F.; Schenone S.; Santucci A.; Maga G.; Botta M. | 2009-01-01 | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
| Development of a multisite model for Ni(II) ion in solution from thermodynamic and kinetic data | Masetti, Matteo; Musiani, Francesco; Bernetti, Mattia; Falchi, Federico; Cavalli, Andrea; Ciurli,... Stefano; Recanatini, Maurizio | 2017-01-01 | JOURNAL OF COMPUTATIONAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
| Discovery and SAR of 1,3,4-thiadiazole derivatives as potent Abl tyrosine kinase inhibitors and cytodifferentiating agents. | Radi M; Crespan E; Botta G; Falchi F; Maga G; Manetti F; Corradi V; Mancini M; Santucci MA; Schen...one S; Botta M. | 2008-01-01 | BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | - | 1.01 Articolo in rivista | - |
| Discovery of Multitarget Agents Active as Broad-Spectrum Antivirals and Correctors of Cystic Fibrosis Transmembrane Conductance Regulator for Associated Pulmonary Diseases | Tassini, Sabrina; Sun, Liang; Lanko, Kristina; Crespan, Emmanuele; Langron, Emily; Falchi, Federi...co; Kissova, Miroslava; Armijos-Rivera, Jorge I.; Delang, Leen; Mirabelli, Carmen; Neyts, Johan; Pieroni, Marco; Cavalli, Andrea; Costantino, Gabriele; Maga, Giovanni; Vergani, Paola; Leyssen, Pieter; Radi, Marco | 2017-01-01 | JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
| Discovery of the first small molecule inhibitor of human DDX3 specifically designed to target the RNA binding site: Towards the next generation HIV-1 inhibitors | Radi M.; Falchi F.; Garbelli A.; Samuele A.; Bernardo V.; Paolucci S.; Baldanti F.; Schenone S.; ...Manetti F.; Maga G.; Botta M. | 2012-01-01 | BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | - | 1.01 Articolo in rivista | - |
| Divide et impera: An in silico screening targeting hcmv ppul44 processivity factor homodimerization identifies small molecules inhibiting viral replication | Ghassabian H.; Falchi F.; Timmoneri M.; Mercorelli B.; Loregian A.; Palu G.; Alvisi G. | 2021-01-01 | VIRUSES | - | 1.01 Articolo in rivista | Divide et impera_ An In Silico Screening Targeting HCMV ppUL44 Processivity Factor Homodimerization Identifies Small Molecules Inhibiting Viral Replication.pdf |
| Fyn kinase in brain diseases and cancer: The search for inhibitors | Schenone S.; Brullo C.; Musumeci F.; Biava M.; Falchi F.; Botta M. | 2011-01-01 | CURRENT MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
| Identification of Hck Inhibitors As Hits for the Development of Antileukemia and Anti-HIV Agents | Tintori C.; Laurenzana I.; LaRocca F.; Falchi F.; Carraro F.; Ruiz A.; Este J.A.; Kissova M.; Cre...span E.; Maga G.; Biava M.; Brullo C.; Schenone S.; Botta M. | 2013-01-01 | CHEMMEDCHEM | - | 1.01 Articolo in rivista | - |
| Identification of N-acylhydrazone derivatives as novel lactate dehydrogenase A inhibitors | Sebastiano Rupiani; Rosa Buonfiglio; Marcella Manerba; Lorenza Di Ianni; Marina Vettraino; Elisa ...Giacomini; Matteo Masetti; Federico Falchi; Giuseppina Di Stefano; Marinella Roberti; Maurizio Recanatini | 2015-01-01 | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
| Inhibitors of human immunodeficiency virus-1 replication targeting the human DEAD-box polypeptide 3 (DDX3) RNA helicase | Giovanni Maga, Federico Falchi, Anna Garbelli, Marco Radi, Stefania Paolucci, Fausto Baldanti, Ma...urizio Botta | 2010-01-01 | RETROVIROLOGY | - | 1.01 Articolo in rivista | - |
| Innovative Strategy toward Mutant CFTR Rescue in Cystic Fibrosis: Design and Synthesis of Thiadiazole Inhibitors of the E3 Ligase RNF5 | Brusa, Irene; Sondo, Elvira; Pesce, Emanuela; Tomati, Valeria; Gioia, Dario; Falchi, Federico; Ba...lboni, Beatrice; Ortega Martínez, Jose Antonio; Veronesi, Marina; Romeo, Elisa; Margaroli, Natasha; Recanatini, Maurizio; Girotto, Stefania; Pedemonte, Nicoletta; Roberti, Marinella; Cavalli, Andrea | 2023-01-01 | JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | brusa-et-al-2023-innovative-strategy-toward-mutant-cftr-rescue-in-cystic-fibrosis-design-and-synthesis-of-thiadiazole.pdf |