CRIS Current Research Information System

TUMIATTI, VINCENZO
 Distribuzione geografica
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Continente #
NA - Nord America 4.744
EU - Europa 4.285
AS - Asia 1.539
AF - Africa 273
SA - Sud America 26
OC - Oceania 6
Continente sconosciuto - Info sul continente non disponibili 2
Totale 10.875
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Nazione #
US - Stati Uniti d'America 4.734
IT - Italia 1.515
GB - Regno Unito 934
CN - Cina 691
SG - Singapore 436
DE - Germania 412
SE - Svezia 405
UA - Ucraina 290
IN - India 195
FR - Francia 163
IE - Irlanda 133
RU - Federazione Russa 121
TG - Togo 106
VN - Vietnam 90
EE - Estonia 72
ZA - Sudafrica 65
CI - Costa d'Avorio 64
BG - Bulgaria 45
JO - Giordania 31
BE - Belgio 24
ES - Italia 23
HR - Croazia 23
SC - Seychelles 23
CH - Svizzera 18
NL - Olanda 18
FI - Finlandia 17
PL - Polonia 17
ID - Indonesia 15
JP - Giappone 15
TR - Turchia 14
BR - Brasile 12
GR - Grecia 11
KR - Corea 11
IR - Iran 10
CA - Canada 9
CZ - Repubblica Ceca 9
NG - Nigeria 8
AT - Austria 6
LB - Libano 6
CL - Cile 5
DK - Danimarca 5
RO - Romania 5
AU - Australia 4
MT - Malta 4
MY - Malesia 4
PT - Portogallo 4
TW - Taiwan 4
CO - Colombia 3
PK - Pakistan 3
SK - Slovacchia (Repubblica Slovacca) 3
TH - Thailandia 3
BO - Bolivia 2
DZ - Algeria 2
EC - Ecuador 2
EU - Europa 2
HK - Hong Kong 2
HU - Ungheria 2
LK - Sri Lanka 2
MA - Marocco 2
NZ - Nuova Zelanda 2
SM - San Marino 2
AE - Emirati Arabi Uniti 1
AL - Albania 1
AZ - Azerbaigian 1
BD - Bangladesh 1
CR - Costa Rica 1
EG - Egitto 1
FK - Isole Falkland (Malvinas) 1
IL - Israele 1
IQ - Iraq 1
LU - Lussemburgo 1
MD - Moldavia 1
MU - Mauritius 1
NO - Norvegia 1
PE - Perù 1
PH - Filippine 1
SA - Arabia Saudita 1
TN - Tunisia 1
Totale 10.875
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Città #
Southend 849
Fairfield 533
Singapore 383
Chandler 378
Ashburn 373
Santa Clara 348
Houston 264
Woodbridge 243
Wilmington 236
Seattle 223
Bologna 213
Princeton 203
Ann Arbor 199
Jacksonville 196
Cambridge 178
Boardman 137
Dublin 133
Lomé 106
Padova 96
Nanjing 87
Westminster 87
Abidjan 64
Milan 58
Berlin 56
New York 54
Jinan 53
Dong Ket 52
Rome 51
Saint Petersburg 45
Shenyang 44
Sofia 44
Medford 42
Redmond 41
Beijing 36
Hebei 36
Turin 34
Mülheim 33
Amman 31
Cesena 31
San Diego 30
Nanchang 29
Los Angeles 28
Changsha 27
Tianjin 27
Guangzhou 26
Redwood City 24
Falls Church 23
Mahé 22
Brussels 21
Palermo 21
Rimini 21
Shanghai 21
Haikou 20
San Giorgio di Piano 20
Forlì 19
Hangzhou 19
Des Moines 18
Bremen 17
Taiyuan 16
Zhengzhou 16
Helsinki 15
Jiaxing 15
Norwalk 14
Ravenna 13
Benevento 12
Dearborn 12
Genoa 11
Jakarta 11
Modena 11
Naples 11
Florence 10
Ningbo 10
Olalla 10
Parma 10
Ancona 9
Bern 9
Chicago 9
Dallas 9
Hyderabad 9
Shenzhen 9
Taizhou 9
Abeokuta 8
Chiampo 8
Cormano 8
Fuzhou 8
Paris 8
Verona 8
Wuhan 8
Barcelona 7
Bari 7
Lanzhou 7
Livorno 7
Mohali 7
Pisa 7
Shijiazhuang 7
São Paulo 7
Tokyo 7
Warsaw 7
Amsterdam 6
Bühl 6
Totale 7.101
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Nome #
Trasportatori di membrana dei farmaci 662
Discovery of the First-in-Class GSK-3β/HDAC Dual Inhibitor as Disease-Modifying Agent To Combat Alzheimer's Disease. 249
Progettazione e sintesi di analoghi rigidi di metoctramina nello studio dei recettori muscarinici 195
Cytotoxicity of methoctramine and methoctramine-related polyamines. 178
Targeting topoisomerase II with trypthantrin derivatives: Discovery of 7-((2-(dimethylamino)ethyl)amino)indolo[2,1-b]quinazoline-6,12-dione as an antiproliferative agent and to treat cancer 176
Bis(7)-tacrine Derivatives as Multitarget-Directed Ligands: Focus on Anticholinesterase and Antiamyloid Activities 160
Structure-activity relationships of acetylcholinesterase noncovalent inhibitors based on a polyamine backbone. 3. Effect of replacing the inner polymethylene chain with cyclic moieties 158
Progettazione e sintesi di poliammine a potenziale attività antitumorale 154
DESIGN, SYNTHESIS AND BIOLOGICAL EVALUATION OF SUSTITUTED NAPHTHALENE IMIDES AND DIIMIDES AS ANTICANCER AGENT 152
Progettazione e sintesi di derivati poliamminici per il trattamento della malattia di Alzheimer 145
Structure-activity relationships of novel substituted naphthalene diimides as anticancer agents 141
null 141
Glycogen Synthase Kinase 3β: A New Gold Rush in Anti-Alzheimer’s Disease Multitarget Drug Discovery? 137
Cystamine-tacrine dimer: A new multi-target-directed ligand as potential therapeutic agent for Alzheimer's disease treatment. 136
null 135
Design, synthesis, and biological evaluation of prazosin-related derivatives as multipotent compounds 129
Design, synthesis, and biological evaluation of pirenzepine analogs bearing a 1,2-cyclohexanediamine and a perhydroquinoxaline units in exchange for the piperazine ring as antimuscarinics 123
Macrocyclic naphthalene diimides as G-quadruplex binders 123
Natural polyamines and synthetic analogs modify the growth and the morphology of Pyrus communis pollen tubes affecting ROS levels and causing cell death 123
Novel bis(7)-tacrine derivatives as multitarget ligands: focus on anti-cholinesterase and anti-amyloid activities 120
Study of the cytotoxic effects of the new synthetic isothiocyanate CM9 and its fullerene derivative on human T-leukemia cells 117
Synthetic polyamines activating autophagy: Effects on cancer cell death 115
Novel Class of Quinone-Bearing Polyamines as Multi-Target-Directed Ligands To Combat Alzheimer's Disease 115
Exploiting RNA as a new biomolecular target for synthetic polyamines 114
Exploring the effects of isothiocyanates on chemotherapeutic drugs 114
Multitarget-directed ligands: Innovative chemical probes and therapeutic tools against Alzheimer's disease 114
Heterocyclic inhibitors of AChE acylation and peripheral sites. 112
Multi-target-Directed Ligands To Combat Neurodegenerative Diseases 111
Preparation, characterization and in vitro evaluation of sterically stabilized liposome containing a naphthalenediimide derivative as anticancer agent 111
Correction: Discovery of the First-in-Class GSK-3β/HDAC Dual Inhibitor as Disease-Modifying Agent to Combat Alzheimer's Disease (ACS Medicinal Chemistry Letters (2019) 10: 4 (469−474) DOI: 10.1021/acsmedchemlett.8b00507) 111
Cytotoxicity of Methoctramine and related Spermine analogues 109
Synthetic polyamines as potential amine oxidase inhibitors: a preliminary study. 109
Structure-activity relationships of methoctramine-related polyamines as muscarinic antagonist: Effect of replacing the inner polymethylene chain with cyclic moieties 108
Progress in acetylcholinesterase inhibitors for Alzheimer's disease: an update 108
Inhibition of Acetylcholinesterase, Beta-Amyloid Aggregation, and NMDA Receptors in Alzheimer's Disease: A Promising Direction for the Multi-target-Directed Ligands Gold Rush 107
Design, Synthesis, and biological evaluation of naphtalene diimides derivatives as anticancer agent 107
null 107
null 106
Preliminary evaluation of the cytotoxicity of naphthalene diimide-polyamine conjugates in human cancer cells 104
null 104
Progress in acetylcholinesterase inhibitors for Alzheimer's disease 103
Multifunctional Tacrine Derivatives in Alzheimer’s Disease 103
A rational design of new multi-target-directed-ligands for the treatment of Alzheimer's disease 102
Synthesis of Monomeric Derivatives To Probe Memoquin's Bivalent Interactions 102
MTDL design strategy in the context of Alzheimer's disease: from lipocrine to memoquin and beyond 101
From dual binding site acetylcholinesterase inhibitors to multi-target-directed ligands (MTDLs): a step forward in the treatment of Alzheimer's disease 100
Multi-Target-Direcetd Ligands as acetylcholinesterase inhibitors and nicotinic modulators for Alzheimer's disease 98
In vitro and in vivo evaluation of polymethylene tetraamine derivatives as NMDA receptor channel blockers 98
Cystamine-tacrine dimer: a new multi-target-directed ligand as potential therapeutic agent for Alzheimer’s disease treatment 97
Methoctramine analogues inhibit responses to capsaicin and protons in rat dorsal root ganglion neurons 97
NEWLY SYNTHESIZED POLYAMINE DERIVATIVES AS POTENTIAL ANTICANCER AGENTS 96
Design, synthesis, and biological evaluation of substituted naphtalene imides and diimides as anticancer agents 96
Structure-Activity Relationships of New Acetylcholinesterase Noncovalent Inhibitors Based on a Polyamine Backbone 95
null 94
Discovery of multipotent drugs for the teratment of Alzheimer's disease 93
Lipoic acid, a lead structure for multi-target-directed drugs for neurodegeneration 93
Structure-Activity Relationships of Acetylcholinesterase Noncovalent Inhibitors Based on a Polyamine Backbone. 4. Futher Investigation on the Inner Spacer. 92
Novel polyamine analogues: from substrates towards potential inhibitors of monoamine oxidases 92
Polymethylene tetraamine backbone as template for the development of biologically active polyamines 91
Synthetic polyamines: an overview of their multiple biological activities. 91
Cytotoxicity of methoctramine-related polyamines 90
Rational design of multitarget-directed antioxidants: merging memoquin and lipocrine molecular frameworks 90
One-molecule-multiple-target strategy: a novel multifunctional molecule designed to block EGF-r and to exert pro-apoptotic effects 89
Synthetic polyamines as potential amine oxidases inhibitors: a preliminary study 89
Inibitori delle fosfodiesterasi 88
Tacrine Derivatives and Alzheimer's Disease 87
Bovine Serum Amine Oxidase and Polyamine Analogues: Chemical Synthesis and Biological Evaluation Integrated with Molecular Docking and 3-D QSAR Studies 84
Novel polyamine analogues: from substrates towards potential inhibitors of monoamine oxidases. 84
Polyamines in Drug Discovery: From the Universal Template Approach to the Multitarget-Directed Ligand Design Strategy 84
Recent advances in the design and synthesis of prazosin derivatives 84
Development of an UHPLC-diode arrays detector (DAD) method for the analysis of polydatin in human plasma 84
Combined Methodologies for Determining In Vitro Bioavailability of Drugs and Prediction of In Vivo Bioequivalence From Pharmaceutical Oral Formulations 84
Recent advances in alpha1-adrenoreceptor antagonists as pharmacological tools and therapeutic agents. 83
null 83
Multi-target-directed drug design strategy: quinone derivatives designed to block amyloid-beta aggregation and to exert antioxidant effects 81
Methoctramine effects on nicotinic acetylcholine receptor kinetics 80
Methoctramine-related polyamines as antinociceptive agents 78
Methoctramine analogues inhibit responses to capsaicin in DRG neurons and cloned TRPV1 78
Combined inhibition of the EGFR/AKT pathways by a novel conjugate of quinazoline with isothiocyanate. 78
Methoctramine analogues inhibit capsaicin induced currents in dorsal root ganglia and Xenopus oocytes expressing TRPV1 77
Multi-Target-Directed Drug Design Strategy: Development of new Naphthalene Diimides Bearing Isothiocyanate Functionality As Anticancer Agents 77
null 76
Synthesis of monomeric derivatives to probe Memoquin bivalent interactions 74
Novel asymmetric naphthalenediimide-polyamines conjugates as anticancer agents. 68
Effect of polyamines on the nicotinic ACh receptor 68
Polyamines analogs and transglutaminase effects on apical growth of the pollen tube 67
Interactions between new polyamine analogs and bovine serum amine oxidase. 67
Exploiting RNA as anticancer target for synthetic polyamines 66
Polyamines, their analogs, and transglutaminase effects on apical growth of the pollen tube 64
Evaluation of the inhibitory potency of a new series of AChE-inhibitors by using a monolithic AChE-micro-IMER 64
Design, synthesis and biological evaluation of new naphtalene diimides bearing isothiocyanate functionality 64
Integrated analytical approaches for the characterization of Spirulina and Chlorella microalgae 64
A kinetic study of new polyamine analogs oxidized by bovine serum amine oxidase . 63
Farmaci Tiroidei 61
Polyamine effects on apical growth of the pollen tube 60
Oxidative deamination of new polyamine analogs by bovine serum amine oxidase: a kinetic study 58
Novel polyamine-based Histone deacetylases-Lysine demethylase 1 dual binding inhibitors 56
Application of an ESI-QTOF method for the detailed characterization of GSK-3β inhibitors 55
Naphthalene diimide-polyamine hybrids as antiproliferative agents: Focus on the architecture of the polyamine chains 53
First in Class Dual Non-ATP-Competitive Glycogen Synthase Kinase 3β/Histone Deacetylase Inhibitors as a Potential Therapeutic to Treat Alzheimer’s Disease 49
Totale 10.623
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Categoria #
all - tutte 28.833
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 805
Totale 29.638
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201.809 0 0 0 0 207 211 282 361 292 156 146 154
2020/20211.420 317 100 38 79 57 97 51 153 159 88 74 207
2021/20221.873 109 59 119 134 164 125 53 138 97 193 347 335
2022/20231.891 219 249 89 224 113 119 101 99 334 60 186 98
2023/20241.004 45 112 78 83 83 193 44 88 55 59 86 78
2024/20251.582 152 348 324 213 545 0 0 0 0 0 0 0
Totale 11.169