CRIS Current Research Information System

TUMIATTI, VINCENZO
 Distribuzione geografica
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Continente #
NA - Nord America 4.134
EU - Europa 4.075
AS - Asia 952
AF - Africa 273
SA - Sud America 22
OC - Oceania 6
Continente sconosciuto - Info sul continente non disponibili 2
Totale 9.464
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Nazione #
US - Stati Uniti d'America 4.124
IT - Italia 1.331
GB - Regno Unito 933
CN - Cina 490
DE - Germania 410
SE - Svezia 404
UA - Ucraina 290
IN - India 193
FR - Francia 163
IE - Irlanda 132
RU - Federazione Russa 121
TG - Togo 106
VN - Vietnam 90
SG - Singapore 75
EE - Estonia 71
ZA - Sudafrica 65
CI - Costa d'Avorio 64
BG - Bulgaria 45
JO - Giordania 31
BE - Belgio 24
SC - Seychelles 23
HR - Croazia 21
ES - Italia 20
CH - Svizzera 18
FI - Finlandia 16
PL - Polonia 16
JP - Giappone 14
BR - Brasile 12
GR - Grecia 11
IR - Iran 10
KR - Corea 10
NL - Olanda 10
TR - Turchia 10
CA - Canada 9
CZ - Repubblica Ceca 8
NG - Nigeria 8
AT - Austria 6
LB - Libano 6
RO - Romania 5
AU - Australia 4
CL - Cile 4
MT - Malta 4
PT - Portogallo 4
ID - Indonesia 3
MY - Malesia 3
PK - Pakistan 3
SK - Slovacchia (Repubblica Slovacca) 3
TW - Taiwan 3
DK - Danimarca 2
DZ - Algeria 2
EC - Ecuador 2
EU - Europa 2
HK - Hong Kong 2
MA - Marocco 2
NZ - Nuova Zelanda 2
SM - San Marino 2
TH - Thailandia 2
AE - Emirati Arabi Uniti 1
AL - Albania 1
AZ - Azerbaigian 1
BD - Bangladesh 1
BO - Bolivia 1
CO - Colombia 1
CR - Costa Rica 1
EG - Egitto 1
FK - Isole Falkland (Malvinas) 1
HU - Ungheria 1
IL - Israele 1
IQ - Iraq 1
LK - Sri Lanka 1
LU - Lussemburgo 1
MD - Moldavia 1
MU - Mauritius 1
NO - Norvegia 1
PE - Perù 1
SA - Arabia Saudita 1
TN - Tunisia 1
Totale 9.464
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Città #
Southend 849
Fairfield 533
Chandler 378
Ashburn 355
Houston 264
Woodbridge 243
Wilmington 236
Seattle 223
Princeton 203
Ann Arbor 199
Bologna 197
Jacksonville 196
Cambridge 178
Dublin 132
Lomé 106
Padova 96
Nanjing 87
Westminster 87
Abidjan 64
Berlin 56
New York 54
Dong Ket 52
Jinan 50
Singapore 49
Rome 48
Milan 45
Saint Petersburg 45
Shenyang 44
Sofia 44
Medford 42
Redmond 41
Hebei 36
Mülheim 33
Turin 33
Amman 31
Beijing 31
Cesena 30
San Diego 30
Nanchang 29
Changsha 27
Los Angeles 27
Redwood City 24
Tianjin 24
Falls Church 23
Mahé 22
Brussels 21
Palermo 21
Haikou 20
Forlì 19
Rimini 19
Des Moines 18
Bremen 17
Hangzhou 15
Jiaxing 15
Taiyuan 15
Boardman 14
Helsinki 14
Norwalk 14
Zhengzhou 14
Guangzhou 13
Ravenna 13
Benevento 12
Dearborn 12
Florence 10
Olalla 10
Parma 10
Ancona 9
Bern 9
Chicago 9
Dallas 9
Hyderabad 9
Modena 9
Naples 9
Ningbo 9
Abeokuta 8
Chiampo 8
Cormano 8
Paris 8
Verona 8
Barcelona 7
Lanzhou 7
Mohali 7
Pisa 7
São Paulo 7
Tokyo 7
Bühl 6
Caserta 6
Cervia 6
Fremont 6
Fuzhou 6
Genoa 6
Genova 6
Mountain View 6
Pune 6
Reggio Emilia 6
San Venanzo 6
Taizhou 6
Tappahannock 6
Warsaw 6
Andover 5
Totale 6.155
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Nome #
Trasportatori di membrana dei farmaci 530
Discovery of the First-in-Class GSK-3β/HDAC Dual Inhibitor as Disease-Modifying Agent To Combat Alzheimer's Disease. 230
Progettazione e sintesi di analoghi rigidi di metoctramina nello studio dei recettori muscarinici 188
Cytotoxicity of methoctramine and methoctramine-related polyamines. 164
Targeting topoisomerase II with trypthantrin derivatives: Discovery of 7-((2-(dimethylamino)ethyl)amino)indolo[2,1-b]quinazoline-6,12-dione as an antiproliferative agent and to treat cancer 162
Structure-activity relationships of acetylcholinesterase noncovalent inhibitors based on a polyamine backbone. 3. Effect of replacing the inner polymethylene chain with cyclic moieties 151
Bis(7)-tacrine Derivatives as Multitarget-Directed Ligands: Focus on Anticholinesterase and Antiamyloid Activities 150
Progettazione e sintesi di poliammine a potenziale attività antitumorale 147
null 141
DESIGN, SYNTHESIS AND BIOLOGICAL EVALUATION OF SUSTITUTED NAPHTHALENE IMIDES AND DIIMIDES AS ANTICANCER AGENT 140
null 135
Structure-activity relationships of novel substituted naphthalene diimides as anticancer agents 130
Cystamine-tacrine dimer: A new multi-target-directed ligand as potential therapeutic agent for Alzheimer's disease treatment. 128
Glycogen Synthase Kinase 3β: A New Gold Rush in Anti-Alzheimer’s Disease Multitarget Drug Discovery? 125
Progettazione e sintesi di derivati poliamminici per il trattamento della malattia di Alzheimer 123
Design, synthesis, and biological evaluation of prazosin-related derivatives as multipotent compounds 122
Design, synthesis, and biological evaluation of pirenzepine analogs bearing a 1,2-cyclohexanediamine and a perhydroquinoxaline units in exchange for the piperazine ring as antimuscarinics 116
Natural polyamines and synthetic analogs modify the growth and the morphology of Pyrus communis pollen tubes affecting ROS levels and causing cell death 114
Study of the cytotoxic effects of the new synthetic isothiocyanate CM9 and its fullerene derivative on human T-leukemia cells 109
Novel bis(7)-tacrine derivatives as multitarget ligands: focus on anti-cholinesterase and anti-amyloid activities 108
Novel Class of Quinone-Bearing Polyamines as Multi-Target-Directed Ligands To Combat Alzheimer's Disease 108
null 107
Exploring the effects of isothiocyanates on chemotherapeutic drugs 107
null 106
Correction: Discovery of the First-in-Class GSK-3β/HDAC Dual Inhibitor as Disease-Modifying Agent to Combat Alzheimer's Disease (ACS Medicinal Chemistry Letters (2019) 10: 4 (469−474) DOI: 10.1021/acsmedchemlett.8b00507) 105
Heterocyclic inhibitors of AChE acylation and peripheral sites. 104
Macrocyclic naphthalene diimides as G-quadruplex binders 104
null 104
Multitarget-directed ligands: Innovative chemical probes and therapeutic tools against Alzheimer's disease 104
Exploiting RNA as a new biomolecular target for synthetic polyamines 102
Cytotoxicity of Methoctramine and related Spermine analogues 101
Synthetic polyamines activating autophagy: Effects on cancer cell death 101
Multi-target-Directed Ligands To Combat Neurodegenerative Diseases 100
Progress in acetylcholinesterase inhibitors for Alzheimer's disease: an update 100
Preparation, characterization and in vitro evaluation of sterically stabilized liposome containing a naphthalenediimide derivative as anticancer agent 100
Structure-activity relationships of methoctramine-related polyamines as muscarinic antagonist: Effect of replacing the inner polymethylene chain with cyclic moieties 99
Progress in acetylcholinesterase inhibitors for Alzheimer's disease 98
Design, Synthesis, and biological evaluation of naphtalene diimides derivatives as anticancer agent 97
Preliminary evaluation of the cytotoxicity of naphthalene diimide-polyamine conjugates in human cancer cells 97
Inhibition of Acetylcholinesterase, Beta-Amyloid Aggregation, and NMDA Receptors in Alzheimer's Disease: A Promising Direction for the Multi-target-Directed Ligands Gold Rush 96
Synthesis of Monomeric Derivatives To Probe Memoquin's Bivalent Interactions 96
A rational design of new multi-target-directed-ligands for the treatment of Alzheimer's disease 95
null 94
Synthetic polyamines as potential amine oxidase inhibitors: a preliminary study. 93
From dual binding site acetylcholinesterase inhibitors to multi-target-directed ligands (MTDLs): a step forward in the treatment of Alzheimer's disease 90
Multifunctional Tacrine Derivatives in Alzheimer’s Disease 88
Methoctramine analogues inhibit responses to capsaicin and protons in rat dorsal root ganglion neurons 88
Multi-Target-Direcetd Ligands as acetylcholinesterase inhibitors and nicotinic modulators for Alzheimer's disease 87
MTDL design strategy in the context of Alzheimer's disease: from lipocrine to memoquin and beyond 87
In vitro and in vivo evaluation of polymethylene tetraamine derivatives as NMDA receptor channel blockers 87
Cystamine-tacrine dimer: a new multi-target-directed ligand as potential therapeutic agent for Alzheimer’s disease treatment 87
Lipoic acid, a lead structure for multi-target-directed drugs for neurodegeneration 87
Design, synthesis, and biological evaluation of substituted naphtalene imides and diimides as anticancer agents 85
NEWLY SYNTHESIZED POLYAMINE DERIVATIVES AS POTENTIAL ANTICANCER AGENTS 84
Discovery of multipotent drugs for the teratment of Alzheimer's disease 83
null 83
Novel polyamine analogues: from substrates towards potential inhibitors of monoamine oxidases 83
Structure-Activity Relationships of Acetylcholinesterase Noncovalent Inhibitors Based on a Polyamine Backbone. 4. Futher Investigation on the Inner Spacer. 82
Structure-Activity Relationships of New Acetylcholinesterase Noncovalent Inhibitors Based on a Polyamine Backbone 82
Polymethylene tetraamine backbone as template for the development of biologically active polyamines 81
Synthetic polyamines as potential amine oxidases inhibitors: a preliminary study 81
Rational design of multitarget-directed antioxidants: merging memoquin and lipocrine molecular frameworks 81
Cytotoxicity of methoctramine-related polyamines 80
Synthetic polyamines: an overview of their multiple biological activities. 80
One-molecule-multiple-target strategy: a novel multifunctional molecule designed to block EGF-r and to exert pro-apoptotic effects 79
Inibitori delle fosfodiesterasi 79
Tacrine Derivatives and Alzheimer's Disease 78
null 76
Polyamines in Drug Discovery: From the Universal Template Approach to the Multitarget-Directed Ligand Design Strategy 76
Recent advances in alpha1-adrenoreceptor antagonists as pharmacological tools and therapeutic agents. 75
Recent advances in the design and synthesis of prazosin derivatives 74
Combined Methodologies for Determining In Vitro Bioavailability of Drugs and Prediction of In Vivo Bioequivalence From Pharmaceutical Oral Formulations 73
Methoctramine effects on nicotinic acetylcholine receptor kinetics 72
Multi-target-directed drug design strategy: quinone derivatives designed to block amyloid-beta aggregation and to exert antioxidant effects 71
Methoctramine-related polyamines as antinociceptive agents 69
Methoctramine analogues inhibit responses to capsaicin in DRG neurons and cloned TRPV1 68
Novel polyamine analogues: from substrates towards potential inhibitors of monoamine oxidases. 68
Methoctramine analogues inhibit capsaicin induced currents in dorsal root ganglia and Xenopus oocytes expressing TRPV1 67
Development of an UHPLC-diode arrays detector (DAD) method for the analysis of polydatin in human plasma 64
Bovine Serum Amine Oxidase and Polyamine Analogues: Chemical Synthesis and Biological Evaluation Integrated with Molecular Docking and 3-D QSAR Studies 63
Synthesis of monomeric derivatives to probe Memoquin bivalent interactions 63
Multi-Target-Directed Drug Design Strategy: Development of new Naphthalene Diimides Bearing Isothiocyanate Functionality As Anticancer Agents 60
Combined inhibition of the EGFR/AKT pathways by a novel conjugate of quinazoline with isothiocyanate. 58
Effect of polyamines on the nicotinic ACh receptor 57
Interactions between new polyamine analogs and bovine serum amine oxidase. 56
Exploiting RNA as anticancer target for synthetic polyamines 56
A kinetic study of new polyamine analogs oxidized by bovine serum amine oxidase . 55
Integrated analytical approaches for the characterization of Spirulina and Chlorella microalgae 54
Polyamines, their analogs, and transglutaminase effects on apical growth of the pollen tube 52
Polyamine effects on apical growth of the pollen tube 52
Evaluation of the inhibitory potency of a new series of AChE-inhibitors by using a monolithic AChE-micro-IMER 52
Novel asymmetric naphthalenediimide-polyamines conjugates as anticancer agents. 50
Polyamines analogs and transglutaminase effects on apical growth of the pollen tube 48
Application of an ESI-QTOF method for the detailed characterization of GSK-3β inhibitors 47
Oxidative deamination of new polyamine analogs by bovine serum amine oxidase: a kinetic study 46
Farmaci Tiroidei 45
Design, synthesis and biological evaluation of new naphtalene diimides bearing isothiocyanate functionality 44
Novel polyamine-based Histone deacetylases-Lysine demethylase 1 dual binding inhibitors 37
Determination of Bisphenol A as contaminant in microalgae by GC-MS 36
Naphthalene diimide-polyamine hybrids as antiproliferative agents: Focus on the architecture of the polyamine chains 36
Totale 9.473
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Categoria #
all - tutte 24.815
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 644
Totale 25.459
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20202.059 0 72 40 138 207 211 282 361 292 156 146 154
2020/20211.420 317 100 38 79 57 97 51 153 159 88 74 207
2021/20221.873 109 59 119 134 164 125 53 138 97 193 347 335
2022/20231.891 219 249 89 224 113 119 101 99 334 60 186 98
2023/20241.004 45 112 78 83 83 193 44 88 55 59 86 78
2024/2025163 152 11 0 0 0 0 0 0 0 0 0 0
Totale 9.750