POLITO, LETIZIA
 Distribuzione geografica
Continente #
EU - Europa 6.726
NA - Nord America 5.983
AS - Asia 5.476
AF - Africa 403
SA - Sud America 309
OC - Oceania 10
Continente sconosciuto - Info sul continente non disponibili 1
Totale 18.908
Nazione #
US - Stati Uniti d'America 5.910
IT - Italia 2.987
SG - Singapore 1.742
CN - Cina 1.526
VN - Vietnam 989
GB - Regno Unito 910
HK - Hong Kong 546
DE - Germania 543
NL - Olanda 521
SE - Svezia 455
UA - Ucraina 264
IN - India 254
RU - Federazione Russa 223
FR - Francia 212
BR - Brasile 203
CI - Costa d'Avorio 195
IE - Irlanda 167
KR - Corea 115
ZA - Sudafrica 86
FI - Finlandia 85
JP - Giappone 79
EE - Estonia 64
BG - Bulgaria 62
CA - Canada 53
AR - Argentina 49
JO - Giordania 45
BE - Belgio 44
ID - Indonesia 41
ES - Italia 34
AT - Austria 33
TG - Togo 30
IR - Iran 27
SC - Seychelles 24
CH - Svizzera 23
GR - Grecia 23
PH - Filippine 21
NG - Nigeria 20
EG - Egitto 19
PL - Polonia 18
BD - Bangladesh 14
EC - Ecuador 14
IQ - Iraq 14
TR - Turchia 14
CL - Cile 13
RO - Romania 13
MX - Messico 11
LY - Libia 10
LT - Lituania 8
PT - Portogallo 8
UZ - Uzbekistan 8
AE - Emirati Arabi Uniti 7
CO - Colombia 7
PY - Paraguay 7
AU - Australia 6
DZ - Algeria 6
HU - Ungheria 6
MY - Malesia 6
PE - Perù 6
HR - Croazia 5
IL - Israele 4
MA - Marocco 4
PK - Pakistan 4
UY - Uruguay 4
VE - Venezuela 4
CZ - Repubblica Ceca 3
DK - Danimarca 3
NO - Norvegia 3
SA - Arabia Saudita 3
SN - Senegal 3
TW - Taiwan 3
AM - Armenia 2
BO - Bolivia 2
CY - Cipro 2
DO - Repubblica Dominicana 2
GU - Guam 2
HN - Honduras 2
KZ - Kazakistan 2
LB - Libano 2
LK - Sri Lanka 2
MD - Moldavia 2
NZ - Nuova Zelanda 2
SK - Slovacchia (Repubblica Slovacca) 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AL - Albania 1
BW - Botswana 1
ET - Etiopia 1
GH - Ghana 1
GP - Guadalupe 1
GT - Guatemala 1
IS - Islanda 1
JM - Giamaica 1
KE - Kenya 1
KH - Cambogia 1
KW - Kuwait 1
LU - Lussemburgo 1
MT - Malta 1
MU - Mauritius 1
OM - Oman 1
PR - Porto Rico 1
SI - Slovenia 1
Totale 18.905
Città #
Singapore 1.179
Southend 759
Ashburn 602
Fairfield 549
Hong Kong 542
Santa Clara 512
Chandler 503
Bologna 384
Woodbridge 269
Hefei 268
Houston 256
Wilmington 250
Beijing 241
Ho Chi Minh City 226
Seattle 225
Ann Arbor 213
Princeton 212
Abidjan 195
Hanoi 195
Cambridge 194
Dong Ket 186
Jacksonville 182
Boardman 178
Dublin 167
Milan 164
Rome 134
Seoul 110
Turin 110
Nanjing 96
Westminster 87
Padova 86
Los Angeles 83
Berlin 79
Tokyo 72
Jinan 67
Sofia 61
Buffalo 53
Catania 49
Helsinki 49
Saint Petersburg 48
Amman 45
Shenyang 45
Brussels 44
Redondo Beach 41
Medford 40
Hebei 38
Guangzhou 36
Mülheim 36
Nanchang 36
San Diego 36
Falkenstein 35
Florence 35
Redmond 35
Shanghai 35
Frankfurt am Main 33
Lappeenranta 32
Redwood City 32
Zhengzhou 32
Des Moines 31
Naples 31
Lomé 30
Foligno 29
Changsha 28
Dallas 26
Jakarta 26
Modena 26
London 25
Phoenix 24
Verona 24
Tianjin 23
Bengaluru 22
Terni 22
Dearborn 21
New York 21
Abeokuta 20
Hangzhou 20
Ferrara 19
Haiphong 19
São Paulo 19
Toronto 19
Da Nang 18
Hyderabad 18
Bari 17
Mahé 17
Thái Nguyên 17
Bern 16
Biên Hòa 15
Forlì 15
Ha Long 15
Genoa 14
Kunming 14
Nashville 14
Norwalk 14
Nuremberg 14
Vienna 14
Council Bluffs 13
Jiaxing 13
Quận Bình Thạnh 13
Sasso Marconi 13
Taizhou 13
Totale 11.323
Nome #
Scienze e Ricerche 1.279
biomedicines (ISSN 2227-9059) 1.015
Frontiers in Pharmacology 394
Antitumor activity of anti-CD30 immunotoxin (Ber-H2/saporin) in vitro and in severe combined immunodeficiency disease mice xenografted with human CD30+ anaplastic large-cell lymphoma 265
Membrane lipidome reorganization correlates with the fate of neuroblastoma cells supplemented with fatty acids. 214
The 1.4.ANG. structure of dianthin 30 indicates a role of surface potential at the active site of type 1 ribosome inactivating proteins. 203
Apoptosis and necroptosis induced by stenodactylin in neuroblastoma cells can be completely prevented through caspase inhibition plus catalase or necrostatin-1 203
Frontiers in Pharmacology Experimental Pharmacology and Drug Discovery 201
Distribution of RIP activity in tissue extracts from Fragaria x ananassa (strawberry) and its correlation with environmental stress 197
Ribosome-inactivating proteins in edible plants and purification and characterization of a new ribosome-inactivating protein from Cucurbita moschata. 196
Characterization of highly toxic type 2 ribosome-inactivating proteins from Adenia lanceolata and Adenia stenodactyla (Passifloraceae) 194
Ricin: An ancient story for a timeless plant toxin 194
Binding and intracellular routing of the plant-toxic lectins, lanceolin and stenodactylin 190
Survival and death of intestinal cells infected by Chlamydia trachomatis 190
High in vitro anti-tumor efficacy of dimeric rituximab/saporin-S6 immunotoxin 186
Internalization and recycling of ALCAM/CD166 detected by a fully human single-chain recombinant antibody. 183
Structure/function studies on two type 1 ribosome inactivating proteins: Bouganin and lychnin. 183
RIP activity in basic protein fractions of tissue extracts from Fragaria x ananassa 181
Plant Toxin-Based Immunotoxins for Cancer Therapy: A Short Overview 181
Rituximab and other new anti-CD20 mAbs for non-Hodgkin’s lymphoma treatment. 175
Potential therapeutic application of the plant toxin saporin-S6. 175
(ClO4)2: Metallodrug Nanocontainer Delivery and Membrane Lipidomics of a Neuroblastoma Cell Line Coupled with a Liposome Biomimetic Model Focusing on Fatty Acid Reactivity 173
Anti-PD-L1 immunoconjugates for cancer therapy: Are available antibodies good carriers for toxic payload delivering? 171
The 1.4 Å Structure of Dianthin 30 Indicates a Role of Surface Potential at the Active Site of Type 1 Ribosome Inactivating Proteins 169
Saporin-S6: a useful tool in cancer therapy. 168
Immunotoxins and other conjugates: pre-clinical studies. 167
Sequence determination of lychnin, a type 1 ribosome-inactivating protein from Lychnis chalcedonica seeds. 165
Plants Producing Ribosome-Inactivating Proteins in Traditional Medicine 164
ATG-saporin-S6 immunotoxin: a new potent and selective drug to eliminate activated lymphocytes and lymphoma cells. 164
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY 164
Ribosome-inactivating proteins from plants: A historical overview 163
Two Saporin-Containing Immunotoxins Specific for CD20 and CD22 Show Different Behavior in Killing Lymphoma Cells 163
Early Response to the Plant Toxin Stenodactylin in Acute Myeloid Leukemia Cells Involves Inflammatory and Apoptotic Signaling 163
Crystallization and preliminary X-ray diffraction data analysis of stenodactylin, a highly toxic type 2 ribosome-inactivating protein from Adenia stenodactyla. 162
A new potent and selective anti-lymphocytes-immunotoxin for the treatment of GVHD and lymphocyte-derived neoplasms 161
Matricaria genus as a source of antimicrobial agents: From farm to pharmacy and food applications 161
Hyperuricaemia, xanthine oxidoreductase and ribosome-inactivating proteins from plants: The contributions of fiorenzo stirpe to frontline research 159
The fundamental contribution of prof. Stirpe (and his research group) to the broadening of the scientific perspective on xanthine oxidoreductase 155
Endocytosis and intracellular localisation of type 1 ribosome-inactivating protein saporin-s6 155
Anti-tumor activity of Epratuzumab/saporin-S6. 155
Momordica charantia, a nutraceutical approach for inflammatory related diseases 155
CD38 as a target of IB4 mAb carrying saporin-S6: Design of an immunotoxin for ex vivo depletion of hematological CD38+ neoplasia 154
CTLA-4 is constitutively expressed on tumor cells and can trigger apoptosis upon ligand interaction 154
Structural studies on RIPs elucidates the differences in their action on polynucleotides. 153
The role of xanthine oxidoreductase and uric acid in metabolic syndrome 151
Bouganin, an attractive weapon for immunotoxins 151
Immunotoxins and Other Conjugates Containing Saporin-S6 for Cancer Therapy 150
Structure/funcion studies on type 1 ribosome inactivating proteins. 148
Metabolic syndrome and cancer risk: The role of xanthine oxidoreductase 148
Cell interaction of the type 1 RIP Saporin 145
Heterophyllin: A New Adenia Toxic Lectin with Peculiar Biological Properties 144
Plant Toxins as Potential Alternatives to Botulinum Toxin for Eye-Movement Disorder Therapy 144
Due nuove tossine per la chemoablazione sperimentale nello strabismo e nei disordini del movimento (blefarospasmo). 143
Epratuzumab/Saporin-S6: an anti-CD22 immunotoxin for selective depletion of B-cells neoplasms 143
New Insights on Saporin Resistance to Chemical Derivatization with Heterobifunctional Reagents 141
Xanthine Oxidoreductase in Drug Metabolism: Beyond A Role as a Detoxifying Enzyme 141
Hexadecenoic Fatty Acid Positional Isomers and De Novo PUFA Synthesis in Colon Cancer Cells 141
Expression of CTLA-4 in non-human primate lymphocytes and its use as a potential target for specific immunotoxin-mediated apoptosis: results of in vitro studies. 141
Kirkiin: A New Toxic Type 2 Ribosome-Inactivating Protein from the Caudex of Adenia kirkii 141
Cancer Cell & Microenvironment 140
The conjugate Rituximab/saporin-S6 completely inhibits clonogenic growth of CD20 expressing cells and produces a synergistic toxic effect with Fludarabine 139
Antibody conjugates for sarcoma therapy: How far along are we? 139
Targeting CTLA-4 by its recombinant ligands CD80/CD86: Perspectives towards the development of a novel anti-tumor therapeutic approach. 137
Xanthine oxidoreductase: One enzyme for multiple physiological tasks 136
Endocitosi e traffico intracellulare della Saporina-S6 135
Programmed death induced by saporin as compared to ricin in lymphoma cells. 135
Protein synthesis inhibition activity by strawberry tissue protein extracts during plant life cycle and under biotic and abiotic stresses 135
Epratuzumab/saporin-S6: a new anti-CD22 immunotoxin with a potent antitumour activity. 132
Pathophysiology of circulating xanthine oxidoreductase: new emerging roles for a multi-tasking enzyme. 131
mAbs targeting CD20 and other lymphocyte CD markers in lymphoma treatment. 130
Morte cellulare programmataindotta dalle RIP ricina e saporina in cellule linfomatose. 129
Inducible antiviral activity and rapid production of the Ribosome-Inactivating Protein I from Phytolacca heterotepala in tobacco 128
Xanthine oxidoreductase in cancer: more than a differentiation marker 128
Immunoconjugates for Osteosarcoma Therapy: Preclinical Experiences and Future Perspectives 127
Insights into penicillin-induced Chlamydia trachomatis persistence 127
Primi studi sull'attività Rip in fragola. 125
Xanthine Oxidoreductase In Atherosclerosis Pathogenesis: Not Only Oxidative Stress. 125
Epratuzumab/saporina-S6: una immunotossina anti-CD22 per la deplezione delle cellule B linfomatose 122
Intracellular fate of saporin-S6, a putative drug for anti-cancer therapy 121
Research of new ribosome-inactivating proteins from adenina genus (Passifloraceae); characterization of highly toxic type 2 RIPs from Adenia lanceolata and Adenia stenodactyla. 121
Saporin induces multiple death pathways in lymphoma cells with different intensity, timing as compared to ricin. 119
Women’s Special Issue Series: Biomedicines 117
Methods and application in experimental pharmacology and drug discovery: 2021 110
The ATG-saporin-S6 immunotoxin causes a complete depletion of activated T cells. 110
EVALUATION OF PLANT RIBOSOME-INACTIVATING PROTEIN TOXICITY ON INTESTINAL CELLS 109
Distribuzione dell’attività lectinica e tossica in piante appartenenti al genere Adenia (Passifloraceae) 108
Toxin and Immunotoxin Based Therapeutic Approaches 108
Sequence, structure, and binding site analysis of kirkiin in comparison with ricin and other type 2 rips 106
hLL2/saporin: un’immunotossina anti-CD22 con potente attività antitumorale. 105
Anti-Cancer Agents in Medicinal Chemistry 104
L’immunotossina ATG/ saporina-S6 per l’eliminazione specifica di linfociti T attivati. 103
Lifestyle, Oxidative Stress, and Antioxidants: Back and Forth in the Pathophysiology of Chronic Diseases 101
Occupational sensitization to ribosome-inactivating proteins in researchers 100
Primary Sequence and 3D Structure Prediction of the Plant Toxin Stenodactylin 100
null 98
Antibody Based Delivery of Toxins and Other Active Molecules for Cancer Therapy 97
Ribosome-inactivating proteins and other lectins from Adenia (Passifloraceae) 94
null 92
CTLA-4 is not restricted to the lymphoid cell lineage and can function as a target molecule for apoptosis induction of leukemic cells 92
Xanthine Oxidoreductase: A Double-Edged Sword in Neurological Diseases 91
Totale 16.895
Categoria #
all - tutte 50.212
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 50.212


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20211.072 0 0 0 0 0 102 41 110 201 103 106 409
2021/20221.992 127 94 142 134 165 124 46 150 95 101 444 370
2022/20232.427 264 229 126 261 171 182 87 137 508 109 242 111
2023/20241.178 68 137 84 108 86 143 122 120 67 101 65 77
2024/20254.627 222 462 415 385 854 327 400 260 134 282 138 748
2025/20263.890 790 774 619 508 840 359 0 0 0 0 0 0
Totale 19.243