CRIS Current Research Information System

BOLOGNESI, MARIA LAURA
 Distribuzione geografica
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Continente #
NA - Nord America 14.303
AS - Asia 14.036
EU - Europa 11.696
AF - Africa 978
SA - Sud America 939
OC - Oceania 58
Continente sconosciuto - Info sul continente non disponibili 36
Totale 42.046
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Nazione #
US - Stati Uniti d'America 14.108
SG - Singapore 3.813
CN - Cina 3.761
IT - Italia 3.351
VN - Vietnam 2.842
GB - Regno Unito 2.281
DE - Germania 1.326
HK - Hong Kong 1.266
SE - Svezia 829
IN - India 811
FR - Francia 728
BR - Brasile 711
UA - Ucraina 643
RU - Federazione Russa 610
CI - Costa d'Avorio 365
KR - Corea 340
IE - Irlanda 330
JP - Giappone 315
NL - Olanda 282
ZA - Sudafrica 221
TG - Togo 184
EE - Estonia 165
ES - Italia 162
HR - Croazia 159
FI - Finlandia 158
AR - Argentina 105
CA - Canada 105
PH - Filippine 95
PL - Polonia 94
BD - Bangladesh 91
BG - Bulgaria 86
TR - Turchia 85
PK - Pakistan 84
ID - Indonesia 79
SC - Seychelles 78
CH - Svizzera 65
PT - Portogallo 62
IQ - Iraq 61
GR - Grecia 59
BE - Belgio 58
MX - Messico 58
AT - Austria 57
TW - Taiwan 57
TH - Thailandia 55
AU - Australia 52
IR - Iran 49
JO - Giordania 47
CZ - Repubblica Ceca 39
EC - Ecuador 35
MY - Malesia 35
RO - Romania 34
NG - Nigeria 32
SA - Arabia Saudita 31
EU - Europa 30
CO - Colombia 25
DK - Danimarca 24
CL - Cile 22
UZ - Uzbekistan 22
MA - Marocco 18
EG - Egitto 17
PY - Paraguay 17
SI - Slovenia 16
TN - Tunisia 16
IL - Israele 15
LB - Libano 14
NO - Norvegia 13
AE - Emirati Arabi Uniti 12
AL - Albania 12
NP - Nepal 12
KE - Kenya 9
LT - Lituania 9
BY - Bielorussia 8
DZ - Algeria 8
PE - Perù 8
KZ - Kazakistan 7
LV - Lettonia 7
VE - Venezuela 7
AZ - Azerbaigian 6
JM - Giamaica 6
SN - Senegal 6
DO - Repubblica Dominicana 5
HN - Honduras 5
HU - Ungheria 5
NZ - Nuova Zelanda 5
UY - Uruguay 5
A2 - ???statistics.table.value.countryCode.A2??? 4
BO - Bolivia 4
CM - Camerun 4
CR - Costa Rica 4
CU - Cuba 4
ET - Etiopia 4
KG - Kirghizistan 4
KH - Cambogia 4
MD - Moldavia 4
OM - Oman 4
AO - Angola 3
BA - Bosnia-Erzegovina 3
GH - Ghana 3
MM - Myanmar 3
MU - Mauritius 3
Totale 41.995
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Città #
Singapore 2.684
Southend 1.892
Ashburn 1.306
Fairfield 1.283
Hong Kong 1.163
Chandler 952
Bologna 813
San Jose 736
Ho Chi Minh City 668
Woodbridge 639
Houston 623
Wilmington 618
Santa Clara 608
Hefei 581
Ann Arbor 571
Hanoi 566
Seattle 551
Princeton 493
Cambridge 484
Beijing 446
Jacksonville 418
Abidjan 365
Boardman 349
Dublin 330
Lauterbourg 279
Milan 278
Los Angeles 269
Dong Ket 250
Seoul 247
Tokyo 241
Nanjing 203
Westminster 203
Padova 188
Lomé 184
Berlin 181
Dallas 174
Buffalo 142
New York 135
Helsinki 125
Jinan 125
Turin 104
Saint Petersburg 103
Council Bluffs 101
Guangzhou 98
Medford 95
Shenyang 92
Da Nang 90
Nanchang 87
São Paulo 85
San Diego 84
Changsha 83
Mülheim 83
Redmond 83
Frankfurt am Main 82
Haiphong 80
Shanghai 80
Florence 78
Bengaluru 76
Sofia 76
Redondo Beach 74
Rome 72
Dearborn 71
Hebei 71
Des Moines 68
Redwood City 66
Munich 64
Stockholm 62
Chicago 61
Tianjin 58
Falls Church 56
Zhengzhou 54
Mahé 52
Hangzhou 50
Hyderabad 49
Madrid 49
London 48
Amman 46
Brussels 46
Johannesburg 45
Nuremberg 43
Amsterdam 42
Phoenix 42
Yubileyny 42
Jiaxing 41
Shenzhen 38
Jakarta 37
Warsaw 36
Barcelona 34
Verona 34
Bremen 33
Brooklyn 32
Cesena 32
Sydney 32
Modena 30
Olalla 30
Can Tho 29
Lisbon 29
Siracusa 29
Taizhou 29
Bern 28
Totale 25.907
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Nome #
A small molecule targeting the multifactorial nature of Alzheimer's disease 511
A Focused Library of Psychotropic Analogues with Neuroprotective and Neuroregenerative Potential 438
3,4-Dihydro-1,3,5-triazin-2(1H)-ones as the First Dual BACE-1/GSK-3β Fragment Hits against Alzheimer's Disease 423
PROTAC-Induced Glycogen Synthase Kinase 3β Degradation as a Potential Therapeutic Strategy for Alzheimer’s Disease 331
Design and synthesis of small molecules targeting pre-miRNA21 toward the development of ribonuclease targeting chimeras (RIBOTACs) to regulate the oncogenic miRNA21 317
2-Phenoxy-1,4-naphthoquinones: From a Multitarget Antitrypanosomal to a Potential Antitumor Profile 309
Enriching Proteolysis Targeting Chimeras with a Second Modality: When Two Are Better Than One 300
Bis(7)-tacrine Derivatives as Multitarget-Directed Ligands: Focus on Anticholinesterase and Antiamyloid Activities 297
Fragment Merging, Growing, and Linking Identify New Trypanothione Reductase Inhibitors for Leishmaniasis 296
Targeted Protein Degradation for Infectious Diseases: from Basic Biology to Drug Discovery 289
Changing paradigm to target microglia in neurodegenerative diseases: from anti-inflammatory strategy to active immunomodulation. 279
Quinolinetrione-tacrine hybrids as multi-target-directed ligands against Alzheimer's disease 273
Discovery of Dual Aβ/Tau Inhibitors and Evaluation of Their Therapeutic Effect on a Drosophila Model of Alzheimer's Disease 271
Tau-Centric Multitarget Approach for Alzheimer's Disease: Development of First-in-Class Dual Glycogen Synthase Kinase 3β and Tau-Aggregation Inhibitors 257
A small chemical library of 2-aminoimidazole derivatives as BACE-1 inhibitors: structure-based design, synthesis, and biological evaluation 255
Sustainable Drug Discovery of Multi-Target-Directed Ligands for Alzheimer's Disease 254
Molecular hybridization as a tool for designing multitarget drug candidates for complex diseases 250
Novel Sustainable-by-Design HDAC Inhibitors for the Treatment of Alzheimer's Disease 243
Progettazione e sintesi di analoghi rigidi di metoctramina nello studio dei recettori muscarinici 237
Bifunctional carbazole derivatives for simultaneous therapy and fluorescence imaging in prion disease murine cell models 235
PROTAC-INDUCED GLYCOGEN SYNTHASE KINASE 3B DEGRADATION 235
Design and in vitro study of a dual drug-loaded delivery system produced by electrospinning for the treatment of acute injuries of the central nervous system 235
Integrating a quinone substructure into histone deacetylase inhibitors to cope with Alzheimer's disease and cancer 233
A NEW EPIDERMAL GROWTH FACTOR RECEPTOR INHIBITOR IN COLON CANCER CELLS 227
Novel tacrine-tryptophan hybrids: Multi-target directed ligands as potential treatment for Alzheimer's disease 227
N-1,2,3-triazole-isatin derivatives for cholinesterase and β-amyloid aggregation inhibition: A comprehensive bioassay study 227
Progettazione e sintesi di poliammine a potenziale attività antitumorale 226
From combinations to multitarget-directed ligands: A continuum in Alzheimer's disease polypharmacology 226
Nutritional and Pharmacological Strategies to Regulate Microglial Polarization in Cognitive Aging and Alzheimer's Disease. 222
α-linolenic acid-valproic acid conjugates: Toward single-molecule polypharmacology for multiple sclerosis 221
Discovery of Sustainable Drugs for Neglected Tropical Diseases: Cashew Nut Shell Liquid (CNSL)-Based Hybrids Target Mitochondrial Function and ATP Production in Trypanosoma brucei 217
A new EGFR inhibitor induces apoptosis in colon cancer cells. 216
Rational Approach to discover multipotent anti-Alzheimer drugs 214
Accelerating Drug Discovery Efforts for Trypanosomatidic Infections Using an Integrated Transnational Academic Drug Discovery Platform 214
Electrospun fibers for a local release of an anti-inflammatory and a promyelinating drug 213
Harnessing the 12 Green Chemistry Principles for Sustainable Antiparasitic Drugs: Toward the One Health Approach 212
Sustainable production of pharmaceutical, nutraceutical and bioactive compounds from biomass and waste 210
STUDY OF THE ANTI-INFLAMMATORY ACTIVITY OF NOVEL TACRINE DERIVATIVES WITH LIPIDS EXTRACTED FROM CASHEW NUT SHELL LIQUID 208
Curcumin analogs as multi-target antioxidants: focus on mitochondria. 207
Click Chemistry and Targeted Degradation: A Winning Combination for Medicinal Chemists? 204
Targeting Lewy body dementia with neflamapimod-rasagiline hybrids 203
Polyamine conjugation of curcumin analogues toward the discovery of mitochondria-directed neuroprotective agents. 203
Development of a Focused Library of Triazole-Linked Privileged-Structure-Based Conjugates Leading to the Discovery of Novel Phenotypic Hits against Protozoan Parasitic Infections 202
Journal of Medicinal Chemistry 201
Capitolo 2. Proprietà chimico-fisiche e attività biologica 200
Design, synthesis, and biological evaluation of conformationally restricted rivastigmine analogues 199
Multitarget Drug Design Strategy: Quinone–Tacrine Hybrids Designed To Block Amyloid-β Aggregation and To Exert Anticholinesterase and Antioxidant Effects 198
Turning Donepezil into a Multi-Target-Directed Ligand through a Merging Strategy 198
Discovery of sustainable drugs for Alzheimer's disease: cardanol-derived cholinesterase inhibitors with antioxidant and anti-amyloid properties 197
Progettazione e sintesi di derivati poliamminici per il trattamento della malattia di Alzheimer 193
Alzheimer's disease: new approaches to drug discovery. 193
Multitargeted drugs discovery: Balancing anti-amyloid and anticholinesterase capacity in a single chemical entity 192
Phenothiazine-Tacrine Heterodimers: Pursuing Multitarget Directed Approach in Alzheimer's Disease 192
Riluzole-Rasagiline Hybrids: Toward the Development of Multi-Target-Directed Ligands for Amyotrophic Lateral Sclerosis 191
BACE-1 Inhibitors: From Recent Single-Target Molecules to Multitarget Compounds for Alzheimer's Disease 189
A NEW EPIDERMAL GROWTH FACTOR RECEPTOR INHIBITOR IN COLON CANCER CELLS 189
Complementary medicinal chemistry-driven strategies toward new antitrypanosomal and antileishmanial lead drug candidates 187
Novel multi target-directed ligands targeting 5-HT4 receptors with in cellulo antioxidant properties as promising leads in Alzheimer's disease 187
Novel multifunctional tacrine–donepezil hybrids against Alzheimer's disease: Design synthesis and bioactivity studies 185
Targeting RNA degradation with small molecules: design and synthesis of selective RNA binders and development of ribonuclease targeting chimeras (RIBOTACs) 183
Structure-activity relationships of memoquin: Influence of the chain chirality in the multi-target mechanism of action 179
Cystamine-tacrine dimer: A new multi-target-directed ligand as potential therapeutic agent for Alzheimer's disease treatment. 178
New tacrine dimers with antioxidant linkers as dual drugs: Anti-Alzheimer's and antiproliferative agents 177
A Fluorescent Styrylquinoline with Combined Therapeutic and Diagnostic Activities against Alzheimer's and Prion Diseases 174
Novel bis(7)-tacrine derivatives as multitarget ligands: focus on anti-cholinesterase and anti-amyloid activities 173
Medicinal Chemistry of Hybrids for Neurodegenerative Diseases 173
Bivalent tacrine-based acetylcholinesterase inhibitors: role of the spacer in the recognition process of the enzyme gorge 171
Toward a rational design of multitarget-directed antioxidants: merging memoquin and lipoic acid molecular frameworks 171
From combinations to single-molecule polypharmacology—cromolyn-ibuprofen conjugates for alzheimer’s disease 171
Parallel Synthesis, Evaluation, and Preliminary Structure-Activity Relationship of 2,5-Diamino-1,4-benzoquinones as a Novel Class of Bivalent Anti-Prion Compound. 170
Multi-Target-Directed Drug Design Strategy: From a Dual Binding Site Acetylcholinesterase Inhibitor to a Trifunctional Compound against Alzheimer's Disease 169
The concept of privileged structures in rational drug design: Focus on acridine and quinoline scaffolds in neurodegenerative and protozoan diseases 169
Tacripyrimidines, the first tacrine-dihydropyrimidine hybrids, as multi-target-directed ligands for Alzheimer's disease 167
Targeting Tau Protein with Proximity Inducing Modulators: A New Frontier to Combat Tauopathies 165
Design, synthesis, and biological evaluation of pirenzepine analogs bearing a 1,2-cyclohexanediamine and a perhydroquinoxaline units in exchange for the piperazine ring as antimuscarinics 165
Hybrid Lipoic Acid Derivatives to Attack Prion Disease on Multiple Fronts 165
Process for preparation of 1,4-benzoquinone-2,5-diamines by reaction of amines with 1,4-benzoquinones bearing leaving groups at the 2- and 5-positions 164
Multitarget Ligands in the Search for Novel Lead Candidates against Trypanosoma and Leishmania 164
A General Protocol for the Solvent- and Catalyst-Free Synthesis of 2-Styrylquinolines under Focused Microwave Irradiation 164
Navigating the Chemical Space of Multitarget-Directed Ligands: From Hybrids to Fragments in Alzheimer's Disease 164
Quinones bearing non-steroidal anti-inflammatory fragments as multitarget ligands for Alzheimer’s disease 163
Cashew nut shell liquid (Cnsl) as a source of drugs for alzheimer’s disease 163
Multitarget-directed ligands: Innovative chemical probes and therapeutic tools against Alzheimer's disease 163
Conjugation of Quinones with Natural Polyamines: Toward an Expanded Antitrypanosomatid Profile 161
Inhibition of Acetylcholinesterase, Beta-Amyloid Aggregation, and NMDA Receptors in Alzheimer's Disease: A Promising Direction for the Multi-target-Directed Ligands Gold Rush 160
Editorial: Multi-target-directed ligands (MTDL) as challenging research tools in drug discovery: From design to pharmacological evaluation 160
Multitarget Drug Discovery and Polypharmacology 159
Novel Class of Quinone-Bearing Polyamines as Multi-Target-Directed Ligands To Combat Alzheimer's Disease 158
Privileged structure-guided synthesis of quinazoline derivatives as inhibitors of trypanothione reductase 157
Mitochondria-directed antioxidants in Alzheimer's disease. 156
A perspective on multi-target drug discovery and design for complex diseases 156
Benign-by-Design SAHA Analogues for Human and Animal Vector-Borne Parasitic Diseases 155
Progress in acetylcholinesterase inhibitors for Alzheimer's disease: an update 155
Design, synthesis, and biological evaluation of substituted 2,3-dihydro-1H-cyclopenta[b]quinolin-9-ylamine related compounds as fructose-1,6-bisphosphatase inhibitors 154
Synthesis of Monomeric Derivatives To Probe Memoquin's Bivalent Interactions 154
Exploiting the lipoic acid structure in the search for novel multitarget ligands against Alzheimer's disease. 154
Analysis of the muscarinic receptor subtype mediating inhibition of the neurogenic contractions in rabbit isolated vas deferens by a series of polymethylene tetra-amines 153
Investigation of the photostability properties of memoquin, a quinone derivative for the treatment of Alzheimer's disease. 153
Multitargeted drugs for the treatment of Alzheimer's disease 153
Drug Discovery Strategies for the Generation of Multitarget Ligands against Neglected Tropical Diseases 153
Totale 20.874
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Categoria #
all - tutte 113.977
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 308
Totale 114.285
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20211.106 0 0 0 0 0 0 0 0 0 235 193 678
2021/20224.476 519 137 255 273 451 337 134 296 223 294 798 759
2022/20234.733 470 671 272 528 332 331 200 348 703 151 457 270
2023/20241.988 130 243 156 174 166 297 117 136 98 174 164 133
2024/20256.434 388 908 663 390 1.028 344 387 247 206 372 351 1.150
2025/202613.833 1.038 1.446 1.382 1.192 1.636 924 1.982 616 2.872 745 0 0
Totale 42.824