CRIS Current Research Information System

BOLOGNESI, MARIA LAURA
 Distribuzione geografica
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Continente #
NA - Nord America 15.952
AS - Asia 14.380
EU - Europa 12.076
SA - Sud America 995
AF - Africa 988
Continente sconosciuto - Info sul continente non disponibili 820
OC - Oceania 60
Totale 45.271
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Nazione #
US - Stati Uniti d'America 15.621
SG - Singapore 3.861
CN - Cina 3.800
IT - Italia 3.704
VN - Vietnam 2.829
GB - Regno Unito 2.265
DE - Germania 1.329
HK - Hong Kong 1.293
IN - India 828
SE - Svezia 827
BR - Brasile 744
FR - Francia 727
UA - Ucraina 633
RU - Federazione Russa 606
CI - Costa d'Avorio 363
KR - Corea 342
IE - Irlanda 329
JP - Giappone 315
NL - Olanda 299
BD - Bangladesh 297
ZA - Sudafrica 218
TG - Togo 184
ES - Italia 175
CA - Canada 171
HR - Croazia 166
EE - Estonia 164
FI - Finlandia 158
AR - Argentina 111
PK - Pakistan 98
PL - Polonia 98
PH - Filippine 97
BG - Bulgaria 88
SC - Seychelles 85
TR - Turchia 85
ID - Indonesia 80
MX - Messico 74
CH - Svizzera 67
BE - Belgio 65
PT - Portogallo 62
IQ - Iraq 61
GR - Grecia 59
AT - Austria 57
TW - Taiwan 56
TH - Thailandia 55
AU - Australia 54
IR - Iran 49
JO - Giordania 47
CZ - Repubblica Ceca 40
EC - Ecuador 36
MY - Malesia 35
CL - Cile 34
RO - Romania 34
NG - Nigeria 32
SA - Arabia Saudita 31
EU - Europa 30
CO - Colombia 27
DK - Danimarca 24
EG - Egitto 24
UZ - Uzbekistan 21
MA - Marocco 18
PY - Paraguay 17
SI - Slovenia 17
CR - Costa Rica 15
IL - Israele 15
JM - Giamaica 15
TN - Tunisia 15
LB - Libano 14
AE - Emirati Arabi Uniti 13
NO - Norvegia 13
AL - Albania 12
NP - Nepal 12
LT - Lituania 10
DZ - Algeria 9
HN - Honduras 9
KE - Kenya 9
BY - Bielorussia 8
PE - Perù 8
SV - El Salvador 8
KZ - Kazakistan 7
LV - Lettonia 7
TT - Trinidad e Tobago 7
UY - Uruguay 7
VE - Venezuela 7
AZ - Azerbaigian 6
HU - Ungheria 6
MD - Moldavia 6
PR - Porto Rico 6
SN - Senegal 6
DO - Repubblica Dominicana 5
ET - Etiopia 5
GT - Guatemala 5
NZ - Nuova Zelanda 5
A2 - ???statistics.table.value.countryCode.A2??? 4
BO - Bolivia 4
CM - Camerun 4
CU - Cuba 4
KG - Kirghizistan 4
KH - Cambogia 4
OM - Oman 4
AO - Angola 3
Totale 44.417
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Città #
Singapore 2.729
Southend 1.876
Ashburn 1.394
Fairfield 1.282
Hong Kong 1.187
San Jose 957
Chandler 948
Bologna 869
Ho Chi Minh City 662
Santa Clara 647
Woodbridge 640
Houston 631
Wilmington 614
Hefei 581
Ann Arbor 570
Hanoi 563
Seattle 555
Princeton 488
Cambridge 487
Beijing 472
Council Bluffs 436
Jacksonville 418
Abidjan 363
Boardman 354
Dublin 329
Los Angeles 309
Milan 307
Lauterbourg 277
Dong Ket 250
Seoul 248
Tokyo 240
Nanjing 201
Westminster 201
Dallas 193
Padova 186
New York 185
Lomé 184
Berlin 179
Buffalo 154
Helsinki 125
Jinan 124
Turin 105
Rome 102
Saint Petersburg 102
Guangzhou 98
São Paulo 97
Medford 93
Shenyang 91
Da Nang 89
Florence 89
Nanchang 86
Bengaluru 85
Frankfurt am Main 85
San Diego 85
Redmond 83
Shanghai 83
Chicago 82
Changsha 81
Mülheim 81
Haiphong 80
Sofia 76
Redondo Beach 74
Dearborn 73
Hebei 71
Des Moines 67
Redwood City 66
Munich 64
Phoenix 63
Stockholm 62
Tianjin 57
Falls Church 56
Zhengzhou 54
London 51
Mahé 51
Hangzhou 50
Madrid 50
Hyderabad 49
Amman 46
Brussels 46
Johannesburg 45
Nuremberg 43
Amsterdam 42
Rimini 42
Jiaxing 41
Yubileyny 41
Brooklyn 38
San Francisco 38
Shenzhen 38
Jakarta 37
Naples 36
Toronto 36
Verona 36
Warsaw 36
Barcelona 35
Montreal 35
Sydney 35
Bremen 34
Cesena 33
Modena 33
Atlanta 32
Totale 27.024
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Nome #
A small molecule targeting the multifactorial nature of Alzheimer's disease 537
3,4-Dihydro-1,3,5-triazin-2(1H)-ones as the First Dual BACE-1/GSK-3β Fragment Hits against Alzheimer's Disease 442
A Focused Library of Psychotropic Analogues with Neuroprotective and Neuroregenerative Potential 440
Design and synthesis of small molecules targeting pre-miRNA21 toward the development of ribonuclease targeting chimeras (RIBOTACs) to regulate the oncogenic miRNA21 391
PROTAC-Induced Glycogen Synthase Kinase 3β Degradation as a Potential Therapeutic Strategy for Alzheimer’s Disease 345
2-Phenoxy-1,4-naphthoquinones: From a Multitarget Antitrypanosomal to a Potential Antitumor Profile 331
Targeted Protein Degradation for Infectious Diseases: from Basic Biology to Drug Discovery 313
Fragment Merging, Growing, and Linking Identify New Trypanothione Reductase Inhibitors for Leishmaniasis 312
Enriching Proteolysis Targeting Chimeras with a Second Modality: When Two Are Better Than One 309
Bis(7)-tacrine Derivatives as Multitarget-Directed Ligands: Focus on Anticholinesterase and Antiamyloid Activities 300
Changing paradigm to target microglia in neurodegenerative diseases: from anti-inflammatory strategy to active immunomodulation. 282
Quinolinetrione-tacrine hybrids as multi-target-directed ligands against Alzheimer's disease 281
Discovery of Dual Aβ/Tau Inhibitors and Evaluation of Their Therapeutic Effect on a Drosophila Model of Alzheimer's Disease 279
Molecular hybridization as a tool for designing multitarget drug candidates for complex diseases 267
Sustainable Drug Discovery of Multi-Target-Directed Ligands for Alzheimer's Disease 266
Tau-Centric Multitarget Approach for Alzheimer's Disease: Development of First-in-Class Dual Glycogen Synthase Kinase 3β and Tau-Aggregation Inhibitors 262
A small chemical library of 2-aminoimidazole derivatives as BACE-1 inhibitors: structure-based design, synthesis, and biological evaluation 261
Integrating a quinone substructure into histone deacetylase inhibitors to cope with Alzheimer's disease and cancer 251
Novel Sustainable-by-Design HDAC Inhibitors for the Treatment of Alzheimer's Disease 248
A NEW EPIDERMAL GROWTH FACTOR RECEPTOR INHIBITOR IN COLON CANCER CELLS 246
Design and in vitro study of a dual drug-loaded delivery system produced by electrospinning for the treatment of acute injuries of the central nervous system 244
PROTAC-INDUCED GLYCOGEN SYNTHASE KINASE 3B DEGRADATION 243
Targeting RNA degradation with small molecules: design and synthesis of selective RNA binders and development of ribonuclease targeting chimeras (RIBOTACs) 243
Sustainable production of pharmaceutical, nutraceutical and bioactive compounds from biomass and waste 242
Bifunctional carbazole derivatives for simultaneous therapy and fluorescence imaging in prion disease murine cell models 241
Novel tacrine-tryptophan hybrids: Multi-target directed ligands as potential treatment for Alzheimer's disease 241
Targeting Lewy body dementia with neflamapimod-rasagiline hybrids 240
Progettazione e sintesi di analoghi rigidi di metoctramina nello studio dei recettori muscarinici 240
From combinations to multitarget-directed ligands: A continuum in Alzheimer's disease polypharmacology 240
N-1,2,3-triazole-isatin derivatives for cholinesterase and β-amyloid aggregation inhibition: A comprehensive bioassay study 237
Harnessing the 12 Green Chemistry Principles for Sustainable Antiparasitic Drugs: Toward the One Health Approach 236
Nutritional and Pharmacological Strategies to Regulate Microglial Polarization in Cognitive Aging and Alzheimer's Disease. 232
Progettazione e sintesi di poliammine a potenziale attività antitumorale 231
Electrospun fibers for a local release of an anti-inflammatory and a promyelinating drug 228
α-linolenic acid-valproic acid conjugates: Toward single-molecule polypharmacology for multiple sclerosis 227
Discovery of Sustainable Drugs for Neglected Tropical Diseases: Cashew Nut Shell Liquid (CNSL)-Based Hybrids Target Mitochondrial Function and ATP Production in Trypanosoma brucei 224
Capitolo 2. Proprietà chimico-fisiche e attività biologica 222
Click Chemistry and Targeted Degradation: A Winning Combination for Medicinal Chemists? 221
A new EGFR inhibitor induces apoptosis in colon cancer cells. 221
Rational Approach to discover multipotent anti-Alzheimer drugs 220
Accelerating Drug Discovery Efforts for Trypanosomatidic Infections Using an Integrated Transnational Academic Drug Discovery Platform 220
Turning Donepezil into a Multi-Target-Directed Ligand through a Merging Strategy 220
STUDY OF THE ANTI-INFLAMMATORY ACTIVITY OF NOVEL TACRINE DERIVATIVES WITH LIPIDS EXTRACTED FROM CASHEW NUT SHELL LIQUID 216
Novel multifunctional tacrine–donepezil hybrids against Alzheimer's disease: Design synthesis and bioactivity studies 215
Journal of Medicinal Chemistry 213
Polyamine conjugation of curcumin analogues toward the discovery of mitochondria-directed neuroprotective agents. 210
Curcumin analogs as multi-target antioxidants: focus on mitochondria. 210
Cystamine-tacrine dimer: A new multi-target-directed ligand as potential therapeutic agent for Alzheimer's disease treatment. 210
Development of a Focused Library of Triazole-Linked Privileged-Structure-Based Conjugates Leading to the Discovery of Novel Phenotypic Hits against Protozoan Parasitic Infections 210
Design, synthesis, and biological evaluation of conformationally restricted rivastigmine analogues 209
Progettazione e sintesi di derivati poliamminici per il trattamento della malattia di Alzheimer 205
Multitarget Drug Design Strategy: Quinone–Tacrine Hybrids Designed To Block Amyloid-β Aggregation and To Exert Anticholinesterase and Antioxidant Effects 204
Discovery of sustainable drugs for Alzheimer's disease: cardanol-derived cholinesterase inhibitors with antioxidant and anti-amyloid properties 203
New tacrine dimers with antioxidant linkers as dual drugs: Anti-Alzheimer's and antiproliferative agents 201
Phenothiazine-Tacrine Heterodimers: Pursuing Multitarget Directed Approach in Alzheimer's Disease 201
Alzheimer's disease: new approaches to drug discovery. 200
Riluzole-Rasagiline Hybrids: Toward the Development of Multi-Target-Directed Ligands for Amyotrophic Lateral Sclerosis 199
Targeting Tau Protein with Proximity Inducing Modulators: A New Frontier to Combat Tauopathies 197
Multitargeted drugs discovery: Balancing anti-amyloid and anticholinesterase capacity in a single chemical entity 195
A NEW EPIDERMAL GROWTH FACTOR RECEPTOR INHIBITOR IN COLON CANCER CELLS 195
BACE-1 Inhibitors: From Recent Single-Target Molecules to Multitarget Compounds for Alzheimer's Disease 194
Novel multi target-directed ligands targeting 5-HT4 receptors with in cellulo antioxidant properties as promising leads in Alzheimer's disease 192
Complementary medicinal chemistry-driven strategies toward new antitrypanosomal and antileishmanial lead drug candidates 190
Structure-activity relationships of memoquin: Influence of the chain chirality in the multi-target mechanism of action 187
Design, synthesis and pharmacological evaluation of multitarget GPR40 agonists/HDAC6 inhibitors for Alzheimer's disease 184
Bivalent tacrine-based acetylcholinesterase inhibitors: role of the spacer in the recognition process of the enzyme gorge 180
Parallel Synthesis, Evaluation, and Preliminary Structure-Activity Relationship of 2,5-Diamino-1,4-benzoquinones as a Novel Class of Bivalent Anti-Prion Compound. 179
Cashew nut shell liquid (Cnsl) as a source of drugs for alzheimer’s disease 179
Process for preparation of 1,4-benzoquinone-2,5-diamines by reaction of amines with 1,4-benzoquinones bearing leaving groups at the 2- and 5-positions 178
Toward a rational design of multitarget-directed antioxidants: merging memoquin and lipoic acid molecular frameworks 177
Novel bis(7)-tacrine derivatives as multitarget ligands: focus on anti-cholinesterase and anti-amyloid activities 177
A Fluorescent Styrylquinoline with Combined Therapeutic and Diagnostic Activities against Alzheimer's and Prion Diseases 177
Medicinal Chemistry of Hybrids for Neurodegenerative Diseases 177
From combinations to single-molecule polypharmacology—cromolyn-ibuprofen conjugates for alzheimer’s disease 177
Multi-Target-Directed Drug Design Strategy: From a Dual Binding Site Acetylcholinesterase Inhibitor to a Trifunctional Compound against Alzheimer's Disease 176
Design, synthesis, and biological evaluation of pirenzepine analogs bearing a 1,2-cyclohexanediamine and a perhydroquinoxaline units in exchange for the piperazine ring as antimuscarinics 172
The concept of privileged structures in rational drug design: Focus on acridine and quinoline scaffolds in neurodegenerative and protozoan diseases 172
Benign-by-Design SAHA Analogues for Human and Animal Vector-Borne Parasitic Diseases 171
Hybrid Lipoic Acid Derivatives to Attack Prion Disease on Multiple Fronts 171
Innovative Non-PrP-Targeted Drug Strategy Designed to Enhance Prion Clearance 170
Multitarget Ligands in the Search for Novel Lead Candidates against Trypanosoma and Leishmania 169
Tacripyrimidines, the first tacrine-dihydropyrimidine hybrids, as multi-target-directed ligands for Alzheimer's disease 169
A General Protocol for the Solvent- and Catalyst-Free Synthesis of 2-Styrylquinolines under Focused Microwave Irradiation 168
Navigating the Chemical Space of Multitarget-Directed Ligands: From Hybrids to Fragments in Alzheimer's Disease 167
Multitarget-directed ligands: Innovative chemical probes and therapeutic tools against Alzheimer's disease 167
Surfactant-enriched liposomes to enhance azithromycin efficacy in Chlamydia trachomatis infections 167
Inhibition of Acetylcholinesterase, Beta-Amyloid Aggregation, and NMDA Receptors in Alzheimer's Disease: A Promising Direction for the Multi-target-Directed Ligands Gold Rush 166
Quinones bearing non-steroidal anti-inflammatory fragments as multitarget ligands for Alzheimer’s disease 166
Editorial: Multi-target-directed ligands (MTDL) as challenging research tools in drug discovery: From design to pharmacological evaluation 166
Conjugation of Quinones with Natural Polyamines: Toward an Expanded Antitrypanosomatid Profile 165
Multitarget Drug Discovery and Polypharmacology 163
Novel Class of Quinone-Bearing Polyamines as Multi-Target-Directed Ligands To Combat Alzheimer's Disease 163
From virtual screening hits targeting a cryptic pocket in BACE-1 to a nontoxic brain permeable multitarget anti-Alzheimer lead with disease-modifying and cognition-enhancing effects 163
Privileged structure-guided synthesis of quinazoline derivatives as inhibitors of trypanothione reductase 162
Medicinal Chemistry: A Key Driver in Achieving the Global Sustainable Development Goals 162
A perspective on multi-target drug discovery and design for complex diseases 161
Lipocrine, a multipotent drug for the investigation of Alzheimer's disease 160
Characterization of Cholinesterase inhibitors by means of immobilized enzyme reactor 159
Mitochondria-directed antioxidants in Alzheimer's disease. 159
Synthesis of Monomeric Derivatives To Probe Memoquin's Bivalent Interactions 159
Totale 22.030
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Categoria #
all - tutte 126.055
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 350
Totale 126.405
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20223.933 0 134 255 271 448 336 134 295 221 291 795 753
2022/20234.708 467 668 270 526 330 330 200 347 702 150 449 269
2023/20241.976 129 243 156 173 166 290 117 136 98 174 164 130
2024/20256.407 387 905 660 389 1.022 341 385 247 205 371 350 1.145
2025/202615.430 1.037 1.440 1.374 1.188 1.628 920 1.978 616 2.848 936 877 588
2026/20271.001 439 562 0 0 0 0 0 0 0 0 0 0
Totale 45.271