CRIS Current Research Information System

BOLOGNESI, MARIA LAURA
 Distribuzione geografica
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Continente #
NA - Nord America 15.273
AS - Asia 14.320
EU - Europa 11.975
AF - Africa 986
SA - Sud America 973
OC - Oceania 60
Continente sconosciuto - Info sul continente non disponibili 36
Totale 43.623
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Nazione #
US - Stati Uniti d'America 15.021
SG - Singapore 3.841
CN - Cina 3.800
IT - Italia 3.585
VN - Vietnam 2.842
GB - Regno Unito 2.282
DE - Germania 1.332
HK - Hong Kong 1.283
SE - Svezia 829
IN - India 824
BR - Brasile 734
FR - Francia 728
UA - Ucraina 643
RU - Federazione Russa 610
CI - Costa d'Avorio 365
KR - Corea 341
IE - Irlanda 330
JP - Giappone 316
NL - Olanda 293
BD - Bangladesh 270
ZA - Sudafrica 221
TG - Togo 184
ES - Italia 171
EE - Estonia 165
HR - Croazia 162
FI - Finlandia 158
CA - Canada 144
AR - Argentina 105
PL - Polonia 98
PH - Filippine 95
PK - Pakistan 89
BG - Bulgaria 88
TR - Turchia 85
ID - Indonesia 79
SC - Seychelles 78
MX - Messico 68
CH - Svizzera 66
BE - Belgio 63
PT - Portogallo 62
IQ - Iraq 61
GR - Grecia 59
AT - Austria 57
TW - Taiwan 57
TH - Thailandia 55
AU - Australia 54
IR - Iran 49
JO - Giordania 47
CZ - Repubblica Ceca 39
EC - Ecuador 35
MY - Malesia 35
RO - Romania 34
NG - Nigeria 32
CL - Cile 31
SA - Arabia Saudita 31
EU - Europa 30
CO - Colombia 25
DK - Danimarca 24
EG - Egitto 24
UZ - Uzbekistan 22
MA - Marocco 18
PY - Paraguay 17
SI - Slovenia 17
TN - Tunisia 16
IL - Israele 15
LB - Libano 14
AE - Emirati Arabi Uniti 13
NO - Norvegia 13
AL - Albania 12
NP - Nepal 12
LT - Lituania 10
KE - Kenya 9
BY - Bielorussia 8
DZ - Algeria 8
PE - Perù 8
JM - Giamaica 7
KZ - Kazakistan 7
LV - Lettonia 7
UY - Uruguay 7
VE - Venezuela 7
AZ - Azerbaigian 6
HN - Honduras 6
SN - Senegal 6
DO - Repubblica Dominicana 5
ET - Etiopia 5
HU - Ungheria 5
MD - Moldavia 5
NZ - Nuova Zelanda 5
A2 - ???statistics.table.value.countryCode.A2??? 4
BO - Bolivia 4
CM - Camerun 4
CR - Costa Rica 4
CU - Cuba 4
KG - Kirghizistan 4
KH - Cambogia 4
OM - Oman 4
AO - Angola 3
BA - Bosnia-Erzegovina 3
GH - Ghana 3
GT - Guatemala 3
MM - Myanmar 3
Totale 43.566
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Città #
Singapore 2.708
Southend 1.892
Ashburn 1.366
Fairfield 1.283
Hong Kong 1.179
Chandler 952
San Jose 920
Bologna 856
Ho Chi Minh City 668
Woodbridge 639
Houston 627
Santa Clara 626
Wilmington 618
Hefei 581
Ann Arbor 571
Hanoi 566
Seattle 555
Princeton 493
Cambridge 486
Beijing 462
Jacksonville 423
Abidjan 365
Boardman 355
Dublin 330
Los Angeles 305
Milan 294
Lauterbourg 279
Dong Ket 250
Seoul 247
Tokyo 241
Council Bluffs 227
Nanjing 203
Westminster 203
Padova 188
Dallas 184
Lomé 184
Berlin 181
New York 175
Buffalo 152
Helsinki 125
Jinan 125
Turin 105
Saint Petersburg 103
Guangzhou 98
São Paulo 97
Medford 95
Shenyang 92
Da Nang 90
Nanchang 87
Rome 86
Frankfurt am Main 85
San Diego 84
Shanghai 84
Changsha 83
Florence 83
Mülheim 83
Redmond 83
Bengaluru 81
Haiphong 80
Chicago 76
Sofia 76
Redondo Beach 74
Dearborn 71
Hebei 71
Des Moines 68
Redwood City 66
Munich 64
Stockholm 62
Tianjin 58
Falls Church 56
Phoenix 54
Zhengzhou 54
Mahé 52
Hangzhou 50
London 50
Madrid 50
Hyderabad 49
Amman 46
Brussels 46
Johannesburg 45
Nuremberg 43
Amsterdam 42
Yubileyny 42
Jiaxing 41
Rimini 39
Shenzhen 38
Jakarta 37
Toronto 36
Verona 36
Warsaw 36
Barcelona 35
Sydney 35
Bremen 34
Brooklyn 33
Modena 33
Montreal 33
San Francisco 33
Cesena 32
Naples 32
Olalla 30
Totale 26.641
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Nome #
A small molecule targeting the multifactorial nature of Alzheimer's disease 533
A Focused Library of Psychotropic Analogues with Neuroprotective and Neuroregenerative Potential 440
3,4-Dihydro-1,3,5-triazin-2(1H)-ones as the First Dual BACE-1/GSK-3β Fragment Hits against Alzheimer's Disease 431
Design and synthesis of small molecules targeting pre-miRNA21 toward the development of ribonuclease targeting chimeras (RIBOTACs) to regulate the oncogenic miRNA21 370
PROTAC-Induced Glycogen Synthase Kinase 3β Degradation as a Potential Therapeutic Strategy for Alzheimer’s Disease 338
2-Phenoxy-1,4-naphthoquinones: From a Multitarget Antitrypanosomal to a Potential Antitumor Profile 318
Fragment Merging, Growing, and Linking Identify New Trypanothione Reductase Inhibitors for Leishmaniasis 309
Targeted Protein Degradation for Infectious Diseases: from Basic Biology to Drug Discovery 307
Enriching Proteolysis Targeting Chimeras with a Second Modality: When Two Are Better Than One 304
Bis(7)-tacrine Derivatives as Multitarget-Directed Ligands: Focus on Anticholinesterase and Antiamyloid Activities 297
Changing paradigm to target microglia in neurodegenerative diseases: from anti-inflammatory strategy to active immunomodulation. 280
Quinolinetrione-tacrine hybrids as multi-target-directed ligands against Alzheimer's disease 277
Discovery of Dual Aβ/Tau Inhibitors and Evaluation of Their Therapeutic Effect on a Drosophila Model of Alzheimer's Disease 277
Sustainable Drug Discovery of Multi-Target-Directed Ligands for Alzheimer's Disease 263
A small chemical library of 2-aminoimidazole derivatives as BACE-1 inhibitors: structure-based design, synthesis, and biological evaluation 260
Tau-Centric Multitarget Approach for Alzheimer's Disease: Development of First-in-Class Dual Glycogen Synthase Kinase 3β and Tau-Aggregation Inhibitors 259
Molecular hybridization as a tool for designing multitarget drug candidates for complex diseases 254
Integrating a quinone substructure into histone deacetylase inhibitors to cope with Alzheimer's disease and cancer 247
Novel Sustainable-by-Design HDAC Inhibitors for the Treatment of Alzheimer's Disease 244
Design and in vitro study of a dual drug-loaded delivery system produced by electrospinning for the treatment of acute injuries of the central nervous system 241
Progettazione e sintesi di analoghi rigidi di metoctramina nello studio dei recettori muscarinici 239
A NEW EPIDERMAL GROWTH FACTOR RECEPTOR INHIBITOR IN COLON CANCER CELLS 239
Bifunctional carbazole derivatives for simultaneous therapy and fluorescence imaging in prion disease murine cell models 238
PROTAC-INDUCED GLYCOGEN SYNTHASE KINASE 3B DEGRADATION 237
Targeting Lewy body dementia with neflamapimod-rasagiline hybrids 236
Novel tacrine-tryptophan hybrids: Multi-target directed ligands as potential treatment for Alzheimer's disease 236
From combinations to multitarget-directed ligands: A continuum in Alzheimer's disease polypharmacology 236
N-1,2,3-triazole-isatin derivatives for cholinesterase and β-amyloid aggregation inhibition: A comprehensive bioassay study 233
Harnessing the 12 Green Chemistry Principles for Sustainable Antiparasitic Drugs: Toward the One Health Approach 232
Nutritional and Pharmacological Strategies to Regulate Microglial Polarization in Cognitive Aging and Alzheimer's Disease. 229
Progettazione e sintesi di poliammine a potenziale attività antitumorale 228
Sustainable production of pharmaceutical, nutraceutical and bioactive compounds from biomass and waste 225
α-linolenic acid-valproic acid conjugates: Toward single-molecule polypharmacology for multiple sclerosis 224
Electrospun fibers for a local release of an anti-inflammatory and a promyelinating drug 222
Discovery of Sustainable Drugs for Neglected Tropical Diseases: Cashew Nut Shell Liquid (CNSL)-Based Hybrids Target Mitochondrial Function and ATP Production in Trypanosoma brucei 222
A new EGFR inhibitor induces apoptosis in colon cancer cells. 218
Targeting RNA degradation with small molecules: design and synthesis of selective RNA binders and development of ribonuclease targeting chimeras (RIBOTACs) 217
Rational Approach to discover multipotent anti-Alzheimer drugs 217
Capitolo 2. Proprietà chimico-fisiche e attività biologica 217
Click Chemistry and Targeted Degradation: A Winning Combination for Medicinal Chemists? 216
Accelerating Drug Discovery Efforts for Trypanosomatidic Infections Using an Integrated Transnational Academic Drug Discovery Platform 215
Turning Donepezil into a Multi-Target-Directed Ligand through a Merging Strategy 215
STUDY OF THE ANTI-INFLAMMATORY ACTIVITY OF NOVEL TACRINE DERIVATIVES WITH LIPIDS EXTRACTED FROM CASHEW NUT SHELL LIQUID 212
Journal of Medicinal Chemistry 210
Polyamine conjugation of curcumin analogues toward the discovery of mitochondria-directed neuroprotective agents. 208
Curcumin analogs as multi-target antioxidants: focus on mitochondria. 208
Development of a Focused Library of Triazole-Linked Privileged-Structure-Based Conjugates Leading to the Discovery of Novel Phenotypic Hits against Protozoan Parasitic Infections 207
Design, synthesis, and biological evaluation of conformationally restricted rivastigmine analogues 206
Cystamine-tacrine dimer: A new multi-target-directed ligand as potential therapeutic agent for Alzheimer's disease treatment. 206
Novel multifunctional tacrine–donepezil hybrids against Alzheimer's disease: Design synthesis and bioactivity studies 206
Progettazione e sintesi di derivati poliamminici per il trattamento della malattia di Alzheimer 202
Multitarget Drug Design Strategy: Quinone–Tacrine Hybrids Designed To Block Amyloid-β Aggregation and To Exert Anticholinesterase and Antioxidant Effects 202
Discovery of sustainable drugs for Alzheimer's disease: cardanol-derived cholinesterase inhibitors with antioxidant and anti-amyloid properties 200
Alzheimer's disease: new approaches to drug discovery. 198
New tacrine dimers with antioxidant linkers as dual drugs: Anti-Alzheimer's and antiproliferative agents 197
Riluzole-Rasagiline Hybrids: Toward the Development of Multi-Target-Directed Ligands for Amyotrophic Lateral Sclerosis 196
Multitargeted drugs discovery: Balancing anti-amyloid and anticholinesterase capacity in a single chemical entity 194
Phenothiazine-Tacrine Heterodimers: Pursuing Multitarget Directed Approach in Alzheimer's Disease 194
BACE-1 Inhibitors: From Recent Single-Target Molecules to Multitarget Compounds for Alzheimer's Disease 192
Complementary medicinal chemistry-driven strategies toward new antitrypanosomal and antileishmanial lead drug candidates 190
A NEW EPIDERMAL GROWTH FACTOR RECEPTOR INHIBITOR IN COLON CANCER CELLS 190
Novel multi target-directed ligands targeting 5-HT4 receptors with in cellulo antioxidant properties as promising leads in Alzheimer's disease 190
Targeting Tau Protein with Proximity Inducing Modulators: A New Frontier to Combat Tauopathies 187
Structure-activity relationships of memoquin: Influence of the chain chirality in the multi-target mechanism of action 183
Toward a rational design of multitarget-directed antioxidants: merging memoquin and lipoic acid molecular frameworks 177
Bivalent tacrine-based acetylcholinesterase inhibitors: role of the spacer in the recognition process of the enzyme gorge 176
Multi-Target-Directed Drug Design Strategy: From a Dual Binding Site Acetylcholinesterase Inhibitor to a Trifunctional Compound against Alzheimer's Disease 176
Novel bis(7)-tacrine derivatives as multitarget ligands: focus on anti-cholinesterase and anti-amyloid activities 176
A Fluorescent Styrylquinoline with Combined Therapeutic and Diagnostic Activities against Alzheimer's and Prion Diseases 176
Process for preparation of 1,4-benzoquinone-2,5-diamines by reaction of amines with 1,4-benzoquinones bearing leaving groups at the 2- and 5-positions 175
Parallel Synthesis, Evaluation, and Preliminary Structure-Activity Relationship of 2,5-Diamino-1,4-benzoquinones as a Novel Class of Bivalent Anti-Prion Compound. 175
Medicinal Chemistry of Hybrids for Neurodegenerative Diseases 175
From combinations to single-molecule polypharmacology—cromolyn-ibuprofen conjugates for alzheimer’s disease 175
The concept of privileged structures in rational drug design: Focus on acridine and quinoline scaffolds in neurodegenerative and protozoan diseases 171
Cashew nut shell liquid (Cnsl) as a source of drugs for alzheimer’s disease 171
Design, synthesis, and biological evaluation of pirenzepine analogs bearing a 1,2-cyclohexanediamine and a perhydroquinoxaline units in exchange for the piperazine ring as antimuscarinics 170
Design, synthesis and pharmacological evaluation of multitarget GPR40 agonists/HDAC6 inhibitors for Alzheimer's disease 169
Multitarget Ligands in the Search for Novel Lead Candidates against Trypanosoma and Leishmania 167
Hybrid Lipoic Acid Derivatives to Attack Prion Disease on Multiple Fronts 167
Tacripyrimidines, the first tacrine-dihydropyrimidine hybrids, as multi-target-directed ligands for Alzheimer's disease 167
Multitarget-directed ligands: Innovative chemical probes and therapeutic tools against Alzheimer's disease 166
A General Protocol for the Solvent- and Catalyst-Free Synthesis of 2-Styrylquinolines under Focused Microwave Irradiation 165
Editorial: Multi-target-directed ligands (MTDL) as challenging research tools in drug discovery: From design to pharmacological evaluation 165
Quinones bearing non-steroidal anti-inflammatory fragments as multitarget ligands for Alzheimer’s disease 164
Navigating the Chemical Space of Multitarget-Directed Ligands: From Hybrids to Fragments in Alzheimer's Disease 164
Inhibition of Acetylcholinesterase, Beta-Amyloid Aggregation, and NMDA Receptors in Alzheimer's Disease: A Promising Direction for the Multi-target-Directed Ligands Gold Rush 163
Conjugation of Quinones with Natural Polyamines: Toward an Expanded Antitrypanosomatid Profile 163
Multitarget Drug Discovery and Polypharmacology 162
Novel Class of Quinone-Bearing Polyamines as Multi-Target-Directed Ligands To Combat Alzheimer's Disease 161
Benign-by-Design SAHA Analogues for Human and Animal Vector-Borne Parasitic Diseases 160
Privileged structure-guided synthesis of quinazoline derivatives as inhibitors of trypanothione reductase 160
Lipocrine, a multipotent drug for the investigation of Alzheimer's disease 159
Synthesis of Monomeric Derivatives To Probe Memoquin's Bivalent Interactions 159
From virtual screening hits targeting a cryptic pocket in BACE-1 to a nontoxic brain permeable multitarget anti-Alzheimer lead with disease-modifying and cognition-enhancing effects 159
A perspective on multi-target drug discovery and design for complex diseases 158
Analysis of the muscarinic receptor subtype mediating inhibition of the neurogenic contractions in rabbit isolated vas deferens by a series of polymethylene tetra-amines 157
Investigation of the photostability properties of memoquin, a quinone derivative for the treatment of Alzheimer's disease. 157
Mitochondria-directed antioxidants in Alzheimer's disease. 157
Progress in acetylcholinesterase inhibitors for Alzheimer's disease: an update 157
Exploiting the lipoic acid structure in the search for novel multitarget ligands against Alzheimer's disease. 157
Totale 21.594
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Categoria #
all - tutte 121.302
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 333
Totale 121.635
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021678 0 0 0 0 0 0 0 0 0 0 0 678
2021/20224.476 519 137 255 273 451 337 134 296 223 294 798 759
2022/20234.733 470 671 272 528 332 331 200 348 703 151 457 270
2023/20241.988 130 243 156 174 166 297 117 136 98 174 164 133
2024/20256.434 388 908 663 390 1.028 344 387 247 206 372 351 1.150
2025/202615.418 1.038 1.446 1.382 1.192 1.636 924 1.982 616 2.872 938 880 512
Totale 44.409