CRIS Current Research Information System

BOLOGNESI, MARIA LAURA
 Distribuzione geografica
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Continente #
NA - Nord America 12.831
EU - Europa 10.849
AS - Asia 9.916
AF - Africa 874
SA - Sud America 807
OC - Oceania 50
Continente sconosciuto - Info sul continente non disponibili 36
Totale 35.363
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Nazione #
US - Stati Uniti d'America 12.693
CN - Cina 3.178
IT - Italia 3.106
SG - Singapore 3.087
GB - Regno Unito 2.234
DE - Germania 1.272
VN - Vietnam 1.162
HK - Hong Kong 833
SE - Svezia 822
IN - India 712
UA - Ucraina 634
BR - Brasile 624
RU - Federazione Russa 602
FR - Francia 434
CI - Costa d'Avorio 363
IE - Irlanda 324
KR - Corea 303
NL - Olanda 261
JP - Giappone 192
TG - Togo 183
ZA - Sudafrica 183
EE - Estonia 165
ES - Italia 149
HR - Croazia 147
FI - Finlandia 99
AR - Argentina 86
BG - Bulgaria 85
CA - Canada 80
PL - Polonia 80
SC - Seychelles 77
ID - Indonesia 64
CH - Svizzera 63
PT - Portogallo 60
TR - Turchia 59
GR - Grecia 58
BE - Belgio 54
PK - Pakistan 51
IR - Iran 49
AT - Austria 48
AU - Australia 47
MX - Messico 44
JO - Giordania 40
BD - Bangladesh 35
CZ - Repubblica Ceca 35
EC - Ecuador 32
RO - Romania 32
NG - Nigeria 31
EU - Europa 30
MY - Malesia 24
TW - Taiwan 22
CL - Cile 19
CO - Colombia 18
DK - Danimarca 16
IQ - Iraq 15
SI - Slovenia 15
NO - Norvegia 13
PY - Paraguay 13
IL - Israele 12
LB - Libano 12
PH - Filippine 10
UZ - Uzbekistan 10
TH - Thailandia 9
AE - Emirati Arabi Uniti 8
EG - Egitto 8
NP - Nepal 8
AL - Albania 6
LT - Lituania 6
LV - Lettonia 6
MA - Marocco 6
PE - Perù 6
SA - Arabia Saudita 6
DZ - Algeria 5
A2 - ???statistics.table.value.countryCode.A2??? 4
CU - Cuba 4
HU - Ungheria 4
KZ - Kazakistan 4
TN - Tunisia 4
BO - Bolivia 3
CM - Camerun 3
DO - Repubblica Dominicana 3
MD - Moldavia 3
MU - Mauritius 3
SM - San Marino 3
SN - Senegal 3
UY - Uruguay 3
VE - Venezuela 3
AO - Angola 2
BA - Bosnia-Erzegovina 2
BH - Bahrain 2
LI - Liechtenstein 2
LK - Sri Lanka 2
LU - Lussemburgo 2
MK - Macedonia 2
NZ - Nuova Zelanda 2
SK - Slovacchia (Repubblica Slovacca) 2
XK - ???statistics.table.value.countryCode.XK??? 2
AM - Armenia 1
BN - Brunei Darussalam 1
BY - Bielorussia 1
CG - Congo 1
Totale 35.346
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Città #
Singapore 2.033
Southend 1.892
Fairfield 1.283
Ashburn 1.188
Chandler 952
Hong Kong 800
Bologna 738
Woodbridge 639
Houston 621
Wilmington 618
Santa Clara 593
Hefei 575
Ann Arbor 571
Seattle 550
Princeton 493
Cambridge 484
Beijing 422
Jacksonville 418
Abidjan 363
Boardman 341
Dublin 324
Milan 261
Dong Ket 250
Ho Chi Minh City 249
Seoul 245
Westminster 203
Nanjing 201
Los Angeles 188
Padova 188
Lomé 183
Berlin 180
Hanoi 173
Dallas 168
Tokyo 161
Buffalo 139
Jinan 124
New York 112
Turin 104
Saint Petersburg 103
Medford 95
Shenyang 85
Nanchang 84
San Diego 84
Mülheim 83
Redmond 83
Changsha 77
São Paulo 77
Sofia 76
Redondo Beach 74
Bengaluru 72
Dearborn 71
Hebei 71
Helsinki 71
Guangzhou 68
Des Moines 66
Redwood City 66
Rome 65
Munich 61
Shanghai 61
Florence 58
Stockholm 57
Falls Church 56
Chicago 53
Frankfurt am Main 53
Mahé 52
Hyderabad 48
Tianjin 47
Zhengzhou 47
Madrid 44
Brussels 43
Yubileyny 42
London 41
Amman 40
Nuremberg 39
Jiaxing 38
Barcelona 34
Hangzhou 34
Jakarta 34
Verona 34
Bremen 33
Phoenix 33
Cesena 32
Amsterdam 30
Olalla 30
Brooklyn 29
Lisbon 29
Siracusa 29
Taizhou 29
Bern 28
Haikou 28
Sydney 27
Norwalk 26
Kunming 25
Modena 25
Mountain View 24
Portogruaro 24
Vienna 24
Warsaw 24
Ningbo 23
Bari 22
Totale 22.088
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Nome #
A small molecule targeting the multifactorial nature of Alzheimer's disease 465
3,4-Dihydro-1,3,5-triazin-2(1H)-ones as the First Dual BACE-1/GSK-3β Fragment Hits against Alzheimer's Disease 376
A Focused Library of Psychotropic Analogues with Neuroprotective and Neuroregenerative Potential 361
PROTAC-Induced Glycogen Synthase Kinase 3β Degradation as a Potential Therapeutic Strategy for Alzheimer’s Disease 290
Bis(7)-tacrine Derivatives as Multitarget-Directed Ligands: Focus on Anticholinesterase and Antiamyloid Activities 278
Enriching Proteolysis Targeting Chimeras with a Second Modality: When Two Are Better Than One 262
Targeted Protein Degradation for Infectious Diseases: from Basic Biology to Drug Discovery 250
Changing paradigm to target microglia in neurodegenerative diseases: from anti-inflammatory strategy to active immunomodulation. 248
Fragment Merging, Growing, and Linking Identify New Trypanothione Reductase Inhibitors for Leishmaniasis 238
A small chemical library of 2-aminoimidazole derivatives as BACE-1 inhibitors: structure-based design, synthesis, and biological evaluation 238
Design and synthesis of small molecules targeting pre-miRNA21 toward the development of ribonuclease targeting chimeras (RIBOTACs) to regulate the oncogenic miRNA21 235
Quinolinetrione-tacrine hybrids as multi-target-directed ligands against Alzheimer's disease 234
Progettazione e sintesi di analoghi rigidi di metoctramina nello studio dei recettori muscarinici 226
Tau-Centric Multitarget Approach for Alzheimer's Disease: Development of First-in-Class Dual Glycogen Synthase Kinase 3β and Tau-Aggregation Inhibitors 221
Bifunctional carbazole derivatives for simultaneous therapy and fluorescence imaging in prion disease murine cell models 219
Discovery of Dual Aβ/Tau Inhibitors and Evaluation of Their Therapeutic Effect on a Drosophila Model of Alzheimer's Disease 211
2-Phenoxy-1,4-naphthoquinones: From a Multitarget Antitrypanosomal to a Potential Antitumor Profile 206
Sustainable Drug Discovery of Multi-Target-Directed Ligands for Alzheimer's Disease 206
Rational Approach to discover multipotent anti-Alzheimer drugs 204
N-1,2,3-triazole-isatin derivatives for cholinesterase and β-amyloid aggregation inhibition: A comprehensive bioassay study 203
Integrating a quinone substructure into histone deacetylase inhibitors to cope with Alzheimer's disease and cancer 202
Progettazione e sintesi di poliammine a potenziale attività antitumorale 202
A new EGFR inhibitor induces apoptosis in colon cancer cells. 201
Accelerating Drug Discovery Efforts for Trypanosomatidic Infections Using an Integrated Transnational Academic Drug Discovery Platform 201
Discovery of Sustainable Drugs for Neglected Tropical Diseases: Cashew Nut Shell Liquid (CNSL)-Based Hybrids Target Mitochondrial Function and ATP Production in Trypanosoma brucei 199
Novel tacrine-tryptophan hybrids: Multi-target directed ligands as potential treatment for Alzheimer's disease 196
From combinations to multitarget-directed ligands: A continuum in Alzheimer's disease polypharmacology 196
Nutritional and Pharmacological Strategies to Regulate Microglial Polarization in Cognitive Aging and Alzheimer's Disease. 195
Novel Sustainable-by-Design HDAC Inhibitors for the Treatment of Alzheimer's Disease 194
Design and in vitro study of a dual drug-loaded delivery system produced by electrospinning for the treatment of acute injuries of the central nervous system 194
Design, synthesis, and biological evaluation of conformationally restricted rivastigmine analogues 193
Molecular hybridization as a tool for designing multitarget drug candidates for complex diseases 186
Curcumin analogs as multi-target antioxidants: focus on mitochondria. 185
A NEW EPIDERMAL GROWTH FACTOR RECEPTOR INHIBITOR IN COLON CANCER CELLS 183
Development of a Focused Library of Triazole-Linked Privileged-Structure-Based Conjugates Leading to the Discovery of Novel Phenotypic Hits against Protozoan Parasitic Infections 183
α-linolenic acid-valproic acid conjugates: Toward single-molecule polypharmacology for multiple sclerosis 183
Harnessing the 12 Green Chemistry Principles for Sustainable Antiparasitic Drugs: Toward the One Health Approach 182
Alzheimer's disease: new approaches to drug discovery. 182
Capitolo 2. Proprietà chimico-fisiche e attività biologica 180
Polyamine conjugation of curcumin analogues toward the discovery of mitochondria-directed neuroprotective agents. 179
Progettazione e sintesi di derivati poliamminici per il trattamento della malattia di Alzheimer 175
Discovery of sustainable drugs for Alzheimer's disease: cardanol-derived cholinesterase inhibitors with antioxidant and anti-amyloid properties 175
BACE-1 Inhibitors: From Recent Single-Target Molecules to Multitarget Compounds for Alzheimer's Disease 174
Electrospun fibers for a local release of an anti-inflammatory and a promyelinating drug 173
Multitarget Drug Design Strategy: Quinone–Tacrine Hybrids Designed To Block Amyloid-β Aggregation and To Exert Anticholinesterase and Antioxidant Effects 168
Novel multi target-directed ligands targeting 5-HT4 receptors with in cellulo antioxidant properties as promising leads in Alzheimer's disease 168
Journal of Medicinal Chemistry 167
Click Chemistry and Targeted Degradation: A Winning Combination for Medicinal Chemists? 165
Cystamine-tacrine dimer: A new multi-target-directed ligand as potential therapeutic agent for Alzheimer's disease treatment. 165
Sustainable production of pharmaceutical, nutraceutical and bioactive compounds from biomass and waste 165
Multitargeted drugs discovery: Balancing anti-amyloid and anticholinesterase capacity in a single chemical entity 164
A NEW EPIDERMAL GROWTH FACTOR RECEPTOR INHIBITOR IN COLON CANCER CELLS 164
Bivalent tacrine-based acetylcholinesterase inhibitors: role of the spacer in the recognition process of the enzyme gorge 162
Parallel Synthesis, Evaluation, and Preliminary Structure-Activity Relationship of 2,5-Diamino-1,4-benzoquinones as a Novel Class of Bivalent Anti-Prion Compound. 162
A Fluorescent Styrylquinoline with Combined Therapeutic and Diagnostic Activities against Alzheimer's and Prion Diseases 162
Complementary medicinal chemistry-driven strategies toward new antitrypanosomal and antileishmanial lead drug candidates 161
Structure-activity relationships of memoquin: Influence of the chain chirality in the multi-target mechanism of action 159
Turning Donepezil into a Multi-Target-Directed Ligand through a Merging Strategy 156
Phenothiazine-Tacrine Heterodimers: Pursuing Multitarget Directed Approach in Alzheimer's Disease 156
Toward a rational design of multitarget-directed antioxidants: merging memoquin and lipoic acid molecular frameworks 155
Hybrid Lipoic Acid Derivatives to Attack Prion Disease on Multiple Fronts 154
New tacrine dimers with antioxidant linkers as dual drugs: Anti-Alzheimer's and antiproliferative agents 154
Multi-Target-Directed Drug Design Strategy: From a Dual Binding Site Acetylcholinesterase Inhibitor to a Trifunctional Compound against Alzheimer's Disease 153
Design, synthesis, and biological evaluation of pirenzepine analogs bearing a 1,2-cyclohexanediamine and a perhydroquinoxaline units in exchange for the piperazine ring as antimuscarinics 153
A General Protocol for the Solvent- and Catalyst-Free Synthesis of 2-Styrylquinolines under Focused Microwave Irradiation 153
The concept of privileged structures in rational drug design: Focus on acridine and quinoline scaffolds in neurodegenerative and protozoan diseases 153
Novel bis(7)-tacrine derivatives as multitarget ligands: focus on anti-cholinesterase and anti-amyloid activities 152
Medicinal Chemistry of Hybrids for Neurodegenerative Diseases 152
Process for preparation of 1,4-benzoquinone-2,5-diamines by reaction of amines with 1,4-benzoquinones bearing leaving groups at the 2- and 5-positions 148
Tacripyrimidines, the first tacrine-dihydropyrimidine hybrids, as multi-target-directed ligands for Alzheimer's disease 148
Multitargeted drugs for the treatment of Alzheimer's disease 146
Quinones bearing non-steroidal anti-inflammatory fragments as multitarget ligands for Alzheimer’s disease 146
Navigating the Chemical Space of Multitarget-Directed Ligands: From Hybrids to Fragments in Alzheimer's Disease 146
PROTAC-INDUCED GLYCOGEN SYNTHASE KINASE 3B DEGRADATION 144
Conjugation of Quinones with Natural Polyamines: Toward an Expanded Antitrypanosomatid Profile 144
STUDY OF THE ANTI-INFLAMMATORY ACTIVITY OF NOVEL TACRINE DERIVATIVES WITH LIPIDS EXTRACTED FROM CASHEW NUT SHELL LIQUID 144
Cashew nut shell liquid (Cnsl) as a source of drugs for alzheimer’s disease 144
Riluzole-Rasagiline Hybrids: Toward the Development of Multi-Target-Directed Ligands for Amyotrophic Lateral Sclerosis 143
A perspective on multi-target drug discovery and design for complex diseases 143
Investigation of the photostability properties of memoquin, a quinone derivative for the treatment of Alzheimer's disease. 142
Mitochondria-directed antioxidants in Alzheimer's disease. 142
Drug Discovery Strategies for the Generation of Multitarget Ligands against Neglected Tropical Diseases 142
Novel Class of Quinone-Bearing Polyamines as Multi-Target-Directed Ligands To Combat Alzheimer's Disease 141
Multitarget-directed ligands: Innovative chemical probes and therapeutic tools against Alzheimer's disease 141
Targeting Tau Protein with Proximity Inducing Modulators: A New Frontier to Combat Tauopathies 140
Memoquin: a multi-target-directed ligand as an innovative therapeutic opportunity for Alzheimer's disease 140
Design, synthesis, and biological evaluation of substituted 2,3-dihydro-1H-cyclopenta[b]quinolin-9-ylamine related compounds as fructose-1,6-bisphosphatase inhibitors 140
Editorial: Multi-target-directed ligands (MTDL) as challenging research tools in drug discovery: From design to pharmacological evaluation 140
Inhibition of Acetylcholinesterase, Beta-Amyloid Aggregation, and NMDA Receptors in Alzheimer's Disease: A Promising Direction for the Multi-target-Directed Ligands Gold Rush 139
Progress in acetylcholinesterase inhibitors for Alzheimer's disease: an update 139
Lipocrine, a multipotent drug for the investigation of Alzheimer's disease 138
Monolithic stationary phase coupled with coulometric detection: development of an ion-pair HPLC method for the analysis of quinone-bearing compounds. 138
Docking ligands on protein surfaces: the case study of prion protein. 138
Multitarget Drug Discovery and Polypharmacology 138
Memoquin: a new compound to attack Alzheimer's disease drug discovery 137
Characterization of Cholinesterase inhibitors by means of immobilized enzyme reactor 137
Privileged structure-guided synthesis of quinazoline derivatives as inhibitors of trypanothione reductase 137
Multitarget Ligands in the Search for Novel Lead Candidates against Trypanosoma and Leishmania 137
Remembering Marie Curie's legacy 137
Tackling neurodegeneration with multi-target and theranostic small molecules 136
Totale 18.022
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Categoria #
all - tutte 102.429
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 273
Totale 102.702
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20212.085 0 0 0 0 0 308 163 243 265 235 193 678
2021/20224.476 519 137 255 273 451 337 134 296 223 294 798 759
2022/20234.733 470 671 272 528 332 331 200 348 703 151 457 270
2023/20241.988 130 243 156 174 166 297 117 136 98 174 164 133
2024/20256.434 388 908 663 390 1.028 344 387 247 206 372 351 1.150
2025/20267.080 1.038 1.446 1.382 1.192 1.636 386 0 0 0 0 0 0
Totale 36.071