CRIS Current Research Information System

ROSINI, MICHELA
 Distribuzione geografica
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Continente #
NA - Nord America 6.404
AS - Asia 5.555
EU - Europa 4.644
AF - Africa 476
SA - Sud America 269
OC - Oceania 5
Totale 17.353
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Nazione #
US - Stati Uniti d'America 6.341
CN - Cina 1.632
SG - Singapore 1.471
VN - Vietnam 1.271
IT - Italia 1.134
GB - Regno Unito 1.041
DE - Germania 518
HK - Hong Kong 429
SE - Svezia 398
UA - Ucraina 303
FR - Francia 298
IN - India 269
RU - Federazione Russa 254
CI - Costa d'Avorio 203
BR - Brasile 181
IE - Irlanda 150
NL - Olanda 125
JP - Giappone 98
TG - Togo 97
ZA - Sudafrica 97
KR - Corea 86
EE - Estonia 78
FI - Finlandia 62
BG - Bulgaria 53
ES - Italia 43
AR - Argentina 40
ID - Indonesia 37
SC - Seychelles 37
CA - Canada 35
BE - Belgio 34
JO - Giordania 34
PH - Filippine 28
HR - Croazia 25
TH - Thailandia 25
CH - Svizzera 24
TW - Taiwan 24
IQ - Iraq 22
TR - Turchia 22
BD - Bangladesh 20
MX - Messico 20
MY - Malesia 18
PK - Pakistan 17
GR - Grecia 16
AT - Austria 14
PL - Polonia 13
CL - Cile 11
EC - Ecuador 11
RO - Romania 11
CZ - Repubblica Ceca 10
IR - Iran 10
SA - Arabia Saudita 10
CO - Colombia 9
LB - Libano 8
UZ - Uzbekistan 8
LU - Lussemburgo 7
LT - Lituania 6
MA - Marocco 6
NG - Nigeria 6
PY - Paraguay 6
EG - Egitto 5
ET - Etiopia 5
PE - Perù 5
PT - Portogallo 5
TN - Tunisia 4
AU - Australia 3
DZ - Algeria 3
IL - Israele 3
KE - Kenya 3
MD - Moldavia 3
SK - Slovacchia (Repubblica Slovacca) 3
AE - Emirati Arabi Uniti 2
AL - Albania 2
BY - Bielorussia 2
CG - Congo 2
CR - Costa Rica 2
KZ - Kazakistan 2
LK - Sri Lanka 2
LV - Lettonia 2
LY - Libia 2
NO - Norvegia 2
NP - Nepal 2
OM - Oman 2
SM - San Marino 2
UY - Uruguay 2
VE - Venezuela 2
AZ - Azerbaigian 1
BA - Bosnia-Erzegovina 1
BO - Bolivia 1
CM - Camerun 1
DK - Danimarca 1
DO - Repubblica Dominicana 1
FK - Isole Falkland (Malvinas) 1
GH - Ghana 1
GT - Guatemala 1
HU - Ungheria 1
IM - Isola di Man 1
JM - Giamaica 1
KW - Kuwait 1
ME - Montenegro 1
MK - Macedonia 1
Totale 17.343
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Città #
Singapore 1.003
Southend 880
Fairfield 612
Ashburn 564
Chandler 449
Hong Kong 409
Santa Clara 382
Ho Chi Minh City 333
San Jose 306
Houston 295
Woodbridge 293
Hanoi 274
Seattle 263
Wilmington 258
Bologna 239
Hefei 224
Princeton 221
Jacksonville 207
Cambridge 206
Abidjan 203
Beijing 200
Ann Arbor 188
Dublin 149
Boardman 140
Dallas 130
Lauterbourg 105
New York 102
Lomé 97
Los Angeles 95
Nanjing 95
Westminster 94
Padova 92
Dong Ket 82
Tokyo 82
Berlin 73
Jinan 69
Seoul 66
Buffalo 62
Saint Petersburg 54
Sofia 53
Milan 52
Haiphong 50
Shenyang 50
Guangzhou 47
Council Bluffs 46
Da Nang 45
Helsinki 44
Medford 43
Changsha 41
Mülheim 39
Nanchang 38
Redwood City 38
Amman 34
Shanghai 34
Tianjin 33
Turin 33
Brussels 31
Hebei 30
Redondo Beach 30
San Diego 29
Munich 27
Rome 27
Frankfurt am Main 26
Mahé 26
Dearborn 22
Florence 22
Jakarta 22
Hangzhou 21
Des Moines 20
Johannesburg 20
Zhengzhou 20
Chicago 19
Falls Church 19
London 19
The Dalles 18
Verona 18
Yubileyny 18
Bengaluru 17
Jiaxing 17
Mountain View 17
São Paulo 17
Biên Hòa 16
Phoenix 16
Siracusa 16
Thái Nguyên 16
Haikou 15
Redmond 15
Barcelona 14
Bari 14
Chengdu 14
Montreal 14
Olalla 14
Wuhan 14
Chennai 13
Istanbul 13
Madrid 13
Orem 13
San Francisco 13
Brooklyn 12
Catania 12
Totale 11.135
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Nome #
Bis(7)-tacrine Derivatives as Multitarget-Directed Ligands: Focus on Anticholinesterase and Antiamyloid Activities 297
Benextramine and derivatives as novel human monoamine oxidases inhibitors: an integrated approach 265
Galantamine-memantine hybrids for Alzheimer's disease: The influence of linker rigidity in biological activity and pharmacokinetic properties 256
Progettazione e sintesi di analoghi rigidi di metoctramina nello studio dei recettori muscarinici 237
Merging memantine and ferulic acid to probe connections between NMDA receptors, oxidative stress and amyloid-β peptide in Alzheimer's disease 223
Reversible human serum albumin binding of lipocrine: a circular dichroism study. 219
Nature-Inspired Multifunctional Ligands: Focusing on Amyloid-Based Molecular Mechanisms of Alzheimer’s Disease 215
Rational Approach to discover multipotent anti-Alzheimer drugs 214
Structure-activity relationships of acetylcholinesterase noncovalent inhibitors based on a polyamine backbone. 3. Effect of replacing the inner polymethylene chain with cyclic moieties 208
Curcumin analogs as multi-target antioxidants: focus on mitochondria. 207
Polyamine conjugation of curcumin analogues toward the discovery of mitochondria-directed neuroprotective agents. 203
Exploring the activity of polyamine analogues on polyamine and spermine oxidase: methoctramine, a potent and selective inhibitor of polyamine oxidase 200
Design, synthesis, and biological evaluation of conformationally restricted rivastigmine analogues 199
Immunomodulators inspired by nature: A review on curcumin and Echinacea 199
Farmaci per le malattie neurodegenerative 195
Design and synthesis of new multitarget agents for the study of neuroinflammation in Alzheimer's disease 195
Progettazione e sintesi di derivati poliamminici per il trattamento della malattia di Alzheimer 193
Alzheimer's disease: new approaches to drug discovery. 193
Structure-activity relationships of novel substituted naphthalene diimides as anticancer agents 193
Multitargeted drugs discovery: Balancing anti-amyloid and anticholinesterase capacity in a single chemical entity 192
Design, synthesis, and biological evaluation of prazosin-related derivatives as multipotent compounds 184
In vivo characterization of ARN14140, a memantine/galantamine-based multi-target compound for Alzheimer's disease 182
Polypharmacology: the rise of multitarget drugs over combination therapies 180
Lights and shadows of electrophile signaling: Focus on the Nrf2-Keap1 pathway 180
Structure-activity relationships of memoquin: Influence of the chain chirality in the multi-target mechanism of action 179
Cystamine-tacrine dimer: A new multi-target-directed ligand as potential therapeutic agent for Alzheimer's disease treatment. 178
Memantine Derivatives as Multitarget Agents in Alzheimer’s Disease 178
Eye-Light on Age-Related Macular Degeneration: Targeting Nrf2-Pathway as a Novel Therapeutic Strategy for Retinal Pigment Epithelium 177
Double Attack to Oxidative Stress in Neurodegenerative Disorders: MAO-B and Nrf2 as Elected Targets 175
Inhibition of β-Amyloid Aggregation in Alzheimer's Disease: The Key Role of (Pro)electrophilic Warheads 173
Novel bis(7)-tacrine derivatives as multitarget ligands: focus on anti-cholinesterase and anti-amyloid activities 173
Bivalent tacrine-based acetylcholinesterase inhibitors: role of the spacer in the recognition process of the enzyme gorge 171
Toward a rational design of multitarget-directed antioxidants: merging memoquin and lipoic acid molecular frameworks 171
Multi-Target-Directed Drug Design Strategy: From a Dual Binding Site Acetylcholinesterase Inhibitor to a Trifunctional Compound against Alzheimer's Disease 169
Polyamine Conjugation as a Promising Strategy To Target Amyloid Aggregation in the Framework of Alzheimer’s Disease 168
Design, synthesis, and biological evaluation of pirenzepine analogs bearing a 1,2-cyclohexanediamine and a perhydroquinoxaline units in exchange for the piperazine ring as antimuscarinics 165
Hybrid Lipoic Acid Derivatives to Attack Prion Disease on Multiple Fronts 165
Exploiting RNA as a new biomolecular target for synthetic polyamines 165
Multitarget-directed ligands: Innovative chemical probes and therapeutic tools against Alzheimer's disease 163
Combining galantamine and memantine in multitargeted, new chemical entities potentially useful in Alzheimer's disease. 161
Inhibition of Acetylcholinesterase, Beta-Amyloid Aggregation, and NMDA Receptors in Alzheimer's Disease: A Promising Direction for the Multi-target-Directed Ligands Gold Rush 160
Dual target compounds for the treatment of Alzheimer’s disease. 159
Novel Class of Quinone-Bearing Polyamines as Multi-Target-Directed Ligands To Combat Alzheimer's Disease 158
Preparation of (hetero)aromatic (hetero)cyclic carboxamides for the treatment of Alzheimer's disease 156
Mitochondria-directed antioxidants in Alzheimer's disease. 156
Progress in acetylcholinesterase inhibitors for Alzheimer's disease: an update 155
Design, synthesis, and biological evaluation of substituted 2,3-dihydro-1H-cyclopenta[b]quinolin-9-ylamine related compounds as fructose-1,6-bisphosphatase inhibitors 154
Synthesis of Monomeric Derivatives To Probe Memoquin's Bivalent Interactions 154
Exploiting the lipoic acid structure in the search for novel multitarget ligands against Alzheimer's disease. 154
Analysis of the muscarinic receptor subtype mediating inhibition of the neurogenic contractions in rabbit isolated vas deferens by a series of polymethylene tetra-amines 153
An optimized polyamine moiety boosts the potency of human type II topoisomerase poisons as quantified by comparative analysis centered on the clinical candidate F14512 153
Multifunctional Tacrine Derivatives in Alzheimer’s Disease 152
Multi-target Design Strategies in the Context of Alzheimer's Disease: Acetylcholinesterase Inhibition and NMDA Receptor Antagonism as the Driving Forces 152
Lipocrine, a multipotent drug for the investigation of Alzheimer's disease 151
Oxidative stress in Alzheimer’s disease: are we connecting the dots? 150
New quinazoline compounds as non-peptidomimetic BACE-1 inhibitors in the treatment of Alzheimer's disease 149
Polyamine–Drug Conjugates: Do They Boost Drug Activity? 148
Modulation of Keap1/Nrf2/ARE signaling pathway by curcuma- And garlic-derived hybrids 148
One-molecule-multiple-target strategy: a novel multifunctional molecule designed to block EGF-r and to exert pro-apoptotic effects 147
Multi-target-Directed Ligands To Combat Neurodegenerative Diseases 147
The bivalent ligand approach as a tool for improving the in vitro anti-Alzheimer multitarget profile of dimebon 146
Novel targets for “old” polyamine analogues: monoamine oxidases and benextramine derivatives 145
Heterocyclic inhibitors of AChE acylation and peripheral sites. 143
Combining galantamine and memantine in dual-target new chemical entities for the treatment of Alzheimer’s disease 143
Structure-Activity Relationships of Acetylcholinesterase Noncovalent Inhibitors Based on a Polyamine Backbone. 4. Futher Investigation on the Inner Spacer. 142
MTDL design strategy in the context of Alzheimer's disease: from lipocrine to memoquin and beyond 141
Multitarget-directed drug design strategy: a novel molecule designed to block epidermal growth factor receptor (EGFR) and to exert proapoptotic effects 141
Circular Dichroism: a Study of Reversible Binding HSA Binding of Lipocrine. 140
Structure-activity relationships of methoctramine-related polyamines as muscarinic antagonist: Effect of replacing the inner polymethylene chain with cyclic moieties 139
Benextramine derivatives as probes to target human monoamine oxidases 139
Targeting Cytokine Release Through the Differential Modulation of Nrf2 and NF-κB Pathways by Electrophilic/Non-Electrophilic Compounds 139
Multi-Target-Direcetd Ligands as acetylcholinesterase inhibitors and nicotinic modulators for Alzheimer's disease 137
Nature-Inspired Hybrids (NIH) Improve Proteostasis by Activating Nrf2-Mediated Protective Pathways in Retinal Pigment Epithelial Cells 136
NRF2 and PPAR-γ Pathways in Oligodendrocyte Progenitors: Focus on Ros Protection, Mitochondrial Biogenesis and Promotion of Cell Differentiation 136
Polymethylene tetraamine backbone as template for the development of biologically active polyamines 134
Natural-product-inspired modulators of Alzheimer’s disease: focus on amyloid and oxidative stress 134
Structure-Activity Relationships of New Acetylcholinesterase Noncovalent Inhibitors Based on a Polyamine Backbone 134
Polyamines may modulate both G protein-coupled receptors and G proteins 131
From dual binding site acetylcholinesterase inhibitors to multi-target-directed ligands (MTDLs): a step forward in the treatment of Alzheimer's disease 130
Nature-inspired Nrf2 activators in retinal pigment epithelial cells: a source for therapeutics in age-related macular degeneration 130
Methoctramine analogues inhibit responses to capsaicin and protons in rat dorsal root ganglion neurons 130
A nature‐inspired nrf2 activator protects retinal explants from oxidative stress and neurodegeneration 130
Methoctramine-related polyamines as antinociceptive agents 129
Methoctramine analogues inhibit responses to capsaicin in DRG neurons and cloned TRPV1 129
EVALUATION OF NOVEL POLYAMINE AND MEMANTINE-DERIVATIVE COMPOUNDS TARGETING NMDA RECEPTORS FOR ALZHEIMER'S DISEASE TREATMENT 128
Polyamines in Drug Discovery: From the Universal Template Approach to the Multitarget-Directed Ligand Design Strategy 127
Discovery of multipotent drugs for the teratment of Alzheimer's disease 125
Synthetic polyamines: an overview of their multiple biological activities. 125
Rational design of multitarget-directed antioxidants: merging memoquin and lipocrine molecular frameworks 125
Recent advances in alpha1-adrenoreceptor antagonists as pharmacological tools and therapeutic agents. 123
Role of Fyn Kinase Inhibitors in Switching Neuroinflammatory Pathways 123
In vitro methods for characterizing new multi-potent compounds for Alzheimer’s disease 119
Controlled Iontophoretic Delivery in Vitro and in Vivo of ARN14140 - A Multitarget Compound for Alzheimer's Disease 117
Tacrine Derivatives and Alzheimer's Disease 116
Rational design of dimebon bivalent ligands against Alzheimer’s disease 110
Exploiting RNA as anticancer target for synthetic polyamines 110
Functionalized Cannabinoid Subtype 2 Receptor Ligands: Fluorescent, PET, Photochromic and Covalent Molecular Probes 109
Reversible HSA binding of lipocrine: a circular dichroism study. 108
Synthesis of monomeric derivatives to probe Memoquin bivalent interactions 107
Methoctramine analogues inhibit capsaicin induced currents in dorsal root ganglia and Xenopus oocytes expressing TRPV1 106
Totale 15.972
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Categoria #
all - tutte 48.151
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 48.151
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021463 0 0 0 0 0 0 0 0 0 102 105 256
2021/20221.920 104 80 124 140 165 126 40 160 67 194 348 372
2022/20231.916 217 287 100 239 112 136 82 95 367 48 168 65
2023/2024775 37 105 49 54 71 217 41 61 26 44 40 30
2024/20252.444 142 287 254 182 528 118 144 78 32 145 110 424
2025/20265.462 413 656 637 460 729 330 600 148 1.173 316 0 0
Totale 17.693