CRIS Current Research Information System

MILELLI, ANDREA
 Distribuzione geografica
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Continente #
NA - Nord America 6.002
AS - Asia 5.376
EU - Europa 4.650
AF - Africa 424
Continente sconosciuto - Info sul continente non disponibili 361
SA - Sud America 299
OC - Oceania 6
Totale 17.118
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Nazione #
US - Stati Uniti d'America 5.875
IT - Italia 1.699
VN - Vietnam 1.437
CN - Cina 1.368
SG - Singapore 1.355
GB - Regno Unito 798
DE - Germania 454
HK - Hong Kong 370
SE - Svezia 369
FR - Francia 258
IN - India 240
BR - Brasile 206
RU - Federazione Russa 184
UA - Ucraina 151
IE - Irlanda 140
NL - Olanda 131
CI - Costa d'Avorio 130
KR - Corea 124
BD - Bangladesh 110
TG - Togo 107
ZA - Sudafrica 92
JP - Giappone 89
FI - Finlandia 69
CA - Canada 64
ES - Italia 63
EE - Estonia 51
SC - Seychelles 47
BE - Belgio 43
BG - Bulgaria 41
JO - Giordania 36
PH - Filippine 36
ID - Indonesia 34
PL - Polonia 34
CH - Svizzera 33
AR - Argentina 32
TH - Thailandia 26
TR - Turchia 26
MX - Messico 25
TW - Taiwan 24
AT - Austria 21
PK - Pakistan 21
HR - Croazia 20
EC - Ecuador 16
IQ - Iraq 16
GR - Grecia 15
NG - Nigeria 15
PT - Portogallo 15
CO - Colombia 13
DK - Danimarca 13
CR - Costa Rica 12
CZ - Repubblica Ceca 11
CL - Cile 10
IR - Iran 9
UZ - Uzbekistan 9
LB - Libano 8
SA - Arabia Saudita 8
EG - Egitto 7
JM - Giamaica 7
MA - Marocco 7
NP - Nepal 6
PE - Perù 6
SM - San Marino 6
VE - Venezuela 6
AU - Australia 5
MY - Malesia 5
PY - Paraguay 5
TN - Tunisia 5
AE - Emirati Arabi Uniti 4
LT - Lituania 4
MT - Malta 4
RO - Romania 4
AZ - Azerbaigian 3
BA - Bosnia-Erzegovina 3
ET - Etiopia 3
HN - Honduras 3
LK - Sri Lanka 3
NI - Nicaragua 3
NO - Norvegia 3
PR - Porto Rico 3
RS - Serbia 3
SV - El Salvador 3
UY - Uruguay 3
BO - Bolivia 2
EU - Europa 2
GT - Guatemala 2
HU - Ungheria 2
IL - Israele 2
KE - Kenya 2
MD - Moldavia 2
MU - Mauritius 2
PS - Palestinian Territory 2
SK - Slovacchia (Repubblica Slovacca) 2
AI - Anguilla 1
AL - Albania 1
AO - Angola 1
BW - Botswana 1
BY - Bielorussia 1
DO - Repubblica Dominicana 1
DZ - Algeria 1
GH - Ghana 1
Totale 16.745
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Città #
Singapore 950
Southend 688
Ashburn 604
Fairfield 487
Chandler 437
Bologna 424
Ho Chi Minh City 355
Hong Kong 341
San Jose 330
Hanoi 316
Santa Clara 274
Houston 247
Ann Arbor 241
Woodbridge 232
Hefei 225
Wilmington 204
Beijing 178
Seattle 175
Princeton 174
Cambridge 159
Dublin 140
Abidjan 130
Boardman 121
Dallas 117
Council Bluffs 115
Dong Ket 113
Milan 111
Lomé 107
Los Angeles 106
New York 100
Seoul 98
Lauterbourg 87
Padova 76
Westminster 73
Jacksonville 70
Redmond 70
Nanjing 68
Rimini 58
Tokyo 58
Helsinki 56
Haiphong 50
Rome 50
Berlin 48
Turin 44
Da Nang 42
Buffalo 41
Jinan 40
Munich 40
Sofia 40
Guangzhou 37
São Paulo 37
Amman 36
Brussels 35
Cesena 34
Redondo Beach 34
Saint Petersburg 34
Shenyang 31
Bremen 30
Shanghai 30
Florence 29
Hebei 29
Medford 28
Phoenix 28
San Diego 28
Stockholm 27
Changsha 24
Johannesburg 24
Portogruaro 24
Bengaluru 23
Forlì 23
Frankfurt am Main 23
Tianjin 23
Zhengzhou 22
Nanchang 21
Des Moines 20
Falls Church 20
Toronto 20
Yubileyny 20
Bern 19
Biên Hòa 19
Orem 19
San Giorgio di Piano 19
Jiaxing 18
London 18
Can Tho 17
Chicago 17
Hangzhou 17
Jakarta 17
Mülheim 17
Palermo 17
Redwood City 17
Barcelona 15
Bari 15
Chiampo 15
Haikou 15
Hải Dương 15
Norwalk 15
Atlanta 14
Cervia 14
Washington 14
Totale 10.467
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Nome #
Discovery of the First-in-Class GSK-3β/HDAC Dual Inhibitor as Disease-Modifying Agent To Combat Alzheimer's Disease. 414
Targeting topoisomerase II with trypthantrin derivatives: Discovery of 7-((2-(dimethylamino)ethyl)amino)indolo[2,1-b]quinazoline-6,12-dione as an antiproliferative agent and to treat cancer 352
PROTAC-Induced Glycogen Synthase Kinase 3β Degradation as a Potential Therapeutic Strategy for Alzheimer’s Disease 346
AR-A014418-based dual Glycogen Synthase Kinase 3β/Histone Deacetylase inhibitors as potential therapeutics for Alzheimer's disease 327
Targeted Protein Degradation for Infectious Diseases: from Basic Biology to Drug Discovery 314
Enriching Proteolysis Targeting Chimeras with a Second Modality: When Two Are Better Than One 309
First in Class Dual Non-ATP-Competitive Glycogen Synthase Kinase 3β/Histone Deacetylase Inhibitors as a Potential Therapeutic to Treat Alzheimer’s Disease 303
Bis(7)-tacrine Derivatives as Multitarget-Directed Ligands: Focus on Anticholinesterase and Antiamyloid Activities 300
Correction: Discovery of the First-in-Class GSK-3β/HDAC Dual Inhibitor as Disease-Modifying Agent to Combat Alzheimer's Disease (ACS Medicinal Chemistry Letters (2019) 10: 4 (469−474) DOI: 10.1021/acsmedchemlett.8b00507) 289
Benextramine and derivatives as novel human monoamine oxidases inhibitors: an integrated approach 273
Deuterium Incorporation Protects Cells from Oxidative Damage 267
Novel Polyamine–Naphthalene Diimide Conjugates Targeting Histone Deacetylases and DNA for Cancer Phenotype Reprogramming 259
Integrating a quinone substructure into histone deacetylase inhibitors to cope with Alzheimer's disease and cancer 251
Treatment with a GSK-3β/HDAC Dual Inhibitor Restores Neuronal Survival and Maturation in an In Vitro and In Vivo Model of CDKL5 Deficiency Disorder 246
PROTAC-INDUCED GLYCOGEN SYNTHASE KINASE 3B DEGRADATION 243
Bovine Serum Amine Oxidase and Polyamine Analogues: Chemical Synthesis and Biological Evaluation Integrated with Molecular Docking and 3-D QSAR Studies 236
Cytotoxicity of methoctramine and methoctramine-related polyamines. 234
Progettazione e sintesi di poliammine a potenziale attività antitumorale 231
DESIGN, SYNTHESIS AND BIOLOGICAL EVALUATION OF SUSTITUTED NAPHTHALENE IMIDES AND DIIMIDES AS ANTICANCER AGENT 229
COMPOSTI ISOTIOCIANATI E ISOSELENCIANATI 214
Cystamine-tacrine dimer: A new multi-target-directed ligand as potential therapeutic agent for Alzheimer's disease treatment. 210
Exploring the activity of polyamine analogues on polyamine and spermine oxidase: methoctramine, a potent and selective inhibitor of polyamine oxidase 208
Progettazione e sintesi di derivati poliamminici per il trattamento della malattia di Alzheimer 205
Targeting Tau Protein with Proximity Inducing Modulators: A New Frontier to Combat Tauopathies 197
Glycogen Synthase Kinase 3β: A New Gold Rush in Anti-Alzheimer’s Disease Multitarget Drug Discovery? 197
Structure-activity relationships of novel substituted naphthalene diimides as anticancer agents 196
Multitargeted drugs discovery: Balancing anti-amyloid and anticholinesterase capacity in a single chemical entity 195
Novel polyamine-based Histone deacetylases-Lysine demethylase 1 dual binding inhibitors 188
Design, synthesis and pharmacological evaluation of multitarget GPR40 agonists/HDAC6 inhibitors for Alzheimer's disease 184
Study of the cytotoxic effects of the new synthetic isothiocyanate CM9 and its fullerene derivative on human T-leukemia cells 181
Design, Synthesis, and biological evaluation of naphtalene diimides derivatives as anticancer agent 179
Novel bis(7)-tacrine derivatives as multitarget ligands: focus on anti-cholinesterase and anti-amyloid activities 177
Synthetic polyamines activating autophagy: Effects on cancer cell death 175
NEWLY SYNTHESIZED POLYAMINE DERIVATIVES AS POTENTIAL ANTICANCER AGENTS 173
Investigating in vitro amyloid peptide 1−42 aggregation: Impact of higher molecular weight stable adducts 173
Exploiting RNA as a new biomolecular target for synthetic polyamines 172
Macrocyclic naphthalene diimides as G-quadruplex binders 171
New rhodol-sulforaphane conjugates as innovative isothiocyanate-based cytotoxic agents for cancer cells 170
Design, synthesis, and biological evaluation of substituted naphtalene imides and diimides as anticancer agents 169
Exploring the effects of isothiocyanates on chemotherapeutic drugs 167
Preparation, characterization and in vitro evaluation of sterically stabilized liposome containing a naphthalenediimide derivative as anticancer agent 164
Designing Dual Transglutaminase 2/Histone Deacetylase Inhibitors Effective at Halting Neuronal Death 163
Combined inhibition of the EGFR/AKT pathways by a novel conjugate of quinazoline with isothiocyanate. 159
Progress in acetylcholinesterase inhibitors for Alzheimer's disease: an update 158
Exploiting the lipoic acid structure in the search for novel multitarget ligands against Alzheimer's disease. 158
Histone Deacetylase Inhibitors as Multitarget Ligands: New Players in Alzheimer's Disease Drug Discovery? 155
Asymmetric Organocatalysis: A Survival Guide to Medicinal Chemists 154
Multifunctional Tacrine Derivatives in Alzheimer’s Disease 154
Oxidative stress in Alzheimer’s disease: are we connecting the dots? 154
Cystamine-tacrine dimer: a new multi-target-directed ligand as potential therapeutic agent for Alzheimer’s disease treatment 154
Novel targets for “old” polyamine analogues: monoamine oxidases and benextramine derivatives 149
Perspectives in Designing Multifunctional Molecules in Antipsychotic Drug Discovery 147
Structure-activity relationships of methoctramine-related polyamines as muscarinic antagonist: Effect of replacing the inner polymethylene chain with cyclic moieties 146
Benextramine derivatives as probes to target human monoamine oxidases 145
In vitro and in vivo evaluation of polymethylene tetraamine derivatives as NMDA receptor channel blockers 144
Overview of the Anticancer Profile of Avenanthramides from Oat 144
Distinct biological responses of metastatic castration resistant prostate cancer cells upon exposure to G-quadruplex interacting naphthalenediimide derivatives 143
Structure-Activity Relationships of Acetylcholinesterase Noncovalent Inhibitors Based on a Polyamine Backbone. 4. Futher Investigation on the Inner Spacer. 142
Hydroxy-substituted trans-cinnamoyl derivatives as multifunctional tools in the context of Alzheimer's disease 142
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Synthetic polyamines as potential amine oxidase inhibitors: a preliminary study. 140
Cytotoxicity of methoctramine-related polyamines 139
Naphthalene diimide-polyamine hybrids as antiproliferative agents: Focus on the architecture of the polyamine chains 139
Application of an ESI-QTOF method for the detailed characterization of GSK-3β inhibitors 138
Structure-Activity Relationships of New Acetylcholinesterase Noncovalent Inhibitors Based on a Polyamine Backbone 136
Novel polyamine analogues: from substrates towards potential inhibitors of monoamine oxidases 136
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- Application of an ESI-MS method enabling the discovery of new non-ATP competitive GSK-3beta inhibitors. 134
Synthetic polyamines: an overview of their multiple biological activities. 129
Application of an ESI-MS method enabling the discovery of new non-ATP competitive GSK-3beta inhibitors. 129
Multi-Target-Directed Drug Design Strategy: Development of new Naphthalene Diimides Bearing Isothiocyanate Functionality As Anticancer Agents 128
Application of ESI-MS method for detailed characterization of GSK-3β inhibitors by monitoring GSM peptide phosphorylation.Angelini Farmaceutici. 127
From Monoamine Oxidase Inhibition to Antiproliferative Activity: New Biological Perspectives for Polyamine Analogs 127
Design, synthesis and biological evaluation of new naphtalene diimides bearing isothiocyanate functionality 122
Tacrine Derivatives and Alzheimer's Disease 121
Synthetic polyamines as potential amine oxidases inhibitors: a preliminary study 120
Novel polyamine analogues: from substrates towards potential inhibitors of monoamine oxidases. 115
Exploiting RNA as anticancer target for synthetic polyamines 112
Direct determination of GSK-3β activity and inhibition by UHPLC-UV-vis diode arrays detector (DAD) 110
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Interactions between new polyamine analogs and bovine serum amine oxidase. 105
Novel asymmetric naphthalenediimide-polyamines conjugates as anticancer agents. 104
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A kinetic study of new polyamine analogs oxidized by bovine serum amine oxidase . 102
"Non-canonical” structures of Braf promoter as novel target in anticancer therapy 101
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Oxidative deamination of new polyamine analogs by bovine serum amine oxidase: a kinetic study 98
Farmaci Tiroidei 96
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Transglutaminases, neuronal cell death and neural repair: Implications for traumatic brain injury and therapeutics 93
Isothiocyanate synthetic analogs: biological activities, structure-activity relationships and synthetic strategies. 89
Tumor vascular targeted liposomal-bortezomib minimizes side effects and increases therapeutic activity in human neuroblastoma 84
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Tacrine-based Multifunctional Agents in Alzheimer's Disease: an Old Story in Continuous Development 82
Topoisomerase II inhibitors in oncology: an updated patent review (2016-present) 78
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Asymmetric 1,4-addition of oxazolones to nitroalkenes by bifunctional cinchona alkaloid thiourea organocatalysts: synthesis of alpha,alpha-disubstituted alpha-amino acids. 67
Totale 16.726
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Categoria #
all - tutte 45.773
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 45.773
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.607 0 55 97 105 173 108 63 111 127 154 320 294
2022/20231.818 196 246 94 223 107 143 79 93 325 56 158 98
2023/2024901 53 106 82 78 66 190 47 38 42 49 87 63
2024/20252.479 150 348 223 181 404 96 176 100 75 159 150 417
2025/20265.942 513 572 549 459 633 287 800 204 1.013 418 254 240
2026/2027320 154 166 0 0 0 0 0 0 0 0 0 0
Totale 17.118