CRIS Current Research Information System

MILELLI, ANDREA
 Distribuzione geografica
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Continente #
NA - Nord America 5.443
AS - Asia 5.200
EU - Europa 4.470
AF - Africa 416
SA - Sud America 284
OC - Oceania 6
Continente sconosciuto - Info sul continente non disponibili 2
Totale 15.821
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Nazione #
US - Stati Uniti d'America 5.389
IT - Italia 1.545
VN - Vietnam 1.421
CN - Cina 1.343
SG - Singapore 1.325
GB - Regno Unito 796
DE - Germania 450
SE - Svezia 367
HK - Hong Kong 362
FR - Francia 255
IN - India 234
BR - Brasile 197
RU - Federazione Russa 184
UA - Ucraina 150
IE - Irlanda 138
CI - Costa d'Avorio 130
NL - Olanda 128
KR - Corea 124
TG - Togo 106
ZA - Sudafrica 92
JP - Giappone 89
FI - Finlandia 69
ES - Italia 60
EE - Estonia 51
BE - Belgio 43
SC - Seychelles 42
BG - Bulgaria 40
JO - Giordania 36
PH - Filippine 35
ID - Indonesia 34
CH - Svizzera 33
AR - Argentina 31
PL - Polonia 31
CA - Canada 28
BD - Bangladesh 26
TH - Thailandia 25
TR - Turchia 25
TW - Taiwan 24
AT - Austria 21
HR - Croazia 20
MX - Messico 19
PK - Pakistan 18
EC - Ecuador 16
IQ - Iraq 16
GR - Grecia 15
PT - Portogallo 15
DK - Danimarca 13
NG - Nigeria 13
CO - Colombia 12
CZ - Repubblica Ceca 11
CL - Cile 9
UZ - Uzbekistan 9
IR - Iran 8
LB - Libano 8
SA - Arabia Saudita 8
EG - Egitto 7
MA - Marocco 7
NP - Nepal 6
PE - Perù 6
SM - San Marino 6
AU - Australia 5
MY - Malesia 5
PY - Paraguay 5
TN - Tunisia 5
AE - Emirati Arabi Uniti 4
LT - Lituania 4
MT - Malta 4
RO - Romania 4
VE - Venezuela 4
AZ - Azerbaigian 3
BA - Bosnia-Erzegovina 3
CR - Costa Rica 3
ET - Etiopia 3
LK - Sri Lanka 3
NO - Norvegia 3
RS - Serbia 3
BO - Bolivia 2
EU - Europa 2
IL - Israele 2
KE - Kenya 2
MU - Mauritius 2
PS - Palestinian Territory 2
SK - Slovacchia (Repubblica Slovacca) 2
UY - Uruguay 2
AL - Albania 1
AO - Angola 1
BW - Botswana 1
BY - Bielorussia 1
DO - Repubblica Dominicana 1
DZ - Algeria 1
GH - Ghana 1
GT - Guatemala 1
HN - Honduras 1
HU - Ungheria 1
KG - Kirghizistan 1
KW - Kuwait 1
KZ - Kazakistan 1
LU - Lussemburgo 1
LY - Libia 1
MD - Moldavia 1
Totale 15.814
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Città #
Singapore 928
Southend 688
Ashburn 574
Fairfield 487
Chandler 433
Bologna 393
Ho Chi Minh City 349
Hong Kong 334
Hanoi 314
San Jose 270
Santa Clara 260
Houston 246
Ann Arbor 241
Woodbridge 232
Hefei 225
Wilmington 204
Seattle 175
Princeton 172
Beijing 168
Cambridge 159
Dublin 138
Abidjan 130
Dong Ket 113
Dallas 110
Boardman 108
Lomé 106
Milan 101
Seoul 98
Los Angeles 92
Lauterbourg 86
New York 81
Padova 76
Westminster 73
Jacksonville 70
Redmond 70
Nanjing 68
Tokyo 58
Helsinki 56
Haiphong 50
Berlin 48
Da Nang 42
Rimini 41
Turin 41
Jinan 40
Munich 40
Rome 39
Sofia 39
Buffalo 38
Council Bluffs 37
Guangzhou 37
Amman 36
Brussels 35
Cesena 34
Saint Petersburg 34
Redondo Beach 33
São Paulo 32
Shenyang 31
Bremen 30
Hebei 29
Shanghai 29
Medford 28
San Diego 28
Florence 27
Stockholm 27
Changsha 24
Johannesburg 24
Portogruaro 24
Forlì 23
Frankfurt am Main 23
Tianjin 23
Bengaluru 22
Nanchang 21
Zhengzhou 21
Des Moines 20
Falls Church 20
Yubileyny 20
Bern 19
Biên Hòa 19
Phoenix 19
San Giorgio di Piano 19
Jiaxing 18
Can Tho 17
Hangzhou 17
Jakarta 17
Mülheim 17
Orem 17
Redwood City 17
London 16
Barcelona 15
Chiampo 15
Haikou 15
Hải Dương 15
Norwalk 15
Palermo 15
Toronto 15
Amsterdam 13
Chicago 13
Dearborn 13
Ravenna 13
Taizhou 13
Totale 10.058
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Nome #
Discovery of the First-in-Class GSK-3β/HDAC Dual Inhibitor as Disease-Modifying Agent To Combat Alzheimer's Disease. 394
Targeting topoisomerase II with trypthantrin derivatives: Discovery of 7-((2-(dimethylamino)ethyl)amino)indolo[2,1-b]quinazoline-6,12-dione as an antiproliferative agent and to treat cancer 333
PROTAC-Induced Glycogen Synthase Kinase 3β Degradation as a Potential Therapeutic Strategy for Alzheimer’s Disease 331
Enriching Proteolysis Targeting Chimeras with a Second Modality: When Two Are Better Than One 300
Bis(7)-tacrine Derivatives as Multitarget-Directed Ligands: Focus on Anticholinesterase and Antiamyloid Activities 297
Targeted Protein Degradation for Infectious Diseases: from Basic Biology to Drug Discovery 289
First in Class Dual Non-ATP-Competitive Glycogen Synthase Kinase 3β/Histone Deacetylase Inhibitors as a Potential Therapeutic to Treat Alzheimer’s Disease 289
Correction: Discovery of the First-in-Class GSK-3β/HDAC Dual Inhibitor as Disease-Modifying Agent to Combat Alzheimer's Disease (ACS Medicinal Chemistry Letters (2019) 10: 4 (469−474) DOI: 10.1021/acsmedchemlett.8b00507) 284
Benextramine and derivatives as novel human monoamine oxidases inhibitors: an integrated approach 265
AR-A014418-based dual Glycogen Synthase Kinase 3β/Histone Deacetylase inhibitors as potential therapeutics for Alzheimer's disease 263
Deuterium Incorporation Protects Cells from Oxidative Damage 251
Novel Polyamine–Naphthalene Diimide Conjugates Targeting Histone Deacetylases and DNA for Cancer Phenotype Reprogramming 250
PROTAC-INDUCED GLYCOGEN SYNTHASE KINASE 3B DEGRADATION 235
Treatment with a GSK-3β/HDAC Dual Inhibitor Restores Neuronal Survival and Maturation in an In Vitro and In Vivo Model of CDKL5 Deficiency Disorder 234
Integrating a quinone substructure into histone deacetylase inhibitors to cope with Alzheimer's disease and cancer 233
Bovine Serum Amine Oxidase and Polyamine Analogues: Chemical Synthesis and Biological Evaluation Integrated with Molecular Docking and 3-D QSAR Studies 230
Cytotoxicity of methoctramine and methoctramine-related polyamines. 228
Progettazione e sintesi di poliammine a potenziale attività antitumorale 226
DESIGN, SYNTHESIS AND BIOLOGICAL EVALUATION OF SUSTITUTED NAPHTHALENE IMIDES AND DIIMIDES AS ANTICANCER AGENT 221
COMPOSTI ISOTIOCIANATI E ISOSELENCIANATI 207
Exploring the activity of polyamine analogues on polyamine and spermine oxidase: methoctramine, a potent and selective inhibitor of polyamine oxidase 200
Glycogen Synthase Kinase 3β: A New Gold Rush in Anti-Alzheimer’s Disease Multitarget Drug Discovery? 195
Progettazione e sintesi di derivati poliamminici per il trattamento della malattia di Alzheimer 193
Structure-activity relationships of novel substituted naphthalene diimides as anticancer agents 193
Multitargeted drugs discovery: Balancing anti-amyloid and anticholinesterase capacity in a single chemical entity 192
Cystamine-tacrine dimer: A new multi-target-directed ligand as potential therapeutic agent for Alzheimer's disease treatment. 178
Novel polyamine-based Histone deacetylases-Lysine demethylase 1 dual binding inhibitors 178
Design, Synthesis, and biological evaluation of naphtalene diimides derivatives as anticancer agent 177
Study of the cytotoxic effects of the new synthetic isothiocyanate CM9 and its fullerene derivative on human T-leukemia cells 176
Novel bis(7)-tacrine derivatives as multitarget ligands: focus on anti-cholinesterase and anti-amyloid activities 173
Synthetic polyamines activating autophagy: Effects on cancer cell death 168
Macrocyclic naphthalene diimides as G-quadruplex binders 168
NEWLY SYNTHESIZED POLYAMINE DERIVATIVES AS POTENTIAL ANTICANCER AGENTS 166
Targeting Tau Protein with Proximity Inducing Modulators: A New Frontier to Combat Tauopathies 165
Exploiting RNA as a new biomolecular target for synthetic polyamines 165
Design, synthesis, and biological evaluation of substituted naphtalene imides and diimides as anticancer agents 164
Investigating in vitro amyloid peptide 1−42 aggregation: Impact of higher molecular weight stable adducts 162
Designing Dual Transglutaminase 2/Histone Deacetylase Inhibitors Effective at Halting Neuronal Death 158
Preparation, characterization and in vitro evaluation of sterically stabilized liposome containing a naphthalenediimide derivative as anticancer agent 158
New rhodol-sulforaphane conjugates as innovative isothiocyanate-based cytotoxic agents for cancer cells 155
Progress in acetylcholinesterase inhibitors for Alzheimer's disease: an update 155
Exploiting the lipoic acid structure in the search for novel multitarget ligands against Alzheimer's disease. 154
Exploring the effects of isothiocyanates on chemotherapeutic drugs 153
Multifunctional Tacrine Derivatives in Alzheimer’s Disease 152
Cystamine-tacrine dimer: a new multi-target-directed ligand as potential therapeutic agent for Alzheimer’s disease treatment 151
Oxidative stress in Alzheimer’s disease: are we connecting the dots? 150
Combined inhibition of the EGFR/AKT pathways by a novel conjugate of quinazoline with isothiocyanate. 150
Histone Deacetylase Inhibitors as Multitarget Ligands: New Players in Alzheimer's Disease Drug Discovery? 149
Asymmetric Organocatalysis: A Survival Guide to Medicinal Chemists 147
Novel targets for “old” polyamine analogues: monoamine oxidases and benextramine derivatives 145
In vitro and in vivo evaluation of polymethylene tetraamine derivatives as NMDA receptor channel blockers 143
Structure-Activity Relationships of Acetylcholinesterase Noncovalent Inhibitors Based on a Polyamine Backbone. 4. Futher Investigation on the Inner Spacer. 142
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Perspectives in Designing Multifunctional Molecules in Antipsychotic Drug Discovery 141
Distinct biological responses of metastatic castration resistant prostate cancer cells upon exposure to G-quadruplex interacting naphthalenediimide derivatives 140
Structure-activity relationships of methoctramine-related polyamines as muscarinic antagonist: Effect of replacing the inner polymethylene chain with cyclic moieties 139
Benextramine derivatives as probes to target human monoamine oxidases 139
Synthetic polyamines as potential amine oxidase inhibitors: a preliminary study. 137
Overview of the Anticancer Profile of Avenanthramides from Oat 137
Cytotoxicity of methoctramine-related polyamines 136
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Structure-Activity Relationships of New Acetylcholinesterase Noncovalent Inhibitors Based on a Polyamine Backbone 134
Novel polyamine analogues: from substrates towards potential inhibitors of monoamine oxidases 134
- Application of an ESI-MS method enabling the discovery of new non-ATP competitive GSK-3beta inhibitors. 131
Naphthalene diimide-polyamine hybrids as antiproliferative agents: Focus on the architecture of the polyamine chains 130
Multi-Target-Directed Drug Design Strategy: Development of new Naphthalene Diimides Bearing Isothiocyanate Functionality As Anticancer Agents 127
Application of an ESI-MS method enabling the discovery of new non-ATP competitive GSK-3beta inhibitors. 126
Synthetic polyamines: an overview of their multiple biological activities. 125
Application of ESI-MS method for detailed characterization of GSK-3β inhibitors by monitoring GSM peptide phosphorylation.Angelini Farmaceutici. 125
Application of an ESI-QTOF method for the detailed characterization of GSK-3β inhibitors 123
From Monoamine Oxidase Inhibition to Antiproliferative Activity: New Biological Perspectives for Polyamine Analogs 123
Hydroxy-substituted trans-cinnamoyl derivatives as multifunctional tools in the context of Alzheimer's disease 120
Design, synthesis and pharmacological evaluation of multitarget GPR40 agonists/HDAC6 inhibitors for Alzheimer's disease 118
Synthetic polyamines as potential amine oxidases inhibitors: a preliminary study 116
Tacrine Derivatives and Alzheimer's Disease 116
Design, synthesis and biological evaluation of new naphtalene diimides bearing isothiocyanate functionality 115
Novel polyamine analogues: from substrates towards potential inhibitors of monoamine oxidases. 112
Exploiting RNA as anticancer target for synthetic polyamines 110
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Interactions between new polyamine analogs and bovine serum amine oxidase. 103
Novel asymmetric naphthalenediimide-polyamines conjugates as anticancer agents. 101
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Direct determination of GSK-3β activity and inhibition by UHPLC-UV-vis diode arrays detector (DAD) 98
A kinetic study of new polyamine analogs oxidized by bovine serum amine oxidase . 97
"Non-canonical” structures of Braf promoter as novel target in anticancer therapy 97
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Oxidative deamination of new polyamine analogs by bovine serum amine oxidase: a kinetic study 92
Farmaci Tiroidei 91
Transglutaminases, neuronal cell death and neural repair: Implications for traumatic brain injury and therapeutics 88
Isothiocyanate synthetic analogs: biological activities, structure-activity relationships and synthetic strategies. 86
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Tacrine-based Multifunctional Agents in Alzheimer's Disease: an Old Story in Continuous Development 79
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Tumor vascular targeted liposomal-bortezomib minimizes side effects and increases therapeutic activity in human neuroblastoma 75
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Totale 15.951
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Categoria #
all - tutte 41.073
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 41.073
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021367 0 0 0 0 0 0 0 0 0 61 53 253
2021/20221.702 95 55 97 105 173 108 63 111 127 154 320 294
2022/20231.803 193 244 92 222 107 142 79 93 322 56 155 98
2023/2024895 53 106 81 76 66 188 47 38 42 48 87 63
2024/20252.464 149 344 223 179 401 95 176 100 75 159 148 415
2025/20265.354 512 571 547 459 631 284 797 204 1.006 343 0 0
Totale 16.174