CRIS Current Research Information System

MILELLI, ANDREA
 Distribuzione geografica
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Continente #
NA - Nord America 5.762
AS - Asia 5.322
EU - Europa 4.599
AF - Africa 419
SA - Sud America 294
OC - Oceania 6
Continente sconosciuto - Info sul continente non disponibili 2
Totale 16.404
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Nazione #
US - Stati Uniti d'America 5.682
IT - Italia 1.656
VN - Vietnam 1.428
CN - Cina 1.357
SG - Singapore 1.342
GB - Regno Unito 797
DE - Germania 454
SE - Svezia 369
HK - Hong Kong 367
FR - Francia 257
IN - India 239
BR - Brasile 205
RU - Federazione Russa 184
UA - Ucraina 151
IE - Irlanda 140
CI - Costa d'Avorio 130
NL - Olanda 129
KR - Corea 124
TG - Togo 107
BD - Bangladesh 97
ZA - Sudafrica 92
JP - Giappone 89
FI - Finlandia 69
ES - Italia 62
EE - Estonia 51
CA - Canada 46
BE - Belgio 43
SC - Seychelles 42
BG - Bulgaria 41
JO - Giordania 36
PH - Filippine 36
ID - Indonesia 34
CH - Svizzera 33
PL - Polonia 32
AR - Argentina 31
TR - Turchia 26
TH - Thailandia 25
TW - Taiwan 24
MX - Messico 22
AT - Austria 21
HR - Croazia 20
PK - Pakistan 19
EC - Ecuador 16
IQ - Iraq 16
GR - Grecia 15
NG - Nigeria 15
PT - Portogallo 15
DK - Danimarca 13
CO - Colombia 12
CZ - Repubblica Ceca 11
CL - Cile 10
UZ - Uzbekistan 9
IR - Iran 8
LB - Libano 8
SA - Arabia Saudita 8
EG - Egitto 7
MA - Marocco 7
NP - Nepal 6
PE - Perù 6
SM - San Marino 6
AU - Australia 5
MY - Malesia 5
PY - Paraguay 5
TN - Tunisia 5
AE - Emirati Arabi Uniti 4
CR - Costa Rica 4
LT - Lituania 4
MT - Malta 4
RO - Romania 4
VE - Venezuela 4
AZ - Azerbaigian 3
BA - Bosnia-Erzegovina 3
ET - Etiopia 3
LK - Sri Lanka 3
NO - Norvegia 3
RS - Serbia 3
UY - Uruguay 3
BO - Bolivia 2
EU - Europa 2
GT - Guatemala 2
HN - Honduras 2
IL - Israele 2
KE - Kenya 2
MD - Moldavia 2
MU - Mauritius 2
PS - Palestinian Territory 2
SK - Slovacchia (Repubblica Slovacca) 2
AL - Albania 1
AO - Angola 1
BW - Botswana 1
BY - Bielorussia 1
DO - Repubblica Dominicana 1
DZ - Algeria 1
GH - Ghana 1
HU - Ungheria 1
KG - Kirghizistan 1
KW - Kuwait 1
KZ - Kazakistan 1
LU - Lussemburgo 1
LY - Libia 1
Totale 16.395
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Città #
Singapore 939
Southend 688
Ashburn 592
Fairfield 487
Chandler 437
Bologna 416
Ho Chi Minh City 353
Hong Kong 339
San Jose 328
Hanoi 315
Santa Clara 265
Houston 246
Ann Arbor 241
Woodbridge 232
Hefei 225
Wilmington 204
Seattle 175
Beijing 174
Princeton 174
Cambridge 159
Dublin 140
Abidjan 130
Boardman 120
Dallas 116
Dong Ket 113
Milan 109
Lomé 107
Los Angeles 105
New York 100
Seoul 98
Lauterbourg 87
Padova 76
Westminster 73
Jacksonville 70
Redmond 70
Nanjing 68
Tokyo 58
Helsinki 56
Rimini 56
Council Bluffs 55
Haiphong 50
Berlin 48
Rome 47
Da Nang 42
Turin 42
Buffalo 40
Jinan 40
Munich 40
Sofia 40
Guangzhou 37
São Paulo 37
Amman 36
Brussels 35
Cesena 34
Redondo Beach 34
Saint Petersburg 34
Shenyang 31
Bremen 30
Shanghai 30
Florence 29
Hebei 29
Medford 28
San Diego 28
Stockholm 27
Changsha 24
Johannesburg 24
Phoenix 24
Portogruaro 24
Bengaluru 23
Forlì 23
Frankfurt am Main 23
Tianjin 23
Zhengzhou 22
Nanchang 21
Des Moines 20
Falls Church 20
Yubileyny 20
Bern 19
Biên Hòa 19
Orem 19
San Giorgio di Piano 19
Toronto 19
Jiaxing 18
Can Tho 17
Hangzhou 17
Jakarta 17
London 17
Mülheim 17
Palermo 17
Redwood City 17
Barcelona 15
Chiampo 15
Haikou 15
Hải Dương 15
Norwalk 15
Cervia 14
Amsterdam 13
Atlanta 13
Bari 13
Chicago 13
Totale 10.328
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Nome #
Discovery of the First-in-Class GSK-3β/HDAC Dual Inhibitor as Disease-Modifying Agent To Combat Alzheimer's Disease. 402
PROTAC-Induced Glycogen Synthase Kinase 3β Degradation as a Potential Therapeutic Strategy for Alzheimer’s Disease 339
Targeting topoisomerase II with trypthantrin derivatives: Discovery of 7-((2-(dimethylamino)ethyl)amino)indolo[2,1-b]quinazoline-6,12-dione as an antiproliferative agent and to treat cancer 338
AR-A014418-based dual Glycogen Synthase Kinase 3β/Histone Deacetylase inhibitors as potential therapeutics for Alzheimer's disease 312
Targeted Protein Degradation for Infectious Diseases: from Basic Biology to Drug Discovery 307
Enriching Proteolysis Targeting Chimeras with a Second Modality: When Two Are Better Than One 304
Bis(7)-tacrine Derivatives as Multitarget-Directed Ligands: Focus on Anticholinesterase and Antiamyloid Activities 297
First in Class Dual Non-ATP-Competitive Glycogen Synthase Kinase 3β/Histone Deacetylase Inhibitors as a Potential Therapeutic to Treat Alzheimer’s Disease 294
Correction: Discovery of the First-in-Class GSK-3β/HDAC Dual Inhibitor as Disease-Modifying Agent to Combat Alzheimer's Disease (ACS Medicinal Chemistry Letters (2019) 10: 4 (469−474) DOI: 10.1021/acsmedchemlett.8b00507) 287
Benextramine and derivatives as novel human monoamine oxidases inhibitors: an integrated approach 271
Deuterium Incorporation Protects Cells from Oxidative Damage 265
Novel Polyamine–Naphthalene Diimide Conjugates Targeting Histone Deacetylases and DNA for Cancer Phenotype Reprogramming 256
Integrating a quinone substructure into histone deacetylase inhibitors to cope with Alzheimer's disease and cancer 247
Treatment with a GSK-3β/HDAC Dual Inhibitor Restores Neuronal Survival and Maturation in an In Vitro and In Vivo Model of CDKL5 Deficiency Disorder 243
PROTAC-INDUCED GLYCOGEN SYNTHASE KINASE 3B DEGRADATION 237
Bovine Serum Amine Oxidase and Polyamine Analogues: Chemical Synthesis and Biological Evaluation Integrated with Molecular Docking and 3-D QSAR Studies 233
Cytotoxicity of methoctramine and methoctramine-related polyamines. 231
Progettazione e sintesi di poliammine a potenziale attività antitumorale 228
DESIGN, SYNTHESIS AND BIOLOGICAL EVALUATION OF SUSTITUTED NAPHTHALENE IMIDES AND DIIMIDES AS ANTICANCER AGENT 224
COMPOSTI ISOTIOCIANATI E ISOSELENCIANATI 210
Cystamine-tacrine dimer: A new multi-target-directed ligand as potential therapeutic agent for Alzheimer's disease treatment. 206
Exploring the activity of polyamine analogues on polyamine and spermine oxidase: methoctramine, a potent and selective inhibitor of polyamine oxidase 205
Progettazione e sintesi di derivati poliamminici per il trattamento della malattia di Alzheimer 202
Glycogen Synthase Kinase 3β: A New Gold Rush in Anti-Alzheimer’s Disease Multitarget Drug Discovery? 196
Multitargeted drugs discovery: Balancing anti-amyloid and anticholinesterase capacity in a single chemical entity 194
Structure-activity relationships of novel substituted naphthalene diimides as anticancer agents 194
Targeting Tau Protein with Proximity Inducing Modulators: A New Frontier to Combat Tauopathies 187
Novel polyamine-based Histone deacetylases-Lysine demethylase 1 dual binding inhibitors 182
Study of the cytotoxic effects of the new synthetic isothiocyanate CM9 and its fullerene derivative on human T-leukemia cells 180
Design, Synthesis, and biological evaluation of naphtalene diimides derivatives as anticancer agent 178
Novel bis(7)-tacrine derivatives as multitarget ligands: focus on anti-cholinesterase and anti-amyloid activities 176
Synthetic polyamines activating autophagy: Effects on cancer cell death 173
Macrocyclic naphthalene diimides as G-quadruplex binders 170
Design, synthesis and pharmacological evaluation of multitarget GPR40 agonists/HDAC6 inhibitors for Alzheimer's disease 169
NEWLY SYNTHESIZED POLYAMINE DERIVATIVES AS POTENTIAL ANTICANCER AGENTS 169
Investigating in vitro amyloid peptide 1−42 aggregation: Impact of higher molecular weight stable adducts 169
Design, synthesis, and biological evaluation of substituted naphtalene imides and diimides as anticancer agents 167
New rhodol-sulforaphane conjugates as innovative isothiocyanate-based cytotoxic agents for cancer cells 166
Exploiting RNA as a new biomolecular target for synthetic polyamines 165
Preparation, characterization and in vitro evaluation of sterically stabilized liposome containing a naphthalenediimide derivative as anticancer agent 162
Exploring the effects of isothiocyanates on chemotherapeutic drugs 160
Designing Dual Transglutaminase 2/Histone Deacetylase Inhibitors Effective at Halting Neuronal Death 159
Progress in acetylcholinesterase inhibitors for Alzheimer's disease: an update 157
Exploiting the lipoic acid structure in the search for novel multitarget ligands against Alzheimer's disease. 157
Combined inhibition of the EGFR/AKT pathways by a novel conjugate of quinazoline with isothiocyanate. 155
Cystamine-tacrine dimer: a new multi-target-directed ligand as potential therapeutic agent for Alzheimer’s disease treatment 153
Multifunctional Tacrine Derivatives in Alzheimer’s Disease 152
Oxidative stress in Alzheimer’s disease: are we connecting the dots? 152
Histone Deacetylase Inhibitors as Multitarget Ligands: New Players in Alzheimer's Disease Drug Discovery? 152
Asymmetric Organocatalysis: A Survival Guide to Medicinal Chemists 150
Novel targets for “old” polyamine analogues: monoamine oxidases and benextramine derivatives 147
Structure-activity relationships of methoctramine-related polyamines as muscarinic antagonist: Effect of replacing the inner polymethylene chain with cyclic moieties 146
Perspectives in Designing Multifunctional Molecules in Antipsychotic Drug Discovery 145
In vitro and in vivo evaluation of polymethylene tetraamine derivatives as NMDA receptor channel blockers 143
Structure-Activity Relationships of Acetylcholinesterase Noncovalent Inhibitors Based on a Polyamine Backbone. 4. Futher Investigation on the Inner Spacer. 142
Overview of the Anticancer Profile of Avenanthramides from Oat 142
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Distinct biological responses of metastatic castration resistant prostate cancer cells upon exposure to G-quadruplex interacting naphthalenediimide derivatives 141
Benextramine derivatives as probes to target human monoamine oxidases 140
Synthetic polyamines as potential amine oxidase inhibitors: a preliminary study. 138
Hydroxy-substituted trans-cinnamoyl derivatives as multifunctional tools in the context of Alzheimer's disease 138
Cytotoxicity of methoctramine-related polyamines 137
Novel polyamine analogues: from substrates towards potential inhibitors of monoamine oxidases 136
Structure-Activity Relationships of New Acetylcholinesterase Noncovalent Inhibitors Based on a Polyamine Backbone 135
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Application of an ESI-QTOF method for the detailed characterization of GSK-3β inhibitors 134
- Application of an ESI-MS method enabling the discovery of new non-ATP competitive GSK-3beta inhibitors. 133
Naphthalene diimide-polyamine hybrids as antiproliferative agents: Focus on the architecture of the polyamine chains 132
Application of an ESI-MS method enabling the discovery of new non-ATP competitive GSK-3beta inhibitors. 128
Multi-Target-Directed Drug Design Strategy: Development of new Naphthalene Diimides Bearing Isothiocyanate Functionality As Anticancer Agents 127
From Monoamine Oxidase Inhibition to Antiproliferative Activity: New Biological Perspectives for Polyamine Analogs 127
Synthetic polyamines: an overview of their multiple biological activities. 126
Application of ESI-MS method for detailed characterization of GSK-3β inhibitors by monitoring GSM peptide phosphorylation.Angelini Farmaceutici. 126
Tacrine Derivatives and Alzheimer's Disease 118
Synthetic polyamines as potential amine oxidases inhibitors: a preliminary study 117
Design, synthesis and biological evaluation of new naphtalene diimides bearing isothiocyanate functionality 117
Novel polyamine analogues: from substrates towards potential inhibitors of monoamine oxidases. 113
Exploiting RNA as anticancer target for synthetic polyamines 111
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Interactions between new polyamine analogs and bovine serum amine oxidase. 105
Direct determination of GSK-3β activity and inhibition by UHPLC-UV-vis diode arrays detector (DAD) 105
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Novel asymmetric naphthalenediimide-polyamines conjugates as anticancer agents. 102
A kinetic study of new polyamine analogs oxidized by bovine serum amine oxidase . 100
"Non-canonical” structures of Braf promoter as novel target in anticancer therapy 99
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Oxidative deamination of new polyamine analogs by bovine serum amine oxidase: a kinetic study 94
Farmaci Tiroidei 93
Transglutaminases, neuronal cell death and neural repair: Implications for traumatic brain injury and therapeutics 89
Isothiocyanate synthetic analogs: biological activities, structure-activity relationships and synthetic strategies. 87
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Tacrine-based Multifunctional Agents in Alzheimer's Disease: an Old Story in Continuous Development 81
Tumor vascular targeted liposomal-bortezomib minimizes side effects and increases therapeutic activity in human neuroblastoma 80
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Topoisomerase II inhibitors in oncology: an updated patent review (2016-present) 71
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Totale 16.419
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Categoria #
all - tutte 43.852
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 43.852
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021253 0 0 0 0 0 0 0 0 0 0 0 253
2021/20221.702 95 55 97 105 173 108 63 111 127 154 320 294
2022/20231.818 196 246 94 223 107 143 79 93 325 56 158 98
2023/2024901 53 106 82 78 66 190 47 38 42 49 87 63
2024/20252.479 150 348 223 181 404 96 176 100 75 159 150 417
2025/20265.904 513 572 549 459 633 287 800 204 1.013 418 254 202
Totale 16.760