CRIS Current Research Information System

RUGOLO, MICHELA
 Distribuzione geografica
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Continente #
NA - Nord America 4.568
EU - Europa 3.514
AS - Asia 2.970
AF - Africa 311
SA - Sud America 149
OC - Oceania 8
Continente sconosciuto - Info sul continente non disponibili 6
Totale 11.526
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Nazione #
US - Stati Uniti d'America 4.526
CN - Cina 958
SG - Singapore 889
GB - Regno Unito 816
IT - Italia 703
VN - Vietnam 510
DE - Germania 448
SE - Svezia 447
UA - Ucraina 260
HK - Hong Kong 206
RU - Federazione Russa 202
IN - India 182
FR - Francia 148
CI - Costa d'Avorio 123
IE - Irlanda 115
BR - Brasile 112
TG - Togo 72
NL - Olanda 68
CH - Svizzera 64
ZA - Sudafrica 64
JP - Giappone 63
EE - Estonia 56
JO - Giordania 50
KR - Corea 46
SC - Seychelles 38
BG - Bulgaria 31
FI - Finlandia 30
CA - Canada 25
AR - Argentina 19
BE - Belgio 18
AT - Austria 16
PL - Polonia 16
MX - Messico 14
ID - Indonesia 13
ES - Italia 12
BY - Bielorussia 11
PK - Pakistan 11
GR - Grecia 10
IR - Iran 10
BD - Bangladesh 9
CZ - Repubblica Ceca 8
AU - Australia 7
EC - Ecuador 7
HR - Croazia 6
LB - Libano 6
NG - Nigeria 6
RO - Romania 6
SK - Slovacchia (Repubblica Slovacca) 6
DK - Danimarca 5
AE - Emirati Arabi Uniti 4
TR - Turchia 4
CL - Cile 3
DZ - Algeria 3
LT - Lituania 3
PE - Perù 3
PT - Portogallo 3
XK - ???statistics.table.value.countryCode.XK??? 3
CO - Colombia 2
DO - Repubblica Dominicana 2
EG - Egitto 2
EU - Europa 2
NO - Norvegia 2
PH - Filippine 2
SI - Slovenia 2
A2 - ???statistics.table.value.countryCode.A2??? 1
BO - Bolivia 1
GN - Guinea 1
GT - Guatemala 1
IL - Israele 1
IQ - Iraq 1
KG - Kirghizistan 1
LU - Lussemburgo 1
MA - Marocco 1
MD - Moldavia 1
MN - Mongolia 1
PG - Papua Nuova Guinea 1
PY - Paraguay 1
SA - Arabia Saudita 1
TN - Tunisia 1
TW - Taiwan 1
UZ - Uzbekistan 1
VE - Venezuela 1
Totale 11.526
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Città #
Southend 700
Singapore 577
Ashburn 450
Fairfield 440
Chandler 435
Ann Arbor 242
Santa Clara 237
Wilmington 221
Bologna 207
Woodbridge 206
Hong Kong 204
Houston 193
Seattle 190
Jacksonville 176
Princeton 160
Hefei 141
Cambridge 138
Abidjan 123
Beijing 120
Dong Ket 118
Dublin 113
Boardman 106
Padova 74
Lomé 72
New York 72
Westminster 72
Los Angeles 69
Ho Chi Minh City 65
Nanjing 59
Bern 57
Tokyo 57
Berlin 55
Amman 50
Jinan 45
Seoul 45
Saint Petersburg 43
Redmond 41
Turin 40
Changsha 34
Dallas 34
Mülheim 32
Medford 31
Milan 31
Buffalo 29
Sofia 29
Hanoi 27
Hebei 27
San Diego 27
Guangzhou 24
Shanghai 24
Shenyang 24
Tianjin 22
Nanchang 21
Redondo Beach 21
Florence 20
Helsinki 20
Parma 20
Falls Church 19
Mahé 19
Redwood City 19
Brussels 17
Dearborn 17
Rome 17
Jiaxing 16
Bengaluru 15
São Paulo 15
Zhengzhou 15
Munich 14
Norwalk 14
Phoenix 14
Taizhou 14
Des Moines 13
Taiyuan 13
Verona 13
Amsterdam 12
Kuban 12
Yubileyny 12
Falkenstein 11
Fuzhou 11
Haikou 11
Minsk 11
Ningbo 11
Argelato 10
Hangzhou 10
Jakarta 10
London 10
Mountain View 10
Nuremberg 10
Pune 10
Chicago 9
Modena 9
Olalla 9
Shenzhen 9
Boston 8
Frankfurt am Main 8
Toronto 8
Vienna 8
Warsaw 8
Chennai 7
Paris 7
Totale 7.425
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Nome #
'Behr syndrome' with OPA1 compound heterozygote mutations 287
Coenzyme Q biosynthesis inhibition induces HIF-1α stabilization and metabolic switch toward glycolysis 270
Different mtDNA mutations modify tumor progression in dependence of the degree of respiratory complex I impairment 240
A clinically complex form of dominant optic atrophy (OPA8) maps on chromosome 16. 227
Eight human OPA1 isoforms, long and short: What are they for? 226
Respiratory complex I is essential to induce a Warburg profile in mitochondria-defective tumor cells 223
Apoptosis induced by staurosporine in ECV304 cells requires cell shrinkage and upregulation of Cl- conductance 218
An inherited mitochondrial DNA disruptive mutation shifts to homoplasmy in oncocytic tumor cells. 214
The antioxidant function of Bcl-2 preserves cytoskeletal stability of cells with defective respiratory complex I. 208
Alterations in the supramolecular interactions of respiratory chain complexes and enhanced superoxide production by the cytochrome b Y278C mutation which causes a multisystem disorder 200
Deciphering OPA1 mutations pathogenicity by combined analysis of human, mouse and yeast cell models 199
The background of mitochondrial DNA haplogroup J increases the sensitivity of Leber's hereditary optic neuropathy cells to 2,5-hexanedione toxicity. 198
Defective oxidative phosphorylation in thyroid oncocytic carcinoma is associated with pathogenic mitochondrial DNA mutations affecting complexes I and III 195
pH difference across the outer mitochondrial membrane measured with a green fluorescent protein mutant 192
Clonal expansion of mtDNA deletions: different disease models assessed by digital droplet PCR in single muscle cells. 185
Caspase-independent death of Leber's hereditary optic neuropathy cybrids is driven by energetic failure and mediated by AIF and Endonuclease G. 181
Effect of energetic stress and the ceramide analogue C6-ceramide on thyroid oncocytoma cell lines. 180
Reactive Oxygen Species Produced by Mutated Mitochondrial Respiratory Chains of Entire Cells Monitored Using Modified Microelectrodes 179
ATP depletion and caspase independent death of cybrids bearing Leber's Hereditary Optic neuropathy MTDNA mutations incubated in galactose medium. A model for endonuclease G-mediated apoptosis 174
Cell death of fibroblasts derived from patients with Leber’s hereditary optic neuropathy mtDNA mutations 168
Disruptive mitochondrial DNA mutations in complex I subunits are markers of oncocytic phenotype in thyroid tumours. 168
Effect of energetic stress and the ceramide analogue C6-ceramide on thyroid oncocytoma cell lines 167
OPA1 Isoforms in the Hierarchical Organization of Mitochondrial Functions 167
Syndromic parkinsonism and dementia associated with OPA1 missense mutations 167
The cytochrome B p.278Y>C mutation causative of a multisystem disorder enhances superoxide production and alters supramolecular interactions of respiratory chain complexes 165
Drug repositioning as a therapeutic strategy for neurodegenerations associated with OPA1 mutations 165
A cellular model for cancer progression: Role of mitochondrial mutations and metabolism 162
A Mutation Threshold Distinguishes the Antitumorigenic Effects of the Mitochondrial Gene MTND1, an Oncojanus Function 162
Gamma rays induce a p53-independent mitochondrial biogenesis that is counter-regulated by HIF1α. 162
Rare mtDNA variants in Leber hereditary optic neuropathy families with recurrence of myoclonus. 161
Metabolomics hallmarks OPA1 variants correlating with their in-vitro phenotype and predicting clinical severity 161
Effect of energetic stress and the ceramide analogue C6-ceramide on thyroid oncocytoma cell lines 158
Evaluation of the energetic efficiency of cells derived from patients with dominant optic neuropathy (DOA). 154
OPA1: how much do we know to approach therapy? 153
Green tea modulates a-1-adrenergic stimulated glucose transport in cultured cardiomyocytes via protein kinase C beta and delta isoforms 153
A novel in-frame 18-bp microdeletion in MT-CYB causes a multisystem disorder with prominent exercise intolerance. 152
Green Tea Modulates Alpha-1-Adrenergic Stimulated Glucose Transport in Cultured Rat Cardiomyocytes 148
GLUCOSE TRANSPORT ACTIVATION IN HUMAN HEMATOPOIETIC CELLS M07e IS MODULATED BY CYTOSOLIC CALCIUM AND CALMODULIN 148
Bioenergetics shapes cellular death pathways in Leber’s hereditary optic neuropathy: a model of mitochondrial neurodegeneration 147
Fine-tuning of the respiratory complexes stability and supercomplexes assembly in cells defective of complex III 147
Protection against oxidant-induced apoptosis by exogenous glutathione in Leber Hereditary Optic Neuropathy cybrids. 145
Biochimica 144
The genetic and metabolic signature of oncocytic transformation implicates HIF1alpha destabilization 144
Determination of mitochondrial fusion in fibroblasts from dominant optic atrophy patients bearing the c.2708delttag OPA1 mutation 143
OPA 1 mutations induce mitochondrial DNA instability and optic atrophy "plus" phenotypes 139
OPA3, a new regulator of mitochondrial fission? 136
AIF and endonuclease G are involved in the caspase-indepenent death of cybrids with LHON mutations 136
Respiratory complex I dysfunction due to mitochondrial DNA mutations shifts the voltage threshold for opening of the permeability transition pore toward resting levels 135
Dominant optic neuropathy: analysis of the energetic efficiency and mitochondrial dynamics 134
Mitochondrial DNA mutations in relation to cancer: the model of thyroid oncocytoma 134
Mitochondria: Biogenesis and mitophagy balance in segregation and clonal expansion of mitochondrial DNA mutations 133
Learning from oncocytic tumors: why choose inefficient mitochondria? 131
Why mitochondria must fuse to maintain their genome integrity 129
OPA 1 mutations associated with dominant optic atrophy impair oxidative phosphorylation and mitochondrial fusion. 129
OPA1 Links Human Mitochondrial Genome Maintenance to mtDNA Replication and Distribution 126
The energetic failure caused by severe mutations in the mitochondrial genome is not rescued by Bcl-2 overexpression 125
The effects of idebenone on mitochondrial bioenergetics 122
Severe defect of complex I-dependent ATP synthesis shapes the mitochondria-driven path of apoptotic cell death in Leber’s Hereditary Optic Neuropathy. 120
Novel mutations in mitochondrial respiratory complexes and their functional relevance in thyroid oncocytoma. 118
Modelling ND subunits of complex I: Leber’s Hereditary Optic Neuropathy (LHON) pathogenic mutations and non-synonymous population variants in genotype-phenotype correlation 117
Cybrids with mtDNA mutations causing Leber’s hereditary optic neuropathy are sensitized to apoptotic death induced by a mitochondrial oxidative stress 114
OPA1 directly interacts with respiratory complexes and AIF. 113
null 109
null 109
Effect of bcl-2 on the oxidative phosphorylation efficiency of cells with defective respiratory complex I. 108
Oxidative phosphorylation dysfunction in fibroblasts bearing different pathological OPA1 mutations. 107
Functional genomics of thyroid oncocytoma 107
Impairment of mitochondrial fusion in dominant optic atrophy, a model for selective neurodegeneration 106
OPA3 IS AN INNER MITOCHONDRIAL MEMBRANE PROTEIN INVOLVED IN MITOCHONDRIAL DYNAMICS REGULATION 105
Mitochondrial Respiratory Supercomplexes in Physiology and Diseases 105
Cellular and mitochondrial determination of low molecular mass organic acids by LC-MS/MS 104
Organization of the respiratory supercomplexes in cells with defective complex III: Structural features and metabolic consequences 103
Functional investigation of the mitochondrial protein OPA3 102
Energetic efficiency and mitochondrial dynamics in fibroblasts derived from patients with optic neuropathies. 99
Molecular mechanisms of superoxide production by complex III: A bacterial versus human mitochondrial comparative case study. 98
Complex II phosphorylation is triggered by unbalanced redox homeostasis in cells lacking complex III 93
Respiratory Chain Function and Mitochondrial Dynamics in Leber's Hereditary Optic Neuropathy (LHON) and OPA1-Related Dominant Optic Atrophy (DOA) Fibroblasts. 84
Histamine activates phospholipase C in human airway epithelial cells via a phorbol ester-sensitive pathway 16
Totale 11.753
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Categoria #
all - tutte 31.143
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 31.143
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021838 0 0 0 0 0 69 27 92 93 82 59 416
2021/20221.632 128 55 97 88 137 85 56 113 57 208 358 250
2022/20231.825 199 306 101 222 91 131 53 107 301 48 150 116
2023/2024507 23 61 17 38 47 128 26 29 9 88 16 25
2024/20251.511 43 219 141 105 334 94 127 48 10 56 58 276
2025/20261.977 222 369 350 319 485 232 0 0 0 0 0 0
Totale 11.753