CRIS Current Research Information System

RUGOLO, MICHELA
 Distribuzione geografica
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Continente #
NA - Nord America 4.998
AS - Asia 3.855
EU - Europa 3.766
AF - Africa 337
SA - Sud America 172
OC - Oceania 19
Continente sconosciuto - Info sul continente non disponibili 6
Totale 13.153
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Nazione #
US - Stati Uniti d'America 4.947
CN - Cina 1.094
SG - Singapore 1.027
VN - Vietnam 906
GB - Regno Unito 866
IT - Italia 730
DE - Germania 459
SE - Svezia 447
UA - Ucraina 264
HK - Hong Kong 256
FR - Francia 217
IN - India 210
RU - Federazione Russa 202
BR - Brasile 127
CI - Costa d'Avorio 125
IE - Irlanda 115
FI - Finlandia 101
JP - Giappone 85
ZA - Sudafrica 83
TG - Togo 72
NL - Olanda 71
CH - Svizzera 65
KR - Corea 65
EE - Estonia 56
JO - Giordania 52
SC - Seychelles 39
BG - Bulgaria 31
CA - Canada 30
AR - Argentina 23
PH - Filippine 20
ES - Italia 19
PL - Polonia 19
AU - Australia 18
BD - Bangladesh 18
BE - Belgio 18
AT - Austria 17
ID - Indonesia 17
IQ - Iraq 16
MX - Messico 16
PK - Pakistan 15
BY - Bielorussia 11
GR - Grecia 10
IR - Iran 10
TW - Taiwan 10
SA - Arabia Saudita 9
TR - Turchia 9
CZ - Repubblica Ceca 8
TH - Thailandia 8
EC - Ecuador 7
HR - Croazia 7
LB - Libano 7
NG - Nigeria 6
RO - Romania 6
SK - Slovacchia (Repubblica Slovacca) 6
AE - Emirati Arabi Uniti 5
DK - Danimarca 5
UZ - Uzbekistan 5
CL - Cile 4
CO - Colombia 4
LT - Lituania 4
DZ - Algeria 3
MA - Marocco 3
PE - Perù 3
PT - Portogallo 3
SI - Slovenia 3
XK - ???statistics.table.value.countryCode.XK??? 3
DO - Repubblica Dominicana 2
EG - Egitto 2
EU - Europa 2
KG - Kirghizistan 2
NO - Norvegia 2
NP - Nepal 2
PY - Paraguay 2
A2 - ???statistics.table.value.countryCode.A2??? 1
BO - Bolivia 1
GE - Georgia 1
GN - Guinea 1
GT - Guatemala 1
IL - Israele 1
JM - Giamaica 1
KE - Kenya 1
LU - Lussemburgo 1
MD - Moldavia 1
MM - Myanmar 1
MN - Mongolia 1
MT - Malta 1
MY - Malesia 1
PG - Papua Nuova Guinea 1
PS - Palestinian Territory 1
RS - Serbia 1
SN - Senegal 1
TJ - Tagikistan 1
TN - Tunisia 1
TT - Trinidad e Tobago 1
VE - Venezuela 1
Totale 13.153
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Città #
Southend 700
Singapore 695
Ashburn 487
Fairfield 440
Chandler 435
Hong Kong 243
Santa Clara 243
Ann Arbor 242
Wilmington 221
Bologna 210
Woodbridge 206
San Jose 202
Houston 198
Seattle 190
Jacksonville 178
Ho Chi Minh City 164
Princeton 160
Cambridge 144
Hefei 143
Abidjan 125
Beijing 124
Dong Ket 118
Hanoi 118
Dublin 113
Boardman 106
Helsinki 91
Los Angeles 84
New York 80
Padova 74
Lomé 72
Westminster 72
Tokyo 71
Lauterbourg 66
Nanjing 59
Bern 57
Berlin 55
Amman 52
Jinan 46
Seoul 46
Saint Petersburg 43
Redmond 41
Turin 40
Council Bluffs 39
Dallas 39
Changsha 34
Milan 32
Mülheim 32
Medford 31
Buffalo 30
Guangzhou 30
Sofia 29
Shanghai 28
Tianjin 28
Hebei 27
San Diego 27
Shenyang 24
Haiphong 22
Johannesburg 22
Nanchang 21
Redondo Beach 21
Florence 20
Parma 20
Falls Church 19
Mahé 19
Redwood City 19
Glasgow 18
São Paulo 18
Brussels 17
Dearborn 17
Frankfurt am Main 17
Ningbo 17
Rome 17
Bengaluru 16
Da Nang 16
Jiaxing 16
Taizhou 16
Zhengzhou 16
Amsterdam 15
London 14
Munich 14
Norwalk 14
Phoenix 14
Shenzhen 14
Des Moines 13
Taiyuan 13
Verona 13
Kuban 12
Orem 12
Yubileyny 12
Chennai 11
Chicago 11
Dongjak-gu 11
Falkenstein 11
Fuzhou 11
Haikou 11
Hangzhou 11
Jakarta 11
Minsk 11
Modena 11
Warsaw 11
Totale 8.349
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Nome #
Eight human OPA1 isoforms, long and short: What are they for? 377
'Behr syndrome' with OPA1 compound heterozygote mutations 367
Coenzyme Q biosynthesis inhibition induces HIF-1α stabilization and metabolic switch toward glycolysis 310
Deciphering OPA1 mutations pathogenicity by combined analysis of human, mouse and yeast cell models 270
Different mtDNA mutations modify tumor progression in dependence of the degree of respiratory complex I impairment 265
Respiratory complex I is essential to induce a Warburg profile in mitochondria-defective tumor cells 257
A clinically complex form of dominant optic atrophy (OPA8) maps on chromosome 16. 242
An inherited mitochondrial DNA disruptive mutation shifts to homoplasmy in oncocytic tumor cells. 238
Apoptosis induced by staurosporine in ECV304 cells requires cell shrinkage and upregulation of Cl- conductance 225
The background of mitochondrial DNA haplogroup J increases the sensitivity of Leber's hereditary optic neuropathy cells to 2,5-hexanedione toxicity. 225
The antioxidant function of Bcl-2 preserves cytoskeletal stability of cells with defective respiratory complex I. 220
Alterations in the supramolecular interactions of respiratory chain complexes and enhanced superoxide production by the cytochrome b Y278C mutation which causes a multisystem disorder 217
Defective oxidative phosphorylation in thyroid oncocytic carcinoma is associated with pathogenic mitochondrial DNA mutations affecting complexes I and III 217
Drug repositioning as a therapeutic strategy for neurodegenerations associated with OPA1 mutations 214
Clonal expansion of mtDNA deletions: different disease models assessed by digital droplet PCR in single muscle cells. 207
Metabolomics hallmarks OPA1 variants correlating with their in-vitro phenotype and predicting clinical severity 206
pH difference across the outer mitochondrial membrane measured with a green fluorescent protein mutant 205
Syndromic parkinsonism and dementia associated with OPA1 missense mutations 203
Reactive Oxygen Species Produced by Mutated Mitochondrial Respiratory Chains of Entire Cells Monitored Using Modified Microelectrodes 202
Effect of energetic stress and the ceramide analogue C6-ceramide on thyroid oncocytoma cell lines. 196
OPA1 Isoforms in the Hierarchical Organization of Mitochondrial Functions 196
Disruptive mitochondrial DNA mutations in complex I subunits are markers of oncocytic phenotype in thyroid tumours. 194
The cytochrome B p.278Y>C mutation causative of a multisystem disorder enhances superoxide production and alters supramolecular interactions of respiratory chain complexes 192
Caspase-independent death of Leber's hereditary optic neuropathy cybrids is driven by energetic failure and mediated by AIF and Endonuclease G. 192
A Mutation Threshold Distinguishes the Antitumorigenic Effects of the Mitochondrial Gene MTND1, an Oncojanus Function 190
Fine-tuning of the respiratory complexes stability and supercomplexes assembly in cells defective of complex III 190
ATP depletion and caspase independent death of cybrids bearing Leber's Hereditary Optic neuropathy MTDNA mutations incubated in galactose medium. A model for endonuclease G-mediated apoptosis 185
Gamma rays induce a p53-independent mitochondrial biogenesis that is counter-regulated by HIF1α. 183
Effect of energetic stress and the ceramide analogue C6-ceramide on thyroid oncocytoma cell lines 182
A novel in-frame 18-bp microdeletion in MT-CYB causes a multisystem disorder with prominent exercise intolerance. 178
Cell death of fibroblasts derived from patients with Leber’s hereditary optic neuropathy mtDNA mutations 176
Rare mtDNA variants in Leber hereditary optic neuropathy families with recurrence of myoclonus. 176
OPA1: how much do we know to approach therapy? 176
Effect of energetic stress and the ceramide analogue C6-ceramide on thyroid oncocytoma cell lines 172
Green tea modulates a-1-adrenergic stimulated glucose transport in cultured cardiomyocytes via protein kinase C beta and delta isoforms 172
Green Tea Modulates Alpha-1-Adrenergic Stimulated Glucose Transport in Cultured Rat Cardiomyocytes 171
A cellular model for cancer progression: Role of mitochondrial mutations and metabolism 171
GLUCOSE TRANSPORT ACTIVATION IN HUMAN HEMATOPOIETIC CELLS M07e IS MODULATED BY CYTOSOLIC CALCIUM AND CALMODULIN 168
Evaluation of the energetic efficiency of cells derived from patients with dominant optic neuropathy (DOA). 161
The genetic and metabolic signature of oncocytic transformation implicates HIF1alpha destabilization 157
Bioenergetics shapes cellular death pathways in Leber’s hereditary optic neuropathy: a model of mitochondrial neurodegeneration 157
Determination of mitochondrial fusion in fibroblasts from dominant optic atrophy patients bearing the c.2708delttag OPA1 mutation 155
Biochimica 153
Protection against oxidant-induced apoptosis by exogenous glutathione in Leber Hereditary Optic Neuropathy cybrids. 153
Respiratory complex I dysfunction due to mitochondrial DNA mutations shifts the voltage threshold for opening of the permeability transition pore toward resting levels 153
OPA3, a new regulator of mitochondrial fission? 152
Mitochondria: Biogenesis and mitophagy balance in segregation and clonal expansion of mitochondrial DNA mutations 152
AIF and endonuclease G are involved in the caspase-indepenent death of cybrids with LHON mutations 149
Dominant optic neuropathy: analysis of the energetic efficiency and mitochondrial dynamics 148
OPA 1 mutations induce mitochondrial DNA instability and optic atrophy "plus" phenotypes 148
Mitochondrial DNA mutations in relation to cancer: the model of thyroid oncocytoma 146
Why mitochondria must fuse to maintain their genome integrity 146
OPA1 Links Human Mitochondrial Genome Maintenance to mtDNA Replication and Distribution 145
Learning from oncocytic tumors: why choose inefficient mitochondria? 144
OPA 1 mutations associated with dominant optic atrophy impair oxidative phosphorylation and mitochondrial fusion. 140
Cellular and mitochondrial determination of low molecular mass organic acids by LC-MS/MS 139
The effects of idebenone on mitochondrial bioenergetics 138
Novel mutations in mitochondrial respiratory complexes and their functional relevance in thyroid oncocytoma. 137
The energetic failure caused by severe mutations in the mitochondrial genome is not rescued by Bcl-2 overexpression 137
Modelling ND subunits of complex I: Leber’s Hereditary Optic Neuropathy (LHON) pathogenic mutations and non-synonymous population variants in genotype-phenotype correlation 131
Severe defect of complex I-dependent ATP synthesis shapes the mitochondria-driven path of apoptotic cell death in Leber’s Hereditary Optic Neuropathy. 130
Complex II phosphorylation is triggered by unbalanced redox homeostasis in cells lacking complex III 127
Effect of bcl-2 on the oxidative phosphorylation efficiency of cells with defective respiratory complex I. 125
OPA1 directly interacts with respiratory complexes and AIF. 124
OPA3 IS AN INNER MITOCHONDRIAL MEMBRANE PROTEIN INVOLVED IN MITOCHONDRIAL DYNAMICS REGULATION 124
Cybrids with mtDNA mutations causing Leber’s hereditary optic neuropathy are sensitized to apoptotic death induced by a mitochondrial oxidative stress 123
Impairment of mitochondrial fusion in dominant optic atrophy, a model for selective neurodegeneration 120
Oxidative phosphorylation dysfunction in fibroblasts bearing different pathological OPA1 mutations. 120
Mitochondrial Respiratory Supercomplexes in Physiology and Diseases 120
Organization of the respiratory supercomplexes in cells with defective complex III: Structural features and metabolic consequences 120
Functional genomics of thyroid oncocytoma 118
Functional investigation of the mitochondrial protein OPA3 118
Molecular mechanisms of superoxide production by complex III: A bacterial versus human mitochondrial comparative case study. 109
null 109
null 109
Energetic efficiency and mitochondrial dynamics in fibroblasts derived from patients with optic neuropathies. 107
Respiratory Chain Function and Mitochondrial Dynamics in Leber's Hereditary Optic Neuropathy (LHON) and OPA1-Related Dominant Optic Atrophy (DOA) Fibroblasts. 96
Histamine activates phospholipase C in human airway epithelial cells via a phorbol ester-sensitive pathway 26
Totale 13.393
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Categoria #
all - tutte 33.755
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 33.755
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021557 0 0 0 0 0 0 0 0 0 82 59 416
2021/20221.632 128 55 97 88 137 85 56 113 57 208 358 250
2022/20231.825 199 306 101 222 91 131 53 107 301 48 150 116
2023/2024507 23 61 17 38 47 128 26 29 9 88 16 25
2024/20251.511 43 219 141 105 334 94 127 48 10 56 58 276
2025/20263.617 222 369 350 319 485 278 500 157 686 251 0 0
Totale 13.393