CRIS Current Research Information System

RUGOLO, MICHELA
 Distribuzione geografica
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Continente #
NA - Nord America 3.729
EU - Europa 3.075
AS - Asia 997
AF - Africa 188
OC - Oceania 5
SA - Sud America 4
Continente sconosciuto - Info sul continente non disponibili 3
Totale 8.001
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Nazione #
US - Stati Uniti d'America 3.717
GB - Regno Unito 785
IT - Italia 580
SE - Svezia 444
DE - Germania 403
CN - Cina 379
VN - Vietnam 373
UA - Ucraina 260
IN - India 151
FR - Francia 124
IE - Irlanda 114
RU - Federazione Russa 114
TG - Togo 72
CH - Svizzera 63
EE - Estonia 56
ZA - Sudafrica 55
JO - Giordania 50
CI - Costa d'Avorio 35
BG - Bulgaria 30
SC - Seychelles 21
BE - Belgio 18
FI - Finlandia 16
JP - Giappone 13
CA - Canada 12
NL - Olanda 12
GR - Grecia 10
IR - Iran 9
AT - Austria 8
HK - Hong Kong 6
HR - Croazia 6
SK - Slovacchia (Repubblica Slovacca) 6
AU - Australia 5
DK - Danimarca 5
LB - Libano 5
NG - Nigeria 5
RO - Romania 5
ES - Italia 4
BR - Brasile 3
CZ - Repubblica Ceca 3
SG - Singapore 3
AE - Emirati Arabi Uniti 2
EU - Europa 2
NO - Norvegia 2
PK - Pakistan 2
PT - Portogallo 2
SI - Slovenia 2
A2 - ???statistics.table.value.countryCode.A2??? 1
BD - Bangladesh 1
KR - Corea 1
LU - Lussemburgo 1
MD - Moldavia 1
MN - Mongolia 1
PE - Perù 1
PL - Polonia 1
TR - Turchia 1
Totale 8.001
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Città #
Southend 700
Fairfield 440
Chandler 435
Ashburn 333
Ann Arbor 242
Wilmington 221
Woodbridge 206
Houston 193
Seattle 184
Bologna 178
Jacksonville 176
Princeton 160
Cambridge 137
Dong Ket 118
Dublin 112
Padova 74
Lomé 72
Westminster 72
New York 60
Bern 57
Nanjing 56
Berlin 55
Amman 50
Jinan 43
Saint Petersburg 43
Redmond 41
Turin 40
Abidjan 35
Mülheim 32
Medford 31
Sofia 29
Changsha 28
Hebei 27
San Diego 27
Beijing 24
Milan 24
Shenyang 24
Boardman 22
Nanchang 21
Florence 20
Falls Church 19
Mahé 19
Redwood City 19
Tianjin 18
Brussels 17
Dearborn 17
Jiaxing 15
Norwalk 14
Taizhou 14
Des Moines 13
Helsinki 13
Los Angeles 13
Tokyo 13
Verona 13
Kuban 12
Zhengzhou 12
Haikou 11
Ningbo 11
Rome 11
Argelato 10
Fuzhou 10
Mountain View 10
Taiyuan 10
Guangzhou 9
Olalla 9
Pune 9
Hangzhou 8
London 7
Modena 7
Paris 7
Bratislava 6
Bremen 6
Lanzhou 6
Abeokuta 5
Bühl 5
Fremont 5
Groningen 5
Hefei 5
Lynchburg 5
Monmouth Junction 5
Shanghai 5
Amsterdam 4
Chicago 4
Costa Mesa 4
Forlì 4
Frankfurt Am Main 4
Hong Kong 4
Lausanne 4
Napoli 4
Phoenix 4
San Venanzo 4
Toronto 4
Ancona 3
Andover 3
Atlanta 3
Borgonovo Val Tidone 3
Bovolone 3
Ferrara 3
Hanover 3
Kunming 3
Totale 5.338
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Nome #
A clinically complex form of dominant optic atrophy (OPA8) maps on chromosome 16. 188
Different mtDNA mutations modify tumor progression in dependence of the degree of respiratory complex I impairment 185
Coenzyme Q biosynthesis inhibition induces HIF-1α stabilization and metabolic switch toward glycolysis 184
'Behr syndrome' with OPA1 compound heterozygote mutations 172
An inherited mitochondrial DNA disruptive mutation shifts to homoplasmy in oncocytic tumor cells. 169
Respiratory complex I is essential to induce a Warburg profile in mitochondria-defective tumor cells 160
Alterations in the supramolecular interactions of respiratory chain complexes and enhanced superoxide production by the cytochrome b Y278C mutation which causes a multisystem disorder 158
The antioxidant function of Bcl-2 preserves cytoskeletal stability of cells with defective respiratory complex I. 153
The background of mitochondrial DNA haplogroup J increases the sensitivity of Leber's hereditary optic neuropathy cells to 2,5-hexanedione toxicity. 153
Defective oxidative phosphorylation in thyroid oncocytic carcinoma is associated with pathogenic mitochondrial DNA mutations affecting complexes I and III 151
Apoptosis induced by staurosporine in ECV304 cells requires cell shrinkage and upregulation of Cl- conductance 145
Deciphering OPA1 mutations pathogenicity by combined analysis of human, mouse and yeast cell models 145
Clonal expansion of mtDNA deletions: different disease models assessed by digital droplet PCR in single muscle cells. 145
Caspase-independent death of Leber's hereditary optic neuropathy cybrids is driven by energetic failure and mediated by AIF and Endonuclease G. 137
Eight human OPA1 isoforms, long and short: What are they for? 136
pH difference across the outer mitochondrial membrane measured with a green fluorescent protein mutant 134
A cellular model for cancer progression: Role of mitochondrial mutations and metabolism 132
Reactive Oxygen Species Produced by Mutated Mitochondrial Respiratory Chains of Entire Cells Monitored Using Modified Microelectrodes 130
Cell death of fibroblasts derived from patients with Leber’s hereditary optic neuropathy mtDNA mutations 129
ATP depletion and caspase independent death of cybrids bearing Leber's Hereditary Optic neuropathy MTDNA mutations incubated in galactose medium. A model for endonuclease G-mediated apoptosis 125
A Mutation Threshold Distinguishes the Antitumorigenic Effects of the Mitochondrial Gene MTND1, an Oncojanus Function 123
OPA1 Isoforms in the Hierarchical Organization of Mitochondrial Functions 121
The cytochrome B p.278Y>C mutation causative of a multisystem disorder enhances superoxide production and alters supramolecular interactions of respiratory chain complexes 120
Gamma rays induce a p53-independent mitochondrial biogenesis that is counter-regulated by HIF1α. 116
GLUCOSE TRANSPORT ACTIVATION IN HUMAN HEMATOPOIETIC CELLS M07e IS MODULATED BY CYTOSOLIC CALCIUM AND CALMODULIN 116
Bioenergetics shapes cellular death pathways in Leber’s hereditary optic neuropathy: a model of mitochondrial neurodegeneration 115
Effect of energetic stress and the ceramide analogue C6-ceramide on thyroid oncocytoma cell lines. 114
AIF and endonuclease G are involved in the caspase-indepenent death of cybrids with LHON mutations 113
The genetic and metabolic signature of oncocytic transformation implicates HIF1alpha destabilization 111
OPA1: how much do we know to approach therapy? 111
Disruptive mitochondrial DNA mutations in complex I subunits are markers of oncocytic phenotype in thyroid tumours. 111
null 109
null 109
Effect of energetic stress and the ceramide analogue C6-ceramide on thyroid oncocytoma cell lines 107
Syndromic parkinsonism and dementia associated with OPA1 missense mutations 107
Protection against oxidant-induced apoptosis by exogenous glutathione in Leber Hereditary Optic Neuropathy cybrids. 106
Rare mtDNA variants in Leber hereditary optic neuropathy families with recurrence of myoclonus. 104
OPA 1 mutations induce mitochondrial DNA instability and optic atrophy "plus" phenotypes 104
Green tea modulates a-1-adrenergic stimulated glucose transport in cultured cardiomyocytes via protein kinase C beta and delta isoforms 104
Evaluation of the energetic efficiency of cells derived from patients with dominant optic neuropathy (DOA). 103
Green Tea Modulates Alpha-1-Adrenergic Stimulated Glucose Transport in Cultured Rat Cardiomyocytes 103
Learning from oncocytic tumors: why choose inefficient mitochondria? 103
Biochimica 102
Respiratory complex I dysfunction due to mitochondrial DNA mutations shifts the voltage threshold for opening of the permeability transition pore toward resting levels 102
Metabolomics hallmarks OPA1 variants correlating with their in-vitro phenotype and predicting clinical severity 101
Determination of mitochondrial fusion in fibroblasts from dominant optic atrophy patients bearing the c.2708delttag OPA1 mutation 100
Drug repositioning as a therapeutic strategy for neurodegenerations associated with OPA1 mutations 99
Mitochondria: Biogenesis and mitophagy balance in segregation and clonal expansion of mitochondrial DNA mutations 97
Effect of energetic stress and the ceramide analogue C6-ceramide on thyroid oncocytoma cell lines 94
A novel in-frame 18-bp microdeletion in MT-CYB causes a multisystem disorder with prominent exercise intolerance. 93
The effects of idebenone on mitochondrial bioenergetics 91
OPA3, a new regulator of mitochondrial fission? 91
Why mitochondria must fuse to maintain their genome integrity 88
OPA 1 mutations associated with dominant optic atrophy impair oxidative phosphorylation and mitochondrial fusion. 88
Dominant optic neuropathy: analysis of the energetic efficiency and mitochondrial dynamics 87
OPA1 Links Human Mitochondrial Genome Maintenance to mtDNA Replication and Distribution 87
Mitochondrial DNA mutations in relation to cancer: the model of thyroid oncocytoma 86
Cybrids with mtDNA mutations causing Leber’s hereditary optic neuropathy are sensitized to apoptotic death induced by a mitochondrial oxidative stress 85
Severe defect of complex I-dependent ATP synthesis shapes the mitochondria-driven path of apoptotic cell death in Leber’s Hereditary Optic Neuropathy. 80
Modelling ND subunits of complex I: Leber’s Hereditary Optic Neuropathy (LHON) pathogenic mutations and non-synonymous population variants in genotype-phenotype correlation 79
The energetic failure caused by severe mutations in the mitochondrial genome is not rescued by Bcl-2 overexpression 77
Fine-tuning of the respiratory complexes stability and supercomplexes assembly in cells defective of complex III 76
Functional genomics of thyroid oncocytoma 75
Molecular mechanisms of superoxide production by complex III: A bacterial versus human mitochondrial comparative case study. 72
OPA1 directly interacts with respiratory complexes and AIF. 71
Effect of bcl-2 on the oxidative phosphorylation efficiency of cells with defective respiratory complex I. 71
Energetic efficiency and mitochondrial dynamics in fibroblasts derived from patients with optic neuropathies. 70
Mitochondrial Respiratory Supercomplexes in Physiology and Diseases 70
Novel mutations in mitochondrial respiratory complexes and their functional relevance in thyroid oncocytoma. 69
Oxidative phosphorylation dysfunction in fibroblasts bearing different pathological OPA1 mutations. 68
Functional investigation of the mitochondrial protein OPA3 62
Impairment of mitochondrial fusion in dominant optic atrophy, a model for selective neurodegeneration 61
OPA3 IS AN INNER MITOCHONDRIAL MEMBRANE PROTEIN INVOLVED IN MITOCHONDRIAL DYNAMICS REGULATION 61
Respiratory Chain Function and Mitochondrial Dynamics in Leber's Hereditary Optic Neuropathy (LHON) and OPA1-Related Dominant Optic Atrophy (DOA) Fibroblasts. 60
Cellular and mitochondrial determination of low molecular mass organic acids by LC-MS/MS 54
Organization of the respiratory supercomplexes in cells with defective complex III: Structural features and metabolic consequences 49
Complex II phosphorylation is triggered by unbalanced redox homeostasis in cells lacking complex III 46
Histamine activates phospholipase C in human airway epithelial cells via a phorbol ester-sensitive pathway 1
Totale 8.224
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Categoria #
all - tutte 18.083
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 18.083
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/2019181 0 0 0 0 0 0 0 0 0 90 25 66
2019/20202.138 316 51 41 114 175 197 217 297 304 147 107 172
2020/20211.276 243 87 26 61 21 69 27 92 93 82 59 416
2021/20221.632 128 55 97 88 137 85 56 113 57 208 358 250
2022/20231.825 199 306 101 222 91 131 53 107 301 48 150 116
2023/2024466 23 61 17 38 47 128 26 29 9 88 0 0
Totale 8.224