RUGOLO, MICHELA
RUGOLO, MICHELA
DIPARTIMENTO DI FARMACIA E BIOTECNOLOGIE
Coenzyme Q biosynthesis inhibition induces HIF-1α stabilization and metabolic switch toward glycolysis
2021 Liparulo, Irene; Bergamini, Christian; Bortolus, Marco; Calonghi, Natalia; Gasparre, Giuseppe; Kurelac, Ivana; Masin, Luca; Rizzardi, Nicola; Rugolo, Michela; Wang, Wenping; Aleo, Serena J; Kiwan, Alisar; Torri, Cristian; Zanna, Claudia; Fato, Romana
Organization of the respiratory supercomplexes in cells with defective complex III: Structural features and metabolic consequences
2021 Rugolo M.; Zanna C.; Ghelli A.M.
Drug repositioning as a therapeutic strategy for neurodegenerations associated with OPA1 mutations
2020 Aleo, Serena J; Del Dotto, Valentina; Fogazza, Mario; Maresca, Alessandra; Lodi, Tiziana; Goffrini, Paola; Ghelli, Anna; Rugolo, Michela; Carelli, Valerio; Baruffini, Enrico; Zanna, Claudia
Fine-tuning of the respiratory complexes stability and supercomplexes assembly in cells defective of complex III
2020 Tropeano C.V.; Aleo S.J.; Zanna C.; Roberti M.; Scandiffio L.; Loguercio Polosa P.; Fiori J.; Porru E.; Roda A.; Carelli V.; Steimle S.; Daldal F.; Rugolo M.; Ghelli A.
Metabolomics hallmarks OPA1 variants correlating with their in-vitro phenotype and predicting clinical severity
2020 Barca, Juan Manuel Chao; Fogazza, Mario; Rugolo, Michela; Chupin, Stéphanie; Del Dotto, Valentina; Ghelli, Anna Maria; Carelli, Valerio; Simard, Gilles; Procaccio, Vincent; Bonneau, Dominique; Lenaers, Guy; Reynier, Pascal; Zanna, Claudia
Reactive Oxygen Species Produced by Mutated Mitochondrial Respiratory Chains of Entire Cells Monitored Using Modified Microelectrodes
2019 Malferrari, Marco; Ghelli, Anna*; Roggiani, Francesco; Valenti, Giovanni; Paolucci, Francesco; Rugolo, Michela; Rapino, Stefania
Cellular and mitochondrial determination of low molecular mass organic acids by LC-MS/MS
2018 Fiori, Jessica; Amadesi, Elisa; Fanelli, Flaminia; Tropeano, Concetta Valentina; Rugolo, Michela; Gotti, Roberto
Clonal expansion of mtDNA deletions: different disease models assessed by digital droplet PCR in single muscle cells.
2018 Trifunov S., Pyle A., Valentino ML., Liguori R., Yu-Wai-Man P., Burté F., Duff J., Kleinle S., Diebold I., Rugolo M., Horvath R., Carelli V.
Complex II phosphorylation is triggered by unbalanced redox homeostasis in cells lacking complex III
2018 Tropeano, Concetta Valentina; Fiori, Jessica; Carelli, Valerio; Caporali, Leonardo; Daldal, Fevzi; Ghelli, Anna Maria; Rugolo, Michela
Deciphering OPA1 mutations pathogenicity by combined analysis of human, mouse and yeast cell models
2018 Del Dotto, Valentina; Fogazza, Mario; Musiani, Francesco; Maresca, Alessandra; Aleo, Serena J.; Caporali, Leonardo; La Morgia, Chiara; Nolli, Cecilia; Lodi, Tiziana; Goffrini, Paola; Chan, David; Carelli, Valerio; Rugolo, Michela; Baruffini, Enrico; Zanna, Claudia*
Eight human OPA1 isoforms, long and short: What are they for?
2018 Del Dotto, Valentina; Fogazza, Mario; Carelli, Valerio; Rugolo, Michela; Zanna, Claudia
OPA1: how much do we know to approach therapy?
2018 Del Dotto, Valentina; Fogazza, Mario; Lenaers, Guy; Rugolo, Michela; Carelli, Valerio; Zanna, Claudia
OPA1 Isoforms in the Hierarchical Organization of Mitochondrial Functions
2017 Del Dotto, Valentina; Mishra, Prashant; Vidoni, Sara; Fogazza, Mario; Maresca, Alessandra; Caporali, Leonardo; Mccaffery, J Michael; Cappelletti, Martina; Baruffini, Enrico; Lenaers, Guy; Chan, David; Rugolo, Michela; Carelli, Valerio; Zanna, Claudia
'Behr syndrome' with OPA1 compound heterozygote mutations
2015 Carelli, Valerio; Sabatelli, Mario; Carrozzo, Rosalba; Rizza, Teresa; Schimpf, Simone; Wissinger, Bernd; Zanna, Claudia; Rugolo, Michela; La Morgia, Chiara; Caporali, Leonardo; Carbonelli, Michele; Barboni, Piero; Tonon, Caterina; Lodi, Raffaele; Bertini, Enrico
Mitochondria: Biogenesis and mitophagy balance in segregation and clonal expansion of mitochondrial DNA mutations
2015 Valerio, Carelli; Alessandra, Maresca; Leonardo, Caporali; Selena, Trifunov; Claudia, Zanna; Michela, Rugolo
Mitochondrial Respiratory Supercomplexes in Physiology and Diseases
2015 Ghelli, Anna Maria; Valentina C. Tropeano; Rugolo, Michela
Syndromic parkinsonism and dementia associated with OPA1 missense mutations
2015 Carelli, V.; Musumeci, O.; Caporali, L.; Zanna, C.; La Morgia, C.; Del Dotto, V.; Porcelli, A.M.; Rugolo, M.; Valentino, M.L.; Iommarini, L.; Maresca, A.; Barboni, P.; Carbonelli, M.; Trombetta, C.; Valente, E.M.; Patergnani, S.; Giorgi, C.; Pinton, P.; Rizzo, G.; Tonon, C.; Lodi, R.; Avoni, P.; Liguori, R.; Baruzzi, A.; Toscano, A.; Zeviani, M.
A novel in-frame 18-bp microdeletion in MT-CYB causes a multisystem disorder with prominent exercise intolerance.
2014 Carossa V;Ghelli A;Tropeano CV;Valentino ML;Iommarini L;Maresca A;Caporali L;Morgia CL;Liguori R;Barboni P;Carbonelli M;Rizzo G;Tonon C;Lodi R;Martinuzzi A;Nardo VD;Rugolo M;Ferretti L;Gandini F;Pala M;Achilli A;Olivieri A;Torroni A;Carelli V
Different mtDNA mutations modify tumor progression in dependence of the degree of respiratory complex I impairment
2014 L. Iommarini;I. Kurelac;M. Capristo;M. A. Calvaruso;V. Giorgio;C. Bergamini;A. Ghelli;P. Nanni;C. De Giovanni;V. Carelli;R. Fato;P. L. Lollini;M. Rugolo;G. Gasparre;A. M. Porcelli
Gamma rays induce a p53-independent mitochondrial biogenesis that is counter-regulated by HIF1α.
2013 Bartoletti-Stella A;Mariani E;Kurelac I;Maresca A;Caratozzolo MF;Iommarini L;Carelli V;Eusebi LH;Guido A;Cenacchi G;Fuccio L;Rugolo M;Tullo A;Porcelli AM;Gasparre G
| Titolo | Autore(i) | Anno | Periodico | Editore | Tipo | File |
|---|---|---|---|---|---|---|
| Coenzyme Q biosynthesis inhibition induces HIF-1α stabilization and metabolic switch toward glycolysis | Liparulo, Irene; Bergamini, Christian; Bortolus, Marco; Calonghi, Natalia; Gasparre, Giuseppe; Ku...relac, Ivana; Masin, Luca; Rizzardi, Nicola; Rugolo, Michela; Wang, Wenping; Aleo, Serena J; Kiwan, Alisar; Torri, Cristian; Zanna, Claudia; Fato, Romana | 2021-01-01 | THE FEBS JOURNAL | - | 1.01 Articolo in rivista | - |
| Organization of the respiratory supercomplexes in cells with defective complex III: Structural features and metabolic consequences | Rugolo M.; Zanna C.; Ghelli A.M. | 2021-01-01 | LIFE | - | 1.01 Articolo in rivista | 2021 - Rugolo et al - Review CIII and SCs.pdf |
| Drug repositioning as a therapeutic strategy for neurodegenerations associated with OPA1 mutations | Aleo, Serena J; Del Dotto, Valentina; Fogazza, Mario; Maresca, Alessandra; Lodi, Tiziana; Goffrin...i, Paola; Ghelli, Anna; Rugolo, Michela; Carelli, Valerio; Baruffini, Enrico; Zanna, Claudia | 2020-01-01 | HUMAN MOLECULAR GENETICS | - | 1.01 Articolo in rivista | 2021 - Aleo et al HMG.pdf; supplementary_material_19-10-20_ddaa244.docx |
| Fine-tuning of the respiratory complexes stability and supercomplexes assembly in cells defective of complex III | Tropeano C.V.; Aleo S.J.; Zanna C.; Roberti M.; Scandiffio L.; Loguercio Polosa P.; Fiori J.; Por...ru E.; Roda A.; Carelli V.; Steimle S.; Daldal F.; Rugolo M.; Ghelli A. | 2020-01-01 | BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS | - | 1.01 Articolo in rivista | Fine-tuning of the respiratory complexes stability and supercomplexes assembly in cells defective of complex III.pdf |
| Metabolomics hallmarks OPA1 variants correlating with their in-vitro phenotype and predicting clinical severity | Barca, Juan Manuel Chao; Fogazza, Mario; Rugolo, Michela; Chupin, Stéphanie; Del Dotto, Valentina...; Ghelli, Anna Maria; Carelli, Valerio; Simard, Gilles; Procaccio, Vincent; Bonneau, Dominique; Lenaers, Guy; Reynier, Pascal; Zanna, Claudia | 2020-01-01 | HUMAN MOLECULAR GENETICS ONLINE | - | 1.01 Articolo in rivista | Metabolomics hallmarks OPA1 variants correlating with their in-vitro phenotype and predicting clinical severity.pdf |
| Reactive Oxygen Species Produced by Mutated Mitochondrial Respiratory Chains of Entire Cells Monitored Using Modified Microelectrodes | Malferrari, Marco; Ghelli, Anna*; Roggiani, Francesco; Valenti, Giovanni; Paolucci, Francesco; Ru...golo, Michela; Rapino, Stefania | 2019-01-01 | CHEMELECTROCHEM | - | 1.01 Articolo in rivista | - |
| Cellular and mitochondrial determination of low molecular mass organic acids by LC-MS/MS | Fiori, Jessica; Amadesi, Elisa; Fanelli, Flaminia; Tropeano, Concetta Valentina; Rugolo, Michela;... Gotti, Roberto | 2018-01-01 | JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS | - | 1.01 Articolo in rivista | - |
| Clonal expansion of mtDNA deletions: different disease models assessed by digital droplet PCR in single muscle cells. |
Trifunov S., Pyle A., Valentino ML., Liguori R., Yu-Wai-Man P., Burté F., Duff J., Kleinle S., Di...ebold I., Rugolo M., Horvath R., Carelli V. |
2018-01-01 | SCIENTIFIC REPORTS | - | 1.01 Articolo in rivista | Trifunov SciRep 2018ms.pdf |
| Complex II phosphorylation is triggered by unbalanced redox homeostasis in cells lacking complex III | Tropeano, Concetta Valentina; Fiori, Jessica; Carelli, Valerio; Caporali, Leonardo; Daldal, Fevzi...; Ghelli, Anna Maria; Rugolo, Michela | 2018-01-01 | BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS | - | 1.01 Articolo in rivista | - |
| Deciphering OPA1 mutations pathogenicity by combined analysis of human, mouse and yeast cell models | Del Dotto, Valentina; Fogazza, Mario; Musiani, Francesco; Maresca, Alessandra; Aleo, Serena J.; C...aporali, Leonardo; La Morgia, Chiara; Nolli, Cecilia; Lodi, Tiziana; Goffrini, Paola; Chan, David; Carelli, Valerio; Rugolo, Michela; Baruffini, Enrico; Zanna, Claudia* | 2018-01-01 | BIOCHIMICA ET BIOPHYSICA ACTA. MOLECULAR BASIS OF DISEASE | - | 1.01 Articolo in rivista | 56_2018_DelDotto_BBAMolBasisDisease.pdf |
| Eight human OPA1 isoforms, long and short: What are they for? | Del Dotto, Valentina; Fogazza, Mario; Carelli, Valerio; Rugolo, Michela; Zanna, Claudia | 2018-01-01 | BIOCHIMICA ET BIOPHYSICA ACTA | - | 1.01 Articolo in rivista | EightHumanOPA1_DelDotto_def.pdf |
| OPA1: how much do we know to approach therapy? | Del Dotto, Valentina; Fogazza, Mario; Lenaers, Guy; Rugolo, Michela; Carelli, Valerio; Zanna, Cla...udia | 2018-01-01 | PHARMACOLOGICAL RESEARCH | - | 1.01 Articolo in rivista | - |
| OPA1 Isoforms in the Hierarchical Organization of Mitochondrial Functions | Del Dotto, Valentina; Mishra, Prashant; Vidoni, Sara; Fogazza, Mario; Maresca, Alessandra; Capora...li, Leonardo; Mccaffery, J Michael; Cappelletti, Martina; Baruffini, Enrico; Lenaers, Guy; Chan, David; Rugolo, Michela; Carelli, Valerio; Zanna, Claudia | 2017-01-01 | CELL REPORTS | - | 1.01 Articolo in rivista | 1-s2.0-S2211124717307465-main.pdf |
| 'Behr syndrome' with OPA1 compound heterozygote mutations | Carelli, Valerio; Sabatelli, Mario; Carrozzo, Rosalba; Rizza, Teresa; Schimpf, Simone; Wissinger,... Bernd; Zanna, Claudia; Rugolo, Michela; La Morgia, Chiara; Caporali, Leonardo; Carbonelli, Michele; Barboni, Piero; Tonon, Caterina; Lodi, Raffaele; Bertini, Enrico | 2015-01-01 | BRAIN | - | 1.01 Articolo in rivista | - |
| Mitochondria: Biogenesis and mitophagy balance in segregation and clonal expansion of mitochondrial DNA mutations | Valerio, Carelli; Alessandra, Maresca; Leonardo, Caporali; Selena, Trifunov; Claudia, Zanna; Mich...ela, Rugolo | 2015-01-01 | THE INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY | - | 1.01 Articolo in rivista | - |
| Mitochondrial Respiratory Supercomplexes in Physiology and Diseases | Ghelli, Anna Maria; Valentina C. Tropeano; Rugolo, Michela | 2015-01-01 | - | Ricardo O. Louro; Irene Diaz-Moreno | 2.01 Capitolo / saggio in libro | - |
| Syndromic parkinsonism and dementia associated with OPA1 missense mutations | Carelli, V.; Musumeci, O.; Caporali, L.; Zanna, C.; La Morgia, C.; Del Dotto, V.; Porcelli, A.M.;... Rugolo, M.; Valentino, M.L.; Iommarini, L.; Maresca, A.; Barboni, P.; Carbonelli, M.; Trombetta, C.; Valente, E.M.; Patergnani, S.; Giorgi, C.; Pinton, P.; Rizzo, G.; Tonon, C.; Lodi, R.; Avoni, P.; Liguori, R.; Baruzzi, A.; Toscano, A.; Zeviani, M. | 2015-01-01 | ANNALS OF NEUROLOGY | - | 1.01 Articolo in rivista | ana.24410.pdf |
| A novel in-frame 18-bp microdeletion in MT-CYB causes a multisystem disorder with prominent exercise intolerance. | Carossa V;Ghelli A;Tropeano CV;Valentino ML;Iommarini L;Maresca A;Caporali L;Morgia CL;Liguori R;...Barboni P;Carbonelli M;Rizzo G;Tonon C;Lodi R;Martinuzzi A;Nardo VD;Rugolo M;Ferretti L;Gandini F;Pala M;Achilli A;Olivieri A;Torroni A;Carelli V | 2014-01-01 | HUMAN MUTATION | - | 1.01 Articolo in rivista | - |
| Different mtDNA mutations modify tumor progression in dependence of the degree of respiratory complex I impairment | L. Iommarini;I. Kurelac;M. Capristo;M. A. Calvaruso;V. Giorgio;C. Bergamini;A. Ghelli;P. Nanni;C.... De Giovanni;V. Carelli;R. Fato;P. L. Lollini;M. Rugolo;G. Gasparre;A. M. Porcelli | 2014-01-01 | HUMAN MOLECULAR GENETICS | - | 1.01 Articolo in rivista | - |
| Gamma rays induce a p53-independent mitochondrial biogenesis that is counter-regulated by HIF1α. | Bartoletti-Stella A;Mariani E;Kurelac I;Maresca A;Caratozzolo MF;Iommarini L;Carelli V;Eusebi LH;...Guido A;Cenacchi G;Fuccio L;Rugolo M;Tullo A;Porcelli AM;Gasparre G | 2013-01-01 | CELL DEATH & DISEASE | - | 1.01 Articolo in rivista | cddis2013187.pdf |