RUGOLO, MICHELA
RUGOLO, MICHELA
DIPARTIMENTO DI FARMACIA E BIOTECNOLOGIE
'Behr syndrome' with OPA1 compound heterozygote mutations
2015 Carelli, Valerio; Sabatelli, Mario; Carrozzo, Rosalba; Rizza, Teresa; Schimpf, Simone; Wissinger, Bernd; Zanna, Claudia; Rugolo, Michela; La Morgia, Chiara; Caporali, Leonardo; Carbonelli, Michele; Barboni, Piero; Tonon, Caterina; Lodi, Raffaele; Bertini, Enrico
A cellular model for cancer progression: Role of mitochondrial mutations and metabolism
2010 G. Romeo; G. Gasparre; A.M. Porcelli; M. Rugolo
A clinically complex form of dominant optic atrophy (OPA8) maps on chromosome 16.
2011 Carelli V.; Schimpf S.; Fuhrmann N.; Valentino M.L.; Zanna C.; Iommarini L.; Papke M.; Schaich S.; Tippmann S.; Baumann B.; Barboni P.; Longanesi L.; Rugolo M.; Ghelli A.; Alavi M.V.; Youle R.J.; Bucchi L.; Carroccia R.; Giannoccaro M.P.; Tonon C.; Lodi R.; Cenacchi G.; Montagna P.; Liguori R.; Wissinger B.
A Mutation Threshold Distinguishes the Antitumorigenic Effects of the Mitochondrial Gene MTND1, an Oncojanus Function
2011 Gasparre G; Kurelac I; Capristo M; Iommarini L; Ghelli A; Ceccarelli C; Nicoletti G; Nanni P; De Giovanni C; Scotlandi K; Betts CM; Carelli V; Lollini PL; Romeo G; Rugolo M; Porcelli AM
A novel in-frame 18-bp microdeletion in MT-CYB causes a multisystem disorder with prominent exercise intolerance.
2014 Carossa V;Ghelli A;Tropeano CV;Valentino ML;Iommarini L;Maresca A;Caporali L;Morgia CL;Liguori R;Barboni P;Carbonelli M;Rizzo G;Tonon C;Lodi R;Martinuzzi A;Nardo VD;Rugolo M;Ferretti L;Gandini F;Pala M;Achilli A;Olivieri A;Torroni A;Carelli V
AIF and endonuclease G are involved in the caspase-indepenent death of cybrids with LHON mutations
2004 A.M.Porcelli; C. Zanna; A. Montanaro; V.Carelli; A.Ghelli; M.Rugolo
Alterations in the supramolecular interactions of respiratory chain complexes and enhanced superoxide production by the cytochrome b Y278C mutation which causes a multisystem disorder
2012 Ghelli A.; Tropeano C.V.; Calvaruso M.A.; Marchesini A.; Iommarini L.; Porcelli A.M.; Zanna C.; Gasparre G.; Kurelac I.; De Nardo V.; Martinuzzi A.; Vissing J.; Selamoglu N.; Daldal F.; Rugolo M.
An inherited mitochondrial DNA disruptive mutation shifts to homoplasmy in oncocytic tumor cells.
2009 G.Gasparre; L. Iommarini; A.M. Porcelli; M. Lang; G.G. Ferri; I.Kurelac; E. Mariani; L.F. Pennisi; E. Pasquini; G. Pasquinelli; A. Ghelli; E. Bonora; C. Ceccarelli; M. Rugolo; N. Salfi; G. Romeo; V. Carelli.
Apoptosis induced by staurosporine in ECV304 cells requires cell shrinkage and upregulation of Cl- conductance
2004 A.M. PORCELLI; A. GHELLI; C. ZANNA; P. VALENTE; S. FERRONI; M. RUGOLO
ATP depletion and caspase independent death of cybrids bearing Leber's Hereditary Optic neuropathy MTDNA mutations incubated in galactose medium. A model for endonuclease G-mediated apoptosis
2004 A. Ghelli; C. Zanna; A.M. Porcelli; V. Carelli; M. Rugolo
Biochimica
2007 Ascenzi P.; Contestabile R.; Di Salvo M.L.; Faraone Mennella M.R.; Fusi P.; Lenaz G.; Pascarella S.; Quesada P.M.; Rugolo M.; Sorrentino S.; Tortora P.; Turina P.
Bioenergetics shapes cellular death pathways in Leber’s hereditary optic neuropathy: a model of mitochondrial neurodegeneration
2004 CARELLI V; RUGOLO M; SGARBI G; GHELLI A; ZANNA C; BARACCA A; LENAZ G; NAPOLI E; MARTINUZZI A; SOLAINI G.
Caspase-independent death of Leber's hereditary optic neuropathy cybrids is driven by energetic failure and mediated by AIF and Endonuclease G.
2005 ZANNA C.; GHELLI A.; PORCELLI AM.; MARTINUZZI A.; Carelli V.; RUGOLO M.
Cell death of fibroblasts derived from patients with Leber’s hereditary optic neuropathy mtDNA mutations
2004 C.Zanna; A.M.Porcelli; A.Ghelli; V.Carelli; A.Martinuzzi; M.Rugolo
Cellular and mitochondrial determination of low molecular mass organic acids by LC-MS/MS
2018 Fiori, Jessica; Amadesi, Elisa; Fanelli, Flaminia; Tropeano, Concetta Valentina; Rugolo, Michela; Gotti, Roberto
Clonal expansion of mtDNA deletions: different disease models assessed by digital droplet PCR in single muscle cells.
2018 Trifunov S., Pyle A., Valentino ML., Liguori R., Yu-Wai-Man P., Burté F., Duff J., Kleinle S., Diebold I., Rugolo M., Horvath R., Carelli V.
Coenzyme Q biosynthesis inhibition induces HIF-1α stabilization and metabolic switch toward glycolysis
2021 Liparulo, Irene; Bergamini, Christian; Bortolus, Marco; Calonghi, Natalia; Gasparre, Giuseppe; Kurelac, Ivana; Masin, Luca; Rizzardi, Nicola; Rugolo, Michela; Wang, Wenping; Aleo, Serena J; Kiwan, Alisar; Torri, Cristian; Zanna, Claudia; Fato, Romana
Complex II phosphorylation is triggered by unbalanced redox homeostasis in cells lacking complex III
2018 Tropeano, Concetta Valentina; Fiori, Jessica; Carelli, Valerio; Caporali, Leonardo; Daldal, Fevzi; Ghelli, Anna Maria; Rugolo, Michela
Cybrids with mtDNA mutations causing Leber’s hereditary optic neuropathy are sensitized to apoptotic death induced by a mitochondrial oxidative stress
2006 A. M. Ghelli; C. Zanna; V. Carelli; A. Martinuzzi; M. Rugolo
Deciphering OPA1 mutations pathogenicity by combined analysis of human, mouse and yeast cell models
2018 Del Dotto, Valentina; Fogazza, Mario; Musiani, Francesco; Maresca, Alessandra; Aleo, Serena J.; Caporali, Leonardo; La Morgia, Chiara; Nolli, Cecilia; Lodi, Tiziana; Goffrini, Paola; Chan, David; Carelli, Valerio; Rugolo, Michela; Baruffini, Enrico; Zanna, Claudia*
| Titolo | Autore(i) | Anno | Periodico | Editore | Tipo | File |
|---|---|---|---|---|---|---|
| 'Behr syndrome' with OPA1 compound heterozygote mutations | Carelli, Valerio; Sabatelli, Mario; Carrozzo, Rosalba; Rizza, Teresa; Schimpf, Simone; Wissinger,... Bernd; Zanna, Claudia; Rugolo, Michela; La Morgia, Chiara; Caporali, Leonardo; Carbonelli, Michele; Barboni, Piero; Tonon, Caterina; Lodi, Raffaele; Bertini, Enrico | 2015-01-01 | BRAIN | - | 1.01 Articolo in rivista | - |
| A cellular model for cancer progression: Role of mitochondrial mutations and metabolism | G. Romeo; G. Gasparre; A.M. Porcelli; M. Rugolo | 2010-01-01 | JOURNAL OF BIOTECHNOLOGY | - | 4.02 Riassunto (Abstract) | - |
| A clinically complex form of dominant optic atrophy (OPA8) maps on chromosome 16. | Carelli V.; Schimpf S.; Fuhrmann N.; Valentino M.L.; Zanna C.; Iommarini L.; Papke M.; Schaich S....; Tippmann S.; Baumann B.; Barboni P.; Longanesi L.; Rugolo M.; Ghelli A.; Alavi M.V.; Youle R.J.; Bucchi L.; Carroccia R.; Giannoccaro M.P.; Tonon C.; Lodi R.; Cenacchi G.; Montagna P.; Liguori R.; Wissinger B. | 2011-01-01 | HUMAN MOLECULAR GENETICS | - | 1.01 Articolo in rivista | - |
| A Mutation Threshold Distinguishes the Antitumorigenic Effects of the Mitochondrial Gene MTND1, an Oncojanus Function | Gasparre G; Kurelac I; Capristo M; Iommarini L; Ghelli A; Ceccarelli C; Nicoletti G; Nanni P; De ...Giovanni C; Scotlandi K; Betts CM; Carelli V; Lollini PL; Romeo G; Rugolo M; Porcelli AM | 2011-01-01 | CANCER RESEARCH | - | 1.01 Articolo in rivista | - |
| A novel in-frame 18-bp microdeletion in MT-CYB causes a multisystem disorder with prominent exercise intolerance. | Carossa V;Ghelli A;Tropeano CV;Valentino ML;Iommarini L;Maresca A;Caporali L;Morgia CL;Liguori R;...Barboni P;Carbonelli M;Rizzo G;Tonon C;Lodi R;Martinuzzi A;Nardo VD;Rugolo M;Ferretti L;Gandini F;Pala M;Achilli A;Olivieri A;Torroni A;Carelli V | 2014-01-01 | HUMAN MUTATION | - | 1.01 Articolo in rivista | - |
| AIF and endonuclease G are involved in the caspase-indepenent death of cybrids with LHON mutations | A.M.Porcelli; C. Zanna; A. Montanaro; V.Carelli; A.Ghelli; M.Rugolo | 2004-01-01 | - | s.n | 4.02 Riassunto (Abstract) | - |
| Alterations in the supramolecular interactions of respiratory chain complexes and enhanced superoxide production by the cytochrome b Y278C mutation which causes a multisystem disorder | Ghelli A.; Tropeano C.V.; Calvaruso M.A.; Marchesini A.; Iommarini L.; Porcelli A.M.; Zanna C.; G...asparre G.; Kurelac I.; De Nardo V.; Martinuzzi A.; Vissing J.; Selamoglu N.; Daldal F.; Rugolo M. | 2012-01-01 | BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS | - | 4.02 Riassunto (Abstract) | - |
| An inherited mitochondrial DNA disruptive mutation shifts to homoplasmy in oncocytic tumor cells. | G.Gasparre; L. Iommarini; A.M. Porcelli; M. Lang; G.G. Ferri; I.Kurelac; E. Mariani; L.F. Pennisi...; E. Pasquini; G. Pasquinelli; A. Ghelli; E. Bonora; C. Ceccarelli; M. Rugolo; N. Salfi; G. Romeo; V. Carelli. | 2009-01-01 | HUMAN MUTATION | - | 1.01 Articolo in rivista | - |
| Apoptosis induced by staurosporine in ECV304 cells requires cell shrinkage and upregulation of Cl- conductance | A.M. PORCELLI; A. GHELLI; C. ZANNA; P. VALENTE; S. FERRONI; M. RUGOLO | 2004-01-01 | CELL DEATH AND DIFFERENTIATION | - | 1.01 Articolo in rivista | - |
| ATP depletion and caspase independent death of cybrids bearing Leber's Hereditary Optic neuropathy MTDNA mutations incubated in galactose medium. A model for endonuclease G-mediated apoptosis | A. Ghelli; C. Zanna; A.M. Porcelli; V. Carelli; M. Rugolo | 2004-01-01 | - | Dipartimento Biologia Ev. SP. | 4.02 Riassunto (Abstract) | - |
| Biochimica | Ascenzi P.; Contestabile R.; Di Salvo M.L.; Faraone Mennella M.R.; Fusi P.; Lenaz G.; Pascarella ...S.; Quesada P.M.; Rugolo M.; Sorrentino S.; Tortora P.; Turina P. | 2007-01-01 | - | Idelson-Gnocchi | 3.02 Curatela | - |
| Bioenergetics shapes cellular death pathways in Leber’s hereditary optic neuropathy: a model of mitochondrial neurodegeneration | CARELLI V; RUGOLO M; SGARBI G; GHELLI A; ZANNA C; BARACCA A; LENAZ G; NAPOLI E; MARTINUZZI A; SOL...AINI G. | 2004-01-01 | BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS | - | 1.01 Articolo in rivista | - |
| Caspase-independent death of Leber's hereditary optic neuropathy cybrids is driven by energetic failure and mediated by AIF and Endonuclease G. | ZANNA C.; GHELLI A.; PORCELLI AM.; MARTINUZZI A.; Carelli V.; RUGOLO M. | 2005-01-01 | APOPTOSIS | - | 1.01 Articolo in rivista | - |
| Cell death of fibroblasts derived from patients with Leber’s hereditary optic neuropathy mtDNA mutations | C.Zanna; A.M.Porcelli; A.Ghelli; V.Carelli; A.Martinuzzi; M.Rugolo | 2004-01-01 | - | s.n | 4.02 Riassunto (Abstract) | - |
| Cellular and mitochondrial determination of low molecular mass organic acids by LC-MS/MS | Fiori, Jessica; Amadesi, Elisa; Fanelli, Flaminia; Tropeano, Concetta Valentina; Rugolo, Michela;... Gotti, Roberto | 2018-01-01 | JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS | - | 1.01 Articolo in rivista | - |
| Clonal expansion of mtDNA deletions: different disease models assessed by digital droplet PCR in single muscle cells. |
Trifunov S., Pyle A., Valentino ML., Liguori R., Yu-Wai-Man P., Burté F., Duff J., Kleinle S., Di...ebold I., Rugolo M., Horvath R., Carelli V. |
2018-01-01 | SCIENTIFIC REPORTS | - | 1.01 Articolo in rivista | Trifunov SciRep 2018ms.pdf |
| Coenzyme Q biosynthesis inhibition induces HIF-1α stabilization and metabolic switch toward glycolysis | Liparulo, Irene; Bergamini, Christian; Bortolus, Marco; Calonghi, Natalia; Gasparre, Giuseppe; Ku...relac, Ivana; Masin, Luca; Rizzardi, Nicola; Rugolo, Michela; Wang, Wenping; Aleo, Serena J; Kiwan, Alisar; Torri, Cristian; Zanna, Claudia; Fato, Romana | 2021-01-01 | THE FEBS JOURNAL | - | 1.01 Articolo in rivista | - |
| Complex II phosphorylation is triggered by unbalanced redox homeostasis in cells lacking complex III | Tropeano, Concetta Valentina; Fiori, Jessica; Carelli, Valerio; Caporali, Leonardo; Daldal, Fevzi...; Ghelli, Anna Maria; Rugolo, Michela | 2018-01-01 | BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS | - | 1.01 Articolo in rivista | - |
| Cybrids with mtDNA mutations causing Leber’s hereditary optic neuropathy are sensitized to apoptotic death induced by a mitochondrial oxidative stress | A. M. Ghelli; C. Zanna; V. Carelli; A. Martinuzzi; M. Rugolo | 2006-01-01 | - | s.n | 4.02 Riassunto (Abstract) | - |
| Deciphering OPA1 mutations pathogenicity by combined analysis of human, mouse and yeast cell models | Del Dotto, Valentina; Fogazza, Mario; Musiani, Francesco; Maresca, Alessandra; Aleo, Serena J.; C...aporali, Leonardo; La Morgia, Chiara; Nolli, Cecilia; Lodi, Tiziana; Goffrini, Paola; Chan, David; Carelli, Valerio; Rugolo, Michela; Baruffini, Enrico; Zanna, Claudia* | 2018-01-01 | BIOCHIMICA ET BIOPHYSICA ACTA. MOLECULAR BASIS OF DISEASE | - | 1.01 Articolo in rivista | 56_2018_DelDotto_BBAMolBasisDisease.pdf |