CRIS Current Research Information System

BISI, ALESSANDRA
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
NA - Nord America 5.639
AS - Asia 4.556
EU - Europa 3.739
AF - Africa 289
SA - Sud America 232
OC - Oceania 10
Continente sconosciuto - Info sul continente non disponibili 4
Totale 14.469
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 5.565
CN - Cina 1.371
SG - Singapore 1.354
IT - Italia 870
VN - Vietnam 850
GB - Regno Unito 802
DE - Germania 529
HK - Hong Kong 335
SE - Svezia 327
UA - Ucraina 229
IN - India 227
RU - Federazione Russa 208
BR - Brasile 166
FR - Francia 151
NL - Olanda 134
IE - Irlanda 122
CI - Costa d'Avorio 100
JO - Giordania 99
KR - Corea 99
ZA - Sudafrica 77
JP - Giappone 66
BG - Bulgaria 60
FI - Finlandia 59
TG - Togo 58
EE - Estonia 52
CA - Canada 48
ID - Indonesia 34
AR - Argentina 31
CH - Svizzera 30
IR - Iran 30
PL - Polonia 29
SC - Seychelles 28
AT - Austria 25
ES - Italia 19
GR - Grecia 18
MX - Messico 17
CZ - Repubblica Ceca 16
BE - Belgio 15
PK - Pakistan 15
HR - Croazia 13
EC - Ecuador 12
TR - Turchia 11
BD - Bangladesh 10
LB - Libano 8
MY - Malesia 8
NG - Nigeria 8
AU - Australia 7
EG - Egitto 7
LT - Lituania 7
CO - Colombia 6
IQ - Iraq 6
PT - Portogallo 6
CL - Cile 5
KZ - Kazakistan 5
HU - Ungheria 4
PE - Perù 4
TH - Thailandia 4
A2 - ???statistics.table.value.countryCode.A2??? 3
AE - Emirati Arabi Uniti 3
BY - Bielorussia 3
DZ - Algeria 3
GT - Guatemala 3
KE - Kenya 3
NZ - Nuova Zelanda 3
PH - Filippine 3
PS - Palestinian Territory 3
PY - Paraguay 3
SA - Arabia Saudita 3
UZ - Uzbekistan 3
AL - Albania 2
KW - Kuwait 2
LK - Sri Lanka 2
MD - Moldavia 2
NO - Norvegia 2
PA - Panama 2
RO - Romania 2
TN - Tunisia 2
UY - Uruguay 2
VE - Venezuela 2
AO - Angola 1
AZ - Azerbaigian 1
BA - Bosnia-Erzegovina 1
BB - Barbados 1
BO - Bolivia 1
CR - Costa Rica 1
CW - ???statistics.table.value.countryCode.CW??? 1
DO - Repubblica Dominicana 1
GH - Ghana 1
GI - Gibilterra 1
HN - Honduras 1
KG - Kirghizistan 1
LA - Repubblica Popolare Democratica del Laos 1
MM - Myanmar 1
OM - Oman 1
RS - Serbia 1
SD - Sudan 1
Totale 14.469
Salva come PNG Salva come JPEG
Città #
Singapore 850
Southend 702
Ashburn 583
Fairfield 528
Chandler 521
Santa Clara 363
Hong Kong 333
Woodbridge 298
Bologna 291
Dong Ket 251
Hefei 248
Houston 247
Wilmington 245
Seattle 240
Cambridge 207
Beijing 188
Princeton 175
Ho Chi Minh City 164
Ann Arbor 163
Jacksonville 151
Hanoi 139
Boardman 134
Dublin 122
New York 100
Abidjan 99
Amman 99
Seoul 97
Dallas 76
Westminster 74
Los Angeles 72
Nanjing 71
Padova 65
Tokyo 63
Sofia 60
Lomé 58
Munich 55
Berlin 54
Buffalo 54
Bremen 47
Jinan 44
San Diego 41
Shenyang 39
Helsinki 37
Milan 37
Redondo Beach 37
Saint Petersburg 37
Redmond 32
Jakarta 28
Hebei 27
Mülheim 27
Nanchang 27
Bern 26
Guangzhou 26
Tianjin 25
Bengaluru 24
Frankfurt am Main 22
Shanghai 22
Changsha 21
Quận Bình Thạnh 21
São Paulo 21
Council Bluffs 20
Nuremberg 20
Jiaxing 19
Haiphong 18
Medford 18
Warsaw 18
Mahé 17
Olalla 16
Redwood City 16
Venezia 16
Brussels 15
Da Nang 15
Des Moines 15
Mountain View 15
Phoenix 15
Vienna 15
Zhengzhou 15
Boydton 14
Chicago 14
Dearborn 14
Falkenstein 13
Kunming 13
Brooklyn 12
Hangzhou 12
London 12
Toronto 12
Turin 12
Turku 12
Montreal 11
Taiyuan 11
Verona 11
Düsseldorf 10
Fremont 10
Lappeenranta 10
Modena 10
San Giorgio di Piano 10
Wuhan 10
Atlanta 9
Falls Church 9
Hải Dương 9
Totale 9.451
Salva come PNG Salva come JPEG
Nome #
1,4-dihydropyridine derivatives as calcium channel modulators: the role of 3-methoxy-flavone moiety 324
Discovery of novel benzofuran-based compounds with neuroprotective and immunomodulatory properties for Alzheimer's disease treatment 288
Benzofuran-Based Hybrid Compounds for the Inhibition of Cholinesterase Activity, Abeta Amyloid Aggregation, and Abeta Neurotoxicity 265
Cholinesterase inhibitors: xanthostigmine derivatives blocking the acetylcholinesterase-induced beta-amyloid aggregation. 236
Multitarget Strategy to Address Alzheimer's Disease: Design, Synthesis, Biological Evaluation, and Computational Studies of Coumarin-Based Derivatives 233
Structure-Activity Relationships and Binding Mode in the Human Acetylcholinesterase Active Site of Pseudo-Irreversible Inhibitors Related to Xanthostigmine 225
Progettazione e sintesi di derivati benzofuranici per la malattia di Alzheimer 217
Analogues of the dual acetylcholinesterase inhibitor AP2238: synthesis and SAR 195
Design, synthesis and biological profile of new inhibitors of multidrug resistance associated proteins carrying a polycyclic scaffold 191
2-Arylbenzofuran-based molecules as multipotent Alzheimer's disease modifying agents 188
Benzophenones as xanthone-open model CYP11B1 inhibitors potentially useful for promoting wound healing 187
Versatility of the Curcumin Scaffold: Discovery of Potent and Balanced Dual BACE-1 and GSK-3β Inhibitors 184
Fatty Acid Amide Hydrolase (FAAH), Acetylcholinesterase (AChE), and Butyrylcholinesterase (BuChE): Networked Targets for the Development of Carbamates as Potential Anti-Alzheimer's Disease Agents 183
Benzophenone-based derivatives: A novel series of potent and selective dual inhibitors of acetylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation 182
Exploiting the chalcone scaffold to develop multifunctional agents for Alzheimer’s disease 182
Extensive SAR and computational studies of 3-{4-[(benzylmethylamino)methyl]phenyl}-6,7-dimethoxy-2H-2-chromenone (AP2238) derivatives. 181
SAR and binding mode at the h-AChE active site of pseudo-irreversible inhibitors related to Xanthostigmine 181
Chalcones induce apoptosis, autophagy and reduce spreading in osteosarcoma 3D models 179
Targeting neuronal calcium channels and GSK3β for Alzheimer's disease with naturally-inspired Diels-Alder adducts 178
Cardiovascular profile of xanthone-based 1,4 dihydropyridines bearing a lidoflazine pharmacophore fragment 175
Identification of chalcone-based antileishmanial agents targeting trypanothione reductase 173
Targeting the multifaceted neurotoxicity of Alzheimer's disease by tailored functionalisation of the curcumin scaffold 169
Identification of a new tamoxifen-xanthene hybrid as pro-apoptotic anticancer agent 167
Enantioselective nonsteroidal aromatase inhibitors identified through a multidisciplinary medicinal chemistry approach 163
CHOLINESTERASE INHIBITORS: SAR AND ENZYME INHIBITORY ACTIVITY OF 3-[omega-(BENZYLMETHYLAMINO)ALKOXY]XANTHEN-9-ONES 163
Interplay Between Endocannabinoid System and Neurodegeneration: Focus on Polypharmacology 162
Anthracene Based Compounds as New L-type Ca2+ Channel Blockers: Design, Synthesis, and Full Biological Profile 162
Natural-like Chalcones with Antitumor Activity on Human MG63 Osteosarcoma Cells 160
Naturally inspired molecules as multifunctional agents for Alzheimer's disease treatment 158
Emerging targets in neurodegeneration: new opportunities for Alzheimer's disease treatment? 157
A Computational Assay of Estrogen Receptor α Antagonists Reveals the Key Common Structural Traits of Drugs Effectively Fighting Refractory Breast Cancers 157
Novel Curcumin-Diethyl Fumarate Hybrid as a Dualistic GSK-3β Inhibitor/Nrf2 Inducer for the Treatment of Parkinson's Disease 156
Curcumin-1,2,3-triazole conjugation for targeting the cancer apoptosis machinery. 154
Lead optimization providing a series of flavone derivatives as potent nonsteroidal inhibitors of the cytochrome P450 aromatase enzyme 152
Balanced dual acting compounds targeting aromatase and estrogen receptor α as an emerging therapeutic opportunity to counteract estrogen responsive breast cancer 152
Polycyclic maleimide-based derivatives as first dual modulators of neuronal calcium channels and GSK-3β for Alzheimer's disease treatment 148
Derivati a struttura benzofenonica come inibitori dell'acetilcolinesterasi 147
Fluorinated benzophenone derivatives: balanced multipotent agents for Alzheimer's disease 147
Nonsteroidal Aromatase inhibitors: synthesis and evaluation of new flavone derivatives 146
Homopterocarpanes as bridged triarylethylene analogues: synthesis and antagonistic effects in human MCF-7 breast cancer cells 146
Design, synthesis, and evaluation of benzophenone derivatives as novel acetylcholinesterase inhibitors 144
Single-digit nanomolar inhibitors lock the aromatase active site via a dualsteric targeting strategy 142
Imidazolylmethylbenzophenones as highly potent aromatase inhibitors. 141
Antitumor profile of new phenothiazine derivatives 140
Multifaceted activity of polyciclic MDR revertant agents in drug-resistant leukemic cells: Role of the spacer 140
PREPARATION AND STEREOCHEMICAL CHARACTERIZATION OF ENANTIOMERIC HOMOISOFLAVONES ACTIVE AS AROMATASE INHIBITORS 139
New derivatives of xanthenone-4-acetic acid: synthesis, pharmacological profile and effect on TNF-alpha and NO production by human immune cells 139
In vitro studies of flavon-8-acetic acid analogues 138
New Coumarin derivatives as cholinergic and cannabinoid system modulators 138
Benzophenone derivatives as Inhibitors of Acetylcholinesterase 136
In vitro biological activity of new analogues of flavon-8-acetic acid 135
Improved eradication efficacy of a combination of newly identified antimicrobial agents in C. albicans and S. aureus mixed-species biofilm 133
Studies on cytostatic and cytotoxic activity of new flavopiridol analogues 132
New potent P-glycoprotein inhibitors carrying a polycyclic scaffold 132
Hybrid drugs for Alzheimer's disease: new indanone derivatives bearing a pharmacophoric fragment of AP2238 131
Multi-target strategy to address Alzheimer’s disease: Design, synthesis and biological evaluation of new tacrine-based dimers 130
Novel Aldosterone Synthase Inhibitors with Extended Carbocyclic Skeleton by a Combined Ligand-Based and Structure-Based Drug Design Approach 128
Design, Synthesis, and Biological and Crystallographic Evaluation of Novel Inhibitors ofPlasmodium falciparumEnoyl-ACP-reductase (PfFabI) 126
Functionalization of the chalcone scaffold for the discovery of novel lead compounds targeting fungal infections 125
Reconsidering Aromatase for Breast Cancer Treatment: New Roles for an Old Target 125
Naturally Inspired Coumarin Derivatives in Alzheimer’s Disease Drug Discovery: Latest Advances and Current Challenges 124
null 123
Switching from Aromatase Inhibitors to Dual Targeting Flavonoid-Based Compounds for Breast Cancer Treatment 121
Design of Multifunctional Compounds for Cardiovascular Disease: From Natural Scaffolds to “Classical” Multitarget Approach 121
Targeting the Bacterial Membrane with a New Polycyclic Privileged Structure: A Powerful Tool To Face Staphylococcus aureus Infections 120
Hybrid-Based Multi-Target Ligands for the Treatment of Alzheimer's Disease 119
Novel highly potent and selective nonsteroidal aromatase inhibitors: synthesis, biological evaluation and structure-activity relationships investigation 119
Polycyclic Maleimide-based Scaffold as New Privileged Structure for Navigating the Cannabinoid System Opportunities 119
Flavonoid-inspired vascular disrupting agents: Exploring flavone-8-acetic acid and derivatives in the new century 119
null 118
From AChE to BACE1 inhibitors: The role of the amine on the indanone scaffold 117
Targeting Orthosteric and Allosteric Pockets of Aromatase via Dual-Mode Novel Azole Inhibitors 117
Multidrug resistance reverting activity and antitumor profile of new phenothiazine derivatives 116
The first dual ChE/FAAH inhibitors: new perspectives for Alzheimer's disease? 114
The ability of coumarin-, flavanon- and flavonol-analogues of flavone acetic acid to stimulate human monocytes. 112
Modulation of Cytochromes P450 with Xanthone-Based Molecules: From Aromatase to Aldosterone Synthase and Steroid 11β-Hydroxylase Inhibition 111
Mono- or di-fluorinated analogues of Flavone-8-acetic acid: synthesis and in vitro biological activity 109
Imidazolylmethylxanthones as potent inhibitors of cytochrome P450 aromatase 109
New potent inhibitors of cytochrome P450 aromatase 108
Nonsteroidal aromatase inhibitors for the treatment of breast cancer: an update. 108
Farmaci cardiaci 106
null 105
From nonsteroidal aromatase inhibitors to multifunctional drug candidates: classic and innovative strategies for the treatment of breast cancer. 101
Small-molecule inhibitors/modulators of amyloid-β peptide aggregation and toxicity for the treatment of Alzheimer's disease: a patent review (2010 – 2012) 99
Chalcone-based carbamates for Alzheimer's disease treatment 96
Coumarin derivatives as potential antitumor agents: Growth inhibition, apoptosis induction and multidrug resistance reverting activity 94
Tackling Alzheimer's Disease with Existing Drugs:A Promising Strategy for Bypassing Obstacles 90
Hitting drug-resistant malaria infection with triazole-linked flavonoid–chloroquine hybrid compounds 88
Chromone-based small molecules for multistep shutdown of arachidonate pathway: Simultaneous inhibition of COX-2, 15-LOX and mPGES-1 enzymes 86
null 82
null 79
null 76
null 70
Recent progress on curcumin-based therapeutics: a patent review (2012-2016). Part I: Curcumin 68
null 67
New approaches to the treatment of Alzheimer's disease. 64
3-(4-{[benzyl(methyl)amino]methyl}-phenyl)-6,7-dimethoxy-2H-2-chromenone (AP2238) inhibits both acetylcholinesterase and acetylcholinesterase-induced β-amyloid aggregation: A dual function lead for Alzheimer's disease therapy 62
Acetylcholinesterase inhibitors: SAR and kinetic studies on ω-[N-methyl-N-(3-alkylcarbamoyloxyphenyl]methyl] aminoalkoxyaryl derivatives 59
Recent progress on curcumin-based therapeutics: a patent review (2012-2016). Part II: curcumin derivatives in cancer and neurodegeneration 59
null 58
Totale 13.940
Salva come PNG Salva come JPEG
Categoria #
all - tutte 42.868
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 42.868
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021915 0 0 0 0 0 76 28 132 100 72 93 414
2021/20221.620 146 42 102 86 133 84 47 158 91 126 308 297
2022/20232.205 199 241 92 269 160 168 66 130 469 68 166 177
2023/2024704 37 81 40 93 53 204 41 32 14 35 35 39
2024/20252.615 85 356 282 140 544 139 218 70 61 186 148 386
2025/20263.235 720 553 601 455 652 254 0 0 0 0 0 0
Totale 14.821