CRIS Current Research Information System

GHELLI, ANNA MARIA
 Distribuzione geografica
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Continente #
NA - Nord America 5.205
AS - Asia 4.816
EU - Europa 4.314
AF - Africa 399
SA - Sud America 214
OC - Oceania 11
Continente sconosciuto - Info sul continente non disponibili 4
Totale 14.963
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Nazione #
US - Stati Uniti d'America 5.131
CN - Cina 1.353
IT - Italia 1.324
SG - Singapore 1.295
VN - Vietnam 1.049
GB - Regno Unito 757
DE - Germania 456
SE - Svezia 386
HK - Hong Kong 319
FR - Francia 235
UA - Ucraina 234
IN - India 200
RU - Federazione Russa 186
BR - Brasile 161
CI - Costa d'Avorio 155
KR - Corea 139
IE - Irlanda 128
NL - Olanda 117
FI - Finlandia 101
JP - Giappone 100
BD - Bangladesh 94
ZA - Sudafrica 79
TG - Togo 74
CH - Svizzera 69
SC - Seychelles 64
EE - Estonia 51
JO - Giordania 46
ES - Italia 43
CA - Canada 38
AT - Austria 33
BG - Bulgaria 32
ID - Indonesia 32
PL - Polonia 30
BE - Belgio 29
TR - Turchia 29
PK - Pakistan 28
CZ - Repubblica Ceca 27
MX - Messico 27
AR - Argentina 25
PH - Filippine 24
TH - Thailandia 20
IQ - Iraq 17
TW - Taiwan 15
GR - Grecia 12
AE - Emirati Arabi Uniti 10
IR - Iran 10
SA - Arabia Saudita 10
AU - Australia 9
CL - Cile 9
DK - Danimarca 9
HR - Croazia 9
SK - Slovacchia (Repubblica Slovacca) 9
PT - Portogallo 8
LT - Lituania 7
RO - Romania 7
SN - Senegal 7
CO - Colombia 5
DZ - Algeria 5
EC - Ecuador 5
LB - Libano 5
MA - Marocco 5
NG - Nigeria 5
NO - Norvegia 4
SI - Slovenia 4
UZ - Uzbekistan 4
JM - Giamaica 3
MT - Malta 3
MY - Malesia 3
PE - Perù 3
PY - Paraguay 3
XK - ???statistics.table.value.countryCode.XK??? 3
DO - Repubblica Dominicana 2
ET - Etiopia 2
KZ - Kazakistan 2
NP - Nepal 2
VE - Venezuela 2
BH - Bahrain 1
BO - Bolivia 1
BY - Bielorussia 1
BZ - Belize 1
CY - Cipro 1
EG - Egitto 1
EU - Europa 1
GT - Guatemala 1
HU - Ungheria 1
IL - Israele 1
KE - Kenya 1
KW - Kuwait 1
LK - Sri Lanka 1
LV - Lettonia 1
MD - Moldavia 1
MM - Myanmar 1
MN - Mongolia 1
NI - Nicaragua 1
NZ - Nuova Zelanda 1
PG - Papua Nuova Guinea 1
PS - Palestinian Territory 1
QA - Qatar 1
TJ - Tagikistan 1
TN - Tunisia 1
Totale 14.962
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Città #
Singapore 878
Southend 623
Ashburn 550
Bologna 444
Chandler 376
Fairfield 376
Hefei 351
Hong Kong 294
San Jose 274
Santa Clara 250
Ann Arbor 233
Ho Chi Minh City 233
Woodbridge 192
Hanoi 188
Houston 176
Seattle 169
Jacksonville 160
Wilmington 160
Abidjan 155
Princeton 149
Dallas 140
Beijing 126
Dublin 125
Seoul 125
Cambridge 123
Dong Ket 120
Boardman 110
New York 106
Council Bluffs 102
Los Angeles 87
Tokyo 85
Helsinki 76
Lauterbourg 75
Milan 75
Lomé 74
Padova 73
Westminster 64
Bern 53
Nanjing 51
Berlin 49
Amman 46
Buffalo 41
Redmond 41
Turin 38
Saint Petersburg 37
Bengaluru 36
Jinan 36
Mülheim 31
Changsha 30
Modena 30
Rome 30
San Diego 30
Sofia 30
São Paulo 30
Da Nang 28
Medford 28
Brussels 27
Haiphong 27
Jakarta 26
Florence 25
Guangzhou 25
Shanghai 25
Frankfurt am Main 24
Hebei 24
Johannesburg 24
Munich 24
Vienna 24
Redondo Beach 23
Amsterdam 22
Nanchang 22
Parma 22
Redwood City 22
Shenyang 22
Tianjin 21
Shenzhen 20
Phoenix 18
Taizhou 18
Mahé 17
Warsaw 17
Naples 16
Orem 16
Prague 16
Dhaka 15
London 15
Stockholm 15
Verona 15
Chennai 14
Falkenstein 14
Montreal 14
Norwalk 14
Valladolid 14
Biên Hòa 13
Des Moines 13
Jiaxing 13
Miami 13
San Francisco 13
Turku 13
Zhengzhou 13
Kuban 12
Paris 12
Totale 9.424
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Nome #
Genetic variants affecting NQO1 protein levels impact the efficacy of idebenone treatment in Leber hereditary optic neuropathy 320
Inducing respiratory complex I impairment elicits an increase in PGC1α in ovarian cancer 320
Respiratory complex I deficiency triggers OMA1-mediated integrated stress response and affects lipid homeostasis during glucose restriction 306
New Insights on Rotenone Resistance of Complex I Induced by the m.11778G>A/MT-ND4 Mutation Associated with Leber’s Hereditary Optic Neuropathy 278
Different mtDNA mutations modify tumor progression in dependence of the degree of respiratory complex I impairment 272
MicroRNA and Metabolic Profiling of a Primary Ovarian Neuroendocrine Carcinoma Pulmonary-Type Reveals a High Degree of Similarity with Small Cell Lung Cancer 261
Respiratory complex I is essential to induce a Warburg profile in mitochondria-defective tumor cells 260
Adult Leigh Syndrome Associated with the m.15635T>C Mitochondrial DNA Variant Affecting the Cytochrome b (MT-CYB) Gene 253
Defective oxidative phosphorylation in thyroid oncocytic carcinoma is associated with pathogenic mitochondrial DNA mutations affecting complexes I and III 252
A clinically complex form of dominant optic atrophy (OPA8) maps on chromosome 16. 243
NDUFS3 knockout cancer cells and molecular docking reveal specificity and mode of action of anti-cancer respiratory complex I inhibitors 240
An inherited mitochondrial DNA disruptive mutation shifts to homoplasmy in oncocytic tumor cells. 239
The background of mitochondrial DNA haplogroup J increases the sensitivity of Leber's hereditary optic neuropathy cells to 2,5-hexanedione toxicity. 234
Apoptosis induced by staurosporine in ECV304 cells requires cell shrinkage and upregulation of Cl- conductance 229
Cigarette toxicity triggers Leber's hereditary optic neuropathy by affecting mtDNA copy number, oxidative phosphorylation and ROS detoxification pathways 226
Respiratory complex I null cancer cells and molecular docking reveal specificity and mode of action inhibitors with anticancer activity 225
Haplogroup J mitogenomes are the most sensitive to the pesticide rotenone: Relevance for human diseases 225
The antioxidant function of Bcl-2 preserves cytoskeletal stability of cells with defective respiratory complex I. 223
Alterations in the supramolecular interactions of respiratory chain complexes and enhanced superoxide production by the cytochrome b Y278C mutation which causes a multisystem disorder 221
Unravelling the Effects of the Mutation m.3571insC/MT-ND1 on Respiratory Complexes Structural Organization 218
The ND1 gene of complex I is a mutational hot spot for Leber's hereditary optic neuropathy. 216
Mitochondrial chaperonin DNAJC15 promotes vulnerability to ferroptosis of chemoresistant ovarian cancer cells 215
Drug repositioning as a therapeutic strategy for neurodegenerations associated with OPA1 mutations 214
A computational study to assess the pathogenicity of single or combinations of missense variants on respiratory complex I 208
Metabolomics hallmarks OPA1 variants correlating with their in-vitro phenotype and predicting clinical severity 208
pH difference across the outer mitochondrial membrane measured with a green fluorescent protein mutant 207
Reactive Oxygen Species Produced by Mutated Mitochondrial Respiratory Chains of Entire Cells Monitored Using Modified Microelectrodes 207
Mild phenotypes and proper supercomplex assembly in human cells carrying the homoplasmic m.15557G > A mutation in cytochrome b gene 203
Cybrid studies establish the causal link between the mtDNA m.3890G>A/MT-ND1 mutation and optic atrophy with bilateral brainstem lesions. 202
Disruptive mitochondrial DNA mutations in complex I subunits are markers of oncocytic phenotype in thyroid tumours. 199
Effect of energetic stress and the ceramide analogue C6-ceramide on thyroid oncocytoma cell lines. 198
The cytochrome B p.278Y>C mutation causative of a multisystem disorder enhances superoxide production and alters supramolecular interactions of respiratory chain complexes 195
Caspase-independent death of Leber's hereditary optic neuropathy cybrids is driven by energetic failure and mediated by AIF and Endonuclease G. 195
A Mutation Threshold Distinguishes the Antitumorigenic Effects of the Mitochondrial Gene MTND1, an Oncojanus Function 193
Fine-tuning of the respiratory complexes stability and supercomplexes assembly in cells defective of complex III 192
Impaired plasma membrane calcium ATPase activity and mitochondrial dysfunction contribute to calcium dysregulation in Fabry disease-related painful neuropathy 190
Mitochondrial Chaperonin MCJ Promotes Vulnerability to Ferroptosis of Chemoresistant Ovarian Cancer Cells – Dataset 187
ATP depletion and caspase independent death of cybrids bearing Leber's Hereditary Optic neuropathy MTDNA mutations incubated in galactose medium. A model for endonuclease G-mediated apoptosis 186
Effect of energetic stress and the ceramide analogue C6-ceramide on thyroid oncocytoma cell lines 184
A novel in-frame 18-bp microdeletion in MT-CYB causes a multisystem disorder with prominent exercise intolerance. 181
Cell death of fibroblasts derived from patients with Leber’s hereditary optic neuropathy mtDNA mutations 180
Effect of energetic stress and the ceramide analogue C6-ceramide on thyroid oncocytoma cell lines 176
Green Tea Modulates Alpha-1-Adrenergic Stimulated Glucose Transport in Cultured Rat Cardiomyocytes 176
Green tea modulates a-1-adrenergic stimulated glucose transport in cultured cardiomyocytes via protein kinase C beta and delta isoforms 175
Evaluation of the energetic efficiency of cells derived from patients with dominant optic neuropathy (DOA). 164
Use of bacterial photosynthetic vesicles to evaluate the effect of ionic liquids on the permeability of biological membranes 163
Dominant Optic Atrophy (DOA) and Sensorineural Hearing Loss: Clinical, Biochemical, Spectroscopic and Molecular Genetic Study of a Large Italian Pedigree Linked to a New Locus on Chromosome 16 163
The genetic and metabolic signature of oncocytic transformation implicates HIF1alpha destabilization 163
Mitochondrial metabolism and energy sensing in tumor progression 163
Determination of mitochondrial fusion in fibroblasts from dominant optic atrophy patients bearing the c.2708delttag OPA1 mutation 159
Protection against oxidant-induced apoptosis by exogenous glutathione in Leber Hereditary Optic Neuropathy cybrids. 158
Respiratory complex I dysfunction due to mitochondrial DNA mutations shifts the voltage threshold for opening of the permeability transition pore toward resting levels 158
Bioenergetics shapes cellular death pathways in Leber’s hereditary optic neuropathy: a model of mitochondrial neurodegeneration 158
Manipulation of Mitochondria Dynamics Reveals Separate Roles for Form and Function in Mitochondria Distribution 158
Biochemical and computational approaches to dissect the effect of MT-CYB pathogenic mutations on respiratory chain activity and assembly 157
MCJ/DNAJC15 mitochondrial chaperone as a metabolic “balance needle” in ovarian cancer chemoresistance 154
Mitochondrial DNA mutations in relation to cancer: the model of thyroid oncocytoma 150
Dominant optic neuropathy: analysis of the energetic efficiency and mitochondrial dynamics 149
AIF and endonuclease G are involved in the caspase-indepenent death of cybrids with LHON mutations 149
Oestrogens ameliorate mitochondrial dysfunction in Leber's hereditary optic neuropathy. 144
Novel mutations in mitochondrial respiratory complexes and their functional relevance in thyroid oncocytoma. 142
The energetic failure caused by severe mutations in the mitochondrial genome is not rescued by Bcl-2 overexpression 141
The effects of idebenone on mitochondrial bioenergetics 141
OPA 1 mutations associated with dominant optic atrophy impair oxidative phosphorylation and mitochondrial fusion. 141
Severe defect of complex I-dependent ATP synthesis shapes the mitochondria-driven path of apoptotic cell death in Leber’s Hereditary Optic Neuropathy. 136
Modelling ND subunits of complex I: Leber’s Hereditary Optic Neuropathy (LHON) pathogenic mutations and non-synonymous population variants in genotype-phenotype correlation 135
Mitochondrial complex I and cell death: a semi-automatic shogun model 132
Complex II phosphorylation is triggered by unbalanced redox homeostasis in cells lacking complex III 132
OPA1 directly interacts with respiratory complexes and AIF. 127
Cybrids with mtDNA mutations causing Leber’s hereditary optic neuropathy are sensitized to apoptotic death induced by a mitochondrial oxidative stress 127
Oxidative phosphorylation dysfunction in fibroblasts bearing different pathological OPA1 mutations. 125
Effect of bcl-2 on the oxidative phosphorylation efficiency of cells with defective respiratory complex I. 125
Impairment of mitochondrial fusion in dominant optic atrophy, a model for selective neurodegeneration 123
Melanopsin-expressing retinal ganglion cells are resistant to cell injury, but not always 122
Organization of the respiratory supercomplexes in cells with defective complex III: Structural features and metabolic consequences 122
Mitochondrial Respiratory Supercomplexes in Physiology and Diseases 121
Exogenous peptides are able to penetrate human cell and mitochondrial membranes, stabilize mitochondrial tRNA structures, and rescue severe mitochondrial defects 116
Energetic efficiency and mitochondrial dynamics in fibroblasts derived from patients with optic neuropathies. 111
Molecular mechanisms of superoxide production by complex III: A bacterial versus human mitochondrial comparative case study. 109
null 109
Respiratory Chain Function and Mitochondrial Dynamics in Leber's Hereditary Optic Neuropathy (LHON) and OPA1-Related Dominant Optic Atrophy (DOA) Fibroblasts. 96
Duplexing complexome profiling with SILAC to study human respiratory chain assembly defects 92
Formation of I2+III2 supercomplex rescues respiratory chain defects 91
null 83
Methods and models for functional studies on mtDNA mutations 72
Targeting estrogen receptor β as preventive therapeutic strategy for Leber's hereditary optic neuropathy 55
Totale 15.268
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Categoria #
all - tutte 39.382
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 39.382
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021312 0 0 0 0 0 0 0 0 0 0 0 312
2021/20221.483 101 48 89 79 108 68 52 106 64 168 354 246
2022/20231.785 176 254 92 234 101 130 61 101 317 48 153 118
2023/2024646 35 69 37 46 49 118 31 47 30 105 41 38
2024/20252.223 102 218 170 136 374 152 141 86 69 149 171 455
2025/20265.384 411 704 598 465 615 294 580 138 803 363 173 240
Totale 15.268