CRIS Current Research Information System

ROBERTI, MARINELLA
 Distribuzione geografica
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Continente #
NA - Nord America 5.124
AS - Asia 4.131
EU - Europa 4.095
AF - Africa 354
SA - Sud America 320
OC - Oceania 11
Continente sconosciuto - Info sul continente non disponibili 1
Totale 14.036
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Nazione #
US - Stati Uniti d'America 5.055
CN - Cina 1.384
SG - Singapore 1.290
IT - Italia 1.149
GB - Regno Unito 729
DE - Germania 547
VN - Vietnam 451
SE - Svezia 350
HK - Hong Kong 313
BR - Brasile 258
IN - India 258
FR - Francia 200
RU - Federazione Russa 188
UA - Ucraina 174
KR - Corea 171
NL - Olanda 162
IE - Irlanda 158
CI - Costa d'Avorio 132
TG - Togo 84
JP - Giappone 76
CH - Svizzera 64
ZA - Sudafrica 60
FI - Finlandia 58
EE - Estonia 57
BG - Bulgaria 55
CA - Canada 47
JO - Giordania 42
NG - Nigeria 42
ES - Italia 33
PL - Polonia 28
AT - Austria 25
TW - Taiwan 25
AR - Argentina 24
BE - Belgio 24
IR - Iran 24
ID - Indonesia 23
TR - Turchia 22
HR - Croazia 20
MX - Messico 20
SC - Seychelles 15
GR - Grecia 12
LT - Lituania 12
AU - Australia 10
BD - Bangladesh 10
EC - Ecuador 10
MT - Malta 10
PK - Pakistan 9
PT - Portogallo 9
CO - Colombia 7
CZ - Repubblica Ceca 7
EG - Egitto 7
PH - Filippine 7
CL - Cile 6
DK - Danimarca 6
MA - Marocco 6
PE - Perù 5
PY - Paraguay 5
RO - Romania 5
DZ - Algeria 4
AE - Emirati Arabi Uniti 3
LB - Libano 3
MY - Malesia 3
SM - San Marino 3
UY - Uruguay 3
UZ - Uzbekistan 3
BY - Bielorussia 2
IL - Israele 2
IQ - Iraq 2
SA - Arabia Saudita 2
VE - Venezuela 2
AD - Andorra 1
AM - Armenia 1
BH - Bahrain 1
CU - Cuba 1
CW - ???statistics.table.value.countryCode.CW??? 1
CY - Cipro 1
GE - Georgia 1
HU - Ungheria 1
KE - Kenya 1
KH - Cambogia 1
LI - Liechtenstein 1
LV - Lettonia 1
MK - Macedonia 1
MU - Mauritius 1
MW - Malawi 1
NC - Nuova Caledonia 1
NO - Norvegia 1
NP - Nepal 1
PR - Porto Rico 1
RS - Serbia 1
SI - Slovenia 1
SN - Senegal 1
SY - Repubblica araba siriana 1
TL - Timor Orientale 1
Totale 14.036
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Città #
Singapore 891
Ashburn 652
Southend 589
Fairfield 532
Chandler 416
Hefei 366
Bologna 349
Hong Kong 299
Santa Clara 293
Woodbridge 272
Seattle 254
Houston 227
Wilmington 209
Cambridge 202
Ann Arbor 173
Beijing 159
Dublin 156
Seoul 156
Princeton 152
Dong Ket 138
Abidjan 132
Jacksonville 100
Boardman 95
Ho Chi Minh City 89
Milan 85
Lomé 84
Nanjing 75
Hanoi 74
Los Angeles 65
Tokyo 63
Berlin 62
Westminster 60
Padova 59
Dallas 57
Sofia 52
New York 51
Frankfurt am Main 46
Amman 42
Bengaluru 42
Helsinki 42
Abeokuta 41
Turin 38
Jinan 37
Redmond 37
Bern 36
Falkenstein 35
Buffalo 34
Shenyang 34
Rome 32
São Paulo 31
Shanghai 29
Dearborn 28
Hebei 27
Tianjin 27
Changsha 26
Chicago 26
Genoa 26
Redondo Beach 26
Guangzhou 24
Munich 23
Florence 21
Brussels 20
Mülheim 20
San Diego 20
Stockholm 20
Bremen 19
Hyderabad 18
Nanchang 18
Saint Petersburg 18
Düsseldorf 16
Forlì 16
Leawood 16
Amsterdam 15
Lauterbourg 15
London 15
Toronto 15
Warsaw 15
Yubileyny 15
Hangzhou 14
Jalandhar 14
Vienna 14
Zhengzhou 14
Des Moines 13
Jakarta 13
Modena 13
Palermo 13
Phoenix 13
Johannesburg 12
Nuremberg 12
Redwood City 12
Boston 11
Brooklyn 11
Haikou 11
Haiphong 11
Medford 11
Montreal 11
Nürnberg 11
Verona 11
Atlanta 10
Belo Horizonte 10
Totale 9.054
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Nome #
A Focused Library of Psychotropic Analogues with Neuroprotective and Neuroregenerative Potential 362
A RAD51/BRCA2 small molecule inhibitor enhances the antineoplastic effect of the PARPi talazoparib in pancreatic cancer 319
Antioxidant Activity of Hydroxystilbene Derivatives in Homogeneous Solution 270
Enriching Proteolysis Targeting Chimeras with a Second Modality: When Two Are Better Than One 264
Rad51/Brca2 Disruptors Inhibit Homologous Recombination and Synergize with Olaparib in Pancreatic Cancer Cells 239
Synthetic Lethality in Pancreatic Cancer: Discovery of a New RAD51-BRCA2 Small Molecule Disruptor That Inhibits Homologous Recombination and Synergizes with Olaparib 239
A small chemical library of 2-aminoimidazole derivatives as BACE-1 inhibitors: structure-based design, synthesis, and biological evaluation 238
A journey through targeting BRCA2-RAD51 protein-protein interaction to establish synthetic lethality as paradigm for anticancer drug discovery 228
Insights into the activity of ARN24089, a new RAD51-BRCA2 disruptor that inhibits homologous recombination and achieves synthetic lethality in pancreatic cancer 226
Characterisation of bioactive compounds in wine by-products: toward the valorisation of sustainable resources 224
Computational design and discovery of "minimally structured" hERG blockers. 212
Berberine and its metabolites: Relationship between physicochemical properties and plasma levels after administration to human subjects 205
Arylsulphones: A Promising Class on Non-Nucleoside Antiviral Agents 197
SINTESI PARALLELA DI UNA COLLEZIONE DI PICCOLE MOLECOLE SIMIL-NATURALI MEDIANTE REAZIONE DOMINO KNOEVENAGEL/ DIELS-ALDER 191
Antiproliferative agents that interfere with the cell cycle at the G(1)-->S transition: further development and characterization of a small library of stilbene-derived compounds 191
New Horizons of Synthetic Lethality in Cancer: Current Development and Future Perspectives 185
Galloflavin, a new lactate dehydrogenase inhibitor, induces the death of human breast cancer cells with different glycolytic attitude by affecting distinct signaling pathways. 184
Identification and subsequent development of RAD51-BRCA2 disruptors through a fragment-based approach 183
Capitolo 2. Proprietà chimico-fisiche e attività biologica 182
Lactate dehydrogenase inhibitors can reverse inflammation induced changes in colon cancer cells 181
LDH inhibition impacts on heat shock response and induces senescence of hepatocellular carcinoma cells 176
Galloflavin (CAS 568-80-9), a novel inhibitor of lactate dehydrogenase. 175
An 19F NMR fragment-based approach for the discovery and development of BRCA2-RAD51 inhibitors to pursuit synthetic lethality in combination with PARP inhibition in pancreatic cancer 173
Benzimidazole derivatives as kinase inhibitors 173
Inhibition of Urease, a Ni-Enzyme: The Reactivity of a Key Thiol With Mono- and Di-Substituted Catechols Elucidated by Kinetic, Structural, and Theoretical Studies 173
Domino Knovenaegel/Diels-Alder Sequence Coupled to Suzuki Reaction: a Powerful Synthetic Platform for Chemical Biology 170
Multitarget Drug Design Strategy: Quinone–Tacrine Hybrids Designed To Block Amyloid-β Aggregation and To Exert Anticholinesterase and Antioxidant Effects 170
Lactate dehydrogenase inhibitors sensitize lymphoma cells to cisplatin without enhancing the drug effects on immortalized normal lymphocytes. 170
Lactate dehydrogenase inhibition affects homologous recombination repair independently of cell metabolic asset; implications for anticancer treatment 168
Synthetic Lethality Triggered by Combining Olaparib with BRCA2-Rad51 Disruptors 167
A natural-like synthetic small molecule impairs bcr-abl signaling cascades and induces megakaryocyte differentiation in erythroleukemia cells 166
Differential antiproliferative activity of new benzimidazole- 4,7-diones. 163
Parallel Synthesis, Evaluation, and Preliminary Structure-Activity Relationship of 2,5-Diamino-1,4-benzoquinones as a Novel Class of Bivalent Anti-Prion Compound. 162
TTAS a New Stilbene Derivative that Induces Apoptosis in Leishmania Infantum 160
Diaryl Urea: A Privileged Structure in Anticancer Agents 159
Domino Knoevenagel/Diels–Alder sequence coupled to Suzuki reaction: a valuable synthetic platform for chemical biology 158
Synthesis of natural urolithin M6, a galloflavin mimetic, as a potential inhibitor of lactate dehydrogenase A 158
Effects of trans-stilbene and terphenyl compounds on different strains of Leishmania and on cytokines production from infected macrophages 156
Hybrid Lipoic Acid Derivatives to Attack Prion Disease on Multiple Fronts 155
Novel antiproliferative chimeric compounds with marked histone deacetylase inhibitory activity. 155
Pterostilbene and 3'-hydroxypterostilbene are effective apoptosis-inducing agents in MDR and BCR-ABL-expressing leukemia cells 149
Identification of a terphenyl derivative that blocks the cell cycle in the G0-G1 phase and induces differentiation in leukemia cells. 149
Differential enantiomers activity of ARN24089 to achieve synthetic lethality in pancreatic cancer 141
Investigating synthetic lethality and PARP inhibitor resistance in pancreatic cancer through enantiomer differential activity 141
Preomic profile of BxPC-3 cells after treatment with BRC4 140
Non-ATP competitive protein kinase inhibitors 139
Nitrogen-containing heterocyclic quinones: a class of potential selective antitumor agents 139
Docking ligands on protein surfaces: the case study of prion protein. 138
Design and synthesis of RAD51-BRCA2 protein-protein interaction disruptors to trigger synthetic lethality with Olaparib in pancreatic cancer cells 135
Innovative Strategy toward Mutant CFTR Rescue in Cystic Fibrosis: Design and Synthesis of Thiadiazole Inhibitors of the E3 Ligase RNF5 135
The Mechanistic Understanding of RAD51 Defibrillation: A Critical Step in BRCA2-Mediated DNA Repair by Homologous Recombination 135
Synthesis and Pharmacology of 6-Substituted Benztropines: Discovery of Novel Dopamine Uptake Inhibitors Possessing Low Binding Affinity to the Dopamine Transporter 135
Targeting RNA degradation with small molecules: design and synthesis of selective RNA binders and development of ribonuclease targeting chimeras (RIBOTACs) 134
Polo-like kinases inhibitors 133
Identification of a Terphenyl-Based Small Molecule That Induces Differentiation in Leukemia Cells 131
Stilbene-based anticancer agents: Resveratrol analogues active toward HL60 leukemic cells with a non-specific phase mechanism. 130
Probing the binding sites and mechanisms of action of two human ether-a-go-go-related gene channel activators, 1,3-bis-(2-hydroxy-5-trifluoromethyl-phenyl)-urea (NS1643) and 2-[2-(3,4-dichloro-phenyl)-2,3-dihydro-1H-isoindol-5-ylamino]-nicotinic acid (PD307243) 128
Identification of RAD51-BRCA2 Inhibitors Using N-Acylhydrazone-Based Dynamic Combinatorial Chemistry 128
Suppression of human monocyte tissue factor induction by red wine phenolics and synthetic derivatives of resveratrol 125
Sequential Virtual Screening Approach to the Identification of Small Organic Molecules as Potential BACE-1 Inhibitors 123
Proteostasis Regulators in Cystic Fibrosis: Current Development and Future Perspectives 123
Dihydroquinoline pyrazoline-based compound as a new RAD51-BRCA2 protein-protein disruptor to trigger synthetic lethality in pancreatic cancer 122
Small molecule aurora kinases inhibitors 121
Combined analytical approaches to define biodistribution and biological activity of semi-synthetic berberrubine, the active metabolite of natural berberine 119
Thermal and catalytic reactions of ethyl diazopiruvate with [60]fullerene 118
Synthesis and Biological Evaluation of Novel 1'-Branched and Spiro-Nucleoside Analogues 116
Identification of biphenyl-based hybrid molecules able to decrease the intracellular level of Bcl-2 protein in Bcl-2 overexpressing leukemia cells 115
Heterocyclic and Phenyl Double-Bond-Locked Combretastatin Analogues Possessing Potent Apoptosis-Inducing Activity in HL60 and in MDR Cell Lines 115
Application of an “inhalation by design” approach to the identification and in-vitro evaluation of novel purine based PI3Kδ inhibitors 114
Identification of a 2,4-diaminopyrimidine scaffold targeting Trypanosoma brucei pteridine reductase 1 from the LIBRA compound library screening campaign 114
Identification and characterization of a terphenyl derivative blocking the G1-S transition in neoplastic cells 112
Studies on the Apoptotic Activity of Natural and Synthetic Retinoids: Discovery of a New Class of Synthetic Terphenyls That Potently Support Cell Growth and Inhibit Apoptosis in Neuronal and HL-60 Cells 107
Design and synthesis of RAD51-BRCA disruptors to inhibit homologous recombination and achieve synthetic lethality in cancer cells 103
Identification of N-acylhydrazone derivatives as novel lactate dehydrogenase A inhibitors 102
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Design and synthesis of RAD51-BRCA2 disruptors to inhibit homologous recombination and achieve synthetic lethality in pancreatic cancer cells 99
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Proteomic profile of BxPC-3 cells after treatment with BRC4 97
DESIGN OF LIGANDS WITH A HIGH AFFINITY TO PrPC 91
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Free-radical-mediated formation of trans-cardiolipin isomers, analytical approaches for lipidomics and consequences of the structural organization of membranes 87
Multiple Ligand Strategy in anticancer drug discovery 86
Design and synthesis of BRCA2-RAD51 disruptors to induce synthetic lethality in anticancer therapy 85
Multi-kinase inhibitors 83
Tacrine-resveratrol fused hybrids as multi-target-directed ligands against Alzheimer's disease 81
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Antiparasitic effect of stilbene and terphenyl compounds against trypanosoma cruzi parasites 79
A ligand-based virtual screening approach to identify small molecules as hERG channel activators 74
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Triggering RNA degradation with small molecules: development of RIBOnuclease TArgeting Chimeras (RIBOTACs) 73
The use of stilbene scaffold in medicinal chemistry and multi-target drug design 73
In vitro antileishmanial activity of trans-stilbene and terphenyl compounds 73
Synthetic small molecule Cdc25 phosphatases inhibitors 69
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RAD51 nuclear recruitment and inhibition towards innovative strategies against pancreatic cancer 61
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Irreversible protein kinase inhibitors 53
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Totale 14.170
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Categoria #
all - tutte 37.377
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 37.377
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021771 0 0 0 0 0 118 31 76 113 79 62 292
2021/20221.254 107 31 113 82 112 72 45 117 62 82 224 207
2022/20231.887 148 301 130 218 159 139 62 122 294 76 108 130
2023/2024973 98 102 49 94 64 126 68 68 29 79 100 96
2024/20252.867 137 338 181 158 466 163 221 115 99 278 186 525
2025/20263.317 545 650 552 666 628 276 0 0 0 0 0 0
Totale 14.303