CRIS Current Research Information System

ROBERTI, MARINELLA
 Distribuzione geografica
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Continente #
NA - Nord America 6.019
AS - Asia 5.693
EU - Europa 4.612
AF - Africa 393
SA - Sud America 381
OC - Oceania 14
Continente sconosciuto - Info sul continente non disponibili 1
Totale 17.113
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Nazione #
US - Stati Uniti d'America 5.903
CN - Cina 1.627
SG - Singapore 1.488
IT - Italia 1.437
VN - Vietnam 1.160
GB - Regno Unito 741
DE - Germania 564
HK - Hong Kong 381
SE - Svezia 350
IN - India 301
FR - Francia 296
BR - Brasile 294
KR - Corea 190
RU - Federazione Russa 190
UA - Ucraina 177
NL - Olanda 172
IE - Irlanda 159
CI - Costa d'Avorio 132
JP - Giappone 117
BD - Bangladesh 100
FI - Finlandia 86
TG - Togo 84
ZA - Sudafrica 72
CA - Canada 68
CH - Svizzera 65
EE - Estonia 57
BG - Bulgaria 55
JO - Giordania 47
PH - Filippine 45
ES - Italia 42
NG - Nigeria 42
TW - Taiwan 36
MX - Messico 31
PL - Polonia 31
AR - Argentina 30
TR - Turchia 30
AT - Austria 28
TH - Thailandia 28
BE - Belgio 26
HR - Croazia 26
ID - Indonesia 25
IR - Iran 24
DK - Danimarca 21
PK - Pakistan 19
EG - Egitto 18
SC - Seychelles 18
PT - Portogallo 17
IQ - Iraq 16
GR - Grecia 15
EC - Ecuador 14
AU - Australia 12
LT - Lituania 12
MA - Marocco 11
MT - Malta 10
CL - Cile 9
RO - Romania 9
SA - Arabia Saudita 9
AE - Emirati Arabi Uniti 8
CO - Colombia 8
CZ - Repubblica Ceca 7
PE - Perù 7
UZ - Uzbekistan 7
VE - Venezuela 7
MY - Malesia 6
PY - Paraguay 6
CR - Costa Rica 5
LB - Libano 5
CY - Cipro 4
DZ - Algeria 4
UY - Uruguay 4
HN - Honduras 3
IL - Israele 3
JM - Giamaica 3
KE - Kenya 3
NP - Nepal 3
SM - San Marino 3
BO - Bolivia 2
BY - Bielorussia 2
ET - Etiopia 2
GT - Guatemala 2
HU - Ungheria 2
KG - Kirghizistan 2
KH - Cambogia 2
LV - Lettonia 2
OM - Oman 2
SI - Slovenia 2
SN - Senegal 2
SY - Repubblica araba siriana 2
TN - Tunisia 2
AD - Andorra 1
AM - Armenia 1
BB - Barbados 1
BH - Bahrain 1
CG - Congo 1
CU - Cuba 1
CW - ???statistics.table.value.countryCode.CW??? 1
GE - Georgia 1
LI - Liechtenstein 1
LU - Lussemburgo 1
MD - Moldavia 1
Totale 17.100
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Città #
Singapore 1.054
Ashburn 728
Southend 589
Fairfield 532
Chandler 416
Bologna 409
Hefei 367
Hong Kong 347
Santa Clara 310
Woodbridge 272
Ho Chi Minh City 271
San Jose 268
Seattle 255
Hanoi 247
Houston 233
Wilmington 209
Cambridge 204
Beijing 180
Ann Arbor 173
Dublin 157
Seoul 156
Princeton 152
Dong Ket 138
Abidjan 132
Los Angeles 117
Lauterbourg 106
Jacksonville 102
Milan 101
Boardman 99
Tokyo 94
Lomé 84
Council Bluffs 82
Nanjing 80
New York 80
Helsinki 70
Berlin 63
Dallas 61
Westminster 60
Padova 59
Frankfurt am Main 55
Sofia 52
Rome 49
Amman 46
Buffalo 45
Da Nang 45
Bengaluru 43
Abeokuta 41
Turin 41
São Paulo 40
Jinan 38
Redmond 37
Shanghai 37
Bern 36
Falkenstein 35
Guangzhou 35
Genoa 34
Shenyang 34
Chicago 33
Haiphong 30
Tianjin 29
Dearborn 28
Florence 27
Hebei 27
Changsha 26
Redondo Beach 26
Munich 23
Johannesburg 21
London 21
San Diego 21
Brussels 20
Mülheim 20
Stockholm 20
Amsterdam 19
Bremen 19
Hyderabad 19
Montreal 19
Nanchang 19
Phoenix 19
Rimini 19
Saint Petersburg 18
Toronto 18
Copenhagen 17
Hangzhou 17
Palermo 17
Vienna 17
Atlanta 16
Biên Hòa 16
Düsseldorf 16
Forlì 16
Jalandhar 16
Leawood 16
Warsaw 16
Boston 15
Yubileyny 15
Zhengzhou 15
Des Moines 14
Jakarta 14
Modena 14
Nuremberg 14
Wuhan 14
Totale 10.636
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Nome #
A Focused Library of Psychotropic Analogues with Neuroprotective and Neuroregenerative Potential 440
A RAD51/BRCA2 small molecule inhibitor enhances the antineoplastic effect of the PARPi talazoparib in pancreatic cancer 359
Enriching Proteolysis Targeting Chimeras with a Second Modality: When Two Are Better Than One 307
Antioxidant Activity of Hydroxystilbene Derivatives in Homogeneous Solution 290
Characterisation of bioactive compounds in wine by-products: toward the valorisation of sustainable resources 279
Synthetic Lethality in Pancreatic Cancer: Discovery of a New RAD51-BRCA2 Small Molecule Disruptor That Inhibits Homologous Recombination and Synergizes with Olaparib 278
Rad51/Brca2 Disruptors Inhibit Homologous Recombination and Synergize with Olaparib in Pancreatic Cancer Cells 275
A journey through targeting BRCA2-RAD51 protein-protein interaction to establish synthetic lethality as paradigm for anticancer drug discovery 263
A small chemical library of 2-aminoimidazole derivatives as BACE-1 inhibitors: structure-based design, synthesis, and biological evaluation 261
Insights into the activity of ARN24089, a new RAD51-BRCA2 disruptor that inhibits homologous recombination and achieves synthetic lethality in pancreatic cancer 255
New Horizons of Synthetic Lethality in Cancer: Current Development and Future Perspectives 251
Investigating synthetic lethality and PARP inhibitor resistance in pancreatic cancer through enantiomer differential activity 244
Berberine and its metabolites: Relationship between physicochemical properties and plasma levels after administration to human subjects 243
Lactate dehydrogenase inhibition affects homologous recombination repair independently of cell metabolic asset; implications for anticancer treatment 238
Computational design and discovery of "minimally structured" hERG blockers. 237
Lactate dehydrogenase inhibitors can reverse inflammation induced changes in colon cancer cells 228
Preomic profile of BxPC-3 cells after treatment with BRC4 226
Targeting RNA degradation with small molecules: design and synthesis of selective RNA binders and development of ribonuclease targeting chimeras (RIBOTACs) 226
LDH inhibition impacts on heat shock response and induces senescence of hepatocellular carcinoma cells 220
Capitolo 2. Proprietà chimico-fisiche e attività biologica 218
Identification and subsequent development of RAD51-BRCA2 disruptors through a fragment-based approach 217
Arylsulphones: A Promising Class on Non-Nucleoside Antiviral Agents 216
An 19F NMR fragment-based approach for the discovery and development of BRCA2-RAD51 inhibitors to pursuit synthetic lethality in combination with PARP inhibition in pancreatic cancer 213
SINTESI PARALLELA DI UNA COLLEZIONE DI PICCOLE MOLECOLE SIMIL-NATURALI MEDIANTE REAZIONE DOMINO KNOEVENAGEL/ DIELS-ALDER 212
Galloflavin, a new lactate dehydrogenase inhibitor, induces the death of human breast cancer cells with different glycolytic attitude by affecting distinct signaling pathways. 211
Inhibition of Urease, a Ni-Enzyme: The Reactivity of a Key Thiol With Mono- and Di-Substituted Catechols Elucidated by Kinetic, Structural, and Theoretical Studies 210
Lactate dehydrogenase inhibitors sensitize lymphoma cells to cisplatin without enhancing the drug effects on immortalized normal lymphocytes. 207
Antiproliferative agents that interfere with the cell cycle at the G(1)-->S transition: further development and characterization of a small library of stilbene-derived compounds 204
Multitarget Drug Design Strategy: Quinone–Tacrine Hybrids Designed To Block Amyloid-β Aggregation and To Exert Anticholinesterase and Antioxidant Effects 203
Benzimidazole derivatives as kinase inhibitors 202
Galloflavin (CAS 568-80-9), a novel inhibitor of lactate dehydrogenase. 201
Differential enantiomers activity of ARN24089 to achieve synthetic lethality in pancreatic cancer 200
Synthetic Lethality Triggered by Combining Olaparib with BRCA2-Rad51 Disruptors 197
Synthesis of natural urolithin M6, a galloflavin mimetic, as a potential inhibitor of lactate dehydrogenase A 192
Design and synthesis of RAD51-BRCA2 protein-protein interaction disruptors to trigger synthetic lethality with Olaparib in pancreatic cancer cells 190
Domino Knovenaegel/Diels-Alder Sequence Coupled to Suzuki Reaction: a Powerful Synthetic Platform for Chemical Biology 189
Differential antiproliferative activity of new benzimidazole- 4,7-diones. 189
Diaryl Urea: A Privileged Structure in Anticancer Agents 187
Innovative Strategy toward Mutant CFTR Rescue in Cystic Fibrosis: Design and Synthesis of Thiadiazole Inhibitors of the E3 Ligase RNF5 181
A natural-like synthetic small molecule impairs bcr-abl signaling cascades and induces megakaryocyte differentiation in erythroleukemia cells 181
Domino Knoevenagel/Diels–Alder sequence coupled to Suzuki reaction: a valuable synthetic platform for chemical biology 180
Novel antiproliferative chimeric compounds with marked histone deacetylase inhibitory activity. 180
Design and synthesis of RAD51-BRCA2 disruptors to inhibit homologous recombination and achieve synthetic lethality in pancreatic cancer cells 180
TTAS a New Stilbene Derivative that Induces Apoptosis in Leishmania Infantum 179
Parallel Synthesis, Evaluation, and Preliminary Structure-Activity Relationship of 2,5-Diamino-1,4-benzoquinones as a Novel Class of Bivalent Anti-Prion Compound. 177
Effects of trans-stilbene and terphenyl compounds on different strains of Leishmania and on cytokines production from infected macrophages 172
Identification of a terphenyl derivative that blocks the cell cycle in the G0-G1 phase and induces differentiation in leukemia cells. 172
The Mechanistic Understanding of RAD51 Defibrillation: A Critical Step in BRCA2-Mediated DNA Repair by Homologous Recombination 171
Proteostasis Regulators in Cystic Fibrosis: Current Development and Future Perspectives 171
Hybrid Lipoic Acid Derivatives to Attack Prion Disease on Multiple Fronts 168
Dihydroquinoline pyrazoline-based compound as a new RAD51-BRCA2 protein-protein disruptor to trigger synthetic lethality in pancreatic cancer 164
Polo-like kinases inhibitors 163
Pterostilbene and 3'-hydroxypterostilbene are effective apoptosis-inducing agents in MDR and BCR-ABL-expressing leukemia cells 162
Identification of RAD51-BRCA2 Inhibitors Using N-Acylhydrazone-Based Dynamic Combinatorial Chemistry 159
Non-ATP competitive protein kinase inhibitors 156
Nitrogen-containing heterocyclic quinones: a class of potential selective antitumor agents 153
Combined analytical approaches to define biodistribution and biological activity of semi-synthetic berberrubine, the active metabolite of natural berberine 153
Docking ligands on protein surfaces: the case study of prion protein. 152
Identification of a Terphenyl-Based Small Molecule That Induces Differentiation in Leukemia Cells 149
Stilbene-based anticancer agents: Resveratrol analogues active toward HL60 leukemic cells with a non-specific phase mechanism. 147
Synthesis and Pharmacology of 6-Substituted Benztropines: Discovery of Novel Dopamine Uptake Inhibitors Possessing Low Binding Affinity to the Dopamine Transporter 145
Probing the binding sites and mechanisms of action of two human ether-a-go-go-related gene channel activators, 1,3-bis-(2-hydroxy-5-trifluoromethyl-phenyl)-urea (NS1643) and 2-[2-(3,4-dichloro-phenyl)-2,3-dihydro-1H-isoindol-5-ylamino]-nicotinic acid (PD307243) 143
Sequential Virtual Screening Approach to the Identification of Small Organic Molecules as Potential BACE-1 Inhibitors 142
Small molecule aurora kinases inhibitors 140
Suppression of human monocyte tissue factor induction by red wine phenolics and synthetic derivatives of resveratrol 139
Application of an “inhalation by design” approach to the identification and in-vitro evaluation of novel purine based PI3Kδ inhibitors 138
Identification of N-acylhydrazone derivatives as novel lactate dehydrogenase A inhibitors 138
Identification of a 2,4-diaminopyrimidine scaffold targeting Trypanosoma brucei pteridine reductase 1 from the LIBRA compound library screening campaign 134
Proteomic profile of BxPC-3 cells after treatment with BRC4 132
Thermal and catalytic reactions of ethyl diazopiruvate with [60]fullerene 130
Heterocyclic and Phenyl Double-Bond-Locked Combretastatin Analogues Possessing Potent Apoptosis-Inducing Activity in HL60 and in MDR Cell Lines 128
Identification and characterization of a terphenyl derivative blocking the G1-S transition in neoplastic cells 124
Design and synthesis of RAD51-BRCA disruptors to inhibit homologous recombination and achieve synthetic lethality in cancer cells 123
Identification of biphenyl-based hybrid molecules able to decrease the intracellular level of Bcl-2 protein in Bcl-2 overexpressing leukemia cells 123
Synthesis and Biological Evaluation of Novel 1'-Branched and Spiro-Nucleoside Analogues 121
Design and synthesis of BRCA2-RAD51 disruptors to induce synthetic lethality in anticancer therapy 119
Studies on the Apoptotic Activity of Natural and Synthetic Retinoids: Discovery of a New Class of Synthetic Terphenyls That Potently Support Cell Growth and Inhibit Apoptosis in Neuronal and HL-60 Cells 117
DESIGN OF LIGANDS WITH A HIGH AFFINITY TO PrPC 112
Multi-kinase inhibitors 112
Triggering RNA degradation with small molecules: development of RIBOnuclease TArgeting Chimeras (RIBOTACs) 110
Tacrine-resveratrol fused hybrids as multi-target-directed ligands against Alzheimer's disease 109
Targeting RAD51-BRCA2 Interaction to Enhance Synthetic Lethality with Olaparib in Pancreatic Cancer: Development of a Novel Phenyl Furan-Quinoline-Carboxylic Acid Series 108
Free-radical-mediated formation of trans-cardiolipin isomers, analytical approaches for lipidomics and consequences of the structural organization of membranes 105
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Multiple Ligand Strategy in anticancer drug discovery 97
Antiparasitic effect of stilbene and terphenyl compounds against trypanosoma cruzi parasites 97
The use of stilbene scaffold in medicinal chemistry and multi-target drug design 95
A ligand-based virtual screening approach to identify small molecules as hERG channel activators 94
In vitro antileishmanial activity of trans-stilbene and terphenyl compounds 90
RAD51 nuclear recruitment and inhibition towards innovative strategies against pancreatic cancer 88
Synthetic small molecule Cdc25 phosphatases inhibitors 88
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Design and synthesis of BRCA2-RAD51 disruptors to induce synthetic lethality in cancer treatment 85
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Design and synthesis of BRCA2-RAD51 disruptors to induce synthetic lethality in anticancer therapy 79
Application of Deep Learning to Predict the Persistence, Bioaccumulation, and Toxicity of Pharmaceuticals 77
Irreversible protein kinase inhibitors 74
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Totale 17.046
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Categoria #
all - tutte 44.566
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 44.566
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.254 107 31 113 82 112 72 45 117 62 82 224 207
2022/20231.887 148 301 130 218 159 139 62 122 294 76 108 130
2023/2024973 98 102 49 94 64 126 68 68 29 79 100 96
2024/20252.867 137 338 181 158 466 163 221 115 99 278 186 525
2025/20266.303 545 650 552 666 628 311 639 234 1.089 415 276 298
2026/2027115 115 0 0 0 0 0 0 0 0 0 0 0
Totale 17.404