SPAMPINATO, SANTI MARIO
 Distribuzione geografica
Continente #
NA - Nord America 9.106
AS - Asia 8.610
EU - Europa 6.980
AF - Africa 872
SA - Sud America 489
OC - Oceania 9
Continente sconosciuto - Info sul continente non disponibili 3
Totale 26.069
Nazione #
US - Stati Uniti d'America 8.994
SG - Singapore 2.538
CN - Cina 2.271
VN - Vietnam 1.955
GB - Regno Unito 1.632
IT - Italia 1.528
DE - Germania 917
HK - Hong Kong 600
SE - Svezia 519
FR - Francia 441
IN - India 396
UA - Ucraina 396
RU - Federazione Russa 388
BR - Brasile 335
TG - Togo 297
IE - Irlanda 296
CI - Costa d'Avorio 205
JP - Giappone 174
NL - Olanda 149
ZA - Sudafrica 148
FI - Finlandia 141
BG - Bulgaria 133
EE - Estonia 120
JO - Giordania 112
NG - Nigeria 108
KR - Corea 84
SC - Seychelles 76
HR - Croazia 74
TH - Thailandia 68
CA - Canada 67
PH - Filippine 62
AR - Argentina 60
ID - Indonesia 58
BE - Belgio 43
TR - Turchia 42
ES - Italia 37
BD - Bangladesh 35
CH - Svizzera 35
MX - Messico 33
PL - Polonia 30
IR - Iran 28
MY - Malesia 28
AT - Austria 26
IQ - Iraq 24
PK - Pakistan 24
EC - Ecuador 22
CL - Cile 19
TW - Taiwan 18
PE - Perù 17
SA - Arabia Saudita 15
UZ - Uzbekistan 15
LB - Libano 14
RO - Romania 14
IL - Israele 13
CO - Colombia 12
GR - Grecia 11
VE - Venezuela 11
HU - Ungheria 8
MA - Marocco 8
AE - Emirati Arabi Uniti 7
ET - Etiopia 7
KZ - Kazakistan 7
LT - Lituania 7
AU - Australia 6
DO - Repubblica Dominicana 6
PT - Portogallo 6
PY - Paraguay 6
TN - Tunisia 6
CZ - Repubblica Ceca 5
UY - Uruguay 5
AZ - Azerbaigian 4
KE - Kenya 4
LU - Lussemburgo 4
CR - Costa Rica 3
DK - Danimarca 3
EG - Egitto 3
EU - Europa 3
OM - Oman 3
PS - Palestinian Territory 3
RS - Serbia 3
SI - Slovenia 3
CY - Cipro 2
DZ - Algeria 2
GE - Georgia 2
GY - Guiana 2
JM - Giamaica 2
LK - Sri Lanka 2
LV - Lettonia 2
LY - Libia 2
MD - Moldavia 2
NO - Norvegia 2
NZ - Nuova Zelanda 2
SY - Repubblica araba siriana 2
AL - Albania 1
AM - Armenia 1
AO - Angola 1
BA - Bosnia-Erzegovina 1
BH - Bahrain 1
BY - Bielorussia 1
CG - Congo 1
Totale 26.059
Città #
Singapore 1.722
Southend 1.394
Ashburn 826
Chandler 738
Santa Clara 702
Fairfield 672
San Jose 593
Hong Kong 562
Ho Chi Minh City 474
Bologna 451
Hanoi 393
Princeton 346
Wilmington 334
Beijing 331
Lomé 297
Woodbridge 296
Seattle 295
Dublin 282
Houston 274
Jacksonville 263
Ann Arbor 262
Cambridge 249
Boardman 223
Abidjan 205
Nanjing 166
Hefei 163
Lauterbourg 160
Dong Ket 156
Tokyo 150
Westminster 148
Padova 134
Sofia 133
Los Angeles 123
Dallas 114
Amman 112
Berlin 111
Milan 106
Abeokuta 103
Helsinki 103
Jinan 89
Medford 81
Saint Petersburg 81
Shenyang 81
Frankfurt am Main 77
Munich 73
Buffalo 71
Bremen 70
Shanghai 70
New York 67
Redondo Beach 66
Hebei 63
Tianjin 59
Council Bluffs 56
Seoul 55
Guangzhou 54
Haiphong 54
Da Nang 53
Nanchang 53
Redmond 53
San Diego 50
Turin 50
Mülheim 49
Rome 49
Changsha 44
Zhengzhou 40
Bangkok 38
Brussels 38
Jakarta 38
São Paulo 37
Redwood City 36
Chicago 34
Des Moines 34
Turku 31
Falls Church 30
Mahé 30
Norwalk 30
Jiaxing 28
Shenzhen 28
Hangzhou 27
Orem 26
Haikou 24
London 24
Yubileyny 22
Atlanta 21
Biên Hòa 21
Toronto 21
Denver 20
Hải Dương 20
Moscow 20
Phoenix 20
Ningbo 19
Olalla 19
Shijiazhuang 19
Verona 19
Falkenstein 18
Johannesburg 18
Wuhan 18
Can Tho 17
Kunming 17
Rio de Janeiro 17
Totale 16.653
Nome #
Targeting integrins αvβ3 and α5β1 with new β-lactam derivatives 292
Synthesis and Biological Evaluation of Nonpeptide alpha-v-beta-3/alpha-5-beta-1 Integrin Dual Antagonists containing 5,6-Dihydropyridin-2-one Scaffolds 268
Leukocyte Integrin Antagonists as a Novel Option to Treat Dry Age-Related Macular Degeneration 268
Constraining Endomorphin-1 by β,α-Hybrid Dipeptide/Heterocycle Scaffolds: Identification of a Novel κ-Opioid Receptor Selective Partial Agonist 265
Dehydro-beta-proline Containing Alpha-4-beta-1 Integrin Antagonists: Stereochemical Recognition in Ligand-Receptor Interplay 263
Chitosan-based Polyelectrolyte Complexes for Nasal Drug Delivery 249
Could Dissecting the Molecular Framework of β-Lactam Integrin Ligands Enhance Selectivity? 243
Ligand Based Approach to L-Type Calcium Channel by Imidazo[2,1-b]thiazole-1,4-Dihydropyridines: from Heart Activity to Brain Affinity 237
5-aminomethyloxazolidine-2,4-dione hybrid α/β-dipeptide scaffolds as inductors of constrained conformations: Applications to the synthesis of integrin antagonists 232
New β-Lactam Derivatives Modulate Cell Adhesion and Signaling Mediated by RGD-Binding and Leukocyte Integrins 228
Nociceptin/orphanin FQ antagonizes lipopolysaccharide-stimulated proliferation, migration and inflammatory signaling in human glioblastoma U87 cells 228
α-linolenic acid-valproic acid conjugates: Toward single-molecule polypharmacology for multiple sclerosis 221
Endothelin-1 response to mental stress in early ischemic lesions of the extremities due to systemic sclerosis. 220
DS-70, a novel and potent α4 integrin antagonist, is an effective treatment for experimental allergic conjunctivitis in guinea pigs 217
Therapeutic Targeting of Eosinophil Adhesion and Accumulation in Allergic Conjunctivitis 215
β-Arrestin 2-mediated heterologous desensitization of IGF-IR by prolonged exposure of SH-SY5Y neuroblastoma cells to a mu opioid agonist 213
Diphenidol-related diamines as novel muscarinic M4 receptor antagonists 212
Opioid peptide response to spinal cord stimulation in chronic critical limb ischemia. 209
Biocompatibility and integrin-mediated adhesion of human osteoblasts to poly(DL-lactide-co-glycolide) copolymers 208
REST is up-regulated by epidermal growth factor in HeLa cells and inhibits apoptosis by influencing histone H3 acetylation 207
Transcription factor REST negatively influences the protein kinase C-dependent up-regulation of human mu-opioid receptor gene transcription 205
A novel family of minimalist opioid peptides deprived of the classic pharmacophores 203
Functional Selectivity and Antinociceptive Effects of a Novel KOPr Agonist 201
Antiangiogenic Effect of Dual/Selective α5β1/αvβ3 Integrin Antagonists Designed on Partially Modified Retro-Inverso Cyclotetrapeptide Mimetics 197
Ac-D-Trp-PheNH2 AND Ac-D-Trp-Phe-GlyNH2 - A NEW CLASS OF UNUSUAL OPIOID PEPTIDES 196
Oligonucleotidi antisenso anti pro-opiomelanocortina ipofisiaria e loro uso in campo medico per la prevenzione e la terapia della sindrome post-traumatica da stress (PTSD) 191
Integrin-mediated adhesive properties of neutrophils are reduced by hyperbaric oxygen therapy in patients with chronic non-healing wound 191
Design of α/β-hybrid peptide ligands of α4β1 integrin equipped with a linkable side chain for chemoselective biofunctionalization of microstructured materials 191
Plasma nociceptin/orphanin FQ levels in response to the hyperventilation test in healthy subjects. 187
Plasma brain natriuretic peptide at rest and after adenosine-induced myocardial ischemia in normotensive and essential hypertensive patients with suspected coronary artery disease. 186
Synthesis and evaluation of the affinity toward mu-opioid receptor of atypical, lipophilic ligands based on the sequence c[Tyr-Pro-Trp-Phe-Gly-]. 185
Imidazo[2,1-b]thiazole System: a Scaffold Endowing Dihydropyridines With Selective Cardiodepressant Activity 184
Agonist-Regulated Internalization and desensitization of the Human Nociceptin Receptor Expressed in CHO Cells 183
β-Endorphin in pressor response to hyperventilation in elderly patients with essential and secondary hypertension 182
Expression of the repressor element-1 silencing transcription factor (REST) is influenced by insulin-like growth factor-I in differentiating human neuroblastoma cells. 181
Antisense versus proopiomelanocortin mRNA reduces vascular risk in a murine model of type-2 diabetes following stress exposure in early post-natal life. 181
Synthesis and assay of retro-α4β1 integrin-targeting motifs 181
Investigation of the Interaction Between the Atypical Agonist c[YpwFG] and MOR 180
DESIGN AND SYNTHESIS OF OPIOID PEPTIDE ANALOGUES AND MIMETICS 179
Modulation of αvβ3- and α5β1-integrin-mediated adhesion by dehydro-β-amino acids containing peptidomimetics 179
Synthesis and pharmacological profile of a series of 1-substituted-2-carbonyl derivatives of diphenidol: novel M4 muscarinic receptor antagonists 178
Attività calcio modulatrice a livello cardiaco e vasale di derivati imidazo[2,1-b]tiazolici 178
Plasma nociceptin/orphanin FQ levels rise after spontaneous episodes of angina, but not during induced myocardial ischemia 177
The Inverse Type II β-Turn on D-Trp-Phe, a Pharmacophoric Motif for MOR Agonists. 176
A Blocking Group Scan Using a Spherical Organometallic Complex Identifies an Unprecedented Binding Mode with Potent Activity In Vitro and In Vivo for the Opioid Peptide Dermorphin 176
Contribution of alpha4beta1 integrin to the antiallergic effect of levocabastine 172
Administration of antisense oligonucleotide against pro-opiomelanocortin prevents enduring hormonal alterations induced by neonatal handling in male mice. 171
Opioid Activity Profiles of Oversimplified Peptides Lacking in the Protonable N-Terminus 171
Eosinophil as a cellular target of the ocular anti-allergic action of mapracorat, a novel selective glucocorticoid receptor agonist 170
Phase II drugs under investigation for allergic conjunctivitis 170
Pain and child: a translational hypothesis on the pathophysiology of a mild type-2 diabetes model. 168
Postnatal Stress Procedures Induce Long-Term Endocrine and Metabolic Alterations Involving Different Proopiomelanocortin-Derived Peptides 167
Cyclotetrapeptide Mimics based on a 13-Membered, Partially Modified Retro-Inverso Structure 166
mu-opioid receptor (MOR) expression and opioid-mediated intracellular signalling are altered in glial cells exposed to TNF-alpha 166
Sviluppo di un biosensore luminescente basato su una linea cellulare ricombinante di epatocarcinoma umano (HepG2) per la determinazione dell’attività di acidi biliarinaturali e sintetici 164
Agonist-regulated endocytosis and desensitization of the human nociceptin receptor 163
Brain-body metabolic programming and functional derangement in a type-2 diabetes model in male mice: the role exerted by opioid and HPA systems. 163
NEW PEPTIDOMIMETIC α4β1-INTEGRIN ANTAGONISTS FOR REDUCING INFLAMMATION AND ALLERGIC REACTIONS 163
A new generation of opioid peptidomimetics acting as central and/or peripheral analgesics 163
Role of nociceptin/orphanin FQ in thermoregulation 162
FXR activity modulation by bile acids and analogs assessed with a recombinant HepG2 cell-based luciferase assay. 161
Inhibition of cancer cell adhesion by heterochiral Pro-containing RGD mimetics. 161
Prodynorphin-Derived Opioid Peptides 159
Prodynorphin-derived peptides 159
New coumarin-based anti-inflammatory drug: putative antagonist of the integrins alpha(L)beta(2) and alpha(M)beta(2). 159
Plasma Brain Natriuretic Peptide at rest and after adenosine-induced myocardial ischemia in normotensive and essential hypertensive patients with suspected coronary artery disease 159
Synthesis and Conformational Analysis of Cyclotetrapeptide Mimetic beta-Turn Templates and Validation as 3D Scaffolds 158
Selective detection of α4β1 integrin (VLA-4)-expressing cells using peptide-functionalized nanostructured materials mimicking endothelial surfaces adjacent to inflammatory sites 158
BNP in normotesi ed ipertesi con sospetta insufficienza coronarica sottoposti a scintigrafia miocardica con adenosina 157
Development of new beta-lactam-based integrin ligands: Synthesis and Applications 157
Development of isoxazoline-containing peptidomimetics as dual alpha-v-beta-3 and alpha-5-beta-1 integrin ligands. 156
Design, Pharmacological Characterization, and Molecular Docking of Minimalist Peptidomimetic Antagonists of α4β1 Integrin 155
Analysis of the muscarinic receptor subtype mediating inhibition of the neurogenic contractions in rabbit isolated vas deferens by a series of polymethylene tetra-amines 153
Versatile Picklocks to Access All Opioid Receptors: Tuning the Selectivity and Functional Profile of the Cyclotetrapeptide c[Phe- d -Pro-Phe-Trp] (CJ-15,208) 152
Etiopathogenesis and pharmacological prevention of a type-2 diabetes model in male mice 152
Design and Pharmacological Characterization of α4β1 Integrin Cyclopeptide Agonists: Computational Investigation of Ligand Determinants for Agonism versus Antagonism 150
Dehydro-beta-amino acids as scaffolds for the preparation of alpha-v-beta-3, alpha-5-beta-1 and alpha-4-beta-1 integrin ligands 149
Regulation of ileal bile acid-binding protein expression in Caco-2 cells by ursodeoxycholic acid 149
Design and synthesis of Alpha-v-beta-3 and Alpha-5-beta-1 integrin ligands as delivery systems for fluorescent molecules 148
DETERMINATION OF THE BIOLOGICALLY ACTIVE STRUCTURE OF THE ATYPICAL MOR-LIGAND c[D-Asp-1-amide-beta-Ala-D-Trp-Phe] AND ANALOGUES BY NMR AND MOLECULAR DOCKING 147
TARGETING INTEGRINS WITH NEW BETA-LACTAM DERIVATIVES 146
Protective and worsening peripheral nociceptin/orphanin FQ receptor-mediated effect in a rat model of experimental colitis 145
Synthesis of Enantiomerically Pure alpha-v-beta-3 Integrin ligands Based on a 5,6-Dihydropyridin-2-one Scaffold. 145
Transcriptional activation of human mu-opioid receptor gene by insulin-like growth factor-I in neuronal cells is modulated by the transcription factor REST 145
Long-term intrathecal morphine and bupivacaine upregulate MOR gene expression in lymphocytes. 144
Post-natal stress-induced endocrine and metabolic alterations in mice at adulthood involve different pro-opiomelanocortin-derived peptides 143
Early post-natal life stress induces permanent adrenocorticotropin-dependent hypercortisolism in male mice 141
Protein aggregates and autophagy involvement in a family with a mutation in Z-band alternatively spliced PDZ-motif protein 141
Nandrolone decreases mu opioid receptor expression in SH-SY5Y human neuroblastoma cells 140
Mapracorat, a novel non-steroidal selective glucocorticoid receptor agonist for the treatment of allergic conjunctivitis 140
Development and characterization of novel EphB1 receptor antagonists. 140
Side chain effect in the modulation of αvβ3/α5β1 integrin activity via clickable isoxazoline-RGD-mimetics: development of molecular delivery systems 136
Enhanced brain performance in mice following postnatal stress 135
Septal grafts restore cognitive abilities and amyloid precursor protein metabolism. 131
Novel Antagonist targeting EphB1 receptor 131
Expression of the transcription factor REST at different stages of neuronal differentiation: contribution of PKC and WNT/-catenin signaling 130
Selective Integrin Ligands Promote Cell Internalization of the Antineoplastic Agent Fluorouracil 130
Peptidomimetic Scaffolds for the Discovery of New Bioactive Compounds. Cyclotetrapeptide Analogues Based on a 13-Membered, Partially Modified Retro-Inverso Structure. Applications to the synthesis of Cancer Cell Adhesion Inhibitors 129
Inhibition of Toll-like Receptor 4 (TLR4)-induced NF-kB activation by NOP is lost in human glioblastoma cells chronically exposed to LPS. 129
Interactions between atypical opioid agonists and MOR 128
Totale 17.690
Categoria #
all - tutte 71.177
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 71.177


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021671 0 0 0 0 0 0 0 0 0 104 142 425
2021/20222.987 351 156 160 133 277 200 99 278 117 175 479 562
2022/20233.682 330 543 175 439 295 300 197 190 744 69 245 155
2023/20241.159 64 179 69 109 80 266 63 103 47 58 63 58
2024/20254.143 181 583 405 277 948 223 300 96 28 193 105 804
2025/20267.921 574 740 724 634 1.040 482 971 402 1.782 572 0 0
Totale 26.503