CRIS Current Research Information System

SPAMPINATO, SANTI MARIO
 Distribuzione geografica
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Continente #
NA - Nord America 8.114
EU - Europa 6.595
AS - Asia 6.402
AF - Africa 837
SA - Sud America 435
OC - Oceania 9
Continente sconosciuto - Info sul continente non disponibili 3
Totale 22.395
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Nazione #
US - Stati Uniti d'America 8.034
SG - Singapore 2.222
CN - Cina 1.983
GB - Regno Unito 1.613
IT - Italia 1.473
DE - Germania 892
VN - Vietnam 827
HK - Hong Kong 550
SE - Svezia 517
UA - Ucraina 393
RU - Federazione Russa 383
IN - India 354
BR - Brasile 307
TG - Togo 297
FR - Francia 276
IE - Irlanda 268
CI - Costa d'Avorio 205
NL - Olanda 141
ZA - Sudafrica 137
BG - Bulgaria 133
EE - Estonia 120
JO - Giordania 111
NG - Nigeria 105
JP - Giappone 104
FI - Finlandia 88
SC - Seychelles 76
HR - Croazia 73
KR - Corea 60
AR - Argentina 58
CA - Canada 49
BE - Belgio 43
ID - Indonesia 40
CH - Svizzera 35
ES - Italia 32
IR - Iran 28
TR - Turchia 28
PL - Polonia 27
AT - Austria 26
MX - Messico 25
EC - Ecuador 17
CL - Cile 15
LB - Libano 14
PE - Perù 14
IL - Israele 13
RO - Romania 13
BD - Bangladesh 12
PK - Pakistan 12
GR - Grecia 9
CO - Colombia 8
HU - Ungheria 7
LT - Lituania 7
MY - Malesia 7
VE - Venezuela 7
AE - Emirati Arabi Uniti 6
AU - Australia 6
DO - Repubblica Dominicana 6
KZ - Kazakistan 6
UZ - Uzbekistan 6
MA - Marocco 5
PY - Paraguay 5
LU - Lussemburgo 4
CZ - Repubblica Ceca 3
DK - Danimarca 3
EU - Europa 3
PT - Portogallo 3
SA - Arabia Saudita 3
TN - Tunisia 3
AZ - Azerbaigian 2
EG - Egitto 2
ET - Etiopia 2
GY - Guiana 2
IQ - Iraq 2
KE - Kenya 2
LK - Sri Lanka 2
LV - Lettonia 2
MD - Moldavia 2
NO - Norvegia 2
NZ - Nuova Zelanda 2
TH - Thailandia 2
UY - Uruguay 2
AL - Albania 1
AM - Armenia 1
BA - Bosnia-Erzegovina 1
BH - Bahrain 1
BY - Bielorussia 1
CY - Cipro 1
DZ - Algeria 1
GE - Georgia 1
KH - Cambogia 1
KI - Kiribati 1
LY - Libia 1
MK - Macedonia 1
MM - Myanmar 1
MW - Malawi 1
OM - Oman 1
RS - Serbia 1
SI - Slovenia 1
SK - Slovacchia (Repubblica Slovacca) 1
SY - Repubblica araba siriana 1
Totale 22.395
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Città #
Singapore 1.455
Southend 1.394
Ashburn 761
Chandler 738
Santa Clara 694
Fairfield 672
Hong Kong 544
Bologna 422
Princeton 346
Wilmington 334
Beijing 313
Lomé 297
Woodbridge 296
Seattle 294
Houston 269
Ann Arbor 262
Dublin 262
Jacksonville 262
Cambridge 249
Boardman 223
Abidjan 205
Ho Chi Minh City 176
Hefei 162
Nanjing 162
Dong Ket 156
Westminster 148
Padova 134
Sofia 133
Hanoi 114
Los Angeles 113
Amman 111
Berlin 111
Dallas 108
Milan 106
Abeokuta 103
Tokyo 99
Jinan 88
Medford 81
Saint Petersburg 81
Shenyang 81
Munich 73
Bremen 70
Buffalo 68
Redondo Beach 66
Hebei 63
New York 59
Shanghai 57
Frankfurt am Main 55
Tianjin 54
Nanchang 53
Redmond 53
Seoul 53
Helsinki 51
Turin 50
Mülheim 49
San Diego 49
Rome 47
Changsha 40
Guangzhou 40
Brussels 38
Zhengzhou 38
Redwood City 36
Des Moines 32
São Paulo 32
Turku 31
Chicago 30
Falls Church 30
Mahé 30
Norwalk 30
Jiaxing 28
Haikou 24
Hangzhou 24
Jakarta 23
Shenzhen 23
Yubileyny 22
London 20
Moscow 20
Toronto 20
Ningbo 19
Olalla 19
Verona 19
Falkenstein 18
Phoenix 18
Shijiazhuang 18
Rio de Janeiro 17
Taiyuan 16
Wuhan 16
Xi'an 16
Bühl 15
Modena 15
Nuremberg 15
Taizhou 15
Bern 14
Brooklyn 14
Denver 14
Parma 14
Bengaluru 13
Biên Hòa 13
Kunming 13
Manchester 13
Totale 14.484
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Nome #
Targeting integrins αvβ3 and α5β1 with new β-lactam derivatives 254
Synthesis and Biological Evaluation of Nonpeptide alpha-v-beta-3/alpha-5-beta-1 Integrin Dual Antagonists containing 5,6-Dihydropyridin-2-one Scaffolds 249
Leukocyte Integrin Antagonists as a Novel Option to Treat Dry Age-Related Macular Degeneration 232
Chitosan-based Polyelectrolyte Complexes for Nasal Drug Delivery 231
Dehydro-beta-proline Containing Alpha-4-beta-1 Integrin Antagonists: Stereochemical Recognition in Ligand-Receptor Interplay 229
Constraining Endomorphin-1 by β,α-Hybrid Dipeptide/Heterocycle Scaffolds: Identification of a Novel κ-Opioid Receptor Selective Partial Agonist 223
New β-Lactam Derivatives Modulate Cell Adhesion and Signaling Mediated by RGD-Binding and Leukocyte Integrins 207
Ligand Based Approach to L-Type Calcium Channel by Imidazo[2,1-b]thiazole-1,4-Dihydropyridines: from Heart Activity to Brain Affinity 206
5-aminomethyloxazolidine-2,4-dione hybrid α/β-dipeptide scaffolds as inductors of constrained conformations: Applications to the synthesis of integrin antagonists 205
Therapeutic Targeting of Eosinophil Adhesion and Accumulation in Allergic Conjunctivitis 198
β-Arrestin 2-mediated heterologous desensitization of IGF-IR by prolonged exposure of SH-SY5Y neuroblastoma cells to a mu opioid agonist 197
Diphenidol-related diamines as novel muscarinic M4 receptor antagonists 194
DS-70, a novel and potent α4 integrin antagonist, is an effective treatment for experimental allergic conjunctivitis in guinea pigs 192
Endothelin-1 response to mental stress in early ischemic lesions of the extremities due to systemic sclerosis. 191
REST is up-regulated by epidermal growth factor in HeLa cells and inhibits apoptosis by influencing histone H3 acetylation 191
Opioid peptide response to spinal cord stimulation in chronic critical limb ischemia. 190
A novel family of minimalist opioid peptides deprived of the classic pharmacophores 190
Biocompatibility and integrin-mediated adhesion of human osteoblasts to poly(DL-lactide-co-glycolide) copolymers 189
Transcription factor REST negatively influences the protein kinase C-dependent up-regulation of human mu-opioid receptor gene transcription 188
α-linolenic acid-valproic acid conjugates: Toward single-molecule polypharmacology for multiple sclerosis 187
Could Dissecting the Molecular Framework of β-Lactam Integrin Ligands Enhance Selectivity? 186
Nociceptin/orphanin FQ antagonizes lipopolysaccharide-stimulated proliferation, migration and inflammatory signaling in human glioblastoma U87 cells 185
Ac-D-Trp-PheNH2 AND Ac-D-Trp-Phe-GlyNH2 - A NEW CLASS OF UNUSUAL OPIOID PEPTIDES 182
Antiangiogenic Effect of Dual/Selective α5β1/αvβ3 Integrin Antagonists Designed on Partially Modified Retro-Inverso Cyclotetrapeptide Mimetics 179
Functional Selectivity and Antinociceptive Effects of a Novel KOPr Agonist 173
Synthesis and evaluation of the affinity toward mu-opioid receptor of atypical, lipophilic ligands based on the sequence c[Tyr-Pro-Trp-Phe-Gly-]. 171
Plasma brain natriuretic peptide at rest and after adenosine-induced myocardial ischemia in normotensive and essential hypertensive patients with suspected coronary artery disease. 169
Imidazo[2,1-b]thiazole System: a Scaffold Endowing Dihydropyridines With Selective Cardiodepressant Activity 168
Expression of the repressor element-1 silencing transcription factor (REST) is influenced by insulin-like growth factor-I in differentiating human neuroblastoma cells. 165
A Blocking Group Scan Using a Spherical Organometallic Complex Identifies an Unprecedented Binding Mode with Potent Activity In Vitro and In Vivo for the Opioid Peptide Dermorphin 165
Oligonucleotidi antisenso anti pro-opiomelanocortina ipofisiaria e loro uso in campo medico per la prevenzione e la terapia della sindrome post-traumatica da stress (PTSD) 164
Pain and child: a translational hypothesis on the pathophysiology of a mild type-2 diabetes model. 162
Attività calcio modulatrice a livello cardiaco e vasale di derivati imidazo[2,1-b]tiazolici 162
β-Endorphin in pressor response to hyperventilation in elderly patients with essential and secondary hypertension 162
Plasma nociceptin/orphanin FQ levels in response to the hyperventilation test in healthy subjects. 161
Antisense versus proopiomelanocortin mRNA reduces vascular risk in a murine model of type-2 diabetes following stress exposure in early post-natal life. 161
Agonist-Regulated Internalization and desensitization of the Human Nociceptin Receptor Expressed in CHO Cells 159
Administration of antisense oligonucleotide against pro-opiomelanocortin prevents enduring hormonal alterations induced by neonatal handling in male mice. 159
Synthesis and pharmacological profile of a series of 1-substituted-2-carbonyl derivatives of diphenidol: novel M4 muscarinic receptor antagonists 159
Postnatal Stress Procedures Induce Long-Term Endocrine and Metabolic Alterations Involving Different Proopiomelanocortin-Derived Peptides 158
Design of α/β-hybrid peptide ligands of α4β1 integrin equipped with a linkable side chain for chemoselective biofunctionalization of microstructured materials 158
The Inverse Type II β-Turn on D-Trp-Phe, a Pharmacophoric Motif for MOR Agonists. 157
Opioid Activity Profiles of Oversimplified Peptides Lacking in the Protonable N-Terminus 157
DESIGN AND SYNTHESIS OF OPIOID PEPTIDE ANALOGUES AND MIMETICS 157
Phase II drugs under investigation for allergic conjunctivitis 156
Integrin-mediated adhesive properties of neutrophils are reduced by hyperbaric oxygen therapy in patients with chronic non-healing wound 156
Contribution of alpha4beta1 integrin to the antiallergic effect of levocabastine 155
Plasma nociceptin/orphanin FQ levels rise after spontaneous episodes of angina, but not during induced myocardial ischemia 154
Synthesis and assay of retro-α4β1 integrin-targeting motifs 154
Modulation of αvβ3- and α5β1-integrin-mediated adhesion by dehydro-β-amino acids containing peptidomimetics 154
Investigation of the Interaction Between the Atypical Agonist c[YpwFG] and MOR 152
Inhibition of cancer cell adhesion by heterochiral Pro-containing RGD mimetics. 149
A new generation of opioid peptidomimetics acting as central and/or peripheral analgesics 148
FXR activity modulation by bile acids and analogs assessed with a recombinant HepG2 cell-based luciferase assay. 147
Sviluppo di un biosensore luminescente basato su una linea cellulare ricombinante di epatocarcinoma umano (HepG2) per la determinazione dell’attività di acidi biliarinaturali e sintetici 147
Prodynorphin-Derived Opioid Peptides 146
Prodynorphin-derived peptides 146
Eosinophil as a cellular target of the ocular anti-allergic action of mapracorat, a novel selective glucocorticoid receptor agonist 146
Brain-body metabolic programming and functional derangement in a type-2 diabetes model in male mice: the role exerted by opioid and HPA systems. 145
Agonist-regulated endocytosis and desensitization of the human nociceptin receptor 144
Cyclotetrapeptide Mimics based on a 13-Membered, Partially Modified Retro-Inverso Structure 144
mu-opioid receptor (MOR) expression and opioid-mediated intracellular signalling are altered in glial cells exposed to TNF-alpha 143
New coumarin-based anti-inflammatory drug: putative antagonist of the integrins alpha(L)beta(2) and alpha(M)beta(2). 142
Role of nociceptin/orphanin FQ in thermoregulation 141
Etiopathogenesis and pharmacological prevention of a type-2 diabetes model in male mice 140
Long-term intrathecal morphine and bupivacaine upregulate MOR gene expression in lymphocytes. 137
Development of isoxazoline-containing peptidomimetics as dual alpha-v-beta-3 and alpha-5-beta-1 integrin ligands. 136
Analysis of the muscarinic receptor subtype mediating inhibition of the neurogenic contractions in rabbit isolated vas deferens by a series of polymethylene tetra-amines 135
Regulation of ileal bile acid-binding protein expression in Caco-2 cells by ursodeoxycholic acid 135
Post-natal stress-induced endocrine and metabolic alterations in mice at adulthood involve different pro-opiomelanocortin-derived peptides 134
Plasma Brain Natriuretic Peptide at rest and after adenosine-induced myocardial ischemia in normotensive and essential hypertensive patients with suspected coronary artery disease 134
Dehydro-beta-amino acids as scaffolds for the preparation of alpha-v-beta-3, alpha-5-beta-1 and alpha-4-beta-1 integrin ligands 132
NEW PEPTIDOMIMETIC α4β1-INTEGRIN ANTAGONISTS FOR REDUCING INFLAMMATION AND ALLERGIC REACTIONS 132
BNP in normotesi ed ipertesi con sospetta insufficienza coronarica sottoposti a scintigrafia miocardica con adenosina 132
DETERMINATION OF THE BIOLOGICALLY ACTIVE STRUCTURE OF THE ATYPICAL MOR-LIGAND c[D-Asp-1-amide-beta-Ala-D-Trp-Phe] AND ANALOGUES BY NMR AND MOLECULAR DOCKING 132
Protective and worsening peripheral nociceptin/orphanin FQ receptor-mediated effect in a rat model of experimental colitis 132
Versatile Picklocks to Access All Opioid Receptors: Tuning the Selectivity and Functional Profile of the Cyclotetrapeptide c[Phe- d -Pro-Phe-Trp] (CJ-15,208) 131
Synthesis and Conformational Analysis of Cyclotetrapeptide Mimetic beta-Turn Templates and Validation as 3D Scaffolds 131
Development of new beta-lactam-based integrin ligands: Synthesis and Applications 130
Design and synthesis of Alpha-v-beta-3 and Alpha-5-beta-1 integrin ligands as delivery systems for fluorescent molecules 128
Transcriptional activation of human mu-opioid receptor gene by insulin-like growth factor-I in neuronal cells is modulated by the transcription factor REST 128
Selective detection of α4β1 integrin (VLA-4)-expressing cells using peptide-functionalized nanostructured materials mimicking endothelial surfaces adjacent to inflammatory sites 128
Design and Pharmacological Characterization of α4β1 Integrin Cyclopeptide Agonists: Computational Investigation of Ligand Determinants for Agonism versus Antagonism 127
Enhanced brain performance in mice following postnatal stress 127
Septal grafts restore cognitive abilities and amyloid precursor protein metabolism. 126
Design, Pharmacological Characterization, and Molecular Docking of Minimalist Peptidomimetic Antagonists of α4β1 Integrin 125
Nandrolone decreases mu opioid receptor expression in SH-SY5Y human neuroblastoma cells 125
Synthesis of Enantiomerically Pure alpha-v-beta-3 Integrin ligands Based on a 5,6-Dihydropyridin-2-one Scaffold. 124
Protein aggregates and autophagy involvement in a family with a mutation in Z-band alternatively spliced PDZ-motif protein 124
Mapracorat, a novel non-steroidal selective glucocorticoid receptor agonist for the treatment of allergic conjunctivitis 118
Early post-natal life stress induces permanent adrenocorticotropin-dependent hypercortisolism in male mice 117
TARGETING INTEGRINS WITH NEW BETA-LACTAM DERIVATIVES 116
Inhibition of Toll-like Receptor 4 (TLR4)-induced NF-kB activation by NOP is lost in human glioblastoma cells chronically exposed to LPS. 114
Interactions between atypical opioid agonists and MOR 114
Investigation on MOR receptor activation by atypical mechanisms 111
Overview of genetic analysis of human opioid receptors 111
Development and characterization of novel EphB1 receptor antagonists. 111
Repeated mild postnatal stress in mice:persistence of effects in adult animals. 110
Expression of the transcription factor REST at different stages of neuronal differentiation: contribution of PKC and WNT/-catenin signaling 110
Biphasic modulation of mu-opoid receptor (MOR) transcription by nociceptin in neuroblastoma cells co-expressing MOR and NOP receptors 108
Totale 15.596
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Categoria #
all - tutte 65.726
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 65.726
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20211.053 0 0 0 0 0 0 85 136 161 104 142 425
2021/20222.987 351 156 160 133 277 200 99 278 117 175 479 562
2022/20233.682 330 543 175 439 295 300 197 190 744 69 245 155
2023/20241.159 64 179 69 109 80 266 63 103 47 58 63 58
2024/20254.143 181 583 405 277 948 223 300 96 28 193 105 804
2025/20264.205 574 740 724 634 1.040 482 11 0 0 0 0 0
Totale 22.787