CRIS Current Research Information System

SPAMPINATO, SANTI MARIO
 Distribuzione geografica
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Continente #
NA - Nord America 9.600
AS - Asia 8.711
EU - Europa 7.052
AF - Africa 872
SA - Sud America 503
OC - Oceania 10
Continente sconosciuto - Info sul continente non disponibili 3
Totale 26.751
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Nazione #
US - Stati Uniti d'America 9.458
SG - Singapore 2.563
CN - Cina 2.288
VN - Vietnam 1.957
GB - Regno Unito 1.633
IT - Italia 1.596
DE - Germania 917
HK - Hong Kong 614
SE - Svezia 519
FR - Francia 442
IN - India 397
UA - Ucraina 396
RU - Federazione Russa 388
BR - Brasile 347
TG - Togo 297
IE - Irlanda 296
CI - Costa d'Avorio 205
JP - Giappone 174
NL - Olanda 149
ZA - Sudafrica 148
FI - Finlandia 141
BG - Bulgaria 133
EE - Estonia 120
JO - Giordania 112
NG - Nigeria 108
KR - Corea 84
CA - Canada 79
SC - Seychelles 76
BD - Bangladesh 75
HR - Croazia 74
TH - Thailandia 68
PH - Filippine 62
AR - Argentina 60
ID - Indonesia 58
BE - Belgio 43
MX - Messico 42
TR - Turchia 42
ES - Italia 38
CH - Svizzera 36
PL - Polonia 30
IR - Iran 28
MY - Malesia 28
AT - Austria 26
PK - Pakistan 25
IQ - Iraq 24
EC - Ecuador 22
CL - Cile 19
PE - Perù 18
TW - Taiwan 18
SA - Arabia Saudita 16
UZ - Uzbekistan 15
LB - Libano 14
RO - Romania 14
CO - Colombia 13
IL - Israele 13
GR - Grecia 11
VE - Venezuela 11
HU - Ungheria 8
MA - Marocco 8
AE - Emirati Arabi Uniti 7
AU - Australia 7
ET - Etiopia 7
KZ - Kazakistan 7
LT - Lituania 7
CR - Costa Rica 6
DO - Repubblica Dominicana 6
PT - Portogallo 6
PY - Paraguay 6
TN - Tunisia 6
CZ - Repubblica Ceca 5
UY - Uruguay 5
AZ - Azerbaigian 4
KE - Kenya 4
LU - Lussemburgo 4
DK - Danimarca 3
EG - Egitto 3
EU - Europa 3
OM - Oman 3
PS - Palestinian Territory 3
RS - Serbia 3
SI - Slovenia 3
TT - Trinidad e Tobago 3
CY - Cipro 2
DZ - Algeria 2
GE - Georgia 2
GY - Guiana 2
JM - Giamaica 2
LK - Sri Lanka 2
LV - Lettonia 2
LY - Libia 2
MD - Moldavia 2
NO - Norvegia 2
NZ - Nuova Zelanda 2
SV - El Salvador 2
SY - Repubblica araba siriana 2
AL - Albania 1
AM - Armenia 1
AO - Angola 1
BA - Bosnia-Erzegovina 1
BH - Bahrain 1
Totale 26.738
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Città #
Singapore 1.743
Southend 1.394
Ashburn 862
Chandler 738
San Jose 712
Santa Clara 709
Fairfield 672
Hong Kong 576
Ho Chi Minh City 474
Bologna 463
Hanoi 395
Princeton 346
Beijing 340
Wilmington 334
Lomé 297
Seattle 296
Woodbridge 296
Dublin 282
Houston 275
Jacksonville 263
Ann Arbor 262
Cambridge 249
Boardman 229
Abidjan 205
Nanjing 166
Hefei 163
Lauterbourg 160
Dong Ket 156
Tokyo 150
Westminster 149
Los Angeles 137
Padova 134
Sofia 133
Dallas 121
Council Bluffs 116
Amman 112
Berlin 111
Milan 110
Abeokuta 103
Helsinki 103
Jinan 89
Medford 81
Saint Petersburg 81
Shenyang 81
Frankfurt am Main 77
New York 77
Buffalo 76
Shanghai 74
Munich 73
Bremen 70
Redondo Beach 66
Hebei 63
Tianjin 59
Seoul 55
Guangzhou 54
Haiphong 54
Rome 54
Da Nang 53
Nanchang 53
Redmond 53
Turin 52
San Diego 50
Mülheim 49
Changsha 44
São Paulo 42
Chicago 40
Zhengzhou 40
Bangkok 38
Brussels 38
Jakarta 38
Redwood City 36
Des Moines 34
Turku 31
Falls Church 30
Mahé 30
Norwalk 30
Orem 29
Jiaxing 28
Modena 28
Shenzhen 28
Hangzhou 27
London 26
Atlanta 25
Haikou 24
Phoenix 23
Toronto 22
Yubileyny 22
Biên Hòa 21
Denver 21
Hải Dương 20
Moscow 20
Brooklyn 19
Mexico City 19
Ningbo 19
Olalla 19
Shijiazhuang 19
Verona 19
Falkenstein 18
Johannesburg 18
Rio de Janeiro 18
Totale 17.033
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Nome #
Targeting integrins αvβ3 and α5β1 with new β-lactam derivatives 295
Synthesis and Biological Evaluation of Nonpeptide alpha-v-beta-3/alpha-5-beta-1 Integrin Dual Antagonists containing 5,6-Dihydropyridin-2-one Scaffolds 278
Leukocyte Integrin Antagonists as a Novel Option to Treat Dry Age-Related Macular Degeneration 276
Constraining Endomorphin-1 by β,α-Hybrid Dipeptide/Heterocycle Scaffolds: Identification of a Novel κ-Opioid Receptor Selective Partial Agonist 270
Dehydro-beta-proline Containing Alpha-4-beta-1 Integrin Antagonists: Stereochemical Recognition in Ligand-Receptor Interplay 268
Chitosan-based Polyelectrolyte Complexes for Nasal Drug Delivery 252
Could Dissecting the Molecular Framework of β-Lactam Integrin Ligands Enhance Selectivity? 248
Ligand Based Approach to L-Type Calcium Channel by Imidazo[2,1-b]thiazole-1,4-Dihydropyridines: from Heart Activity to Brain Affinity 242
5-aminomethyloxazolidine-2,4-dione hybrid α/β-dipeptide scaffolds as inductors of constrained conformations: Applications to the synthesis of integrin antagonists 237
New β-Lactam Derivatives Modulate Cell Adhesion and Signaling Mediated by RGD-Binding and Leukocyte Integrins 236
Nociceptin/orphanin FQ antagonizes lipopolysaccharide-stimulated proliferation, migration and inflammatory signaling in human glioblastoma U87 cells 230
α-linolenic acid-valproic acid conjugates: Toward single-molecule polypharmacology for multiple sclerosis 224
Endothelin-1 response to mental stress in early ischemic lesions of the extremities due to systemic sclerosis. 223
Diphenidol-related diamines as novel muscarinic M4 receptor antagonists 220
DS-70, a novel and potent α4 integrin antagonist, is an effective treatment for experimental allergic conjunctivitis in guinea pigs 219
Therapeutic Targeting of Eosinophil Adhesion and Accumulation in Allergic Conjunctivitis 218
β-Arrestin 2-mediated heterologous desensitization of IGF-IR by prolonged exposure of SH-SY5Y neuroblastoma cells to a mu opioid agonist 215
Opioid peptide response to spinal cord stimulation in chronic critical limb ischemia. 214
Biocompatibility and integrin-mediated adhesion of human osteoblasts to poly(DL-lactide-co-glycolide) copolymers 214
REST is up-regulated by epidermal growth factor in HeLa cells and inhibits apoptosis by influencing histone H3 acetylation 213
Transcription factor REST negatively influences the protein kinase C-dependent up-regulation of human mu-opioid receptor gene transcription 208
A novel family of minimalist opioid peptides deprived of the classic pharmacophores 206
Functional Selectivity and Antinociceptive Effects of a Novel KOPr Agonist 206
Antiangiogenic Effect of Dual/Selective α5β1/αvβ3 Integrin Antagonists Designed on Partially Modified Retro-Inverso Cyclotetrapeptide Mimetics 205
Ac-D-Trp-PheNH2 AND Ac-D-Trp-Phe-GlyNH2 - A NEW CLASS OF UNUSUAL OPIOID PEPTIDES 201
Oligonucleotidi antisenso anti pro-opiomelanocortina ipofisiaria e loro uso in campo medico per la prevenzione e la terapia della sindrome post-traumatica da stress (PTSD) 199
Integrin-mediated adhesive properties of neutrophils are reduced by hyperbaric oxygen therapy in patients with chronic non-healing wound 197
Design of α/β-hybrid peptide ligands of α4β1 integrin equipped with a linkable side chain for chemoselective biofunctionalization of microstructured materials 197
Plasma brain natriuretic peptide at rest and after adenosine-induced myocardial ischemia in normotensive and essential hypertensive patients with suspected coronary artery disease. 196
Plasma nociceptin/orphanin FQ levels in response to the hyperventilation test in healthy subjects. 191
Imidazo[2,1-b]thiazole System: a Scaffold Endowing Dihydropyridines With Selective Cardiodepressant Activity 190
Agonist-Regulated Internalization and desensitization of the Human Nociceptin Receptor Expressed in CHO Cells 188
β-Endorphin in pressor response to hyperventilation in elderly patients with essential and secondary hypertension 187
Synthesis and evaluation of the affinity toward mu-opioid receptor of atypical, lipophilic ligands based on the sequence c[Tyr-Pro-Trp-Phe-Gly-]. 186
Expression of the repressor element-1 silencing transcription factor (REST) is influenced by insulin-like growth factor-I in differentiating human neuroblastoma cells. 185
Synthesis and assay of retro-α4β1 integrin-targeting motifs 185
Investigation of the Interaction Between the Atypical Agonist c[YpwFG] and MOR 184
Antisense versus proopiomelanocortin mRNA reduces vascular risk in a murine model of type-2 diabetes following stress exposure in early post-natal life. 182
Synthesis and pharmacological profile of a series of 1-substituted-2-carbonyl derivatives of diphenidol: novel M4 muscarinic receptor antagonists 181
Contribution of alpha4beta1 integrin to the antiallergic effect of levocabastine 181
DESIGN AND SYNTHESIS OF OPIOID PEPTIDE ANALOGUES AND MIMETICS 181
Modulation of αvβ3- and α5β1-integrin-mediated adhesion by dehydro-β-amino acids containing peptidomimetics 181
The Inverse Type II β-Turn on D-Trp-Phe, a Pharmacophoric Motif for MOR Agonists. 179
Attività calcio modulatrice a livello cardiaco e vasale di derivati imidazo[2,1-b]tiazolici 179
Plasma nociceptin/orphanin FQ levels rise after spontaneous episodes of angina, but not during induced myocardial ischemia 179
A Blocking Group Scan Using a Spherical Organometallic Complex Identifies an Unprecedented Binding Mode with Potent Activity In Vitro and In Vivo for the Opioid Peptide Dermorphin 178
Administration of antisense oligonucleotide against pro-opiomelanocortin prevents enduring hormonal alterations induced by neonatal handling in male mice. 177
Opioid Activity Profiles of Oversimplified Peptides Lacking in the Protonable N-Terminus 177
Eosinophil as a cellular target of the ocular anti-allergic action of mapracorat, a novel selective glucocorticoid receptor agonist 176
Design, Pharmacological Characterization, and Molecular Docking of Minimalist Peptidomimetic Antagonists of α4β1 Integrin 172
Phase II drugs under investigation for allergic conjunctivitis 172
mu-opioid receptor (MOR) expression and opioid-mediated intracellular signalling are altered in glial cells exposed to TNF-alpha 169
Early post-natal life stress induces permanent adrenocorticotropin-dependent hypercortisolism in male mice 169
Pain and child: a translational hypothesis on the pathophysiology of a mild type-2 diabetes model. 168
Postnatal Stress Procedures Induce Long-Term Endocrine and Metabolic Alterations Involving Different Proopiomelanocortin-Derived Peptides 168
Cyclotetrapeptide Mimics based on a 13-Membered, Partially Modified Retro-Inverso Structure 167
Sviluppo di un biosensore luminescente basato su una linea cellulare ricombinante di epatocarcinoma umano (HepG2) per la determinazione dell’attività di acidi biliarinaturali e sintetici 166
Agonist-regulated endocytosis and desensitization of the human nociceptin receptor 166
Brain-body metabolic programming and functional derangement in a type-2 diabetes model in male mice: the role exerted by opioid and HPA systems. 166
NEW PEPTIDOMIMETIC α4β1-INTEGRIN ANTAGONISTS FOR REDUCING INFLAMMATION AND ALLERGIC REACTIONS 166
Role of nociceptin/orphanin FQ in thermoregulation 166
Design and Pharmacological Characterization of α4β1 Integrin Cyclopeptide Agonists: Computational Investigation of Ligand Determinants for Agonism versus Antagonism 165
FXR activity modulation by bile acids and analogs assessed with a recombinant HepG2 cell-based luciferase assay. 164
A new generation of opioid peptidomimetics acting as central and/or peripheral analgesics 163
Prodynorphin-Derived Opioid Peptides 162
Prodynorphin-derived peptides 162
BNP in normotesi ed ipertesi con sospetta insufficienza coronarica sottoposti a scintigrafia miocardica con adenosina 162
Development of new beta-lactam-based integrin ligands: Synthesis and Applications 162
New coumarin-based anti-inflammatory drug: putative antagonist of the integrins alpha(L)beta(2) and alpha(M)beta(2). 161
Inhibition of cancer cell adhesion by heterochiral Pro-containing RGD mimetics. 161
Plasma Brain Natriuretic Peptide at rest and after adenosine-induced myocardial ischemia in normotensive and essential hypertensive patients with suspected coronary artery disease 161
Selective detection of α4β1 integrin (VLA-4)-expressing cells using peptide-functionalized nanostructured materials mimicking endothelial surfaces adjacent to inflammatory sites 161
Synthesis and Conformational Analysis of Cyclotetrapeptide Mimetic beta-Turn Templates and Validation as 3D Scaffolds 158
Analysis of the muscarinic receptor subtype mediating inhibition of the neurogenic contractions in rabbit isolated vas deferens by a series of polymethylene tetra-amines 157
Development of isoxazoline-containing peptidomimetics as dual alpha-v-beta-3 and alpha-5-beta-1 integrin ligands. 156
Versatile Picklocks to Access All Opioid Receptors: Tuning the Selectivity and Functional Profile of the Cyclotetrapeptide c[Phe- d -Pro-Phe-Trp] (CJ-15,208) 156
Etiopathogenesis and pharmacological prevention of a type-2 diabetes model in male mice 155
DETERMINATION OF THE BIOLOGICALLY ACTIVE STRUCTURE OF THE ATYPICAL MOR-LIGAND c[D-Asp-1-amide-beta-Ala-D-Trp-Phe] AND ANALOGUES BY NMR AND MOLECULAR DOCKING 151
Design and synthesis of Alpha-v-beta-3 and Alpha-5-beta-1 integrin ligands as delivery systems for fluorescent molecules 151
TARGETING INTEGRINS WITH NEW BETA-LACTAM DERIVATIVES 150
Synthesis of Enantiomerically Pure alpha-v-beta-3 Integrin ligands Based on a 5,6-Dihydropyridin-2-one Scaffold. 150
Regulation of ileal bile acid-binding protein expression in Caco-2 cells by ursodeoxycholic acid 150
Transcriptional activation of human mu-opioid receptor gene by insulin-like growth factor-I in neuronal cells is modulated by the transcription factor REST 150
Long-term intrathecal morphine and bupivacaine upregulate MOR gene expression in lymphocytes. 149
Dehydro-beta-amino acids as scaffolds for the preparation of alpha-v-beta-3, alpha-5-beta-1 and alpha-4-beta-1 integrin ligands 149
Protective and worsening peripheral nociceptin/orphanin FQ receptor-mediated effect in a rat model of experimental colitis 149
Post-natal stress-induced endocrine and metabolic alterations in mice at adulthood involve different pro-opiomelanocortin-derived peptides 147
Protein aggregates and autophagy involvement in a family with a mutation in Z-band alternatively spliced PDZ-motif protein 146
Nandrolone decreases mu opioid receptor expression in SH-SY5Y human neuroblastoma cells 143
Mapracorat, a novel non-steroidal selective glucocorticoid receptor agonist for the treatment of allergic conjunctivitis 143
Overview of genetic analysis of human opioid receptors 142
Development and characterization of novel EphB1 receptor antagonists. 141
Side chain effect in the modulation of αvβ3/α5β1 integrin activity via clickable isoxazoline-RGD-mimetics: development of molecular delivery systems 139
Enhanced brain performance in mice following postnatal stress 138
Selective Integrin Ligands Promote Cell Internalization of the Antineoplastic Agent Fluorouracil 136
Innovative opioid peptides and biased agonism: Novel avenues for more effective and safer analgesics to treat chronic pain 135
Novel Antagonist targeting EphB1 receptor 134
Septal grafts restore cognitive abilities and amyloid precursor protein metabolism. 133
Interactions between atypical opioid agonists and MOR 133
Peptidomimetic Scaffolds for the Discovery of New Bioactive Compounds. Cyclotetrapeptide Analogues Based on a 13-Membered, Partially Modified Retro-Inverso Structure. Applications to the synthesis of Cancer Cell Adhesion Inhibitors 132
Totale 18.126
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Categoria #
all - tutte 75.244
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 75.244
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021425 0 0 0 0 0 0 0 0 0 0 0 425
2021/20222.987 351 156 160 133 277 200 99 278 117 175 479 562
2022/20233.682 330 543 175 439 295 300 197 190 744 69 245 155
2023/20241.159 64 179 69 109 80 266 63 103 47 58 63 58
2024/20254.143 181 583 405 277 948 223 300 96 28 193 105 804
2025/20268.603 574 740 724 634 1.040 482 971 402 1.782 671 348 235
Totale 27.185