CRIS Current Research Information System

GOBBI, SILVIA
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
NA - Nord America 5.599
AS - Asia 4.174
EU - Europa 3.666
AF - Africa 279
SA - Sud America 214
OC - Oceania 10
Continente sconosciuto - Info sul continente non disponibili 4
Totale 13.946
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 5.530
CN - Cina 1.292
SG - Singapore 1.254
IT - Italia 825
GB - Regno Unito 798
VN - Vietnam 694
DE - Germania 524
SE - Svezia 317
HK - Hong Kong 300
UA - Ucraina 240
IN - India 224
RU - Federazione Russa 202
FR - Francia 152
BR - Brasile 150
NL - Olanda 131
IE - Irlanda 119
KR - Corea 101
CI - Costa d'Avorio 98
JO - Giordania 92
ZA - Sudafrica 75
JP - Giappone 66
BG - Bulgaria 57
FI - Finlandia 56
TG - Togo 56
EE - Estonia 52
CA - Canada 46
CH - Svizzera 33
ID - Indonesia 33
AR - Argentina 29
IR - Iran 29
PL - Polonia 29
SC - Seychelles 28
AT - Austria 25
BE - Belgio 17
ES - Italia 17
GR - Grecia 16
CZ - Repubblica Ceca 15
PK - Pakistan 15
MX - Messico 14
TR - Turchia 12
BD - Bangladesh 11
EC - Ecuador 11
HR - Croazia 11
NG - Nigeria 8
AU - Australia 7
LB - Libano 7
MY - Malesia 7
CL - Cile 6
CO - Colombia 6
LT - Lituania 6
PT - Portogallo 6
EG - Egitto 5
IQ - Iraq 5
HU - Ungheria 4
KZ - Kazakistan 4
PE - Perù 4
PH - Filippine 4
TH - Thailandia 4
A2 - ???statistics.table.value.countryCode.A2??? 3
AE - Emirati Arabi Uniti 3
BY - Bielorussia 3
DZ - Algeria 3
GT - Guatemala 3
NZ - Nuova Zelanda 3
PS - Palestinian Territory 3
PY - Paraguay 3
RO - Romania 3
SA - Arabia Saudita 3
UZ - Uzbekistan 3
AL - Albania 2
KW - Kuwait 2
MD - Moldavia 2
NO - Norvegia 2
PA - Panama 2
TN - Tunisia 2
UY - Uruguay 2
VE - Venezuela 2
AO - Angola 1
AZ - Azerbaigian 1
BB - Barbados 1
BO - Bolivia 1
CR - Costa Rica 1
CW - ???statistics.table.value.countryCode.CW??? 1
DO - Repubblica Dominicana 1
GH - Ghana 1
GI - Gibilterra 1
HN - Honduras 1
KE - Kenya 1
KG - Kirghizistan 1
LA - Repubblica Popolare Democratica del Laos 1
LK - Sri Lanka 1
MM - Myanmar 1
OM - Oman 1
RS - Serbia 1
SD - Sudan 1
Totale 13.946
Salva come PNG Salva come JPEG
Città #
Singapore 783
Southend 694
Ashburn 586
Fairfield 547
Chandler 521
Santa Clara 330
Woodbridge 313
Hong Kong 299
Bologna 286
Houston 262
Hefei 259
Seattle 249
Wilmington 241
Dong Ket 239
Cambridge 207
Princeton 172
Beijing 165
Ann Arbor 158
Jacksonville 158
Boardman 126
Dublin 118
Ho Chi Minh City 109
Abidjan 98
Seoul 98
New York 96
Amman 92
Hanoi 85
Dallas 75
Westminster 73
Los Angeles 71
Nanjing 69
Padova 64
Tokyo 63
Sofia 57
Lomé 56
Buffalo 55
Berlin 54
Munich 54
Bremen 47
San Diego 42
Jinan 40
Milan 39
Saint Petersburg 38
Shenyang 37
Helsinki 34
Redondo Beach 34
Redmond 32
Bern 29
Mülheim 28
Hebei 27
Jakarta 27
Tianjin 26
Bengaluru 25
Nanchang 25
Guangzhou 24
Frankfurt am Main 21
Council Bluffs 20
Nuremberg 20
Changsha 18
Shanghai 18
Brussels 17
Des Moines 17
Jiaxing 17
Mahé 17
Warsaw 17
Haiphong 16
Venezia 16
Medford 15
Olalla 15
Phoenix 15
Redwood City 15
São Paulo 15
Vienna 15
Boydton 14
Chicago 14
Dearborn 14
Mountain View 14
Zhengzhou 14
Falkenstein 13
Kunming 13
Verona 13
Brooklyn 12
London 12
Quận Bình Thạnh 12
Toronto 12
Turku 12
Hangzhou 11
Montreal 11
Taiyuan 11
Turin 11
Da Nang 10
Düsseldorf 10
Lappeenranta 10
San Giorgio di Piano 10
Falls Church 9
Fremont 9
Johannesburg 9
Ningbo 9
Norwalk 9
San Francisco 9
Totale 9.147
Salva come PNG Salva come JPEG
Nome #
1,4-dihydropyridine derivatives as calcium channel modulators: the role of 3-methoxy-flavone moiety 322
Discovery of novel benzofuran-based compounds with neuroprotective and immunomodulatory properties for Alzheimer's disease treatment 286
Benzofuran-Based Hybrid Compounds for the Inhibition of Cholinesterase Activity, Abeta Amyloid Aggregation, and Abeta Neurotoxicity 263
Cholinesterase inhibitors: xanthostigmine derivatives blocking the acetylcholinesterase-induced beta-amyloid aggregation. 235
Multitarget Strategy to Address Alzheimer's Disease: Design, Synthesis, Biological Evaluation, and Computational Studies of Coumarin-Based Derivatives 231
Progettazione e sintesi di derivati benzofuranici per la malattia di Alzheimer 216
Characterization and Heterologous Expression of the Oxalyl Coenzyme A Decarboxylase Gene from Bifidobacterium lactis 208
Analogues of the dual acetylcholinesterase inhibitor AP2238: synthesis and SAR 194
Design, synthesis and biological profile of new inhibitors of multidrug resistance associated proteins carrying a polycyclic scaffold 190
2-Arylbenzofuran-based molecules as multipotent Alzheimer's disease modifying agents 188
Benzophenones as xanthone-open model CYP11B1 inhibitors potentially useful for promoting wound healing 187
Versatility of the Curcumin Scaffold: Discovery of Potent and Balanced Dual BACE-1 and GSK-3β Inhibitors 183
Exploiting the chalcone scaffold to develop multifunctional agents for Alzheimer’s disease 181
Fatty Acid Amide Hydrolase (FAAH), Acetylcholinesterase (AChE), and Butyrylcholinesterase (BuChE): Networked Targets for the Development of Carbamates as Potential Anti-Alzheimer's Disease Agents 181
Chalcones induce apoptosis, autophagy and reduce spreading in osteosarcoma 3D models 179
Extensive SAR and computational studies of 3-{4-[(benzylmethylamino)methyl]phenyl}-6,7-dimethoxy-2H-2-chromenone (AP2238) derivatives. 179
Targeting neuronal calcium channels and GSK3β for Alzheimer's disease with naturally-inspired Diels-Alder adducts 176
Cardiovascular profile of xanthone-based 1,4 dihydropyridines bearing a lidoflazine pharmacophore fragment 175
Identification of chalcone-based antileishmanial agents targeting trypanothione reductase 169
Targeting the multifaceted neurotoxicity of Alzheimer's disease by tailored functionalisation of the curcumin scaffold 168
Identification of a new tamoxifen-xanthene hybrid as pro-apoptotic anticancer agent 167
Enantioselective nonsteroidal aromatase inhibitors identified through a multidisciplinary medicinal chemistry approach 162
Interplay Between Endocannabinoid System and Neurodegeneration: Focus on Polypharmacology 161
Anthracene Based Compounds as New L-type Ca2+ Channel Blockers: Design, Synthesis, and Full Biological Profile 161
CHOLINESTERASE INHIBITORS: SAR AND ENZYME INHIBITORY ACTIVITY OF 3-[omega-(BENZYLMETHYLAMINO)ALKOXY]XANTHEN-9-ONES 161
Natural-like Chalcones with Antitumor Activity on Human MG63 Osteosarcoma Cells 159
Emerging targets in neurodegeneration: new opportunities for Alzheimer's disease treatment? 157
Naturally inspired molecules as multifunctional agents for Alzheimer's disease treatment 156
Novel Curcumin-Diethyl Fumarate Hybrid as a Dualistic GSK-3β Inhibitor/Nrf2 Inducer for the Treatment of Parkinson's Disease 156
A Computational Assay of Estrogen Receptor α Antagonists Reveals the Key Common Structural Traits of Drugs Effectively Fighting Refractory Breast Cancers 155
Curcumin-1,2,3-triazole conjugation for targeting the cancer apoptosis machinery. 153
Balanced dual acting compounds targeting aromatase and estrogen receptor α as an emerging therapeutic opportunity to counteract estrogen responsive breast cancer 152
Clobenpropit analogs as dual activity ligands for the histamine H3 and H4 receptors: synthesis, pharmacological evaluation, and cross-target QSAR studies. 151
Lead optimization providing a series of flavone derivatives as potent nonsteroidal inhibitors of the cytochrome P450 aromatase enzyme 148
Polycyclic maleimide-based derivatives as first dual modulators of neuronal calcium channels and GSK-3β for Alzheimer's disease treatment 148
Fluorinated benzophenone derivatives: balanced multipotent agents for Alzheimer's disease 146
Derivati a struttura benzofenonica come inibitori dell'acetilcolinesterasi 145
Targeting Alzheimer’s disease: Novel indanone hybrids bearing a pharmacophoric fragment of AP2238 144
Nonsteroidal Aromatase inhibitors: synthesis and evaluation of new flavone derivatives 143
Homopterocarpanes as bridged triarylethylene analogues: synthesis and antagonistic effects in human MCF-7 breast cancer cells 143
Single-digit nanomolar inhibitors lock the aromatase active site via a dualsteric targeting strategy 142
Design, synthesis, and evaluation of benzophenone derivatives as novel acetylcholinesterase inhibitors 142
Multifaceted activity of polyciclic MDR revertant agents in drug-resistant leukemic cells: Role of the spacer 140
Imidazolylmethylbenzophenones as highly potent aromatase inhibitors. 139
PREPARATION AND STEREOCHEMICAL CHARACTERIZATION OF ENANTIOMERIC HOMOISOFLAVONES ACTIVE AS AROMATASE INHIBITORS 138
New derivatives of xanthenone-4-acetic acid: synthesis, pharmacological profile and effect on TNF-alpha and NO production by human immune cells 138
Antitumor profile of new phenothiazine derivatives 138
New Coumarin derivatives as cholinergic and cannabinoid system modulators 137
In vitro studies of flavon-8-acetic acid analogues 136
Benzophenone derivatives as Inhibitors of Acetylcholinesterase 135
In vitro biological activity of new analogues of flavon-8-acetic acid 134
Improved eradication efficacy of a combination of newly identified antimicrobial agents in C. albicans and S. aureus mixed-species biofilm 133
New potent P-glycoprotein inhibitors carrying a polycyclic scaffold 131
Studies on cytostatic and cytotoxic activity of new flavopiridol analogues 130
Multi-target strategy to address Alzheimer’s disease: Design, synthesis and biological evaluation of new tacrine-based dimers 130
Hybrid drugs for Alzheimer's disease: new indanone derivatives bearing a pharmacophoric fragment of AP2238 129
Novel Aldosterone Synthase Inhibitors with Extended Carbocyclic Skeleton by a Combined Ligand-Based and Structure-Based Drug Design Approach 126
Design, Synthesis, and Biological and Crystallographic Evaluation of Novel Inhibitors ofPlasmodium falciparumEnoyl-ACP-reductase (PfFabI) 125
Functionalization of the chalcone scaffold for the discovery of novel lead compounds targeting fungal infections 125
Reconsidering Aromatase for Breast Cancer Treatment: New Roles for an Old Target 125
Naturally Inspired Coumarin Derivatives in Alzheimer’s Disease Drug Discovery: Latest Advances and Current Challenges 124
null 123
Design of Multifunctional Compounds for Cardiovascular Disease: From Natural Scaffolds to “Classical” Multitarget Approach 121
Switching from Aromatase Inhibitors to Dual Targeting Flavonoid-Based Compounds for Breast Cancer Treatment 120
Targeting the Bacterial Membrane with a New Polycyclic Privileged Structure: A Powerful Tool To Face Staphylococcus aureus Infections 120
Hybrid-Based Multi-Target Ligands for the Treatment of Alzheimer's Disease 119
Novel highly potent and selective nonsteroidal aromatase inhibitors: synthesis, biological evaluation and structure-activity relationships investigation 119
null 118
Polycyclic Maleimide-based Scaffold as New Privileged Structure for Navigating the Cannabinoid System Opportunities 117
Targeting Orthosteric and Allosteric Pockets of Aromatase via Dual-Mode Novel Azole Inhibitors 117
From AChE to BACE1 inhibitors: The role of the amine on the indanone scaffold 116
Multidrug resistance reverting activity and antitumor profile of new phenothiazine derivatives 116
Flavonoid-inspired vascular disrupting agents: Exploring flavone-8-acetic acid and derivatives in the new century 116
The first dual ChE/FAAH inhibitors: new perspectives for Alzheimer's disease? 113
The ability of coumarin-, flavanon- and flavonol-analogues of flavone acetic acid to stimulate human monocytes. 112
Modulation of Cytochromes P450 with Xanthone-Based Molecules: From Aromatase to Aldosterone Synthase and Steroid 11β-Hydroxylase Inhibition 111
Nonsteroidal aromatase inhibitors for the treatment of breast cancer: an update. 108
New potent inhibitors of cytochrome P450 aromatase 107
Imidazolylmethylxanthones as potent inhibitors of cytochrome P450 aromatase 107
Mono- or di-fluorinated analogues of Flavone-8-acetic acid: synthesis and in vitro biological activity 106
null 105
Immune-modulating and anti-vascular activities of two xanthenone acetic acid analogues: a comparative study to DMXAA. 101
From nonsteroidal aromatase inhibitors to multifunctional drug candidates: classic and innovative strategies for the treatment of breast cancer. 100
Small-molecule inhibitors/modulators of amyloid-β peptide aggregation and toxicity for the treatment of Alzheimer's disease: a patent review (2010 – 2012) 98
Chalcone-based carbamates for Alzheimer's disease treatment 96
Coumarin derivatives as potential antitumor agents: Growth inhibition, apoptosis induction and multidrug resistance reverting activity 93
Tackling Alzheimer's Disease with Existing Drugs:A Promising Strategy for Bypassing Obstacles 90
Hitting drug-resistant malaria infection with triazole-linked flavonoid–chloroquine hybrid compounds 87
Chromone-based small molecules for multistep shutdown of arachidonate pathway: Simultaneous inhibition of COX-2, 15-LOX and mPGES-1 enzymes 85
null 82
null 79
null 76
null 70
null 67
Recent progress on curcumin-based therapeutics: a patent review (2012-2016). Part I: Curcumin 66
3-(4-{[benzyl(methyl)amino]methyl}-phenyl)-6,7-dimethoxy-2H-2-chromenone (AP2238) inhibits both acetylcholinesterase and acetylcholinesterase-induced β-amyloid aggregation: A dual function lead for Alzheimer's disease therapy 61
Acetylcholinesterase inhibitors: SAR and kinetic studies on ω-[N-methyl-N-(3-alkylcarbamoyloxyphenyl]methyl] aminoalkoxyaryl derivatives 58
null 58
Recent progress on curcumin-based therapeutics: a patent review (2012-2016). Part II: curcumin derivatives in cancer and neurodegeneration 58
Cardiovascular hybrid drugs: New benzazepinone derivatives as bradycardic agents endowed with selective β1-Non-competitive antagonism 55
Totale 13.747
Salva come PNG Salva come JPEG
Categoria #
all - tutte 40.615
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 40.615
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021936 0 0 0 0 0 77 27 128 103 76 94 431
2021/20221.612 144 39 108 86 134 82 48 159 90 125 303 294
2022/20232.157 197 247 92 262 168 169 53 129 448 59 156 177
2023/2024663 34 78 33 86 48 191 40 32 14 34 34 39
2024/20252.446 83 341 263 133 500 122 199 68 55 172 148 362
2025/20262.884 542 548 577 445 635 137 0 0 0 0 0 0
Totale 14.283