GOBBI, SILVIA
GOBBI, SILVIA
DIPARTIMENTO DI FARMACIA E BIOTECNOLOGIE
Docenti di ruolo di IIa fascia
Chromone-based small molecules for multistep shutdown of arachidonate pathway: Simultaneous inhibition of COX-2, 15-LOX and mPGES-1 enzymes
2024 Elzahhar P.A.; Orioli R.; Hassan N.W.; Gobbi S.; Belluti F.; Labib H.F.; El-Yazbi A.F.; Nassra R.; Belal A.S.F.; Bisi A.
Switching from Aromatase Inhibitors to Dual Targeting Flavonoid-Based Compounds for Breast Cancer Treatment
2023 Gobbi S.; Martini S.; Rozza R.; Spinello A.; Caciolla J.; Rampa A.; Belluti F.; Zaffaroni N.; Magistrato A.; Bisi A.
Targeting the multifaceted neurotoxicity of Alzheimer's disease by tailored functionalisation of the curcumin scaffold
2023 De Lorenzi, Ersilia; Seghetti, Francesca; Tarozzi, Andrea; Pruccoli, Letizia; Contardi, Cecilia; Serra, Massimo; Bisi, Alessandra; Gobbi, Silvia; Vistoli, Giulio; Gervasoni, Silvia; Argentini, Carla; Ghirardo, Giulia; Guarato, Giulia; Orso, Genny; Belluti, Federica; Di Martino, Rita Maria Concetta; Zusso, Morena
Hitting drug-resistant malaria infection with triazole-linked flavonoid–chloroquine hybrid compounds
2022 Seghetti, Francesca; Belluti, Federica; Rampa, Angela; Gobbi, Silvia; Legac, Jenny; Parapini, Silvia; Basilico, Nicoletta; Bisi, Alessandra
Interplay Between Endocannabinoid System and Neurodegeneration: Focus on Polypharmacology
2022 Seghetti F.; Gobbi S.; Belluti F.; Rampa A.; Bisi A.
Natural-like Chalcones with Antitumor Activity on Human MG63 Osteosarcoma Cells
2022 Rossi, Martina; Cappadone, Concettina; Picone, Giovanna; Bisi, Alessandra; Farruggia, Giovanna; Belluti, Federica; Blasi, Paolo; Gobbi, Silvia; Malucelli, Emil
Single-digit nanomolar inhibitors lock the aromatase active site via a dualsteric targeting strategy
2022 Caciolla J.; Martini S.; Spinello A.; Belluti F.; Bisi A.; Zaffaroni N.; Magistrato A.; Gobbi S.
Targeting neuronal calcium channels and GSK3β for Alzheimer's disease with naturally-inspired Diels-Alder adducts
2022 Bisi A.; Feoli A.; Trezza A.; Viejo L.; Formaggio F.; Bartolini M.; Belluti F.; Gobbi S.; Spiga O.; Caprini M.; de los Rios C.; Castellano S.; Rampa A.
Balanced dual acting compounds targeting aromatase and estrogen receptor α as an emerging therapeutic opportunity to counteract estrogen responsive breast cancer
2021 Caciolla J.; Martini S.; Spinello A.; Pavlin M.; Turrini E.; Simonelli F.; Belluti F.; Rampa A.; Bisi A.; Fimognari C.; Zaffaroni N.; Gobbi S.; Magistrato A.
Flavonoid-inspired vascular disrupting agents: Exploring flavone-8-acetic acid and derivatives in the new century
2021 Gobbi S.; Belluti F.; Rampa A.; Bisi A.
Improved eradication efficacy of a combination of newly identified antimicrobial agents in C. albicans and S. aureus mixed-species biofilm
2021 Bonvicini F.; Belluti F.; Bisi A.; Gobbi S.; Manet I.; Gentilomi G.A.
Multifaceted activity of polyciclic MDR revertant agents in drug-resistant leukemic cells: Role of the spacer
2021 Caciolla J.; Picone G.; Farruggia G.; Valenti D.; Rampa A.; Malucelli E.; Belluti F.; Trezza A.; Spiga O.; Iotti S.; Gobbi S.; Cappadone C.; Bisi A.
New Coumarin derivatives as cholinergic and cannabinoid system modulators
2021 Montanari S.; Allara M.; Scalvini L.; Kostrzewa M.; Belluti F.; Gobbi S.; Naldi M.; Rivara S.; Bartolini M.; Ligresti A.; Bisi A.; Rampa A.
Tackling Alzheimer's Disease with Existing Drugs:A Promising Strategy for Bypassing Obstacles
2021 Rampa, Angela; Gobbi, Silvia; Belluti, Federica; Bisi, Alessandra
Curcumin-1,2,3-triazole conjugation for targeting the cancer apoptosis machinery.
2020 Seghetti F., Di Martino R.M.C., Catanzaro E., Bisi A., Gobbi S., Rampa A., Canonico B., Montanari M., Krysko D.V., Papa S., Fimognari C., Belluti F.
Novel Curcumin-Diethyl Fumarate Hybrid as a Dualistic GSK-3β Inhibitor/Nrf2 Inducer for the Treatment of Parkinson's Disease
2020 Rita Maria Concetta Di Martino; Letizia Pruccoli; Alessandra Bisi; Silvia Gobbi; Angela Rampa; Ana Martinez; Concepción Pérez; Loreto Martinez-Gonzalez; Maria Paglione; Elia Di Schiavi; Francesca Seghetti; Andrea Tarozzi; Federica Belluti
Reconsidering Aromatase for Breast Cancer Treatment: New Roles for an Old Target
2020 Caciolla J.; Bisi A.; Belluti F.; Rampa A.; Gobbi S.
Targeting Orthosteric and Allosteric Pockets of Aromatase via Dual-Mode Novel Azole Inhibitors
2020 Caciolla J.; Spinello A.; Martini S.; Bisi A.; Zaffaroni N.; Gobbi S.; Magistrato A.
Benzophenones as xanthone-open model CYP11B1 inhibitors potentially useful for promoting wound healing
2019 Gobbi S.; Hu Q.; Foschi G.; Catanzaro E.; Belluti F.; Rampa A.; Fimognari C.; Hartmann R.W.; Bisi A.
Discovery of novel benzofuran-based compounds with neuroprotective and immunomodulatory properties for Alzheimer's disease treatment
2019 Montanari S.; Mahmoud A.M.; Pruccoli L.; Rabbito A.; Naldi M.; Petralla S.; Moraleda I.; Bartolini M.; Monti B.; Iriepa I.; Belluti F.; Gobbi S.; Di Marzo V.; Bisi A.; Tarozzi A.; Ligresti A.; Rampa A.
| Titolo | Autore(i) | Anno | Periodico | Editore | Tipo | File |
|---|---|---|---|---|---|---|
| Chromone-based small molecules for multistep shutdown of arachidonate pathway: Simultaneous inhibition of COX-2, 15-LOX and mPGES-1 enzymes | Elzahhar P.A.; Orioli R.; Hassan N.W.; Gobbi S.; Belluti F.; Labib H.F.; El-Yazbi A.F.; Nassra R....; Belal A.S.F.; Bisi A. | 2024-01-01 | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
| Switching from Aromatase Inhibitors to Dual Targeting Flavonoid-Based Compounds for Breast Cancer Treatment | Gobbi S.; Martini S.; Rozza R.; Spinello A.; Caciolla J.; Rampa A.; Belluti F.; Zaffaroni N.; Mag...istrato A.; Bisi A. | 2023-01-01 | MOLECULES | - | 1.01 Articolo in rivista | 2023 Molecules.pdf; molecules-28-03047-s001.zip |
| Targeting the multifaceted neurotoxicity of Alzheimer's disease by tailored functionalisation of the curcumin scaffold | De Lorenzi, Ersilia; Seghetti, Francesca; Tarozzi, Andrea; Pruccoli, Letizia; Contardi, Cecilia; ...Serra, Massimo; Bisi, Alessandra; Gobbi, Silvia; Vistoli, Giulio; Gervasoni, Silvia; Argentini, Carla; Ghirardo, Giulia; Guarato, Giulia; Orso, Genny; Belluti, Federica; Di Martino, Rita Maria Concetta; Zusso, Morena | 2023-01-01 | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | Targeting the multifaceted neurotoxicity of Alzheimer's disease by tailored functionalisation of the curcumin scaffold.pdf |
| Hitting drug-resistant malaria infection with triazole-linked flavonoid–chloroquine hybrid compounds | Seghetti, Francesca; Belluti, Federica; Rampa, Angela; Gobbi, Silvia; Legac, Jenny; Parapini, Sil...via; Basilico, Nicoletta; Bisi, Alessandra | 2022-01-01 | FUTURE MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
| Interplay Between Endocannabinoid System and Neurodegeneration: Focus on Polypharmacology | Seghetti F.; Gobbi S.; Belluti F.; Rampa A.; Bisi A. | 2022-01-01 | CURRENT MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | Seghetti 2022 postprint IRIS.pdf |
| Natural-like Chalcones with Antitumor Activity on Human MG63 Osteosarcoma Cells | Rossi, Martina; Cappadone, Concettina; Picone, Giovanna; Bisi, Alessandra; Farruggia, Giovanna; B...elluti, Federica; Blasi, Paolo; Gobbi, Silvia; Malucelli, Emil | 2022-01-01 | MOLECULES | - | 1.01 Articolo in rivista | Molecules 27 (2022) 3751.pdf |
| Single-digit nanomolar inhibitors lock the aromatase active site via a dualsteric targeting strategy | Caciolla J.; Martini S.; Spinello A.; Belluti F.; Bisi A.; Zaffaroni N.; Magistrato A.; Gobbi S. | 2022-01-01 | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | Gobbi 2022 postprint_IRIS.pdf |
| Targeting neuronal calcium channels and GSK3β for Alzheimer's disease with naturally-inspired Diels-Alder adducts | Bisi A.; Feoli A.; Trezza A.; Viejo L.; Formaggio F.; Bartolini M.; Belluti F.; Gobbi S.; Spiga O....; Caprini M.; de los Rios C.; Castellano S.; Rampa A. | 2022-01-01 | BIOORGANIC CHEMISTRY | - | 1.01 Articolo in rivista | Bisi 2022 postprint IRIS.pdf |
| Balanced dual acting compounds targeting aromatase and estrogen receptor α as an emerging therapeutic opportunity to counteract estrogen responsive breast cancer | Caciolla J.; Martini S.; Spinello A.; Pavlin M.; Turrini E.; Simonelli F.; Belluti F.; Rampa A.; ...Bisi A.; Fimognari C.; Zaffaroni N.; Gobbi S.; Magistrato A. | 2021-01-01 | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
| Flavonoid-inspired vascular disrupting agents: Exploring flavone-8-acetic acid and derivatives in the new century | Gobbi S.; Belluti F.; Rampa A.; Bisi A. | 2021-01-01 | MOLECULES | - | 1.01 Articolo in rivista | 2021 Gobbi.pdf |
| Improved eradication efficacy of a combination of newly identified antimicrobial agents in C. albicans and S. aureus mixed-species biofilm | Bonvicini F.; Belluti F.; Bisi A.; Gobbi S.; Manet I.; Gentilomi G.A. | 2021-01-01 | RESEARCH IN MICROBIOLOGY | - | 1.01 Articolo in rivista | RESMIC_2021.pdf; 1-s2.0-S0923250821000875-mmc1.docx |
| Multifaceted activity of polyciclic MDR revertant agents in drug-resistant leukemic cells: Role of the spacer | Caciolla J.; Picone G.; Farruggia G.; Valenti D.; Rampa A.; Malucelli E.; Belluti F.; Trezza A.; ...Spiga O.; Iotti S.; Gobbi S.; Cappadone C.; Bisi A. | 2021-01-01 | BIOORGANIC CHEMISTRY | - | 1.01 Articolo in rivista | Bioorg Chem.pdf |
| New Coumarin derivatives as cholinergic and cannabinoid system modulators | Montanari S.; Allara M.; Scalvini L.; Kostrzewa M.; Belluti F.; Gobbi S.; Naldi M.; Rivara S.; Ba...rtolini M.; Ligresti A.; Bisi A.; Rampa A. | 2021-01-01 | MOLECULES | - | 1.01 Articolo in rivista | molecules-26-03254 (4).pdf |
| Tackling Alzheimer's Disease with Existing Drugs:A Promising Strategy for Bypassing Obstacles | Rampa, Angela; Gobbi, Silvia; Belluti, Federica; Bisi, Alessandra | 2021-01-01 | CURRENT MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | Bisi CMC.pdf |
| Curcumin-1,2,3-triazole conjugation for targeting the cancer apoptosis machinery. | Seghetti F., Di Martino R.M.C., Catanzaro E., Bisi A., Gobbi S., Rampa A., Canonico B., Montanari... M., Krysko D.V., Papa S., Fimognari C., Belluti F. | 2020-01-01 | MOLECULES | - | 1.01 Articolo in rivista | Molecules_2020_Curcumins.pdf |
| Novel Curcumin-Diethyl Fumarate Hybrid as a Dualistic GSK-3β Inhibitor/Nrf2 Inducer for the Treatment of Parkinson's Disease | Rita Maria Concetta Di Martino; Letizia Pruccoli; Alessandra Bisi; Silvia Gobbi; Angela Rampa; An...a Martinez; Concepción Pérez; Loreto Martinez-Gonzalez; Maria Paglione; Elia Di Schiavi; Francesca Seghetti; Andrea Tarozzi; Federica Belluti | 2020-01-01 | ACS CHEMICAL NEUROSCIENCE | - | 1.01 Articolo in rivista | cn0c00363.pdf; cn0c00363_si_001.pdf |
| Reconsidering Aromatase for Breast Cancer Treatment: New Roles for an Old Target | Caciolla J.; Bisi A.; Belluti F.; Rampa A.; Gobbi S. | 2020-01-01 | MOLECULES | - | 1.01 Articolo in rivista | Molecules review 2020.pdf |
| Targeting Orthosteric and Allosteric Pockets of Aromatase via Dual-Mode Novel Azole Inhibitors | Caciolla J.; Spinello A.; Martini S.; Bisi A.; Zaffaroni N.; Gobbi S.; Magistrato A. | 2020-01-01 | ACS MEDICINAL CHEMISTRY LETTERS | - | 1.01 Articolo in rivista | - |
| Benzophenones as xanthone-open model CYP11B1 inhibitors potentially useful for promoting wound healing | Gobbi S.; Hu Q.; Foschi G.; Catanzaro E.; Belluti F.; Rampa A.; Fimognari C.; Hartmann R.W.; Bisi A. | 2019-01-01 | BIOORGANIC CHEMISTRY | - | 1.01 Articolo in rivista | - |
| Discovery of novel benzofuran-based compounds with neuroprotective and immunomodulatory properties for Alzheimer's disease treatment | Montanari S.; Mahmoud A.M.; Pruccoli L.; Rabbito A.; Naldi M.; Petralla S.; Moraleda I.; Bartolin...i M.; Monti B.; Iriepa I.; Belluti F.; Gobbi S.; Di Marzo V.; Bisi A.; Tarozzi A.; Ligresti A.; Rampa A. | 2019-01-01 | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | benzo AM .pdf |