CRIS Current Research Information System

SPINELLI, DOMENICO
 Distribuzione geografica
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Continente #
NA - Nord America 5.020
EU - Europa 4.051
AS - Asia 3.667
AF - Africa 262
SA - Sud America 217
OC - Oceania 10
Continente sconosciuto - Info sul continente non disponibili 3
Totale 13.230
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Nazione #
US - Stati Uniti d'America 4.989
CN - Cina 1.199
SG - Singapore 1.130
GB - Regno Unito 1.084
IT - Italia 703
VN - Vietnam 572
DE - Germania 514
SE - Svezia 443
UA - Ucraina 383
HK - Hong Kong 255
RU - Federazione Russa 210
IN - India 207
FR - Francia 193
BR - Brasile 161
IE - Irlanda 132
NL - Olanda 98
ZA - Sudafrica 84
KR - Corea 83
JP - Giappone 80
EE - Estonia 68
JO - Giordania 66
CI - Costa d'Avorio 59
TG - Togo 50
SC - Seychelles 45
BG - Bulgaria 42
FI - Finlandia 39
BE - Belgio 34
CH - Svizzera 30
AR - Argentina 27
CA - Canada 18
GR - Grecia 16
HR - Croazia 16
BD - Bangladesh 14
ID - Indonesia 13
NG - Nigeria 12
CL - Cile 10
ES - Italia 10
PL - Polonia 10
TR - Turchia 10
EC - Ecuador 8
MX - Messico 8
LB - Libano 7
LT - Lituania 7
AU - Australia 6
CO - Colombia 5
IQ - Iraq 5
IR - Iran 4
TN - Tunisia 4
AM - Armenia 3
CR - Costa Rica 3
CZ - Repubblica Ceca 3
EG - Egitto 3
MA - Marocco 3
NZ - Nuova Zelanda 3
RO - Romania 3
A2 - ???statistics.table.value.countryCode.A2??? 2
AT - Austria 2
BY - Bielorussia 2
LK - Sri Lanka 2
MY - Malesia 2
PY - Paraguay 2
SI - Slovenia 2
TW - Taiwan 2
UZ - Uzbekistan 2
VE - Venezuela 2
AE - Emirati Arabi Uniti 1
AZ - Azerbaigian 1
BA - Bosnia-Erzegovina 1
CY - Cipro 1
DK - Danimarca 1
DO - Repubblica Dominicana 1
DZ - Algeria 1
GA - Gabon 1
HU - Ungheria 1
KG - Kirghizistan 1
LA - Repubblica Popolare Democratica del Laos 1
MD - Moldavia 1
MT - Malta 1
NI - Nicaragua 1
NO - Norvegia 1
OM - Oman 1
PE - Perù 1
PH - Filippine 1
PK - Pakistan 1
PT - Portogallo 1
PW - Palau 1
QA - Qatar 1
SA - Arabia Saudita 1
TL - Timor Orientale 1
UY - Uruguay 1
XK - ???statistics.table.value.countryCode.XK??? 1
Totale 13.230
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Città #
Southend 919
Singapore 731
Fairfield 468
Chandler 463
Ashburn 431
Santa Clara 344
Hefei 308
Jacksonville 278
Hong Kong 255
Wilmington 240
Woodbridge 233
Ann Arbor 221
Seattle 208
Princeton 194
Houston 191
Dong Ket 183
Cambridge 157
Beijing 155
Dublin 131
Boardman 122
Nanjing 99
Westminster 92
Turin 91
Padova 89
Ho Chi Minh City 81
Seoul 81
Bologna 80
Tokyo 80
Berlin 72
Hanoi 69
Amman 66
Los Angeles 66
Abidjan 59
Jinan 57
Buffalo 56
New York 56
The Dalles 55
Milan 53
Dallas 50
Lomé 50
Saint Petersburg 43
Medford 42
Sofia 42
Shenyang 41
San Diego 37
Brussels 34
Munich 34
Mülheim 34
Mahé 33
Rome 33
Changsha 32
Helsinki 31
Tianjin 25
Nanchang 24
Redmond 22
Bengaluru 21
Bern 21
Bremen 21
Hebei 21
Dearborn 18
Frankfurt am Main 18
London 18
Verona 18
Falkenstein 17
Guangzhou 17
Redwood City 17
Olalla 16
Redondo Beach 16
Shanghai 14
Zhengzhou 14
Da Nang 13
Jiaxing 13
Mountain View 13
Norwalk 13
Washington 13
Yubileyny 13
Abeokuta 12
São Paulo 12
Haikou 11
Hangzhou 11
Phoenix 11
Des Moines 10
Lanzhou 10
Orem 10
Bühl 9
Düsseldorf 8
Kunming 8
Moscow 8
Naples 8
Ningbo 8
Chicago 7
Ha Long 7
Haiphong 7
Hyderabad 7
Modena 7
Ninh Bình 7
Taizhou 7
Turku 7
Wuhan 7
Biên Hòa 6
Totale 8.691
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Nome #
Sintesi di tioeteri, solfossidi, solfoni e tioesteri dei 3-aroil-4(Z)-[1-metil-2-sulfanil-vinil]-4H-[1,2,4]ossadiazol-5-oni e loro attività come calcio antagonisti 306
A new class of selective myocardial calcium channel modulators 2. Role of the acetal chain in oxadiazol-3-one derivatives 247
C-C coupling between trinitrothiophenes and triaminobenzenes: Zwitterionic intermediates and new all-conjugated structures 203
New Model for a Theoretical Density Functional Theory Investigation of the Mechanism of the Carbonic Anhydrase: How Does the Internal Bicarbonate Rearrangement Occur? 196
On the reactivity of some 2-methyleneindolines with b-nitroenamines, a-nitroalkenes, and 1,2-diaza-1,3-butadienes 191
Convergent results from experimental and theoretical DFT studies of the intramolecular rearrangement of Z-hydrazones of 3-acetyl-1,2,4-oxadiazoles 187
Can the absence of solvation of neutral reagents by ionic liquids be responsible for the high reactivity in base-assisted intramolecular nucleophilic substitutions in these solvents? 182
Absolute configuration and biological profile of two thiazinooxadiazol-3-ones with L-type calcium channel activity: a study of the structural effects 179
On the Dichotomic Behavior of the Z-2,4-Dinitrophenylhydrazone of 5-Amino-3-benzoyl-1,2,4-oxadiazole with Acids in Toluene and in Dioxane/Water: Rearrangement versus Hydrolisis 178
Analysis of the recent antipsychotic aripiprazole in human plasma by capillary electrophoresis and high performance liquid chromatography with diode array detection 178
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3-Aryl-4-nitrobenzothiochromans S,S-dioxide: From Calcium-Channel Modulators Properties to Multidrug-Resistance Reverting Activity 166
Catalytic Mechanism of Diaminopimelate Epimerase: A QM/MM Investigation 164
Modellistica molecolare applicata a modulatori dei canali del calcio 157
Utilizzo dei Campi di Interazione Molecolare nella Ricerca di Molecole Biologicamente Attive 157
Calcium Antagonists Discovered by a Multidisciplinary Approach. 156
Substituent effect on the electrochemical behaviour of some ortho-substituted (aryl)(2-nitrobenzo[b]thiophen-3-yl)amines. A combined experimental and computational study 156
Easy access to 4-nitrothiochroman S.S-dioxides via ring-enlargement from 3-nitrobenzo[b]thiophene 156
The First Example of an Irreversible Ring-Degenerate Rearrangement on Five-Membered Heterocycles by Attack of an External Bidentate Nucleophile 155
SINTESI DI COMPOSTI ETEROCICLICI MEDIANTE ESPANSIONE D’ANELLO DI NITROTIOFENI: 3-ARIL-2-FENIL-4-NITROTIOCROMANI S,S-DIOSSIDI DAL 3-NITROBENZO[b]TIOFENE 154
L-Type Calcium Channel Blockers: From Diltiazem to 1,2,4-Oxadiazol-5-ones via Thiazinooxadiazol-3-one Derivatives 153
A multidisciplinary study of chemico-physical properties of different classes of 2-aryl-5(or 6)-nitrobenzimidazoles: NMR, electrochemical behavior, ESR, and DFT calculations 153
New calcium channel modilators discovered by virtual screening 152
Computational QM/MM Study of the Reaction Mechanism of Human Glutathione S-Transferase A3-3 150
The Catalytic Activity of Diaminopimelate Epimerase: a QM/MM Study 148
The Catalytic Activity of Proline Racemase: a QM/MM Study 146
TRASPOSIZIONI ETEROCICLICHE MONONUCLEARI. APPLICAZIONE DELL’EQUAZIONE DI FUJITA-NISHIOKA ALLA REATTIVITA’ DI Z FENILIDRAZONI DI- E POLI-SOSTITUITI DEL 3-BENZOIL-5-FENIL-1,2,4-OSSADIAZOLO 145
Bis (2,2,2-trifluoroethyl) Chlorophosphate 145
REATTIVITA’ DEGLI Z-IDRAZONI, -SEMICARBAZONI E -FENILSEMICARBAZONI DEL 3 BENZOIL-5-FENIL-1,2,4-OSSADIAZOLO: EFFETTO DELLA STRUTTURA DELLA CATENA LATERALE 141
Five-to-Six Membered Ring-rearrangements in the Reaction of 5-Perfluoroalkyl-1,2,4-oxadiazoles with Hydrazine and Methylhydrazine 141
An Unexpected Pathway to Enantiomerization of Hemithioketals in Toluene Involving a Dimeric Transition State: A Combined Experimental and Computational Study 140
STUDIO CINETICO DELLA TRASPOSIZIONE DI Z-FENILIDRAZONI POLISOSTITUITI DEL 3-BENZOIL-5-FENIL-1,2,4-OSSADIAZOLI NEI CORRISPONDENTI 2-ARIL-5-FENIL-1,2,3-TRIAZOLI IN H2O/DIOSSANO 139
Stereoselective Behavior of the Functional Diltiazem Analogue 1-[(4-Chlorophenyl)sulfonyl]-2-(2-thienyl)pyrrolidine, a New L-Type Calcium Channel Blocker 139
Spectroscopic and electrochemical properties of 1- or 2-alkyl substituted 5- and 6-nitroindazoles 139
Fluorinated heterocyclic compounds. An effective strategy for the synthesis of fluorinated Z-oximes of 3-perfluoroalkyl-6-phenyl-2H-1,2,4-triazin- 5-ones via a ring-enlargement reaction of 3-benzoyl-5-perfluoroalkyl-1,2,4-oxadiazoles and hydrazine. 138
Trinitrothiophenes/Tris(alkylamino)benzenes reactions: new insights on nucleophilic/electrophilic interaction 138
SINTESI DI COMPOSTI ETEROCICLICI MEDIANTE ESPANSIONE D’ANELLO DI NITROTIOFENI: 3-ARIL-4-NITROTIOCROMANI E 3-ARIL-4-TIOCROMANONI S,S-DIOSSIDI DAL 3-NITROBENZO[b]TIOFENE 137
NMR study of the (Z)-phenylhydrazones of 5-alkyl- and 5-aryl-3-benzoyl-1,2,4-oxadiazoles: Support for the interpretation of kinetic results on the rearrangement of 1,2,4-oxadiazoles to 1,2,3-triazoles. 137
EFFETTI DELLA LUNGHEZZA DELLA CATENA ALCHILICA SULLA VELOCITA’ DI TRASPOSIZIONE DI ALCUNI Z-FENILIDRAZONI DI 5-ALCHILI-3-BENZOIL-1,2,4-OSSADIAZOLI 137
Un approccio multidisciplinare per lo studio di modulatori di canali del Ca2+ di tipo-L 136
Discovery of novel and cardioselective diltiazem-like calcium channel blockers via virtual screening. 136
Mononuclear Rearrangement of the Z-Phenylhydrazones of Some 3-Acyl-1,2,4-oxadiazoles: Effect of Substituents on the Nucleophilic Character of the >c=N-NH-C 6 H 5 Chain and on the Charge Density of N-2 of the 1,2,4-Oxadiazole Ring (Electrophilic Counterpart) 136
NUOVE TRASFORMAZIONI DI BUILDING-BLOCKS DINITROBUTADIENICI DERIVANTI DALL’APERTURA D’ANELLO DEL 3,4-DINITROTIOFENE 135
Inhibition of cell proliferation, cytotoxicity and induction of apoptosis of 1,4-bis(1-naphthyl)-2,3-dinitro-1,3-butadiene in gastrointestinal tumour cell lines and preliminary evaluation of its toxicity in vivo. 134
The Catalytic Activity of Proline Racemase: a QM/MM Study 134
TRASPOSIZIONI MONONUCLEARI DI ETEROCICLI. REATTIVITA’ DI Z-ARILIDRAZONI DEL 5-AMMINO-3-BENZOIL-1,2,4-OSSADIAZOLO IN D/W: EFFETTO DEI SOSTITUENTI 133
STEREOSELETTIVITÀ DI UNA BENZENSOLFONAMMIDE (M8), COME MODULATORE DEI CANALI DEL CALCIO DI TIPO-L 133
Electron Ionization Induced Fragmentation of some 3-Aroylamino-5-Methyl-1,2,4- Oxadiazoles and 3-Acetylamino-5-Aryl-1,2,4-Oxadiazoles 133
Nitroalkylation and nitroalkenylation reactions of g-lactone enolates. A facile ring switch from polysubstituted g-lactones to polysubstituted g-lactams 132
New classes of calcium channel modulators: thiazinooxadiazol-3-one and oxadiazol-5-one derivatives 131
REATTIVITA’ DI Z-ARILIDRAZONI DEL 5-AMMINO-3-BENZOIL-1,2,4-OSSADIAZOLO IN PRESENZA DI ACIDO TRICLOROACETICO E DI PIPERIDINA IN TOLUENE: CONFRONTO CON I DATI IN DIOSSANO-ACQUA 131
ANTICANCER ACTIVITY OF 1,4-BIS(1-NAPHTHYL)-2,3-DINITRO-1,3-BUTADIENE:CURRENT STATE OF THE RESEARCH 131
Inhibition of MDR1 activity and induction of apoptosis by analogues of nifedipine and diltiazem: an in vitro analysis 131
Interazioni e prodotti nelle reazioni fra elettrofili tiofenici e supernucleofili 130
On the Rearrangement in Dioxane/Water of (Z)-Arylhydrazones of 5-Amino-3-benzoyl-1,2,4-oxadiazole into (2-Aryl-5-phenyl-2H-1,2,3-triazol-4-yl)ureas: Substituent Effects on the Different Reaction Pathways 129
Reactivity in 7-benzyl-2,7-naphthyridine derivatives: Nucleophilic substitutions, rearrangements, heterocyclizations and related reactions 127
On the reactivity of nitrosoimidazoles with acids (the Cusmano–Ruccia reaction): a continuous source of new ring-into-ring interconversion 124
Understanding Oxadiazolothiazinone Biological Properties: Negative Inotropic Activity versus Cytochrome P450-Mediated Metabolism 124
A New Class of Selective Myocardial Calcium Channel Modulators: Oxadiazol-1-one Derivatives 122
Condensed 2-pyrrolidinone-1,2-oxazines from lithium enolate of 1-benzyl-5-oxo-pyrrolinecarboxylic acid and b-aryl, b-nitroenamines 119
Z-Phenylhydrazone of 3-Benzoil-5-Alkyl-1,2,4-Oxadiazole: Investigation of Behaviour in Solution and in Gas-Phase 119
4,6-dichloro-5-nitrobenzofuroxan: Different polymorphisms and dft investigation of its reactivity with nucleophiles 119
SEAr/SNAr Reactions between Trinitrothiophene Derivatives and Supernucleophiles at the Neutral Carbon Atom 118
Pursuing the challenge to detect labile intermediates in the SEAr/SNAr reaction: first evidence of Wheland-Meisenheimer complexes in thiophenic series 117
SINTESI DI OMO- ED ETERO-CICLI MEDIANTE PROCESSI DI APERTURA / CHIUSURA D’ANELLO A PARTIRE DA NITROTIOFENI 116
On the behaviour of (Z)-phenylhydrazones of some 5-alkyl-3-benzoyl-1,2,4-oxadiazoles in solution and in gas-phase: kinetic and spectrometric evidence in favour of self assembly 116
On the Nucleophilic Reactivity of 4,6-Dichloro-5-nitrobenzofuroxan with Some Aliphatic and Aromatic Amines: Selective nucleophilic substitution 115
L’ASSENZA DI SOLVATAZIONE PUÒ’ GIUSTIFICARE L’AUMENTO DELLA VELOCITA’ DEI PROCESSI DI INTERCONVERSIONE DI ANELLO IN LIQUIDI IONICI? 114
Study of Aromatic Nucleophilic Substitution with Amines on Nitrothiophenes in Room-Temperature Ionic Liquids: Are the Diffrent Effects on the Behavior of para-Like and ortho-Like Isomers on Going from Conventional Solvents to Room-Temperature Ionic Liquids Related to Solvatation Effects? 112
Preliminary Evaluation of Antitumor Activity of 1,4-bis(1-naphtyl)-2,3-dinitro-1,3-butadiene(naph-DNB) in Gastrointesinal Tumor Cell Lines 111
beta-Cyclodextrin as Host for the Rearrangement of Some Z-Hydrazones and Z-Phenylhydrazone of 3-Benzoil-5-X-1,2,4-Oxadiazoles 111
PURSUING THE CHALLENGE TO DETECT LABILE INTERMEDIATES IN THE SEAR/SNAR REACTION: FIRST EVIDENCE OF WHELAND-MEISENHEIMER INTERMEDIATES IN THIOPHENIC SERIES 109
The Effect of Ionic Liquids on the Rate of an Intramolecular Nucleophilic Substitution:The Study of Monocyclic Rearrangement of Heterocycles 108
OMO- ED ETERO-CICLI DA BUILDING-BLOCKS NITROVINILICI: NITROTIOCROMANI E TIOCROMANONI DAL 3-NITROBENZO[b]TIOFENE 106
Il ruolo della catena acetalica in derivati dell’ossadiazol-3-one: una nuova classe di modulatori dei canali del calcio 105
Reazione di 2-nitrotiofeni-4-sostituiti con ammine secondarie 105
ELETTROCICLIZZAZIONE ED ADDIZIONE DI MICHAEL: DICOTOMIA DI COMPORTAMENTO NEL PROCESSO DI CHIUSURA D’ANELLO DI BUILDING-BLOCKS NITROBUTADIENICI 104
Nitrobutadienes from β-nitrothiophenes: Valuable building-blocks in the overall ring-opening / ring-closure protocol to homo- or hetero-cycles. 104
Valutazione del contenuto di ammine adrenergiche nell’epicarpo di Citrus aurantium nelle varie fasi di maturazione 103
Rischi e benefici degli integratori anti-obesità a base di arance amare: il ruolo dell'analisi chimico-tossicologica 101
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On the application of the extended Fujita-Nishioka equation to polysubstitued system. A kinetic study of the rearrangement of several poly-substitued Z-arylhydrazones of 3-benzoyl-5-phenyl-1,2,4-oxadiazole into 2-aryl-4-benzoylamino-5-phenyl-1,2,3-triazoles in dioxane/water 100
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Comparative spectroscopic and electrochemical study of N-1 or N-2-alkylated 4-nitro and 7-nitroindazoles 97
Sintesi e Reattività di 5-alchil-3-benzoil-1,2,4-ossadiazoli 95
Methyl bis(2,2,2-trifluoroethyl) bromophosphonoacetate 94
Room Temperature Ionic Liquids Structure and its Effects on the Mononuclear Rearrangement of Heterocycles 87
Effect of Linear 5-alkyl Substituents on the Rearrangement Rate of the Z-Phenylhydrazone of Some 5-Alkyl-3-benzoil-1,2,4-oxadiazole 87
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Il ruolo della catena acetalica in derivati dell'ossadiazol-3-one: una nuova classe di modulatori dei canali del calcio 82
A Novel Approach to the Evaluation of the Importance of Steric and Electronic Effects in SNAr Reactions: A Computational, Thermodynamic and 1H and 13C NMR Study of "Meisenheimer-Type" Adducts in the Benzo[b]thiophene Series. 80
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Mononuclear rearrangements of heterocycles in water/-CD: information on the real site of reaction from structural modifications of substrates and from proton concentration dependence of the reactivity 71
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Substituent effects on the mechanism changeover in a multi-pathway reaction: a model for the behavior of biological system? 69
Strategies for improving the water solubility of new antitumour nitronaphthylbutadiene derivatives 66
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Totale 12.987
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Categoria #
all - tutte 33.869
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 33.869
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021848 0 0 0 0 0 99 22 94 100 86 77 370
2021/20221.605 180 60 126 114 150 90 32 103 71 98 278 303
2022/20231.978 217 305 111 222 151 160 53 108 322 34 204 91
2023/2024568 35 89 39 77 54 138 19 22 14 34 13 34
2024/20252.065 38 286 171 130 490 105 109 55 46 132 91 412
2025/20262.374 396 448 462 357 561 150 0 0 0 0 0 0
Totale 13.442