CRIS Current Research Information System

SPINELLI, DOMENICO
 Distribuzione geografica
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Continente #
NA - Nord America 5.735
AS - Asia 4.787
EU - Europa 4.246
AF - Africa 288
SA - Sud America 248
OC - Oceania 10
Continente sconosciuto - Info sul continente non disponibili 3
Totale 15.317
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Nazione #
US - Stati Uniti d'America 5.679
CN - Cina 1.421
SG - Singapore 1.316
VN - Vietnam 1.092
GB - Regno Unito 1.089
IT - Italia 736
DE - Germania 526
SE - Svezia 443
UA - Ucraina 386
FR - Francia 291
HK - Hong Kong 278
IN - India 234
RU - Federazione Russa 212
BR - Brasile 176
IE - Irlanda 133
NL - Olanda 107
JP - Giappone 99
ZA - Sudafrica 90
KR - Corea 89
EE - Estonia 68
JO - Giordania 66
CI - Costa d'Avorio 59
FI - Finlandia 57
TG - Togo 52
SC - Seychelles 45
BG - Bulgaria 44
BD - Bangladesh 35
BE - Belgio 35
CH - Svizzera 30
AR - Argentina 29
CA - Canada 29
PH - Filippine 22
HR - Croazia 17
MX - Messico 17
GR - Grecia 16
TH - Thailandia 15
IQ - Iraq 14
TR - Turchia 14
TW - Taiwan 14
ID - Indonesia 13
NG - Nigeria 13
CL - Cile 12
SA - Arabia Saudita 12
PL - Polonia 11
EC - Ecuador 10
ES - Italia 10
PK - Pakistan 9
CO - Colombia 8
LB - Libano 8
UZ - Uzbekistan 8
LT - Lituania 7
VE - Venezuela 7
AU - Australia 6
TN - Tunisia 6
CZ - Repubblica Ceca 5
EG - Egitto 5
CR - Costa Rica 4
IR - Iran 4
MA - Marocco 4
PS - Palestinian Territory 4
SI - Slovenia 4
AM - Armenia 3
DZ - Algeria 3
KE - Kenya 3
NZ - Nuova Zelanda 3
RO - Romania 3
A2 - ???statistics.table.value.countryCode.A2??? 2
AE - Emirati Arabi Uniti 2
AT - Austria 2
BO - Bolivia 2
BY - Bielorussia 2
ET - Etiopia 2
JM - Giamaica 2
LA - Repubblica Popolare Democratica del Laos 2
LK - Sri Lanka 2
MY - Malesia 2
PT - Portogallo 2
PY - Paraguay 2
AL - Albania 1
AO - Angola 1
AZ - Azerbaigian 1
BA - Bosnia-Erzegovina 1
CY - Cipro 1
DK - Danimarca 1
DO - Repubblica Dominicana 1
GA - Gabon 1
HU - Ungheria 1
IL - Israele 1
KG - Kirghizistan 1
KZ - Kazakistan 1
LV - Lettonia 1
LY - Libia 1
MD - Moldavia 1
MT - Malta 1
MU - Mauritius 1
MZ - Mozambico 1
NI - Nicaragua 1
NO - Norvegia 1
NP - Nepal 1
OM - Oman 1
Totale 15.306
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Città #
Southend 919
Singapore 859
Ashburn 476
Fairfield 468
Chandler 463
Santa Clara 361
Hefei 310
San Jose 288
Jacksonville 278
Hong Kong 264
Wilmington 240
Woodbridge 234
Ann Arbor 221
Ho Chi Minh City 208
Seattle 208
Princeton 194
Houston 192
Hanoi 185
Dong Ket 183
Beijing 166
Cambridge 157
Dublin 132
Boardman 123
Nanjing 101
Lauterbourg 97
Westminster 92
Tokyo 91
Turin 91
Padova 89
Bologna 82
Seoul 81
Los Angeles 80
The Dalles 80
Council Bluffs 75
Berlin 72
New York 68
Amman 66
Buffalo 60
Abidjan 59
Jinan 58
Dallas 57
Milan 54
Lomé 52
Helsinki 49
Saint Petersburg 43
Medford 42
Sofia 42
Shenyang 41
Rome 37
San Diego 37
Changsha 36
Brussels 35
Munich 34
Mülheim 34
Da Nang 33
Mahé 33
Tianjin 32
Guangzhou 27
Haiphong 27
Nanchang 24
Frankfurt am Main 23
Bengaluru 22
Redmond 22
Bern 21
Bremen 21
Hebei 21
Shanghai 21
London 20
Phoenix 20
Dearborn 18
Verona 18
Falkenstein 17
Redwood City 17
Olalla 16
Redondo Beach 16
São Paulo 16
Orem 15
Zhengzhou 15
Jiaxing 14
Washington 14
Hangzhou 13
Mountain View 13
Norwalk 13
San Francisco 13
Shenzhen 13
Yubileyny 13
Abeokuta 12
Chicago 12
Hải Dương 12
Biên Hòa 11
Des Moines 11
Haikou 11
Wuhan 11
Lanzhou 10
Montreal 10
Amsterdam 9
Bühl 9
Can Tho 9
Johannesburg 9
Naples 9
Totale 9.830
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Nome #
Sintesi di tioeteri, solfossidi, solfoni e tioesteri dei 3-aroil-4(Z)-[1-metil-2-sulfanil-vinil]-4H-[1,2,4]ossadiazol-5-oni e loro attività come calcio antagonisti 338
A new class of selective myocardial calcium channel modulators 2. Role of the acetal chain in oxadiazol-3-one derivatives 260
C-C coupling between trinitrothiophenes and triaminobenzenes: Zwitterionic intermediates and new all-conjugated structures 235
On the reactivity of some 2-methyleneindolines with b-nitroenamines, a-nitroalkenes, and 1,2-diaza-1,3-butadienes 215
Convergent results from experimental and theoretical DFT studies of the intramolecular rearrangement of Z-hydrazones of 3-acetyl-1,2,4-oxadiazoles 210
New Model for a Theoretical Density Functional Theory Investigation of the Mechanism of the Carbonic Anhydrase: How Does the Internal Bicarbonate Rearrangement Occur? 207
Can the absence of solvation of neutral reagents by ionic liquids be responsible for the high reactivity in base-assisted intramolecular nucleophilic substitutions in these solvents? 203
Absolute configuration and biological profile of two thiazinooxadiazol-3-ones with L-type calcium channel activity: a study of the structural effects 203
Analysis of the recent antipsychotic aripiprazole in human plasma by capillary electrophoresis and high performance liquid chromatography with diode array detection 203
Utilizzo dei Campi di Interazione Molecolare nella Ricerca di Molecole Biologicamente Attive 198
On the Dichotomic Behavior of the Z-2,4-Dinitrophenylhydrazone of 5-Amino-3-benzoyl-1,2,4-oxadiazole with Acids in Toluene and in Dioxane/Water: Rearrangement versus Hydrolisis 195
A multidisciplinary study of chemico-physical properties of different classes of 2-aryl-5(or 6)-nitrobenzimidazoles: NMR, electrochemical behavior, ESR, and DFT calculations 191
3-Aryl-4-nitrobenzothiochromans S,S-dioxide: From Calcium-Channel Modulators Properties to Multidrug-Resistance Reverting Activity 189
Catalytic Mechanism of Diaminopimelate Epimerase: A QM/MM Investigation 187
SINTESI DI COMPOSTI ETEROCICLICI MEDIANTE ESPANSIONE D’ANELLO DI NITROTIOFENI: 3-ARIL-2-FENIL-4-NITROTIOCROMANI S,S-DIOSSIDI DAL 3-NITROBENZO[b]TIOFENE 179
Calcium Antagonists Discovered by a Multidisciplinary Approach. 179
L-Type Calcium Channel Blockers: From Diltiazem to 1,2,4-Oxadiazol-5-ones via Thiazinooxadiazol-3-one Derivatives 179
Modellistica molecolare applicata a modulatori dei canali del calcio 177
The Catalytic Activity of Proline Racemase: a QM/MM Study 177
Computational QM/MM Study of the Reaction Mechanism of Human Glutathione S-Transferase A3-3 174
Easy access to 4-nitrothiochroman S.S-dioxides via ring-enlargement from 3-nitrobenzo[b]thiophene 173
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The Catalytic Activity of Diaminopimelate Epimerase: a QM/MM Study 170
Substituent effect on the electrochemical behaviour of some ortho-substituted (aryl)(2-nitrobenzo[b]thiophen-3-yl)amines. A combined experimental and computational study 169
Spectroscopic and electrochemical properties of 1- or 2-alkyl substituted 5- and 6-nitroindazoles 169
SINTESI DI COMPOSTI ETEROCICLICI MEDIANTE ESPANSIONE D’ANELLO DI NITROTIOFENI: 3-ARIL-4-NITROTIOCROMANI E 3-ARIL-4-TIOCROMANONI S,S-DIOSSIDI DAL 3-NITROBENZO[b]TIOFENE 168
TRASPOSIZIONI ETEROCICLICHE MONONUCLEARI. APPLICAZIONE DELL’EQUAZIONE DI FUJITA-NISHIOKA ALLA REATTIVITA’ DI Z FENILIDRAZONI DI- E POLI-SOSTITUITI DEL 3-BENZOIL-5-FENIL-1,2,4-OSSADIAZOLO 168
New calcium channel modilators discovered by virtual screening 167
Five-to-Six Membered Ring-rearrangements in the Reaction of 5-Perfluoroalkyl-1,2,4-oxadiazoles with Hydrazine and Methylhydrazine 167
The First Example of an Irreversible Ring-Degenerate Rearrangement on Five-Membered Heterocycles by Attack of an External Bidentate Nucleophile 166
Trinitrothiophenes/Tris(alkylamino)benzenes reactions: new insights on nucleophilic/electrophilic interaction 165
Electron Ionization Induced Fragmentation of some 3-Aroylamino-5-Methyl-1,2,4- Oxadiazoles and 3-Acetylamino-5-Aryl-1,2,4-Oxadiazoles 165
An Unexpected Pathway to Enantiomerization of Hemithioketals in Toluene Involving a Dimeric Transition State: A Combined Experimental and Computational Study 165
On the Nucleophilic Reactivity of 4,6-Dichloro-5-nitrobenzofuroxan with Some Aliphatic and Aromatic Amines: Selective nucleophilic substitution 162
Reactivity in 7-benzyl-2,7-naphthyridine derivatives: Nucleophilic substitutions, rearrangements, heterocyclizations and related reactions 161
Mononuclear Rearrangement of the Z-Phenylhydrazones of Some 3-Acyl-1,2,4-oxadiazoles: Effect of Substituents on the Nucleophilic Character of the >c=N-NH-C 6 H 5 Chain and on the Charge Density of N-2 of the 1,2,4-Oxadiazole Ring (Electrophilic Counterpart) 161
NUOVE TRASFORMAZIONI DI BUILDING-BLOCKS DINITROBUTADIENICI DERIVANTI DALL’APERTURA D’ANELLO DEL 3,4-DINITROTIOFENE 160
Interazioni e prodotti nelle reazioni fra elettrofili tiofenici e supernucleofili 160
STUDIO CINETICO DELLA TRASPOSIZIONE DI Z-FENILIDRAZONI POLISOSTITUITI DEL 3-BENZOIL-5-FENIL-1,2,4-OSSADIAZOLI NEI CORRISPONDENTI 2-ARIL-5-FENIL-1,2,3-TRIAZOLI IN H2O/DIOSSANO 159
Bis (2,2,2-trifluoroethyl) Chlorophosphate 159
REATTIVITA’ DEGLI Z-IDRAZONI, -SEMICARBAZONI E -FENILSEMICARBAZONI DEL 3 BENZOIL-5-FENIL-1,2,4-OSSADIAZOLO: EFFETTO DELLA STRUTTURA DELLA CATENA LATERALE 158
EFFETTI DELLA LUNGHEZZA DELLA CATENA ALCHILICA SULLA VELOCITA’ DI TRASPOSIZIONE DI ALCUNI Z-FENILIDRAZONI DI 5-ALCHILI-3-BENZOIL-1,2,4-OSSADIAZOLI 157
REATTIVITA’ DI Z-ARILIDRAZONI DEL 5-AMMINO-3-BENZOIL-1,2,4-OSSADIAZOLO IN PRESENZA DI ACIDO TRICLOROACETICO E DI PIPERIDINA IN TOLUENE: CONFRONTO CON I DATI IN DIOSSANO-ACQUA 156
SEAr/SNAr Reactions between Trinitrothiophene Derivatives and Supernucleophiles at the Neutral Carbon Atom 156
TRASPOSIZIONI MONONUCLEARI DI ETEROCICLI. REATTIVITA’ DI Z-ARILIDRAZONI DEL 5-AMMINO-3-BENZOIL-1,2,4-OSSADIAZOLO IN D/W: EFFETTO DEI SOSTITUENTI 155
NMR study of the (Z)-phenylhydrazones of 5-alkyl- and 5-aryl-3-benzoyl-1,2,4-oxadiazoles: Support for the interpretation of kinetic results on the rearrangement of 1,2,4-oxadiazoles to 1,2,3-triazoles. 155
Fluorinated heterocyclic compounds. An effective strategy for the synthesis of fluorinated Z-oximes of 3-perfluoroalkyl-6-phenyl-2H-1,2,4-triazin- 5-ones via a ring-enlargement reaction of 3-benzoyl-5-perfluoroalkyl-1,2,4-oxadiazoles and hydrazine. 154
Un approccio multidisciplinare per lo studio di modulatori di canali del Ca2+ di tipo-L 153
Nitroalkylation and nitroalkenylation reactions of g-lactone enolates. A facile ring switch from polysubstituted g-lactones to polysubstituted g-lactams 153
The Catalytic Activity of Proline Racemase: a QM/MM Study 153
Inhibition of cell proliferation, cytotoxicity and induction of apoptosis of 1,4-bis(1-naphthyl)-2,3-dinitro-1,3-butadiene in gastrointestinal tumour cell lines and preliminary evaluation of its toxicity in vivo. 151
Stereoselective Behavior of the Functional Diltiazem Analogue 1-[(4-Chlorophenyl)sulfonyl]-2-(2-thienyl)pyrrolidine, a New L-Type Calcium Channel Blocker 151
Discovery of novel and cardioselective diltiazem-like calcium channel blockers via virtual screening. 151
On the Rearrangement in Dioxane/Water of (Z)-Arylhydrazones of 5-Amino-3-benzoyl-1,2,4-oxadiazole into (2-Aryl-5-phenyl-2H-1,2,3-triazol-4-yl)ureas: Substituent Effects on the Different Reaction Pathways 151
Pursuing the challenge to detect labile intermediates in the SEAr/SNAr reaction: first evidence of Wheland-Meisenheimer complexes in thiophenic series 149
New classes of calcium channel modulators: thiazinooxadiazol-3-one and oxadiazol-5-one derivatives 148
On the reactivity of nitrosoimidazoles with acids (the Cusmano–Ruccia reaction): a continuous source of new ring-into-ring interconversion 148
Inhibition of MDR1 activity and induction of apoptosis by analogues of nifedipine and diltiazem: an in vitro analysis 148
4,6-dichloro-5-nitrobenzofuroxan: Different polymorphisms and dft investigation of its reactivity with nucleophiles 148
Z-Phenylhydrazone of 3-Benzoil-5-Alkyl-1,2,4-Oxadiazole: Investigation of Behaviour in Solution and in Gas-Phase 147
STEREOSELETTIVITÀ DI UNA BENZENSOLFONAMMIDE (M8), COME MODULATORE DEI CANALI DEL CALCIO DI TIPO-L 144
Condensed 2-pyrrolidinone-1,2-oxazines from lithium enolate of 1-benzyl-5-oxo-pyrrolinecarboxylic acid and b-aryl, b-nitroenamines 144
Understanding Oxadiazolothiazinone Biological Properties: Negative Inotropic Activity versus Cytochrome P450-Mediated Metabolism 143
ANTICANCER ACTIVITY OF 1,4-BIS(1-NAPHTHYL)-2,3-DINITRO-1,3-BUTADIENE:CURRENT STATE OF THE RESEARCH 142
On the behaviour of (Z)-phenylhydrazones of some 5-alkyl-3-benzoyl-1,2,4-oxadiazoles in solution and in gas-phase: kinetic and spectrometric evidence in favour of self assembly 142
PURSUING THE CHALLENGE TO DETECT LABILE INTERMEDIATES IN THE SEAR/SNAR REACTION: FIRST EVIDENCE OF WHELAND-MEISENHEIMER INTERMEDIATES IN THIOPHENIC SERIES 140
A New Class of Selective Myocardial Calcium Channel Modulators: Oxadiazol-1-one Derivatives 140
beta-Cyclodextrin as Host for the Rearrangement of Some Z-Hydrazones and Z-Phenylhydrazone of 3-Benzoil-5-X-1,2,4-Oxadiazoles 140
Comparative spectroscopic and electrochemical study of N-1 or N-2-alkylated 4-nitro and 7-nitroindazoles 135
SINTESI DI OMO- ED ETERO-CICLI MEDIANTE PROCESSI DI APERTURA / CHIUSURA D’ANELLO A PARTIRE DA NITROTIOFENI 131
Study of Aromatic Nucleophilic Substitution with Amines on Nitrothiophenes in Room-Temperature Ionic Liquids: Are the Diffrent Effects on the Behavior of para-Like and ortho-Like Isomers on Going from Conventional Solvents to Room-Temperature Ionic Liquids Related to Solvatation Effects? 129
L’ASSENZA DI SOLVATAZIONE PUÒ’ GIUSTIFICARE L’AUMENTO DELLA VELOCITA’ DEI PROCESSI DI INTERCONVERSIONE DI ANELLO IN LIQUIDI IONICI? 128
OMO- ED ETERO-CICLI DA BUILDING-BLOCKS NITROVINILICI: NITROTIOCROMANI E TIOCROMANONI DAL 3-NITROBENZO[b]TIOFENE 126
Nitrobutadienes from β-nitrothiophenes: Valuable building-blocks in the overall ring-opening / ring-closure protocol to homo- or hetero-cycles. 126
Preliminary Evaluation of Antitumor Activity of 1,4-bis(1-naphtyl)-2,3-dinitro-1,3-butadiene(naph-DNB) in Gastrointesinal Tumor Cell Lines 124
Rischi e benefici degli integratori anti-obesità a base di arance amare: il ruolo dell'analisi chimico-tossicologica 124
Reazione di 2-nitrotiofeni-4-sostituiti con ammine secondarie 124
The Effect of Ionic Liquids on the Rate of an Intramolecular Nucleophilic Substitution:The Study of Monocyclic Rearrangement of Heterocycles 123
Il ruolo della catena acetalica in derivati dell’ossadiazol-3-one: una nuova classe di modulatori dei canali del calcio 122
On the application of the extended Fujita-Nishioka equation to polysubstitued system. A kinetic study of the rearrangement of several poly-substitued Z-arylhydrazones of 3-benzoyl-5-phenyl-1,2,4-oxadiazole into 2-aryl-4-benzoylamino-5-phenyl-1,2,3-triazoles in dioxane/water 121
ELETTROCICLIZZAZIONE ED ADDIZIONE DI MICHAEL: DICOTOMIA DI COMPORTAMENTO NEL PROCESSO DI CHIUSURA D’ANELLO DI BUILDING-BLOCKS NITROBUTADIENICI 120
Valutazione del contenuto di ammine adrenergiche nell’epicarpo di Citrus aurantium nelle varie fasi di maturazione 115
Effect of Linear 5-alkyl Substituents on the Rearrangement Rate of the Z-Phenylhydrazone of Some 5-Alkyl-3-benzoil-1,2,4-oxadiazole 115
Methyl bis(2,2,2-trifluoroethyl) bromophosphonoacetate 107
Sintesi e Reattività di 5-alchil-3-benzoil-1,2,4-ossadiazoli 106
Mononuclear rearrangements of heterocycles in water/-CD: information on the real site of reaction from structural modifications of substrates and from proton concentration dependence of the reactivity 105
Room Temperature Ionic Liquids Structure and its Effects on the Mononuclear Rearrangement of Heterocycles 101
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A Novel Approach to the Evaluation of the Importance of Steric and Electronic Effects in SNAr Reactions: A Computational, Thermodynamic and 1H and 13C NMR Study of "Meisenheimer-Type" Adducts in the Benzo[b]thiophene Series. 100
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Il ruolo della catena acetalica in derivati dell'ossadiazol-3-one: una nuova classe di modulatori dei canali del calcio 96
Elucidating chemical reactivity and transition state of mononuclear rearrangement of heterocycles through the use o fcompartimentalized micellar media 91
Substituent effects on the mechanism changeover in a multi-pathway reaction: a model for the behavior of biological system? 91
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Strategies for improving the water solubility of new antitumour nitronaphthylbutadiene derivatives 76
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Isomerization and rearrangement of (E)- and (Z)-phenylhydrazones of 3-benzoyl-5-phenyl-1,2,4-oxadiazole: evidence for a “new” type of acid-catalysis by copper(II) salts in mononuclear rearrangement of heterocycles 74
Totale 15.005
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Categoria #
all - tutte 39.118
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 39.118
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021370 0 0 0 0 0 0 0 0 0 0 0 370
2021/20221.605 180 60 126 114 150 90 32 103 71 98 278 303
2022/20231.978 217 305 111 222 151 160 53 108 322 34 204 91
2023/2024568 35 89 39 77 54 138 19 22 14 34 13 34
2024/20252.065 38 286 171 130 490 105 109 55 46 132 91 412
2025/20264.487 396 448 462 357 561 321 398 182 848 253 151 110
Totale 15.555