CRIS Current Research Information System

SPINELLI, DOMENICO
 Distribuzione geografica
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Continente #
NA - Nord America 5.932
AS - Asia 4.807
EU - Europa 4.257
AF - Africa 288
SA - Sud America 252
Continente sconosciuto - Info sul continente non disponibili 241
OC - Oceania 10
Totale 15.787
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Nazione #
US - Stati Uniti d'America 5.850
CN - Cina 1.423
SG - Singapore 1.323
VN - Vietnam 1.092
GB - Regno Unito 1.089
IT - Italia 744
DE - Germania 526
SE - Svezia 443
UA - Ucraina 386
FR - Francia 292
HK - Hong Kong 284
IN - India 234
RU - Federazione Russa 212
BR - Brasile 178
IE - Irlanda 133
NL - Olanda 107
JP - Giappone 99
ZA - Sudafrica 90
KR - Corea 89
EE - Estonia 68
JO - Giordania 66
CI - Costa d'Avorio 59
FI - Finlandia 57
TG - Togo 52
SC - Seychelles 45
BG - Bulgaria 44
BD - Bangladesh 40
CA - Canada 38
BE - Belgio 35
CH - Svizzera 30
AR - Argentina 29
PH - Filippine 22
MX - Messico 19
HR - Croazia 17
GR - Grecia 16
TH - Thailandia 15
IQ - Iraq 14
TR - Turchia 14
TW - Taiwan 14
CL - Cile 13
ID - Indonesia 13
NG - Nigeria 13
SA - Arabia Saudita 12
ES - Italia 11
PL - Polonia 11
EC - Ecuador 10
CR - Costa Rica 9
PK - Pakistan 9
CO - Colombia 8
LB - Libano 8
LT - Lituania 8
UZ - Uzbekistan 8
JM - Giamaica 7
VE - Venezuela 7
AU - Australia 6
TN - Tunisia 6
CZ - Repubblica Ceca 5
EG - Egitto 5
IR - Iran 4
MA - Marocco 4
PS - Palestinian Territory 4
SI - Slovenia 4
AM - Armenia 3
DZ - Algeria 3
KE - Kenya 3
NI - Nicaragua 3
NZ - Nuova Zelanda 3
PY - Paraguay 3
RO - Romania 3
A2 - ???statistics.table.value.countryCode.A2??? 2
AE - Emirati Arabi Uniti 2
AT - Austria 2
BO - Bolivia 2
BY - Bielorussia 2
ET - Etiopia 2
LA - Repubblica Popolare Democratica del Laos 2
LK - Sri Lanka 2
MY - Malesia 2
PT - Portogallo 2
SV - El Salvador 2
AL - Albania 1
AO - Angola 1
AZ - Azerbaigian 1
BA - Bosnia-Erzegovina 1
CY - Cipro 1
DK - Danimarca 1
DO - Repubblica Dominicana 1
GA - Gabon 1
HN - Honduras 1
HU - Ungheria 1
IL - Israele 1
KG - Kirghizistan 1
KZ - Kazakistan 1
LV - Lettonia 1
LY - Libia 1
MD - Moldavia 1
MT - Malta 1
MU - Mauritius 1
MZ - Mozambico 1
NO - Norvegia 1
Totale 15.536
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Città #
Southend 919
Singapore 865
Ashburn 478
Fairfield 468
Chandler 463
Santa Clara 366
Hefei 310
San Jose 298
Jacksonville 278
Hong Kong 269
Wilmington 240
Woodbridge 234
Ann Arbor 221
Ho Chi Minh City 208
Seattle 208
Princeton 195
Houston 192
Hanoi 185
Dong Ket 183
Beijing 168
Cambridge 157
Council Bluffs 157
Dublin 132
Boardman 123
Nanjing 101
Lauterbourg 97
Westminster 92
Tokyo 91
Turin 91
Padova 89
Bologna 82
Seoul 81
Los Angeles 80
The Dalles 80
Berlin 72
New York 69
Amman 66
Buffalo 61
Abidjan 59
Jinan 58
Dallas 57
Milan 55
Lomé 52
Helsinki 49
Saint Petersburg 43
Medford 42
Sofia 42
Shenyang 41
Rome 38
San Diego 38
Changsha 36
Brussels 35
Munich 34
Mülheim 34
Da Nang 33
Mahé 33
Tianjin 32
Guangzhou 27
Haiphong 27
Phoenix 27
Nanchang 24
Frankfurt am Main 23
Bengaluru 22
Redmond 22
Bern 21
Bremen 21
Hebei 21
Shanghai 21
London 20
Dearborn 18
Verona 18
Falkenstein 17
Redwood City 17
Olalla 16
Redondo Beach 16
São Paulo 16
Orem 15
Washington 15
Zhengzhou 15
Jiaxing 14
Chicago 13
Hangzhou 13
Mountain View 13
Norwalk 13
San Francisco 13
Shenzhen 13
Yubileyny 13
Abeokuta 12
Hải Dương 12
Biên Hòa 11
Des Moines 11
Haikou 11
Wuhan 11
Lanzhou 10
Montreal 10
Amsterdam 9
Bühl 9
Can Tho 9
Johannesburg 9
Naples 9
Totale 9.957
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Nome #
Sintesi di tioeteri, solfossidi, solfoni e tioesteri dei 3-aroil-4(Z)-[1-metil-2-sulfanil-vinil]-4H-[1,2,4]ossadiazol-5-oni e loro attività come calcio antagonisti 342
A new class of selective myocardial calcium channel modulators 2. Role of the acetal chain in oxadiazol-3-one derivatives 262
C-C coupling between trinitrothiophenes and triaminobenzenes: Zwitterionic intermediates and new all-conjugated structures 237
On the reactivity of some 2-methyleneindolines with b-nitroenamines, a-nitroalkenes, and 1,2-diaza-1,3-butadienes 218
Convergent results from experimental and theoretical DFT studies of the intramolecular rearrangement of Z-hydrazones of 3-acetyl-1,2,4-oxadiazoles 214
Utilizzo dei Campi di Interazione Molecolare nella Ricerca di Molecole Biologicamente Attive 210
New Model for a Theoretical Density Functional Theory Investigation of the Mechanism of the Carbonic Anhydrase: How Does the Internal Bicarbonate Rearrangement Occur? 209
Can the absence of solvation of neutral reagents by ionic liquids be responsible for the high reactivity in base-assisted intramolecular nucleophilic substitutions in these solvents? 205
Absolute configuration and biological profile of two thiazinooxadiazol-3-ones with L-type calcium channel activity: a study of the structural effects 205
Analysis of the recent antipsychotic aripiprazole in human plasma by capillary electrophoresis and high performance liquid chromatography with diode array detection 205
On the Dichotomic Behavior of the Z-2,4-Dinitrophenylhydrazone of 5-Amino-3-benzoyl-1,2,4-oxadiazole with Acids in Toluene and in Dioxane/Water: Rearrangement versus Hydrolisis 196
3-Aryl-4-nitrobenzothiochromans S,S-dioxide: From Calcium-Channel Modulators Properties to Multidrug-Resistance Reverting Activity 193
A multidisciplinary study of chemico-physical properties of different classes of 2-aryl-5(or 6)-nitrobenzimidazoles: NMR, electrochemical behavior, ESR, and DFT calculations 192
Catalytic Mechanism of Diaminopimelate Epimerase: A QM/MM Investigation 187
SINTESI DI COMPOSTI ETEROCICLICI MEDIANTE ESPANSIONE D’ANELLO DI NITROTIOFENI: 3-ARIL-2-FENIL-4-NITROTIOCROMANI S,S-DIOSSIDI DAL 3-NITROBENZO[b]TIOFENE 180
L-Type Calcium Channel Blockers: From Diltiazem to 1,2,4-Oxadiazol-5-ones via Thiazinooxadiazol-3-one Derivatives 180
Modellistica molecolare applicata a modulatori dei canali del calcio 179
Calcium Antagonists Discovered by a Multidisciplinary Approach. 179
The Catalytic Activity of Proline Racemase: a QM/MM Study 179
Computational QM/MM Study of the Reaction Mechanism of Human Glutathione S-Transferase A3-3 176
Easy access to 4-nitrothiochroman S.S-dioxides via ring-enlargement from 3-nitrobenzo[b]thiophene 175
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Five-to-Six Membered Ring-rearrangements in the Reaction of 5-Perfluoroalkyl-1,2,4-oxadiazoles with Hydrazine and Methylhydrazine 172
The Catalytic Activity of Diaminopimelate Epimerase: a QM/MM Study 172
Spectroscopic and electrochemical properties of 1- or 2-alkyl substituted 5- and 6-nitroindazoles 171
Reactivity in 7-benzyl-2,7-naphthyridine derivatives: Nucleophilic substitutions, rearrangements, heterocyclizations and related reactions 170
Electron Ionization Induced Fragmentation of some 3-Aroylamino-5-Methyl-1,2,4- Oxadiazoles and 3-Acetylamino-5-Aryl-1,2,4-Oxadiazoles 170
SINTESI DI COMPOSTI ETEROCICLICI MEDIANTE ESPANSIONE D’ANELLO DI NITROTIOFENI: 3-ARIL-4-NITROTIOCROMANI E 3-ARIL-4-TIOCROMANONI S,S-DIOSSIDI DAL 3-NITROBENZO[b]TIOFENE 169
TRASPOSIZIONI ETEROCICLICHE MONONUCLEARI. APPLICAZIONE DELL’EQUAZIONE DI FUJITA-NISHIOKA ALLA REATTIVITA’ DI Z FENILIDRAZONI DI- E POLI-SOSTITUITI DEL 3-BENZOIL-5-FENIL-1,2,4-OSSADIAZOLO 169
Substituent effect on the electrochemical behaviour of some ortho-substituted (aryl)(2-nitrobenzo[b]thiophen-3-yl)amines. A combined experimental and computational study 169
New calcium channel modilators discovered by virtual screening 168
The First Example of an Irreversible Ring-Degenerate Rearrangement on Five-Membered Heterocycles by Attack of an External Bidentate Nucleophile 167
Trinitrothiophenes/Tris(alkylamino)benzenes reactions: new insights on nucleophilic/electrophilic interaction 167
An Unexpected Pathway to Enantiomerization of Hemithioketals in Toluene Involving a Dimeric Transition State: A Combined Experimental and Computational Study 166
On the Nucleophilic Reactivity of 4,6-Dichloro-5-nitrobenzofuroxan with Some Aliphatic and Aromatic Amines: Selective nucleophilic substitution 166
NUOVE TRASFORMAZIONI DI BUILDING-BLOCKS DINITROBUTADIENICI DERIVANTI DALL’APERTURA D’ANELLO DEL 3,4-DINITROTIOFENE 163
Mononuclear Rearrangement of the Z-Phenylhydrazones of Some 3-Acyl-1,2,4-oxadiazoles: Effect of Substituents on the Nucleophilic Character of the >c=N-NH-C 6 H 5 Chain and on the Charge Density of N-2 of the 1,2,4-Oxadiazole Ring (Electrophilic Counterpart) 163
Interazioni e prodotti nelle reazioni fra elettrofili tiofenici e supernucleofili 163
REATTIVITA’ DEGLI Z-IDRAZONI, -SEMICARBAZONI E -FENILSEMICARBAZONI DEL 3 BENZOIL-5-FENIL-1,2,4-OSSADIAZOLO: EFFETTO DELLA STRUTTURA DELLA CATENA LATERALE 161
STUDIO CINETICO DELLA TRASPOSIZIONE DI Z-FENILIDRAZONI POLISOSTITUITI DEL 3-BENZOIL-5-FENIL-1,2,4-OSSADIAZOLI NEI CORRISPONDENTI 2-ARIL-5-FENIL-1,2,3-TRIAZOLI IN H2O/DIOSSANO 161
Bis (2,2,2-trifluoroethyl) Chlorophosphate 161
EFFETTI DELLA LUNGHEZZA DELLA CATENA ALCHILICA SULLA VELOCITA’ DI TRASPOSIZIONE DI ALCUNI Z-FENILIDRAZONI DI 5-ALCHILI-3-BENZOIL-1,2,4-OSSADIAZOLI 160
Fluorinated heterocyclic compounds. An effective strategy for the synthesis of fluorinated Z-oximes of 3-perfluoroalkyl-6-phenyl-2H-1,2,4-triazin- 5-ones via a ring-enlargement reaction of 3-benzoyl-5-perfluoroalkyl-1,2,4-oxadiazoles and hydrazine. 159
REATTIVITA’ DI Z-ARILIDRAZONI DEL 5-AMMINO-3-BENZOIL-1,2,4-OSSADIAZOLO IN PRESENZA DI ACIDO TRICLOROACETICO E DI PIPERIDINA IN TOLUENE: CONFRONTO CON I DATI IN DIOSSANO-ACQUA 158
NMR study of the (Z)-phenylhydrazones of 5-alkyl- and 5-aryl-3-benzoyl-1,2,4-oxadiazoles: Support for the interpretation of kinetic results on the rearrangement of 1,2,4-oxadiazoles to 1,2,3-triazoles. 158
SEAr/SNAr Reactions between Trinitrothiophene Derivatives and Supernucleophiles at the Neutral Carbon Atom 158
TRASPOSIZIONI MONONUCLEARI DI ETEROCICLI. REATTIVITA’ DI Z-ARILIDRAZONI DEL 5-AMMINO-3-BENZOIL-1,2,4-OSSADIAZOLO IN D/W: EFFETTO DEI SOSTITUENTI 157
Nitroalkylation and nitroalkenylation reactions of g-lactone enolates. A facile ring switch from polysubstituted g-lactones to polysubstituted g-lactams 155
On the Rearrangement in Dioxane/Water of (Z)-Arylhydrazones of 5-Amino-3-benzoyl-1,2,4-oxadiazole into (2-Aryl-5-phenyl-2H-1,2,3-triazol-4-yl)ureas: Substituent Effects on the Different Reaction Pathways 155
Inhibition of cell proliferation, cytotoxicity and induction of apoptosis of 1,4-bis(1-naphthyl)-2,3-dinitro-1,3-butadiene in gastrointestinal tumour cell lines and preliminary evaluation of its toxicity in vivo. 154
Un approccio multidisciplinare per lo studio di modulatori di canali del Ca2+ di tipo-L 154
The Catalytic Activity of Proline Racemase: a QM/MM Study 154
Discovery of novel and cardioselective diltiazem-like calcium channel blockers via virtual screening. 153
On the reactivity of nitrosoimidazoles with acids (the Cusmano–Ruccia reaction): a continuous source of new ring-into-ring interconversion 152
Stereoselective Behavior of the Functional Diltiazem Analogue 1-[(4-Chlorophenyl)sulfonyl]-2-(2-thienyl)pyrrolidine, a New L-Type Calcium Channel Blocker 151
Pursuing the challenge to detect labile intermediates in the SEAr/SNAr reaction: first evidence of Wheland-Meisenheimer complexes in thiophenic series 151
New classes of calcium channel modulators: thiazinooxadiazol-3-one and oxadiazol-5-one derivatives 150
Inhibition of MDR1 activity and induction of apoptosis by analogues of nifedipine and diltiazem: an in vitro analysis 150
Z-Phenylhydrazone of 3-Benzoil-5-Alkyl-1,2,4-Oxadiazole: Investigation of Behaviour in Solution and in Gas-Phase 149
4,6-dichloro-5-nitrobenzofuroxan: Different polymorphisms and dft investigation of its reactivity with nucleophiles 149
STEREOSELETTIVITÀ DI UNA BENZENSOLFONAMMIDE (M8), COME MODULATORE DEI CANALI DEL CALCIO DI TIPO-L 147
Condensed 2-pyrrolidinone-1,2-oxazines from lithium enolate of 1-benzyl-5-oxo-pyrrolinecarboxylic acid and b-aryl, b-nitroenamines 146
A New Class of Selective Myocardial Calcium Channel Modulators: Oxadiazol-1-one Derivatives 146
Understanding Oxadiazolothiazinone Biological Properties: Negative Inotropic Activity versus Cytochrome P450-Mediated Metabolism 145
On the behaviour of (Z)-phenylhydrazones of some 5-alkyl-3-benzoyl-1,2,4-oxadiazoles in solution and in gas-phase: kinetic and spectrometric evidence in favour of self assembly 145
beta-Cyclodextrin as Host for the Rearrangement of Some Z-Hydrazones and Z-Phenylhydrazone of 3-Benzoil-5-X-1,2,4-Oxadiazoles 144
ANTICANCER ACTIVITY OF 1,4-BIS(1-NAPHTHYL)-2,3-DINITRO-1,3-BUTADIENE:CURRENT STATE OF THE RESEARCH 143
PURSUING THE CHALLENGE TO DETECT LABILE INTERMEDIATES IN THE SEAR/SNAR REACTION: FIRST EVIDENCE OF WHELAND-MEISENHEIMER INTERMEDIATES IN THIOPHENIC SERIES 142
Comparative spectroscopic and electrochemical study of N-1 or N-2-alkylated 4-nitro and 7-nitroindazoles 137
SINTESI DI OMO- ED ETERO-CICLI MEDIANTE PROCESSI DI APERTURA / CHIUSURA D’ANELLO A PARTIRE DA NITROTIOFENI 132
Study of Aromatic Nucleophilic Substitution with Amines on Nitrothiophenes in Room-Temperature Ionic Liquids: Are the Diffrent Effects on the Behavior of para-Like and ortho-Like Isomers on Going from Conventional Solvents to Room-Temperature Ionic Liquids Related to Solvatation Effects? 131
L’ASSENZA DI SOLVATAZIONE PUÒ’ GIUSTIFICARE L’AUMENTO DELLA VELOCITA’ DEI PROCESSI DI INTERCONVERSIONE DI ANELLO IN LIQUIDI IONICI? 130
OMO- ED ETERO-CICLI DA BUILDING-BLOCKS NITROVINILICI: NITROTIOCROMANI E TIOCROMANONI DAL 3-NITROBENZO[b]TIOFENE 128
Nitrobutadienes from β-nitrothiophenes: Valuable building-blocks in the overall ring-opening / ring-closure protocol to homo- or hetero-cycles. 127
Preliminary Evaluation of Antitumor Activity of 1,4-bis(1-naphtyl)-2,3-dinitro-1,3-butadiene(naph-DNB) in Gastrointesinal Tumor Cell Lines 126
Rischi e benefici degli integratori anti-obesità a base di arance amare: il ruolo dell'analisi chimico-tossicologica 126
The Effect of Ionic Liquids on the Rate of an Intramolecular Nucleophilic Substitution:The Study of Monocyclic Rearrangement of Heterocycles 125
Reazione di 2-nitrotiofeni-4-sostituiti con ammine secondarie 125
On the application of the extended Fujita-Nishioka equation to polysubstitued system. A kinetic study of the rearrangement of several poly-substitued Z-arylhydrazones of 3-benzoyl-5-phenyl-1,2,4-oxadiazole into 2-aryl-4-benzoylamino-5-phenyl-1,2,3-triazoles in dioxane/water 125
Il ruolo della catena acetalica in derivati dell’ossadiazol-3-one: una nuova classe di modulatori dei canali del calcio 123
Effect of Linear 5-alkyl Substituents on the Rearrangement Rate of the Z-Phenylhydrazone of Some 5-Alkyl-3-benzoil-1,2,4-oxadiazole 122
ELETTROCICLIZZAZIONE ED ADDIZIONE DI MICHAEL: DICOTOMIA DI COMPORTAMENTO NEL PROCESSO DI CHIUSURA D’ANELLO DI BUILDING-BLOCKS NITROBUTADIENICI 121
Valutazione del contenuto di ammine adrenergiche nell’epicarpo di Citrus aurantium nelle varie fasi di maturazione 116
Methyl bis(2,2,2-trifluoroethyl) bromophosphonoacetate 111
Sintesi e Reattività di 5-alchil-3-benzoil-1,2,4-ossadiazoli 108
Mononuclear rearrangements of heterocycles in water/-CD: information on the real site of reaction from structural modifications of substrates and from proton concentration dependence of the reactivity 108
Room Temperature Ionic Liquids Structure and its Effects on the Mononuclear Rearrangement of Heterocycles 102
A Novel Approach to the Evaluation of the Importance of Steric and Electronic Effects in SNAr Reactions: A Computational, Thermodynamic and 1H and 13C NMR Study of "Meisenheimer-Type" Adducts in the Benzo[b]thiophene Series. 101
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Il ruolo della catena acetalica in derivati dell'ossadiazol-3-one: una nuova classe di modulatori dei canali del calcio 97
Substituent effects on the mechanism changeover in a multi-pathway reaction: a model for the behavior of biological system? 93
Elucidating chemical reactivity and transition state of mononuclear rearrangement of heterocycles through the use o fcompartimentalized micellar media 92
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Ru(bpy)2Cl2: A catalyst able to shift the course of the photorearrangement in the Boulton-Katritzky reaction 79
Strategies for improving the water solubility of new antitumour nitronaphthylbutadiene derivatives 77
Isomerization and rearrangement of (E)- and (Z)-phenylhydrazones of 3-benzoyl-5-phenyl-1,2,4-oxadiazole: evidence for a “new” type of acid-catalysis by copper(II) salts in mononuclear rearrangement of heterocycles 77
Totale 15.226
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Categoria #
all - tutte 40.615
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 40.615
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.425 0 60 126 114 150 90 32 103 71 98 278 303
2022/20231.978 217 305 111 222 151 160 53 108 322 34 204 91
2023/2024568 35 89 39 77 54 138 19 22 14 34 13 34
2024/20252.065 38 286 171 130 490 105 109 55 46 132 91 412
2025/20264.490 396 448 462 357 561 321 398 182 848 253 151 113
2026/2027229 80 149 0 0 0 0 0 0 0 0 0 0
Totale 15.787