CAVALLI, ANDREA
CAVALLI, ANDREA
FABIT - DIPARTIMENTO DI FARMACIA E BIOTECNOLOGIE
Docenti di ruolo di Ia fascia
Cavalli, ANDREA
The mechanistic understanding of the BRCA2-RAD51 interaction: an integrated structural biophysics study
2025 Rinaldi, F.; Bernetti, M.; Bresciani, V.; Veronesi, M.; Masetti, M.; Girotto, S.; Cavalli, A.
The mechanistic understanding of the BRCA2-RAD51 interaction: an integrated structural biophysics study
2025 Rinaldi, F.; Bernetti, M.; Bresciani, V.; Veronesi, M.; Masetti, M.; Girotto, S.; Cavalli, A.
A journey through targeting BRCA2-RAD51 protein-protein interaction to establish synthetic lethality as paradigm for anticancer drug discovery
2024 Bagnolini G., Poppi L., Previtali V., Ferrandi G., Rinaldi F., Girotto S., Hirsch A.K.H., Roberti M., Cavalli A.
An integrative structural study of the human full-length RAD52 at 2.2 Å resolution
2024 Balboni, Beatrice; Marotta, Roberto; Rinaldi, Francesco; Milordini, Giulia; Varignani, Giulia; Girotto, Stefania; Cavalli, Andrea
Improving deep neural network generalization and robustness to background bias via layer-wise relevance propagation optimization
2024 Bassi P.R.A.S.; Dertkigil S.S.J.; Cavalli A.
Machine learning for precision diagnostics of autoimmunity
2024 Kruta, J.; Carapito, R.; Trendelenburg, M.; Martin, T.; Rizzi, M.; Voll, R. E.; Cavalli, A.; Natali, E.; Meier, P.; Stawiski, M.; Mosbacher, J.; Mollet, A.; Santoro, A.; Capri, M.; Giampieri, E.; Schkommodau, E.; Miho, E.
New Horizons of Synthetic Lethality in Cancer: Current Development and Future Perspectives
2024 Previtali, Viola; Bagnolini, Greta; Ciamarone, Andrea; Ferrandi, Giovanni; Rinaldi, Francesco; Myers, Samuel Harry; Roberti, Marinella; Cavalli, Andrea
A RAD51/BRCA2 small molecule inhibitor enhances the antineoplastic effect of the PARPi talazoparib in pancreatic cancer
2023 Laura Poppi, Samuel H Myers, Viola Previtali, Francesco Rinaldi, Fulvia Farabegoli, Giuseppina Di Stefano, Naomi Walsh, Marinella Roberti, Andrea Cavalli
An 19F NMR fragment-based approach for the discovery and development of BRCA2-RAD51 inhibitors to pursuit synthetic lethality in combination with PARP inhibition in pancreatic cancer
2023 Myers, S. H.; Poppi, L.; Rinaldi, F.; Veronesi, M.; Ciamarone, A.; Previtali, V.; Bagnolini, G.; Schipani, F.; Ortega Martínez, J. A.; Girotto, S.; Di Stefano, G.; Farabegoli, F.; Walsh, N.; De Franco, F.; Roberti, M.; Cavalli, A.
Dissecting the BRCA2 - RAD51 interaction by integrating computational and experimental biophysics
2023 Rinaldi F., Bernetti M., Bresciani V., Girotto S., Cavalli A.
Elucidating the BRCA2 - RAD51 interaction by integrating computational and experimental biophysics
2023 Rinaldi F., Bernetti M., Bresciani V., Girotto S., Cavalli A.
Elucidating the BRCA2-RAD51 interaction through an integrated structural biophysics approach
2023 Rinaldi Francesco, Girotto Stefania, Cavalli Andrea
Galantamine-memantine hybrids for Alzheimer's disease: The influence of linker rigidity in biological activity and pharmacokinetic properties
2023 Basagni, Filippo; Ortega, Jose A; Bertozzi, Sine M; Armirotti, Andrea; Summa, Maria; Bertorelli, Rosalia; Bartolini, Manuela; Mellor, Ian R; Bedeschi, Martina; Bottegoni, Giovanni; Lembo, Vittorio; Minarini, Anna; Cavalli, Andrea; Rosini, Michela
Innovative Strategy toward Mutant CFTR Rescue in Cystic Fibrosis: Design and Synthesis of Thiadiazole Inhibitors of the E3 Ligase RNF5
2023 Brusa, Irene; Sondo, Elvira; Pesce, Emanuela; Tomati, Valeria; Gioia, Dario; Falchi, Federico; Balboni, Beatrice; Ortega Martínez, Jose Antonio; Veronesi, Marina; Romeo, Elisa; Margaroli, Natasha; Recanatini, Maurizio; Girotto, Stefania; Pedemonte, Nicoletta; Roberti, Marinella; Cavalli, Andrea
Integration of computational and experimental biophysics reveals novel insights on the BRCA2 - RAD51 interaction
2023 Rinaldi F., Bernetti M., Bresciani V., Girotto S., Cavalli A.
Isolation and Characterization of Monomeric Human RAD51: A Novel Tool for Investigating Homologous Recombination in Cancer
2023 Rinaldi F., Schipani F., Balboni B., Catalano F., Marotta R., Myers S. H., Previtali V., Veronesi M., Scietti L., Cecatiello V., Pasqualato S., Ortega J. A., Girotto S., Cavalli A.
Novel Insights into RAD52’s Structure, Function, and Druggability for Synthetic Lethality and Innovative Anticancer Therapies
2023 Balboni B.; Rinaldi F.; Previtali V.; Ciamarone A.; Girotto S.; Cavalli A.
On the allosteric puzzle and pocket crosstalk through computational means
2023 Aguti R.; Bernetti M.; Bosio S.; Decherchi S.; Cavalli A.
Optimal Transport for Free Energy Estimation
2023 Decherchi, S.; Cavalli, A.
Preomic profile of BxPC-3 cells after treatment with BRC4
2023 Previtali V.; Myers S.H.; Poppi L.; Wynne K.; Casamassima I.; Girotto S.; Di Stefano G.; Farabegoli F.; Roberti M.; Oliviero G.; Cavalli A.
| Titolo | Autore(i) | Anno | Periodico | Editore | Tipo | File |
|---|---|---|---|---|---|---|
| The mechanistic understanding of the BRCA2-RAD51 interaction: an integrated structural biophysics study | Rinaldi, F.; Bernetti, M.; Bresciani, V.; Veronesi, M.; Masetti, M.; Girotto, S.; Cavalli, A. | 2025-01-01 | - | - | 4.03 Poster | - |
| The mechanistic understanding of the BRCA2-RAD51 interaction: an integrated structural biophysics study | Rinaldi, F.; Bernetti, M.; Bresciani, V.; Veronesi, M.; Masetti, M.; Girotto, S.; Cavalli, A. | 2025-01-01 | - | - | 4.03 Poster | - |
| A journey through targeting BRCA2-RAD51 protein-protein interaction to establish synthetic lethality as paradigm for anticancer drug discovery | Bagnolini G., Poppi L., Previtali V., Ferrandi G., Rinaldi F., Girotto S., Hirsch A.K.H., Roberti... M., Cavalli A. | 2024-01-01 | - | - | 4.01 Contributo in Atti di convegno | - |
| An integrative structural study of the human full-length RAD52 at 2.2 Å resolution | Balboni, Beatrice; Marotta, Roberto; Rinaldi, Francesco; Milordini, Giulia; Varignani, Giulia; Gi...rotto, Stefania; Cavalli, Andrea | 2024-01-01 | COMMUNICATIONS BIOLOGY | - | 1.01 Articolo in rivista | - |
| Improving deep neural network generalization and robustness to background bias via layer-wise relevance propagation optimization | Bassi P.R.A.S.; Dertkigil S.S.J.; Cavalli A. | 2024-01-01 | NATURE COMMUNICATIONS | - | 1.01 Articolo in rivista | Nat_Commun.pdf |
| Machine learning for precision diagnostics of autoimmunity | Kruta, J.; Carapito, R.; Trendelenburg, M.; Martin, T.; Rizzi, M.; Voll, R. E.; Cavalli, A.; Nata...li, E.; Meier, P.; Stawiski, M.; Mosbacher, J.; Mollet, A.; Santoro, A.; Capri, M.; Giampieri, E.; Schkommodau, E.; Miho, E. | 2024-01-01 | SCIENTIFIC REPORTS | - | 1.01 Articolo in rivista | - |
| New Horizons of Synthetic Lethality in Cancer: Current Development and Future Perspectives | Previtali, Viola; Bagnolini, Greta; Ciamarone, Andrea; Ferrandi, Giovanni; Rinaldi, Francesco; My...ers, Samuel Harry; Roberti, Marinella; Cavalli, Andrea | 2024-01-01 | JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
| A RAD51/BRCA2 small molecule inhibitor enhances the antineoplastic effect of the PARPi talazoparib in pancreatic cancer | Laura Poppi, Samuel H Myers, Viola Previtali, Francesco Rinaldi, Fulvia Farabegoli, Giuseppina Di... Stefano, Naomi Walsh, Marinella Roberti, Andrea Cavalli | 2023-01-01 | - | FEBS PRESS | 4.03 Poster | - |
| An 19F NMR fragment-based approach for the discovery and development of BRCA2-RAD51 inhibitors to pursuit synthetic lethality in combination with PARP inhibition in pancreatic cancer | Myers, S. H.; Poppi, L.; Rinaldi, F.; Veronesi, M.; Ciamarone, A.; Previtali, V.; Bagnolini, G.; ...Schipani, F.; Ortega Martínez, J. A.; Girotto, S.; Di Stefano, G.; Farabegoli, F.; Walsh, N.; De Franco, F.; Roberti, M.; Cavalli, A. | 2023-01-01 | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | 1-s2.0-S0223523423010814-mmc1.docx; 1-s2.0-S0223523423010814-main.pdf |
| Dissecting the BRCA2 - RAD51 interaction by integrating computational and experimental biophysics | Rinaldi F., Bernetti M., Bresciani V., Girotto S., Cavalli A. | 2023-01-01 | - | - | 4.03 Poster | - |
| Elucidating the BRCA2 - RAD51 interaction by integrating computational and experimental biophysics | Rinaldi F., Bernetti M., Bresciani V., Girotto S., Cavalli A. | 2023-01-01 | - | - | 4.02 Riassunto (Abstract) | - |
| Elucidating the BRCA2-RAD51 interaction through an integrated structural biophysics approach | Rinaldi Francesco, Girotto Stefania, Cavalli Andrea | 2023-01-01 | - | - | 4.02 Riassunto (Abstract) | - |
| Galantamine-memantine hybrids for Alzheimer's disease: The influence of linker rigidity in biological activity and pharmacokinetic properties | Basagni, Filippo; Ortega, Jose A; Bertozzi, Sine M; Armirotti, Andrea; Summa, Maria; Bertorelli, ...Rosalia; Bartolini, Manuela; Mellor, Ian R; Bedeschi, Martina; Bottegoni, Giovanni; Lembo, Vittorio; Minarini, Anna; Cavalli, Andrea; Rosini, Michela | 2023-01-01 | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | Eur. J. Med.Chem. 2023.pdf; 1-s2.0-S0223523423007705-mmc1.docx |
| Innovative Strategy toward Mutant CFTR Rescue in Cystic Fibrosis: Design and Synthesis of Thiadiazole Inhibitors of the E3 Ligase RNF5 | Brusa, Irene; Sondo, Elvira; Pesce, Emanuela; Tomati, Valeria; Gioia, Dario; Falchi, Federico; Ba...lboni, Beatrice; Ortega Martínez, Jose Antonio; Veronesi, Marina; Romeo, Elisa; Margaroli, Natasha; Recanatini, Maurizio; Girotto, Stefania; Pedemonte, Nicoletta; Roberti, Marinella; Cavalli, Andrea | 2023-01-01 | JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | brusa-et-al-2023-innovative-strategy-toward-mutant-cftr-rescue-in-cystic-fibrosis-design-and-synthesis-of-thiadiazole.pdf |
| Integration of computational and experimental biophysics reveals novel insights on the BRCA2 - RAD51 interaction | Rinaldi F., Bernetti M., Bresciani V., Girotto S., Cavalli A. | 2023-01-01 | - | - | 4.03 Poster | - |
| Isolation and Characterization of Monomeric Human RAD51: A Novel Tool for Investigating Homologous Recombination in Cancer | Rinaldi F., Schipani F., Balboni B., Catalano F., Marotta R., Myers S. H., Previtali V., Veronesi... M., Scietti L., Cecatiello V., Pasqualato S., Ortega J. A., Girotto S., Cavalli A. | 2023-01-01 | ANGEWANDTE CHEMIE. INTERNATIONAL EDITION | - | 1.01 Articolo in rivista | Angew Chem Int Ed - 2023 - Rinaldi - Isolation and Characterization of Monomeric Human RAD51 A Novel Tool for-1.pdf |
| Novel Insights into RAD52’s Structure, Function, and Druggability for Synthetic Lethality and Innovative Anticancer Therapies | Balboni B.; Rinaldi F.; Previtali V.; Ciamarone A.; Girotto S.; Cavalli A. | 2023-01-01 | CANCERS | - | 1.01 Articolo in rivista | IRIS CRIS.pdf |
| On the allosteric puzzle and pocket crosstalk through computational means | Aguti R.; Bernetti M.; Bosio S.; Decherchi S.; Cavalli A. | 2023-01-01 | JOURNAL OF CHEMICAL PHYSICS ONLINE | - | 1.01 Articolo in rivista | - |
| Optimal Transport for Free Energy Estimation | Decherchi, S.; Cavalli, A. | 2023-01-01 | THE JOURNAL OF PHYSICAL CHEMISTRY LETTERS | - | 1.01 Articolo in rivista | - |
| Preomic profile of BxPC-3 cells after treatment with BRC4 | Previtali V.; Myers S.H.; Poppi L.; Wynne K.; Casamassima I.; Girotto S.; Di Stefano G.; Farabego...li F.; Roberti M.; Oliviero G.; Cavalli A. | 2023-01-01 | JOURNAL OF PROTEOMICS | - | 1.01 Articolo in rivista | manuscript_jprot_revised_second round_clean (1).docx |