CRIS Current Research Information System

CAVALLI, ANDREA
 Distribuzione geografica
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Continente #
NA - Nord America 11868
EU - Europa 8475
AS - Asia 3041
AF - Africa 592
SA - Sud America 42
Continente sconosciuto - Info sul continente non disponibili 20
OC - Oceania 14
Totale 24052
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Nazione #
US - Stati Uniti d'America 11832
GB - Regno Unito 2750
IT - Italia 1488
CN - Cina 1217
VN - Vietnam 1071
DE - Germania 970
SE - Svezia 798
UA - Ucraina 758
IN - India 536
IE - Irlanda 447
FR - Francia 386
RU - Federazione Russa 334
TG - Togo 224
EE - Estonia 205
ZA - Sudafrica 201
HR - Croazia 101
JO - Giordania 100
SC - Seychelles 60
CI - Costa d'Avorio 54
BE - Belgio 48
NG - Nigeria 45
JP - Giappone 31
GR - Grecia 30
BR - Brasile 28
CH - Svizzera 27
ES - Italia 27
CA - Canada 25
PL - Polonia 20
RO - Romania 18
EU - Europa 17
IR - Iran 17
NL - Olanda 15
AU - Australia 13
FI - Finlandia 13
CL - Cile 11
AT - Austria 9
LB - Libano 9
TR - Turchia 9
BZ - Belize 8
HK - Hong Kong 8
KR - Corea 7
PT - Portogallo 6
BG - Bulgaria 5
MY - Malesia 5
SG - Singapore 5
LV - Lettonia 4
NO - Norvegia 4
A2 - ???statistics.table.value.countryCode.A2??? 3
BD - Bangladesh 3
CZ - Repubblica Ceca 3
HU - Ungheria 3
ID - Indonesia 3
MD - Moldavia 3
MX - Messico 3
UZ - Uzbekistan 3
EG - Egitto 2
IL - Israele 2
IQ - Iraq 2
LK - Sri Lanka 2
MU - Mauritius 2
NA - Namibia 2
PH - Filippine 2
PK - Pakistan 2
AE - Emirati Arabi Uniti 1
AM - Armenia 1
BA - Bosnia-Erzegovina 1
BO - Bolivia 1
CO - Colombia 1
DK - Danimarca 1
KW - Kuwait 1
KZ - Kazakistan 1
LA - Repubblica Popolare Democratica del Laos 1
MA - Marocco 1
NZ - Nuova Zelanda 1
PE - Perù 1
SA - Arabia Saudita 1
SK - Slovacchia (Repubblica Slovacca) 1
SN - Senegal 1
TW - Taiwan 1
Totale 24052
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Città #
Southend 2490
Fairfield 1945
Chandler 983
Woodbridge 946
Wilmington 865
Ashburn 864
Seattle 847
Houston 804
Ann Arbor 740
Dong Ket 718
Cambridge 658
Princeton 626
Jacksonville 490
Dublin 446
Bologna 370
Westminster 261
Nanjing 253
Padova 241
Lomé 224
Berlin 194
Saint Petersburg 133
Jinan 119
San Diego 115
Shenyang 113
Redmond 109
Amman 100
Hebei 92
Nanchang 87
Medford 83
Changsha 75
Beijing 73
Boardman 71
Falls Church 71
Milan 66
Tianjin 61
Des Moines 57
Abidjan 54
Dearborn 52
Norwalk 51
Mahé 50
Brussels 47
Abeokuta 43
Olalla 41
Redwood City 38
Verona 35
Jiaxing 34
Zhengzhou 33
Haikou 28
Ningbo 27
Genova 26
Guangzhou 26
Hangzhou 26
Lanzhou 26
Tokyo 25
Rome 23
Fremont 21
Bremen 20
Chicago 20
Kunming 20
Taiyuan 20
Taizhou 19
Phoenix 18
London 17
San Jose 17
San Venanzo 17
Bari 15
Frankfurt am Main 14
Modena 12
Boydton 11
Frankfurt Am Main 11
Helsinki 11
Paris 11
Ferrara 10
Fuzhou 10
Hefei 10
Lausanne 10
Buffalo 9
Montréal 9
Napoli 9
Parma 9
Belize City 8
Costa Mesa 8
Leawood 8
Mountain View 8
Scuola 8
São Paulo 8
Toronto 8
Zanjan 8
Barcelona 7
New York 7
Plauen 7
Siracusa 7
Camisano Vicentino 6
Genoa 6
Imola 6
Kiev 6
Las Vegas 6
Serra 6
Torino 6
Andover 5
Totale 17564
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Nome #
3,4-Dihydro-1,3,5-triazin-2(1H)-ones as the First Dual BACE-1/GSK-3β Fragment Hits against Alzheimer's Disease 207
The 1,2,4-Triazolo[4,3-a]pyrazin-3-one as a Versatile Scaffold for the Design of Potent Adenosine Human Receptor Antagonists. Structural Investigations to Target the A2AReceptor Subtype 206
La metadinamica nello studio dell'energia libera di complessi recettoriali binari 183
A small chemical library of 2-aminoimidazole derivatives as BACE-1 inhibitors: structure-based design, synthesis, and biological evaluation 174
Multitarget Strategy to Address Alzheimer's Disease: Design, Synthesis, Biological Evaluation, and Computational Studies of Coumarin-Based Derivatives 162
A Catalytic Mechanism for Cysteine N-Terminal Nucleophile Hydrolases, as Revealed by Free Energy Simulations 158
An automated docking protocol for HERG channel blockers. 157
Cholinesterase inhibitors: xanthostigmine derivatives blocking the acetylcholinesterase-induced beta-amyloid aggregation. 156
A molecular dynamics study of reovirus attachment protein sigma1 reveals conformational changes in sigma1 structure 154
A small molecule targeting the multifactorial nature of Alzheimer's disease 151
Computational design and discovery of "minimally structured" hERG blockers. 151
Synthetic Lethality in Pancreatic Cancer: Discovery of a New RAD51-BRCA2 Small Molecule Disruptor That Inhibits Homologous Recombination and Synergizes with Olaparib 149
Rad51/Brca2 Disruptors Inhibit Homologous Recombination and Synergize with Olaparib in Pancreatic Cancer Cells 146
BACE-1 Inhibitors: From Recent Single-Target Molecules to Multitarget Compounds for Alzheimer's Disease 139
Synthetic Lethality through the Lens of Medicinal Chemistry 139
null 136
AClAP, Autonomous hierarchical agglomerative Cluster Analysis based protocol to partition conformational datasets 131
Antiproliferative agents that interfere with the cell cycle at the G(1)-->S transition: further development and characterization of a small library of stilbene-derived compounds 129
Alpha7 nicotinic acetylcholine receptor agonists: prediction of their binding affinity through a molecular mechanics Poisson-Boltzmann surface area approach 128
Computational approaches to the study of dual-site and peripheral site binding ache inhibitors 127
Versatility of the Curcumin Scaffold: Discovery of Potent and Balanced Dual BACE-1 and GSK-3β Inhibitors 127
Polyamine conjugation of curcumin analogues toward the discovery of mitochondria-directed neuroprotective agents. 126
Design, synthesis, and biological evaluation of conformationally restricted rivastigmine analogues 125
Benzophenone-based derivatives: A novel series of potent and selective dual inhibitors of acetylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation 125
AN INNOVATIVE PROTOCOL FOR COMPARING PROTEIN BINDING SITES VIA ATOMIC GRID MAPS 125
Dynamic Docking: A Paradigm Shift in Computational Drug Discovery 125
Protein Tunnels: The Case of Urease Accessory Proteins 124
null 123
Analogues of the dual acetylcholinesterase inhibitor AP2238: synthesis and SAR 121
A comparative study on the application of hierarchical-agglomerative clustering approaches to organize outputs of reiterated docking runs. 121
Application of Conformational Clustering in Protein–Ligand Docking 121
null 121
Role of Molecular Dynamics and Related Methods in Drug Discovery 120
A Computational Study of the Binding of Propidium to the Peripheral Anionic Site of Human Acetylcholinesterase 119
Parallel Synthesis, Evaluation, and Preliminary Structure-Activity Relationship of 2,5-Diamino-1,4-benzoquinones as a Novel Class of Bivalent Anti-Prion Compound. 118
null 118
Combining Dyad Protonation and Active Site Plasticity in BACE-1 Structure-Based Drug Design 117
Binding Residence Time through Scaled Molecular Dynamics: A Prospective Application to hDAAO Inhibitors 117
A theoretical investigation of the (0001) covellite surfaces. 114
Collecting and assessing human lactate dehydrogenase-A conformations for structure-based virtual screening 112
Complementary medicinal chemistry-driven strategies toward new antitrypanosomal and antileishmanial lead drug candidates 112
Assessment of capillary volumetric blood microsampling for the analysis of central nervous system drugs and metabolites 112
Density Functional Studies on the Nazarov Reaction Involving Cyclic Systems. 110
Extensive SAR and computational studies of 3-{4-[(benzylmethylamino)methyl]phenyl}-6,7-dimethoxy-2H-2-chromenone (AP2238) derivatives. 110
Covalent Inhibitors of Fatty Acid Amide Hydrolase: A Rationale for the Activity of Piperidine and Piperazine Aryl Ureas 110
Systematic Exploitation of Multiple Receptor Conformations for Virtual Ligand Screening 109
Fluorinated benzophenone derivatives: balanced multipotent agents for Alzheimer's disease 107
Role of phosphorylated Thr160 for the activation of the CDK2/Cyclin A complex 106
Multitargeted drugs for the treatment of Alzheimer's disease 106
A Binding Site for Nonsteroidal Anti-inflammatory Drugs in Fatty Acid Amide Hydrolase 106
Synthetic Lethality Triggered by Combining Olaparib with BRCA2-Rad51 Disruptors 106
Enantioselective nonsteroidal aromatase inhibitors identified through a multidisciplinary medicinal chemistry approach 105
Memoquin: a multi-target-directed ligand as an innovative therapeutic opportunity for Alzheimer's disease 105
Bivalent tacrine-based acetylcholinesterase inhibitors: role of the spacer in the recognition process of the enzyme gorge 104
Multi-Target-Directed Drug Design Strategy: From a Dual Binding Site Acetylcholinesterase Inhibitor to a Trifunctional Compound against Alzheimer's Disease 104
Hybrid Lipoic Acid Derivatives to Attack Prion Disease on Multiple Fronts 104
Toward a rational design of multitarget-directed antioxidants: merging memoquin and lipoic acid molecular frameworks 103
Curcumin analogs as multi-target antioxidants: focus on mitochondria. 103
Multitarget Drug Discovery and Polypharmacology 103
Low molecular weight, non-peptidic agonists of TrkA receptor with NGF-mimetic activity 103
Lead optimization providing a series of flavone derivatives as potent nonsteroidal inhibitors of the cytochrome P450 aromatase enzyme 102
An Advanced Multiple Receptor Conformations Virtual Ligand Screening Protocol for the Identification of Novel BACE-1 Inhibitors 102
In silico modelling--pharmacophores and hERG channel models 101
Computational study of the phosphoryl transfer catalyzed by a cyclin-dependent kinase 101
Allosteric Modulation of Alpha7 Nicotinic Receptors: Mechanistic Insight through Metadynamics and Essential Dynamics 101
Exploring complex protein-ligand recognition mechanisms with coarse metadynamics 101
Monolithic stationary phase coupled with coulometric detection: development of an ion-pair HPLC method for the analysis of quinone-bearing compounds. 100
null 100
Target-related applications of first principles quantum chemical methods in drug design 99
Heterocyclic inhibitors of AChE acylation and peripheral sites. 99
Combining galantamine and memantine in multitargeted, new chemical entities potentially useful in Alzheimer's disease. 98
Discovery of Multitarget Agents Active as Broad-Spectrum Antivirals and Correctors of Cystic Fibrosis Transmembrane Conductance Regulator for Associated Pulmonary Diseases 98
BiKi Life Sciences: A New Suite for Molecular Dynamics and Related Methods in Drug Discovery 98
Docking ligands on protein surfaces: the case study of prion protein. 97
Neglected tropical diseases: multi-target-directed ligands in the search for novel lead candidates against Trypanosoma and Leishmania 97
Targeting Alzheimer’s disease: Novel indanone hybrids bearing a pharmacophoric fragment of AP2238 97
Kinetics of protein-ligand unbinding via smoothed potential molecular dynamics simulations 97
Whole blood and oral fluid microsampling for the monitoring of patients under treatment with antidepressant drugs 97
Novel Class of Quinone-Bearing Polyamines as Multi-Target-Directed Ligands To Combat Alzheimer's Disease 97
Modeling the hERG potassium channel in a phospholipid bilayer: Molecular dynamics and drug docking studies 97
Multi-target-Directed Ligands To Combat Neurodegenerative Diseases 96
In silico antitarget screening 96
Investigating Drug-Target Residence Time in Kinases through Enhanced Sampling Simulations 96
Dual target compounds for the treatment of Alzheimer’s disease. 95
null 95
Navigating the Chemical Space of Multitarget-Directed Ligands: From Hybrids to Fragments in Alzheimer's Disease 95
Design, synthesis, and evaluation of benzophenone derivatives as novel acetylcholinesterase inhibitors 94
Privileged structure-guided synthesis of quinazoline derivatives as inhibitors of trypanothione reductase 94
In vivo characterization of ARN14140, a memantine/galantamine-based multi-target compound for Alzheimer's disease 94
Imidazolylmethylbenzophenones as highly potent aromatase inhibitors. 93
The role of Li(+), Na(+), and K(+) in the ligand binding inside the human acetylcholinesterase gorge 93
Synthesis of Monomeric Derivatives To Probe Memoquin's Bivalent Interactions 93
Mapping cholesterol interaction sites on serotonin transporter through coarse-grained molecular dynamics 93
Structure-Activity Relationships and Binding Mode in the Human Acetylcholinesterase Active Site of Pseudo-Irreversible Inhibitors Related to Xanthostigmine 92
Organocatalytic Asymmetric Conjugate Addition of 1,3-Dicarbonyl Compounds to Maleimides 92
Multitarget Ligands in the Search for Novel Lead Candidates against Trypanosoma and Leishmania 91
null 91
Kernel-Based, Partial Least Squares Quantitative Structure-Retention Relationship Model for UPLC Retention Time Prediction: A Useful Tool for Metabolite Identification 91
Pharmacological Inhibition of the Ubiquitin Ligase RNF5 Rescues F508del-CFTR in Cystic Fibrosis Airway Epithelia 91
Characterization of Cholinesterase inhibitors by means of immobilized enzyme reactor 90
Totale 11474
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Categoria #
all - tutte 37213
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 37213
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2017/2018525 0000 00 00 1051212
2018/20191940 8123624272 36215 12187 168308172220
2019/20207722 1148188120459 758761 9741076 1011543230454
2020/20214800 842354173208 204497 90294 3762592591244
2021/20225044 587151351271 486354 147420 286264799928
2022/20234479 561774280618 418335 208335 950000
Totale 24674