CRIS Current Research Information System

CAVALLI, ANDREA
 Distribuzione geografica
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Continente #
NA - Nord America 16.999
AS - Asia 15.924
EU - Europa 12.584
SA - Sud America 3.412
AF - Africa 1.877
OC - Oceania 43
Continente sconosciuto - Info sul continente non disponibili 22
Totale 50.861
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Nazione #
US - Stati Uniti d'America 16.461
CN - Cina 4.422
SG - Singapore 4.010
GB - Regno Unito 2.970
IT - Italia 2.869
VN - Vietnam 2.381
BR - Brasile 2.317
DE - Germania 1.634
IN - India 1.099
HK - Hong Kong 994
SE - Svezia 906
UA - Ucraina 803
RU - Federazione Russa 793
FR - Francia 681
VE - Venezuela 508
KR - Corea 473
ZA - Sudafrica 450
IE - Irlanda 448
IQ - Iraq 438
SA - Arabia Saudita 390
CI - Costa d'Avorio 340
MA - Marocco 334
IL - Israele 321
MX - Messico 273
AR - Argentina 256
NL - Olanda 243
JP - Giappone 241
TG - Togo 225
KZ - Kazakistan 212
EE - Estonia 206
JO - Giordania 150
CA - Canada 130
TN - Tunisia 125
FI - Finlandia 118
ES - Italia 114
CH - Svizzera 112
PK - Pakistan 106
HR - Croazia 105
AT - Austria 100
AE - Emirati Arabi Uniti 96
SC - Seychelles 94
BG - Bulgaria 83
ID - Indonesia 74
EG - Egitto 73
EC - Ecuador 71
DZ - Algeria 70
CO - Colombia 67
PL - Polonia 66
CL - Cile 64
BD - Bangladesh 63
IR - Iran 57
TR - Turchia 57
PH - Filippine 56
BE - Belgio 53
CZ - Repubblica Ceca 49
GR - Grecia 49
NG - Nigeria 49
PY - Paraguay 41
TW - Taiwan 41
AU - Australia 40
RO - Romania 35
UY - Uruguay 35
OM - Oman 34
UZ - Uzbekistan 33
NP - Nepal 30
PE - Perù 30
LB - Libano 28
SN - Senegal 27
KE - Kenya 26
DO - Repubblica Dominicana 24
PA - Panama 22
MD - Moldavia 21
BO - Bolivia 20
CR - Costa Rica 20
AZ - Azerbaigian 19
GA - Gabon 19
AO - Angola 18
EU - Europa 17
GT - Guatemala 17
LT - Lituania 16
MY - Malesia 15
HN - Honduras 14
PT - Portogallo 14
HU - Ungheria 12
LV - Lettonia 12
PS - Palestinian Territory 12
SK - Slovacchia (Repubblica Slovacca) 12
DK - Danimarca 10
NO - Norvegia 10
RS - Serbia 10
AM - Armenia 9
BZ - Belize 9
CG - Congo 9
JM - Giamaica 9
SY - Repubblica araba siriana 9
TH - Thailandia 9
GE - Georgia 8
SV - El Salvador 8
AL - Albania 7
BY - Bielorussia 7
Totale 50.767
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Città #
Singapore 2.591
Southend 2.493
Fairfield 1.947
Ashburn 1.545
Chandler 983
Hong Kong 947
Woodbridge 946
Hefei 941
Seattle 880
Wilmington 871
Houston 817
Santa Clara 802
Bologna 779
Ann Arbor 744
Dong Ket 718
Cambridge 667
Princeton 630
Beijing 498
Jacksonville 491
Dublin 443
Boardman 416
Ho Chi Minh City 416
Seoul 411
Hanoi 353
Abidjan 338
Nanjing 271
Westminster 261
Padova 245
Lomé 225
Los Angeles 222
Berlin 210
Tokyo 209
Milan 198
São Paulo 164
Tel Aviv 159
Buffalo 152
Amman 149
Jeddah 145
Jinan 137
Baghdad 136
Saint Petersburg 133
New York 131
Bengaluru 125
Dallas 121
San Diego 118
Frankfurt am Main 116
Redondo Beach 116
Shenyang 115
Riyadh 114
Redmond 111
Maracaibo 103
Caracas 101
Johannesburg 100
Casablanca 98
Erbil 94
Mülheim 93
Hebei 92
Nanchang 89
Tianjin 86
Changsha 84
Medford 84
Guangzhou 82
Helsinki 74
Falls Church 71
Munich 70
Shanghai 70
Sofia 70
Rio de Janeiro 67
Almaty 65
Cape Town 63
Des Moines 61
Chicago 60
Rome 60
Verona 60
Turin 59
Zhengzhou 57
Dammam 56
Belo Horizonte 55
Haiphong 55
Barcelona 52
Dearborn 52
Norwalk 51
Tunis 51
Vienna 51
Mahé 50
Paris 48
Falkenstein 47
Brussels 46
Stockholm 46
Brasília 45
Medina 45
Abeokuta 44
Amsterdam 44
Genoa 43
Phoenix 43
Bern 41
Nuremberg 41
Olalla 41
Pune 41
Council Bluffs 40
Totale 29.891
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Nome #
Watching the release of a photopharmacological drug from tubulin using time-resolved serial crystallography 6.920
A small molecule targeting the multifactorial nature of Alzheimer's disease 465
3,4-Dihydro-1,3,5-triazin-2(1H)-ones as the First Dual BACE-1/GSK-3β Fragment Hits against Alzheimer's Disease 376
A RAD51/BRCA2 small molecule inhibitor enhances the antineoplastic effect of the PARPi talazoparib in pancreatic cancer 316
The 1,2,4-Triazolo[4,3-a]pyrazin-3-one as a Versatile Scaffold for the Design of Potent Adenosine Human Receptor Antagonists. Structural Investigations to Target the A2AReceptor Subtype 300
La metadinamica nello studio dell'energia libera di complessi recettoriali binari 263
A small chemical library of 2-aminoimidazole derivatives as BACE-1 inhibitors: structure-based design, synthesis, and biological evaluation 238
Rad51/Brca2 Disruptors Inhibit Homologous Recombination and Synergize with Olaparib in Pancreatic Cancer Cells 238
Synthetic Lethality in Pancreatic Cancer: Discovery of a New RAD51-BRCA2 Small Molecule Disruptor That Inhibits Homologous Recombination and Synergizes with Olaparib 236
Cholinesterase inhibitors: xanthostigmine derivatives blocking the acetylcholinesterase-induced beta-amyloid aggregation. 235
Multitarget Strategy to Address Alzheimer's Disease: Design, Synthesis, Biological Evaluation, and Computational Studies of Coumarin-Based Derivatives 231
A journey through targeting BRCA2-RAD51 protein-protein interaction to establish synthetic lethality as paradigm for anticancer drug discovery 227
Role of Molecular Dynamics and Related Methods in Drug Discovery 227
Insights into the activity of ARN24089, a new RAD51-BRCA2 disruptor that inhibits homologous recombination and achieves synthetic lethality in pancreatic cancer 224
Structure-Activity Relationships and Binding Mode in the Human Acetylcholinesterase Active Site of Pseudo-Irreversible Inhibitors Related to Xanthostigmine 223
An automated docking protocol for HERG channel blockers. 221
A molecular dynamics study of reovirus attachment protein sigma1 reveals conformational changes in sigma1 structure 214
A Catalytic Mechanism for Cysteine N-Terminal Nucleophile Hydrolases, as Revealed by Free Energy Simulations 214
Computational design and discovery of "minimally structured" hERG blockers. 211
The mechanistic understanding of the BRCA2-RAD51 interaction: an integrated structural biophysics study 208
2-Phenoxy-1,4-naphthoquinones: From a Multitarget Antitrypanosomal to a Potential Antitumor Profile 206
Analogues of the dual acetylcholinesterase inhibitor AP2238: synthesis and SAR 194
Design, synthesis, and biological evaluation of conformationally restricted rivastigmine analogues 193
Assessment of capillary volumetric blood microsampling for the analysis of central nervous system drugs and metabolites 193
Dynamic Docking: A Paradigm Shift in Computational Drug Discovery 189
Antiproliferative agents that interfere with the cell cycle at the G(1)-->S transition: further development and characterization of a small library of stilbene-derived compounds 188
Protein Tunnels: The Case of Urease Accessory Proteins 188
Curcumin analogs as multi-target antioxidants: focus on mitochondria. 185
Whole blood and oral fluid microsampling for the monitoring of patients under treatment with antidepressant drugs 185
Versatility of the Curcumin Scaffold: Discovery of Potent and Balanced Dual BACE-1 and GSK-3β Inhibitors 183
New Horizons of Synthetic Lethality in Cancer: Current Development and Future Perspectives 182
Computational drug discovery under RNA times 182
Benzophenone-based derivatives: A novel series of potent and selective dual inhibitors of acetylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation 182
Identification and subsequent development of RAD51-BRCA2 disruptors through a fragment-based approach 181
Computational approaches to the study of dual-site and peripheral site binding ache inhibitors 180
SAR and binding mode at the h-AChE active site of pseudo-irreversible inhibitors related to Xanthostigmine 180
Extensive SAR and computational studies of 3-{4-[(benzylmethylamino)methyl]phenyl}-6,7-dimethoxy-2H-2-chromenone (AP2238) derivatives. 179
Polyamine conjugation of curcumin analogues toward the discovery of mitochondria-directed neuroprotective agents. 179
Dissecting the BRCA2 - RAD51 interaction by integrating computational and experimental biophysics 176
Progettazione e sintesi di derivati poliamminici per il trattamento della malattia di Alzheimer 175
BACE-1 Inhibitors: From Recent Single-Target Molecules to Multitarget Compounds for Alzheimer's Disease 174
AClAP, Autonomous hierarchical agglomerative Cluster Analysis based protocol to partition conformational datasets 174
An 19F NMR fragment-based approach for the discovery and development of BRCA2-RAD51 inhibitors to pursuit synthetic lethality in combination with PARP inhibition in pancreatic cancer 173
Collecting and assessing human lactate dehydrogenase-A conformations for structure-based virtual screening 172
A Triazolotriazine-Based Dual GSK-3β/CK-1δ Ligand as a Potential Neuroprotective Agent Presenting Two Different Mechanisms of Enzymatic Inhibition 172
Synthetic Lethality through the Lens of Medicinal Chemistry 169
Synthetic Lethality Triggered by Combining Olaparib with BRCA2-Rad51 Disruptors 167
Lactate dehydrogenase inhibition affects homologous recombination repair independently of cell metabolic asset; implications for anticancer treatment 167
Alpha7 nicotinic acetylcholine receptor agonists: prediction of their binding affinity through a molecular mechanics Poisson-Boltzmann surface area approach 166
Probabilistic Pocket Druggability Prediction via One-Class Learning 165
Density functional study of the enzymatic reaction catalyzed by a cyclin-dependent kinase 162
Enantioselective nonsteroidal aromatase inhibitors identified through a multidisciplinary medicinal chemistry approach 162
Bivalent tacrine-based acetylcholinesterase inhibitors: role of the spacer in the recognition process of the enzyme gorge 162
Parallel Synthesis, Evaluation, and Preliminary Structure-Activity Relationship of 2,5-Diamino-1,4-benzoquinones as a Novel Class of Bivalent Anti-Prion Compound. 162
AN INNOVATIVE PROTOCOL FOR COMPARING PROTEIN BINDING SITES VIA ATOMIC GRID MAPS 162
A comparative study on the application of hierarchical-agglomerative clustering approaches to organize outputs of reiterated docking runs. 162
Binding Residence Time through Scaled Molecular Dynamics: A Prospective Application to hDAAO Inhibitors 162
Elucidating the BRCA2-RAD51 interaction through an integrated structural biophysics approach 161
Density Functional Studies on the Nazarov Reaction Involving Cyclic Systems. 161
Application of Conformational Clustering in Protein–Ligand Docking 161
Complementary medicinal chemistry-driven strategies toward new antitrypanosomal and antileishmanial lead drug candidates 161
Role of phosphorylated Thr160 for the activation of the CDK2/Cyclin A complex 160
Combining Dyad Protonation and Active Site Plasticity in BACE-1 Structure-Based Drug Design 160
In silico modelling--pharmacophores and hERG channel models 158
A Computational Study of the Binding of Propidium to the Peripheral Anionic Site of Human Acetylcholinesterase 157
Toward a rational design of multitarget-directed antioxidants: merging memoquin and lipoic acid molecular frameworks 155
Galantamine-memantine hybrids for Alzheimer's disease: The influence of linker rigidity in biological activity and pharmacokinetic properties 154
Hybrid Lipoic Acid Derivatives to Attack Prion Disease on Multiple Fronts 154
Target-related applications of first principles quantum chemical methods in drug design 153
Multi-Target-Directed Drug Design Strategy: From a Dual Binding Site Acetylcholinesterase Inhibitor to a Trifunctional Compound against Alzheimer's Disease 153
Influence of the Ion Coordination Number on Cation Exchange Reactions with Copper Telluride Nanocrystals 153
BiKi Life Sciences: A New Suite for Molecular Dynamics and Related Methods in Drug Discovery 153
Covalent Inhibitors of Fatty Acid Amide Hydrolase: A Rationale for the Activity of Piperidine and Piperazine Aryl Ureas 152
Elucidating the BRCA2-RAD51 interaction through an integrated biophysical and structural biology approach 150
In vivo characterization of ARN14140, a memantine/galantamine-based multi-target compound for Alzheimer's disease 149
Lead optimization providing a series of flavone derivatives as potent nonsteroidal inhibitors of the cytochrome P450 aromatase enzyme 148
Mapping cholesterol interaction sites on serotonin transporter through coarse-grained molecular dynamics 148
Pharmacological Inhibition of the Ubiquitin Ligase RNF5 Rescues F508del-CFTR in Cystic Fibrosis Airway Epithelia 148
Computational study of the phosphoryl transfer catalyzed by a cyclin-dependent kinase 147
Searching for New Microbiome-Targeted Therapeutics through a Drug Repurposing Approach 147
Multitargeted drugs for the treatment of Alzheimer's disease 146
Fluorinated benzophenone derivatives: balanced multipotent agents for Alzheimer's disease 146
Navigating the Chemical Space of Multitarget-Directed Ligands: From Hybrids to Fragments in Alzheimer's Disease 146
Blood microsampling for untargeted lipidomics 146
Targeting the JAK/STAT Pathway: A Combined Ligand- And Target-Based Approach 146
The role of the peripheral anionic site and cation-pi interactions in the ligand penetration of the human AChE gorge. 145
Derivati a struttura benzofenonica come inibitori dell'acetilcolinesterasi 145
Systematic Exploitation of Multiple Receptor Conformations for Virtual Ligand Screening 144
Targeting Alzheimer’s disease: Novel indanone hybrids bearing a pharmacophoric fragment of AP2238 144
Investigating Drug-Target Residence Time in Kinases through Enhanced Sampling Simulations 144
Enhanced Molecular Dynamics Simulations of Intrinsically Disordered Proteins 144
Nonsteroidal Aromatase inhibitors: synthesis and evaluation of new flavone derivatives 143
Kernel-Based, Partial Least Squares Quantitative Structure-Retention Relationship Model for UPLC Retention Time Prediction: A Useful Tool for Metabolite Identification 143
Discovery of Multitarget Agents Active as Broad-Spectrum Antivirals and Correctors of Cystic Fibrosis Transmembrane Conductance Regulator for Associated Pulmonary Diseases 143
An integrative structural study of RAD52, an emerging target in anticancer drug discovery 142
Design, synthesis, and evaluation of benzophenone derivatives as novel acetylcholinesterase inhibitors 142
Organocatalytic Asymmetric Conjugate Addition of 1,3-Dicarbonyl Compounds to Maleimides 141
Novel Class of Quinone-Bearing Polyamines as Multi-Target-Directed Ligands To Combat Alzheimer's Disease 141
Memoquin: a multi-target-directed ligand as an innovative therapeutic opportunity for Alzheimer's disease 140
Low molecular weight, non-peptidic agonists of TrkA receptor with NGF-mimetic activity 140
Totale 24.734
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Categoria #
all - tutte 130.173
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 130.173
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20213.019 0 0 0 0 0 497 90 294 376 259 259 1.244
2021/20225.060 587 151 355 274 488 354 147 421 286 264 802 931
2022/20235.273 562 775 280 619 420 335 183 318 914 205 377 285
2023/20242.229 164 298 138 179 217 317 163 164 75 159 182 173
2024/20257.653 313 1.135 733 438 1.306 404 559 297 249 363 409 1.447
2025/202616.324 2.113 3.019 2.370 3.826 4.175 821 0 0 0 0 0 0
Totale 51.690