CRIS Current Research Information System

CAVALLI, ANDREA
 Distribuzione geografica
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Continente #
AS - Asia 21.079
NA - Nord America 18.704
EU - Europa 13.783
SA - Sud America 3.989
AF - Africa 2.106
OC - Oceania 59
Continente sconosciuto - Info sul continente non disponibili 22
Totale 59.742
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Nazione #
US - Stati Uniti d'America 18.079
CN - Cina 5.210
SG - Singapore 4.853
VN - Vietnam 4.341
IT - Italia 3.168
GB - Regno Unito 3.032
BR - Brasile 2.690
DE - Germania 1.703
IN - India 1.301
HK - Hong Kong 1.138
FR - Francia 1.101
SE - Svezia 918
UA - Ucraina 816
RU - Federazione Russa 815
VE - Venezuela 606
IL - Israele 533
IQ - Iraq 520
KR - Corea 516
ZA - Sudafrica 514
SA - Arabia Saudita 507
IE - Irlanda 454
JP - Giappone 398
MA - Marocco 392
CI - Costa d'Avorio 347
KZ - Kazakistan 328
MX - Messico 307
AR - Argentina 288
NL - Olanda 270
FI - Finlandia 231
TG - Togo 225
EE - Estonia 207
JO - Giordania 166
CA - Canada 158
PK - Pakistan 156
PH - Filippine 149
TN - Tunisia 147
ES - Italia 138
AE - Emirati Arabi Uniti 135
BD - Bangladesh 125
AT - Austria 123
CH - Svizzera 116
HR - Croazia 109
SC - Seychelles 95
TR - Turchia 92
EG - Egitto 91
ID - Indonesia 87
CO - Colombia 86
CL - Cile 85
DZ - Algeria 85
TW - Taiwan 85
BG - Bulgaria 84
EC - Ecuador 84
PL - Polonia 84
TH - Thailandia 68
IR - Iran 59
BE - Belgio 56
AU - Australia 53
GR - Grecia 52
NG - Nigeria 51
CZ - Repubblica Ceca 49
OM - Oman 48
PY - Paraguay 46
UZ - Uzbekistan 46
RO - Romania 41
DK - Danimarca 40
UY - Uruguay 39
LB - Libano 37
NP - Nepal 37
PE - Perù 37
KE - Kenya 36
SN - Senegal 34
PA - Panama 27
CR - Costa Rica 26
MD - Moldavia 26
MY - Malesia 26
DO - Repubblica Dominicana 25
AZ - Azerbaigian 24
BO - Bolivia 24
GA - Gabon 23
LT - Lituania 21
GT - Guatemala 19
HN - Honduras 19
PS - Palestinian Territory 19
AO - Angola 18
ET - Etiopia 18
PT - Portogallo 18
EU - Europa 17
BY - Bielorussia 16
HU - Ungheria 16
LV - Lettonia 13
SK - Slovacchia (Repubblica Slovacca) 13
SY - Repubblica araba siriana 12
CG - Congo 11
JM - Giamaica 11
RS - Serbia 11
AM - Armenia 10
NO - Norvegia 10
BZ - Belize 9
GE - Georgia 9
SV - El Salvador 9
Totale 59.617
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Città #
Singapore 3.373
Southend 2.493
Fairfield 1.947
Ashburn 1.688
Hong Kong 1.044
Chandler 983
Hefei 948
Woodbridge 946
Ho Chi Minh City 924
Seattle 880
San Jose 872
Wilmington 871
Bologna 836
Houston 823
Santa Clara 823
Hanoi 814
Ann Arbor 744
Dong Ket 718
Cambridge 667
Princeton 630
Beijing 521
Jacksonville 492
Dublin 449
Boardman 424
Seoul 414
Lauterbourg 362
Abidjan 344
Tokyo 321
Nanjing 282
Westminster 261
Los Angeles 251
Padova 245
Lomé 225
Tel Aviv 220
Berlin 211
Milan 210
São Paulo 197
Jeddah 190
Helsinki 182
New York 168
Amman 164
Baghdad 163
Frankfurt am Main 162
Buffalo 158
Riyadh 152
Council Bluffs 148
Jinan 140
Saint Petersburg 133
Bengaluru 130
Johannesburg 129
Dallas 126
Haiphong 126
Caracas 125
Da Nang 121
Shenyang 119
San Diego 118
Casablanca 116
Redondo Beach 116
Maracaibo 114
Guangzhou 113
Redmond 111
Almaty 109
Erbil 105
Shanghai 100
Changsha 98
Tianjin 94
Mülheim 93
Hebei 92
Nanchang 92
Medford 84
Cape Town 77
Chicago 71
Falls Church 71
Munich 71
Rome 71
Rio de Janeiro 70
Sofia 70
Dammam 69
Turin 66
Vienna 66
Des Moines 63
Tunis 63
Zhengzhou 61
Belo Horizonte 60
Verona 60
Amsterdam 58
Florence 58
Paris 56
Medina 55
Genoa 54
Biên Hòa 53
Barcelona 52
Dearborn 52
Astana 51
Norwalk 51
Agrolândia 50
London 50
Mahé 50
Modena 50
Stockholm 50
Totale 34.443
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Nome #
Watching the release of a photopharmacological drug from tubulin using time-resolved serial crystallography 8.404
A small molecule targeting the multifactorial nature of Alzheimer's disease 511
3,4-Dihydro-1,3,5-triazin-2(1H)-ones as the First Dual BACE-1/GSK-3β Fragment Hits against Alzheimer's Disease 423
Role of Molecular Dynamics and Related Methods in Drug Discovery 347
A RAD51/BRCA2 small molecule inhibitor enhances the antineoplastic effect of the PARPi talazoparib in pancreatic cancer 346
The 1,2,4-Triazolo[4,3-a]pyrazin-3-one as a Versatile Scaffold for the Design of Potent Adenosine Human Receptor Antagonists. Structural Investigations to Target the A2AReceptor Subtype 318
2-Phenoxy-1,4-naphthoquinones: From a Multitarget Antitrypanosomal to a Potential Antitumor Profile 309
Multitarget Strategy to Address Alzheimer's Disease: Design, Synthesis, Biological Evaluation, and Computational Studies of Coumarin-Based Derivatives 287
La metadinamica nello studio dell'energia libera di complessi recettoriali binari 275
Rad51/Brca2 Disruptors Inhibit Homologous Recombination and Synergize with Olaparib in Pancreatic Cancer Cells 275
Synthetic Lethality in Pancreatic Cancer: Discovery of a New RAD51-BRCA2 Small Molecule Disruptor That Inhibits Homologous Recombination and Synergizes with Olaparib 270
The mechanistic understanding of the BRCA2-RAD51 interaction: an integrated structural biophysics study 260
A journey through targeting BRCA2-RAD51 protein-protein interaction to establish synthetic lethality as paradigm for anticancer drug discovery 259
Galantamine-memantine hybrids for Alzheimer's disease: The influence of linker rigidity in biological activity and pharmacokinetic properties 256
A small chemical library of 2-aminoimidazole derivatives as BACE-1 inhibitors: structure-based design, synthesis, and biological evaluation 255
An automated docking protocol for HERG channel blockers. 255
Insights into the activity of ARN24089, a new RAD51-BRCA2 disruptor that inhibits homologous recombination and achieves synthetic lethality in pancreatic cancer 250
Cholinesterase inhibitors: xanthostigmine derivatives blocking the acetylcholinesterase-induced beta-amyloid aggregation. 250
Structure-Activity Relationships and Binding Mode in the Human Acetylcholinesterase Active Site of Pseudo-Irreversible Inhibitors Related to Xanthostigmine 244
Computational design and discovery of "minimally structured" hERG blockers. 232
Whole blood and oral fluid microsampling for the monitoring of patients under treatment with antidepressant drugs 232
Dynamic Docking: A Paradigm Shift in Computational Drug Discovery 229
A Catalytic Mechanism for Cysteine N-Terminal Nucleophile Hydrolases, as Revealed by Free Energy Simulations 228
New Horizons of Synthetic Lethality in Cancer: Current Development and Future Perspectives 224
Investigating synthetic lethality and PARP inhibitor resistance in pancreatic cancer through enantiomer differential activity 224
A molecular dynamics study of reovirus attachment protein sigma1 reveals conformational changes in sigma1 structure 221
Assessment of capillary volumetric blood microsampling for the analysis of central nervous system drugs and metabolites 221
Protein Tunnels: The Case of Urease Accessory Proteins 218
Analogues of the dual acetylcholinesterase inhibitor AP2238: synthesis and SAR 216
Versatility of the Curcumin Scaffold: Discovery of Potent and Balanced Dual BACE-1 and GSK-3β Inhibitors 214
Computational drug discovery under RNA times 210
Lactate dehydrogenase inhibition affects homologous recombination repair independently of cell metabolic asset; implications for anticancer treatment 210
Curcumin analogs as multi-target antioxidants: focus on mitochondria. 207
Identification and subsequent development of RAD51-BRCA2 disruptors through a fragment-based approach 205
Polyamine conjugation of curcumin analogues toward the discovery of mitochondria-directed neuroprotective agents. 203
Dissecting the BRCA2 - RAD51 interaction by integrating computational and experimental biophysics 202
New-generation, non-SSRI antidepressants: Drug-drug interactions and therapeutic drug monitoring. Part 2: NaSSAs, NRIs, SNDRIs, MASSAs, NDRIs, and others 200
An 19F NMR fragment-based approach for the discovery and development of BRCA2-RAD51 inhibitors to pursuit synthetic lethality in combination with PARP inhibition in pancreatic cancer 199
Design, synthesis, and biological evaluation of conformationally restricted rivastigmine analogues 199
SAR and binding mode at the h-AChE active site of pseudo-irreversible inhibitors related to Xanthostigmine 199
Antiproliferative agents that interfere with the cell cycle at the G(1)-->S transition: further development and characterization of a small library of stilbene-derived compounds 198
Extensive SAR and computational studies of 3-{4-[(benzylmethylamino)methyl]phenyl}-6,7-dimethoxy-2H-2-chromenone (AP2238) derivatives. 197
Computational approaches to the study of dual-site and peripheral site binding ache inhibitors 196
Benzophenone-based derivatives: A novel series of potent and selective dual inhibitors of acetylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation 196
Probabilistic Pocket Druggability Prediction via One-Class Learning 194
Progettazione e sintesi di derivati poliamminici per il trattamento della malattia di Alzheimer 193
Synthetic Lethality Triggered by Combining Olaparib with BRCA2-Rad51 Disruptors 193
AClAP, Autonomous hierarchical agglomerative Cluster Analysis based protocol to partition conformational datasets 192
Elucidating the BRCA2-RAD51 interaction through an integrated biophysical and structural biology approach 191
Binding Residence Time through Scaled Molecular Dynamics: A Prospective Application to hDAAO Inhibitors 191
An integrative structural study of RAD52, an emerging target in anticancer drug discovery 190
A comparative study on the application of hierarchical-agglomerative clustering approaches to organize outputs of reiterated docking runs. 189
BACE-1 Inhibitors: From Recent Single-Target Molecules to Multitarget Compounds for Alzheimer's Disease 189
Elucidating the BRCA2-RAD51 interaction through an integrated structural biophysics approach 188
Preomic profile of BxPC-3 cells after treatment with BRC4 188
A Triazolotriazine-Based Dual GSK-3β/CK-1δ Ligand as a Potential Neuroprotective Agent Presenting Two Different Mechanisms of Enzymatic Inhibition 188
Differential enantiomers activity of ARN24089 to achieve synthetic lethality in pancreatic cancer 187
Collecting and assessing human lactate dehydrogenase-A conformations for structure-based virtual screening 186
Complementary medicinal chemistry-driven strategies toward new antitrypanosomal and antileishmanial lead drug candidates 186
Synthetic Lethality through the Lens of Medicinal Chemistry 183
Blood microsampling for untargeted lipidomics 182
In vivo characterization of ARN14140, a memantine/galantamine-based multi-target compound for Alzheimer's disease 182
Density Functional Studies on the Nazarov Reaction Involving Cyclic Systems. 181
Elucidating the BRCA2 - RAD51 interaction by integrating computational and experimental biophysics 180
Role of phosphorylated Thr160 for the activation of the CDK2/Cyclin A complex 180
Enantioselective nonsteroidal aromatase inhibitors identified through a multidisciplinary medicinal chemistry approach 179
Alpha7 nicotinic acetylcholine receptor agonists: prediction of their binding affinity through a molecular mechanics Poisson-Boltzmann surface area approach 179
Design and synthesis of RAD51-BRCA2 protein-protein interaction disruptors to trigger synthetic lethality with Olaparib in pancreatic cancer cells 178
Combining Dyad Protonation and Active Site Plasticity in BACE-1 Structure-Based Drug Design 178
Searching for New Microbiome-Targeted Therapeutics through a Drug Repurposing Approach 176
Mapping cholesterol interaction sites on serotonin transporter through coarse-grained molecular dynamics 175
AN INNOVATIVE PROTOCOL FOR COMPARING PROTEIN BINDING SITES VIA ATOMIC GRID MAPS 174
Targeting the JAK/STAT Pathway: A Combined Ligand- And Target-Based Approach 173
Density functional study of the enzymatic reaction catalyzed by a cyclin-dependent kinase 172
Target-related applications of first principles quantum chemical methods in drug design 172
Bivalent tacrine-based acetylcholinesterase inhibitors: role of the spacer in the recognition process of the enzyme gorge 171
Toward a rational design of multitarget-directed antioxidants: merging memoquin and lipoic acid molecular frameworks 171
Investigating Drug-Target Residence Time in Kinases through Enhanced Sampling Simulations 171
Parallel Synthesis, Evaluation, and Preliminary Structure-Activity Relationship of 2,5-Diamino-1,4-benzoquinones as a Novel Class of Bivalent Anti-Prion Compound. 170
A Computational Study of the Binding of Propidium to the Peripheral Anionic Site of Human Acetylcholinesterase 170
Multi-Target-Directed Drug Design Strategy: From a Dual Binding Site Acetylcholinesterase Inhibitor to a Trifunctional Compound against Alzheimer's Disease 169
Lead optimization providing a series of flavone derivatives as potent nonsteroidal inhibitors of the cytochrome P450 aromatase enzyme 168
The Mechanistic Understanding of RAD51 Defibrillation: A Critical Step in BRCA2-Mediated DNA Repair by Homologous Recombination 167
Influence of the Ion Coordination Number on Cation Exchange Reactions with Copper Telluride Nanocrystals 167
Predicting Residence Time and Drug Unbinding Pathway through Scaled Molecular Dynamics 167
Machine learning for precision diagnostics of autoimmunity 166
In silico modelling--pharmacophores and hERG channel models 166
Nonsteroidal Aromatase inhibitors: synthesis and evaluation of new flavone derivatives 166
Application of Conformational Clustering in Protein–Ligand Docking 166
Exploring Conformational Dynamics of the Extracellular Venus flytrap Domain of the GABAB Receptor: A Path-Metadynamics Study 166
Hybrid Lipoic Acid Derivatives to Attack Prion Disease on Multiple Fronts 165
BiKi Life Sciences: A New Suite for Molecular Dynamics and Related Methods in Drug Discovery 165
Derivati a struttura benzofenonica come inibitori dell'acetilcolinesterasi 164
Multitarget Ligands in the Search for Novel Lead Candidates against Trypanosoma and Leishmania 164
Navigating the Chemical Space of Multitarget-Directed Ligands: From Hybrids to Fragments in Alzheimer's Disease 164
Exploration of Tools for the Interpretation of Human Non-Coding Variants 163
Enhanced Molecular Dynamics Simulations of Intrinsically Disordered Proteins 163
Proteostasis Regulators in Cystic Fibrosis: Current Development and Future Perspectives 163
Dried Volumetric Microsampling Approaches for the Therapeutic Drug Monitoring of Psychiatric Patients Undergoing Clozapine Treatment 162
Fluorinated benzophenone derivatives: balanced multipotent agents for Alzheimer's disease 162
Totale 28.919
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Categoria #
all - tutte 144.583
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 144.583
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20211.762 0 0 0 0 0 0 0 0 0 259 259 1.244
2021/20225.060 587 151 355 274 488 354 147 421 286 264 802 931
2022/20235.273 562 775 280 619 420 335 183 318 914 205 377 285
2023/20242.229 164 298 138 179 217 317 163 164 75 159 182 173
2024/20257.653 313 1.135 733 438 1.306 404 559 297 249 363 409 1.447
2025/202625.313 2.113 3.019 2.370 3.826 4.175 2.513 2.184 999 3.172 942 0 0
Totale 60.679