CRIS Current Research Information System

SIMONETTI, GIORGIA
 Distribuzione geografica
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Continente #
NA - Nord America 5.294
AS - Asia 4.547
EU - Europa 4.206
AF - Africa 350
SA - Sud America 221
OC - Oceania 11
Continente sconosciuto - Info sul continente non disponibili 9
Totale 14.638
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Nazione #
US - Stati Uniti d'America 5.230
VN - Vietnam 1.300
CN - Cina 1.244
SG - Singapore 1.181
GB - Regno Unito 1.122
IT - Italia 703
SE - Svezia 563
DE - Germania 538
HK - Hong Kong 313
IN - India 213
FR - Francia 201
RU - Federazione Russa 199
NL - Olanda 194
BR - Brasile 165
IE - Irlanda 164
TG - Togo 95
KR - Corea 91
ZA - Sudafrica 88
FI - Finlandia 86
UA - Ucraina 82
EE - Estonia 78
CI - Costa d'Avorio 77
BG - Bulgaria 71
NG - Nigeria 60
BE - Belgio 50
CH - Svizzera 48
CA - Canada 42
JO - Giordania 42
JP - Giappone 32
AR - Argentina 25
ID - Indonesia 24
PL - Polonia 24
SC - Seychelles 22
ES - Italia 21
AT - Austria 20
IR - Iran 16
MX - Messico 15
BD - Bangladesh 14
UZ - Uzbekistan 14
GR - Grecia 13
IQ - Iraq 10
AU - Australia 9
EC - Ecuador 9
EU - Europa 9
LT - Lituania 7
PY - Paraguay 7
LB - Libano 6
TR - Turchia 6
MY - Malesia 5
AE - Emirati Arabi Uniti 4
CL - Cile 4
CO - Colombia 4
HR - Croazia 4
MK - Macedonia 4
PK - Pakistan 4
AZ - Azerbaigian 3
EG - Egitto 3
GT - Guatemala 3
LV - Lettonia 3
PE - Perù 3
PH - Filippine 3
RO - Romania 3
TW - Taiwan 3
HU - Ungheria 2
IL - Israele 2
KG - Kirghizistan 2
KZ - Kazakistan 2
MA - Marocco 2
NP - Nepal 2
NZ - Nuova Zelanda 2
PT - Portogallo 2
SA - Arabia Saudita 2
UY - Uruguay 2
AL - Albania 1
AM - Armenia 1
BA - Bosnia-Erzegovina 1
BH - Bahrain 1
CZ - Repubblica Ceca 1
DM - Dominica 1
DO - Repubblica Dominicana 1
DZ - Algeria 1
GE - Georgia 1
GY - Guiana 1
HN - Honduras 1
KE - Kenya 1
KH - Cambogia 1
KW - Kuwait 1
LA - Repubblica Popolare Democratica del Laos 1
LK - Sri Lanka 1
NI - Nicaragua 1
PS - Palestinian Territory 1
SK - Slovacchia (Repubblica Slovacca) 1
TM - Turkmenistan 1
TN - Tunisia 1
VE - Venezuela 1
Totale 14.638
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Città #
Southend 994
Singapore 779
Dong Ket 772
Ashburn 645
Chandler 541
Fairfield 458
Hong Kong 310
Ann Arbor 305
Houston 280
Woodbridge 234
Wilmington 233
Seattle 218
Beijing 209
Hefei 204
Cambridge 187
Bologna 178
Princeton 170
Dublin 163
Boardman 155
Santa Clara 147
Ho Chi Minh City 112
Lomé 95
Seoul 88
Westminster 83
Nanjing 81
New York 80
Padova 79
Los Angeles 78
Abidjan 77
Hanoi 74
Sofia 68
Medford 60
Helsinki 58
Munich 55
Berlin 49
Brussels 49
Abeokuta 46
Dallas 46
Milan 46
Jinan 45
Buffalo 43
Amman 41
Bern 39
Bremen 36
Shenyang 35
Redondo Beach 34
Changsha 33
Redwood City 33
Saint Petersburg 32
Hebei 30
Nanchang 29
Turin 29
Guangzhou 28
Frankfurt am Main 27
Tokyo 27
Falls Church 25
Jiaxing 23
San Diego 23
Florence 22
Turku 20
Bengaluru 19
Jacksonville 19
Paris 19
Toronto 19
Jakarta 18
Hangzhou 17
London 17
Mountain View 17
Shanghai 17
Chicago 14
Ningbo 14
Redmond 14
Taizhou 14
Tianjin 14
Biên Hòa 13
Haikou 13
Vienna 13
Dearborn 12
Düsseldorf 12
Falkenstein 12
Nuremberg 12
São Paulo 12
Amsterdam 11
Da Nang 11
San Francisco 11
Zhengzhou 11
Chennai 10
Phoenix 10
Warsaw 10
Brooklyn 9
Chengdu 9
Haiphong 9
Manchester 9
Norwalk 9
Rome 9
Lanzhou 8
Leawood 8
Orem 8
Romainville 8
Roubaix 8
Totale 9.659
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Nome #
Aneuploid acute myeloid leukemia exhibits a signature of genomic alterations in the cell cycle and protein degradation machinery 332
5′UTR point substitutions and N-terminal truncating mutations of ANKRD26 in acute myeloid leukemia 321
Adult "Triple Negative" ACUTE Lymphoblastic Leukemia Genome Wide Characterization 276
A Specific Pattern of Somatic Mutations Associates with Poor Prognosis Aneuploid Acute Myeloid Leukemia: Results from the European NGS-PTL Consortium 270
Network integration of multi-tumour omics data suggests novel targeting strategies 264
Aggressive Aneuploid Acute Myeloid Leukemia Is Dependent on Alterations of P53, Gain of APC and PLK1 and Loss of RAD50 258
Chromothripsis in acute myeloid leukemia: Biological features and impact on survival 240
Acute myeloid leukemia cell and stem-progenitor cell behavior studied in mimetic bone marrow microenvironment 236
Alterations in phosphatidylinositol 3-phosphate (PI3P) pathway and cAMP pathway confirm poor prognosis and reduced overall survival (OS) in a series of 209 acute myeloid leukemia patients 230
Blinatumomab Is Safe and Effective in Relapsed and MRD Positive B-ALL CD19+ Patients: The Bologna Compassionate Program Experience 220
Alterations in Pathways Regulating Phosphatidil Inositol 3 Phosphate (PI3P) Produce Both Cell Proliferation and Therapy Resistance, and Define a Group of Patients with Poor Prognosis in Acute Myeloid Leukemia (AML) 218
The alteration in key regulator genes of autophagy is mainstream mechanism of therapy resistance and impact prognosis of acute myelogenous leukemia (AML): results from diagnosis genomic analysis on 148 consecutive patients treated with intensive chemotherapy and long-term survival follow-up 214
Alterations of BRCA1 and PALB2 Define a Novel Class of Complex-Karyotype AML with a Very Bad Prognosis 211
Co-occurrence of alterations in the DNA damage repair genes synergize with uncontrolled proliferation and associate with very-poor prognosis in acute myeloid leukemia patients 209
Chromothripsis in Acute Myeloid Leukemia Is Strongly Associated with Poor Prognosis and TP53 Alterations 206
Chromothripsis in AML patients: A new mechanism of cancer initiation and progression 201
A cell cycle-related genomic and transcriptomic signature distinguish aneuploid and euploid acute myeloid leukemia 200
Optimized pipeline of MuTect and GATK tools to improve the detection of somatic single nucleotide polymorphisms in whole-exome sequencing data 195
Epigenetically induced ectopic expression of uncx impairs the proliferation and differentiation of myeloid cells 193
P-206 3D in vitro modelling of relapsed/refractory multiple myeloma to unveil mechanisms of acquired resistance to therapy 185
Clustering Adult ACUTE Lymphoblastic Leukemia (ALL) Philadelphia Negative (Ph-) By Whole Exome Sequencing (WES) Analysis 182
Bromodomain Inhibition Is Effective Against Acute Myeloid Leukemia Cells Under Hypoxia and Induces Genome-Dependent Metabolic Perturbations 177
Fanconi anemia gene variants in therapy-related myeloid neoplasms 177
A novel Rag2-/- c-/--xenograft model of human CLL 176
CIRCULATING CD34+ STEM/PROGENITOR CELLS FROM TRIPLE NEGATIVE PATIENTS WITH MYELOFIBROSIS SHOW DIFFERENT NUMBER, GENE EXPRESSION PROFILE AND IN VITRO RESPONSE TO INFLAMMATORY STIMULI AS COMPARED WITH THE JAK2(V617F) MUTATED COUNTERPARTS 173
Targeting the p53-MDM2 interaction by the small-molecule MDM2 antagonist Nutlin-3a: A new challenged target therapy in adult Philadelphia positive acute lymphoblastic leukemia patients 172
Ex-Vivo Drug Response Profiling for Precision Medicine Approaches in Acute Myeloid Leukemia with the Open Microwell Microfluidic Platform 170
Transcriptional Regulation of Germinal Center B and Plasma Cell Fates by Dynamical Control of IRF4 168
Distinct pattern of alterations in tp53 mutated and wild type acute myeloid leukemia (AML) patients 167
Deficient necroptosis pathway as a negative prognostic factor in acute myeloid leukemia. 167
HS1 has a central role in the trafficking and homing of leukemic B cells 166
Copy number variants signature in two patients with relapsed acute promyelocytic leukemia 166
Novel Genomic Patterns of Metabolic Remodeling in Acute Myeloid Leukemia 163
Impact on survival of catastrophic karyotype events in 101 consecutive acute myeloid leukemia (AML) patients: High risk karyotype and chromothripsis 162
A new biomarker of response to 5-azacitidine therapy in MDS and AML patients: SIRPB1 159
Clec12a: A new AML stem cell-associated antigen 158
SIRPB1 Is a Strong Predictor Biomarker of Response to 5-Azacitidine Therapy in MDS and AML Patients 157
An analysis pipeline for variant discovery in Whole Exome Sequencing data of cancer samples. 155
Emerging Signatures of Hematological Malignancies from Gene Expression and Transcription Factor-Gene Regulations 153
Survival analysis of patients carrying different FLT3 mutations (internal tandem duplication (ITD) and tyrosine kinase domain (TKD) mutations) in 459 consecutive non M3 newly diagnosed acute myeloid leukemia (AML) 153
MHC-I Antigen Presentation Role in Immune Escape of Acute Myeloid Leukemia with High Burden of Genomic Aberration 153
Gemtuzumab-Ozogamicin Containing Regimens As Induction Therapy Give the Highest Complete Remission Rate and the Longest Overall Survival Compared with Other Induction Regimens in Patients with Newly Diagnosed Acute Myeloid Leukemia 153
Very Poor Outcome and Chemoresistance of Acute Myeloid Leukemia Patients with TP53 Mutations: Correlation with Complex Karyotype and Clinical Outcome 152
Dissecting the Molecular Mechanisms of Aneuploidy in Acute Myeloid Leukemia By Next Generation Sequencing 152
Survival and outcome data observed in 98 patients affected by acute myeloid leukemia undergoing chemotherapy consolidation courses treatment followed by autologous bone marrow transplantation (auto-BMT) 150
Microarray analysis to identifiy novel copy number alterations in acute myeloid leukemia 149
Two or More Chemotherapy Consolidation Courses, Followed By Autologous Bone Marrow Transplantation, and MRD Negativity, Give Long Term Overall Survival in Acute Myeloid Leukemia Patients 149
Denatonium as a Bitter Taste Receptor Agonist Modifies Transcriptomic Profile and Functions of Acute Myeloid Leukemia Cells 148
Targeting Macrophages Sensitizes Chronic Lymphocytic Leukemia to Apoptosis and Inhibits Disease Progression 145
Efficacy of Azacitidine in the treatment of adult patients aged 65 years or older with AML 145
RNA Sequencing Reveals Novel and Rare Fusion Transcripts in Acute Myeloid Leukemia 145
CDC20 in and out of mitosis: a prognostic factor and therapeutic target in hematological malignancies 144
Prognostic significance of alterations of pathways regulating autophagy in acute myeloid leukemia 144
A New Entity of Acute Myeloid Leukemia Driven By Epigenetic and Somatic Dis-Regulation of Uncx, a Novel Homeobox Transcription Factor Gene 144
Revealing very small FLT3 ITD mutated clones by ultra-deep sequencing analysis has important clinical implications in AML patients 139
TP53 mutations are mutually exclusive with FLT3 and NPM mutations in AML patients and are strongly associated with complex karyotype and poor outcome 134
Genomic-Wide Analysis By High Resolution SNP Array Identifies Novel Genomic Alteration in Acute Myeloid Leukemia 133
SNP array reveals a new deletion of JAK2 in AML patients 133
Separase overexpression defines a new subset of acute myeloma leukemia patients characterized by high CD34 and MYC levels 132
Exploring the role of PARP1 inhibition in enhancing antibody–drug conjugate therapy for acute leukemias: insights from DNA damage response pathway interactions 131
FOXM1 Transcription Factor Is a Component of Beta Catenin Signaling in Hematopoietic Progenitors of Chronic Myeloid Leukemia 130
Tp53 mutation screening in adult acute myeloid leukemia (AML) patients shows a strong association with complex karyotype and poor outcome 130
Genomic wide microarray analysis identifies novel copy number alterations in adult acute myeloid leukemia 130
The Irf4 Gene, a Susceptibility Locus for Chronic Lymphocytic Leukemia (CLL), Controls Establishment of Follicular and Marginal Zone B Cell Compartments in Mice 129
Very poor outcome and chemoresistance of acute myeloid leukemia patients with TP53 mutations: Correlation with complex karyotype and clinical outcome 127
Survival analysis of 409 consecutive patients with newly diagnosed acute myeloid leukemia treated with intensive induction therapy, with or without the addition of gemtuzomab-ozagomicin (GO) 125
A Three-Genes Signature of Anti-Apoptotic Genes Showed Different Mechanisms in Preventing Apoptosis in Acute Myeloid Leukemia Cells and Could Provide an Useful Model to Establish the Proper BH3-Mimetich Drug or Combination 125
null 123
Novel fusion transcripts identified by RNAseq cooperate with somatic mutations in the pathogenesis of acute myeloid leukemia 122
Leukemia Associated TP53 Mutations in AML Patients ARE Strongly Associated with Complex Karyotype and Poor Outcome 121
Specific chromosomic alterations confer therapy resistance in a cohort of 49 patients with newly diagnosed acute myeloid leukemia treated with intensive chemotherapy 121
Uncovering the expression of circPVT1 in the extracellular vesicles of acute myeloid leukemia patients 121
Ultra-Deep Sequencing Strategy Is a Precious Tool to Find Small Clones Harbouring FLT3 Mutations in AML Patients 113
Impact on the Transcriptome of Proton Beam Irradiation Targeted at Healthy Cardiac Tissue of Mice 112
Gene expression signature of aneuploidy in acute myeloid leukemia 112
Xenograft models of chronic lymphocytic leukemia: problems, pitfalls and future directions 111
Lack of TIR8/SIGIRR triggers progression of chronic lymphocytic leukemia in mouse models 110
SIGLEC-G deficiency increases susceptibility to develop B-cell lymphoproliferative disorders 108
The role of Toll-like receptors in chronic B cell malignancies 108
Pharmacological interaction and side effects in oncohaematology: a retrospective observational study 107
Next-Generation Sequencing Analysis Revealed That BCL11B Chromosomal Translocation Cooperates with Point Mutations in the Pathogenesis of Acute Myeloid Leukemia 107
New JAK2 heterozygous loss: A role in overall survival in acute myeloid leukemia patients 106
The diverse roles of IRF4 in late germinal center B-cell differentiation 103
Mouse models in the study of chronic lymphocytic leukemia pathogenesis and therapy 102
Synthon-approach starting from amino-azaheterocycles to obtain new compounds with potential antiproliferative activity 100
Therapeutic Targeting of Acute Myeloid Leukemia by Gemtuzumab Ozogamicin 99
IRF4 controls the positioning of mature B cells in the lymphoid microenvironments by regulating NOTCH2 expression and activity 97
Combining Gene Expression Profiling and Integrated Multidisciplinary Approaches to Improve Prognosis Prediction in Multiple Myeloma 93
Hemiaminals from amino-azaheterocycles and chloral hydrate as synthons for the access to novel compounds with potential biological activity 91
Germinal center B cell maintenance and differentiation are controlled by distinct NF- B transcription factor subunits 90
Release of IFNg by Acute Myeloid Leukemia Cells Remodels Bone Marrow Immune Microenvironment by Inducing Regulatory T Cells 88
Novel Mouse Models of Chronic Lymphocytic Leukemia (CLL) Unravel the Molecular Mechanisms Controlling Bone Marrow Involvement by Leukemic B Cells 82
Differential Expression and Non-Redundant Functions of NF-kappa B Transcription Factor Subunits in Germinal Center (GC) B Cell Subpopulations 79
Kevetrin induces apoptosis in TP53 wild-type and mutant acute myeloid leukemia cells 75
The human Smoothened inhibitor PF-04449913 induces exit from quiescence and loss of multipotent Drosophila hematopoietic progenitor cells 66
PNH clones prevalence study in ph-negative myeloproliferative neoplasms: a multicenter Italian study 65
Potential CDC20 inhibitors: synthesis and biological evaluation of Apcin analogues 61
Pharmacological Inhibition of WIP1 Sensitizes Acute Myeloid Leukemia Cells to the MDM2 Inhibitor Nutlin-3a 60
Rearrangements of ATP5L‐KMT2A in acute lymphoblastic leukaemia 50
Patient and carer involvement in the formulation of research questions: findings from the Italian guideline on palliative care in adults with glioma 45
Totale 14.919
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Categoria #
all - tutte 40.083
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 40.083
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20211.497 0 0 0 0 0 78 44 105 146 65 93 966
2021/20221.892 253 55 109 185 191 94 46 101 84 101 351 322
2022/20232.182 238 310 122 301 176 178 58 109 365 57 167 101
2023/2024654 22 99 32 84 41 159 38 57 32 39 22 29
2024/20252.413 62 347 227 147 251 78 267 113 29 270 137 485
2025/20262.685 597 498 453 401 609 127 0 0 0 0 0 0
Totale 14.948