CRIS Current Research Information System

BAIULA, MONICA
 Distribuzione geografica
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Continente #
NA - Nord America 5.003
AS - Asia 4.609
EU - Europa 3.836
AF - Africa 475
Continente sconosciuto - Info sul continente non disponibili 330
SA - Sud America 274
OC - Oceania 9
Totale 14.536
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Nazione #
US - Stati Uniti d'America 4.904
SG - Singapore 1.293
CN - Cina 1.235
IT - Italia 1.155
VN - Vietnam 1.060
GB - Regno Unito 798
DE - Germania 457
HK - Hong Kong 312
FR - Francia 260
IN - India 214
SE - Svezia 211
RU - Federazione Russa 187
BR - Brasile 183
TG - Togo 171
IE - Irlanda 160
UA - Ucraina 137
CI - Costa d'Avorio 123
NL - Olanda 114
JP - Giappone 84
KR - Corea 83
FI - Finlandia 79
ZA - Sudafrica 76
BG - Bulgaria 68
BD - Bangladesh 59
CA - Canada 59
JO - Giordania 49
EE - Estonia 47
SC - Seychelles 46
ID - Indonesia 34
NG - Nigeria 34
AR - Argentina 32
PH - Filippine 29
HR - Croazia 24
TR - Turchia 23
CH - Svizzera 21
PK - Pakistan 21
TH - Thailandia 21
BE - Belgio 20
ES - Italia 20
IQ - Iraq 18
PL - Polonia 17
AT - Austria 16
MX - Messico 16
CL - Cile 13
TW - Taiwan 12
PE - Perù 11
IR - Iran 10
PT - Portogallo 10
RO - Romania 10
SA - Arabia Saudita 10
EC - Ecuador 9
CO - Colombia 8
IL - Israele 8
MY - Malesia 8
AU - Australia 7
JM - Giamaica 7
VE - Venezuela 7
CR - Costa Rica 6
AE - Emirati Arabi Uniti 5
LB - Libano 5
PY - Paraguay 5
UZ - Uzbekistan 5
EG - Egitto 4
ET - Etiopia 4
LT - Lituania 4
MA - Marocco 4
CZ - Repubblica Ceca 3
DO - Repubblica Dominicana 3
GR - Grecia 3
GT - Guatemala 3
HU - Ungheria 3
SI - Slovenia 3
TN - Tunisia 3
UY - Uruguay 3
AO - Angola 2
DZ - Algeria 2
EU - Europa 2
GY - Guiana 2
KE - Kenya 2
LK - Sri Lanka 2
MD - Moldavia 2
NO - Norvegia 2
NZ - Nuova Zelanda 2
RS - Serbia 2
SX - ???statistics.table.value.countryCode.SX??? 2
TT - Trinidad e Tobago 2
AM - Armenia 1
AZ - Azerbaigian 1
BY - Bielorussia 1
CG - Congo 1
CY - Cipro 1
DK - Danimarca 1
GE - Georgia 1
GF - Guiana Francese 1
KH - Cambogia 1
LC - Santa Lucia 1
LU - Lussemburgo 1
LY - Libia 1
MM - Myanmar 1
MW - Malawi 1
Totale 14.204
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Città #
Singapore 883
Southend 665
Ashburn 448
Bologna 390
San Jose 374
Fairfield 373
Chandler 368
Santa Clara 325
Hong Kong 293
Ho Chi Minh City 272
Hanoi 220
Lomé 171
Beijing 170
Princeton 169
Hefei 157
Wilmington 155
Council Bluffs 154
Houston 154
Dublin 149
Seattle 147
Woodbridge 141
Cambridge 126
Abidjan 123
Ann Arbor 106
Boardman 101
Lauterbourg 97
Dong Ket 85
Dallas 81
Nanjing 79
Milan 77
Jacksonville 73
Los Angeles 73
Tokyo 71
Westminster 69
Sofia 68
Seoul 63
Helsinki 60
Frankfurt am Main 57
Padova 56
New York 53
Berlin 51
Amman 49
Saint Petersburg 44
Shanghai 44
Bremen 36
Buffalo 36
Medford 36
Da Nang 35
Redondo Beach 34
Jinan 33
Redmond 33
Shenyang 33
Hebei 31
San Diego 31
Turin 31
Abeokuta 30
Nanchang 28
São Paulo 28
Munich 27
Haiphong 26
Rome 26
Guangzhou 24
Jakarta 24
Zhengzhou 24
Tianjin 23
Biên Hòa 20
Des Moines 20
Falls Church 20
Modena 19
Redwood City 18
Chicago 17
Rimini 17
Changsha 16
Toronto 16
Bengaluru 15
Brussels 15
Denver 15
Forlì 15
Hangzhou 15
London 15
Mülheim 15
Norwalk 15
Jiaxing 14
Johannesburg 14
Nuremberg 14
Olalla 14
San Francisco 14
Haikou 13
Shenzhen 13
Yubileyny 13
Manchester 12
Phoenix 12
Bern 11
Bühl 11
Can Tho 11
Falkenstein 11
Quận Bình Thạnh 11
Atlanta 10
Bangkok 10
Hyderabad 10
Totale 9.014
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Nome #
Targeting integrins αvβ3 and α5β1 with new β-lactam derivatives 297
Can integrin agonists have cards to play against cancer? A literature survey of small molecules integrin activators. 280
Synthesis and Biological Evaluation of Nonpeptide alpha-v-beta-3/alpha-5-beta-1 Integrin Dual Antagonists containing 5,6-Dihydropyridin-2-one Scaffolds 279
Leukocyte Integrin Antagonists as a Novel Option to Treat Dry Age-Related Macular Degeneration 278
Dehydro-beta-proline Containing Alpha-4-beta-1 Integrin Antagonists: Stereochemical Recognition in Ligand-Receptor Interplay 275
Could Dissecting the Molecular Framework of β-Lactam Integrin Ligands Enhance Selectivity? 256
Conjecturing about Small-Molecule Agonists and Antagonists of α4β1 Integrin: From Mechanistic Insight to Potential Therapeutic Applications 249
CSF tau is associated with impaired cortical plasticity, cognitive decline and astrocyte survival only in APOE4-positive Alzheimer's disease 249
Chiral β-lactam-based integrin ligands through Lipase-catalysed kinetic resolution and their enantioselective receptor response 246
New β-Lactam Derivatives Modulate Cell Adhesion and Signaling Mediated by RGD-Binding and Leukocyte Integrins 241
5-aminomethyloxazolidine-2,4-dione hybrid α/β-dipeptide scaffolds as inductors of constrained conformations: Applications to the synthesis of integrin antagonists 238
Nociceptin/orphanin FQ antagonizes lipopolysaccharide-stimulated proliferation, migration and inflammatory signaling in human glioblastoma U87 cells 238
α-linolenic acid-valproic acid conjugates: Toward single-molecule polypharmacology for multiple sclerosis 228
DS-70, a novel and potent α4 integrin antagonist, is an effective treatment for experimental allergic conjunctivitis in guinea pigs 222
β-Arrestin 2-mediated heterologous desensitization of IGF-IR by prolonged exposure of SH-SY5Y neuroblastoma cells to a mu opioid agonist 221
Therapeutic Targeting of Eosinophil Adhesion and Accumulation in Allergic Conjunctivitis 219
REST is up-regulated by epidermal growth factor in HeLa cells and inhibits apoptosis by influencing histone H3 acetylation 214
Transcription factor REST negatively influences the protein kinase C-dependent up-regulation of human mu-opioid receptor gene transcription 210
Functional Selectivity and Antinociceptive Effects of a Novel KOPr Agonist 210
The Bacterial Toxin CNF1 Protects Human Neuroblastoma SH-SY5Y Cells against 6-Hydroxydopamine-Induced Cell Damage: The Hypothesis of CNF1-Promoted Autophagy as an Antioxidant Strategy 208
Antiangiogenic Effect of Dual/Selective α5β1/αvβ3 Integrin Antagonists Designed on Partially Modified Retro-Inverso Cyclotetrapeptide Mimetics 207
Design of α/β-hybrid peptide ligands of α4β1 integrin equipped with a linkable side chain for chemoselective biofunctionalization of microstructured materials 200
Integrin-mediated adhesive properties of neutrophils are reduced by hyperbaric oxygen therapy in patients with chronic non-healing wound 199
Agonist-Regulated Internalization and desensitization of the Human Nociceptin Receptor Expressed in CHO Cells 189
Expression of the repressor element-1 silencing transcription factor (REST) is influenced by insulin-like growth factor-I in differentiating human neuroblastoma cells. 186
Synthesis and assay of retro-α4β1 integrin-targeting motifs 186
Contribution of alpha4beta1 integrin to the antiallergic effect of levocabastine 185
Modulation of αvβ3- and α5β1-integrin-mediated adhesion by dehydro-β-amino acids containing peptidomimetics 182
Identification of c[D-Trp-Phe-β-Ala-β-Ala], the First κ-Opioid Receptor-Specific Negative Allosteric Modulator 181
Eosinophil as a cellular target of the ocular anti-allergic action of mapracorat, a novel selective glucocorticoid receptor agonist 179
Design, Pharmacological Characterization, and Molecular Docking of Minimalist Peptidomimetic Antagonists of α4β1 Integrin 178
Phase II drugs under investigation for allergic conjunctivitis 175
Agonist-regulated endocytosis and desensitization of the human nociceptin receptor 170
Design and Pharmacological Characterization of α4β1 Integrin Cyclopeptide Agonists: Computational Investigation of Ligand Determinants for Agonism versus Antagonism 169
Prodynorphin-derived peptides 168
Role of nociceptin/orphanin FQ in thermoregulation 168
NEW PEPTIDOMIMETIC α4β1-INTEGRIN ANTAGONISTS FOR REDUCING INFLAMMATION AND ALLERGIC REACTIONS 167
Inhibition of cancer cell adhesion by heterochiral Pro-containing RGD mimetics. 164
Selective detection of α4β1 integrin (VLA-4)-expressing cells using peptide-functionalized nanostructured materials mimicking endothelial surfaces adjacent to inflammatory sites 164
Development of new beta-lactam-based integrin ligands: Synthesis and Applications 164
New coumarin-based anti-inflammatory drug: putative antagonist of the integrins alpha(L)beta(2) and alpha(M)beta(2). 162
Development of isoxazoline-containing peptidomimetics as dual alpha-v-beta-3 and alpha-5-beta-1 integrin ligands. 156
Design and synthesis of Alpha-v-beta-3 and Alpha-5-beta-1 integrin ligands as delivery systems for fluorescent molecules 154
Dehydro-beta-amino acids as scaffolds for the preparation of alpha-v-beta-3, alpha-5-beta-1 and alpha-4-beta-1 integrin ligands 153
TARGETING INTEGRINS WITH NEW BETA-LACTAM DERIVATIVES 153
Transcriptional activation of human mu-opioid receptor gene by insulin-like growth factor-I in neuronal cells is modulated by the transcription factor REST 151
Synthesis of Enantiomerically Pure alpha-v-beta-3 Integrin ligands Based on a 5,6-Dihydropyridin-2-one Scaffold. 150
Mapracorat, a novel non-steroidal selective glucocorticoid receptor agonist for the treatment of allergic conjunctivitis 144
Side chain effect in the modulation of αvβ3/α5β1 integrin activity via clickable isoxazoline-RGD-mimetics: development of molecular delivery systems 142
Molecular View on the iRGD Peptide Binding Mechanism: Implications for Integrin Activity and Selectivity Profiles 138
Selective Integrin Ligands Promote Cell Internalization of the Antineoplastic Agent Fluorouracil 138
Expression of the transcription factor REST at different stages of neuronal differentiation: contribution of PKC and WNT/-catenin signaling 136
Peptidomimetic Scaffolds for the Discovery of New Bioactive Compounds. Cyclotetrapeptide Analogues Based on a 13-Membered, Partially Modified Retro-Inverso Structure. Applications to the synthesis of Cancer Cell Adhesion Inhibitors 135
Editorial: Integrin Ligands and Their Bioconjugate Systems: Synthesis, Conformation, and Biological Activity 132
Inhibition of Toll-like Receptor 4 (TLR4)-induced NF-kB activation by NOP is lost in human glioblastoma cells chronically exposed to LPS. 132
Synthesis of new beta-lactam-based integrin ligands conjugated to cytotoxic agents 132
Monitoring opioid receptor interaction in living cells by bioluminescence resonance energy transfer (bret) 129
Peptidomimetic probes for modulating α4β1 integrin activity 127
Targeting integrins with new beta-lactam derivatives 126
Dehydro-beta-amino acid containing peptidomimetics as integrin receptor ligands 123
Targeting integrins with new beta-lactam derivatives 122
Quantitative Systems Pharmacology and Biased Agonism at Opioid Receptors: A Potential Avenue for Improved Analgesics 121
Targeting Integrins With New Beta-Lactam Derivatives 119
Molecular Mechanisms Mediating Nociceptin/Orphanin FQ Receptor Signaling, Desensitization and Internalization. 116
Protein Kinase C-dependent up-regulation of human mu-opioid receptor gene (OPRM1) transcription is negatively influenced by the transcription factor REST 114
Design, synthesis and in vitro evaluation of tumor homing agents by conjugation of integrin ligands to diagnostics and cytotoxic drugs 114
Ocular anti-allergic action of mapracorat, a novel selective glucocorticoid receptor agonist, involves eosinophil's apoptosis. 112
The ocular antiallergic action of mapracorat, a novel selective glucocorticoid receptor agonist, involves eosinophils and mast cells: evidence from human cells in vitro and an animal model 109
An in vitro assay to study the role of opioids in modulating immune cell adhesion 107
Novel Agonist Integrin Ligands: Synthesis, Biology & Applications 105
null 105
Mapracorat, a selective glucocorticoid receptor agonist, causes apoptosis of eosinophils infiltrating the conjunctiva in late phase experimental ocular allergy 104
Pro-inflammatory stimuli increase mu-opioid receptor (MOR) number on cell surface of human glioblastoma cells but hamper opioid agonist-induced intracellular signaling. G-protein-coupled-receptors: from structural insights to functional mechanisms 104
Monitoring opioid receptor dimerization in living cells by bioluminescence resonance energy transfer (BRET) 103
Genomic and non-genomic effects of anabolic steroids on opioid receptor gene expression in neuronal cells 102
TNF-alpha-induced MOR up-regulation in human glioblastoma cells is coupled to a loss of MOR-activated signalling to intracellular effectors 101
Novel Ligands Targeting alpha(4)beta(1) Integrin: Therapeutic Applications and Perspectives 101
PKC modulation of mu-opioid receptor gene (OPRM1) transcription is influenced by the transcription factor REST 100
New βeta-lactam derivatives targeting RGD-binding and leukocyte integrins 100
SYNTHESIS OF NEW FLUORESCENT INTEGRIN AGONISTS WITH A BETA-LACTAM SCAFFOLD 99
Peripheral antinociceptive effects of the cyclic endomorphin-1 analog c[YpwFG] in a mouse visceral pain model 99
Targeting α4β1 integrin: from cyclic to linear ligands, effects of chemical modifications 99
Insulin-like Growth Factor I (IGF-I) modulates hMOR transcription in neuronal cells: role of STAT3 97
Experimental pharmacotherapy for dry eye disease: A review 96
New 4-aminoproline-based small molecule cyclopeptidomimetics as potential modulators of α4β1 integrin 96
null 93
Mesenchymal stem cell secretome to control inflammation in allergic conjunctivitis 83
Antifibrotic Efficacy of a Nintedanib–Peptide Conjugate and Diagnostic Potential of a Fluorescent Companion Probe Targeting αVβ6 Integrin in Idiopathic Pulmonary Fibrosis 82
Functional cross-talk between TLR4 and NOPr in human glial cells. 80
Evaluation of New β -Lactam Derivatives’ Effects on α4β1 and αMβ2 Leukocyte Integrin-Mediated Immune Cells Activation and Migration 61
Pharmacological characterization of selective α4β1 integrin antagonists 58
α4β1 integrin targeting ligands for selective antineoplastic drug delivery in cancer cells 58
null 54
Leukocyte Integrins Targeting Ligands as an Innovative Therapeutic Approach for the Treatment of Inflammatory-based Diseases 53
Questing for Integrin Targeting Theranostics for Cancer Cell-Selective Molecules 17
Totale 14.536
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Categoria #
all - tutte 39.570
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 39.570
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.447 0 80 102 64 151 88 54 195 73 104 231 305
2022/20231.808 165 289 93 237 119 162 91 91 368 39 100 54
2023/2024614 29 75 28 51 57 129 40 54 39 33 45 34
2024/20252.129 105 294 174 163 408 101 178 59 12 158 73 404
2025/20264.945 412 467 356 421 520 242 554 242 956 369 223 183
2026/2027307 131 176 0 0 0 0 0 0 0 0 0 0
Totale 14.536