CRIS Current Research Information System

PERINI, GIOVANNI
 Distribuzione geografica
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Continente #
NA - Nord America 5.239
EU - Europa 4.112
AS - Asia 3.333
AF - Africa 356
SA - Sud America 221
OC - Oceania 23
Continente sconosciuto - Info sul continente non disponibili 5
Totale 13.289
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Nazione #
US - Stati Uniti d'America 5.184
IT - Italia 1.413
SG - Singapore 1.000
CN - Cina 952
GB - Regno Unito 698
VN - Vietnam 615
SE - Svezia 510
DE - Germania 453
HK - Hong Kong 289
IN - India 207
FR - Francia 165
RU - Federazione Russa 157
BR - Brasile 141
CI - Costa d'Avorio 133
IE - Irlanda 131
UA - Ucraina 96
NL - Olanda 94
ZA - Sudafrica 73
TG - Togo 71
FI - Finlandia 69
JO - Giordania 64
EE - Estonia 54
BG - Bulgaria 47
ES - Italia 47
BE - Belgio 45
AR - Argentina 42
CA - Canada 42
NG - Nigeria 36
CH - Svizzera 35
IR - Iran 30
SC - Seychelles 30
JP - Giappone 29
TR - Turchia 27
AT - Austria 26
KR - Corea 26
AU - Australia 22
ID - Indonesia 22
PK - Pakistan 18
HR - Croazia 16
PL - Polonia 16
BD - Bangladesh 15
CL - Cile 10
MX - Messico 10
CO - Colombia 8
RO - Romania 7
AE - Emirati Arabi Uniti 6
GR - Grecia 6
MY - Malesia 6
EC - Ecuador 5
LT - Lituania 5
PE - Perù 5
CZ - Repubblica Ceca 4
DK - Danimarca 4
EU - Europa 4
IQ - Iraq 4
PY - Paraguay 4
SY - Repubblica araba siriana 4
DZ - Algeria 3
KE - Kenya 3
TN - Tunisia 3
VE - Venezuela 3
AZ - Azerbaigian 2
EG - Egitto 2
GI - Gibilterra 2
KG - Kirghizistan 2
LA - Repubblica Popolare Democratica del Laos 2
LB - Libano 2
LU - Lussemburgo 2
MA - Marocco 2
NO - Norvegia 2
PT - Portogallo 2
SA - Arabia Saudita 2
TW - Taiwan 2
UY - Uruguay 2
UZ - Uzbekistan 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AL - Albania 1
BA - Bosnia-Erzegovina 1
BN - Brunei Darussalam 1
BO - Bolivia 1
BS - Bahamas 1
DO - Repubblica Dominicana 1
HN - Honduras 1
IL - Israele 1
LV - Lettonia 1
MD - Moldavia 1
NP - Nepal 1
NZ - Nuova Zelanda 1
PH - Filippine 1
RS - Serbia 1
SK - Slovacchia (Repubblica Slovacca) 1
TH - Thailandia 1
Totale 13.289
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Città #
Singapore 674
Southend 628
Fairfield 591
Ashburn 572
Chandler 477
Houston 381
Bologna 367
Hong Kong 287
Dong Ket 285
Woodbridge 270
Wilmington 254
Seattle 246
Ann Arbor 239
Santa Clara 230
Cambridge 190
Beijing 161
Princeton 159
Abidjan 133
Dublin 131
Boardman 124
Ho Chi Minh City 85
Hefei 81
Dallas 80
Milan 80
Nanjing 78
Lomé 71
Westminster 68
Padova 64
Amman 63
Helsinki 49
Los Angeles 49
Berlin 47
New York 47
Sofia 46
Brussels 42
Buffalo 42
Bremen 41
Jacksonville 41
Hanoi 40
San Diego 38
Hyderabad 35
Abeokuta 34
Naples 33
Saint Petersburg 33
Barcelona 30
Shanghai 30
Shenyang 30
Hebei 29
Jinan 29
Bari 28
Chicago 28
Florence 28
Rome 28
Seoul 26
Redwood City 25
Tokyo 25
Guangzhou 24
Redmond 24
Redondo Beach 24
Falls Church 23
Toronto 23
Zhengzhou 23
Nanchang 21
Frankfurt am Main 20
Falkenstein 19
Munich 19
Nuremberg 18
Turin 18
Vienna 17
Norwalk 16
Çankaya 16
Des Moines 15
Jakarta 15
São Paulo 15
Phoenix 14
Turku 14
Medford 13
Olalla 13
San Francisco 13
Tianjin 13
Amsterdam 12
Bern 12
Brooklyn 12
Hangzhou 12
Mülheim 12
Napoli 12
Philadelphia 12
Reggio Emilia 12
Changsha 11
Wuhan 11
Yubileyny 11
Dearborn 10
Jiaxing 10
Mercato San Severino 10
Palermo 10
Parma 10
Vicenza 10
Avellino 9
Düsseldorf 9
Ludwigshafen am Rhein 9
Totale 8.668
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Nome #
Analisi Genetica Avanzata 614
Single-cell gene network analysis and transcriptional landscape of MYCN-amplified neuroblastoma cell lines 335
MAX to MYCN intracellular ratio drives the aggressive phenotype and clinical outcome of high risk neuroblastoma 276
Histone deacetylases (HDACs): Evolution, specificity, role in transcriptional complexes, and pharmacological actionability 244
Association between imatinib transporters and metabolizing enzymes genotype and response in newly diagnosed chronic myeloid leukemia patients receiving imatinib therapy 242
Inhibition of polyamine synthesis and uptake reduces tumor progression and prolongs survival in mouse models of neuroblastoma 234
c-MYC oncoprotein dictates transcriptional profiles of ATP-binding cassette transporter genes in Chronic Myelogenous Leukemia CD34+ hematopoietic progenitor cells 228
ABCC multidrug transporters in childhood neuroblastoma: influence on tumor biology and clinical outcome, independent of cytotoxic drug efflux 206
Lysine-specific demethylase (LSD1/KDM1A) and MYCN cooperatively repress tumor suppressor genes in neuroblastoma 204
MYCN acts as a direct co-regulator of p53 in MYCN amplified neuroblastoma 204
In vivo transcriptional regulation of N-Myc target genes is controlled by E-box methylation 203
HDAC4: a key factor underlying brain developmental alterations in CDKL5 disorder 203
The C-Terminal Domain of CENP-C Displays Multiple and Critical Functions for Mammalian Centromere Formation. 203
The absence of dystrophin brain isoform expression in healthy human heart ventricles explains the pathogenesis of 5' X-linked dilated cardiomyopathy 201
A SP1/MIZ1/MYCN repression complex recruits HDAC1 at the TRKA and p75NTR promoters and affects neuroblastoma malignancy by inhibiting the cell response to NGF 198
A new BCR-ABL1 Drosophila model as a powerful tool to elucidate pathogenesis and progression of chronic myeloid leukemia 198
ARF Loss, a Negative Prognostic Factor in Philadelphia-Positive Acute Lymphoblastic Leukemia, May Be Efficiently Overcome by the Small Molecule MDM2 Antagonist RG7112 196
Transcriptional and epigenetic analyses of the DMD locus reveal novel cis‑acting DNA elements that govern muscle dystrophin expression 193
CDKL5, a novel MYCN-repressed gene, blocks cell cycle and promotes differentiation of neuronal cells 192
A genome-scale shRNA screen identifies GSK3 as a critical regulator of p75NTR transcription in high risk neuroblastoma 192
The amyloid precursor protein (APP) triplicated gene impairs neuronal precursor differentiation and neurite development through two different domains in the Ts65Dn mouse model for down syndrome. 189
Activation of tissue transglutaminase transcription by histone deacetylase inhibition as a therapeutic approach for Myc oncogenesis 189
The long noncoding RNA lncNB1 promotes tumorigenesis by interacting with ribosomal protein RPL35 187
The DMD Locus Harbours Multiple Long Non-Coding RNAs Which Orchestrate and Control Transcription of Muscle Dystrophin mRNA Isoforms. 185
The transcriptional co-repressor Runx1t1 is essential for MYCN-driven neuroblastoma tumorigenesis 181
JMJD6 is a tumorigenic factor and therapeutic target in neuroblastoma 179
Nitric oxide control of MYCN expression and multi drug resistance genes in tumours of neural origin. 177
MYCN promotes neuroblastoma malignancy by establishing a regulatory circuit with transcription factor AP4 177
APP-dependent up-regulation of Ptch1 underlies proliferation impairment of neural precursors in Down syndrome. 176
Targeting the p53-MDM2 interaction by the small-molecule MDM2 antagonist Nutlin-3a: A new challenged target therapy in adult Philadelphia positive acute lymphoblastic leukemia patients 173
IKAROS deletions dictate a unique gene expression signature in patients with adult B-cell acute lymphoblastic leukemia. 173
The histone methyltransferase DOT1L promotes neuroblastoma by regulating gene transcription 172
A critical appraisal of tools available for monitoring epigenetic changes in clinical samples from patients with myeloid malignancies. 169
MYCN Amplification, along with Wild-Type RB1 Expression, Enhances CDK4/6 Inhibitors’ Efficacy in Neuroblastoma Cells 168
Drugging MYCN oncogenic signalling through the MYCN-PA2G4 binding interface 166
The Hidden Genomic and Transcriptomic Plasticity of Giant Marker Chromosomes in Cancer 164
SIRT1 Promotes N-Myc Oncogenesis through a Positive Feedback Loop Involving the Effects of MKP3 and ERK on N-Myc Protein Stability. 163
Functional cooperation between TrkA and p75NTR accelerates neuronal differentiation by increased transcription of GAP-43 and p21(CIP/WAF) genes via ERK1/2 and AP-1 activities 162
Association between transporters genotype and response to the treatment in a subset of previously untreated chronic myeloid leukemia patients enrolled into the tops trial. 161
Epigenetic origin of evolutionary novel centromeres 159
Centromere sliding on a mammalian chromosome 155
Direct and coordinate regulation of ATP-binding cassette transporter genes by Myc factors generates specific transcription signatures that significantly affect the chemoresistance phenotype of cancer cells 155
A g316a polymorphism in the ornithine decarboxylase gene promoter modulates mycn‐driven childhood neuroblastoma 154
Effects of a novel long noncoding RNA, lncUSMycN, on N-Myc expression and neuroblastoma progression 153
SKP2 is a direct transcriptional target of MYCN and a potential therapeutic target in neuroblastoma 153
N-Myc Regulates Expression of the Detoxifying Enzyme Glutathione Transferase GSTP1, a Marker of Poor Outcome in Neuroblastoma 151
WDR5 Supports an N-Myc Transcriptional Complex That Drives a Protumorigenic Gene Expression Signature in Neuroblastoma 150
Transcriptional upregulation of histone deacetylase 2 promotes Myc-induced oncogenic effects 148
MYC-driven neuroblastomas are addicted to a telomerase-independent function of dyskerin 148
Repurposing a psychoactive drug for children with cancer: p27 Kip1-dependent inhibition of metastatic neuroblastomas by Prozac 147
PRDM15 is a key regulator of metabolism critical to sustain B-cell lymphomagenesis 146
Down-Regulation of BMI-1 Is a New Marker of Sensitivity to Mdm2 Inhibition in B-Acute Lymphoblastic Leukemia. 144
Single-Cell Sequencing Identifies Master Regulators Affected by Panobinostat in Neuroblastoma Cells 140
Altered gene silencing and human diseases. 140
p53 is a direct transcriptional target of MYCN in neuroblastoma. 139
Down-Regulation of BMI-1 Is a New Marker of Sensitivity to Mdm2 Inhibition in B-Acute Lymphoblastic Leukemia. 138
Mutations in the 5' UTR of ANKRD26, the ankirin repeat domain 26 gene, cause an autosomal-dominant form of inherited thrombocytopenia, THC2 136
Physical interaction between MYCN oncogene and polycomb repressive complex 2 (PRC2) in neuroblastoma: functional and therapeutic implications. 136
MYCN amplification confers enhanced folate dependence and methotrexate sensitivity in neuroblastoma 136
Ring chromosomes, breakpoint clusters, and neocentromeres in sarcomas 134
Association between genotypes and response to the treatment in a subset of previously untreated chronic myeloid leukemia patients enrolled into the TOPS trial. 131
IKZF1 (IKAROS) Deletions Are Independent On BCR-ABL1 Rearrangement and Are Associated with a Peculiar Gene Expression Signature and Poor Prognosis in Adult B-Progenitor Acute Lymphoblastic Leukemia (ALL) Patients. 131
MYCN-driven fatty acid uptake is a metabolic vulnerability in neuroblastoma 128
Targeting oncogenic transcriptional networks in neuroblastoma: From N-Myc to epigenetic drugs 128
Letting the breaks off MYCN 127
IKZF1 (IKAROS) Deletions Are Independent On BCR-ABL1 Rearrangement and Are Associated with a Peculiar Gene Expression Signature and Poor Prognosis in Adult B-Progenitor Acute Lymphoblastic Leukemia (ALL) Patients 126
CENP-C binds the alpha-satellite DNA in vivo at specific centromere domains 126
null 123
CHAF1A Blocks Neuronal Differentiation and Promotes Neuroblastoma Oncogenesis via Metabolic Reprogramming 120
Myc proteins in cell biology and pathology 116
Gfi-1 inhibits proliferation and colony formation of p210BCR/ABL-expressing cells via transcriptional repression of STAT 5 and Mcl-1. 114
Expression of spliced oncogenic Ikaros isoforms in Philadelphia-positive acute lymphoblastic leukemia patients treated with tyrosine kinase inhibitors: implications for a new mechanism of resistance. 114
Restoration of the molecular clock is tumor suppressive in neuroblastoma 108
null 101
Unveiling Early Differentiation Induced by Histone Deacetylase Inhibitors in Neuroblastoma Cell Lines: A Single-Cell Transcriptomics Approach 95
Frodi scientifiche? Ricerca e responsabilità sociale dello scienziato 92
MYCN-mediated transcriptional repression in neuroblastoma: the other side of the coin. 85
In vivo functional dissection of human inner kinetochore protein CENP-C 83
null 82
Non-canonical activating roles of RCoR2 sustain transcription in adrenergic neuroblastoma 72
The human Smoothened inhibitor PF-04449913 induces exit from quiescence and loss of multipotent Drosophila hematopoietic progenitor cells 69
null 64
Non-Coding RNAs in Muscle Dystrophies. 59
The cell-permeable iron chelator M606 inhibits MYCN-driven neuroblastoma via an E2F3-mediated response 24
Gene selection for prediction of transcriptome signal based on a machine learning approach 11
Totale 13.568
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Categoria #
all - tutte 36.388
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 36.388
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021997 0 0 0 0 0 67 47 77 119 86 126 475
2021/20221.850 194 78 134 140 148 124 59 114 112 167 328 252
2022/20232.093 193 291 98 292 175 158 52 110 406 96 93 129
2023/2024690 78 78 45 40 82 124 38 58 27 34 51 35
2024/20252.210 131 253 216 168 345 117 241 84 44 128 83 400
2025/20262.196 253 332 380 382 580 269 0 0 0 0 0 0
Totale 13.568