CRIS Current Research Information System

PERINI, GIOVANNI
 Distribuzione geografica
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Continente #
NA - Nord America 5.969
AS - Asia 4.756
EU - Europa 4.621
AF - Africa 383
SA - Sud America 276
OC - Oceania 29
Continente sconosciuto - Info sul continente non disponibili 5
Totale 16.039
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Nazione #
US - Stati Uniti d'America 5.880
IT - Italia 1.670
SG - Singapore 1.286
VN - Vietnam 1.221
CN - Cina 1.143
GB - Regno Unito 760
SE - Svezia 511
DE - Germania 478
HK - Hong Kong 315
FR - Francia 249
IN - India 235
BR - Brasile 180
RU - Federazione Russa 159
CI - Costa d'Avorio 135
IE - Irlanda 133
BD - Bangladesh 113
NL - Olanda 106
UA - Ucraina 96
FI - Finlandia 87
ZA - Sudafrica 79
TG - Togo 72
JO - Giordania 68
JP - Giappone 65
CA - Canada 63
ES - Italia 55
EE - Estonia 54
BG - Bulgaria 48
BE - Belgio 47
TR - Turchia 45
AR - Argentina 43
KR - Corea 41
CH - Svizzera 39
NG - Nigeria 36
SC - Seychelles 36
PK - Pakistan 33
IR - Iran 30
PH - Filippine 30
AT - Austria 29
AU - Australia 28
ID - Indonesia 24
TH - Thailandia 23
PL - Polonia 20
MX - Messico 19
HR - Croazia 17
IQ - Iraq 16
TW - Taiwan 13
CL - Cile 10
GR - Grecia 10
CO - Colombia 9
LT - Lituania 9
RO - Romania 9
PE - Perù 8
VE - Venezuela 8
CZ - Repubblica Ceca 7
EC - Ecuador 7
TN - Tunisia 7
AE - Emirati Arabi Uniti 6
MY - Malesia 6
PY - Paraguay 6
SM - San Marino 6
UZ - Uzbekistan 6
SY - Repubblica araba siriana 5
DK - Danimarca 4
DZ - Algeria 4
EU - Europa 4
NP - Nepal 4
SA - Arabia Saudita 4
UY - Uruguay 4
AZ - Azerbaigian 3
ET - Etiopia 3
KE - Kenya 3
KG - Kirghizistan 3
LB - Libano 3
EG - Egitto 2
GI - Gibilterra 2
KZ - Kazakistan 2
LA - Repubblica Popolare Democratica del Laos 2
LU - Lussemburgo 2
MA - Marocco 2
MN - Mongolia 2
NO - Norvegia 2
PS - Palestinian Territory 2
PT - Portogallo 2
RS - Serbia 2
SK - Slovacchia (Repubblica Slovacca) 2
TT - Trinidad e Tobago 2
ZW - Zimbabwe 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AL - Albania 1
AO - Angola 1
BA - Bosnia-Erzegovina 1
BN - Brunei Darussalam 1
BO - Bolivia 1
BS - Bahamas 1
CR - Costa Rica 1
DO - Repubblica Dominicana 1
GE - Georgia 1
GH - Ghana 1
HN - Honduras 1
IL - Israele 1
Totale 16.029
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Città #
Singapore 930
Ashburn 632
Southend 628
Fairfield 591
Chandler 477
Bologna 427
Houston 383
Hong Kong 301
Dong Ket 285
Woodbridge 270
Wilmington 254
Santa Clara 252
San Jose 251
Seattle 248
Ann Arbor 239
Ho Chi Minh City 232
Cambridge 190
Hanoi 184
Beijing 171
Princeton 159
Abidjan 135
Dublin 133
Boardman 125
Milan 94
Dallas 85
Hefei 81
Nanjing 80
Lauterbourg 76
Los Angeles 73
Lomé 72
New York 69
Westminster 68
Amman 67
Helsinki 67
Padova 64
Council Bluffs 61
Tokyo 56
Buffalo 50
Berlin 48
Rome 46
Sofia 46
Da Nang 44
Bremen 42
Brussels 42
Jacksonville 41
Shanghai 41
San Diego 40
Florence 39
Naples 39
Frankfurt am Main 38
Chicago 36
Hyderabad 35
Abeokuta 34
Saint Petersburg 33
Bari 32
Guangzhou 32
Jinan 31
Barcelona 30
Dundee 30
Shenyang 30
Hebei 29
Toronto 28
Seoul 26
Redwood City 25
Redmond 24
Redondo Beach 24
Falls Church 23
Nanchang 23
São Paulo 23
Zhengzhou 23
Amsterdam 21
Turin 21
Munich 20
Falkenstein 19
Haiphong 19
Nuremberg 19
Orem 19
Vienna 19
Phoenix 18
Rimini 18
Des Moines 17
Norwalk 16
Çankaya 16
Jakarta 15
San Francisco 15
Hangzhou 14
London 14
Medford 14
Tianjin 14
Turku 14
Brooklyn 13
Olalla 13
Palermo 13
Philadelphia 13
Reggio Emilia 13
Bern 12
Hải Dương 12
Johannesburg 12
Mülheim 12
Napoli 12
Totale 10.104
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Nome #
Analisi Genetica Avanzata 667
Single-cell gene network analysis and transcriptional landscape of MYCN-amplified neuroblastoma cell lines 377
MAX to MYCN intracellular ratio drives the aggressive phenotype and clinical outcome of high risk neuroblastoma 304
Inhibition of polyamine synthesis and uptake reduces tumor progression and prolongs survival in mouse models of neuroblastoma 284
Histone deacetylases (HDACs): Evolution, specificity, role in transcriptional complexes, and pharmacological actionability 277
Association between imatinib transporters and metabolizing enzymes genotype and response in newly diagnosed chronic myeloid leukemia patients receiving imatinib therapy 276
c-MYC oncoprotein dictates transcriptional profiles of ATP-binding cassette transporter genes in Chronic Myelogenous Leukemia CD34+ hematopoietic progenitor cells 262
The transcriptional co-repressor Runx1t1 is essential for MYCN-driven neuroblastoma tumorigenesis 249
The C-Terminal Domain of CENP-C Displays Multiple and Critical Functions for Mammalian Centromere Formation. 248
HDAC4: a key factor underlying brain developmental alterations in CDKL5 disorder 243
ABCC multidrug transporters in childhood neuroblastoma: influence on tumor biology and clinical outcome, independent of cytotoxic drug efflux 239
Lysine-specific demethylase (LSD1/KDM1A) and MYCN cooperatively repress tumor suppressor genes in neuroblastoma 236
Activation of tissue transglutaminase transcription by histone deacetylase inhibition as a therapeutic approach for Myc oncogenesis 232
In vivo transcriptional regulation of N-Myc target genes is controlled by E-box methylation 230
JMJD6 is a tumorigenic factor and therapeutic target in neuroblastoma 230
Targeting the p53-MDM2 interaction by the small-molecule MDM2 antagonist Nutlin-3a: A new challenged target therapy in adult Philadelphia positive acute lymphoblastic leukemia patients 227
ARF Loss, a Negative Prognostic Factor in Philadelphia-Positive Acute Lymphoblastic Leukemia, May Be Efficiently Overcome by the Small Molecule MDM2 Antagonist RG7112 227
The absence of dystrophin brain isoform expression in healthy human heart ventricles explains the pathogenesis of 5' X-linked dilated cardiomyopathy 226
A new BCR-ABL1 Drosophila model as a powerful tool to elucidate pathogenesis and progression of chronic myeloid leukemia 224
MYCN acts as a direct co-regulator of p53 in MYCN amplified neuroblastoma 223
The long noncoding RNA lncNB1 promotes tumorigenesis by interacting with ribosomal protein RPL35 220
A SP1/MIZ1/MYCN repression complex recruits HDAC1 at the TRKA and p75NTR promoters and affects neuroblastoma malignancy by inhibiting the cell response to NGF 219
Transcriptional and epigenetic analyses of the DMD locus reveal novel cis‑acting DNA elements that govern muscle dystrophin expression 217
The amyloid precursor protein (APP) triplicated gene impairs neuronal precursor differentiation and neurite development through two different domains in the Ts65Dn mouse model for down syndrome. 215
CDKL5, a novel MYCN-repressed gene, blocks cell cycle and promotes differentiation of neuronal cells 214
MYCN Amplification, along with Wild-Type RB1 Expression, Enhances CDK4/6 Inhibitors’ Efficacy in Neuroblastoma Cells 213
A genome-scale shRNA screen identifies GSK3 as a critical regulator of p75NTR transcription in high risk neuroblastoma 212
The histone methyltransferase DOT1L promotes neuroblastoma by regulating gene transcription 210
The DMD Locus Harbours Multiple Long Non-Coding RNAs Which Orchestrate and Control Transcription of Muscle Dystrophin mRNA Isoforms. 209
Drugging MYCN oncogenic signalling through the MYCN-PA2G4 binding interface 209
Nitric oxide control of MYCN expression and multi drug resistance genes in tumours of neural origin. 205
Targeting oncogenic transcriptional networks in neuroblastoma: From N-Myc to epigenetic drugs 204
Functional cooperation between TrkA and p75NTR accelerates neuronal differentiation by increased transcription of GAP-43 and p21(CIP/WAF) genes via ERK1/2 and AP-1 activities 202
IKAROS deletions dictate a unique gene expression signature in patients with adult B-cell acute lymphoblastic leukemia. 200
APP-dependent up-regulation of Ptch1 underlies proliferation impairment of neural precursors in Down syndrome. 198
MYCN promotes neuroblastoma malignancy by establishing a regulatory circuit with transcription factor AP4 197
SIRT1 Promotes N-Myc Oncogenesis through a Positive Feedback Loop Involving the Effects of MKP3 and ERK on N-Myc Protein Stability. 196
A critical appraisal of tools available for monitoring epigenetic changes in clinical samples from patients with myeloid malignancies. 191
Centromere sliding on a mammalian chromosome 190
WDR5 Supports an N-Myc Transcriptional Complex That Drives a Protumorigenic Gene Expression Signature in Neuroblastoma 190
Non-canonical activating roles of RCoR2 sustain transcription in adrenergic neuroblastoma 188
The Hidden Genomic and Transcriptomic Plasticity of Giant Marker Chromosomes in Cancer 188
A g316a polymorphism in the ornithine decarboxylase gene promoter modulates mycn‐driven childhood neuroblastoma 188
Epigenetic origin of evolutionary novel centromeres 185
Direct and coordinate regulation of ATP-binding cassette transporter genes by Myc factors generates specific transcription signatures that significantly affect the chemoresistance phenotype of cancer cells 183
Association between transporters genotype and response to the treatment in a subset of previously untreated chronic myeloid leukemia patients enrolled into the tops trial. 182
N-Myc Regulates Expression of the Detoxifying Enzyme Glutathione Transferase GSTP1, a Marker of Poor Outcome in Neuroblastoma 180
SKP2 is a direct transcriptional target of MYCN and a potential therapeutic target in neuroblastoma 179
Repurposing a psychoactive drug for children with cancer: p27 Kip1-dependent inhibition of metastatic neuroblastomas by Prozac 179
Effects of a novel long noncoding RNA, lncUSMycN, on N-Myc expression and neuroblastoma progression 177
PRDM15 is a key regulator of metabolism critical to sustain B-cell lymphomagenesis 176
MYC-driven neuroblastomas are addicted to a telomerase-independent function of dyskerin 173
IKZF1 (IKAROS) Deletions Are Independent On BCR-ABL1 Rearrangement and Are Associated with a Peculiar Gene Expression Signature and Poor Prognosis in Adult B-Progenitor Acute Lymphoblastic Leukemia (ALL) Patients. 173
Down-Regulation of BMI-1 Is a New Marker of Sensitivity to Mdm2 Inhibition in B-Acute Lymphoblastic Leukemia. 172
Physical interaction between MYCN oncogene and polycomb repressive complex 2 (PRC2) in neuroblastoma: functional and therapeutic implications. 171
Transcriptional upregulation of histone deacetylase 2 promotes Myc-induced oncogenic effects 168
p53 is a direct transcriptional target of MYCN in neuroblastoma. 168
MYCN-driven fatty acid uptake is a metabolic vulnerability in neuroblastoma 163
Ring chromosomes, breakpoint clusters, and neocentromeres in sarcomas 163
Down-Regulation of BMI-1 Is a New Marker of Sensitivity to Mdm2 Inhibition in B-Acute Lymphoblastic Leukemia. 163
Single-Cell Sequencing Identifies Master Regulators Affected by Panobinostat in Neuroblastoma Cells 160
Mutations in the 5' UTR of ANKRD26, the ankirin repeat domain 26 gene, cause an autosomal-dominant form of inherited thrombocytopenia, THC2 159
CENP-C binds the alpha-satellite DNA in vivo at specific centromere domains 159
MYCN amplification confers enhanced folate dependence and methotrexate sensitivity in neuroblastoma 158
CHAF1A Blocks Neuronal Differentiation and Promotes Neuroblastoma Oncogenesis via Metabolic Reprogramming 151
Altered gene silencing and human diseases. 150
Association between genotypes and response to the treatment in a subset of previously untreated chronic myeloid leukemia patients enrolled into the TOPS trial. 145
Letting the breaks off MYCN 143
IKZF1 (IKAROS) Deletions Are Independent On BCR-ABL1 Rearrangement and Are Associated with a Peculiar Gene Expression Signature and Poor Prognosis in Adult B-Progenitor Acute Lymphoblastic Leukemia (ALL) Patients 141
Restoration of the molecular clock is tumor suppressive in neuroblastoma 140
Myc proteins in cell biology and pathology 133
Expression of spliced oncogenic Ikaros isoforms in Philadelphia-positive acute lymphoblastic leukemia patients treated with tyrosine kinase inhibitors: implications for a new mechanism of resistance. 129
Gfi-1 inhibits proliferation and colony formation of p210BCR/ABL-expressing cells via transcriptional repression of STAT 5 and Mcl-1. 127
MYCN-mediated transcriptional repression in neuroblastoma: the other side of the coin. 125
Systematic Targeting of GD2‐Positive Neuroblastoma Tumors With a Photooncolytic Phage Nanovector Platform 124
null 123
Unveiling Early Differentiation Induced by Histone Deacetylase Inhibitors in Neuroblastoma Cell Lines: A Single-Cell Transcriptomics Approach 121
In vivo functional dissection of human inner kinetochore protein CENP-C 112
Frodi scientifiche? Ricerca e responsabilità sociale dello scienziato 109
The human Smoothened inhibitor PF-04449913 induces exit from quiescence and loss of multipotent Drosophila hematopoietic progenitor cells 106
null 101
Gene selection for prediction of transcriptome signal based on a machine learning approach 88
Non-Coding RNAs in Muscle Dystrophies. 88
null 82
The cell-permeable iron chelator M606 inhibits MYCN-driven neuroblastoma via an E2F3-mediated response 71
null 64
Deep learning for MYC binding site recognition 20
Totale 16.340
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Categoria #
all - tutte 42.131
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 42.131
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021475 0 0 0 0 0 0 0 0 0 0 0 475
2021/20221.850 194 78 134 140 148 124 59 114 112 167 328 252
2022/20232.093 193 291 98 292 175 158 52 110 406 96 93 129
2023/2024690 78 78 45 40 82 124 38 58 27 34 51 35
2024/20252.210 131 253 216 168 345 117 241 84 44 128 83 400
2025/20264.968 253 332 380 382 580 322 558 259 1.027 410 259 206
Totale 16.340