CRIS Current Research Information System

PERINI, GIOVANNI
 Distribuzione geografica
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Continente #
NA - Nord America 4.695
EU - Europa 3.473
AS - Asia 1.704
AF - Africa 226
OC - Oceania 20
SA - Sud America 20
Continente sconosciuto - Info sul continente non disponibili 5
Totale 10.143
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Nazione #
US - Stati Uniti d'America 4.665
IT - Italia 1.147
GB - Regno Unito 679
CN - Cina 586
SE - Svezia 506
VN - Vietnam 417
DE - Germania 373
SG - Singapore 361
IN - India 185
IE - Irlanda 131
FR - Francia 126
RU - Federazione Russa 101
UA - Ucraina 94
TG - Togo 71
ZA - Sudafrica 64
JO - Giordania 60
EE - Estonia 54
CI - Costa d'Avorio 48
BG - Bulgaria 46
FI - Finlandia 41
BE - Belgio 40
NG - Nigeria 35
CH - Svizzera 29
IR - Iran 29
CA - Canada 27
NL - Olanda 26
AU - Australia 19
ES - Italia 17
HR - Croazia 16
PK - Pakistan 15
ID - Indonesia 13
AT - Austria 11
TR - Turchia 8
CL - Cile 7
HK - Hong Kong 7
PL - Polonia 7
BR - Brasile 6
GR - Grecia 6
RO - Romania 6
MY - Malesia 5
SC - Seychelles 5
BD - Bangladesh 4
DK - Danimarca 4
EU - Europa 4
PE - Perù 4
CZ - Repubblica Ceca 3
LA - Repubblica Popolare Democratica del Laos 2
LB - Libano 2
LT - Lituania 2
LU - Lussemburgo 2
NO - Norvegia 2
SA - Arabia Saudita 2
TN - Tunisia 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AE - Emirati Arabi Uniti 1
AL - Albania 1
AR - Argentina 1
BA - Bosnia-Erzegovina 1
BO - Bolivia 1
BS - Bahamas 1
CO - Colombia 1
EG - Egitto 1
HN - Honduras 1
JP - Giappone 1
KR - Corea 1
MD - Moldavia 1
MX - Messico 1
NZ - Nuova Zelanda 1
PH - Filippine 1
PT - Portogallo 1
SY - Repubblica araba siriana 1
TH - Thailandia 1
TW - Taiwan 1
UZ - Uzbekistan 1
Totale 10.143
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Città #
Southend 628
Fairfield 591
Chandler 477
Ashburn 415
Houston 379
Singapore 329
Dong Ket 285
Bologna 282
Woodbridge 270
Wilmington 254
Seattle 245
Ann Arbor 239
Santa Clara 227
Cambridge 189
Princeton 159
Dublin 131
Boardman 121
Nanjing 78
Lomé 71
Westminster 68
Padova 64
Amman 60
Beijing 58
Milan 51
Abidjan 48
Berlin 47
Sofia 45
Bremen 41
Jacksonville 41
Helsinki 39
Brussels 37
San Diego 37
New York 36
Hyderabad 35
Abeokuta 34
Saint Petersburg 33
Naples 31
Hebei 29
Shenyang 29
Jinan 28
Redwood City 25
Redmond 24
Falls Church 23
Shanghai 23
Florence 22
Nanchang 21
Guangzhou 19
Zhengzhou 19
Rome 18
Turin 18
Toronto 17
Bari 16
Norwalk 16
Des Moines 15
Jakarta 13
Medford 13
Olalla 13
Bern 12
Mülheim 12
Napoli 12
Philadelphia 12
Los Angeles 11
Tianjin 11
Changsha 10
Dearborn 10
Jiaxing 10
Mercato San Severino 10
Vienna 10
Avellino 9
Hangzhou 9
Ludwigshafen am Rhein 9
Modena 9
Monmouth Junction 9
Paris 9
Vicenza 9
Frankfurt Am Main 8
Guesnain 8
Herne 8
Parma 8
Phoenix 8
Santa Maria Capua Vetere 8
Amsterdam 7
Ardabil 7
Haikou 7
Lanzhou 7
San Francisco 7
Venice 7
Wuhan 7
Aprilia 6
Bühl 6
Cesena 6
Falkenstein 6
Hong Kong 6
Ningbo 6
Ottawa 6
Salerno 6
San Mateo 6
Sialkot 6
Taiyuan 6
Valladolid 6
Totale 6.928
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Nome #
Analisi Genetica Avanzata 497
Single-cell gene network analysis and transcriptional landscape of MYCN-amplified neuroblastoma cell lines 276
MAX to MYCN intracellular ratio drives the aggressive phenotype and clinical outcome of high risk neuroblastoma 228
Association between imatinib transporters and metabolizing enzymes genotype and response in newly diagnosed chronic myeloid leukemia patients receiving imatinib therapy 199
c-MYC oncoprotein dictates transcriptional profiles of ATP-binding cassette transporter genes in Chronic Myelogenous Leukemia CD34+ hematopoietic progenitor cells 193
Histone deacetylases (HDACs): Evolution, specificity, role in transcriptional complexes, and pharmacological actionability 192
Inhibition of polyamine synthesis and uptake reduces tumor progression and prolongs survival in mouse models of neuroblastoma 185
ABCC multidrug transporters in childhood neuroblastoma: influence on tumor biology and clinical outcome, independent of cytotoxic drug efflux 175
MYCN acts as a direct co-regulator of p53 in MYCN amplified neuroblastoma 174
HDAC4: a key factor underlying brain developmental alterations in CDKL5 disorder 170
The absence of dystrophin brain isoform expression in healthy human heart ventricles explains the pathogenesis of 5' X-linked dilated cardiomyopathy 168
ARF Loss, a Negative Prognostic Factor in Philadelphia-Positive Acute Lymphoblastic Leukemia, May Be Efficiently Overcome by the Small Molecule MDM2 Antagonist RG7112 168
Lysine-specific demethylase (LSD1/KDM1A) and MYCN cooperatively repress tumor suppressor genes in neuroblastoma 166
A SP1/MIZ1/MYCN repression complex recruits HDAC1 at the TRKA and p75NTR promoters and affects neuroblastoma malignancy by inhibiting the cell response to NGF 162
The C-Terminal Domain of CENP-C Displays Multiple and Critical Functions for Mammalian Centromere Formation. 160
The amyloid precursor protein (APP) triplicated gene impairs neuronal precursor differentiation and neurite development through two different domains in the Ts65Dn mouse model for down syndrome. 157
A genome-scale shRNA screen identifies GSK3 as a critical regulator of p75NTR transcription in high risk neuroblastoma 157
CDKL5, a novel MYCN-repressed gene, blocks cell cycle and promotes differentiation of neuronal cells 156
Activation of tissue transglutaminase transcription by histone deacetylase inhibition as a therapeutic approach for Myc oncogenesis 152
The DMD Locus Harbours Multiple Long Non-Coding RNAs Which Orchestrate and Control Transcription of Muscle Dystrophin mRNA Isoforms. 151
MYCN promotes neuroblastoma malignancy by establishing a regulatory circuit with transcription factor AP4 149
A new BCR-ABL1 Drosophila model as a powerful tool to elucidate pathogenesis and progression of chronic myeloid leukemia 148
Nitric oxide control of MYCN expression and multi drug resistance genes in tumours of neural origin. 147
IKAROS deletions dictate a unique gene expression signature in patients with adult B-cell acute lymphoblastic leukemia. 145
APP-dependent up-regulation of Ptch1 underlies proliferation impairment of neural precursors in Down syndrome. 144
In vivo transcriptional regulation of N-Myc target genes is controlled by E-box methylation 143
A critical appraisal of tools available for monitoring epigenetic changes in clinical samples from patients with myeloid malignancies. 140
The histone methyltransferase DOT1L promotes neuroblastoma by regulating gene transcription 139
The long noncoding RNA lncNB1 promotes tumorigenesis by interacting with ribosomal protein RPL35 137
The Hidden Genomic and Transcriptomic Plasticity of Giant Marker Chromosomes in Cancer 136
SIRT1 Promotes N-Myc Oncogenesis through a Positive Feedback Loop Involving the Effects of MKP3 and ERK on N-Myc Protein Stability. 134
Functional cooperation between TrkA and p75NTR accelerates neuronal differentiation by increased transcription of GAP-43 and p21(CIP/WAF) genes via ERK1/2 and AP-1 activities 134
Association between transporters genotype and response to the treatment in a subset of previously untreated chronic myeloid leukemia patients enrolled into the tops trial. 132
Targeting the p53-MDM2 interaction by the small-molecule MDM2 antagonist Nutlin-3a: A new challenged target therapy in adult Philadelphia positive acute lymphoblastic leukemia patients 132
Centromere sliding on a mammalian chromosome 130
Effects of a novel long noncoding RNA, lncUSMycN, on N-Myc expression and neuroblastoma progression 129
SKP2 is a direct transcriptional target of MYCN and a potential therapeutic target in neuroblastoma 127
Altered gene silencing and human diseases. 126
JMJD6 is a tumorigenic factor and therapeutic target in neuroblastoma 126
Drugging MYCN oncogenic signalling through the MYCN-PA2G4 binding interface 125
N-Myc Regulates Expression of the Detoxifying Enzyme Glutathione Transferase GSTP1, a Marker of Poor Outcome in Neuroblastoma 124
null 123
Transcriptional and epigenetic analyses of the DMD locus reveal novel cis‑acting DNA elements that govern muscle dystrophin expression 123
Transcriptional upregulation of histone deacetylase 2 promotes Myc-induced oncogenic effects 122
Direct and coordinate regulation of ATP-binding cassette transporter genes by Myc factors generates specific transcription signatures that significantly affect the chemoresistance phenotype of cancer cells 122
Epigenetic origin of evolutionary novel centromeres 121
WDR5 Supports an N-Myc Transcriptional Complex That Drives a Protumorigenic Gene Expression Signature in Neuroblastoma 121
p53 is a direct transcriptional target of MYCN in neuroblastoma. 116
MYCN amplification confers enhanced folate dependence and methotrexate sensitivity in neuroblastoma 115
MYC-driven neuroblastomas are addicted to a telomerase-independent function of dyskerin 115
Ring chromosomes, breakpoint clusters, and neocentromeres in sarcomas 111
Association between genotypes and response to the treatment in a subset of previously untreated chronic myeloid leukemia patients enrolled into the TOPS trial. 109
Down-Regulation of BMI-1 Is a New Marker of Sensitivity to Mdm2 Inhibition in B-Acute Lymphoblastic Leukemia. 109
IKZF1 (IKAROS) Deletions Are Independent On BCR-ABL1 Rearrangement and Are Associated with a Peculiar Gene Expression Signature and Poor Prognosis in Adult B-Progenitor Acute Lymphoblastic Leukemia (ALL) Patients 107
Down-Regulation of BMI-1 Is a New Marker of Sensitivity to Mdm2 Inhibition in B-Acute Lymphoblastic Leukemia. 107
Mutations in the 5' UTR of ANKRD26, the ankirin repeat domain 26 gene, cause an autosomal-dominant form of inherited thrombocytopenia, THC2 105
CENP-C binds the alpha-satellite DNA in vivo at specific centromere domains 105
Repurposing a psychoactive drug for children with cancer: p27 Kip1-dependent inhibition of metastatic neuroblastomas by Prozac 105
IKZF1 (IKAROS) Deletions Are Independent On BCR-ABL1 Rearrangement and Are Associated with a Peculiar Gene Expression Signature and Poor Prognosis in Adult B-Progenitor Acute Lymphoblastic Leukemia (ALL) Patients. 103
Letting the breaks off MYCN 102
A g316a polymorphism in the ornithine decarboxylase gene promoter modulates mycn‐driven childhood neuroblastoma 102
Physical interaction between MYCN oncogene and polycomb repressive complex 2 (PRC2) in neuroblastoma: functional and therapeutic implications. 101
null 101
PRDM15 is a key regulator of metabolism critical to sustain B-cell lymphomagenesis 96
Gfi-1 inhibits proliferation and colony formation of p210BCR/ABL-expressing cells via transcriptional repression of STAT 5 and Mcl-1. 94
Expression of spliced oncogenic Ikaros isoforms in Philadelphia-positive acute lymphoblastic leukemia patients treated with tyrosine kinase inhibitors: implications for a new mechanism of resistance. 94
Myc proteins in cell biology and pathology 92
Targeting oncogenic transcriptional networks in neuroblastoma: From N-Myc to epigenetic drugs 84
null 82
CHAF1A Blocks Neuronal Differentiation and Promotes Neuroblastoma Oncogenesis via Metabolic Reprogramming 78
Frodi scientifiche? Ricerca e responsabilità sociale dello scienziato 68
Restoration of the molecular clock is tumor suppressive in neuroblastoma 65
null 64
Unveiling Early Differentiation Induced by Histone Deacetylase Inhibitors in Neuroblastoma Cell Lines: A Single-Cell Transcriptomics Approach 64
MYCN Amplification, along with Wild-Type RB1 Expression, Enhances CDK4/6 Inhibitors’ Efficacy in Neuroblastoma Cells 62
MYCN-driven fatty acid uptake is a metabolic vulnerability in neuroblastoma 56
Single-Cell Sequencing Identifies Master Regulators Affected by Panobinostat in Neuroblastoma Cells 52
MYCN-mediated transcriptional repression in neuroblastoma: the other side of the coin. 42
The transcriptional co-repressor Runx1t1 is essential for MYCN-driven neuroblastoma tumorigenesis 37
Non-Coding RNAs in Muscle Dystrophies. 34
In vivo functional dissection of human inner kinetochore protein CENP-C 33
The human Smoothened inhibitor PF-04449913 induces exit from quiescence and loss of multipotent Drosophila hematopoietic progenitor cells 29
Totale 10.404
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Categoria #
all - tutte 26.632
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 26.632
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201.312 0 0 0 0 0 0 291 314 319 161 85 142
2020/20211.442 227 101 50 38 29 67 47 77 119 86 126 475
2021/20221.850 194 78 134 140 148 124 59 114 112 167 328 252
2022/20232.093 193 291 98 292 175 158 52 110 406 96 93 129
2023/2024690 78 78 45 40 82 124 38 58 27 34 51 35
2024/20251.242 131 253 216 168 345 117 12 0 0 0 0 0
Totale 10.404