CRIS Current Research Information System

PERINI, GIOVANNI
 Distribuzione geografica
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Continente #
NA - Nord America 5.711
AS - Asia 4.649
EU - Europa 4.485
AF - Africa 382
SA - Sud America 268
OC - Oceania 27
Continente sconosciuto - Info sul continente non disponibili 5
Totale 15.527
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Nazione #
US - Stati Uniti d'America 5.642
IT - Italia 1.542
SG - Singapore 1.281
VN - Vietnam 1.219
CN - Cina 1.129
GB - Regno Unito 760
SE - Svezia 511
DE - Germania 478
HK - Hong Kong 306
FR - Francia 249
IN - India 234
BR - Brasile 173
RU - Federazione Russa 159
CI - Costa d'Avorio 135
IE - Irlanda 133
NL - Olanda 103
UA - Ucraina 96
FI - Finlandia 87
ZA - Sudafrica 79
TG - Togo 72
JO - Giordania 68
JP - Giappone 65
EE - Estonia 54
ES - Italia 54
CA - Canada 51
BG - Bulgaria 48
BE - Belgio 47
TR - Turchia 45
AR - Argentina 43
BD - Bangladesh 41
KR - Corea 41
CH - Svizzera 38
NG - Nigeria 36
SC - Seychelles 36
IR - Iran 30
PH - Filippine 30
PK - Pakistan 30
AT - Austria 29
AU - Australia 26
ID - Indonesia 24
TH - Thailandia 23
PL - Polonia 19
HR - Croazia 17
IQ - Iraq 16
MX - Messico 13
TW - Taiwan 13
CL - Cile 10
GR - Grecia 10
CO - Colombia 9
RO - Romania 9
LT - Lituania 8
PE - Perù 8
VE - Venezuela 8
EC - Ecuador 7
TN - Tunisia 7
AE - Emirati Arabi Uniti 6
CZ - Repubblica Ceca 6
MY - Malesia 6
SM - San Marino 6
UZ - Uzbekistan 6
PY - Paraguay 5
SY - Repubblica araba siriana 5
DK - Danimarca 4
DZ - Algeria 4
EU - Europa 4
NP - Nepal 4
SA - Arabia Saudita 4
UY - Uruguay 4
AZ - Azerbaigian 3
ET - Etiopia 3
KE - Kenya 3
KG - Kirghizistan 3
LB - Libano 3
EG - Egitto 2
GI - Gibilterra 2
KZ - Kazakistan 2
LA - Repubblica Popolare Democratica del Laos 2
LU - Lussemburgo 2
MA - Marocco 2
MN - Mongolia 2
NO - Norvegia 2
PS - Palestinian Territory 2
PT - Portogallo 2
RS - Serbia 2
SK - Slovacchia (Repubblica Slovacca) 2
A2 - ???statistics.table.value.countryCode.A2??? 1
AL - Albania 1
AO - Angola 1
BA - Bosnia-Erzegovina 1
BN - Brunei Darussalam 1
BO - Bolivia 1
BS - Bahamas 1
DO - Repubblica Dominicana 1
GE - Georgia 1
GH - Ghana 1
HN - Honduras 1
IL - Israele 1
JM - Giamaica 1
LV - Lettonia 1
MD - Moldavia 1
Totale 15.519
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Città #
Singapore 926
Southend 628
Ashburn 617
Fairfield 591
Chandler 477
Bologna 403
Houston 382
Hong Kong 292
Dong Ket 285
Woodbridge 270
Wilmington 254
Seattle 246
Santa Clara 243
Ann Arbor 239
Ho Chi Minh City 232
San Jose 223
Cambridge 190
Hanoi 182
Beijing 165
Princeton 159
Abidjan 135
Dublin 133
Boardman 124
Milan 87
Dallas 82
Hefei 81
Nanjing 80
Lauterbourg 76
Lomé 72
Westminster 68
Amman 67
Helsinki 67
Padova 64
New York 58
Tokyo 56
Los Angeles 54
Council Bluffs 51
Berlin 48
Sofia 46
Da Nang 44
Buffalo 43
Bremen 42
Brussels 42
Jacksonville 41
Florence 39
Shanghai 39
Frankfurt am Main 38
Rome 38
San Diego 38
Hyderabad 35
Abeokuta 34
Chicago 33
Naples 33
Saint Petersburg 33
Guangzhou 32
Jinan 31
Barcelona 30
Dundee 30
Shenyang 30
Hebei 29
Bari 28
Seoul 26
Redwood City 25
Toronto 25
Redmond 24
Redondo Beach 24
Falls Church 23
Nanchang 23
Zhengzhou 23
Amsterdam 21
Munich 20
São Paulo 20
Falkenstein 19
Haiphong 19
Nuremberg 19
Vienna 19
Turin 18
Des Moines 17
Orem 17
Norwalk 16
Çankaya 16
Jakarta 15
Phoenix 15
Hangzhou 14
London 14
Tianjin 14
Turku 14
Medford 13
Olalla 13
San Francisco 13
Bern 12
Brooklyn 12
Hải Dương 12
Johannesburg 12
Mülheim 12
Napoli 12
Paris 12
Philadelphia 12
Reggio Emilia 12
Wuhan 12
Totale 9.894
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Nome #
Analisi Genetica Avanzata 657
Single-cell gene network analysis and transcriptional landscape of MYCN-amplified neuroblastoma cell lines 371
MAX to MYCN intracellular ratio drives the aggressive phenotype and clinical outcome of high risk neuroblastoma 303
Inhibition of polyamine synthesis and uptake reduces tumor progression and prolongs survival in mouse models of neuroblastoma 281
Association between imatinib transporters and metabolizing enzymes genotype and response in newly diagnosed chronic myeloid leukemia patients receiving imatinib therapy 271
Histone deacetylases (HDACs): Evolution, specificity, role in transcriptional complexes, and pharmacological actionability 263
c-MYC oncoprotein dictates transcriptional profiles of ATP-binding cassette transporter genes in Chronic Myelogenous Leukemia CD34+ hematopoietic progenitor cells 260
The C-Terminal Domain of CENP-C Displays Multiple and Critical Functions for Mammalian Centromere Formation. 238
ABCC multidrug transporters in childhood neuroblastoma: influence on tumor biology and clinical outcome, independent of cytotoxic drug efflux 235
The transcriptional co-repressor Runx1t1 is essential for MYCN-driven neuroblastoma tumorigenesis 232
Lysine-specific demethylase (LSD1/KDM1A) and MYCN cooperatively repress tumor suppressor genes in neuroblastoma 231
HDAC4: a key factor underlying brain developmental alterations in CDKL5 disorder 228
In vivo transcriptional regulation of N-Myc target genes is controlled by E-box methylation 226
ARF Loss, a Negative Prognostic Factor in Philadelphia-Positive Acute Lymphoblastic Leukemia, May Be Efficiently Overcome by the Small Molecule MDM2 Antagonist RG7112 226
JMJD6 is a tumorigenic factor and therapeutic target in neuroblastoma 226
The absence of dystrophin brain isoform expression in healthy human heart ventricles explains the pathogenesis of 5' X-linked dilated cardiomyopathy 225
A new BCR-ABL1 Drosophila model as a powerful tool to elucidate pathogenesis and progression of chronic myeloid leukemia 223
MYCN acts as a direct co-regulator of p53 in MYCN amplified neuroblastoma 217
A SP1/MIZ1/MYCN repression complex recruits HDAC1 at the TRKA and p75NTR promoters and affects neuroblastoma malignancy by inhibiting the cell response to NGF 217
Transcriptional and epigenetic analyses of the DMD locus reveal novel cis‑acting DNA elements that govern muscle dystrophin expression 215
The long noncoding RNA lncNB1 promotes tumorigenesis by interacting with ribosomal protein RPL35 215
Activation of tissue transglutaminase transcription by histone deacetylase inhibition as a therapeutic approach for Myc oncogenesis 214
The amyloid precursor protein (APP) triplicated gene impairs neuronal precursor differentiation and neurite development through two different domains in the Ts65Dn mouse model for down syndrome. 213
CDKL5, a novel MYCN-repressed gene, blocks cell cycle and promotes differentiation of neuronal cells 212
MYCN Amplification, along with Wild-Type RB1 Expression, Enhances CDK4/6 Inhibitors’ Efficacy in Neuroblastoma Cells 211
A genome-scale shRNA screen identifies GSK3 as a critical regulator of p75NTR transcription in high risk neuroblastoma 211
Targeting the p53-MDM2 interaction by the small-molecule MDM2 antagonist Nutlin-3a: A new challenged target therapy in adult Philadelphia positive acute lymphoblastic leukemia patients 207
The DMD Locus Harbours Multiple Long Non-Coding RNAs Which Orchestrate and Control Transcription of Muscle Dystrophin mRNA Isoforms. 207
Drugging MYCN oncogenic signalling through the MYCN-PA2G4 binding interface 206
Nitric oxide control of MYCN expression and multi drug resistance genes in tumours of neural origin. 203
Functional cooperation between TrkA and p75NTR accelerates neuronal differentiation by increased transcription of GAP-43 and p21(CIP/WAF) genes via ERK1/2 and AP-1 activities 199
APP-dependent up-regulation of Ptch1 underlies proliferation impairment of neural precursors in Down syndrome. 198
IKAROS deletions dictate a unique gene expression signature in patients with adult B-cell acute lymphoblastic leukemia. 197
The histone methyltransferase DOT1L promotes neuroblastoma by regulating gene transcription 197
MYCN promotes neuroblastoma malignancy by establishing a regulatory circuit with transcription factor AP4 194
SIRT1 Promotes N-Myc Oncogenesis through a Positive Feedback Loop Involving the Effects of MKP3 and ERK on N-Myc Protein Stability. 192
A critical appraisal of tools available for monitoring epigenetic changes in clinical samples from patients with myeloid malignancies. 188
The Hidden Genomic and Transcriptomic Plasticity of Giant Marker Chromosomes in Cancer 188
Targeting oncogenic transcriptional networks in neuroblastoma: From N-Myc to epigenetic drugs 184
WDR5 Supports an N-Myc Transcriptional Complex That Drives a Protumorigenic Gene Expression Signature in Neuroblastoma 183
A g316a polymorphism in the ornithine decarboxylase gene promoter modulates mycn‐driven childhood neuroblastoma 182
Epigenetic origin of evolutionary novel centromeres 181
Direct and coordinate regulation of ATP-binding cassette transporter genes by Myc factors generates specific transcription signatures that significantly affect the chemoresistance phenotype of cancer cells 181
Association between transporters genotype and response to the treatment in a subset of previously untreated chronic myeloid leukemia patients enrolled into the tops trial. 177
N-Myc Regulates Expression of the Detoxifying Enzyme Glutathione Transferase GSTP1, a Marker of Poor Outcome in Neuroblastoma 176
Centromere sliding on a mammalian chromosome 176
SKP2 is a direct transcriptional target of MYCN and a potential therapeutic target in neuroblastoma 176
Effects of a novel long noncoding RNA, lncUSMycN, on N-Myc expression and neuroblastoma progression 175
Repurposing a psychoactive drug for children with cancer: p27 Kip1-dependent inhibition of metastatic neuroblastomas by Prozac 175
PRDM15 is a key regulator of metabolism critical to sustain B-cell lymphomagenesis 173
MYC-driven neuroblastomas are addicted to a telomerase-independent function of dyskerin 172
Physical interaction between MYCN oncogene and polycomb repressive complex 2 (PRC2) in neuroblastoma: functional and therapeutic implications. 170
Down-Regulation of BMI-1 Is a New Marker of Sensitivity to Mdm2 Inhibition in B-Acute Lymphoblastic Leukemia. 168
IKZF1 (IKAROS) Deletions Are Independent On BCR-ABL1 Rearrangement and Are Associated with a Peculiar Gene Expression Signature and Poor Prognosis in Adult B-Progenitor Acute Lymphoblastic Leukemia (ALL) Patients. 167
Transcriptional upregulation of histone deacetylase 2 promotes Myc-induced oncogenic effects 165
Ring chromosomes, breakpoint clusters, and neocentromeres in sarcomas 162
p53 is a direct transcriptional target of MYCN in neuroblastoma. 162
Down-Regulation of BMI-1 Is a New Marker of Sensitivity to Mdm2 Inhibition in B-Acute Lymphoblastic Leukemia. 160
Mutations in the 5' UTR of ANKRD26, the ankirin repeat domain 26 gene, cause an autosomal-dominant form of inherited thrombocytopenia, THC2 158
Single-Cell Sequencing Identifies Master Regulators Affected by Panobinostat in Neuroblastoma Cells 157
MYCN-driven fatty acid uptake is a metabolic vulnerability in neuroblastoma 157
MYCN amplification confers enhanced folate dependence and methotrexate sensitivity in neuroblastoma 157
CENP-C binds the alpha-satellite DNA in vivo at specific centromere domains 156
Altered gene silencing and human diseases. 149
Association between genotypes and response to the treatment in a subset of previously untreated chronic myeloid leukemia patients enrolled into the TOPS trial. 145
CHAF1A Blocks Neuronal Differentiation and Promotes Neuroblastoma Oncogenesis via Metabolic Reprogramming 145
Letting the breaks off MYCN 143
IKZF1 (IKAROS) Deletions Are Independent On BCR-ABL1 Rearrangement and Are Associated with a Peculiar Gene Expression Signature and Poor Prognosis in Adult B-Progenitor Acute Lymphoblastic Leukemia (ALL) Patients 139
Restoration of the molecular clock is tumor suppressive in neuroblastoma 132
Myc proteins in cell biology and pathology 131
Non-canonical activating roles of RCoR2 sustain transcription in adrenergic neuroblastoma 127
Expression of spliced oncogenic Ikaros isoforms in Philadelphia-positive acute lymphoblastic leukemia patients treated with tyrosine kinase inhibitors: implications for a new mechanism of resistance. 127
Gfi-1 inhibits proliferation and colony formation of p210BCR/ABL-expressing cells via transcriptional repression of STAT 5 and Mcl-1. 125
null 123
MYCN-mediated transcriptional repression in neuroblastoma: the other side of the coin. 119
Unveiling Early Differentiation Induced by Histone Deacetylase Inhibitors in Neuroblastoma Cell Lines: A Single-Cell Transcriptomics Approach 116
In vivo functional dissection of human inner kinetochore protein CENP-C 109
Frodi scientifiche? Ricerca e responsabilità sociale dello scienziato 107
null 101
The human Smoothened inhibitor PF-04449913 induces exit from quiescence and loss of multipotent Drosophila hematopoietic progenitor cells 91
Systematic Targeting of GD2‐Positive Neuroblastoma Tumors With a Photooncolytic Phage Nanovector Platform 88
null 82
Non-Coding RNAs in Muscle Dystrophies. 81
Gene selection for prediction of transcriptome signal based on a machine learning approach 65
null 64
The cell-permeable iron chelator M606 inhibits MYCN-driven neuroblastoma via an E2F3-mediated response 58
Deep learning for MYC binding site recognition 12
Totale 15.826
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Categoria #
all - tutte 39.840
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 39.840
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021687 0 0 0 0 0 0 0 0 0 86 126 475
2021/20221.850 194 78 134 140 148 124 59 114 112 167 328 252
2022/20232.093 193 291 98 292 175 158 52 110 406 96 93 129
2023/2024690 78 78 45 40 82 124 38 58 27 34 51 35
2024/20252.210 131 253 216 168 345 117 241 84 44 128 83 400
2025/20264.454 253 332 380 382 580 322 558 259 1.027 361 0 0
Totale 15.826