CRIS Current Research Information System

BELLUTI, FEDERICA
 Distribuzione geografica
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Continente #
NA - Nord America 7.278
AS - Asia 6.337
EU - Europa 4.374
AF - Africa 368
SA - Sud America 292
OC - Oceania 12
Continente sconosciuto - Info sul continente non disponibili 3
Totale 18.664
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Nazione #
US - Stati Uniti d'America 7.147
VN - Vietnam 1.704
SG - Singapore 1.617
CN - Cina 1.580
IT - Italia 1.030
GB - Regno Unito 892
DE - Germania 588
HK - Hong Kong 381
SE - Svezia 358
IN - India 285
FR - Francia 251
UA - Ucraina 241
RU - Federazione Russa 233
BR - Brasile 189
NL - Olanda 161
IE - Irlanda 138
BD - Bangladesh 126
JP - Giappone 124
CI - Costa d'Avorio 116
KR - Corea 113
FI - Finlandia 103
ZA - Sudafrica 99
JO - Giordania 97
CA - Canada 92
TG - Togo 70
BG - Bulgaria 64
EE - Estonia 61
PH - Filippine 47
AR - Argentina 46
ID - Indonesia 44
ES - Italia 39
PL - Polonia 35
CH - Svizzera 34
SC - Seychelles 32
IR - Iran 30
TR - Turchia 30
PK - Pakistan 29
TH - Thailandia 28
IQ - Iraq 25
AT - Austria 24
MX - Messico 24
BE - Belgio 20
GR - Grecia 20
CZ - Repubblica Ceca 18
EC - Ecuador 17
HR - Croazia 17
EG - Egitto 14
MY - Malesia 13
CO - Colombia 12
TW - Taiwan 12
NG - Nigeria 11
SA - Arabia Saudita 11
LT - Lituania 9
AU - Australia 8
LB - Libano 8
VE - Venezuela 8
CL - Cile 7
KE - Kenya 7
KZ - Kazakistan 7
HU - Ungheria 6
PT - Portogallo 6
DZ - Algeria 5
MD - Moldavia 5
PS - Palestinian Territory 5
PY - Paraguay 5
RO - Romania 5
TN - Tunisia 5
AL - Albania 4
GT - Guatemala 4
AE - Emirati Arabi Uniti 3
BO - Bolivia 3
BY - Bielorussia 3
ET - Etiopia 3
NZ - Nuova Zelanda 3
OM - Oman 3
RS - Serbia 3
UZ - Uzbekistan 3
A2 - ???statistics.table.value.countryCode.A2??? 2
AO - Angola 2
AZ - Azerbaigian 2
CR - Costa Rica 2
HN - Honduras 2
KW - Kuwait 2
LK - Sri Lanka 2
MA - Marocco 2
NO - Norvegia 2
NP - Nepal 2
PA - Panama 2
PE - Perù 2
UY - Uruguay 2
AM - Armenia 1
BA - Bosnia-Erzegovina 1
BB - Barbados 1
CW - ???statistics.table.value.countryCode.CW??? 1
DO - Repubblica Dominicana 1
GH - Ghana 1
GI - Gibilterra 1
GY - Guiana 1
HT - Haiti 1
JM - Giamaica 1
Totale 18.656
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Città #
Singapore 1.110
Southend 755
Ashburn 721
Fairfield 583
Chandler 560
San Jose 497
Santa Clara 373
Ho Chi Minh City 363
Hong Kong 363
Bologna 340
Hanoi 327
Woodbridge 308
Seattle 278
Wilmington 274
Houston 261
Hefei 237
Dong Ket 227
Cambridge 219
Ann Arbor 193
Beijing 189
Princeton 188
Jacksonville 154
New York 153
Boardman 147
Council Bluffs 146
Dublin 138
Abidjan 116
Tokyo 101
Los Angeles 98
Seoul 97
Amman 96
Nanjing 85
Helsinki 82
Westminster 81
Lauterbourg 80
Dallas 76
Buffalo 72
Lomé 70
Padova 68
Berlin 64
Sofia 64
Munich 54
Jinan 52
Bremen 50
Da Nang 50
Milan 48
San Diego 46
Shenyang 45
Saint Petersburg 43
Redondo Beach 37
Frankfurt am Main 35
Guangzhou 35
Redmond 35
Haiphong 34
Nanchang 32
Mülheim 31
Tianjin 31
Hebei 30
Jakarta 30
Shanghai 29
Bern 28
Orem 26
Quận Bình Thạnh 26
São Paulo 25
Bengaluru 24
Changsha 24
Dearborn 24
Zhengzhou 24
Biên Hòa 23
Chicago 23
Jiaxing 23
Warsaw 23
Nuremberg 22
Hải Dương 21
Johannesburg 21
Medford 21
Montreal 21
Olalla 20
Rimini 20
Toronto 20
Brussels 19
London 19
Phoenix 19
Des Moines 18
Mahé 18
Atlanta 17
Redwood City 17
Can Tho 16
Rome 16
Sant Cugat del Vallès 16
Venezia 16
Shenzhen 15
Thái Nguyên 15
Boydton 14
Brooklyn 14
Falkenstein 14
Mountain View 14
Haikou 13
Kunming 13
Mexico City 13
Totale 11.876
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Nome #
1,4-dihydropyridine derivatives as calcium channel modulators: the role of 3-methoxy-flavone moiety 352
Discovery of novel benzofuran-based compounds with neuroprotective and immunomodulatory properties for Alzheimer's disease treatment 338
Multitarget Strategy to Address Alzheimer's Disease: Design, Synthesis, Biological Evaluation, and Computational Studies of Coumarin-Based Derivatives 295
Cholinesterase inhibitors: xanthostigmine derivatives blocking the acetylcholinesterase-induced beta-amyloid aggregation. 252
Structure-Activity Relationships and Binding Mode in the Human Acetylcholinesterase Active Site of Pseudo-Irreversible Inhibitors Related to Xanthostigmine 252
Progettazione e sintesi di derivati benzofuranici per la malattia di Alzheimer 241
Chitosan nanoparticles for lipophilic anticancer drug delivery: Development, characterization and in vitro studies on HT29 cancer cells 236
Design, synthesis and biological profile of new inhibitors of multidrug resistance associated proteins carrying a polycyclic scaffold 227
Targeting neuronal calcium channels and GSK3β for Alzheimer's disease with naturally-inspired Diels-Alder adducts 224
Analogues of the dual acetylcholinesterase inhibitor AP2238: synthesis and SAR 221
Benzophenones as xanthone-open model CYP11B1 inhibitors potentially useful for promoting wound healing 220
Versatility of the Curcumin Scaffold: Discovery of Potent and Balanced Dual BACE-1 and GSK-3β Inhibitors 218
Identification of chalcone-based antileishmanial agents targeting trypanothione reductase 218
Balanced dual acting compounds targeting aromatase and estrogen receptor α as an emerging therapeutic opportunity to counteract estrogen responsive breast cancer 216
Exploiting the chalcone scaffold to develop multifunctional agents for Alzheimer’s disease 215
Fatty Acid Amide Hydrolase (FAAH), Acetylcholinesterase (AChE), and Butyrylcholinesterase (BuChE): Networked Targets for the Development of Carbamates as Potential Anti-Alzheimer's Disease Agents 214
Identification of a new tamoxifen-xanthene hybrid as pro-apoptotic anticancer agent 209
Natural-like Chalcones with Antitumor Activity on Human MG63 Osteosarcoma Cells 209
Targeting the multifaceted neurotoxicity of Alzheimer's disease by tailored functionalisation of the curcumin scaffold 208
2-Arylbenzofuran-based molecules as multipotent Alzheimer's disease modifying agents 208
Development of a Focused Library of Triazole-Linked Privileged-Structure-Based Conjugates Leading to the Discovery of Novel Phenotypic Hits against Protozoan Parasitic Infections 207
Extensive SAR and computational studies of 3-{4-[(benzylmethylamino)methyl]phenyl}-6,7-dimethoxy-2H-2-chromenone (AP2238) derivatives. 200
SAR and binding mode at the h-AChE active site of pseudo-irreversible inhibitors related to Xanthostigmine 200
Naturally inspired molecules as multifunctional agents for Alzheimer's disease treatment 199
Benzophenone-based derivatives: A novel series of potent and selective dual inhibitors of acetylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation 197
Interplay Between Endocannabinoid System and Neurodegeneration: Focus on Polypharmacology 195
Cardiovascular profile of xanthone-based 1,4 dihydropyridines bearing a lidoflazine pharmacophore fragment 193
Curcumin-1,2,3-triazole conjugation for targeting the cancer apoptosis machinery. 192
Novel Curcumin-Diethyl Fumarate Hybrid as a Dualistic GSK-3β Inhibitor/Nrf2 Inducer for the Treatment of Parkinson's Disease 191
Complementary medicinal chemistry-driven strategies toward new antitrypanosomal and antileishmanial lead drug candidates 190
CHOLINESTERASE INHIBITORS: SAR AND ENZYME INHIBITORY ACTIVITY OF 3-[omega-(BENZYLMETHYLAMINO)ALKOXY]XANTHEN-9-ONES 186
Potent inhibition of human phosphodiesterase-5 by icariin derivatives 185
Enantioselective nonsteroidal aromatase inhibitors identified through a multidisciplinary medicinal chemistry approach 182
Chitosan nanoparticles for curcumin delivery: development, characterization and in-vitro studies on cancer cells 177
Single-digit nanomolar inhibitors lock the aromatase active site via a dualsteric targeting strategy 176
Potent inhibition of human phosphodiesterase-5 by icariin derivatives in an enzyme assay 176
Polycyclic maleimide-based derivatives as first dual modulators of neuronal calcium channels and GSK-3β for Alzheimer's disease treatment 174
New Coumarin derivatives as cholinergic and cannabinoid system modulators 174
Lead optimization providing a series of flavone derivatives as potent nonsteroidal inhibitors of the cytochrome P450 aromatase enzyme 173
Emerging targets in neurodegeneration: new opportunities for Alzheimer's disease treatment? 172
Nonsteroidal Aromatase inhibitors: synthesis and evaluation of new flavone derivatives 171
Homopterocarpanes as bridged triarylethylene analogues: synthesis and antagonistic effects in human MCF-7 breast cancer cells 171
Derivati a struttura benzofenonica come inibitori dell'acetilcolinesterasi 169
Multifaceted activity of polyciclic MDR revertant agents in drug-resistant leukemic cells: Role of the spacer 169
Fluorinated benzophenone derivatives: balanced multipotent agents for Alzheimer's disease 168
Multitarget Ligands in the Search for Novel Lead Candidates against Trypanosoma and Leishmania 167
Design, synthesis, and evaluation of benzophenone derivatives as novel acetylcholinesterase inhibitors 166
Conjugation of Quinones with Natural Polyamines: Toward an Expanded Antitrypanosomatid Profile 163
Imidazolylmethylbenzophenones as highly potent aromatase inhibitors. 162
Multitarget Compounds for Bipolar Disorder: From Rational Design to Preliminary Pharmacokinetic Evaluation 162
Reconsidering Aromatase for Breast Cancer Treatment: New Roles for an Old Target 162
Multi-target-directed coumarin derivatives: hAChE and BAC1 inhibitors as potential anti-Alzheimer compounds 161
Phenolic 1,3-diketones attenuate lipopolysaccharide-induced inflammatory response by an alternative magnesium-mediated mechanism 158
Improved eradication efficacy of a combination of newly identified antimicrobial agents in C. albicans and S. aureus mixed-species biofilm 157
In vitro studies of flavon-8-acetic acid analogues 155
New derivatives of xanthenone-4-acetic acid: synthesis, pharmacological profile and effect on TNF-alpha and NO production by human immune cells 155
Naturally Inspired Coumarin Derivatives in Alzheimer’s Disease Drug Discovery: Latest Advances and Current Challenges 153
Switching from Aromatase Inhibitors to Dual Targeting Flavonoid-Based Compounds for Breast Cancer Treatment 153
Studies on cytostatic and cytotoxic activity of new flavopiridol analogues 153
Hybrid drugs for Alzheimer's disease: new indanone derivatives bearing a pharmacophoric fragment of AP2238 153
Benzophenone derivatives as Inhibitors of Acetylcholinesterase 153
In vitro biological activity of new analogues of flavon-8-acetic acid 151
Functionalization of the chalcone scaffold for the discovery of novel lead compounds targeting fungal infections 151
From AChE to BACE1 inhibitors: The role of the amine on the indanone scaffold 148
Toward the Development of Dual-Targeted Glyceraldehyde-3-phosphate Dehydrogenase/Trypanothione Reductase Inhibitors againstTrypanosoma bruceiandTrypanosoma cruzi 148
Curcumin derivatives as beta-secretase (BACE1) inhibitors. 147
Flavonoid-inspired vascular disrupting agents: Exploring flavone-8-acetic acid and derivatives in the new century 147
Design, Synthesis, and Biological and Crystallographic Evaluation of Novel Inhibitors ofPlasmodium falciparumEnoyl-ACP-reductase (PfFabI) 146
Multi-target strategy to address Alzheimer’s disease: Design, synthesis and biological evaluation of new tacrine-based dimers 146
Hitting drug-resistant malaria infection with triazole-linked flavonoid–chloroquine hybrid compounds 145
High-throughput screening of beta-secretase inhibitors by multiwell FRET assay 145
New potent P-glycoprotein inhibitors carrying a polycyclic scaffold 145
Polycyclic Maleimide-based Scaffold as New Privileged Structure for Navigating the Cannabinoid System Opportunities 145
Targeting the Bacterial Membrane with a New Polycyclic Privileged Structure: A Powerful Tool To Face Staphylococcus aureus Infections 142
Design of Multifunctional Compounds for Cardiovascular Disease: From Natural Scaffolds to “Classical” Multitarget Approach 138
Modulation of Amyloid β-induced Microglia Activation and Neuronal Cell Death by Curcumin and Analogues 135
New potent inhibitors of cytochrome P450 aromatase 134
Novel highly potent and selective nonsteroidal aromatase inhibitors: synthesis, biological evaluation and structure-activity relationships investigation 133
Imidazolylmethylxanthones as potent inhibitors of cytochrome P450 aromatase 129
Chalcone-based carbamates for Alzheimer's disease treatment 129
Hybrid-Based Multi-Target Ligands for the Treatment of Alzheimer's Disease 126
Coumarin derivatives as potential antitumor agents: Growth inhibition, apoptosis induction and multidrug resistance reverting activity 125
Exploiting acylaminopyrazole scaffold for polypharmacology approach in Alzheimer's disease 124
The first dual ChE/FAAH inhibitors: new perspectives for Alzheimer's disease? 124
null 123
Extended Antimicrobial Profile of Chromone–Butenafine Hybrids 122
Nonsteroidal aromatase inhibitors for the treatment of breast cancer: an update. 122
Tackling Alzheimer's Disease with Existing Drugs:A Promising Strategy for Bypassing Obstacles 122
Modulation of Cytochromes P450 with Xanthone-Based Molecules: From Aromatase to Aldosterone Synthase and Steroid 11β-Hydroxylase Inhibition 121
Mono- or di-fluorinated analogues of Flavone-8-acetic acid: synthesis and in vitro biological activity 121
In vitro methods for characterizing new multi-potent compounds for Alzheimer’s disease 120
null 118
Small-molecule inhibitors/modulators of amyloid-β peptide aggregation and toxicity for the treatment of Alzheimer's disease: a patent review (2010 – 2012) 112
Prenylated Curcumin Analogues as Multipotent Tools to Tackle Alzheimer's Disease 110
Chromone-based small molecules for multistep shutdown of arachidonate pathway: Simultaneous inhibition of COX-2, 15-LOX and mPGES-1 enzymes 107
null 105
null 103
Quinone-Amino Acid Conjugates Targeting Leishmania Amino Acid Transporters 102
Boosting curcumin derivatives' cytotoxicity in cancer cells with light: An in vitro study 97
Recent progress on curcumin-based therapeutics: a patent review (2012-2016). Part I: Curcumin 92
Totale 16.893
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Categoria #
all - tutte 51.859
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 51.859
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021431 0 0 0 0 0 0 0 0 0 0 0 431
2021/20221.774 164 47 107 90 150 92 48 181 94 137 341 323
2022/20232.331 211 273 112 275 187 180 65 148 469 70 164 177
2023/2024745 40 99 38 89 54 212 47 42 14 35 38 37
2024/20252.604 103 366 264 135 535 128 220 76 53 184 142 398
2025/20266.785 727 548 564 456 678 335 603 308 1.294 546 428 298
Totale 19.083