CRIS Current Research Information System

BELLUTI, FEDERICA
 Distribuzione geografica
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Continente #
NA - Nord America 8.507
AS - Asia 6.429
EU - Europa 4.456
Continente sconosciuto - Info sul continente non disponibili 422
AF - Africa 372
SA - Sud America 303
OC - Oceania 12
Totale 20.501
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Nazione #
US - Stati Uniti d'America 8.316
VN - Vietnam 1.718
SG - Singapore 1.635
CN - Cina 1.587
IT - Italia 1.070
GB - Regno Unito 911
DE - Germania 588
HK - Hong Kong 391
SE - Svezia 362
IN - India 298
FR - Francia 253
UA - Ucraina 241
RU - Federazione Russa 233
BR - Brasile 196
NL - Olanda 161
BD - Bangladesh 149
IE - Irlanda 138
CA - Canada 133
JP - Giappone 129
CI - Costa d'Avorio 116
KR - Corea 113
FI - Finlandia 104
ZA - Sudafrica 99
JO - Giordania 97
TG - Togo 70
BG - Bulgaria 64
EE - Estonia 61
AR - Argentina 48
PH - Filippine 47
ES - Italia 44
ID - Indonesia 44
PL - Polonia 44
SC - Seychelles 35
CH - Svizzera 34
TR - Turchia 31
IR - Iran 30
PK - Pakistan 29
TH - Thailandia 29
MX - Messico 26
IQ - Iraq 25
AT - Austria 24
BE - Belgio 21
GR - Grecia 20
CZ - Repubblica Ceca 18
EC - Ecuador 17
HR - Croazia 17
EG - Egitto 15
CO - Colombia 14
MY - Malesia 13
TW - Taiwan 12
NG - Nigeria 11
SA - Arabia Saudita 11
LT - Lituania 9
AU - Australia 8
LB - Libano 8
VE - Venezuela 8
CL - Cile 7
JM - Giamaica 7
KE - Kenya 7
KZ - Kazakistan 7
HU - Ungheria 6
PT - Portogallo 6
RO - Romania 6
CR - Costa Rica 5
DZ - Algeria 5
GT - Guatemala 5
MD - Moldavia 5
PS - Palestinian Territory 5
PY - Paraguay 5
TN - Tunisia 5
AL - Albania 4
HN - Honduras 4
AE - Emirati Arabi Uniti 3
BO - Bolivia 3
BY - Bielorussia 3
ET - Etiopia 3
NZ - Nuova Zelanda 3
OM - Oman 3
RS - Serbia 3
UZ - Uzbekistan 3
A2 - ???statistics.table.value.countryCode.A2??? 2
AO - Angola 2
AZ - Azerbaigian 2
KW - Kuwait 2
LK - Sri Lanka 2
MA - Marocco 2
NI - Nicaragua 2
NO - Norvegia 2
NP - Nepal 2
PA - Panama 2
PE - Perù 2
UY - Uruguay 2
AM - Armenia 1
BA - Bosnia-Erzegovina 1
BB - Barbados 1
BS - Bahamas 1
CW - ???statistics.table.value.countryCode.CW??? 1
DO - Repubblica Dominicana 1
GH - Ghana 1
GI - Gibilterra 1
Totale 20.070
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Città #
Singapore 1.127
Ashburn 861
Southend 755
Fairfield 584
Chandler 560
San Jose 519
Santa Clara 400
Ho Chi Minh City 369
Hong Kong 368
Bologna 348
Hanoi 331
Woodbridge 308
Seattle 288
Wilmington 277
Houston 267
Hefei 237
Dong Ket 227
Cambridge 219
Council Bluffs 207
New York 202
Beijing 196
Ann Arbor 193
Princeton 188
Los Angeles 156
Jacksonville 155
Boardman 147
Dallas 139
Dublin 138
Abidjan 116
Tokyo 106
Seoul 97
Amman 96
Nanjing 85
Helsinki 83
Westminster 81
Lauterbourg 80
Buffalo 75
Lomé 70
Padova 68
Berlin 64
Sofia 64
Milan 54
Munich 54
Jinan 52
Bremen 50
Da Nang 50
San Diego 46
Shenyang 45
Chicago 44
Saint Petersburg 43
Orem 40
San Francisco 39
Atlanta 37
Phoenix 37
Redondo Beach 37
Montreal 36
Frankfurt am Main 35
Guangzhou 35
Redmond 35
Haiphong 34
Nanchang 32
Warsaw 32
Mülheim 31
Tianjin 31
Hebei 30
Jakarta 30
Denver 29
Shanghai 29
Bern 28
Toronto 28
London 26
Quận Bình Thạnh 26
São Paulo 26
Brooklyn 25
Bengaluru 24
Changsha 24
Dearborn 24
Zhengzhou 24
Biên Hòa 23
Jiaxing 23
Medford 22
Nuremberg 22
Boston 21
Hải Dương 21
Johannesburg 21
Olalla 20
Rimini 20
Brussels 19
Philadelphia 19
Rome 19
Des Moines 18
Mahé 18
Chennai 17
Redwood City 17
Can Tho 16
Sant Cugat del Vallès 16
Venezia 16
Boydton 15
Shenzhen 15
Thái Nguyên 15
Totale 12.566
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Nome #
Potent inhibition of human phosphodiesterase-5 by icariin derivatives 1.125
1,4-dihydropyridine derivatives as calcium channel modulators: the role of 3-methoxy-flavone moiety 355
Discovery of novel benzofuran-based compounds with neuroprotective and immunomodulatory properties for Alzheimer's disease treatment 345
Multitarget Strategy to Address Alzheimer's Disease: Design, Synthesis, Biological Evaluation, and Computational Studies of Coumarin-Based Derivatives 299
Cholinesterase inhibitors: xanthostigmine derivatives blocking the acetylcholinesterase-induced beta-amyloid aggregation. 256
Structure-Activity Relationships and Binding Mode in the Human Acetylcholinesterase Active Site of Pseudo-Irreversible Inhibitors Related to Xanthostigmine 255
Progettazione e sintesi di derivati benzofuranici per la malattia di Alzheimer 243
Chitosan nanoparticles for lipophilic anticancer drug delivery: Development, characterization and in vitro studies on HT29 cancer cells 240
Targeting neuronal calcium channels and GSK3β for Alzheimer's disease with naturally-inspired Diels-Alder adducts 233
Design, synthesis and biological profile of new inhibitors of multidrug resistance associated proteins carrying a polycyclic scaffold 229
Identification of chalcone-based antileishmanial agents targeting trypanothione reductase 226
Balanced dual acting compounds targeting aromatase and estrogen receptor α as an emerging therapeutic opportunity to counteract estrogen responsive breast cancer 223
Analogues of the dual acetylcholinesterase inhibitor AP2238: synthesis and SAR 222
Versatility of the Curcumin Scaffold: Discovery of Potent and Balanced Dual BACE-1 and GSK-3β Inhibitors 222
Benzophenones as xanthone-open model CYP11B1 inhibitors potentially useful for promoting wound healing 221
Exploiting the chalcone scaffold to develop multifunctional agents for Alzheimer’s disease 220
Fatty Acid Amide Hydrolase (FAAH), Acetylcholinesterase (AChE), and Butyrylcholinesterase (BuChE): Networked Targets for the Development of Carbamates as Potential Anti-Alzheimer's Disease Agents 217
Natural-like Chalcones with Antitumor Activity on Human MG63 Osteosarcoma Cells 215
Development of a Focused Library of Triazole-Linked Privileged-Structure-Based Conjugates Leading to the Discovery of Novel Phenotypic Hits against Protozoan Parasitic Infections 210
Identification of a new tamoxifen-xanthene hybrid as pro-apoptotic anticancer agent 210
Targeting the multifaceted neurotoxicity of Alzheimer's disease by tailored functionalisation of the curcumin scaffold 208
2-Arylbenzofuran-based molecules as multipotent Alzheimer's disease modifying agents 208
SAR and binding mode at the h-AChE active site of pseudo-irreversible inhibitors related to Xanthostigmine 202
Extensive SAR and computational studies of 3-{4-[(benzylmethylamino)methyl]phenyl}-6,7-dimethoxy-2H-2-chromenone (AP2238) derivatives. 200
Benzophenone-based derivatives: A novel series of potent and selective dual inhibitors of acetylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation 200
Interplay Between Endocannabinoid System and Neurodegeneration: Focus on Polypharmacology 199
Naturally inspired molecules as multifunctional agents for Alzheimer's disease treatment 199
Cardiovascular profile of xanthone-based 1,4 dihydropyridines bearing a lidoflazine pharmacophore fragment 194
Curcumin-1,2,3-triazole conjugation for targeting the cancer apoptosis machinery. 193
Novel Curcumin-Diethyl Fumarate Hybrid as a Dualistic GSK-3β Inhibitor/Nrf2 Inducer for the Treatment of Parkinson's Disease 192
Complementary medicinal chemistry-driven strategies toward new antitrypanosomal and antileishmanial lead drug candidates 190
CHOLINESTERASE INHIBITORS: SAR AND ENZYME INHIBITORY ACTIVITY OF 3-[omega-(BENZYLMETHYLAMINO)ALKOXY]XANTHEN-9-ONES 187
Enantioselective nonsteroidal aromatase inhibitors identified through a multidisciplinary medicinal chemistry approach 184
Single-digit nanomolar inhibitors lock the aromatase active site via a dualsteric targeting strategy 181
Chitosan nanoparticles for curcumin delivery: development, characterization and in-vitro studies on cancer cells 180
Potent inhibition of human phosphodiesterase-5 by icariin derivatives in an enzyme assay 179
New Coumarin derivatives as cholinergic and cannabinoid system modulators 176
Emerging targets in neurodegeneration: new opportunities for Alzheimer's disease treatment? 175
Nonsteroidal Aromatase inhibitors: synthesis and evaluation of new flavone derivatives 174
Lead optimization providing a series of flavone derivatives as potent nonsteroidal inhibitors of the cytochrome P450 aromatase enzyme 174
Polycyclic maleimide-based derivatives as first dual modulators of neuronal calcium channels and GSK-3β for Alzheimer's disease treatment 174
Homopterocarpanes as bridged triarylethylene analogues: synthesis and antagonistic effects in human MCF-7 breast cancer cells 173
Derivati a struttura benzofenonica come inibitori dell'acetilcolinesterasi 172
Multifaceted activity of polyciclic MDR revertant agents in drug-resistant leukemic cells: Role of the spacer 170
Multitarget Ligands in the Search for Novel Lead Candidates against Trypanosoma and Leishmania 169
Fluorinated benzophenone derivatives: balanced multipotent agents for Alzheimer's disease 169
Design, synthesis, and evaluation of benzophenone derivatives as novel acetylcholinesterase inhibitors 167
Multitarget Compounds for Bipolar Disorder: From Rational Design to Preliminary Pharmacokinetic Evaluation 167
Conjugation of Quinones with Natural Polyamines: Toward an Expanded Antitrypanosomatid Profile 165
Phenolic 1,3-diketones attenuate lipopolysaccharide-induced inflammatory response by an alternative magnesium-mediated mechanism 164
Imidazolylmethylbenzophenones as highly potent aromatase inhibitors. 163
Reconsidering Aromatase for Breast Cancer Treatment: New Roles for an Old Target 163
Multi-target-directed coumarin derivatives: hAChE and BAC1 inhibitors as potential anti-Alzheimer compounds 162
Naturally Inspired Coumarin Derivatives in Alzheimer’s Disease Drug Discovery: Latest Advances and Current Challenges 160
New derivatives of xanthenone-4-acetic acid: synthesis, pharmacological profile and effect on TNF-alpha and NO production by human immune cells 159
Switching from Aromatase Inhibitors to Dual Targeting Flavonoid-Based Compounds for Breast Cancer Treatment 157
In vitro studies of flavon-8-acetic acid analogues 157
Improved eradication efficacy of a combination of newly identified antimicrobial agents in C. albicans and S. aureus mixed-species biofilm 157
Studies on cytostatic and cytotoxic activity of new flavopiridol analogues 155
Hybrid drugs for Alzheimer's disease: new indanone derivatives bearing a pharmacophoric fragment of AP2238 155
Benzophenone derivatives as Inhibitors of Acetylcholinesterase 155
From AChE to BACE1 inhibitors: The role of the amine on the indanone scaffold 154
In vitro biological activity of new analogues of flavon-8-acetic acid 153
Flavonoid-inspired vascular disrupting agents: Exploring flavone-8-acetic acid and derivatives in the new century 153
Functionalization of the chalcone scaffold for the discovery of novel lead compounds targeting fungal infections 151
Toward the Development of Dual-Targeted Glyceraldehyde-3-phosphate Dehydrogenase/Trypanothione Reductase Inhibitors againstTrypanosoma bruceiandTrypanosoma cruzi 150
Polycyclic Maleimide-based Scaffold as New Privileged Structure for Navigating the Cannabinoid System Opportunities 149
Curcumin derivatives as beta-secretase (BACE1) inhibitors. 148
Multi-target strategy to address Alzheimer’s disease: Design, synthesis and biological evaluation of new tacrine-based dimers 147
Hitting drug-resistant malaria infection with triazole-linked flavonoid–chloroquine hybrid compounds 146
High-throughput screening of beta-secretase inhibitors by multiwell FRET assay 146
Design, Synthesis, and Biological and Crystallographic Evaluation of Novel Inhibitors ofPlasmodium falciparumEnoyl-ACP-reductase (PfFabI) 146
New potent P-glycoprotein inhibitors carrying a polycyclic scaffold 145
Targeting the Bacterial Membrane with a New Polycyclic Privileged Structure: A Powerful Tool To Face Staphylococcus aureus Infections 143
Exploiting acylaminopyrazole scaffold for polypharmacology approach in Alzheimer's disease 140
Design of Multifunctional Compounds for Cardiovascular Disease: From Natural Scaffolds to “Classical” Multitarget Approach 140
New potent inhibitors of cytochrome P450 aromatase 139
Targeting Alzheimer’s disease neurotoxicity by functionalization of the chalcone scaffold 137
Modulation of Amyloid β-induced Microglia Activation and Neuronal Cell Death by Curcumin and Analogues 136
Novel highly potent and selective nonsteroidal aromatase inhibitors: synthesis, biological evaluation and structure-activity relationships investigation 134
Extended Antimicrobial Profile of Chromone–Butenafine Hybrids 131
Chalcone-based carbamates for Alzheimer's disease treatment 131
Imidazolylmethylxanthones as potent inhibitors of cytochrome P450 aromatase 130
The first dual ChE/FAAH inhibitors: new perspectives for Alzheimer's disease? 128
Coumarin derivatives as potential antitumor agents: Growth inhibition, apoptosis induction and multidrug resistance reverting activity 128
Hybrid-Based Multi-Target Ligands for the Treatment of Alzheimer's Disease 127
Nonsteroidal aromatase inhibitors for the treatment of breast cancer: an update. 126
Tackling Alzheimer's Disease with Existing Drugs:A Promising Strategy for Bypassing Obstacles 125
In vitro methods for characterizing new multi-potent compounds for Alzheimer’s disease 124
Mono- or di-fluorinated analogues of Flavone-8-acetic acid: synthesis and in vitro biological activity 124
null 123
Chromone-based small molecules for multistep shutdown of arachidonate pathway: Simultaneous inhibition of COX-2, 15-LOX and mPGES-1 enzymes 123
Modulation of Cytochromes P450 with Xanthone-Based Molecules: From Aromatase to Aldosterone Synthase and Steroid 11β-Hydroxylase Inhibition 121
null 118
Small-molecule inhibitors/modulators of amyloid-β peptide aggregation and toxicity for the treatment of Alzheimer's disease: a patent review (2010 – 2012) 113
Prenylated Curcumin Analogues as Multipotent Tools to Tackle Alzheimer's Disease 113
Boosting curcumin derivatives' cytotoxicity in cancer cells with light: An in vitro study 110
Quinone-Amino Acid Conjugates Targeting Leishmania Amino Acid Transporters 105
null 105
null 103
Totale 18.159
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Categoria #
all - tutte 55.313
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 55.313
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.610 0 47 107 90 150 92 48 181 94 137 341 323
2022/20232.331 211 273 112 275 187 180 65 148 469 70 164 177
2023/2024745 40 99 38 89 54 212 47 42 14 35 38 37
2024/20252.604 103 366 264 135 535 128 220 76 53 184 142 398
2025/20266.817 727 548 564 456 678 335 603 308 1.294 546 428 330
2026/20271.386 927 459 0 0 0 0 0 0 0 0 0 0
Totale 20.501