CRIS Current Research Information System

RAMPA, ANGELA
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
NA - Nord America 6.933
AS - Asia 5.563
EU - Europa 3.674
Continente sconosciuto - Info sul continente non disponibili 319
AF - Africa 317
SA - Sud America 314
OC - Oceania 13
Totale 17.133
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 6.787
VN - Vietnam 1.496
SG - Singapore 1.449
CN - Cina 1.385
GB - Regno Unito 816
IT - Italia 724
DE - Germania 498
HK - Hong Kong 367
SE - Svezia 324
IN - India 253
UA - Ucraina 240
FR - Francia 216
RU - Federazione Russa 208
BR - Brasile 193
NL - Olanda 132
IE - Irlanda 126
CI - Costa d'Avorio 102
JO - Giordania 99
JP - Giappone 99
CA - Canada 92
ZA - Sudafrica 85
KR - Corea 83
FI - Finlandia 75
BD - Bangladesh 67
TG - Togo 59
EE - Estonia 56
BG - Bulgaria 55
AR - Argentina 46
PH - Filippine 45
ID - Indonesia 44
PL - Polonia 30
SC - Seychelles 30
CH - Svizzera 28
ES - Italia 26
EC - Ecuador 24
IR - Iran 23
TH - Thailandia 23
CO - Colombia 22
GR - Grecia 19
MX - Messico 19
PK - Pakistan 19
AT - Austria 18
TR - Turchia 18
IQ - Iraq 16
BE - Belgio 14
CZ - Repubblica Ceca 14
HR - Croazia 14
MY - Malesia 13
SA - Arabia Saudita 11
TW - Taiwan 11
AU - Australia 10
NG - Nigeria 10
VE - Venezuela 10
EG - Egitto 9
HN - Honduras 8
JM - Giamaica 8
KE - Kenya 7
LB - Libano 7
PT - Portogallo 7
CL - Cile 6
HU - Ungheria 6
LT - Lituania 6
GT - Guatemala 5
MD - Moldavia 5
OM - Oman 5
PS - Palestinian Territory 5
RO - Romania 5
KZ - Kazakistan 4
NP - Nepal 4
PE - Perù 4
PY - Paraguay 4
TN - Tunisia 4
AE - Emirati Arabi Uniti 3
ET - Etiopia 3
NI - Nicaragua 3
NZ - Nuova Zelanda 3
RS - Serbia 3
SV - El Salvador 3
UZ - Uzbekistan 3
A2 - ???statistics.table.value.countryCode.A2??? 2
AL - Albania 2
BO - Bolivia 2
BY - Bielorussia 2
CR - Costa Rica 2
DZ - Algeria 2
KG - Kirghizistan 2
KW - Kuwait 2
LK - Sri Lanka 2
MA - Marocco 2
NO - Norvegia 2
UY - Uruguay 2
AM - Armenia 1
AO - Angola 1
AZ - Azerbaigian 1
BA - Bosnia-Erzegovina 1
BB - Barbados 1
BN - Brunei Darussalam 1
CW - ???statistics.table.value.countryCode.CW??? 1
DO - Repubblica Dominicana 1
GH - Ghana 1
Totale 16.806
Salva come PNG Salva come JPEG
Città #
Singapore 963
Southend 706
Ashburn 664
Fairfield 532
Chandler 516
San Jose 415
Santa Clara 387
Hong Kong 346
Ho Chi Minh City 314
Woodbridge 297
Hanoi 271
Dong Ket 251
Wilmington 249
Houston 248
Bologna 241
Seattle 239
Council Bluffs 215
Cambridge 206
Beijing 196
Hefei 185
Princeton 170
Ann Arbor 162
Jacksonville 153
Boardman 139
New York 131
Dublin 125
Abidjan 101
Amman 99
Los Angeles 94
Tokyo 84
Nanjing 79
Westminster 75
Seoul 73
Lauterbourg 70
Dallas 67
Padova 64
Helsinki 61
Buffalo 59
Lomé 59
Sofia 55
Berlin 51
Jinan 49
Bremen 45
Da Nang 45
Munich 41
Shenyang 41
San Diego 39
Haiphong 37
Saint Petersburg 37
Milan 34
Redmond 31
Guangzhou 30
Redondo Beach 30
Tianjin 28
Mülheim 27
Nanchang 27
Chicago 26
Hebei 26
Frankfurt am Main 25
Jakarta 25
Phoenix 25
Quận Bình Thạnh 25
Shanghai 25
São Paulo 25
Orem 24
Bern 23
Changsha 23
Jiaxing 21
Warsaw 21
Bengaluru 20
Mahé 19
Medford 19
Zhengzhou 19
Dearborn 18
Biên Hòa 17
Brooklyn 17
Can Tho 17
Hải Dương 17
Johannesburg 17
Toronto 17
Boydton 16
Des Moines 16
Montreal 16
Nuremberg 16
Olalla 16
Venezia 16
Atlanta 15
London 15
Mountain View 15
Redwood City 15
Brussels 14
The Dalles 13
Hangzhou 12
San Francisco 12
Turin 12
Verona 12
Fremont 11
Kunming 11
Mexico City 11
Wuhan 11
Totale 10.739
Salva come PNG Salva come JPEG
Nome #
1,4-dihydropyridine derivatives as calcium channel modulators: the role of 3-methoxy-flavone moiety 357
Discovery of novel benzofuran-based compounds with neuroprotective and immunomodulatory properties for Alzheimer's disease treatment 355
Multitarget Strategy to Address Alzheimer's Disease: Design, Synthesis, Biological Evaluation, and Computational Studies of Coumarin-Based Derivatives 306
Benzofuran-Based Hybrid Compounds for the Inhibition of Cholinesterase Activity, Abeta Amyloid Aggregation, and Abeta Neurotoxicity 287
Cholinesterase inhibitors: xanthostigmine derivatives blocking the acetylcholinesterase-induced beta-amyloid aggregation. 261
Structure-Activity Relationships and Binding Mode in the Human Acetylcholinesterase Active Site of Pseudo-Irreversible Inhibitors Related to Xanthostigmine 259
Progettazione e sintesi di derivati benzofuranici per la malattia di Alzheimer 247
Targeting neuronal calcium channels and GSK3β for Alzheimer's disease with naturally-inspired Diels-Alder adducts 237
Design, synthesis and biological profile of new inhibitors of multidrug resistance associated proteins carrying a polycyclic scaffold 237
Identification of chalcone-based antileishmanial agents targeting trypanothione reductase 234
Analogues of the dual acetylcholinesterase inhibitor AP2238: synthesis and SAR 227
Versatility of the Curcumin Scaffold: Discovery of Potent and Balanced Dual BACE-1 and GSK-3β Inhibitors 226
Benzophenones as xanthone-open model CYP11B1 inhibitors potentially useful for promoting wound healing 226
Fatty Acid Amide Hydrolase (FAAH), Acetylcholinesterase (AChE), and Butyrylcholinesterase (BuChE): Networked Targets for the Development of Carbamates as Potential Anti-Alzheimer's Disease Agents 225
Balanced dual acting compounds targeting aromatase and estrogen receptor α as an emerging therapeutic opportunity to counteract estrogen responsive breast cancer 225
Exploiting the chalcone scaffold to develop multifunctional agents for Alzheimer’s disease 224
Identification of a new tamoxifen-xanthene hybrid as pro-apoptotic anticancer agent 219
2-Arylbenzofuran-based molecules as multipotent Alzheimer's disease modifying agents 209
SAR and binding mode at the h-AChE active site of pseudo-irreversible inhibitors related to Xanthostigmine 208
Extensive SAR and computational studies of 3-{4-[(benzylmethylamino)methyl]phenyl}-6,7-dimethoxy-2H-2-chromenone (AP2238) derivatives. 206
Naturally inspired molecules as multifunctional agents for Alzheimer's disease treatment 203
Interplay Between Endocannabinoid System and Neurodegeneration: Focus on Polypharmacology 202
Benzophenone-based derivatives: A novel series of potent and selective dual inhibitors of acetylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation 202
Curcumin-1,2,3-triazole conjugation for targeting the cancer apoptosis machinery. 200
Novel Curcumin-Diethyl Fumarate Hybrid as a Dualistic GSK-3β Inhibitor/Nrf2 Inducer for the Treatment of Parkinson's Disease 199
Cardiovascular profile of xanthone-based 1,4 dihydropyridines bearing a lidoflazine pharmacophore fragment 197
CHOLINESTERASE INHIBITORS: SAR AND ENZYME INHIBITORY ACTIVITY OF 3-[omega-(BENZYLMETHYLAMINO)ALKOXY]XANTHEN-9-ONES 190
Enantioselective nonsteroidal aromatase inhibitors identified through a multidisciplinary medicinal chemistry approach 185
From the dual function lead AP2238 to AP2469, a multi-target-directed ligand for the treatment of Alzheimer’s disease 184
Anthracene Based Compounds as New L-type Ca2+ Channel Blockers: Design, Synthesis, and Full Biological Profile 183
New Coumarin derivatives as cholinergic and cannabinoid system modulators 181
Nonsteroidal Aromatase inhibitors: synthesis and evaluation of new flavone derivatives 179
Homopterocarpanes as bridged triarylethylene analogues: synthesis and antagonistic effects in human MCF-7 breast cancer cells 178
Emerging targets in neurodegeneration: new opportunities for Alzheimer's disease treatment? 178
Lead optimization providing a series of flavone derivatives as potent nonsteroidal inhibitors of the cytochrome P450 aromatase enzyme 177
Polycyclic maleimide-based derivatives as first dual modulators of neuronal calcium channels and GSK-3β for Alzheimer's disease treatment 177
Derivati a struttura benzofenonica come inibitori dell'acetilcolinesterasi 176
Antitumor profile of new phenothiazine derivatives 173
Fluorinated benzophenone derivatives: balanced multipotent agents for Alzheimer's disease 173
Multifaceted activity of polyciclic MDR revertant agents in drug-resistant leukemic cells: Role of the spacer 171
Design, synthesis, and evaluation of benzophenone derivatives as novel acetylcholinesterase inhibitors 170
Targeting Alzheimer’s disease: Novel indanone hybrids bearing a pharmacophoric fragment of AP2238 169
Reconsidering Aromatase for Breast Cancer Treatment: New Roles for an Old Target 165
Multi-target-directed coumarin derivatives: hAChE and BAC1 inhibitors as potential anti-Alzheimer compounds 164
Phytoestrogens in postmenopause: the state of the art from a chemical, pharmacological and regulatory perspective 163
Naturally Inspired Coumarin Derivatives in Alzheimer’s Disease Drug Discovery: Latest Advances and Current Challenges 162
Switching from Aromatase Inhibitors to Dual Targeting Flavonoid-Based Compounds for Breast Cancer Treatment 162
New derivatives of xanthenone-4-acetic acid: synthesis, pharmacological profile and effect on TNF-alpha and NO production by human immune cells 162
In vitro studies of flavon-8-acetic acid analogues 161
Characterization of Cholinesterase inhibitors by means of immobilized enzyme reactor 161
Hybrid drugs for Alzheimer's disease: new indanone derivatives bearing a pharmacophoric fragment of AP2238 161
Benzophenone derivatives as Inhibitors of Acetylcholinesterase 159
Studies on cytostatic and cytotoxic activity of new flavopiridol analogues 158
Flavonoid-inspired vascular disrupting agents: Exploring flavone-8-acetic acid and derivatives in the new century 158
In vitro biological activity of new analogues of flavon-8-acetic acid 157
From AChE to BACE1 inhibitors: The role of the amine on the indanone scaffold 157
Functionalization of the chalcone scaffold for the discovery of novel lead compounds targeting fungal infections 154
High-throughput screening of beta-secretase inhibitors by multiwell FRET assay 153
Curcumin derivatives as beta-secretase (BACE1) inhibitors. 153
Polycyclic Maleimide-based Scaffold as New Privileged Structure for Navigating the Cannabinoid System Opportunities 153
Multi-target strategy to address Alzheimer’s disease: Design, synthesis and biological evaluation of new tacrine-based dimers 150
Hitting drug-resistant malaria infection with triazole-linked flavonoid–chloroquine hybrid compounds 148
Design, Synthesis, and Biological and Crystallographic Evaluation of Novel Inhibitors ofPlasmodium falciparumEnoyl-ACP-reductase (PfFabI) 148
Targeting the Bacterial Membrane with a New Polycyclic Privileged Structure: A Powerful Tool To Face Staphylococcus aureus Infections 148
New potent P-glycoprotein inhibitors carrying a polycyclic scaffold 145
New potent inhibitors of cytochrome P450 aromatase 143
Design of Multifunctional Compounds for Cardiovascular Disease: From Natural Scaffolds to “Classical” Multitarget Approach 142
The ability of coumarin-, flavanon- and flavonol-analogues of flavone acetic acid to stimulate human monocytes. 138
Novel highly potent and selective nonsteroidal aromatase inhibitors: synthesis, biological evaluation and structure-activity relationships investigation 137
Imidazolylmethylxanthones as potent inhibitors of cytochrome P450 aromatase 137
Chalcone-based carbamates for Alzheimer's disease treatment 136
Multidrug resistance reverting activity and antitumor profile of new phenothiazine derivatives 133
Coumarin derivatives as potential antitumor agents: Growth inhibition, apoptosis induction and multidrug resistance reverting activity 132
Hybrid-Based Multi-Target Ligands for the Treatment of Alzheimer's Disease 131
Nonsteroidal aromatase inhibitors for the treatment of breast cancer: an update. 130
The first dual ChE/FAAH inhibitors: new perspectives for Alzheimer's disease? 130
Mono- or di-fluorinated analogues of Flavone-8-acetic acid: synthesis and in vitro biological activity 129
Tackling Alzheimer's Disease with Existing Drugs:A Promising Strategy for Bypassing Obstacles 129
null 123
Modulation of Cytochromes P450 with Xanthone-Based Molecules: From Aromatase to Aldosterone Synthase and Steroid 11β-Hydroxylase Inhibition 122
Small-molecule inhibitors/modulators of amyloid-β peptide aggregation and toxicity for the treatment of Alzheimer's disease: a patent review (2010 – 2012) 119
null 118
null 105
Recent progress on curcumin-based therapeutics: a patent review (2012-2016). Part I: Curcumin 98
Recent progress on curcumin-based therapeutics: a patent review (2012-2016). Part II: curcumin derivatives in cancer and neurodegeneration 98
SAR of 9-amino-1,2,3-4-tetrahydroacridine-based acetylcholinesterase inhibitors: Synthesis, enzyme inhibitory activity, QSAR, and structure-based CoMFA of tacrine analogues 93
New approaches to the treatment of Alzheimer's disease. 91
null 82
3-(4-{[benzyl(methyl)amino]methyl}-phenyl)-6,7-dimethoxy-2H-2-chromenone (AP2238) inhibits both acetylcholinesterase and acetylcholinesterase-induced β-amyloid aggregation: A dual function lead for Alzheimer's disease therapy 81
null 79
Cardiovascular hybrid drugs: New benzazepinone derivatives as bradycardic agents endowed with selective β1-Non-competitive antagonism 77
Drifting of heme-coordinating group in imidazolylmethylxanthones leading to improved selective inhibition of CYP11B1 77
null 76
Targeting Steroidogenic Cytochromes P450 (CYPs) with 6-Substituted 1-Imidazolylmethylxanthones 71
Synthesis and antitumor activity of new derivatives of xanthen-9-one-4-acetic acid 70
null 70
Acetylcholinesterase inhibitors: SAR and kinetic studies on ω-[N-methyl-N-(3-alkylcarbamoyloxyphenyl]methyl] aminoalkoxyaryl derivatives 67
null 67
Synthesis and biological evaluation of 3-alkoxy analogues of flavone-8-acetic acid 63
Dual BACE-1/GSK-3β Inhibitors To Combat Alzheimer's Disease: A Focused Review 63
Totale 16.281
Salva come PNG Salva come JPEG
Categoria #
all - tutte 49.517
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 49.517
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.324 0 0 0 86 136 84 42 152 89 132 313 290
2022/20232.125 188 235 91 266 164 159 67 121 451 60 162 161
2023/2024592 37 84 35 67 52 172 32 32 10 22 23 26
2024/20252.267 68 339 244 104 520 116 176 52 53 160 94 341
2025/20265.408 647 451 521 385 595 282 506 186 1.015 396 229 195
2026/2027626 105 133 384 4 0 0 0 0 0 0 0 0
Totale 17.133