LOCATELLI, ALESSANDRA
 Distribuzione geografica
Continente #
NA - Nord America 5.083
AS - Asia 4.390
EU - Europa 3.719
AF - Africa 334
SA - Sud America 168
OC - Oceania 7
Continente sconosciuto - Info sul continente non disponibili 2
Totale 13.703
Nazione #
US - Stati Uniti d'America 5.007
CN - Cina 1.293
VN - Vietnam 1.132
SG - Singapore 1.102
IT - Italia 973
GB - Regno Unito 758
DE - Germania 432
SE - Svezia 314
IN - India 294
FR - Francia 239
HK - Hong Kong 204
UA - Ucraina 180
RU - Federazione Russa 170
NL - Olanda 157
IE - Irlanda 138
BR - Brasile 120
CI - Costa d'Avorio 105
TG - Togo 88
ZA - Sudafrica 74
JP - Giappone 72
KR - Corea 71
FI - Finlandia 70
EE - Estonia 56
CA - Canada 50
BG - Bulgaria 40
BE - Belgio 32
PH - Filippine 30
NG - Nigeria 27
CH - Svizzera 26
AT - Austria 22
JO - Giordania 22
SC - Seychelles 22
HR - Croazia 21
IR - Iran 21
AR - Argentina 20
TH - Thailandia 20
PK - Pakistan 19
IQ - Iraq 17
BD - Bangladesh 16
ID - Indonesia 15
PL - Polonia 15
GR - Grecia 13
MX - Messico 13
CZ - Repubblica Ceca 12
ES - Italia 12
TR - Turchia 12
TW - Taiwan 9
KZ - Kazakistan 8
LT - Lituania 7
RO - Romania 7
CO - Colombia 6
DZ - Algeria 6
LB - Libano 6
AU - Australia 5
CL - Cile 5
EC - Ecuador 5
PT - Portogallo 5
SA - Arabia Saudita 5
AE - Emirati Arabi Uniti 4
BA - Bosnia-Erzegovina 4
PY - Paraguay 4
BY - Bielorussia 3
DK - Danimarca 3
KE - Kenya 3
LU - Lussemburgo 3
MA - Marocco 3
TN - Tunisia 3
TT - Trinidad e Tobago 3
UZ - Uzbekistan 3
AL - Albania 2
BB - Barbados 2
BO - Bolivia 2
GT - Guatemala 2
MM - Myanmar 2
MY - Malesia 2
NZ - Nuova Zelanda 2
PE - Perù 2
UY - Uruguay 2
VE - Venezuela 2
A1 - Anonimo 1
AF - Afghanistan, Repubblica islamica di 1
AM - Armenia 1
BZ - Belize 1
CR - Costa Rica 1
EG - Egitto 1
GD - Grenada 1
GI - Gibilterra 1
IL - Israele 1
JM - Giamaica 1
KW - Kuwait 1
LA - Repubblica Popolare Democratica del Laos 1
MD - Moldavia 1
NI - Nicaragua 1
NO - Norvegia 1
NP - Nepal 1
OM - Oman 1
PA - Panama 1
PS - Palestinian Territory 1
RS - Serbia 1
SI - Slovenia 1
Totale 13.697
Città #
Singapore 737
Southend 643
Ashburn 573
Fairfield 443
Chandler 441
Bologna 363
Dong Ket 325
San Jose 294
Woodbridge 236
Ann Arbor 225
Wilmington 219
Santa Clara 199
Ho Chi Minh City 198
Hong Kong 193
Seattle 187
Houston 183
Cambridge 169
Hefei 168
Hanoi 157
Princeton 155
Beijing 139
Dublin 136
Jacksonville 116
Abidjan 105
Boardman 101
New York 98
Lomé 88
Lauterbourg 77
Nanjing 77
Hyderabad 75
Westminster 69
Padova 67
Helsinki 60
Tokyo 60
Los Angeles 58
Milan 57
Seoul 57
Bremen 55
Berlin 53
Dallas 51
Guangzhou 41
Changsha 39
Jinan 39
Sofia 39
Buffalo 37
Shenyang 36
Saint Petersburg 35
Shanghai 35
Da Nang 31
Redwood City 30
Brussels 29
Council Bluffs 28
Haiphong 27
Redondo Beach 27
Abeokuta 26
Frankfurt am Main 26
Hebei 24
Tianjin 24
Toronto 24
London 23
Medford 23
Munich 23
Nanchang 23
Amman 22
Dearborn 20
Mülheim 20
Bern 19
Leawood 18
San Diego 18
Zhengzhou 18
Orem 17
Fremont 16
The Dalles 16
Mahé 15
Verona 15
Jiaxing 14
Johannesburg 14
Napoli 14
Phoenix 14
Rome 14
Wuhan 14
Caserta 13
Bengaluru 12
Cesena 12
Des Moines 12
San Francisco 12
Taizhou 12
Chennai 11
Nuremberg 11
Pune 11
Redmond 11
Salerno 11
Vienna 11
Bures-sur-Yvette 10
Bắc Giang 10
Can Tho 10
Hải Dương 10
São Paulo 10
Taiyuan 10
Düsseldorf 9
Totale 8.902
Nome #
Balancing Affinity, Selectivity, and Cytotoxicity of Hydrazone-Based G-Quadruplex Ligands for Activation of Interferon β Genes in Cancer Cells 286
4-Imidazo[2,1-b]thiazole-1,4-DHPs and neuroprotection: preliminary study in hits searching 246
Synthesis, in vitro and in vivo biological evaluation of substituted 3-(5-imidazo[2,1-b]thiazolylmethylene)-2-indolinones as new potent anticancer agents 244
Antitumor activity and COMPARE analysis of bis-indole derivatives 241
Ligand Based Approach to L-Type Calcium Channel by Imidazo[2,1-b]thiazole-1,4-Dihydropyridines: from Heart Activity to Brain Affinity 241
Toward the Development of Specific G‑Quadruplex Binders: Synthesis, Biophysical, and Biological Studies of New Hydrazone Derivatives 229
2-[(E)-3-(6-chloroimidazo[2,1-b]thiazol-5-ylprop-2-enyl]5,6-dimethoxy-3-methyl-1,4-benzo quinone: a new inhibitor of NADH dehydrogenase with antitumor activity 228
Antitumor Activity of New Substituted 3-(5-Imidazo[2,1-b]thiazolylmethylene)-2-indolinones and 3-(5-Imidazo[2,1-b]thiadiazolylmethylene)-2-indolinones: Selectivity Against Colon Tumor Cells and Effect on Cell Cycle-Related Events. 228
Indole derivative interacts with estrogen receptor beta and inhibits human ovarian cancer cell growth 228
P53-dependent and p53-independent anticancer activity of a new indole derivative in human osteosarcoma cells 224
Chemopreventive and antioxidant activity of 6-substituted imidazo [2,1-b]thiazoles 221
Bis-guanylhydrazone diimidazo[1,2-a:1,2-c]pyrimidine as a novel and specific G-quadruplex binding motif 220
Antitumor Activity of Bis-indole Derivatives 219
Diphenidol-related diamines as novel muscarinic M4 receptor antagonists 217
Antitumor Activity of Substituted E-3-(3,4,5-Trimethoxybenzylidene)-1,3-dihydroindol-2-ones 215
SUBSTITUTED E-3-(3-INDOLYLMETHYLENE)1,3-DIHYDROINDOL-2-ONES WITH ANTITUMOR ACTIVITY. IN-DEPTH STUDY OF THE EFFECT ON GROWTH OF BREAST CANCER CELLS. 212
2-Indolinone a versatile scaffold for treatment of cancer: A patent review (2008-2014) 212
Investigation on the effects of antimicrobial imidazo[2,1-b]thiazole derivatives on the genitourinary microflora 211
Monohydrazone Based G-Quadruplex Selective Ligands Induce DNA Damage and Genome Instability in Human Cancer Cells 209
Composti organici ad attività antitumorale 205
Synthesis of 3-(Imidazo[2,1-b]thiazol-6-yl)-2H-chromen-2-one derivatives and study of their antiviral activity against parvovirus B19 201
Substituted E-3-(3-Indolylmethylene)-1,3-dihydroindol-2-ones with Antitumor Activity. In Depth Study of the Effect on Growth of Breast Cancer Cells 199
Chemiluminescent high-throughput microassay applied to imidazo[2,1-b]thiazole derivatives as potential acetylcholinesterase and butyrylcholinesterase inhibitors 198
New isatin derivatives with antioxidant activity 196
Imidazo[2,1-b]thiazole guanylhydrazones as RSK2 inhibitors 196
New Antitumor Imidazo[2,1-b]thiazole Guanylhydrazones and Analogues 193
Antitumor Activity of New Substituted 3-(5-Imidazo[2,1-b]thiazolylmethylene)-2-indolinones and Study of Their Effect on the Cell Cycle 192
Antitumor activity of imidazo[2,1-b]thiazole guanylhydrazones and analogs. 191
Synthesis, in vitro cytotoxicity, molecular docking and ADME study of some indolin-2-one linked 1,2,3-triazole derivatives 191
Imidazo[2,1-b]thiazole System: a Scaffold Endowing Dihydropyridines With Selective Cardiodepressant Activity 188
Dansyl acetyl trehalose: a novel tool to investigate the cellular fate of trehalose 188
Intracellular magnesium content decreases during mitochondria-mediated apoptosis induced by a new indole-derivative in human colon cancer cells 186
Isatin Bis-Imidathiazole Hybrids Identified as FtsZ Inhibitors with On-Target Activity Against Staphylococcus aureus 185
Identification of a new bisindolinone arresting IGROV1 cells proliferation 184
Substituted E-3-(2-chloro-3-indolylmethylene)1,3-dihydroindol-2-ones with antitumor activity 184
Substituted E-3-(2-chloro-3-indolylmethylene)1,3-dihydroindol-2-ones with antitumor activity. Effect on the cell cycle and apoptosis. 183
Nuovi derivati 4-imidazo[2,1-b]tiazoli-4-diidropiridinici quali selettivi calciomodulatori cardiaci 182
p53-dependent and p53-independent anticancer activity of a new indole derivative in human osteosarcoma cells 181
N-Benzyl-2-chloroindole-3-carboxylic acids as potential anti-inflammatory agents. Synthesis and screening for the effects on human neutrophil functions and on COX1/COX2 activity 179
A Patent Review on Thiazole Derivatives (2008-2013) 179
Antitumor activity of compounds bearing the new heterocyclic system thiazolo[2',3':2,3]imidazo[4,5-c]quinoline 178
Attività calcio modulatrice a livello cardiaco e vasale di derivati imidazo[2,1-b]tiazolici 178
Bis-indole derivatives with antitumor activity turn out to be specific ligands of human telomeric G-quadruplex. 175
Small-Molecules Targeting Sirtuin 1: A Patent Review (2012-2015) 175
Benzoindol-2-one derivatives inducing mitochondria-mediated apoptosis associated with magnesium content decrease 173
Imidazo[2,1-b] Thiazole: Introduction, Current and Perspective 170
Cytotoxic activities of substituted 3-(3,4,5-trimethoxybenzylidene)- 1,3-dihydroindol-2-ones and studies on their mechanisms of action 168
Potential Antitumor Agents. 37. Synthesis and Antitumor Activity of Guanylhydrazones from Imidazo[2,1-b]thiazoles and from the New Heterocyclic System Thiazolo[2',3':2,3]imidazo[4,5-c]quinoline 167
Attività antitumorale di nuovi 3-(5-imidazo[2,1-b]tiazolilmetilen)-2-indolinoni sostituiti e studio del loro effetto sul ciclo cellulare 163
Substituted 3-(5-imidazo[2,1-b]thiazolylmethylene)-2-indolinones and analogues: synthesis, citotoxic activity, and study of the mechanism of action. 161
Targeting human telomeric and promoter G-quardruplexes: synthesis, biophysical and biological studies of new guanylhydrazones as potential antitumor agents 161
Diethyl 4-(6-Chloroimidazo[2,1-b]thiazol-5-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate and Ethyl 4-(6-Chloroimidazo[2,1-b]thiazol-5-yl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate 160
Substituted E-3-(3-indolylmethylene)1,3-dihydroindol-2-ones with antiproliferative activity. Study of the effects on HL-60 leukemia cells 160
Synthesis and antitumor activity of Guanylhydrazones from 6-(2,4-dichloro-5-nitrophenyl)imidazo[2,1-b]thiazoles and 6-pyridylimidazo[2,1-b]thiazoles 158
New substituted E-3-(2-Chloro-3-indolylmethylene)1,3-dihydroindol-2-ones with antitumor activity 157
Substituted (E)-3-(2-chloro-3-indolylmethylene)-1,3-dihydroindol-2-ones as antitumor agents: SARs and study of the mechanism of action 157
Sintesi e attività antitumorale di guanilidrazoni derivati dal nucleo imidazo[2,1-b]tiazolico e dal nuovo sistema eterociclico tiazolo[2',3':2,3]imidazo[4,5-c]chinolina 154
Synthesis and chemiluminescent high throughput microassay for inhibition of acetylcholinesterase and butyrylcholinesterase activity by imidazo[2,1-b]thiazole derivatives 151
Recent Patents on Thiazole Derivatives Endowed with Antitumor Activity 151
Synthesis and antitumor activity of guanylhydrazones from 6-(2,4-dichloro-5-nitrophenyl)- and 6-pyridyl-imidazo[2,1-b]thiazoles. 149
Synthesis and chemiluminescent high throughput screening for inhibition of acetylcholinesterase activity by imidazo[2,1-b]thiazole derivatives 149
Antitumor activity of bis-indolinone derivatives. 149
Novel thiazole derivatives: a patent review (2008 – 2012; Part 1) 147
Isatin Bis-Indole and Bis-Imidazothiazole Hybrids: Synthesis and Antimicrobial Activity 146
Identification of a new benzoindol-2-one derivative as a potential modulator of p53 pathway in cancer cells 146
Toward the development of specific G-quadruplex binders: biophysical studies of new hydrazone derivatives. 146
Synthesis and biological evaluation of thiazole derivatives on basic defects underlying cystic fibrosis. 144
Synthesis and biological evaluation of new bis-indolinone derivatives endowed with cytotoxic activity 137
Effect of new ubiquinone-imidazo[2,1-b] thiazoles on mitochondrial Complex I (NADH ubiquinone reductase) and on mitochondrial permeability transition pore. 131
Novel thiazole derivatives: a patent review (2008-2012. Part.2) 128
Cystic Fibrosis: a New Target for 4-Imidazo[2,1-b]thiazole-1,4- Dihydropyridines. 128
Synthesis and antiproliferative activity of imidazo[2,1-b][1,3,4]thiadiazole derivatives 122
SYNTHESIS OF 3-(5-IMIDAZO[2,1-b]THIAZOLYLMETHYLENE)-2-INDOLINONES INHIBITING TUBULIN ASSEMBLY AND INDUCING APOPTOSIS IN HT-29 COLON CANCER CELLS 116
Sintesi di derivati imidazo[2,1-b]tiazolici e valutazioone dell'attività inibitoria dell'acetilcolinesterasi mediante un metodo HTS chemiluminescente 112
IDENTIFICATION OF A NEW POTENTIAL LIGAND OF THE ESTROGEN RECEPTOR BETA, INHIBITING HUMAN OVARIAN CANCER CELL GROWTH 96
Potential antitumor agents. 34.(1)Synthesis and antitumor activity of guanylhydrazones from imidazo[2,1-b]thiazoles and from diimidazo[1,2-a:1,2-c]pyrimidine 84
Small-Molecules Targeting Kinases Involved in Pulmonary Hypertension: a Patent Review (2010-2015) 82
null 72
Repurposing 1,4-Dihydropyridine Scaffold: 4-Imidazo[2,1-b]thiazole-Derivatives from Calcium Entry Blockers to a New Approach for Gut Dysfunctional Motility 65
Molecular Tools for Precision Targeting and Detection of G-Quadruplex Structures 56
Identification of MBT3T as a new effective therapeutic option in imatinib-resistant gastrointestinal stromal tumors (GISTs) 12
Totale 13.946
Categoria #
all - tutte 35.241
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 35.241


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021573 0 0 0 0 0 0 0 0 0 0 76 497
2021/20221.480 196 46 72 75 147 95 45 120 61 84 289 250
2022/20231.711 147 291 100 282 120 124 46 104 274 40 120 63
2023/2024585 43 79 29 48 41 176 47 31 10 34 18 29
2024/20252.008 132 274 192 133 314 91 274 64 10 204 87 233
2025/20264.066 367 421 337 353 517 250 409 117 802 361 132 0
Totale 13.946