LOCATELLI, ALESSANDRA
 Distribuzione geografica
Continente #
NA - Nord America 3.681
EU - Europa 2.872
AS - Asia 1.407
AF - Africa 214
SA - Sud America 8
OC - Oceania 4
Continente sconosciuto - Info sul continente non disponibili 1
Totale 8.187
Nazione #
US - Stati Uniti d'America 3.664
IT - Italia 732
GB - Regno Unito 717
VN - Vietnam 446
CN - Cina 396
DE - Germania 357
SE - Svezia 308
IN - India 248
SG - Singapore 236
UA - Ucraina 176
IE - Irlanda 132
FR - Francia 122
RU - Federazione Russa 100
TG - Togo 88
ZA - Sudafrica 57
EE - Estonia 56
BG - Bulgaria 39
CI - Costa d'Avorio 27
CH - Svizzera 26
NG - Nigeria 26
BE - Belgio 25
JO - Giordania 21
HR - Croazia 20
IR - Iran 19
CA - Canada 16
SC - Seychelles 15
FI - Finlandia 13
CZ - Repubblica Ceca 10
GR - Grecia 10
JP - Giappone 8
PL - Polonia 7
TR - Turchia 7
PK - Pakistan 6
LB - Libano 5
RO - Romania 5
AU - Australia 4
BR - Brasile 4
ES - Italia 4
AT - Austria 3
DK - Danimarca 3
ID - Indonesia 3
NL - Olanda 3
AR - Argentina 2
CL - Cile 2
IQ - Iraq 2
KZ - Kazakistan 2
TW - Taiwan 2
A1 - Anonimo 1
AE - Emirati Arabi Uniti 1
BA - Bosnia-Erzegovina 1
BD - Bangladesh 1
HK - Hong Kong 1
IL - Israele 1
JM - Giamaica 1
KR - Corea 1
MD - Moldavia 1
NO - Norvegia 1
PT - Portogallo 1
SN - Senegal 1
TJ - Tagikistan 1
Totale 8.187
Città #
Southend 643
Fairfield 443
Chandler 441
Dong Ket 325
Ashburn 287
Woodbridge 236
Bologna 226
Ann Arbor 225
Wilmington 219
Singapore 206
Seattle 186
Houston 180
Cambridge 169
Princeton 155
Dublin 131
Jacksonville 115
Lomé 88
New York 77
Hyderabad 74
Nanjing 71
Westminster 69
Padova 67
Bremen 55
Berlin 53
Sofia 39
Santa Clara 38
Jinan 35
Saint Petersburg 35
Shenyang 32
Redwood City 30
Beijing 29
Abidjan 27
Milan 27
Abeokuta 26
Changsha 24
Hebei 24
Brussels 23
Medford 23
Nanchang 23
Boardman 22
Amman 21
Dearborn 20
Mülheim 20
Bern 19
Tianjin 19
Leawood 18
San Diego 17
Mahé 15
Fremont 14
Los Angeles 14
Napoli 14
Caserta 13
Jiaxing 13
Toronto 13
Des Moines 12
Helsinki 12
Pune 11
Redmond 11
Salerno 11
Zhengzhou 11
Guangzhou 10
Falls Church 9
Monmouth Junction 9
Taizhou 9
Bühl 8
Moncalieri 8
Norwalk 8
Shanghai 8
Turin 8
Albissola Marina 7
Cesena 7
Kunming 7
Lanzhou 7
London 7
Ningbo 7
Olalla 7
Rome 7
Taiyuan 7
Tokyo 7
Verona 7
Boydton 6
Haikou 6
Hangzhou 6
Istanbul 6
Mountain View 6
Phoenix 6
Ardabil 5
Bangalore 5
Frankfurt Am Main 5
Hradec Králové 5
New Delhi 5
Parma 5
Scafati 5
Altamura 4
Andover 4
Cergy 4
Forlì 4
Katowice 4
Lentini 4
Naples 4
Totale 5.749
Nome #
Antitumor activity and COMPARE analysis of bis-indole derivatives 182
2-[(E)-3-(6-chloroimidazo[2,1-b]thiazol-5-ylprop-2-enyl]5,6-dimethoxy-3-methyl-1,4-benzo quinone: a new inhibitor of NADH dehydrogenase with antitumor activity 164
Antitumor Activity of New Substituted 3-(5-Imidazo[2,1-b]thiazolylmethylene)-2-indolinones and 3-(5-Imidazo[2,1-b]thiadiazolylmethylene)-2-indolinones: Selectivity Against Colon Tumor Cells and Effect on Cell Cycle-Related Events. 159
Synthesis, in vitro and in vivo biological evaluation of substituted 3-(5-imidazo[2,1-b]thiazolylmethylene)-2-indolinones as new potent anticancer agents 158
Chemopreventive and antioxidant activity of 6-substituted imidazo [2,1-b]thiazoles 157
Antitumor Activity of New Substituted 3-(5-Imidazo[2,1-b]thiazolylmethylene)-2-indolinones and Study of Their Effect on the Cell Cycle 156
P53-dependent and p53-independent anticancer activity of a new indole derivative in human osteosarcoma cells 156
Ligand Based Approach to L-Type Calcium Channel by Imidazo[2,1-b]thiazole-1,4-Dihydropyridines: from Heart Activity to Brain Affinity 152
2-Indolinone a versatile scaffold for treatment of cancer: A patent review (2008-2014) 152
Antitumor Activity of Bis-indole Derivatives 150
Antitumor Activity of Substituted E-3-(3,4,5-Trimethoxybenzylidene)-1,3-dihydroindol-2-ones 149
4-Imidazo[2,1-b]thiazole-1,4-DHPs and neuroprotection: preliminary study in hits searching 148
Synthesis of 3-(Imidazo[2,1-b]thiazol-6-yl)-2H-chromen-2-one derivatives and study of their antiviral activity against parvovirus B19 142
Indole derivative interacts with estrogen receptor beta and inhibits human ovarian cancer cell growth 141
Bis-guanylhydrazone diimidazo[1,2-a:1,2-c]pyrimidine as a novel and specific G-quadruplex binding motif 141
Diphenidol-related diamines as novel muscarinic M4 receptor antagonists 140
SUBSTITUTED E-3-(3-INDOLYLMETHYLENE)1,3-DIHYDROINDOL-2-ONES WITH ANTITUMOR ACTIVITY. IN-DEPTH STUDY OF THE EFFECT ON GROWTH OF BREAST CANCER CELLS. 140
N-Benzyl-2-chloroindole-3-carboxylic acids as potential anti-inflammatory agents. Synthesis and screening for the effects on human neutrophil functions and on COX1/COX2 activity 138
Composti organici ad attività antitumorale 135
Chemiluminescent high-throughput microassay applied to imidazo[2,1-b]thiazole derivatives as potential acetylcholinesterase and butyrylcholinesterase inhibitors 134
Toward the Development of Specific G‑Quadruplex Binders: Synthesis, Biophysical, and Biological Studies of New Hydrazone Derivatives 133
Substituted E-3-(3-Indolylmethylene)-1,3-dihydroindol-2-ones with Antitumor Activity. In Depth Study of the Effect on Growth of Breast Cancer Cells 132
Antitumor activity of imidazo[2,1-b]thiazole guanylhydrazones and analogs. 132
New Antitumor Imidazo[2,1-b]thiazole Guanylhydrazones and Analogues 129
Investigation on the effects of antimicrobial imidazo[2,1-b]thiazole derivatives on the genitourinary microflora 128
Substituted E-3-(2-chloro-3-indolylmethylene)1,3-dihydroindol-2-ones with antitumor activity 127
Substituted E-3-(2-chloro-3-indolylmethylene)1,3-dihydroindol-2-ones with antitumor activity. Effect on the cell cycle and apoptosis. 125
Bis-indole derivatives with antitumor activity turn out to be specific ligands of human telomeric G-quadruplex. 125
Attività antitumorale di nuovi 3-(5-imidazo[2,1-b]tiazolilmetilen)-2-indolinoni sostituiti e studio del loro effetto sul ciclo cellulare 125
Antitumor activity of compounds bearing the new heterocyclic system thiazolo[2',3':2,3]imidazo[4,5-c]quinoline 124
New isatin derivatives with antioxidant activity 123
Attività calcio modulatrice a livello cardiaco e vasale di derivati imidazo[2,1-b]tiazolici 121
Balancing Affinity, Selectivity, and Cytotoxicity of Hydrazone-Based G-Quadruplex Ligands for Activation of Interferon β Genes in Cancer Cells 120
p53-dependent and p53-independent anticancer activity of a new indole derivative in human osteosarcoma cells 118
Monohydrazone Based G-Quadruplex Selective Ligands Induce DNA Damage and Genome Instability in Human Cancer Cells 118
Potential Antitumor Agents. 37. Synthesis and Antitumor Activity of Guanylhydrazones from Imidazo[2,1-b]thiazoles and from the New Heterocyclic System Thiazolo[2',3':2,3]imidazo[4,5-c]quinoline 117
Nuovi derivati 4-imidazo[2,1-b]tiazoli-4-diidropiridinici quali selettivi calciomodulatori cardiaci 116
Benzoindol-2-one derivatives inducing mitochondria-mediated apoptosis associated with magnesium content decrease 112
Imidazo[2,1-b]thiazole guanylhydrazones as RSK2 inhibitors 112
Synthesis and antitumor activity of Guanylhydrazones from 6-(2,4-dichloro-5-nitrophenyl)imidazo[2,1-b]thiazoles and 6-pyridylimidazo[2,1-b]thiazoles 112
Imidazo[2,1-b]thiazole System: a Scaffold Endowing Dihydropyridines With Selective Cardiodepressant Activity 109
Small-Molecules Targeting Sirtuin 1: A Patent Review (2012-2015) 108
Intracellular magnesium content decreases during mitochondria-mediated apoptosis induced by a new indole-derivative in human colon cancer cells 107
Imidazo[2,1-b] Thiazole: Introduction, Current and Perspective 106
Diethyl 4-(6-Chloroimidazo[2,1-b]thiazol-5-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate and Ethyl 4-(6-Chloroimidazo[2,1-b]thiazol-5-yl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate 105
Substituted E-3-(3-indolylmethylene)1,3-dihydroindol-2-ones with antiproliferative activity. Study of the effects on HL-60 leukemia cells 104
Dansyl acetyl trehalose: a novel tool to investigate the cellular fate of trehalose 104
A Patent Review on Thiazole Derivatives (2008-2013) 102
Sintesi e attività antitumorale di guanilidrazoni derivati dal nucleo imidazo[2,1-b]tiazolico e dal nuovo sistema eterociclico tiazolo[2',3':2,3]imidazo[4,5-c]chinolina 101
Recent Patents on Thiazole Derivatives Endowed with Antitumor Activity 99
Cytotoxic activities of substituted 3-(3,4,5-trimethoxybenzylidene)- 1,3-dihydroindol-2-ones and studies on their mechanisms of action 98
Synthesis and chemiluminescent high throughput screening for inhibition of acetylcholinesterase activity by imidazo[2,1-b]thiazole derivatives 96
Substituted (E)-3-(2-chloro-3-indolylmethylene)-1,3-dihydroindol-2-ones as antitumor agents: SARs and study of the mechanism of action 92
Synthesis and antitumor activity of guanylhydrazones from 6-(2,4-dichloro-5-nitrophenyl)- and 6-pyridyl-imidazo[2,1-b]thiazoles. 89
Antitumor activity of bis-indolinone derivatives. 87
Novel thiazole derivatives: a patent review (2008 – 2012; Part 1) 87
Substituted 3-(5-imidazo[2,1-b]thiazolylmethylene)-2-indolinones and analogues: synthesis, citotoxic activity, and study of the mechanism of action. 86
New substituted E-3-(2-Chloro-3-indolylmethylene)1,3-dihydroindol-2-ones with antitumor activity 85
Targeting human telomeric and promoter G-quardruplexes: synthesis, biophysical and biological studies of new guanylhydrazones as potential antitumor agents 84
Synthesis, in vitro cytotoxicity, molecular docking and ADME study of some indolin-2-one linked 1,2,3-triazole derivatives 84
Cystic Fibrosis: a New Target for 4-Imidazo[2,1-b]thiazole-1,4- Dihydropyridines. 82
Identification of a new benzoindol-2-one derivative as a potential modulator of p53 pathway in cancer cells 79
Novel thiazole derivatives: a patent review (2008-2012. Part.2) 78
Effect of new ubiquinone-imidazo[2,1-b] thiazoles on mitochondrial Complex I (NADH ubiquinone reductase) and on mitochondrial permeability transition pore. 77
Synthesis and chemiluminescent high throughput microassay for inhibition of acetylcholinesterase and butyrylcholinesterase activity by imidazo[2,1-b]thiazole derivatives 76
Synthesis and antiproliferative activity of imidazo[2,1-b][1,3,4]thiadiazole derivatives 73
Toward the development of specific G-quadruplex binders: biophysical studies of new hydrazone derivatives. 73
null 72
Synthesis and biological evaluation of thiazole derivatives on basic defects underlying cystic fibrosis. 68
IDENTIFICATION OF A NEW POTENTIAL LIGAND OF THE ESTROGEN RECEPTOR BETA, INHIBITING HUMAN OVARIAN CANCER CELL GROWTH 59
Sintesi di derivati imidazo[2,1-b]tiazolici e valutazioone dell'attività inibitoria dell'acetilcolinesterasi mediante un metodo HTS chemiluminescente 56
SYNTHESIS OF 3-(5-IMIDAZO[2,1-b]THIAZOLYLMETHYLENE)-2-INDOLINONES INHIBITING TUBULIN ASSEMBLY AND INDUCING APOPTOSIS IN HT-29 COLON CANCER CELLS 53
Potential antitumor agents. 34.(1)Synthesis and antitumor activity of guanylhydrazones from imidazo[2,1-b]thiazoles and from diimidazo[1,2-a:1,2-c]pyrimidine 53
Synthesis and biological evaluation of new bis-indolinone derivatives endowed with cytotoxic activity 49
Isatin Bis-Indole and Bis-Imidazothiazole Hybrids: Synthesis and Antimicrobial Activity 33
Small-Molecules Targeting Kinases Involved in Pulmonary Hypertension: a Patent Review (2010-2015) 23
Identification of a new bisindolinone arresting IGROV1 cells proliferation 6
Totale 8.386
Categoria #
all - tutte 20.080
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 20.080


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201.604 0 0 34 109 208 187 241 269 254 136 64 102
2020/20211.416 207 82 27 53 31 152 40 66 98 87 76 497
2021/20221.480 196 46 72 75 147 95 45 120 61 84 289 250
2022/20231.711 147 291 100 282 120 124 46 104 274 40 120 63
2023/2024585 43 79 29 48 41 176 47 31 10 34 18 29
2024/2025514 132 274 108 0 0 0 0 0 0 0 0 0
Totale 8.386