CRIS Current Research Information System

LOCATELLI, ALESSANDRA
 Distribuzione geografica
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Continente #
NA - Nord America 4.514
EU - Europa 3.460
AS - Asia 3.412
AF - Africa 323
SA - Sud America 144
OC - Oceania 5
Continente sconosciuto - Info sul continente non disponibili 1
Totale 11.859
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Nazione #
US - Stati Uniti d'America 4.461
CN - Cina 1.163
SG - Singapore 1.001
IT - Italia 883
GB - Regno Unito 744
VN - Vietnam 579
DE - Germania 427
SE - Svezia 314
IN - India 269
HK - Hong Kong 188
UA - Ucraina 178
RU - Federazione Russa 170
FR - Francia 163
NL - Olanda 147
IE - Irlanda 133
BR - Brasile 105
CI - Costa d'Avorio 105
TG - Togo 88
ZA - Sudafrica 66
KR - Corea 57
EE - Estonia 56
JP - Giappone 48
BG - Bulgaria 39
CA - Canada 39
FI - Finlandia 33
BE - Belgio 31
NG - Nigeria 27
CH - Svizzera 26
SC - Seychelles 22
IR - Iran 21
JO - Giordania 21
AT - Austria 20
HR - Croazia 20
AR - Argentina 18
PL - Polonia 14
ID - Indonesia 12
CZ - Repubblica Ceca 11
PK - Pakistan 11
ES - Italia 10
GR - Grecia 10
MX - Messico 9
TR - Turchia 9
LT - Lituania 6
AU - Australia 5
BD - Bangladesh 5
CO - Colombia 5
DZ - Algeria 5
EC - Ecuador 5
IQ - Iraq 5
KZ - Kazakistan 5
LB - Libano 5
RO - Romania 5
CL - Cile 4
PY - Paraguay 4
BA - Bosnia-Erzegovina 3
BY - Bielorussia 3
DK - Danimarca 3
LU - Lussemburgo 3
MA - Marocco 3
PT - Portogallo 3
TN - Tunisia 3
TW - Taiwan 3
AE - Emirati Arabi Uniti 2
KE - Kenya 2
PE - Perù 2
A1 - Anonimo 1
AF - Afghanistan, Repubblica islamica di 1
AL - Albania 1
BZ - Belize 1
GI - Gibilterra 1
GT - Guatemala 1
IL - Israele 1
JM - Giamaica 1
MD - Moldavia 1
MM - Myanmar 1
NI - Nicaragua 1
NO - Norvegia 1
NP - Nepal 1
PA - Panama 1
PH - Filippine 1
RS - Serbia 1
SN - Senegal 1
SY - Repubblica araba siriana 1
TJ - Tagikistan 1
VE - Venezuela 1
YE - Yemen 1
ZW - Zimbabwe 1
Totale 11.859
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Città #
Singapore 658
Southend 643
Ashburn 534
Fairfield 443
Chandler 441
Dong Ket 325
Bologna 302
Woodbridge 236
Ann Arbor 225
Wilmington 219
Santa Clara 197
Seattle 187
Hong Kong 186
Houston 181
Cambridge 169
Hefei 166
Princeton 155
Beijing 136
Dublin 132
Jacksonville 115
Abidjan 105
Boardman 101
Lomé 88
New York 88
Nanjing 75
Hyderabad 74
Westminster 69
Padova 67
Bremen 55
Seoul 55
Berlin 53
Ho Chi Minh City 51
Milan 51
Dallas 50
Los Angeles 50
Tokyo 45
Jinan 39
Sofia 39
Changsha 38
Shenyang 36
Buffalo 35
Saint Petersburg 35
Hanoi 31
Redwood City 30
Brussels 29
Shanghai 29
Guangzhou 27
Redondo Beach 27
Abeokuta 26
Helsinki 26
Hebei 24
Tianjin 24
Toronto 24
Medford 23
Munich 23
Nanchang 23
Frankfurt am Main 22
Amman 21
Dearborn 20
Mülheim 20
Bern 19
Leawood 18
San Diego 17
Zhengzhou 17
Fremont 16
London 15
Mahé 15
Verona 15
Jiaxing 14
Napoli 14
Caserta 13
Cesena 12
Des Moines 12
Rome 12
Bengaluru 11
Pune 11
Redmond 11
Salerno 11
Taizhou 11
Bures-sur-Yvette 10
Nuremberg 10
Taiyuan 10
Vienna 10
Wuhan 10
Düsseldorf 9
Falls Church 9
Monmouth Junction 9
Phoenix 9
Xi'an 9
Yubileyny 9
Bühl 8
Falkenstein 8
Hangzhou 8
Moncalieri 8
Norwalk 8
Portsmouth 8
Turin 8
Albissola Marina 7
Jakarta 7
Johannesburg 7
Totale 7.843
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Nome #
Balancing Affinity, Selectivity, and Cytotoxicity of Hydrazone-Based G-Quadruplex Ligands for Activation of Interferon β Genes in Cancer Cells 241
Antitumor activity and COMPARE analysis of bis-indole derivatives 224
4-Imidazo[2,1-b]thiazole-1,4-DHPs and neuroprotection: preliminary study in hits searching 219
2-[(E)-3-(6-chloroimidazo[2,1-b]thiazol-5-ylprop-2-enyl]5,6-dimethoxy-3-methyl-1,4-benzo quinone: a new inhibitor of NADH dehydrogenase with antitumor activity 211
Synthesis, in vitro and in vivo biological evaluation of substituted 3-(5-imidazo[2,1-b]thiazolylmethylene)-2-indolinones as new potent anticancer agents 208
Ligand Based Approach to L-Type Calcium Channel by Imidazo[2,1-b]thiazole-1,4-Dihydropyridines: from Heart Activity to Brain Affinity 205
Antitumor Activity of New Substituted 3-(5-Imidazo[2,1-b]thiazolylmethylene)-2-indolinones and 3-(5-Imidazo[2,1-b]thiadiazolylmethylene)-2-indolinones: Selectivity Against Colon Tumor Cells and Effect on Cell Cycle-Related Events. 203
Antitumor Activity of Substituted E-3-(3,4,5-Trimethoxybenzylidene)-1,3-dihydroindol-2-ones 201
Chemopreventive and antioxidant activity of 6-substituted imidazo [2,1-b]thiazoles 201
P53-dependent and p53-independent anticancer activity of a new indole derivative in human osteosarcoma cells 197
Antitumor Activity of Bis-indole Derivatives 196
Diphenidol-related diamines as novel muscarinic M4 receptor antagonists 194
Indole derivative interacts with estrogen receptor beta and inhibits human ovarian cancer cell growth 193
Toward the Development of Specific G‑Quadruplex Binders: Synthesis, Biophysical, and Biological Studies of New Hydrazone Derivatives 192
SUBSTITUTED E-3-(3-INDOLYLMETHYLENE)1,3-DIHYDROINDOL-2-ONES WITH ANTITUMOR ACTIVITY. IN-DEPTH STUDY OF THE EFFECT ON GROWTH OF BREAST CANCER CELLS. 190
2-Indolinone a versatile scaffold for treatment of cancer: A patent review (2008-2014) 188
Bis-guanylhydrazone diimidazo[1,2-a:1,2-c]pyrimidine as a novel and specific G-quadruplex binding motif 185
Investigation on the effects of antimicrobial imidazo[2,1-b]thiazole derivatives on the genitourinary microflora 184
Substituted E-3-(3-Indolylmethylene)-1,3-dihydroindol-2-ones with Antitumor Activity. In Depth Study of the Effect on Growth of Breast Cancer Cells 182
Antitumor Activity of New Substituted 3-(5-Imidazo[2,1-b]thiazolylmethylene)-2-indolinones and Study of Their Effect on the Cell Cycle 181
Synthesis of 3-(Imidazo[2,1-b]thiazol-6-yl)-2H-chromen-2-one derivatives and study of their antiviral activity against parvovirus B19 181
Monohydrazone Based G-Quadruplex Selective Ligands Induce DNA Damage and Genome Instability in Human Cancer Cells 180
Composti organici ad attività antitumorale 179
Substituted E-3-(2-chloro-3-indolylmethylene)1,3-dihydroindol-2-ones with antitumor activity 176
New Antitumor Imidazo[2,1-b]thiazole Guanylhydrazones and Analogues 176
Antitumor activity of imidazo[2,1-b]thiazole guanylhydrazones and analogs. 175
Chemiluminescent high-throughput microassay applied to imidazo[2,1-b]thiazole derivatives as potential acetylcholinesterase and butyrylcholinesterase inhibitors 175
Antitumor activity of compounds bearing the new heterocyclic system thiazolo[2',3':2,3]imidazo[4,5-c]quinoline 170
New isatin derivatives with antioxidant activity 170
Imidazo[2,1-b]thiazole System: a Scaffold Endowing Dihydropyridines With Selective Cardiodepressant Activity 168
Substituted E-3-(2-chloro-3-indolylmethylene)1,3-dihydroindol-2-ones with antitumor activity. Effect on the cell cycle and apoptosis. 166
Nuovi derivati 4-imidazo[2,1-b]tiazoli-4-diidropiridinici quali selettivi calciomodulatori cardiaci 165
Imidazo[2,1-b]thiazole guanylhydrazones as RSK2 inhibitors 164
Intracellular magnesium content decreases during mitochondria-mediated apoptosis induced by a new indole-derivative in human colon cancer cells 164
N-Benzyl-2-chloroindole-3-carboxylic acids as potential anti-inflammatory agents. Synthesis and screening for the effects on human neutrophil functions and on COX1/COX2 activity 163
Attività calcio modulatrice a livello cardiaco e vasale di derivati imidazo[2,1-b]tiazolici 162
p53-dependent and p53-independent anticancer activity of a new indole derivative in human osteosarcoma cells 159
Bis-indole derivatives with antitumor activity turn out to be specific ligands of human telomeric G-quadruplex. 158
A Patent Review on Thiazole Derivatives (2008-2013) 153
Benzoindol-2-one derivatives inducing mitochondria-mediated apoptosis associated with magnesium content decrease 152
Small-Molecules Targeting Sirtuin 1: A Patent Review (2012-2015) 150
Dansyl acetyl trehalose: a novel tool to investigate the cellular fate of trehalose 150
Isatin Bis-Imidathiazole Hybrids Identified as FtsZ Inhibitors with On-Target Activity Against Staphylococcus aureus 148
Diethyl 4-(6-Chloroimidazo[2,1-b]thiazol-5-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate and Ethyl 4-(6-Chloroimidazo[2,1-b]thiazol-5-yl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate 146
Imidazo[2,1-b] Thiazole: Introduction, Current and Perspective 146
Synthesis, in vitro cytotoxicity, molecular docking and ADME study of some indolin-2-one linked 1,2,3-triazole derivatives 146
Attività antitumorale di nuovi 3-(5-imidazo[2,1-b]tiazolilmetilen)-2-indolinoni sostituiti e studio del loro effetto sul ciclo cellulare 145
Synthesis and antitumor activity of Guanylhydrazones from 6-(2,4-dichloro-5-nitrophenyl)imidazo[2,1-b]thiazoles and 6-pyridylimidazo[2,1-b]thiazoles 145
Potential Antitumor Agents. 37. Synthesis and Antitumor Activity of Guanylhydrazones from Imidazo[2,1-b]thiazoles and from the New Heterocyclic System Thiazolo[2',3':2,3]imidazo[4,5-c]quinoline 144
Cytotoxic activities of substituted 3-(3,4,5-trimethoxybenzylidene)- 1,3-dihydroindol-2-ones and studies on their mechanisms of action 141
Substituted E-3-(3-indolylmethylene)1,3-dihydroindol-2-ones with antiproliferative activity. Study of the effects on HL-60 leukemia cells 141
Synthesis and antitumor activity of guanylhydrazones from 6-(2,4-dichloro-5-nitrophenyl)- and 6-pyridyl-imidazo[2,1-b]thiazoles. 140
Substituted (E)-3-(2-chloro-3-indolylmethylene)-1,3-dihydroindol-2-ones as antitumor agents: SARs and study of the mechanism of action 139
Identification of a new bisindolinone arresting IGROV1 cells proliferation 138
Sintesi e attività antitumorale di guanilidrazoni derivati dal nucleo imidazo[2,1-b]tiazolico e dal nuovo sistema eterociclico tiazolo[2',3':2,3]imidazo[4,5-c]chinolina 137
New substituted E-3-(2-Chloro-3-indolylmethylene)1,3-dihydroindol-2-ones with antitumor activity 136
Targeting human telomeric and promoter G-quardruplexes: synthesis, biophysical and biological studies of new guanylhydrazones as potential antitumor agents 134
Synthesis and chemiluminescent high throughput screening for inhibition of acetylcholinesterase activity by imidazo[2,1-b]thiazole derivatives 133
Recent Patents on Thiazole Derivatives Endowed with Antitumor Activity 132
Substituted 3-(5-imidazo[2,1-b]thiazolylmethylene)-2-indolinones and analogues: synthesis, citotoxic activity, and study of the mechanism of action. 131
Synthesis and chemiluminescent high throughput microassay for inhibition of acetylcholinesterase and butyrylcholinesterase activity by imidazo[2,1-b]thiazole derivatives 128
Antitumor activity of bis-indolinone derivatives. 128
Novel thiazole derivatives: a patent review (2008 – 2012; Part 1) 128
Identification of a new benzoindol-2-one derivative as a potential modulator of p53 pathway in cancer cells 120
Cystic Fibrosis: a New Target for 4-Imidazo[2,1-b]thiazole-1,4- Dihydropyridines. 117
Toward the development of specific G-quadruplex binders: biophysical studies of new hydrazone derivatives. 117
Isatin Bis-Indole and Bis-Imidazothiazole Hybrids: Synthesis and Antimicrobial Activity 114
Synthesis and biological evaluation of thiazole derivatives on basic defects underlying cystic fibrosis. 112
Effect of new ubiquinone-imidazo[2,1-b] thiazoles on mitochondrial Complex I (NADH ubiquinone reductase) and on mitochondrial permeability transition pore. 110
Novel thiazole derivatives: a patent review (2008-2012. Part.2) 109
Synthesis and biological evaluation of new bis-indolinone derivatives endowed with cytotoxic activity 109
Synthesis and antiproliferative activity of imidazo[2,1-b][1,3,4]thiadiazole derivatives 105
Sintesi di derivati imidazo[2,1-b]tiazolici e valutazioone dell'attività inibitoria dell'acetilcolinesterasi mediante un metodo HTS chemiluminescente 95
SYNTHESIS OF 3-(5-IMIDAZO[2,1-b]THIAZOLYLMETHYLENE)-2-INDOLINONES INHIBITING TUBULIN ASSEMBLY AND INDUCING APOPTOSIS IN HT-29 COLON CANCER CELLS 89
IDENTIFICATION OF A NEW POTENTIAL LIGAND OF THE ESTROGEN RECEPTOR BETA, INHIBITING HUMAN OVARIAN CANCER CELL GROWTH 86
Potential antitumor agents. 34.(1)Synthesis and antitumor activity of guanylhydrazones from imidazo[2,1-b]thiazoles and from diimidazo[1,2-a:1,2-c]pyrimidine 74
null 72
Small-Molecules Targeting Kinases Involved in Pulmonary Hypertension: a Patent Review (2010-2015) 64
Repurposing 1,4-Dihydropyridine Scaffold: 4-Imidazo[2,1-b]thiazole-Derivatives from Calcium Entry Blockers to a New Approach for Gut Dysfunctional Motility 28
Molecular Tools for Precision Targeting and Detection of G-Quadruplex Structures 5
Totale 12.083
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Categoria #
all - tutte 31.719
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 31.719
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20211.016 0 0 0 0 0 152 40 66 98 87 76 497
2021/20221.480 196 46 72 75 147 95 45 120 61 84 289 250
2022/20231.711 147 291 100 282 120 124 46 104 274 40 120 63
2023/2024585 43 79 29 48 41 176 47 31 10 34 18 29
2024/20252.008 132 274 192 133 314 91 274 64 10 204 87 233
2025/20262.203 367 421 337 353 517 208 0 0 0 0 0 0
Totale 12.083