CRIS Current Research Information System

LOCATELLI, ALESSANDRA
 Distribuzione geografica
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Continente #
NA - Nord America 5.419
AS - Asia 4.447
EU - Europa 3.800
AF - Africa 335
Continente sconosciuto - Info sul continente non disponibili 247
SA - Sud America 187
OC - Oceania 7
Totale 14.442
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Nazione #
US - Stati Uniti d'America 5.316
CN - Cina 1.306
VN - Vietnam 1.132
SG - Singapore 1.114
IT - Italia 1.049
GB - Regno Unito 758
DE - Germania 432
SE - Svezia 314
IN - India 295
FR - Francia 239
HK - Hong Kong 214
UA - Ucraina 180
RU - Federazione Russa 170
NL - Olanda 158
IE - Irlanda 138
BR - Brasile 132
CI - Costa d'Avorio 105
TG - Togo 88
ZA - Sudafrica 74
JP - Giappone 72
KR - Corea 71
FI - Finlandia 70
CA - Canada 64
EE - Estonia 56
BG - Bulgaria 40
BD - Bangladesh 37
BE - Belgio 32
PH - Filippine 30
NG - Nigeria 27
CH - Svizzera 26
AR - Argentina 24
SC - Seychelles 23
AT - Austria 22
JO - Giordania 22
HR - Croazia 21
IR - Iran 21
TH - Thailandia 20
PK - Pakistan 19
IQ - Iraq 17
ID - Indonesia 15
MX - Messico 15
PL - Polonia 15
GR - Grecia 14
CZ - Repubblica Ceca 13
ES - Italia 12
TR - Turchia 12
TW - Taiwan 9
KZ - Kazakistan 8
RO - Romania 8
CO - Colombia 7
LT - Lituania 7
DZ - Algeria 6
EC - Ecuador 6
LB - Libano 6
PT - Portogallo 6
AU - Australia 5
CL - Cile 5
SA - Arabia Saudita 5
AE - Emirati Arabi Uniti 4
BA - Bosnia-Erzegovina 4
PY - Paraguay 4
BY - Bielorussia 3
CR - Costa Rica 3
DK - Danimarca 3
GT - Guatemala 3
KE - Kenya 3
LU - Lussemburgo 3
MA - Marocco 3
PE - Perù 3
TN - Tunisia 3
TT - Trinidad e Tobago 3
UZ - Uzbekistan 3
AL - Albania 2
BB - Barbados 2
BO - Bolivia 2
HN - Honduras 2
JM - Giamaica 2
MM - Myanmar 2
MY - Malesia 2
NI - Nicaragua 2
NZ - Nuova Zelanda 2
PR - Porto Rico 2
UY - Uruguay 2
VE - Venezuela 2
A1 - Anonimo 1
AF - Afghanistan, Repubblica islamica di 1
AM - Armenia 1
BZ - Belize 1
EG - Egitto 1
GD - Grenada 1
GI - Gibilterra 1
IL - Israele 1
KW - Kuwait 1
LA - Repubblica Popolare Democratica del Laos 1
LC - Santa Lucia 1
MD - Moldavia 1
NO - Norvegia 1
NP - Nepal 1
OM - Oman 1
PA - Panama 1
Totale 14.187
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Città #
Singapore 748
Southend 643
Ashburn 598
Fairfield 443
Chandler 441
Bologna 382
San Jose 339
Dong Ket 325
Woodbridge 236
Ann Arbor 225
Wilmington 219
Santa Clara 206
Hong Kong 203
Ho Chi Minh City 198
Seattle 187
Houston 183
Cambridge 171
Hefei 168
Hanoi 157
Princeton 155
Beijing 147
Dublin 137
Boardman 127
Council Bluffs 117
Jacksonville 117
Abidjan 105
New York 102
Lomé 88
Lauterbourg 77
Nanjing 77
Hyderabad 75
Westminster 69
Padova 67
Los Angeles 62
Helsinki 60
Milan 60
Tokyo 60
Seoul 57
Bremen 55
Berlin 53
Dallas 53
Guangzhou 41
Buffalo 39
Changsha 39
Jinan 39
Sofia 39
Shanghai 36
Shenyang 36
Saint Petersburg 35
Da Nang 31
Redwood City 30
Brussels 29
Haiphong 27
Redondo Beach 27
Toronto 27
Abeokuta 26
Frankfurt am Main 26
Hebei 24
Medford 24
Tianjin 24
London 23
Munich 23
Nanchang 23
Amman 22
Dearborn 20
Mülheim 20
Bern 19
São Paulo 19
Leawood 18
Rome 18
San Diego 18
Zhengzhou 18
Orem 17
Fremont 16
Rimini 16
The Dalles 16
Mahé 15
Phoenix 15
Verona 15
Jiaxing 14
Johannesburg 14
Napoli 14
Wuhan 14
Caserta 13
Bengaluru 12
Cesena 12
Des Moines 12
San Francisco 12
Taizhou 12
Chennai 11
Montreal 11
Nuremberg 11
Pune 11
Redmond 11
Salerno 11
Vienna 11
Bures-sur-Yvette 10
Bắc Giang 10
Can Tho 10
Hải Dương 10
Totale 9.188
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Nome #
Balancing Affinity, Selectivity, and Cytotoxicity of Hydrazone-Based G-Quadruplex Ligands for Activation of Interferon β Genes in Cancer Cells 293
Synthesis, in vitro and in vivo biological evaluation of substituted 3-(5-imidazo[2,1-b]thiazolylmethylene)-2-indolinones as new potent anticancer agents 255
4-Imidazo[2,1-b]thiazole-1,4-DHPs and neuroprotection: preliminary study in hits searching 253
Antitumor activity and COMPARE analysis of bis-indole derivatives 247
Ligand Based Approach to L-Type Calcium Channel by Imidazo[2,1-b]thiazole-1,4-Dihydropyridines: from Heart Activity to Brain Affinity 244
Indole derivative interacts with estrogen receptor beta and inhibits human ovarian cancer cell growth 239
Toward the Development of Specific G‑Quadruplex Binders: Synthesis, Biophysical, and Biological Studies of New Hydrazone Derivatives 234
2-[(E)-3-(6-chloroimidazo[2,1-b]thiazol-5-ylprop-2-enyl]5,6-dimethoxy-3-methyl-1,4-benzo quinone: a new inhibitor of NADH dehydrogenase with antitumor activity 232
Antitumor Activity of New Substituted 3-(5-Imidazo[2,1-b]thiazolylmethylene)-2-indolinones and 3-(5-Imidazo[2,1-b]thiadiazolylmethylene)-2-indolinones: Selectivity Against Colon Tumor Cells and Effect on Cell Cycle-Related Events. 230
2-Indolinone a versatile scaffold for treatment of cancer: A patent review (2008-2014) 229
P53-dependent and p53-independent anticancer activity of a new indole derivative in human osteosarcoma cells 226
Antitumor Activity of Bis-indole Derivatives 223
Chemopreventive and antioxidant activity of 6-substituted imidazo [2,1-b]thiazoles 222
Bis-guanylhydrazone diimidazo[1,2-a:1,2-c]pyrimidine as a novel and specific G-quadruplex binding motif 222
Synthesis, in vitro cytotoxicity, molecular docking and ADME study of some indolin-2-one linked 1,2,3-triazole derivatives 222
Diphenidol-related diamines as novel muscarinic M4 receptor antagonists 221
Antitumor Activity of Substituted E-3-(3,4,5-Trimethoxybenzylidene)-1,3-dihydroindol-2-ones 220
Investigation on the effects of antimicrobial imidazo[2,1-b]thiazole derivatives on the genitourinary microflora 219
Monohydrazone Based G-Quadruplex Selective Ligands Induce DNA Damage and Genome Instability in Human Cancer Cells 217
SUBSTITUTED E-3-(3-INDOLYLMETHYLENE)1,3-DIHYDROINDOL-2-ONES WITH ANTITUMOR ACTIVITY. IN-DEPTH STUDY OF THE EFFECT ON GROWTH OF BREAST CANCER CELLS. 214
Composti organici ad attività antitumorale 210
Synthesis of 3-(Imidazo[2,1-b]thiazol-6-yl)-2H-chromen-2-one derivatives and study of their antiviral activity against parvovirus B19 205
Isatin Bis-Imidathiazole Hybrids Identified as FtsZ Inhibitors with On-Target Activity Against Staphylococcus aureus 203
Imidazo[2,1-b]thiazole guanylhydrazones as RSK2 inhibitors 203
Substituted E-3-(3-Indolylmethylene)-1,3-dihydroindol-2-ones with Antitumor Activity. In Depth Study of the Effect on Growth of Breast Cancer Cells 202
Identification of a new bisindolinone arresting IGROV1 cells proliferation 199
Chemiluminescent high-throughput microassay applied to imidazo[2,1-b]thiazole derivatives as potential acetylcholinesterase and butyrylcholinesterase inhibitors 199
New Antitumor Imidazo[2,1-b]thiazole Guanylhydrazones and Analogues 199
New isatin derivatives with antioxidant activity 198
Dansyl acetyl trehalose: a novel tool to investigate the cellular fate of trehalose 197
Antitumor activity of imidazo[2,1-b]thiazole guanylhydrazones and analogs. 195
Antitumor Activity of New Substituted 3-(5-Imidazo[2,1-b]thiazolylmethylene)-2-indolinones and Study of Their Effect on the Cell Cycle 195
Nuovi derivati 4-imidazo[2,1-b]tiazoli-4-diidropiridinici quali selettivi calciomodulatori cardiaci 194
Imidazo[2,1-b]thiazole System: a Scaffold Endowing Dihydropyridines With Selective Cardiodepressant Activity 192
Intracellular magnesium content decreases during mitochondria-mediated apoptosis induced by a new indole-derivative in human colon cancer cells 190
Substituted E-3-(2-chloro-3-indolylmethylene)1,3-dihydroindol-2-ones with antitumor activity. Effect on the cell cycle and apoptosis. 188
Substituted E-3-(2-chloro-3-indolylmethylene)1,3-dihydroindol-2-ones with antitumor activity 185
Attività calcio modulatrice a livello cardiaco e vasale di derivati imidazo[2,1-b]tiazolici 185
p53-dependent and p53-independent anticancer activity of a new indole derivative in human osteosarcoma cells 184
N-Benzyl-2-chloroindole-3-carboxylic acids as potential anti-inflammatory agents. Synthesis and screening for the effects on human neutrophil functions and on COX1/COX2 activity 183
A Patent Review on Thiazole Derivatives (2008-2013) 183
Antitumor activity of compounds bearing the new heterocyclic system thiazolo[2',3':2,3]imidazo[4,5-c]quinoline 179
Bis-indole derivatives with antitumor activity turn out to be specific ligands of human telomeric G-quadruplex. 179
Small-Molecules Targeting Sirtuin 1: A Patent Review (2012-2015) 177
Benzoindol-2-one derivatives inducing mitochondria-mediated apoptosis associated with magnesium content decrease 176
Imidazo[2,1-b] Thiazole: Introduction, Current and Perspective 176
Sintesi e attività antitumorale di guanilidrazoni derivati dal nucleo imidazo[2,1-b]tiazolico e dal nuovo sistema eterociclico tiazolo[2',3':2,3]imidazo[4,5-c]chinolina 171
Cytotoxic activities of substituted 3-(3,4,5-trimethoxybenzylidene)- 1,3-dihydroindol-2-ones and studies on their mechanisms of action 171
Potential Antitumor Agents. 37. Synthesis and Antitumor Activity of Guanylhydrazones from Imidazo[2,1-b]thiazoles and from the New Heterocyclic System Thiazolo[2',3':2,3]imidazo[4,5-c]quinoline 168
Targeting human telomeric and promoter G-quardruplexes: synthesis, biophysical and biological studies of new guanylhydrazones as potential antitumor agents 166
Attività antitumorale di nuovi 3-(5-imidazo[2,1-b]tiazolilmetilen)-2-indolinoni sostituiti e studio del loro effetto sul ciclo cellulare 165
Diethyl 4-(6-Chloroimidazo[2,1-b]thiazol-5-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate and Ethyl 4-(6-Chloroimidazo[2,1-b]thiazol-5-yl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate 164
Substituted 3-(5-imidazo[2,1-b]thiazolylmethylene)-2-indolinones and analogues: synthesis, citotoxic activity, and study of the mechanism of action. 164
New substituted E-3-(2-Chloro-3-indolylmethylene)1,3-dihydroindol-2-ones with antitumor activity 162
Substituted E-3-(3-indolylmethylene)1,3-dihydroindol-2-ones with antiproliferative activity. Study of the effects on HL-60 leukemia cells 162
Substituted (E)-3-(2-chloro-3-indolylmethylene)-1,3-dihydroindol-2-ones as antitumor agents: SARs and study of the mechanism of action 160
Synthesis and antitumor activity of Guanylhydrazones from 6-(2,4-dichloro-5-nitrophenyl)imidazo[2,1-b]thiazoles and 6-pyridylimidazo[2,1-b]thiazoles 159
Recent Patents on Thiazole Derivatives Endowed with Antitumor Activity 156
Synthesis and antitumor activity of guanylhydrazones from 6-(2,4-dichloro-5-nitrophenyl)- and 6-pyridyl-imidazo[2,1-b]thiazoles. 155
Synthesis and chemiluminescent high throughput microassay for inhibition of acetylcholinesterase and butyrylcholinesterase activity by imidazo[2,1-b]thiazole derivatives 155
Isatin Bis-Indole and Bis-Imidazothiazole Hybrids: Synthesis and Antimicrobial Activity 152
Synthesis and chemiluminescent high throughput screening for inhibition of acetylcholinesterase activity by imidazo[2,1-b]thiazole derivatives 152
Novel thiazole derivatives: a patent review (2008 – 2012; Part 1) 152
Antitumor activity of bis-indolinone derivatives. 151
Synthesis and biological evaluation of thiazole derivatives on basic defects underlying cystic fibrosis. 150
Toward the development of specific G-quadruplex binders: biophysical studies of new hydrazone derivatives. 149
Identification of a new benzoindol-2-one derivative as a potential modulator of p53 pathway in cancer cells 148
Synthesis and biological evaluation of new bis-indolinone derivatives endowed with cytotoxic activity 144
Effect of new ubiquinone-imidazo[2,1-b] thiazoles on mitochondrial Complex I (NADH ubiquinone reductase) and on mitochondrial permeability transition pore. 133
Cystic Fibrosis: a New Target for 4-Imidazo[2,1-b]thiazole-1,4- Dihydropyridines. 132
Novel thiazole derivatives: a patent review (2008-2012. Part.2) 131
Synthesis and antiproliferative activity of imidazo[2,1-b][1,3,4]thiadiazole derivatives 125
SYNTHESIS OF 3-(5-IMIDAZO[2,1-b]THIAZOLYLMETHYLENE)-2-INDOLINONES INHIBITING TUBULIN ASSEMBLY AND INDUCING APOPTOSIS IN HT-29 COLON CANCER CELLS 119
Sintesi di derivati imidazo[2,1-b]tiazolici e valutazioone dell'attività inibitoria dell'acetilcolinesterasi mediante un metodo HTS chemiluminescente 114
IDENTIFICATION OF A NEW POTENTIAL LIGAND OF THE ESTROGEN RECEPTOR BETA, INHIBITING HUMAN OVARIAN CANCER CELL GROWTH 98
Potential antitumor agents. 34.(1)Synthesis and antitumor activity of guanylhydrazones from imidazo[2,1-b]thiazoles and from diimidazo[1,2-a:1,2-c]pyrimidine 87
Repurposing 1,4-Dihydropyridine Scaffold: 4-Imidazo[2,1-b]thiazole-Derivatives from Calcium Entry Blockers to a New Approach for Gut Dysfunctional Motility 86
Small-Molecules Targeting Kinases Involved in Pulmonary Hypertension: a Patent Review (2010-2015) 82
Molecular Tools for Precision Targeting and Detection of G-Quadruplex Structures 79
null 72
Identification of MBT3T as a new effective therapeutic option in imatinib-resistant gastrointestinal stromal tumors (GISTs) 70
Totale 14.442
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Categoria #
all - tutte 38.058
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 38.058
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.284 0 46 72 75 147 95 45 120 61 84 289 250
2022/20231.711 147 291 100 282 120 124 46 104 274 40 120 63
2023/2024585 43 79 29 48 41 176 47 31 10 34 18 29
2024/20252.008 132 274 192 133 314 91 274 64 10 204 87 233
2025/20264.271 367 421 337 353 517 250 409 117 802 361 179 158
2026/2027291 153 138 0 0 0 0 0 0 0 0 0 0
Totale 14.442