Imidazo[2,1-b]thiazole is a fused heterobicyclic system containing bridgehead nitrogen atom. Derivatives of this scaffold are especially attractive in the field of medicinal chemistry because of their broad spectrum of biological activities. The imidazo[2,1-b]thiazole system constitutes the core unit of the well-known anthelminthic and immunomodulatory agent Levamisole, marketed under the trade name Ergamisol© and discovered at Janssen Pharmaceutica in 1966.
Leoni, A., Locatelli, A., Morigi, R., Rambaldi, M. (2017). Imidazo[2,1-b] Thiazole: Introduction, Current and Perspective. BIOENERGETICS, 6(1), 1-3 [10.4172/2167-7662.1000151].
Imidazo[2,1-b] Thiazole: Introduction, Current and Perspective
LEONI, ALBERTO;LOCATELLI, ALESSANDRA;MORIGI, RITA;RAMBALDI, MIRELLA
2017
Abstract
Imidazo[2,1-b]thiazole is a fused heterobicyclic system containing bridgehead nitrogen atom. Derivatives of this scaffold are especially attractive in the field of medicinal chemistry because of their broad spectrum of biological activities. The imidazo[2,1-b]thiazole system constitutes the core unit of the well-known anthelminthic and immunomodulatory agent Levamisole, marketed under the trade name Ergamisol© and discovered at Janssen Pharmaceutica in 1966.File in questo prodotto:
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