LEONI, ALBERTO
LEONI, ALBERTO
DIPARTIMENTO DI FARMACIA E BIOTECNOLOGIE
Balancing Affinity, Selectivity, and Cytotoxicity of Hydrazone-Based G-Quadruplex Ligands for Activation of Interferon β Genes in Cancer Cells
2022 Marzano S.; Miglietta G.; Morigi R.; Marinello J.; Arleo A.; Procacci M.; Locatelli A.; Leoni A.; Pagano B.; Randazzo A.; Amato J.; Capranico G.
Isatin Bis-Indole and Bis-Imidazothiazole Hybrids: Synthesis and Antimicrobial Activity
2022 Francesca Bonvicini, Alessandra Locatelli, Rita Morigi, Alberto Leoni, Giovanna Angela Gentilomi
Evaluation of roasting effect on selected green tea volatile flavor compound and pyrazine content by hs-spme gc-ms
2021 Gotti R.; Leoni A.; Fiori J.
Synthesis and biological evaluation of new bis-indolinone derivatives endowed with cytotoxic activity
2021 Morigi R.; Catanzaro E.; Locatelli A.; Calcabrini C.; Pellicioni V.; Leoni A.; Fimognari C.
Monohydrazone Based G-Quadruplex Selective Ligands Induce DNA Damage and Genome Instability in Human Cancer Cells
2020 Amato J.; Miglietta G.; Morigi R.; Iaccarino N.; Locatelli A.; Leoni A.; Novellino E.; Pagano B.; Capranico G.; Randazzo A.
Synthesis and biological evaluation of thiazole derivatives on basic defects underlying cystic fibrosis.
2020 Emanuela Pesce, Nicoletta Pedemonte, Alberto Leoni, Alessandra Locatelli, Rita Morigi
4-Imidazo[2,1-b]thiazole-1,4-DHPs and neuroprotection: preliminary study in hits searching
2019 Leoni, Alberto; Frosini, Maria; Locatelli, Alessandra; Micucci, Matteo; Carotenuto, Claudio; Durante, Miriam; Cosconati, Sandro; Budriesi, Roberta*
Dansyl acetyl trehalose: a novel tool to investigate the cellular fate of trehalose
2019 Alessandra Locatelli, Luisa Iommarini, Alessandra Graziadio, Alberto Leoni, Anna Maria Porcelli, Stefano Iotti, Emil Malucelli, Francesco Francia, Giovanni Venturoli, Giovanna Farruggia
Synthesis of 3-(Imidazo[2,1-b]thiazol-6-yl)-2H-chromen-2-one derivatives and study of their antiviral activity against parvovirus B19
2019 Conti, Ilaria; Morigi, Rita; Locatelli, Alessandra*; Rambaldi, Mirella; Bua, Gloria; Gallinella, Giorgio; Leoni, Alberto
Synthesis, in vitro and in vivo biological evaluation of substituted 3-(5-imidazo[2,1-b]thiazolylmethylene)-2-indolinones as new potent anticancer agents
2019 Morigi, R., Locatelli, A., Leoni, A., Rambaldi, M., Bortolozzi, R., Mattiuzzo, E., Ronca, R., Maccarinelli, F., Hamel, E., Bai, R., Brancale, A., Viola, G.
Investigation on the effects of antimicrobial imidazo[2,1-b]thiazole derivatives on the genitourinary microflora
2018 Morigi, Rita; Vitali, Beatrice; Prata, Cecilia; Palomino, Rogers A. A; Graziadio, Alessandra; Locatelli, Alessandra; Rambaldi, Mirella; Leoni, Alberto
Targeting human telomeric and promoter G-quardruplexes: synthesis, biophysical and biological studies of new guanylhydrazones as potential antitumor agents
2018 R. Morigi, J. Amato, N. Iaccarino, B. Pagano, A. Locatelli, A. Leoni, M. Rambaldi, G. Miglietta, J. Marinello, G. Capranico, E. Novellino, A. Randazzo
A Patent Review on Thiazole Derivatives (2008-2013)
2017 Leoni, Alberto; Locatelli, Alessandra; Morigi, Rita; Rambaldi, Mirella
Ayurvedic preparation of Zingiber officinale Roscoe: effects on cardiac and on smooth muscle parameters
2017 Leoni, Alberto; Budriesi, Roberta; Poli, Ferruccio; Lianza, Mariacaterina; Graziadio, Alessandra; Venturini, Alice; Broccoli, Massimiliano; Micucci, Matteo
Imidazo[2,1-b] Thiazole: Introduction, Current and Perspective
2017 Leoni, Alberto; Locatelli, Alessandra; Morigi, Rita; Rambaldi, Mirella
Toward the development of specific G-quadruplex binders: biophysical studies of new hydrazone derivatives.
2017 N. Iaccarino, J. Amato, R. Morigi, A. Pagano, A. De Magis, G. Capranico, A. Locatelli, A. Graziadio, A. Leoni, M. Rambaldi, E. Novellino, S. Neidle, B. Pagano, A. Randazzo.
2-Indolinone a versatile scaffold for treatment of cancer: A patent review (2008-2014)
2016 Leoni, Alberto; Locatelli, Alessandra; Morigi, Rita; Rambaldi, Mirella
Small-Molecules Targeting Kinases Involved in Pulmonary Hypertension: a Patent Review (2010-2015)
2016 Morigi, Rita; Rambaldi, Mirella; Locatelli, Alessandra; Leoni, Alberto
Toward the Development of Specific G‑Quadruplex Binders: Synthesis, Biophysical, and Biological Studies of New Hydrazone Derivatives
2016 Amato, Jussara; Morigi, Rita; Pagano, Bruno; Pagano, Alessia; Ohnmacht, Stephan; De Magis Alessio; Tiang, Yee-Peng; Capranico, Giovanni; Locatelli, Alessandra; Graziadio, Alessandra; Leoni, Alberto; Rambaldi, Mirella; Novellino, Ettore; Neidle, Stephen; Randazzo, Antonio
p53-dependent and p53-independent anticancer activity of a new indole derivative in human osteosarcoma cells
2015 Graziadio, Alessandra; Locatelli, Alessandra; Leoni, Alberto; Morigi, Rita; Rambaldi, Mirella; Cappadone, Concettina; Merolle, Lucia; Sargenti, Azzurra
| Titolo | Autore(i) | Anno | Periodico | Editore | Tipo | File |
|---|---|---|---|---|---|---|
| Balancing Affinity, Selectivity, and Cytotoxicity of Hydrazone-Based G-Quadruplex Ligands for Activation of Interferon β Genes in Cancer Cells | Marzano S.; Miglietta G.; Morigi R.; Marinello J.; Arleo A.; Procacci M.; Locatelli A.; Leoni A.;... Pagano B.; Randazzo A.; Amato J.; Capranico G. | 2022-01-01 | JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | JMC.pdf; jm2c00772_si_002.pdf |
| Isatin Bis-Indole and Bis-Imidazothiazole Hybrids: Synthesis and Antimicrobial Activity | Francesca Bonvicini, Alessandra Locatelli, Rita Morigi, Alberto Leoni, Giovanna Angela Gentilomi | 2022-01-01 | MOLECULES | - | 1.01 Articolo in rivista | molecules-27-05781.pdf |
| Evaluation of roasting effect on selected green tea volatile flavor compound and pyrazine content by hs-spme gc-ms | Gotti R.; Leoni A.; Fiori J. | 2021-01-01 | APPLIED SCIENCES | - | 1.01 Articolo in rivista | appl sci 2021.pdf |
| Synthesis and biological evaluation of new bis-indolinone derivatives endowed with cytotoxic activity | Morigi R.; Catanzaro E.; Locatelli A.; Calcabrini C.; Pellicioni V.; Leoni A.; Fimognari C. | 2021-01-01 | MOLECULES | - | 1.01 Articolo in rivista | Synthesis and Biological Evaluation of New Bis-Indolinone Derivatives Endowed with Cytotoxic Activity.pdf |
| Monohydrazone Based G-Quadruplex Selective Ligands Induce DNA Damage and Genome Instability in Human Cancer Cells | Amato J.; Miglietta G.; Morigi R.; Iaccarino N.; Locatelli A.; Leoni A.; Novellino E.; Pagano B.;... Capranico G.; Randazzo A. | 2020-01-01 | JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | Monohydrazone-Based-GQuadruplex-Selective-Ligands-Induce-DNA-Damage-and-Genome-Instability-in-Human-Cancer-Cells2020Journal-of-Medicinal-Chemistry.pdf |
| Synthesis and biological evaluation of thiazole derivatives on basic defects underlying cystic fibrosis. | Emanuela Pesce, Nicoletta Pedemonte, Alberto Leoni, Alessandra Locatelli, Rita Morigi | 2020-01-01 | BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | - | 1.01 Articolo in rivista | Synthesis and biological evaluation of thiazole derivatives on basic defects underlying cystic fibrosis..pdf |
| 4-Imidazo[2,1-b]thiazole-1,4-DHPs and neuroprotection: preliminary study in hits searching | Leoni, Alberto; Frosini, Maria; Locatelli, Alessandra; Micucci, Matteo; Carotenuto, Claudio; Dura...nte, Miriam; Cosconati, Sandro; Budriesi, Roberta* | 2019-01-01 | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | copertina e proof pubblicazione Leoni(1).pdf |
| Dansyl acetyl trehalose: a novel tool to investigate the cellular fate of trehalose | Alessandra Locatelli, Luisa Iommarini, Alessandra Graziadio, Alberto Leoni, Anna Maria Porcelli, ...Stefano Iotti, Emil Malucelli, Francesco Francia, Giovanni Venturoli, Giovanna Farruggia | 2019-01-01 | RSC ADVANCES | - | 1.01 Articolo in rivista | Dansyl acetyl trehalose a novel tool to investigate RCS advances 2019.pdf |
| Synthesis of 3-(Imidazo[2,1-b]thiazol-6-yl)-2H-chromen-2-one derivatives and study of their antiviral activity against parvovirus B19 | Conti, Ilaria; Morigi, Rita; Locatelli, Alessandra*; Rambaldi, Mirella; Bua, Gloria; Gallinella, ...Giorgio; Leoni, Alberto | 2019-01-01 | MOLECULES | - | 1.01 Articolo in rivista | molecules-24-01037.pdf |
| Synthesis, in vitro and in vivo biological evaluation of substituted 3-(5-imidazo[2,1-b]thiazolylmethylene)-2-indolinones as new potent anticancer agents | Morigi, R., Locatelli, A., Leoni, A., Rambaldi, M., Bortolozzi, R., Mattiuzzo, E., Ronca, R., Mac...carinelli, F., Hamel, E., Bai, R., Brancale, A., Viola, G. | 2019-01-01 | EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | EJMC 166, 2019, 514 530 Post print .pdf |
| Investigation on the effects of antimicrobial imidazo[2,1-b]thiazole derivatives on the genitourinary microflora | Morigi, Rita; Vitali, Beatrice; Prata, Cecilia; Palomino, Rogers A. A; Graziadio, Alessandra; Loc...atelli, Alessandra; Rambaldi, Mirella; Leoni, Alberto | 2018-01-01 | MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
| Targeting human telomeric and promoter G-quardruplexes: synthesis, biophysical and biological studies of new guanylhydrazones as potential antitumor agents | R. Morigi, J. Amato, N. Iaccarino, B. Pagano, A. Locatelli, A. Leoni, M. Rambaldi, G. Miglietta, ...J. Marinello, G. Capranico, E. Novellino, A. Randazzo | 2018-01-01 | - | - | 4.02 Riassunto (Abstract) | - |
| A Patent Review on Thiazole Derivatives (2008-2013) | Leoni, Alberto; Locatelli, Alessandra; Morigi, Rita; Rambaldi, Mirella | 2017-01-01 | ACTA CHIMICA & PHARMACEUTICA INDICA | - | 1.01 Articolo in rivista | - |
| Ayurvedic preparation of Zingiber officinale Roscoe: effects on cardiac and on smooth muscle parameters | Leoni, Alberto; Budriesi, Roberta; Poli, Ferruccio; Lianza, Mariacaterina; Graziadio, Alessandra;... Venturini, Alice; Broccoli, Massimiliano; Micucci, Matteo | 2017-01-01 | NATURAL PRODUCT RESEARCH | - | 1.01 Articolo in rivista | - |
| Imidazo[2,1-b] Thiazole: Introduction, Current and Perspective | Leoni, Alberto; Locatelli, Alessandra; Morigi, Rita; Rambaldi, Mirella | 2017-01-01 | BIOENERGETICS | - | 1.01 Articolo in rivista | - |
| Toward the development of specific G-quadruplex binders: biophysical studies of new hydrazone derivatives. | N. Iaccarino, J. Amato, R. Morigi, A. Pagano, A. De Magis, G. Capranico, A. Locatelli, A. Graziad...io, A. Leoni, M. Rambaldi, E. Novellino, S. Neidle, B. Pagano, A. Randazzo. | 2017-01-01 | - | - | 4.02 Riassunto (Abstract) | - |
| 2-Indolinone a versatile scaffold for treatment of cancer: A patent review (2008-2014) | Leoni, Alberto; Locatelli, Alessandra; Morigi, Rita; Rambaldi, Mirella | 2016-01-01 | EXPERT OPINION ON THERAPEUTIC PATENTS | - | 1.01 Articolo in rivista | - |
| Small-Molecules Targeting Kinases Involved in Pulmonary Hypertension: a Patent Review (2010-2015) | Morigi, Rita; Rambaldi, Mirella; Locatelli, Alessandra; Leoni, Alberto | 2016-01-01 | CURRENT MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | - |
| Toward the Development of Specific G‑Quadruplex Binders: Synthesis, Biophysical, and Biological Studies of New Hydrazone Derivatives | Amato, Jussara; Morigi, Rita; Pagano, Bruno; Pagano, Alessia; Ohnmacht, Stephan; De Magis Alessio...; Tiang, Yee-Peng; Capranico, Giovanni; Locatelli, Alessandra; Graziadio, Alessandra; Leoni, Alberto; Rambaldi, Mirella; Novellino, Ettore; Neidle, Stephen; Randazzo, Antonio | 2016-01-01 | JOURNAL OF MEDICINAL CHEMISTRY | - | 1.01 Articolo in rivista | J Med Chem, 2016, 59 (12), 5706–5720 post print(3).pdf |
| p53-dependent and p53-independent anticancer activity of a new indole derivative in human osteosarcoma cells | Graziadio, Alessandra; Locatelli, Alessandra; Leoni, Alberto; Morigi, Rita; Rambaldi, Mirella; Ca...ppadone, Concettina; Merolle, Lucia; Sargenti, Azzurra | 2015-01-01 | - | Società Chimica Italiana | 4.02 Riassunto (Abstract) | - |