Clear cell sarcoma of the kidney (CCSK) is a rare pediatric renal tumor that is frequently difficult to distinguish among other childhood renal tumors due to its histological heterogeneity. This work evaluates genetic abnormalities carried by a series of CCSK samples by whole transcriptome sequencing (WTS), to identify molecular biomarkers that could improve the diagnostic process.
Whole transcriptome sequencing identifies BCOR internal tandem duplication as a common feature of clear cell sarcoma of the kidney / Astolfi, Annalisa; Melchionda, Fraia; Perotti, Daniela; Fois, Maura; Indio, Valentina; Urbini, Milena; Genovese, Chiara Giusy; Collini, Paola; Salfi, Nunzio; Nantron, Marilina; D'Angelo, Paolo; Spreafico, Filippo; Pession, Andrea. - In: ONCOTARGET. - ISSN 1949-2553. - ELETTRONICO. - 6:38(2015), pp. 40934-40939. [10.18632/oncotarget.5882]
Whole transcriptome sequencing identifies BCOR internal tandem duplication as a common feature of clear cell sarcoma of the kidney
ASTOLFI, ANNALISA;MELCHIONDA, FRAIA;FOIS, MAURA;INDIO, VALENTINA;URBINI, MILENA;GENOVESE, CHIARA GIUSY;SALFI, NUNZIO;PESSION, ANDREA
2015
Abstract
Clear cell sarcoma of the kidney (CCSK) is a rare pediatric renal tumor that is frequently difficult to distinguish among other childhood renal tumors due to its histological heterogeneity. This work evaluates genetic abnormalities carried by a series of CCSK samples by whole transcriptome sequencing (WTS), to identify molecular biomarkers that could improve the diagnostic process.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
