CANDELETTI, SANZIO
 Distribuzione geografica
Continente #
NA - Nord America 5.732
AS - Asia 5.662
EU - Europa 5.335
AF - Africa 405
SA - Sud America 323
OC - Oceania 11
Continente sconosciuto - Info sul continente non disponibili 2
Totale 17.470
Nazione #
US - Stati Uniti d'America 5.645
IT - Italia 2.126
SG - Singapore 1.581
CN - Cina 1.580
VN - Vietnam 1.354
GB - Regno Unito 875
DE - Germania 437
SE - Svezia 379
HK - Hong Kong 371
FR - Francia 333
UA - Ucraina 265
IN - India 261
BR - Brasile 225
RU - Federazione Russa 201
CI - Costa d'Avorio 170
IE - Irlanda 155
NL - Olanda 140
KR - Corea 131
JP - Giappone 96
FI - Finlandia 94
TG - Togo 82
ZA - Sudafrica 74
BG - Bulgaria 70
CH - Svizzera 50
CA - Canada 49
EE - Estonia 48
SC - Seychelles 36
BD - Bangladesh 33
ID - Indonesia 32
AR - Argentina 29
ES - Italia 29
JO - Giordania 29
TH - Thailandia 29
IQ - Iraq 27
PH - Filippine 26
GR - Grecia 25
PL - Polonia 24
BE - Belgio 20
CL - Cile 20
TR - Turchia 19
TW - Taiwan 18
MX - Messico 17
EC - Ecuador 15
AT - Austria 14
RO - Romania 12
PK - Pakistan 11
AU - Australia 10
SA - Arabia Saudita 10
VE - Venezuela 10
PE - Perù 9
CZ - Repubblica Ceca 7
HN - Honduras 7
IL - Israele 7
LY - Libia 7
MY - Malesia 7
AE - Emirati Arabi Uniti 6
DZ - Algeria 6
PY - Paraguay 6
AL - Albania 5
CO - Colombia 5
DK - Danimarca 5
MA - Marocco 5
UZ - Uzbekistan 5
AZ - Azerbaigian 4
EG - Egitto 4
GT - Guatemala 4
KE - Kenya 4
LT - Lituania 4
DO - Repubblica Dominicana 3
GH - Ghana 3
HU - Ungheria 3
IR - Iran 3
OM - Oman 3
PT - Portogallo 3
TN - Tunisia 3
UY - Uruguay 3
A2 - ???statistics.table.value.countryCode.A2??? 2
BA - Bosnia-Erzegovina 2
CR - Costa Rica 2
ET - Etiopia 2
JM - Giamaica 2
KH - Cambogia 2
KZ - Kazakistan 2
LB - Libano 2
MD - Moldavia 2
MN - Mongolia 2
NG - Nigeria 2
SN - Senegal 2
TJ - Tagikistan 2
AM - Armenia 1
BH - Bahrain 1
BN - Brunei Darussalam 1
BW - Botswana 1
BY - Bielorussia 1
CG - Congo 1
CY - Cipro 1
GA - Gabon 1
GD - Grenada 1
GE - Georgia 1
GY - Guiana 1
Totale 17.455
Città #
Singapore 1.074
Southend 741
Ashburn 545
Fairfield 464
San Jose 437
Chandler 401
Santa Clara 378
Hong Kong 351
Hefei 299
Dong Ket 294
Ho Chi Minh City 275
Bologna 272
Wilmington 244
Hanoi 241
Woodbridge 216
Seattle 209
Beijing 199
Princeton 191
Houston 183
Abidjan 170
Cambridge 165
Milan 156
Ann Arbor 153
Dublin 151
Jacksonville 151
Dallas 133
Boardman 123
Seoul 110
Lauterbourg 106
Turin 104
Rome 103
Nanjing 85
Tokyo 84
Lomé 82
Westminster 79
Padova 76
Helsinki 69
Sofia 69
Los Angeles 68
Berlin 63
Council Bluffs 61
Jinan 61
New York 53
Shenyang 43
Tappahannock 43
Haiphong 42
Saint Petersburg 41
Buffalo 40
Guangzhou 38
Frankfurt am Main 36
Florence 34
Shanghai 34
Da Nang 33
Redondo Beach 33
Naples 32
Changsha 31
Amman 29
São Paulo 28
Medford 27
Mülheim 27
Tianjin 27
Dearborn 25
Ningbo 25
San Diego 25
Bengaluru 24
Hyderabad 23
Hebei 21
London 21
Nuremberg 20
Orem 20
Zhengzhou 20
Brussels 19
Jakarta 19
Jiaxing 19
Washington 18
Bangkok 17
Hangzhou 17
Mahé 17
Phoenix 17
Yubileyny 17
Lappeenranta 16
Norwalk 16
Redmond 16
Catania 15
Chicago 15
Denver 15
Des Moines 15
Forlì 15
Paris 15
Amsterdam 14
Cagliari 14
Falls Church 14
Johannesburg 14
Nanchang 14
Palermo 14
San Francisco 14
Hải Dương 13
Lanzhou 13
Montreal 13
Taiyuan 13
Totale 10.779
Nome #
Farmacologia degli analgesici oppiacei 1.793
Chronic Trazodone and Citalopram Treatments Increase Trophic Factor and Circadian Rhythm Gene Expression in Rat Brain Regions Relevant for Antidepressant Efficacy 272
On the toxicity of e-cigarettes consumption: Focus on pathological cellular mechanisms 259
Effects of unburned tobacco smoke on inflammatory and oxidative mediators in the rat prefrontal cortex 241
Prolonged nicotine exposure, via electronic cigarette, selectively increases Bdnf/TrkB transcription, dynorphin peptide levels and OLIG2 in male rat VTA 237
The active second-generation proteasome inhibitor oprozomib reverts the oxaliplatin-induced neuropathy symptoms 233
Supraspinal melatonin MT2 receptor agonism alleviates pain via a neural circuit that recruits mu opioid receptors 223
Activation of PPARγ Attenuates the Expression of Physical and Affective Nicotine Withdrawal Symptoms through Mechanisms Involving Amygdala and Hippocampus Neurotransmission 220
Kainate Seizures Increase Nociceptin/Orphanin FQ Release in the Rat Hippocampus and Thalamus: a Microdialysis Study. 216
Acute and chronic cannabinoid extracts administration affects motor function in a CREAE model of multiple sclerosis 216
Treatment with the neurotoxic Aβ (25-35) peptide modulates the expression of neuroprotective factors Pin1, Sirtuin 1, and brain-derived neurotrophic factor in SH-SY5Y human neuroblastoma cells 206
Early-life nicotine or cotinine exposure produces long-lasting sleep alterations and downregulation of hippocampal corticosteroid receptors in adult mice 205
Differential time course of the effects of kappa-opioid agonist treatment on dynorphin A and on k-opioid receptor density 201
Role of serotonin on cocaine mediated effects on prodynorphin gene expression in the rat brain. 196
N/OFQ system in brain areas of nerve-injured mice: Its role in different aspects of neuropathic pain 194
∆(9)-Tetrahydrocannabinol decreases NOP receptor density and mRNA levels in human SH-SY5Y cells. 191
Unburned Tobacco Smoke Affects Neuroinflammation-Related Pathways in the Rat Mesolimbic System. 190
Cocaine and ethanol target 26S proteasome activity and gene expression in neuroblastoma cells 186
Nociceptive responses in melatonin MT2 receptor knockout mice compared to MT1 and double MT1/MT2 receptor knockout mice 185
Blockade of nociceptin/orphanin FQ transmission attenuates symptoms and neurodegenation associated with Parkinson's disease. 184
Mystic Acetaldehyde: The Never-Ending Story on Alcoholism 183
Alterations in prodynorphin gene expression and dynorphin levels in different brain regions after chronic administration of 14-methoxy-metopon and oxycodone-6-oxime. 179
Different alcohol exposures induce selective alterations on the expression of dynorphin and nociceptin systems related genes in rat brain. 176
Brain interstitial nociceptin/orphanin FQ levels are elevated in Parkinson's disease. 175
Targeting the JAK/STAT Pathway: A Combined Ligand- And Target-Based Approach 175
Current and Future Therapeutic Options in Pain Management: Multi-mechanistic Opioids Involving Both MOR and NOP Receptor Activation 172
Dynorphinergic system alterations in the corticostriatal circuitry of neuropathic mice support its role in the negative affective component of pain. 171
Early social isolation differentially affects the glucocorticoid receptor system and alcohol-seeking behavior in male and female Marchigian Sardinian alcohol-preferring rats 167
Kainic Acid Down-regulates NOP Receptor Density and Gene Expression in Human Neuroblastoma SH-SY5Y Cells. 167
Peripheral leukocyte expression of the potential biomarker proteins Bdnf, Sirt1, and Psen1 is not regulated by promoter methylation in Alzheimer's disease patients 167
An Exploratory Pilot Study of Changes in Global DNA Methylation in Patients Undergoing Major Breast Surgery Under Opioid-Based General Anesthesia 167
Alghedon Fentanyl Transdermal System 166
Chronic and acute effects of 3,4-methylenedioxy-N-methylamphetamine ('Ecstasy') administration on the dynorphinergic system in the rat brain. 165
Proteasome subunit and opioid receptor gene expression down-regulation induced by paraquat and maneb in human neuroblastoma SH-SY5Y cells. 164
Alterations of CREB and DARPP-32 phosphorylation following cocaine and monoaminergic uptake inhibitors. 164
Morphine and Fentanyl Differently Affect MOP and NOP Gene Expression in Human Neuroblastoma SH-SY5Y Cells. 163
Modulation of the negative affective dimension of pain: Focus on selected neuropeptidergic system contributions 162
Effects of Different Opioid Drugs on Oxidative Status and Proteasome Activity in SH-SY5Y Cells 161
Combined exposure to agriculture pesticides, paraquat and maneb, induces alterations in the N/OFQ—NOPr and PDYN/KOPr systems in rats: Relevance to sporadic Parkinson's disease 161
NOP receptor antagonism reduces alcohol drinking in male and female rats through mechanisms involving the central amygdala and ventral tegmental area 159
The standardized Withania somnifera Dunal root extract alters basal and morphine-induced opioid receptor gene expression changes in neuroblastoma cells. 158
Dynorphin/KOP and nociceptin/NOP gene expression and epigenetic changes by cocaine in rat striatum and nucleus accumbens 157
Effects of prolonged treatment with the opiate tramadol on prodynorphin gene expression in rat CNS. 156
Ethanol Induces Epigenetic Modulation of Prodynorphin and Pronociceptin Gene Expression in the Rat Amygdala Complex. 156
Opioid gene expression changes and post-translational histone modifications at promoter regions in the rat nucleus accumbens after acute and repeated 3,4-methylenedioxy-methamphetamine (MDMA) exposure 156
EFFECTS OF 3,4-METHYLENDIOXY-N-METHYLAMPHETAMINE (MDMA, ‘ECSTASY’) ADMINISTRATION ON THE DYNORPHINERGIC SYSTEM IN THE RAT BRAIN. 154
Interplay between the endogenous opioid system and proteasome complex: Beyond signaling 154
Effects of acute ethanol exposure on class I HDACs family enzymes in wild-type and BDNF(+/-) mice 153
Human apolipoprotein E4 modulates the expression of Pin1, Sirtuin 1, and Presenilin 1 in brain regions of targeted replacement apoE mice 152
Alterations in prodynorphin gene expression in 6-OHDA lesioned rat brain. 152
Sex-dependent effect of inflammatory pain on negative affective states is prevented by kappa opioid receptors blockade in the nucleus accumbens shell 151
Alterations of N/OFQ and NOP receptor gene expression in the substantia nigra and caudate putamen of MPP(+) and 6-OHDA lesioned rats. 150
Dysregulation of nociceptin/orphanin fq and dynorphin systems in the extended amygdala of alcohol preferring marchigian sardinian (Msp) rats 150
The k-opioid receptor agonist U-69593 prevents cocaine-induced DARPP-32 phosphorylation at Thr34 in the rat brain 148
Regulation of the genes encoding the ppN/OFQ and NOP receptor 148
Opioid Receptor Gene Expression in Human Neuroblastoma SH-SY5Y Cells Following Tapentadol Exposure 147
A new potent analgesic agent with reduced liability to produce morphine tolerance 147
Application of Molecular Topology to the Search of Novel NSAIDs: Experimental Validation of Activity 146
Evidence of a PPARγ-mediated mechanism in the ability of Withania somnifera to attenuate tolerance to the antinociceptive effects of morphine 145
Chronic cocaine produces decreases in N/OFQ peptide levels in select rat brain regions. 144
Chronic delta(9)-tetrahydrocannabinol during adolescence provokes sex-dependent changes in the emotional profile in adult rats: behavioral and biochemical correlates. 144
Nociceptin levels in the CSF of chronic pain patients with or without intrathecal administration of morphine. 142
Selective DNA methylation of BDNF promoter in bipolar disorder: differences among patients with BDI and BDII. 141
Alcohol exposures induce selective alterations on endogenous opioid system genes regulation in rat amygdala: possible epigenetic mechanisms 138
Interplay between prokineticins and histone demethylase kdm6a in a murine model of bortezomib-induced neuropathy 138
Role of serotonin in the regulation of the dynorphinergic system by a kappa-opioid agonist and cocaine treatment in rat CNS. 137
Cocaine affects NOP receptor gene expression in SH-SY5Y cells 137
Effects of the selective norepinephrine uptake inhibitor nisoxetine on prodynorphin gene expression in rat CNS 137
Regulation of opioid gene expression in the rat brainstem by 3,4-methylenedioxymethamphetamine (MDMA): role of serotonin and involvement of CREB and ERK cascade. 135
Nociceptin/orphanin FQ prevents the antinociceptive action of paracetamol on the rat hot plate test. 135
Possibile role of NOCICEPTIN/OFQ-NOP system in experimental models of Parkinson disease, 133
Activation of Antioxidant and Proteolytic Pathways in the Nigrostriatal Dopaminergic System After 3,4-Methylenedioxymethamphetamine Administration: Sex-Related Differences 133
Tapentadol: An analgesic that differs from classic opioids due to its noradrenergic mechanism of action 131
Outcomes of early social experiences on glucocorticoid and endocannabinoid systems in the prefrontal cortex of male and female adolescent rats 130
Delta9-tetrahydrocannabinol down regulates NOP receptor gene expression in SH-SY5Y cells 129
Regulation of NOP receptor density by delta-9-tetrahydrocannabinol treatment in SH-SY5Y cells. 128
Il Sistema Oppioide 128
Safe use of opioids in chronic kidney disease and hemodialysis patients: Tips and tricks for non-pain specialists 128
Alterations of the dynorphinergic system during tolerance development in rat brain by novel opioid compounds 127
Pharmacology of opiate analgesics for chronic pain management - La gestione del dolore cronico: Farmacologia degli analgesici oppiacei 126
ROLE OF DIFFERENT NEUROTRANSMITTERS ON COCAINE-MEDIATED EFFECTS ON PRODYNORPHIN GENE EXPRESSION AND CREB ACTIVATION IN THE RAT BRAIN. 126
Nociceptive behavior and central neuropeptidergic dysregulations in male and female mice of a Fabry disease animal model 126
Modulation of nociceptin/NOP system by delta9-THC in SH-SY5Y cell line 124
Investigation on DNA methylation status of opioid peptides promoters in PBMCs of subjects with bipolar disorder 124
A role for epigenetic mechanisms in the regulation of prodynorphin expression by alcohol 122
Different impact of chronic tramadol or morphine on prodynorphin gene expression 121
Short-term withdrawal from repeated exposure to cocaine during adolescence modulates dynorphin mRNA levels and BDNF signaling in the rat nucleus accumbens 121
INVOLVEMENT OF SEROTONIN IN DYNORPHINERGIC SYSTEM REGULATION BY KAPPA-OPIOID AGONIST AND COCAINE TREATMENTS 119
The prolonged buprenorphine administration reduces the NOP receptor density in rat cerebral areas 118
Cross-talk between CB1 and NOP receptors in human neuroblastoma SH-SY5Y cells 118
Transcriptional and epigenetic phenomena in peripheral blood cells of monozygotic twins discordant for alzheimer's disease, a case report 118
Communal nesting shapes the sex-dependent glutamatergic response to early life stress in the rat prefrontal cortex 116
Ethanol and acetaldehyde exposure induces specific epigenetic modifications in the prodynorphin gene promoter in a human neuroblastoma cell line. 110
Long lasting effects of perinatal exposure to the Chlorpyrifos pesticide on sleep, breathing, and neuroinflammation in adult mice 107
Alterations in neuroinflammation-related pathways induced by unburned tobacco smoke in the rat mesolimbic system 101
NOP receptor density is reduced by chronic infusion with buprenorphine in selected rat brain areas. 100
Pin1 contribution to Alzheimer's disease: transcriptional and epigenetic mechanisms in patients with late-onset Alzheimer's disease. 99
Selective DNA methylation of BDNF promoter in bipolar disorder 98
Fentanyl citrate sublingual formulation (Vellofent®) for quick BTcP hindering 97
Nociceptin Modulates Bronchoconstriction Induced by Sensory Nerve Activation in Mouse Lung. 95
Totale 17.173
Categoria #
all - tutte 46.266
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 46.266


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021511 0 0 0 0 0 0 0 0 0 0 110 401
2021/20221.515 160 66 102 88 144 100 78 143 53 48 252 281
2022/20231.958 188 272 78 221 124 180 71 113 396 45 190 80
2023/2024896 51 115 55 89 60 128 41 47 55 84 85 86
2024/20253.174 212 426 269 237 541 153 293 101 76 157 167 542
2025/20265.776 423 655 633 420 658 328 674 357 1.046 467 115 0
Totale 17.869