CANDELETTI, SANZIO
 Distribuzione geografica
Continente #
NA - Nord America 6.041
AS - Asia 5.833
EU - Europa 5.502
AF - Africa 405
SA - Sud America 338
OC - Oceania 11
Continente sconosciuto - Info sul continente non disponibili 2
Totale 18.132
Nazione #
US - Stati Uniti d'America 5.933
IT - Italia 2.289
CN - Cina 1.589
SG - Singapore 1.587
VN - Vietnam 1.358
GB - Regno Unito 875
DE - Germania 437
SE - Svezia 379
HK - Hong Kong 373
FR - Francia 333
UA - Ucraina 265
IN - India 261
BR - Brasile 236
RU - Federazione Russa 201
BD - Bangladesh 182
CI - Costa d'Avorio 170
IE - Irlanda 155
NL - Olanda 142
KR - Corea 131
JP - Giappone 96
FI - Finlandia 94
TG - Togo 82
ZA - Sudafrica 74
BG - Bulgaria 70
CA - Canada 63
CH - Svizzera 50
EE - Estonia 48
SC - Seychelles 36
ID - Indonesia 32
AR - Argentina 29
ES - Italia 29
JO - Giordania 29
TH - Thailandia 29
IQ - Iraq 27
PH - Filippine 26
GR - Grecia 25
PL - Polonia 24
CL - Cile 23
MX - Messico 22
BE - Belgio 21
TR - Turchia 19
TW - Taiwan 18
AT - Austria 15
EC - Ecuador 15
PK - Pakistan 12
RO - Romania 12
VE - Venezuela 11
AU - Australia 10
SA - Arabia Saudita 10
PE - Perù 9
CZ - Repubblica Ceca 7
HN - Honduras 7
IL - Israele 7
LY - Libia 7
MY - Malesia 7
AE - Emirati Arabi Uniti 6
DZ - Algeria 6
PY - Paraguay 6
AL - Albania 5
CO - Colombia 5
DK - Danimarca 5
GT - Guatemala 5
MA - Marocco 5
UZ - Uzbekistan 5
AZ - Azerbaigian 4
EG - Egitto 4
KE - Kenya 4
LT - Lituania 4
DO - Repubblica Dominicana 3
GH - Ghana 3
HU - Ungheria 3
IR - Iran 3
JM - Giamaica 3
OM - Oman 3
PT - Portogallo 3
TN - Tunisia 3
UY - Uruguay 3
A2 - ???statistics.table.value.countryCode.A2??? 2
BA - Bosnia-Erzegovina 2
CR - Costa Rica 2
ET - Etiopia 2
KH - Cambogia 2
KZ - Kazakistan 2
LB - Libano 2
MD - Moldavia 2
MN - Mongolia 2
NG - Nigeria 2
SN - Senegal 2
TJ - Tagikistan 2
AM - Armenia 1
BH - Bahrain 1
BN - Brunei Darussalam 1
BW - Botswana 1
BY - Bielorussia 1
CG - Congo 1
CY - Cipro 1
GA - Gabon 1
GD - Grenada 1
GE - Georgia 1
GY - Guiana 1
Totale 18.117
Città #
Singapore 1.080
Southend 741
Ashburn 567
Fairfield 464
San Jose 457
Chandler 401
Santa Clara 391
Hong Kong 353
Bologna 307
Hefei 299
Dong Ket 294
Ho Chi Minh City 277
Wilmington 244
Hanoi 243
Woodbridge 216
Seattle 209
Beijing 205
Princeton 191
Houston 184
Milan 181
Abidjan 170
Boardman 170
Cambridge 165
Ann Arbor 153
Jacksonville 152
Dublin 151
Dallas 137
Rome 114
Seoul 110
Lauterbourg 106
Turin 106
Council Bluffs 105
Los Angeles 98
Nanjing 85
Tokyo 84
Lomé 82
Westminster 80
Padova 76
New York 71
Helsinki 69
Sofia 69
Berlin 63
Jinan 61
Buffalo 46
Shenyang 43
Tappahannock 43
Florence 42
Haiphong 42
Saint Petersburg 41
Guangzhou 38
São Paulo 38
Frankfurt am Main 36
Naples 36
Shanghai 35
Da Nang 33
Redondo Beach 33
Changsha 31
Amman 29
Medford 27
Mülheim 27
Tianjin 27
Dearborn 25
Ningbo 25
San Diego 25
Bengaluru 24
Hyderabad 24
London 22
Hebei 21
Orem 21
Nuremberg 20
Zhengzhou 20
Brussels 19
Jakarta 19
Jiaxing 19
Washington 18
Bangkok 17
Chicago 17
Hangzhou 17
Mahé 17
Palermo 17
Phoenix 17
Toronto 17
Yubileyny 17
Lappeenranta 16
Norwalk 16
Redmond 16
Cagliari 15
Catania 15
Denver 15
Des Moines 15
Forlì 15
Modena 15
Montreal 15
Paris 15
San Francisco 15
Amsterdam 14
Falls Church 14
Johannesburg 14
Nanchang 14
The Dalles 14
Totale 11.119
Nome #
Farmacologia degli analgesici oppiacei 1.843
Chronic Trazodone and Citalopram Treatments Increase Trophic Factor and Circadian Rhythm Gene Expression in Rat Brain Regions Relevant for Antidepressant Efficacy 310
On the toxicity of e-cigarettes consumption: Focus on pathological cellular mechanisms 275
Supraspinal melatonin MT2 receptor agonism alleviates pain via a neural circuit that recruits mu opioid receptors 265
Effects of unburned tobacco smoke on inflammatory and oxidative mediators in the rat prefrontal cortex 253
Prolonged nicotine exposure, via electronic cigarette, selectively increases Bdnf/TrkB transcription, dynorphin peptide levels and OLIG2 in male rat VTA 245
The active second-generation proteasome inhibitor oprozomib reverts the oxaliplatin-induced neuropathy symptoms 239
Activation of PPARγ Attenuates the Expression of Physical and Affective Nicotine Withdrawal Symptoms through Mechanisms Involving Amygdala and Hippocampus Neurotransmission 225
Unburned Tobacco Smoke Affects Neuroinflammation-Related Pathways in the Rat Mesolimbic System. 216
Kainate Seizures Increase Nociceptin/Orphanin FQ Release in the Rat Hippocampus and Thalamus: a Microdialysis Study. 216
Acute and chronic cannabinoid extracts administration affects motor function in a CREAE model of multiple sclerosis 216
Treatment with the neurotoxic Aβ (25-35) peptide modulates the expression of neuroprotective factors Pin1, Sirtuin 1, and brain-derived neurotrophic factor in SH-SY5Y human neuroblastoma cells 214
Early-life nicotine or cotinine exposure produces long-lasting sleep alterations and downregulation of hippocampal corticosteroid receptors in adult mice 210
Differential time course of the effects of kappa-opioid agonist treatment on dynorphin A and on k-opioid receptor density 201
Role of serotonin on cocaine mediated effects on prodynorphin gene expression in the rat brain. 196
N/OFQ system in brain areas of nerve-injured mice: Its role in different aspects of neuropathic pain 196
∆(9)-Tetrahydrocannabinol decreases NOP receptor density and mRNA levels in human SH-SY5Y cells. 191
Nociceptive responses in melatonin MT2 receptor knockout mice compared to MT1 and double MT1/MT2 receptor knockout mice 191
Alterations in prodynorphin gene expression and dynorphin levels in different brain regions after chronic administration of 14-methoxy-metopon and oxycodone-6-oxime. 189
Cocaine and ethanol target 26S proteasome activity and gene expression in neuroblastoma cells 188
Blockade of nociceptin/orphanin FQ transmission attenuates symptoms and neurodegenation associated with Parkinson's disease. 187
Mystic Acetaldehyde: The Never-Ending Story on Alcoholism 183
Targeting the JAK/STAT Pathway: A Combined Ligand- And Target-Based Approach 181
Current and Future Therapeutic Options in Pain Management: Multi-mechanistic Opioids Involving Both MOR and NOP Receptor Activation 180
Brain interstitial nociceptin/orphanin FQ levels are elevated in Parkinson's disease. 179
Different alcohol exposures induce selective alterations on the expression of dynorphin and nociceptin systems related genes in rat brain. 176
Dynorphinergic system alterations in the corticostriatal circuitry of neuropathic mice support its role in the negative affective component of pain. 174
Peripheral leukocyte expression of the potential biomarker proteins Bdnf, Sirt1, and Psen1 is not regulated by promoter methylation in Alzheimer's disease patients 171
An Exploratory Pilot Study of Changes in Global DNA Methylation in Patients Undergoing Major Breast Surgery Under Opioid-Based General Anesthesia 171
Early social isolation differentially affects the glucocorticoid receptor system and alcohol-seeking behavior in male and female Marchigian Sardinian alcohol-preferring rats 170
Chronic delta(9)-tetrahydrocannabinol during adolescence provokes sex-dependent changes in the emotional profile in adult rats: behavioral and biochemical correlates. 170
Kainic Acid Down-regulates NOP Receptor Density and Gene Expression in Human Neuroblastoma SH-SY5Y Cells. 170
Proteasome subunit and opioid receptor gene expression down-regulation induced by paraquat and maneb in human neuroblastoma SH-SY5Y cells. 166
Alghedon Fentanyl Transdermal System 166
Modulation of the negative affective dimension of pain: Focus on selected neuropeptidergic system contributions 166
Chronic and acute effects of 3,4-methylenedioxy-N-methylamphetamine ('Ecstasy') administration on the dynorphinergic system in the rat brain. 165
Effects of Different Opioid Drugs on Oxidative Status and Proteasome Activity in SH-SY5Y Cells 164
Morphine and Fentanyl Differently Affect MOP and NOP Gene Expression in Human Neuroblastoma SH-SY5Y Cells. 164
Alterations of CREB and DARPP-32 phosphorylation following cocaine and monoaminergic uptake inhibitors. 164
Combined exposure to agriculture pesticides, paraquat and maneb, induces alterations in the N/OFQ—NOPr and PDYN/KOPr systems in rats: Relevance to sporadic Parkinson's disease 161
The standardized Withania somnifera Dunal root extract alters basal and morphine-induced opioid receptor gene expression changes in neuroblastoma cells. 161
Effects of prolonged treatment with the opiate tramadol on prodynorphin gene expression in rat CNS. 160
NOP receptor antagonism reduces alcohol drinking in male and female rats through mechanisms involving the central amygdala and ventral tegmental area 160
Ethanol Induces Epigenetic Modulation of Prodynorphin and Pronociceptin Gene Expression in the Rat Amygdala Complex. 159
Opioid gene expression changes and post-translational histone modifications at promoter regions in the rat nucleus accumbens after acute and repeated 3,4-methylenedioxy-methamphetamine (MDMA) exposure 158
Dynorphin/KOP and nociceptin/NOP gene expression and epigenetic changes by cocaine in rat striatum and nucleus accumbens 157
Interplay between the endogenous opioid system and proteasome complex: Beyond signaling 157
Sex-dependent effect of inflammatory pain on negative affective states is prevented by kappa opioid receptors blockade in the nucleus accumbens shell 156
EFFECTS OF 3,4-METHYLENDIOXY-N-METHYLAMPHETAMINE (MDMA, ‘ECSTASY’) ADMINISTRATION ON THE DYNORPHINERGIC SYSTEM IN THE RAT BRAIN. 156
Effects of acute ethanol exposure on class I HDACs family enzymes in wild-type and BDNF(+/-) mice 155
Dysregulation of nociceptin/orphanin fq and dynorphin systems in the extended amygdala of alcohol preferring marchigian sardinian (Msp) rats 155
Human apolipoprotein E4 modulates the expression of Pin1, Sirtuin 1, and Presenilin 1 in brain regions of targeted replacement apoE mice 152
Alterations in prodynorphin gene expression in 6-OHDA lesioned rat brain. 152
Alterations of N/OFQ and NOP receptor gene expression in the substantia nigra and caudate putamen of MPP(+) and 6-OHDA lesioned rats. 150
A new potent analgesic agent with reduced liability to produce morphine tolerance 150
Regulation of the genes encoding the ppN/OFQ and NOP receptor 150
The k-opioid receptor agonist U-69593 prevents cocaine-induced DARPP-32 phosphorylation at Thr34 in the rat brain 149
Evidence of a PPARγ-mediated mechanism in the ability of Withania somnifera to attenuate tolerance to the antinociceptive effects of morphine 148
Nociceptin levels in the CSF of chronic pain patients with or without intrathecal administration of morphine. 147
Opioid Receptor Gene Expression in Human Neuroblastoma SH-SY5Y Cells Following Tapentadol Exposure 147
Chronic cocaine produces decreases in N/OFQ peptide levels in select rat brain regions. 146
Application of Molecular Topology to the Search of Novel NSAIDs: Experimental Validation of Activity 146
Interplay between prokineticins and histone demethylase kdm6a in a murine model of bortezomib-induced neuropathy 142
Long lasting effects of perinatal exposure to the Chlorpyrifos pesticide on sleep, breathing, and neuroinflammation in adult mice 141
Selective DNA methylation of BDNF promoter in bipolar disorder: differences among patients with BDI and BDII. 141
Role of serotonin in the regulation of the dynorphinergic system by a kappa-opioid agonist and cocaine treatment in rat CNS. 139
Cocaine affects NOP receptor gene expression in SH-SY5Y cells 139
Alcohol exposures induce selective alterations on endogenous opioid system genes regulation in rat amygdala: possible epigenetic mechanisms 139
Safe use of opioids in chronic kidney disease and hemodialysis patients: Tips and tricks for non-pain specialists 139
Activation of Antioxidant and Proteolytic Pathways in the Nigrostriatal Dopaminergic System After 3,4-Methylenedioxymethamphetamine Administration: Sex-Related Differences 139
Outcomes of early social experiences on glucocorticoid and endocannabinoid systems in the prefrontal cortex of male and female adolescent rats 137
Effects of the selective norepinephrine uptake inhibitor nisoxetine on prodynorphin gene expression in rat CNS 137
Regulation of opioid gene expression in the rat brainstem by 3,4-methylenedioxymethamphetamine (MDMA): role of serotonin and involvement of CREB and ERK cascade. 136
Possibile role of NOCICEPTIN/OFQ-NOP system in experimental models of Parkinson disease, 135
Nociceptin/orphanin FQ prevents the antinociceptive action of paracetamol on the rat hot plate test. 135
Regulation of NOP receptor density by delta-9-tetrahydrocannabinol treatment in SH-SY5Y cells. 133
Il Sistema Oppioide 133
Delta9-tetrahydrocannabinol down regulates NOP receptor gene expression in SH-SY5Y cells 132
Tapentadol: An analgesic that differs from classic opioids due to its noradrenergic mechanism of action 132
Nociceptive behavior and central neuropeptidergic dysregulations in male and female mice of a Fabry disease animal model 129
Pharmacology of opiate analgesics for chronic pain management - La gestione del dolore cronico: Farmacologia degli analgesici oppiacei 128
Alterations of the dynorphinergic system during tolerance development in rat brain by novel opioid compounds 128
Modulation of nociceptin/NOP system by delta9-THC in SH-SY5Y cell line 127
ROLE OF DIFFERENT NEUROTRANSMITTERS ON COCAINE-MEDIATED EFFECTS ON PRODYNORPHIN GENE EXPRESSION AND CREB ACTIVATION IN THE RAT BRAIN. 127
Investigation on DNA methylation status of opioid peptides promoters in PBMCs of subjects with bipolar disorder 125
Different impact of chronic tramadol or morphine on prodynorphin gene expression 123
A role for epigenetic mechanisms in the regulation of prodynorphin expression by alcohol 122
Short-term withdrawal from repeated exposure to cocaine during adolescence modulates dynorphin mRNA levels and BDNF signaling in the rat nucleus accumbens 122
Cross-talk between CB1 and NOP receptors in human neuroblastoma SH-SY5Y cells 121
The prolonged buprenorphine administration reduces the NOP receptor density in rat cerebral areas 120
INVOLVEMENT OF SEROTONIN IN DYNORPHINERGIC SYSTEM REGULATION BY KAPPA-OPIOID AGONIST AND COCAINE TREATMENTS 119
Transcriptional and epigenetic phenomena in peripheral blood cells of monozygotic twins discordant for alzheimer's disease, a case report 119
Communal nesting shapes the sex-dependent glutamatergic response to early life stress in the rat prefrontal cortex 116
Prolonged nicotine exposure, via electronic cigarettes, selectively enhances the transcription of Bdnf/TrkB and elevates dynorphin peptide and OLIG2 levels in the rat VTA 114
Ethanol and acetaldehyde exposure induces specific epigenetic modifications in the prodynorphin gene promoter in a human neuroblastoma cell line. 111
Alterations in neuroinflammation-related pathways induced by unburned tobacco smoke in the rat mesolimbic system 107
Pin1 contribution to Alzheimer's disease: transcriptional and epigenetic mechanisms in patients with late-onset Alzheimer's disease. 107
Acute kappa opioid receptor blocking disrupts the pro-cognitive effect of cannabidiol in neuropathic rats 105
NOP receptor density is reduced by chronic infusion with buprenorphine in selected rat brain areas. 100
Selective DNA methylation of BDNF promoter in bipolar disorder 99
Totale 17.676
Categoria #
all - tutte 48.403
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 48.403


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021401 0 0 0 0 0 0 0 0 0 0 0 401
2021/20221.515 160 66 102 88 144 100 78 143 53 48 252 281
2022/20231.958 188 272 78 221 124 180 71 113 396 45 190 80
2023/2024896 51 115 55 89 60 128 41 47 55 84 85 86
2024/20253.174 212 426 269 237 541 153 293 101 76 157 167 542
2025/20266.441 423 655 633 420 658 328 674 357 1.046 467 305 475
Totale 18.534