CANDELETTI, SANZIO
 Distribuzione geografica
Continente #
NA - Nord America 6.751
AS - Asia 5.884
EU - Europa 5.573
AF - Africa 405
Continente sconosciuto - Info sul continente non disponibili 405
SA - Sud America 343
OC - Oceania 11
Totale 19.372
Nazione #
US - Stati Uniti d'America 6.613
IT - Italia 2.349
SG - Singapore 1.605
CN - Cina 1.596
VN - Vietnam 1.360
GB - Regno Unito 876
DE - Germania 438
SE - Svezia 382
HK - Hong Kong 378
FR - Francia 333
UA - Ucraina 266
IN - India 261
BR - Brasile 238
RU - Federazione Russa 201
BD - Bangladesh 198
CI - Costa d'Avorio 170
IE - Irlanda 155
NL - Olanda 143
KR - Corea 132
JP - Giappone 96
FI - Finlandia 94
TG - Togo 82
ZA - Sudafrica 74
CA - Canada 73
BG - Bulgaria 70
CH - Svizzera 50
EE - Estonia 48
SC - Seychelles 36
ID - Indonesia 33
ES - Italia 30
AR - Argentina 29
JO - Giordania 29
TH - Thailandia 29
IQ - Iraq 27
PL - Polonia 27
PH - Filippine 26
GR - Grecia 25
CL - Cile 24
MX - Messico 22
BE - Belgio 21
TR - Turchia 19
TW - Taiwan 18
EC - Ecuador 16
AT - Austria 15
PK - Pakistan 12
RO - Romania 12
VE - Venezuela 11
AU - Australia 10
PE - Perù 10
SA - Arabia Saudita 10
HN - Honduras 9
CR - Costa Rica 8
CZ - Repubblica Ceca 7
GT - Guatemala 7
IL - Israele 7
LY - Libia 7
MY - Malesia 7
AE - Emirati Arabi Uniti 6
DZ - Algeria 6
JM - Giamaica 6
PY - Paraguay 6
AL - Albania 5
CO - Colombia 5
DK - Danimarca 5
MA - Marocco 5
UZ - Uzbekistan 5
AZ - Azerbaigian 4
EG - Egitto 4
KE - Kenya 4
LT - Lituania 4
DO - Repubblica Dominicana 3
GH - Ghana 3
HU - Ungheria 3
IR - Iran 3
OM - Oman 3
PR - Porto Rico 3
PT - Portogallo 3
TN - Tunisia 3
UY - Uruguay 3
A2 - ???statistics.table.value.countryCode.A2??? 2
AM - Armenia 2
BA - Bosnia-Erzegovina 2
ET - Etiopia 2
KH - Cambogia 2
KZ - Kazakistan 2
LB - Libano 2
MD - Moldavia 2
MN - Mongolia 2
NG - Nigeria 2
SN - Senegal 2
TJ - Tagikistan 2
BB - Barbados 1
BH - Bahrain 1
BN - Brunei Darussalam 1
BQ - ???statistics.table.value.countryCode.BQ??? 1
BW - Botswana 1
BY - Bielorussia 1
CG - Congo 1
CY - Cipro 1
GA - Gabon 1
Totale 18.949
Città #
Singapore 1.096
Southend 741
Ashburn 588
San Jose 482
Fairfield 464
Chandler 401
Santa Clara 401
Hong Kong 356
Bologna 322
Hefei 299
Dong Ket 294
Ho Chi Minh City 277
Wilmington 245
Hanoi 243
Woodbridge 216
Seattle 213
Beijing 209
Council Bluffs 197
Princeton 191
Milan 187
Houston 184
Abidjan 170
Boardman 170
Cambridge 165
Ann Arbor 153
Jacksonville 152
Dublin 151
Dallas 149
Rome 119
Seoul 110
Turin 108
Los Angeles 107
Lauterbourg 106
Nanjing 85
Tokyo 84
Lomé 82
Westminster 80
New York 77
Padova 76
Helsinki 69
Sofia 69
Berlin 64
Jinan 61
Buffalo 48
Florence 43
Shenyang 43
Tappahannock 43
Haiphong 42
Saint Petersburg 41
São Paulo 40
Guangzhou 38
Naples 37
Frankfurt am Main 36
Shanghai 35
Da Nang 33
Redondo Beach 33
Changsha 31
Amman 29
Medford 27
Mülheim 27
Tianjin 27
Dearborn 26
Ningbo 25
San Diego 25
Bengaluru 24
Hyderabad 24
Orem 24
London 22
Phoenix 22
Atlanta 21
Hebei 21
San Francisco 21
Jakarta 20
Nuremberg 20
Zhengzhou 20
Brussels 19
Jiaxing 19
Toronto 19
Washington 18
Bangkok 17
Cagliari 17
Chicago 17
Hangzhou 17
Mahé 17
Montreal 17
Palermo 17
Yubileyny 17
Denver 16
Lappeenranta 16
Modena 16
Norwalk 16
Redmond 16
Brooklyn 15
Catania 15
Des Moines 15
Forlì 15
Paris 15
Amsterdam 14
Boston 14
Falls Church 14
Totale 11.389
Nome #
Farmacologia degli analgesici oppiacei 1.873
Unburned Tobacco Smoke Affects Neuroinflammation-Related Pathways in the Rat Mesolimbic System. 497
Chronic Trazodone and Citalopram Treatments Increase Trophic Factor and Circadian Rhythm Gene Expression in Rat Brain Regions Relevant for Antidepressant Efficacy 329
Evidence of a PPARγ-mediated mechanism in the ability of Withania somnifera to attenuate tolerance to the antinociceptive effects of morphine 281
On the toxicity of e-cigarettes consumption: Focus on pathological cellular mechanisms 277
Supraspinal melatonin MT2 receptor agonism alleviates pain via a neural circuit that recruits mu opioid receptors 269
Effects of unburned tobacco smoke on inflammatory and oxidative mediators in the rat prefrontal cortex 257
Prolonged nicotine exposure, via electronic cigarette, selectively increases Bdnf/TrkB transcription, dynorphin peptide levels and OLIG2 in male rat VTA 250
The active second-generation proteasome inhibitor oprozomib reverts the oxaliplatin-induced neuropathy symptoms 241
Activation of PPARγ Attenuates the Expression of Physical and Affective Nicotine Withdrawal Symptoms through Mechanisms Involving Amygdala and Hippocampus Neurotransmission 228
Acute and chronic cannabinoid extracts administration affects motor function in a CREAE model of multiple sclerosis 220
Kainate Seizures Increase Nociceptin/Orphanin FQ Release in the Rat Hippocampus and Thalamus: a Microdialysis Study. 218
Treatment with the neurotoxic Aβ (25-35) peptide modulates the expression of neuroprotective factors Pin1, Sirtuin 1, and brain-derived neurotrophic factor in SH-SY5Y human neuroblastoma cells 218
Early-life nicotine or cotinine exposure produces long-lasting sleep alterations and downregulation of hippocampal corticosteroid receptors in adult mice 215
Differential time course of the effects of kappa-opioid agonist treatment on dynorphin A and on k-opioid receptor density 205
Role of serotonin on cocaine mediated effects on prodynorphin gene expression in the rat brain. 200
N/OFQ system in brain areas of nerve-injured mice: Its role in different aspects of neuropathic pain 198
Alterations in prodynorphin gene expression and dynorphin levels in different brain regions after chronic administration of 14-methoxy-metopon and oxycodone-6-oxime. 195
∆(9)-Tetrahydrocannabinol decreases NOP receptor density and mRNA levels in human SH-SY5Y cells. 194
Nociceptive responses in melatonin MT2 receptor knockout mice compared to MT1 and double MT1/MT2 receptor knockout mice 193
Blockade of nociceptin/orphanin FQ transmission attenuates symptoms and neurodegenation associated with Parkinson's disease. 190
Cocaine and ethanol target 26S proteasome activity and gene expression in neuroblastoma cells 189
Current and Future Therapeutic Options in Pain Management: Multi-mechanistic Opioids Involving Both MOR and NOP Receptor Activation 188
Mystic Acetaldehyde: The Never-Ending Story on Alcoholism 185
Targeting the JAK/STAT Pathway: A Combined Ligand- And Target-Based Approach 185
Brain interstitial nociceptin/orphanin FQ levels are elevated in Parkinson's disease. 182
Different alcohol exposures induce selective alterations on the expression of dynorphin and nociceptin systems related genes in rat brain. 178
Early social isolation differentially affects the glucocorticoid receptor system and alcohol-seeking behavior in male and female Marchigian Sardinian alcohol-preferring rats 177
Dynorphinergic system alterations in the corticostriatal circuitry of neuropathic mice support its role in the negative affective component of pain. 174
An Exploratory Pilot Study of Changes in Global DNA Methylation in Patients Undergoing Major Breast Surgery Under Opioid-Based General Anesthesia 174
Chronic delta(9)-tetrahydrocannabinol during adolescence provokes sex-dependent changes in the emotional profile in adult rats: behavioral and biochemical correlates. 173
Peripheral leukocyte expression of the potential biomarker proteins Bdnf, Sirt1, and Psen1 is not regulated by promoter methylation in Alzheimer's disease patients 173
Kainic Acid Down-regulates NOP Receptor Density and Gene Expression in Human Neuroblastoma SH-SY5Y Cells. 171
Modulation of the negative affective dimension of pain: Focus on selected neuropeptidergic system contributions 171
The standardized Withania somnifera Dunal root extract alters basal and morphine-induced opioid receptor gene expression changes in neuroblastoma cells. 170
Proteasome subunit and opioid receptor gene expression down-regulation induced by paraquat and maneb in human neuroblastoma SH-SY5Y cells. 168
Alghedon Fentanyl Transdermal System 168
Morphine and Fentanyl Differently Affect MOP and NOP Gene Expression in Human Neuroblastoma SH-SY5Y Cells. 167
Chronic and acute effects of 3,4-methylenedioxy-N-methylamphetamine ('Ecstasy') administration on the dynorphinergic system in the rat brain. 167
Effects of prolonged treatment with the opiate tramadol on prodynorphin gene expression in rat CNS. 166
Alterations of CREB and DARPP-32 phosphorylation following cocaine and monoaminergic uptake inhibitors. 166
Effects of Different Opioid Drugs on Oxidative Status and Proteasome Activity in SH-SY5Y Cells 165
Combined exposure to agriculture pesticides, paraquat and maneb, induces alterations in the N/OFQ—NOPr and PDYN/KOPr systems in rats: Relevance to sporadic Parkinson's disease 163
NOP receptor antagonism reduces alcohol drinking in male and female rats through mechanisms involving the central amygdala and ventral tegmental area 162
Ethanol Induces Epigenetic Modulation of Prodynorphin and Pronociceptin Gene Expression in the Rat Amygdala Complex. 161
Opioid gene expression changes and post-translational histone modifications at promoter regions in the rat nucleus accumbens after acute and repeated 3,4-methylenedioxy-methamphetamine (MDMA) exposure 160
Interplay between the endogenous opioid system and proteasome complex: Beyond signaling 159
EFFECTS OF 3,4-METHYLENDIOXY-N-METHYLAMPHETAMINE (MDMA, ‘ECSTASY’) ADMINISTRATION ON THE DYNORPHINERGIC SYSTEM IN THE RAT BRAIN. 158
Dynorphin/KOP and nociceptin/NOP gene expression and epigenetic changes by cocaine in rat striatum and nucleus accumbens 158
Sex-dependent effect of inflammatory pain on negative affective states is prevented by kappa opioid receptors blockade in the nucleus accumbens shell 157
Dysregulation of nociceptin/orphanin fq and dynorphin systems in the extended amygdala of alcohol preferring marchigian sardinian (Msp) rats 157
Effects of acute ethanol exposure on class I HDACs family enzymes in wild-type and BDNF(+/-) mice 156
Human apolipoprotein E4 modulates the expression of Pin1, Sirtuin 1, and Presenilin 1 in brain regions of targeted replacement apoE mice 155
Alterations in prodynorphin gene expression in 6-OHDA lesioned rat brain. 154
Regulation of the genes encoding the ppN/OFQ and NOP receptor 154
The k-opioid receptor agonist U-69593 prevents cocaine-induced DARPP-32 phosphorylation at Thr34 in the rat brain 152
Long lasting effects of perinatal exposure to the Chlorpyrifos pesticide on sleep, breathing, and neuroinflammation in adult mice 151
A new potent analgesic agent with reduced liability to produce morphine tolerance 151
Safe use of opioids in chronic kidney disease and hemodialysis patients: Tips and tricks for non-pain specialists 151
Alterations of N/OFQ and NOP receptor gene expression in the substantia nigra and caudate putamen of MPP(+) and 6-OHDA lesioned rats. 150
Opioid Receptor Gene Expression in Human Neuroblastoma SH-SY5Y Cells Following Tapentadol Exposure 149
Nociceptin levels in the CSF of chronic pain patients with or without intrathecal administration of morphine. 148
Chronic cocaine produces decreases in N/OFQ peptide levels in select rat brain regions. 147
Application of Molecular Topology to the Search of Novel NSAIDs: Experimental Validation of Activity 147
Selective DNA methylation of BDNF promoter in bipolar disorder: differences among patients with BDI and BDII. 147
Alcohol exposures induce selective alterations on endogenous opioid system genes regulation in rat amygdala: possible epigenetic mechanisms 145
Activation of Antioxidant and Proteolytic Pathways in the Nigrostriatal Dopaminergic System After 3,4-Methylenedioxymethamphetamine Administration: Sex-Related Differences 144
Role of serotonin in the regulation of the dynorphinergic system by a kappa-opioid agonist and cocaine treatment in rat CNS. 143
Interplay between prokineticins and histone demethylase kdm6a in a murine model of bortezomib-induced neuropathy 143
Cocaine affects NOP receptor gene expression in SH-SY5Y cells 140
Effects of the selective norepinephrine uptake inhibitor nisoxetine on prodynorphin gene expression in rat CNS 140
Regulation of opioid gene expression in the rat brainstem by 3,4-methylenedioxymethamphetamine (MDMA): role of serotonin and involvement of CREB and ERK cascade. 139
Nociceptin/orphanin FQ prevents the antinociceptive action of paracetamol on the rat hot plate test. 139
Outcomes of early social experiences on glucocorticoid and endocannabinoid systems in the prefrontal cortex of male and female adolescent rats 138
Il Sistema Oppioide 138
Possibile role of NOCICEPTIN/OFQ-NOP system in experimental models of Parkinson disease, 136
Regulation of NOP receptor density by delta-9-tetrahydrocannabinol treatment in SH-SY5Y cells. 135
Nociceptive behavior and central neuropeptidergic dysregulations in male and female mice of a Fabry disease animal model 135
Delta9-tetrahydrocannabinol down regulates NOP receptor gene expression in SH-SY5Y cells 133
Tapentadol: An analgesic that differs from classic opioids due to its noradrenergic mechanism of action 133
Pharmacology of opiate analgesics for chronic pain management - La gestione del dolore cronico: Farmacologia degli analgesici oppiacei 132
Alterations of the dynorphinergic system during tolerance development in rat brain by novel opioid compounds 129
Modulation of nociceptin/NOP system by delta9-THC in SH-SY5Y cell line 128
ROLE OF DIFFERENT NEUROTRANSMITTERS ON COCAINE-MEDIATED EFFECTS ON PRODYNORPHIN GENE EXPRESSION AND CREB ACTIVATION IN THE RAT BRAIN. 128
Different impact of chronic tramadol or morphine on prodynorphin gene expression 127
Investigation on DNA methylation status of opioid peptides promoters in PBMCs of subjects with bipolar disorder 126
A role for epigenetic mechanisms in the regulation of prodynorphin expression by alcohol 126
The prolonged buprenorphine administration reduces the NOP receptor density in rat cerebral areas 124
Short-term withdrawal from repeated exposure to cocaine during adolescence modulates dynorphin mRNA levels and BDNF signaling in the rat nucleus accumbens 123
Cross-talk between CB1 and NOP receptors in human neuroblastoma SH-SY5Y cells 122
Communal nesting shapes the sex-dependent glutamatergic response to early life stress in the rat prefrontal cortex 121
INVOLVEMENT OF SEROTONIN IN DYNORPHINERGIC SYSTEM REGULATION BY KAPPA-OPIOID AGONIST AND COCAINE TREATMENTS 121
Prolonged nicotine exposure, via electronic cigarettes, selectively enhances the transcription of Bdnf/TrkB and elevates dynorphin peptide and OLIG2 levels in the rat VTA 120
Transcriptional and epigenetic phenomena in peripheral blood cells of monozygotic twins discordant for alzheimer's disease, a case report 120
Ethanol and acetaldehyde exposure induces specific epigenetic modifications in the prodynorphin gene promoter in a human neuroblastoma cell line. 112
Alterations in neuroinflammation-related pathways induced by unburned tobacco smoke in the rat mesolimbic system 111
Acute kappa opioid receptor blocking disrupts the pro-cognitive effect of cannabidiol in neuropathic rats 111
Pin1 contribution to Alzheimer's disease: transcriptional and epigenetic mechanisms in patients with late-onset Alzheimer's disease. 109
NOP receptor density is reduced by chronic infusion with buprenorphine in selected rat brain areas. 103
Selective DNA methylation of BDNF promoter in bipolar disorder 101
Totale 18.427
Categoria #
all - tutte 50.931
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 50.931


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.355 0 66 102 88 144 100 78 143 53 48 252 281
2022/20231.958 188 272 78 221 124 180 71 113 396 45 190 80
2023/2024896 51 115 55 89 60 128 41 47 55 84 85 86
2024/20253.174 212 426 269 237 541 153 293 101 76 157 167 542
2025/20266.478 423 655 633 420 658 328 674 357 1.046 467 305 512
2026/2027801 462 339 0 0 0 0 0 0 0 0 0 0
Totale 19.372