CANDELETTI, SANZIO
 Distribuzione geografica
Continente #
NA - Nord America 4.211
EU - Europa 4.161
AS - Asia 1.784
AF - Africa 279
SA - Sud America 15
OC - Oceania 7
Continente sconosciuto - Info sul continente non disponibili 2
Totale 10.459
Nazione #
US - Stati Uniti d'America 4.182
IT - Italia 1.615
GB - Regno Unito 826
CN - Cina 642
SG - Singapore 506
SE - Svezia 369
VN - Vietnam 368
DE - Germania 361
UA - Ucraina 259
IN - India 187
FR - Francia 159
IE - Irlanda 148
RU - Federazione Russa 130
CI - Costa d'Avorio 116
TG - Togo 81
BG - Bulgaria 70
ZA - Sudafrica 56
EE - Estonia 47
CH - Svizzera 40
NL - Olanda 26
FI - Finlandia 22
JO - Giordania 22
CA - Canada 20
BE - Belgio 19
GR - Grecia 19
SC - Seychelles 18
ID - Indonesia 17
RO - Romania 10
CL - Cile 8
ES - Italia 8
AU - Australia 7
HN - Honduras 7
LY - Libia 7
PL - Polonia 7
CZ - Repubblica Ceca 6
JP - Giappone 6
TR - Turchia 6
AT - Austria 5
HK - Hong Kong 5
KR - Corea 4
PE - Perù 4
AL - Albania 3
IL - Israele 3
SA - Arabia Saudita 3
UZ - Uzbekistan 3
A2 - ???statistics.table.value.countryCode.A2??? 2
BA - Bosnia-Erzegovina 2
BD - Bangladesh 2
DK - Danimarca 2
EC - Ecuador 2
IR - Iran 2
PH - Filippine 2
PK - Pakistan 2
PT - Portogallo 2
AE - Emirati Arabi Uniti 1
BR - Brasile 1
CR - Costa Rica 1
LB - Libano 1
LU - Lussemburgo 1
MD - Moldavia 1
ME - Montenegro 1
MX - Messico 1
NG - Nigeria 1
NO - Norvegia 1
RS - Serbia 1
SM - San Marino 1
TH - Thailandia 1
TW - Taiwan 1
Totale 10.459
Città #
Southend 741
Fairfield 464
Singapore 450
Chandler 401
Santa Clara 366
Dong Ket 294
Ashburn 277
Wilmington 244
Woodbridge 216
Seattle 205
Princeton 191
Bologna 181
Houston 177
Cambridge 165
Ann Arbor 153
Jacksonville 151
Dublin 144
Boardman 120
Abidjan 116
Milan 101
Turin 97
Nanjing 83
Lomé 81
Westminster 78
Rome 75
Padova 74
Sofia 69
Berlin 61
Jinan 54
Tappahannock 43
Saint Petersburg 41
Shenyang 40
Beijing 36
Naples 28
Medford 27
Mülheim 27
Dearborn 25
Guangzhou 24
San Diego 24
Ningbo 23
Amman 22
Tianjin 22
Changsha 21
Hebei 21
Hyderabad 21
Brussels 19
Jiaxing 19
Jakarta 17
Mahé 17
Shanghai 17
Washington 17
Norwalk 16
Redmond 16
Zhengzhou 16
Des Moines 15
Florence 15
Forlì 15
Helsinki 15
Falls Church 14
Catania 13
London 13
Nanchang 13
New York 13
Taiyuan 13
Lanzhou 12
Cagliari 11
Haikou 11
Ferrara 10
Hangzhou 10
Olalla 10
Redwood City 10
Toronto 10
Verona 10
Bari 9
Modena 9
Moscow 9
Palermo 9
Bern 8
Imola 8
Paris 8
Phoenix 8
Brescia 7
Lappeenranta 7
Los Angeles 7
Shenzhen 7
Taizhou 7
Tegucigalpa 7
Tripoli 7
Dallas 6
Genoa 6
Pescara 6
Sibiu 6
Valencia 6
Venice 6
Wenzhou 6
Frankfurt am Main 5
Genzano Di Roma 5
Harbin 5
Lecce 5
Lugano 5
Totale 6.845
Nome #
Farmacologia degli analgesici oppiacei 1.333
Acute and chronic cannabinoid extracts administration affects motor function in a CREAE model of multiple sclerosis 161
Kainate Seizures Increase Nociceptin/Orphanin FQ Release in the Rat Hippocampus and Thalamus: a Microdialysis Study. 160
The active second-generation proteasome inhibitor oprozomib reverts the oxaliplatin-induced neuropathy symptoms 156
Activation of PPARγ Attenuates the Expression of Physical and Affective Nicotine Withdrawal Symptoms through Mechanisms Involving Amygdala and Hippocampus Neurotransmission 155
Role of serotonin on cocaine mediated effects on prodynorphin gene expression in the rat brain. 148
Cocaine and ethanol target 26S proteasome activity and gene expression in neuroblastoma cells 148
Brain interstitial nociceptin/orphanin FQ levels are elevated in Parkinson's disease. 145
Differential time course of the effects of kappa-opioid agonist treatment on dynorphin A and on k-opioid receptor density 144
Chronic and acute effects of 3,4-methylenedioxy-N-methylamphetamine ('Ecstasy') administration on the dynorphinergic system in the rat brain. 140
Mystic Acetaldehyde: The Never-Ending Story on Alcoholism 138
Kainic Acid Down-regulates NOP Receptor Density and Gene Expression in Human Neuroblastoma SH-SY5Y Cells. 135
Alterations of CREB and DARPP-32 phosphorylation following cocaine and monoaminergic uptake inhibitors. 133
∆(9)-Tetrahydrocannabinol decreases NOP receptor density and mRNA levels in human SH-SY5Y cells. 129
N/OFQ system in brain areas of nerve-injured mice: Its role in different aspects of neuropathic pain 129
Alterations in prodynorphin gene expression and dynorphin levels in different brain regions after chronic administration of 14-methoxy-metopon and oxycodone-6-oxime. 127
Different alcohol exposures induce selective alterations on the expression of dynorphin and nociceptin systems related genes in rat brain. 127
Blockade of nociceptin/orphanin FQ transmission attenuates symptoms and neurodegenation associated with Parkinson's disease. 125
Treatment with the neurotoxic Aβ (25-35) peptide modulates the expression of neuroprotective factors Pin1, Sirtuin 1, and brain-derived neurotrophic factor in SH-SY5Y human neuroblastoma cells 122
Alghedon Fentanyl Transdermal System 122
Application of Molecular Topology to the Search of Novel NSAIDs: Experimental Validation of Activity 119
Dynorphin/KOP and nociceptin/NOP gene expression and epigenetic changes by cocaine in rat striatum and nucleus accumbens 119
Combined exposure to agriculture pesticides, paraquat and maneb, induces alterations in the N/OFQ—NOPr and PDYN/KOPr systems in rats: Relevance to sporadic Parkinson's disease 118
The k-opioid receptor agonist U-69593 prevents cocaine-induced DARPP-32 phosphorylation at Thr34 in the rat brain 116
Dynorphinergic system alterations in the corticostriatal circuitry of neuropathic mice support its role in the negative affective component of pain. 114
Morphine and Fentanyl Differently Affect MOP and NOP Gene Expression in Human Neuroblastoma SH-SY5Y Cells. 113
Alterations of N/OFQ and NOP receptor gene expression in the substantia nigra and caudate putamen of MPP(+) and 6-OHDA lesioned rats. 113
Chronic cocaine produces decreases in N/OFQ peptide levels in select rat brain regions. 112
Chronic delta(9)-tetrahydrocannabinol during adolescence provokes sex-dependent changes in the emotional profile in adult rats: behavioral and biochemical correlates. 112
Proteasome subunit and opioid receptor gene expression down-regulation induced by paraquat and maneb in human neuroblastoma SH-SY5Y cells. 112
Opioid gene expression changes and post-translational histone modifications at promoter regions in the rat nucleus accumbens after acute and repeated 3,4-methylenedioxy-methamphetamine (MDMA) exposure 111
Ethanol Induces Epigenetic Modulation of Prodynorphin and Pronociceptin Gene Expression in the Rat Amygdala Complex. 110
Peripheral leukocyte expression of the potential biomarker proteins Bdnf, Sirt1, and Psen1 is not regulated by promoter methylation in Alzheimer's disease patients 110
Alterations in prodynorphin gene expression in 6-OHDA lesioned rat brain. 107
Early-life nicotine or cotinine exposure produces long-lasting sleep alterations and downregulation of hippocampal corticosteroid receptors in adult mice 105
Targeting the JAK/STAT Pathway: A Combined Ligand- And Target-Based Approach 104
Effects of acute ethanol exposure on class I HDACs family enzymes in wild-type and BDNF(+/-) mice 103
The standardized Withania somnifera Dunal root extract alters basal and morphine-induced opioid receptor gene expression changes in neuroblastoma cells. 103
Nociceptin/orphanin FQ prevents the antinociceptive action of paracetamol on the rat hot plate test. 102
EFFECTS OF 3,4-METHYLENDIOXY-N-METHYLAMPHETAMINE (MDMA, ‘ECSTASY’) ADMINISTRATION ON THE DYNORPHINERGIC SYSTEM IN THE RAT BRAIN. 101
A new potent analgesic agent with reduced liability to produce morphine tolerance 101
Human apolipoprotein E4 modulates the expression of Pin1, Sirtuin 1, and Presenilin 1 in brain regions of targeted replacement apoE mice 100
Effects of prolonged treatment with the opiate tramadol on prodynorphin gene expression in rat CNS. 99
Opioid Receptor Gene Expression in Human Neuroblastoma SH-SY5Y Cells Following Tapentadol Exposure 99
Cocaine affects NOP receptor gene expression in SH-SY5Y cells 98
Alcohol exposures induce selective alterations on endogenous opioid system genes regulation in rat amygdala: possible epigenetic mechanisms 97
NOP receptor antagonism reduces alcohol drinking in male and female rats through mechanisms involving the central amygdala and ventral tegmental area 96
Nociceptin levels in the CSF of chronic pain patients with or without intrathecal administration of morphine. 95
Regulation of opioid gene expression in the rat brainstem by 3,4-methylenedioxymethamphetamine (MDMA): role of serotonin and involvement of CREB and ERK cascade. 95
Role of serotonin in the regulation of the dynorphinergic system by a kappa-opioid agonist and cocaine treatment in rat CNS. 94
Transcriptional and epigenetic phenomena in peripheral blood cells of monozygotic twins discordant for alzheimer's disease, a case report 94
Alterations of the dynorphinergic system during tolerance development in rat brain by novel opioid compounds 93
Regulation of the genes encoding the ppN/OFQ and NOP receptor 93
Selective DNA methylation of BDNF promoter in bipolar disorder: differences among patients with BDI and BDII. 92
Effects of the selective norepinephrine uptake inhibitor nisoxetine on prodynorphin gene expression in rat CNS 92
On the toxicity of e-cigarettes consumption: Focus on pathological cellular mechanisms 90
Possibile role of NOCICEPTIN/OFQ-NOP system in experimental models of Parkinson disease, 90
Interplay between the endogenous opioid system and proteasome complex: Beyond signaling 89
Delta9-tetrahydrocannabinol down regulates NOP receptor gene expression in SH-SY5Y cells 88
ROLE OF DIFFERENT NEUROTRANSMITTERS ON COCAINE-MEDIATED EFFECTS ON PRODYNORPHIN GENE EXPRESSION AND CREB ACTIVATION IN THE RAT BRAIN. 88
Nociceptive responses in melatonin MT2 receptor knockout mice compared to MT1 and double MT1/MT2 receptor knockout mice 88
Investigation on DNA methylation status of opioid peptides promoters in PBMCs of subjects with bipolar disorder 86
Modulation of nociceptin/NOP system by delta9-THC in SH-SY5Y cell line 85
A role for epigenetic mechanisms in the regulation of prodynorphin expression by alcohol 85
Modulation of the negative affective dimension of pain: Focus on selected neuropeptidergic system contributions 84
Evidence of a PPARγ-mediated mechanism in the ability of Withania somnifera to attenuate tolerance to the antinociceptive effects of morphine 84
The prolonged buprenorphine administration reduces the NOP receptor density in rat cerebral areas 83
Different impact of chronic tramadol or morphine on prodynorphin gene expression 83
Regulation of NOP receptor density by delta-9-tetrahydrocannabinol treatment in SH-SY5Y cells. 83
INVOLVEMENT OF SEROTONIN IN DYNORPHINERGIC SYSTEM REGULATION BY KAPPA-OPIOID AGONIST AND COCAINE TREATMENTS 83
Chronic Trazodone and Citalopram Treatments Increase Trophic Factor and Circadian Rhythm Gene Expression in Rat Brain Regions Relevant for Antidepressant Efficacy 82
Ethanol and acetaldehyde exposure induces specific epigenetic modifications in the prodynorphin gene promoter in a human neuroblastoma cell line. 82
Dysregulation of nociceptin/orphanin fq and dynorphin systems in the extended amygdala of alcohol preferring marchigian sardinian (Msp) rats 82
Cross-talk between CB1 and NOP receptors in human neuroblastoma SH-SY5Y cells 79
An Exploratory Pilot Study of Changes in Global DNA Methylation in Patients Undergoing Major Breast Surgery Under Opioid-Based General Anesthesia 79
Nociceptin Modulates Bronchoconstriction Induced by Sensory Nerve Activation in Mouse Lung. 78
Pharmacology of opiate analgesics for chronic pain management - La gestione del dolore cronico: Farmacologia degli analgesici oppiacei 76
Il Sistema Oppioide 74
Short-term withdrawal from repeated exposure to cocaine during adolescence modulates dynorphin mRNA levels and BDNF signaling in the rat nucleus accumbens 73
Pin1 contribution to Alzheimer's disease: transcriptional and epigenetic mechanisms in patients with late-onset Alzheimer's disease. 72
NOP receptor density is reduced by chronic infusion with buprenorphine in selected rat brain areas. 71
Selective DNA methylation of BDNF promoter in bipolar disorder 70
Safe use of opioids in chronic kidney disease and hemodialysis patients: Tips and tricks for non-pain specialists 70
Interplay between prokineticins and histone demethylase kdm6a in a murine model of bortezomib-induced neuropathy 70
Cura degli Atti del Convegno Monotematico SIF "Neurofarmacologia e Neurobiologia delle Dipendenze" 69
Supraspinal melatonin MT2 receptor agonism alleviates pain via a neural circuit that recruits mu opioid receptors 68
Tapentadol: An analgesic that differs from classic opioids due to its noradrenergic mechanism of action 65
Fentanyl citrate sublingual formulation (Vellofent®) for quick BTcP hindering 64
Activation of Antioxidant and Proteolytic Pathways in the Nigrostriatal Dopaminergic System After 3,4-Methylenedioxymethamphetamine Administration: Sex-Related Differences 64
Nociceptive behavior and central neuropeptidergic dysregulations in male and female mice of a Fabry disease animal model 63
Effects of unburned tobacco smoke on inflammatory and oxidative mediators in the rat prefrontal cortex 59
Early social isolation differentially affects the glucocorticoid receptor system and alcohol-seeking behavior in male and female Marchigian Sardinian alcohol-preferring rats 46
Current and Future Therapeutic Options in Pain Management: Multi-mechanistic Opioids Involving Both MOR and NOP Receptor Activation 43
Unburned Tobacco Smoke Affects Neuroinflammation-Related Pathways in the Rat Mesolimbic System. 36
Effects of Different Opioid Drugs on Oxidative Status and Proteasome Activity in SH-SY5Y Cells 36
Sex-dependent effect of inflammatory pain on negative affective states is prevented by kappa opioid receptors blockade in the nucleus accumbens shell 35
Outcomes of early social experiences on glucocorticoid and endocannabinoid systems in the prefrontal cortex of male and female adolescent rats 23
Studies on the antinociceptive effect of intrathecal salmon calcitonin 20
Alterations in neuroinflammation-related pathways induced by unburned tobacco smoke in the rat mesolimbic system 15
Distinguishable effects of intrathecal dynorphins, somatostatin, neurotensin and s-calcitonin on nociception and motor function in the rat 14
Totale 10.686
Categoria #
all - tutte 27.933
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 27.933


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201.518 0 0 0 0 0 212 228 322 332 178 71 175
2020/20211.469 243 136 62 70 48 42 53 86 120 98 110 401
2021/20221.515 160 66 102 88 144 100 78 143 53 48 252 281
2022/20231.958 188 272 78 221 124 180 71 113 396 45 190 80
2023/2024896 51 115 55 89 60 128 41 47 55 84 85 86
2024/20251.826 212 426 269 237 541 141 0 0 0 0 0 0
Totale 10.745