CRIS Current Research Information System

ZANNA, CLAUDIA
 Distribuzione geografica
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Continente #
NA - Nord America 2.817
EU - Europa 2.389
AS - Asia 1.013
AF - Africa 139
OC - Oceania 6
SA - Sud America 4
Totale 6.368
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Nazione #
US - Stati Uniti d'America 2.809
GB - Regno Unito 566
IT - Italia 553
CN - Cina 375
SE - Svezia 333
DE - Germania 302
VN - Vietnam 279
UA - Ucraina 176
SG - Singapore 150
IN - India 114
FR - Francia 96
IE - Irlanda 91
RU - Federazione Russa 83
JO - Giordania 47
TG - Togo 47
EE - Estonia 41
ZA - Sudafrica 40
CH - Svizzera 35
CI - Costa d'Avorio 34
BG - Bulgaria 23
SC - Seychelles 17
FI - Finlandia 15
BE - Belgio 14
JP - Giappone 13
ID - Indonesia 11
GR - Grecia 9
CA - Canada 8
AT - Austria 7
NL - Olanda 7
AU - Australia 6
CZ - Repubblica Ceca 6
HR - Croazia 6
IR - Iran 6
HK - Hong Kong 5
RO - Romania 5
DK - Danimarca 4
ES - Italia 4
PK - Pakistan 4
LB - Libano 3
SK - Slovacchia (Repubblica Slovacca) 3
BR - Brasile 2
NO - Norvegia 2
PE - Perù 2
PL - Polonia 2
SI - Slovenia 2
AE - Emirati Arabi Uniti 1
BD - Bangladesh 1
HU - Ungheria 1
KR - Corea 1
LT - Lituania 1
LU - Lussemburgo 1
MN - Mongolia 1
NG - Nigeria 1
PT - Portogallo 1
TR - Turchia 1
TW - Taiwan 1
Totale 6.368
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Città #
Southend 503
Chandler 312
Fairfield 298
Ashburn 232
Ann Arbor 171
Bologna 168
Wilmington 147
Woodbridge 142
Seattle 140
Singapore 129
Houston 128
Jacksonville 118
Dong Ket 115
Princeton 115
Cambridge 93
Dublin 89
Padova 52
Westminster 52
Amman 47
Lomé 47
Turin 41
Nanjing 40
Redmond 40
Berlin 38
Redwood City 37
New York 36
Abidjan 34
Jinan 34
Bern 32
Milan 31
Santa Clara 30
Saint Petersburg 29
Medford 23
Mülheim 22
Sofia 22
Warrington 21
Changsha 20
Shenyang 17
Beijing 16
Boardman 16
Hebei 16
Los Angeles 16
Dearborn 15
Florence 15
San Diego 15
Shanghai 15
Tianjin 15
Brussels 14
Doylestown 14
Mahé 14
Guangzhou 13
Kuban 13
Nanchang 13
Rome 13
Haikou 12
Jakarta 11
Des Moines 10
Helsinki 10
Olalla 10
Tokyo 10
Hangzhou 9
Norwalk 9
Taiyuan 9
Taizhou 9
Zhengzhou 9
London 8
Verona 8
Ancona 7
Falls Church 7
Shenzhen 7
Boydton 6
Fuzhou 6
Jiaxing 6
Ningbo 6
Paris 6
Phoenix 6
Forlì 5
Livorno 5
Lynchburg 5
Modena 5
Munich 5
Naples 5
Ponte San Pietro 5
Argelato 4
Botticino 4
Hefei 4
Hong Kong 4
Hyderabad 4
Lappeenranta 4
Olomouc 4
Berkeley 3
Boston 3
Bovolone 3
Bratislava 3
Bühl 3
Catania 3
Chengdu 3
Frankfurt Am Main 3
Frankfurt am Main 3
Fremont 3
Totale 4.152
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Nome #
Coenzyme Q biosynthesis inhibition induces HIF-1α stabilization and metabolic switch toward glycolysis 200
A clinically complex form of dominant optic atrophy (OPA8) maps on chromosome 16. 196
'Behr syndrome' with OPA1 compound heterozygote mutations 189
Alterations in the supramolecular interactions of respiratory chain complexes and enhanced superoxide production by the cytochrome b Y278C mutation which causes a multisystem disorder 166
Peculiar combinations of individually non-pathogenic missense mitochondrial DNA variants cause low penetrance Leber's hereditary optic neuropathy 161
Apoptosis induced by staurosporine in ECV304 cells requires cell shrinkage and upregulation of Cl- conductance 159
The antioxidant function of Bcl-2 preserves cytoskeletal stability of cells with defective respiratory complex I. 159
The background of mitochondrial DNA haplogroup J increases the sensitivity of Leber's hereditary optic neuropathy cells to 2,5-hexanedione toxicity. 157
DNMT1 mutations leading to neurodegeneration paradoxically reflect on mitochondrial metabolism 156
Deciphering OPA1 mutations pathogenicity by combined analysis of human, mouse and yeast cell models 150
Mitochondrial abnormalities in fibroblasts carrying DNMT1 mutations 148
Eight human OPA1 isoforms, long and short: What are they for? 145
Caspase-independent death of Leber's hereditary optic neuropathy cybrids is driven by energetic failure and mediated by AIF and Endonuclease G. 142
Genetic Basis of Mitochondrial Optic Neuropathies. 141
pH difference across the outer mitochondrial membrane measured with a green fluorescent protein mutant 138
Cybrid studies establish the causal link between the mtDNA m.3890G>A/MT-ND1 mutation and optic atrophy with bilateral brainstem lesions. 135
Cell death of fibroblasts derived from patients with Leber’s hereditary optic neuropathy mtDNA mutations 133
ATP depletion and caspase independent death of cybrids bearing Leber's Hereditary Optic neuropathy MTDNA mutations incubated in galactose medium. A model for endonuclease G-mediated apoptosis 131
OPA1 Isoforms in the Hierarchical Organization of Mitochondrial Functions 131
The cytochrome B p.278Y>C mutation causative of a multisystem disorder enhances superoxide production and alters supramolecular interactions of respiratory chain complexes 126
Effect of energetic stress and the ceramide analogue C6-ceramide on thyroid oncocytoma cell lines. 118
Bioenergetics shapes cellular death pathways in Leber’s hereditary optic neuropathy: a model of mitochondrial neurodegeneration 118
AIF and endonuclease G are involved in the caspase-indepenent death of cybrids with LHON mutations 117
OPA1: how much do we know to approach therapy? 117
Mutations in SLC25A46, encoding a UGO1-like protein, cause an optic atrophy spectrum disorder 115
Syndromic parkinsonism and dementia associated with OPA1 missense mutations 113
Evaluation of the energetic efficiency of cells derived from patients with dominant optic neuropathy (DOA). 110
Protection against oxidant-induced apoptosis by exogenous glutathione in Leber Hereditary Optic Neuropathy cybrids. 110
Metabolomics hallmarks OPA1 variants correlating with their in-vitro phenotype and predicting clinical severity 110
Effect of energetic stress and the ceramide analogue C6-ceramide on thyroid oncocytoma cell lines 109
Rare mtDNA variants in Leber hereditary optic neuropathy families with recurrence of myoclonus. 108
OPA 1 mutations induce mitochondrial DNA instability and optic atrophy "plus" phenotypes 108
Drug repositioning as a therapeutic strategy for neurodegenerations associated with OPA1 mutations 107
Mitochondria: Biogenesis and mitophagy balance in segregation and clonal expansion of mitochondrial DNA mutations 104
Determination of mitochondrial fusion in fibroblasts from dominant optic atrophy patients bearing the c.2708delttag OPA1 mutation 103
OPA3, a new regulator of mitochondrial fission? 102
OPA 1 mutations associated with dominant optic atrophy impair oxidative phosphorylation and mitochondrial fusion. 100
SSBP1 mutations cause mtDNA depletion underlying a complex optic atrophy disorder 100
Effect of energetic stress and the ceramide analogue C6-ceramide on thyroid oncocytoma cell lines 97
Why mitochondria must fuse to maintain their genome integrity 95
OPA1 Links Human Mitochondrial Genome Maintenance to mtDNA Replication and Distribution 93
Dominant optic neuropathy: analysis of the energetic efficiency and mitochondrial dynamics 92
DNA methyltransferase 1 mutations and mitochondrial pathology: Is mtDNA methylated? 92
Cybrids with mtDNA mutations causing Leber’s hereditary optic neuropathy are sensitized to apoptotic death induced by a mitochondrial oxidative stress 92
Severe defect of complex I-dependent ATP synthesis shapes the mitochondria-driven path of apoptotic cell death in Leber’s Hereditary Optic Neuropathy. 85
Validation of a MGM1/OPA1 chimeric gene for functional analysis in yeast of mutations associated with dominant optic atrophy 85
Fine-tuning of the respiratory complexes stability and supercomplexes assembly in cells defective of complex III 83
OPA1 directly interacts with respiratory complexes and AIF. 78
Energetic efficiency and mitochondrial dynamics in fibroblasts derived from patients with optic neuropathies. 75
Oxidative phosphorylation dysfunction in fibroblasts bearing different pathological OPA1 mutations. 74
OPA3 IS AN INNER MITOCHONDRIAL MEMBRANE PROTEIN INVOLVED IN MITOCHONDRIAL DYNAMICS REGULATION 74
Impairment of mitochondrial fusion in dominant optic atrophy, a model for selective neurodegeneration 70
Functional investigation of the mitochondrial protein OPA3 69
Respiratory Chain Function and Mitochondrial Dynamics in Leber's Hereditary Optic Neuropathy (LHON) and OPA1-Related Dominant Optic Atrophy (DOA) Fibroblasts. 64
Genetic variants affecting NQO1 protein levels impact the efficacy of idebenone treatment in Leber hereditary optic neuropathy 63
Organization of the respiratory supercomplexes in cells with defective complex III: Structural features and metabolic consequences 57
Pathological mitophagy disrupts mitochondrial homeostasis in Leber's hereditary optic neuropathy 50
The Pro-Oncogenic Protein IF1 Promotes Proliferation of Anoxic Cancer Cells during Re-Oxygenation 35
OPA1 mutations induce mitochondrial DNA instability and optic atrophy plus phenotypes 2
Totale 6.557
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Categoria #
all - tutte 16.279
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 16.279
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201.170 0 0 0 80 121 132 140 211 215 98 55 118
2020/2021985 172 65 20 52 23 60 29 69 62 58 53 322
2021/20221.257 90 52 77 77 108 50 52 91 50 152 258 200
2022/20231.382 140 221 81 161 72 104 48 85 237 33 121 79
2023/2024467 21 55 13 35 29 91 22 35 24 77 35 30
2024/2025424 67 167 118 72 0 0 0 0 0 0 0 0
Totale 6.557