ZANNA, CLAUDIA
ZANNA, CLAUDIA
DIPARTIMENTO DI SCIENZE BIOMEDICHE E NEUROMOTORIE
Ricercatori a tempo determinato
'Behr syndrome' with OPA1 compound heterozygote mutations
2015 Carelli, Valerio; Sabatelli, Mario; Carrozzo, Rosalba; Rizza, Teresa; Schimpf, Simone; Wissinger, Bernd; Zanna, Claudia; Rugolo, Michela; La Morgia, Chiara; Caporali, Leonardo; Carbonelli, Michele; Barboni, Piero; Tonon, Caterina; Lodi, Raffaele; Bertini, Enrico
A clinically complex form of dominant optic atrophy (OPA8) maps on chromosome 16.
2011 Carelli V.; Schimpf S.; Fuhrmann N.; Valentino M.L.; Zanna C.; Iommarini L.; Papke M.; Schaich S.; Tippmann S.; Baumann B.; Barboni P.; Longanesi L.; Rugolo M.; Ghelli A.; Alavi M.V.; Youle R.J.; Bucchi L.; Carroccia R.; Giannoccaro M.P.; Tonon C.; Lodi R.; Cenacchi G.; Montagna P.; Liguori R.; Wissinger B.
AIF and endonuclease G are involved in the caspase-indepenent death of cybrids with LHON mutations
2004 A.M.Porcelli; C. Zanna; A. Montanaro; V.Carelli; A.Ghelli; M.Rugolo
Alterations in the supramolecular interactions of respiratory chain complexes and enhanced superoxide production by the cytochrome b Y278C mutation which causes a multisystem disorder
2012 Ghelli A.; Tropeano C.V.; Calvaruso M.A.; Marchesini A.; Iommarini L.; Porcelli A.M.; Zanna C.; Gasparre G.; Kurelac I.; De Nardo V.; Martinuzzi A.; Vissing J.; Selamoglu N.; Daldal F.; Rugolo M.
Apoptosis induced by staurosporine in ECV304 cells requires cell shrinkage and upregulation of Cl- conductance
2004 A.M. PORCELLI; A. GHELLI; C. ZANNA; P. VALENTE; S. FERRONI; M. RUGOLO
ATP depletion and caspase independent death of cybrids bearing Leber's Hereditary Optic neuropathy MTDNA mutations incubated in galactose medium. A model for endonuclease G-mediated apoptosis
2004 A. Ghelli; C. Zanna; A.M. Porcelli; V. Carelli; M. Rugolo
Bioenergetics shapes cellular death pathways in Leber’s hereditary optic neuropathy: a model of mitochondrial neurodegeneration
2004 CARELLI V; RUGOLO M; SGARBI G; GHELLI A; ZANNA C; BARACCA A; LENAZ G; NAPOLI E; MARTINUZZI A; SOLAINI G.
Caspase-independent death of Leber's hereditary optic neuropathy cybrids is driven by energetic failure and mediated by AIF and Endonuclease G.
2005 ZANNA C.; GHELLI A.; PORCELLI AM.; MARTINUZZI A.; Carelli V.; RUGOLO M.
Cell death of fibroblasts derived from patients with Leber’s hereditary optic neuropathy mtDNA mutations
2004 C.Zanna; A.M.Porcelli; A.Ghelli; V.Carelli; A.Martinuzzi; M.Rugolo
Coenzyme Q biosynthesis inhibition induces HIF-1α stabilization and metabolic switch toward glycolysis
2021 Liparulo, Irene; Bergamini, Christian; Bortolus, Marco; Calonghi, Natalia; Gasparre, Giuseppe; Kurelac, Ivana; Masin, Luca; Rizzardi, Nicola; Rugolo, Michela; Wang, Wenping; Aleo, Serena J; Kiwan, Alisar; Torri, Cristian; Zanna, Claudia; Fato, Romana
Cybrid studies establish the causal link between the mtDNA m.3890G>A/MT-ND1 mutation and optic atrophy with bilateral brainstem lesions.
2013 Caporali L;Ghelli AM;Iommarini L;Maresca A;Valentino ML;La Morgia C;Liguori R;Zanna C;Barboni P;De Nardo V;Martinuzzi A;Rizzo G;Tonon C;Lodi R;Calvaruso MA;Cappelletti M;Porcelli AM;Achilli A;Pala M;Torroni A;Carelli V
Cybrids with mtDNA mutations causing Leber’s hereditary optic neuropathy are sensitized to apoptotic death induced by a mitochondrial oxidative stress
2006 A. M. Ghelli; C. Zanna; V. Carelli; A. Martinuzzi; M. Rugolo
Deciphering OPA1 mutations pathogenicity by combined analysis of human, mouse and yeast cell models
2018 Del Dotto, Valentina; Fogazza, Mario; Musiani, Francesco; Maresca, Alessandra; Aleo, Serena J.; Caporali, Leonardo; La Morgia, Chiara; Nolli, Cecilia; Lodi, Tiziana; Goffrini, Paola; Chan, David; Carelli, Valerio; Rugolo, Michela; Baruffini, Enrico; Zanna, Claudia*
Determination of mitochondrial fusion in fibroblasts from dominant optic atrophy patients bearing the c.2708delttag OPA1 mutation
2006 C. Zanna; A. Ghelli; A. M.Porcelli; M. Karbowski; R.J. Youle; V. Carelli; M. Rugolo
DNA methyltransferase 1 mutations and mitochondrial pathology: Is mtDNA methylated?
2015 Maresca, Alessandra; Zaffagnini, Mirko; Caporali, Leonardo; Carelli, Valerio; Zanna, Claudia
DNMT1 mutations leading to neurodegeneration paradoxically reflect on mitochondrial metabolism
2020 Maresca, Alessandra; Del Dotto, Valentina; Capristo, Mariantonietta; Scimonelli, Emanuela; Tagliavini, Francesca; Morandi, Luca; Tropeano, Concetta Valentina; Caporali, Leonardo; Mohamed, Susan; Roberti, Marina; Scandiffio, Letizia; Zaffagnini, Mirko; Rossi, Jacopo; Cappelletti, Martina; Musiani, Francesco; Contin, Manuela; Riva, Roberto; Liguori, Rocco; Pizza, Fabio; La Morgia, Chiara; Antelmi, Elena; Polosa, Paola Loguercio; Mignot, Emmanuel; Zanna, Claudia; Plazzi, Giuseppe; Carelli, Valerio
Dominant optic neuropathy: analysis of the energetic efficiency and mitochondrial dynamics
2005 M.Rugolo; C.Zanna; A.Ghelli; A.M.Porcelli; V.Carelli
Drug repositioning as a therapeutic strategy for neurodegenerations associated with OPA1 mutations
2020 Aleo, Serena J; Del Dotto, Valentina; Fogazza, Mario; Maresca, Alessandra; Lodi, Tiziana; Goffrini, Paola; Ghelli, Anna; Rugolo, Michela; Carelli, Valerio; Baruffini, Enrico; Zanna, Claudia
Effect of energetic stress and the ceramide analogue C6-ceramide on thyroid oncocytoma cell lines.
2005 A. M. Porcelli; A. Ghelli; L. Iommarini; M. Hoque; C. Zanna; V. Carelli; G.Romeo; M. Rugolo
Effect of energetic stress and the ceramide analogue C6-ceramide on thyroid oncocytoma cell lines
2005 A.M. Porcelli; A. Ghelli; L. Iommarini; M. Hoque; C. Zanna; V. Carelli; G. Romeo; M. Rugolo
| Titolo | Autore(i) | Anno | Periodico | Editore | Tipo | File |
|---|---|---|---|---|---|---|
| 'Behr syndrome' with OPA1 compound heterozygote mutations | Carelli, Valerio; Sabatelli, Mario; Carrozzo, Rosalba; Rizza, Teresa; Schimpf, Simone; Wissinger,... Bernd; Zanna, Claudia; Rugolo, Michela; La Morgia, Chiara; Caporali, Leonardo; Carbonelli, Michele; Barboni, Piero; Tonon, Caterina; Lodi, Raffaele; Bertini, Enrico | 2015-01-01 | BRAIN | - | 1.01 Articolo in rivista | - |
| A clinically complex form of dominant optic atrophy (OPA8) maps on chromosome 16. | Carelli V.; Schimpf S.; Fuhrmann N.; Valentino M.L.; Zanna C.; Iommarini L.; Papke M.; Schaich S....; Tippmann S.; Baumann B.; Barboni P.; Longanesi L.; Rugolo M.; Ghelli A.; Alavi M.V.; Youle R.J.; Bucchi L.; Carroccia R.; Giannoccaro M.P.; Tonon C.; Lodi R.; Cenacchi G.; Montagna P.; Liguori R.; Wissinger B. | 2011-01-01 | HUMAN MOLECULAR GENETICS | - | 1.01 Articolo in rivista | - |
| AIF and endonuclease G are involved in the caspase-indepenent death of cybrids with LHON mutations | A.M.Porcelli; C. Zanna; A. Montanaro; V.Carelli; A.Ghelli; M.Rugolo | 2004-01-01 | - | s.n | 4.02 Riassunto (Abstract) | - |
| Alterations in the supramolecular interactions of respiratory chain complexes and enhanced superoxide production by the cytochrome b Y278C mutation which causes a multisystem disorder | Ghelli A.; Tropeano C.V.; Calvaruso M.A.; Marchesini A.; Iommarini L.; Porcelli A.M.; Zanna C.; G...asparre G.; Kurelac I.; De Nardo V.; Martinuzzi A.; Vissing J.; Selamoglu N.; Daldal F.; Rugolo M. | 2012-01-01 | BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS | - | 4.02 Riassunto (Abstract) | - |
| Apoptosis induced by staurosporine in ECV304 cells requires cell shrinkage and upregulation of Cl- conductance | A.M. PORCELLI; A. GHELLI; C. ZANNA; P. VALENTE; S. FERRONI; M. RUGOLO | 2004-01-01 | CELL DEATH AND DIFFERENTIATION | - | 1.01 Articolo in rivista | - |
| ATP depletion and caspase independent death of cybrids bearing Leber's Hereditary Optic neuropathy MTDNA mutations incubated in galactose medium. A model for endonuclease G-mediated apoptosis | A. Ghelli; C. Zanna; A.M. Porcelli; V. Carelli; M. Rugolo | 2004-01-01 | - | Dipartimento Biologia Ev. SP. | 4.02 Riassunto (Abstract) | - |
| Bioenergetics shapes cellular death pathways in Leber’s hereditary optic neuropathy: a model of mitochondrial neurodegeneration | CARELLI V; RUGOLO M; SGARBI G; GHELLI A; ZANNA C; BARACCA A; LENAZ G; NAPOLI E; MARTINUZZI A; SOL...AINI G. | 2004-01-01 | BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS | - | 1.01 Articolo in rivista | - |
| Caspase-independent death of Leber's hereditary optic neuropathy cybrids is driven by energetic failure and mediated by AIF and Endonuclease G. | ZANNA C.; GHELLI A.; PORCELLI AM.; MARTINUZZI A.; Carelli V.; RUGOLO M. | 2005-01-01 | APOPTOSIS | - | 1.01 Articolo in rivista | - |
| Cell death of fibroblasts derived from patients with Leber’s hereditary optic neuropathy mtDNA mutations | C.Zanna; A.M.Porcelli; A.Ghelli; V.Carelli; A.Martinuzzi; M.Rugolo | 2004-01-01 | - | s.n | 4.02 Riassunto (Abstract) | - |
| Coenzyme Q biosynthesis inhibition induces HIF-1α stabilization and metabolic switch toward glycolysis | Liparulo, Irene; Bergamini, Christian; Bortolus, Marco; Calonghi, Natalia; Gasparre, Giuseppe; Ku...relac, Ivana; Masin, Luca; Rizzardi, Nicola; Rugolo, Michela; Wang, Wenping; Aleo, Serena J; Kiwan, Alisar; Torri, Cristian; Zanna, Claudia; Fato, Romana | 2021-01-01 | THE FEBS JOURNAL | - | 1.01 Articolo in rivista | - |
| Cybrid studies establish the causal link between the mtDNA m.3890G>A/MT-ND1 mutation and optic atrophy with bilateral brainstem lesions. | Caporali L;Ghelli AM;Iommarini L;Maresca A;Valentino ML;La Morgia C;Liguori R;Zanna C;Barboni P;D...e Nardo V;Martinuzzi A;Rizzo G;Tonon C;Lodi R;Calvaruso MA;Cappelletti M;Porcelli AM;Achilli A;Pala M;Torroni A;Carelli V | 2013-01-01 | BIOCHIMICA ET BIOPHYSICA ACTA. MOLECULAR BASIS OF DISEASE | - | 1.01 Articolo in rivista | - |
| Cybrids with mtDNA mutations causing Leber’s hereditary optic neuropathy are sensitized to apoptotic death induced by a mitochondrial oxidative stress | A. M. Ghelli; C. Zanna; V. Carelli; A. Martinuzzi; M. Rugolo | 2006-01-01 | - | s.n | 4.02 Riassunto (Abstract) | - |
| Deciphering OPA1 mutations pathogenicity by combined analysis of human, mouse and yeast cell models | Del Dotto, Valentina; Fogazza, Mario; Musiani, Francesco; Maresca, Alessandra; Aleo, Serena J.; C...aporali, Leonardo; La Morgia, Chiara; Nolli, Cecilia; Lodi, Tiziana; Goffrini, Paola; Chan, David; Carelli, Valerio; Rugolo, Michela; Baruffini, Enrico; Zanna, Claudia* | 2018-01-01 | BIOCHIMICA ET BIOPHYSICA ACTA. MOLECULAR BASIS OF DISEASE | - | 1.01 Articolo in rivista | 56_2018_DelDotto_BBAMolBasisDisease.pdf |
| Determination of mitochondrial fusion in fibroblasts from dominant optic atrophy patients bearing the c.2708delttag OPA1 mutation | C. Zanna; A. Ghelli; A. M.Porcelli; M. Karbowski; R.J. Youle; V. Carelli; M. Rugolo | 2006-01-01 | - | s. n. | 4.02 Riassunto (Abstract) | - |
| DNA methyltransferase 1 mutations and mitochondrial pathology: Is mtDNA methylated? | Maresca, Alessandra; Zaffagnini, Mirko; Caporali, Leonardo; Carelli, Valerio; Zanna, Claudia | 2015-01-01 | FRONTIERS IN GENETICS | - | 1.01 Articolo in rivista | Dna Methyltransferase 1 Mutations and Mitochondrial Pathology.pdf |
| DNMT1 mutations leading to neurodegeneration paradoxically reflect on mitochondrial metabolism | Maresca, Alessandra; Del Dotto, Valentina; Capristo, Mariantonietta; Scimonelli, Emanuela; Taglia...vini, Francesca; Morandi, Luca; Tropeano, Concetta Valentina; Caporali, Leonardo; Mohamed, Susan; Roberti, Marina; Scandiffio, Letizia; Zaffagnini, Mirko; Rossi, Jacopo; Cappelletti, Martina; Musiani, Francesco; Contin, Manuela; Riva, Roberto; Liguori, Rocco; Pizza, Fabio; La Morgia, Chiara; Antelmi, Elena; Polosa, Paola Loguercio; Mignot, Emmanuel; Zanna, Claudia; Plazzi, Giuseppe; Carelli, Valerio | 2020-01-01 | HUMAN MOLECULAR GENETICS ONLINE | - | 1.01 Articolo in rivista | ddaa014.pdf; supplementary_materials_rev_ddaa014.docx |
| Dominant optic neuropathy: analysis of the energetic efficiency and mitochondrial dynamics | M.Rugolo; C.Zanna; A.Ghelli; A.M.Porcelli; V.Carelli | 2005-01-01 | ITALIAN JOURNAL OF BIOCHEMISTRY | - | 4.02 Riassunto (Abstract) | - |
| Drug repositioning as a therapeutic strategy for neurodegenerations associated with OPA1 mutations | Aleo, Serena J; Del Dotto, Valentina; Fogazza, Mario; Maresca, Alessandra; Lodi, Tiziana; Goffrin...i, Paola; Ghelli, Anna; Rugolo, Michela; Carelli, Valerio; Baruffini, Enrico; Zanna, Claudia | 2020-01-01 | HUMAN MOLECULAR GENETICS | - | 1.01 Articolo in rivista | 2021 - Aleo et al HMG.pdf; supplementary_material_19-10-20_ddaa244.docx |
| Effect of energetic stress and the ceramide analogue C6-ceramide on thyroid oncocytoma cell lines. | A. M. Porcelli; A. Ghelli; L. Iommarini; M. Hoque; C. Zanna; V. Carelli; G.Romeo; M. Rugolo | 2005-01-01 | - | s.n | 4.02 Riassunto (Abstract) | - |
| Effect of energetic stress and the ceramide analogue C6-ceramide on thyroid oncocytoma cell lines | A.M. Porcelli; A. Ghelli; L. Iommarini; M. Hoque; C. Zanna; V. Carelli; G. Romeo; M. Rugolo | 2005-01-01 | - | Dipartimento di Biologia Ev. Sp. | 4.02 Riassunto (Abstract) | - |