TONETTI, TOMMASO
TONETTI, TOMMASO
DIMEC - DIPARTIMENTO DI SCIENZE MEDICHE E CHIRURGICHE
Docenti di ruolo di IIa fascia
Aggressive joint pharmacokinetic/pharmacodynamic target attainment of TDM-guided continuous infusion meropenem-vaborbactam monotherapy: a valuable strategy for maximizing the microbiological outcome of documented KPC-producing Enterobacterales infections?
2026 Gatti, Milo; Bonazzetti, Cecilia; Secci, Benedetta; Giorgi, Beatrice; Rinaldi, Matteo; Cojutti, Pier Giorgio; Ambretti, Simone; Siniscalchi, Antonio; Tonetti, Tommaso; Viale, Pierluigi; Pea, Federico
Contemporary local anaesthetic-associated adverse events and mortality: searching for the root causes of the pharmacovigilance signal. Br J Anaesth 2026;136:411–13
2026 Raschi, E.; Tonetti, T.; Khouri, C.; Poluzzi, E.; De Ponti, F.
Lung recruitability determines the impact of PEEP on mechanical power in ARDS
2026 Grieco, Domenico L.; Collino, Francesca; Steinberg, Irene; Pintaudi, Gabriele; Dell'Anna, Antonio M.; Busana, Mattia; Pesenti, Antonio; Rocco, Patricia R. M.; Camporota, Luigi; Antonelli, Massimo; Tonetti, Tommaso
Regional anesthesia in breast surgery: An Italian expert consensus – Part 1: Methodology and Delphi strategy
2026 Santonastaso, Domenico P.; De Cassai, Alessandro; Pilia, Eros; Coppolino, Francesco; Melegari, Gabriele; Piccioni, Federico; Fattorini, Fabrizio; Tognù, Andrea; Sepolvere, Giuseppe; Scimia, Paolo; Curcio, Annalisa; Bagaphou, Claude T.; Coviello, Antonio; Morelli, Alessandra; Marandola, Diego; Pietrantozzi, Dario; Tedesco, Mario; Gentili, Alessandra; Rispoli, Marco; Lubrano, Giuseppe; Mattiacci, Dario M.; Nespoli, Moana R.; D'Errico, Cristiano; Costa, Fabio; Bizzarri, Federico; Ranieri, Giorgio; Rocco, Nicola; Tonetti, Tommaso; Folli, Secondo; De Chiara, Annabella; Pace, Maria C.; Fusco, Pierfrancesco; Agnoletti, Vanni
A pre-post quasi-experimental study of antimicrobial stewardship exploring the impact of a multidisciplinary approach aimed at attaining an aggressive joint pharmacokinetic/pharmacodynamic target with ceftazidime/avibactam on treatment outcome of KPC-producing Klebsiella pneumoniae infections and on ceftazidime/avibactam resistance development
2025 Gatti, Milo; Rinaldi, Matteo; Cojutti, Pier Giorgio; Bonazzetti, Cecilia; Siniscalchi, Antonio; Tonetti, Tommaso; Ambretti, Simone; Tedeschi, Sara; Giannella, Maddalena; Viale, Pierluigi; Pea, Federico
A pre-post quasi-experimental study of the impact of TDM-guided aggressive pharmacokinetic/pharmacodynamic target attainment of continuous infusion ceftolozane/tazobactam monotherapy in treating severe Pseudomonas aeruginosa infections: A strategy useful for raising the bar?
2025 Gatti, M.; Rinaldi, M.; Bonazzetti, C.; Siniscalchi, A.; Tonetti, T.; Ambretti, S.; Giannella, M.; Viale, P.; Pea, F.
Acute Respiratory Distress Syndrome and Fluid Management: Finding the Perfect Balance
2025 Sbaraini Zernini, Irene; Nocera, Domenico; D'Albo, Rosanna; Tonetti, Tommaso
Continuous positive airway pressure to prevent reintubation in patients recovering from cardiac surgery
2025 Pasero, Daniela; Costamagna, Andrea; Filippini, Claudia; Blangetti, Ilaria; Cattaneo, Sergio; Baiocchi, Massimo; Balata, Andrea; Bottiroli, Maurizio; Dambruoso, Pierpaolo; De Paulis, Stefano; Grazioli, Lorenzo; Locatelli, Alessandro; Lorini, Ferdinando Luca; Mascotti, Alessandra; Mondino, Michele Giovanni; Paparella, Domenico; Salvi, Luca; Tonetti, Tommaso; Tritapepe, Luigi; Ranieri, V. Marco
Generalized Periodic Discharges related to Anaesthesia Withdrawal (GRAWs) after status epilepticus in herpetic encephalitis: when less is more
2025 Asioli, Gian Maria; Urbinati, Giacomo; Tonetti, Tommaso; Guarino, Maria
Keeping the horse with the cart: are we underdosing tazobactam even when using continuous-infusion ceftolozane/tazobactam for effectively preventing resistance development by ESBL-producing Enterobacterales?
2025 Pai, Manjunath P.; Cojutti, Pier Giorgio; Gatti, Milo; Rinaldi, Matteo; Tonetti, Tommaso; Siniscalchi, Antonio; Viale, Pierluigi; Pea, Federico
Mechanical power and VILI: modeling limits and unknowns
2025 Tonetti, T.; Marini, J. J.
Personalizing beta-lactams therapy in critical patients undergoing RRT: moving a further step forward?
2025 Tonetti, Tommaso; Gatti, Milo; Pea, Federico
Reply to Yang and to Xie and Wang
2025 Mascia, L.; Tonetti, T.
Targeting Pseudomonas aeruginosa resistance at the exposure frontier: a population PK/PD blueprint for ceftolozane/tazobactam continuous infusion
2025 Cojutti, Pier Giorgio; Pai, Manjunath P.; Gatti, Milo; Rinaldi, Matteo; Tonetti, Tommaso; Siniscalchi, Antonio; Viale, Pierluigi; Pea, Federico
TDM-Based Approach for Properly Managing Intravenous Isavuconazole Treatment in a Complex Case Mix of Critically Ill Patients
2025 Gatti, Milo; Rinaldi, Matteo; De Paola, Riccardo; Siniscalchi, Antonio; Tonetti, Tommaso; Viale, Pierluigi; Pea, Federico
The role of rapid and advanced microbiological methods in critical care: 2025 Emanuele Russo Delphi consensus
2025 Sambri, Vittorio; Agnoletti, Vanni; Ambretti, Simone; Bartoletti, Michele; Bernaschi, Paola; Bignami, Elena Giovanna; Busani, Stefano; Campoli, Caterina; Carretto, Edoardo; Catena, Fausto; Coloretti, Irene; Cricca, Monica; De Pascale, Gennaro; De Rosa, Francesco Giuseppe; Fontana, Carla; Gherardi, Giovanni; Giannella, Maddalena; Girardis, Massimo; Mancini, Nicasio; Oliva, Alessandra; Podda, Mauro; Piazza, Ornella; Portunato, Federica; Poletti, Venerino; Viceconte, Giulio; Rocchetti, Andrea; Santonastaso, Domenico Pietro; Serapide, Francesca; Stefani, Stefania; Tascini, Carlo; Tebano, Gianpiero; Tosi, Martina; Tumbarello, Mario; Viaggi, Bruno; Viale, Pierluigi; Cristini, Francesco; Bassetti, Matteo; Falcone, Marco; Gentile, Ivan; Gobbi, Luca; Grasselli, Giacomo; Palamara, Anna Teresa; Rossolini, Gianmaria; Russo, Alessandro; Sanguinetti, Maurizio; Sartelli, Massimo; Tonetti, Tommaso
Validation of a predictive risk score of aggressive PK/PD target non-attainment with continuous infusion piperacillin/tazobactam or meropenem in critically ill patients having documented Gram-negative infections
2025 Gatti, Milo; Grimaldi, Pierantonio; Rinaldi, Matteo; Siniscalchi, Antonio; Tonetti, Tommaso; Viale, Pierluigi; Pea, Federico
Association between respiratory distress time and invasive mechanical ventilation in COVID-19 patients: A multicentre regional cohort study
2024 Busani, S; Coloretti, I; Baciarello, M; Bellini, V; Sarti, M; Biagioni, E; Tonelli, R; Marchioni, A; Clini, E; Guaraldi, G; Mussini, C; Meschiari, M; Tonetti, T; Pisani, L; Nava, S; Bignami, E; Ranieri, M V; Girardis, M
Balancing the scales: achieving the optimal beta-lactam to beta-lactamase inhibitor ratio with continuous infusion piperacillin/tazobactam against extended spectrum beta-lactamase producing Enterobacterales
2024 Cojutti, Pier Giorgio; Pai, Manjunath P.; Tonetti, Tommaso; Siniscalchi, Antonio; Viale, Pierluigi; Pea, Federico
Comparative Impact of an Optimized PK/PD Target Attainment of Piperacillin-Tazobactam vs. Meropenem on the Trend over Time of SOFA Score and Inflammatory Biomarkers in Critically Ill Patients Receiving Continuous Infusion Monotherapy for Treating Documented Gram-Negative BSIs and/or VAP
2024 Gatti, Milo; Rinaldi, Matteo; Tonetti, Tommaso; Siniscalchi, Antonio; Viale, Pierluigi; Pea, Federico
| Titolo | Autore(i) | Anno | Periodico | Editore | Tipo | File |
|---|---|---|---|---|---|---|
| Aggressive joint pharmacokinetic/pharmacodynamic target attainment of TDM-guided continuous infusion meropenem-vaborbactam monotherapy: a valuable strategy for maximizing the microbiological outcome of documented KPC-producing Enterobacterales infections? | Gatti, Milo; Bonazzetti, Cecilia; Secci, Benedetta; Giorgi, Beatrice; Rinaldi, Matteo; Cojutti, P...ier Giorgio; Ambretti, Simone; Siniscalchi, Antonio; Tonetti, Tommaso; Viale, Pierluigi; Pea, Federico | 2026-01-01 | INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS | - | 1.01 Articolo in rivista | - |
| Contemporary local anaesthetic-associated adverse events and mortality: searching for the root causes of the pharmacovigilance signal. Br J Anaesth 2026;136:411–13 | Raschi, E.; Tonetti, T.; Khouri, C.; Poluzzi, E.; De Ponti, F. | 2026-01-01 | BRITISH JOURNAL OF ANAESTHESIA | - | 1.04 Replica / breve intervento (e simili) | - |
| Lung recruitability determines the impact of PEEP on mechanical power in ARDS | Grieco, Domenico L.; Collino, Francesca; Steinberg, Irene; Pintaudi, Gabriele; Dell'Anna, Antonio... M.; Busana, Mattia; Pesenti, Antonio; Rocco, Patricia R. M.; Camporota, Luigi; Antonelli, Massimo; Tonetti, Tommaso | 2026-01-01 | CRITICAL CARE | - | 1.01 Articolo in rivista | s13054-026-05843-y.pdf |
| Regional anesthesia in breast surgery: An Italian expert consensus – Part 1: Methodology and Delphi strategy | Santonastaso, Domenico P.; De Cassai, Alessandro; Pilia, Eros; Coppolino, Francesco; Melegari, Ga...briele; Piccioni, Federico; Fattorini, Fabrizio; Tognù, Andrea; Sepolvere, Giuseppe; Scimia, Paolo; Curcio, Annalisa; Bagaphou, Claude T.; Coviello, Antonio; Morelli, Alessandra; Marandola, Diego; Pietrantozzi, Dario; Tedesco, Mario; Gentili, Alessandra; Rispoli, Marco; Lubrano, Giuseppe; Mattiacci, Dario M.; Nespoli, Moana R.; D'Errico, Cristiano; Costa, Fabio; Bizzarri, Federico; Ranieri, Giorgio; Rocco, Nicola; Tonetti, Tommaso; Folli, Secondo; De Chiara, Annabella; Pace, Maria C.; Fusco, Pierfrancesco; Agnoletti, Vanni | 2026-01-01 | SAUDI JOURNAL OF ANAESTHESIA | - | 1.01 Articolo in rivista | regional_anesthesia_in_breast_surgery__an_italian.6.pdf |
| A pre-post quasi-experimental study of antimicrobial stewardship exploring the impact of a multidisciplinary approach aimed at attaining an aggressive joint pharmacokinetic/pharmacodynamic target with ceftazidime/avibactam on treatment outcome of KPC-producing Klebsiella pneumoniae infections and on ceftazidime/avibactam resistance development | Gatti, Milo; Rinaldi, Matteo; Cojutti, Pier Giorgio; Bonazzetti, Cecilia; Siniscalchi, Antonio; T...onetti, Tommaso; Ambretti, Simone; Tedeschi, Sara; Giannella, Maddalena; Viale, Pierluigi; Pea, Federico | 2025-01-01 | ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | - | 1.01 Articolo in rivista | Gatti_AAC_2025.pdf; aac.00488-25-s0001.docx |
| A pre-post quasi-experimental study of the impact of TDM-guided aggressive pharmacokinetic/pharmacodynamic target attainment of continuous infusion ceftolozane/tazobactam monotherapy in treating severe Pseudomonas aeruginosa infections: A strategy useful for raising the bar? | Gatti, M.; Rinaldi, M.; Bonazzetti, C.; Siniscalchi, A.; Tonetti, T.; Ambretti, S.; Giannella, M....; Viale, P.; Pea, F. | 2025-01-01 | JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY | - | 1.01 Articolo in rivista | 1-s2.0-S1198743X25001247-main.pdf; dkaf098_supplementary_data.docx |
| Acute Respiratory Distress Syndrome and Fluid Management: Finding the Perfect Balance | Sbaraini Zernini, Irene; Nocera, Domenico; D'Albo, Rosanna; Tonetti, Tommaso | 2025-01-01 | JOURNAL OF CLINICAL MEDICINE | - | 1.01 Articolo in rivista | jcm-14-02067.pdf |
| Continuous positive airway pressure to prevent reintubation in patients recovering from cardiac surgery | Pasero, Daniela; Costamagna, Andrea; Filippini, Claudia; Blangetti, Ilaria; Cattaneo, Sergio; Bai...occhi, Massimo; Balata, Andrea; Bottiroli, Maurizio; Dambruoso, Pierpaolo; De Paulis, Stefano; Grazioli, Lorenzo; Locatelli, Alessandro; Lorini, Ferdinando Luca; Mascotti, Alessandra; Mondino, Michele Giovanni; Paparella, Domenico; Salvi, Luca; Tonetti, Tommaso; Tritapepe, Luigi; Ranieri, V. Marco | 2025-01-01 | EUROPEAN JOURNAL OF ANAESTHESIOLOGY | - | 1.01 Articolo in rivista | continuous_positive_airway_pressure_to_prevent.2.pdf |
| Generalized Periodic Discharges related to Anaesthesia Withdrawal (GRAWs) after status epilepticus in herpetic encephalitis: when less is more | Asioli, Gian Maria; Urbinati, Giacomo; Tonetti, Tommaso; Guarino, Maria | 2025-01-01 | NEUROLOGICAL SCIENCES | - | 1.01 Articolo in rivista | - |
| Keeping the horse with the cart: are we underdosing tazobactam even when using continuous-infusion ceftolozane/tazobactam for effectively preventing resistance development by ESBL-producing Enterobacterales? | Pai, Manjunath P.; Cojutti, Pier Giorgio; Gatti, Milo; Rinaldi, Matteo; Tonetti, Tommaso; Sinisca...lchi, Antonio; Viale, Pierluigi; Pea, Federico | 2025-01-01 | ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | - | 1.01 Articolo in rivista | aac.01215-25-s0001.docx; pai-et-al-2025-keeping-the-horse-with-the-cart-are-we-underdosing-tazobactam-even-when-using-continuous-infusion.pdf |
| Mechanical power and VILI: modeling limits and unknowns | Tonetti, T.; Marini, J. J. | 2025-01-01 | INTENSIVE CARE MEDICINE EXPERIMENTAL | - | 1.01 Articolo in rivista | s40635-024-00712-w.pdf |
| Personalizing beta-lactams therapy in critical patients undergoing RRT: moving a further step forward? | Tonetti, Tommaso; Gatti, Milo; Pea, Federico | 2025-01-01 | INTENSIVE CARE MEDICINE | - | 1.04 Replica / breve intervento (e simili) | - |
| Reply to Yang and to Xie and Wang | Mascia, L.; Tonetti, T. | 2025-01-01 | AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE | - | 1.04 Replica / breve intervento (e simili) | - |
| Targeting Pseudomonas aeruginosa resistance at the exposure frontier: a population PK/PD blueprint for ceftolozane/tazobactam continuous infusion | Cojutti, Pier Giorgio; Pai, Manjunath P.; Gatti, Milo; Rinaldi, Matteo; Tonetti, Tommaso; Sinisca...lchi, Antonio; Viale, Pierluigi; Pea, Federico | 2025-01-01 | ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | - | 1.01 Articolo in rivista | cojutti-et-al-2025-targeting-pseudomonas-aeruginosa-resistance-at-the-exposure-frontier-a-population-pk-pd-blueprint.pdf |
| TDM-Based Approach for Properly Managing Intravenous Isavuconazole Treatment in a Complex Case Mix of Critically Ill Patients | Gatti, Milo; Rinaldi, Matteo; De Paola, Riccardo; Siniscalchi, Antonio; Tonetti, Tommaso; Viale, ...Pierluigi; Pea, Federico | 2025-01-01 | ANTIBIOTICS | - | 1.01 Articolo in rivista | antibiotics-14-00777.pdf |
| The role of rapid and advanced microbiological methods in critical care: 2025 Emanuele Russo Delphi consensus | Sambri, Vittorio; Agnoletti, Vanni; Ambretti, Simone; Bartoletti, Michele; Bernaschi, Paola; Bign...ami, Elena Giovanna; Busani, Stefano; Campoli, Caterina; Carretto, Edoardo; Catena, Fausto; Coloretti, Irene; Cricca, Monica; De Pascale, Gennaro; De Rosa, Francesco Giuseppe; Fontana, Carla; Gherardi, Giovanni; Giannella, Maddalena; Girardis, Massimo; Mancini, Nicasio; Oliva, Alessandra; Podda, Mauro; Piazza, Ornella; Portunato, Federica; Poletti, Venerino; Viceconte, Giulio; Rocchetti, Andrea; Santonastaso, Domenico Pietro; Serapide, Francesca; Stefani, Stefania; Tascini, Carlo; Tebano, Gianpiero; Tosi, Martina; Tumbarello, Mario; Viaggi, Bruno; Viale, Pierluigi; Cristini, Francesco; Bassetti, Matteo; Falcone, Marco; Gentile, Ivan; Gobbi, Luca; Grasselli, Giacomo; Palamara, Anna Teresa; Rossolini, Gianmaria; Russo, Alessandro; Sanguinetti, Maurizio; Sartelli, Massimo; Tonetti, Tommaso | 2025-01-01 | CLINICAL MICROBIOLOGY AND INFECTION | - | 1.01 Articolo in rivista | 1-s2.0-S1198743X25004203-mmc1.docx; 3511666.pdf |
| Validation of a predictive risk score of aggressive PK/PD target non-attainment with continuous infusion piperacillin/tazobactam or meropenem in critically ill patients having documented Gram-negative infections | Gatti, Milo; Grimaldi, Pierantonio; Rinaldi, Matteo; Siniscalchi, Antonio; Tonetti, Tommaso; Vial...e, Pierluigi; Pea, Federico | 2025-01-01 | JOURNAL OF ANESTHESIA, ANALGESIA AND CRITICAL CARE | - | 1.01 Articolo in rivista | - |
| Association between respiratory distress time and invasive mechanical ventilation in COVID-19 patients: A multicentre regional cohort study | Busani, S; Coloretti, I; Baciarello, M; Bellini, V; Sarti, M; Biagioni, E; Tonelli, R; Marchioni,... A; Clini, E; Guaraldi, G; Mussini, C; Meschiari, M; Tonetti, T; Pisani, L; Nava, S; Bignami, E; Ranieri, M V; Girardis, M | 2024-01-01 | PULMONOLOGY | - | 1.01 Articolo in rivista | Association between respiratory distress time and invasive mechanical ventilation in COVID-19 patients A multicentre regional cohort study.pdf |
| Balancing the scales: achieving the optimal beta-lactam to beta-lactamase inhibitor ratio with continuous infusion piperacillin/tazobactam against extended spectrum beta-lactamase producing Enterobacterales | Cojutti, Pier Giorgio; Pai, Manjunath P.; Tonetti, Tommaso; Siniscalchi, Antonio; Viale, Pierluig...i; Pea, Federico | 2024-01-01 | ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | - | 1.01 Articolo in rivista | aac.01404-23.pdf; aac.01404-23-s0001.pdf |
| Comparative Impact of an Optimized PK/PD Target Attainment of Piperacillin-Tazobactam vs. Meropenem on the Trend over Time of SOFA Score and Inflammatory Biomarkers in Critically Ill Patients Receiving Continuous Infusion Monotherapy for Treating Documented Gram-Negative BSIs and/or VAP | Gatti, Milo; Rinaldi, Matteo; Tonetti, Tommaso; Siniscalchi, Antonio; Viale, Pierluigi; Pea, Fede...rico | 2024-01-01 | ANTIBIOTICS | - | 1.01 Articolo in rivista | antibiotics-13-00296.pdf |