ROMUALDI, PATRIZIA
 Distribuzione geografica
Continente #
NA - Nord America 5.948
EU - Europa 5.687
AS - Asia 5.065
AF - Africa 408
SA - Sud America 356
OC - Oceania 10
Continente sconosciuto - Info sul continente non disponibili 3
Totale 17.477
Nazione #
US - Stati Uniti d'America 5.877
IT - Italia 2.225
SG - Singapore 1.657
CN - Cina 1.626
GB - Regno Unito 1.059
VN - Vietnam 729
DE - Germania 513
SE - Svezia 420
HK - Hong Kong 406
IN - India 281
UA - Ucraina 280
BR - Brasile 254
RU - Federazione Russa 245
FR - Francia 242
CI - Costa d'Avorio 174
IE - Irlanda 173
NL - Olanda 154
KR - Corea 137
ZA - Sudafrica 84
TG - Togo 82
JP - Giappone 71
BG - Bulgaria 70
EE - Estonia 61
CH - Svizzera 47
FI - Finlandia 47
CA - Canada 40
SC - Seychelles 38
AR - Argentina 34
ID - Indonesia 32
JO - Giordania 26
BE - Belgio 23
GR - Grecia 23
AT - Austria 21
PL - Polonia 21
CL - Cile 18
BD - Bangladesh 17
EC - Ecuador 17
ES - Italia 16
TR - Turchia 14
MX - Messico 12
RO - Romania 12
PE - Perù 10
AU - Australia 9
IQ - Iraq 8
CZ - Repubblica Ceca 7
HN - Honduras 7
LY - Libia 7
PY - Paraguay 7
AE - Emirati Arabi Uniti 6
CO - Colombia 6
IL - Israele 6
PK - Pakistan 6
VE - Venezuela 6
AL - Albania 5
TH - Thailandia 5
TW - Taiwan 5
LB - Libano 4
MY - Malesia 4
SA - Arabia Saudita 4
SI - Slovenia 4
UZ - Uzbekistan 4
AZ - Azerbaigian 3
DK - Danimarca 3
DO - Repubblica Dominicana 3
GT - Guatemala 3
KE - Kenya 3
MA - Marocco 3
UY - Uruguay 3
A2 - ???statistics.table.value.countryCode.A2??? 2
BA - Bosnia-Erzegovina 2
DZ - Algeria 2
IR - Iran 2
KZ - Kazakistan 2
LT - Lituania 2
MU - Mauritius 2
NG - Nigeria 2
PH - Filippine 2
PR - Porto Rico 2
PT - Portogallo 2
SN - Senegal 2
TN - Tunisia 2
UG - Uganda 2
AM - Armenia 1
BF - Burkina Faso 1
BN - Brunei Darussalam 1
BW - Botswana 1
BY - Bielorussia 1
CG - Congo 1
CR - Costa Rica 1
EG - Egitto 1
EU - Europa 1
GD - Grenada 1
GE - Georgia 1
GY - Guiana 1
HR - Croazia 1
HU - Ungheria 1
JM - Giamaica 1
KH - Cambogia 1
LU - Lussemburgo 1
LV - Lettonia 1
Totale 17.465
Città #
Singapore 1.079
Southend 923
Ashburn 591
Fairfield 588
Santa Clara 459
Chandler 446
Hong Kong 400
Hefei 348
Dong Ket 295
Wilmington 293
Seattle 272
Bologna 253
Woodbridge 249
Princeton 239
Houston 228
Beijing 226
Cambridge 208
Milan 178
Ann Arbor 176
Abidjan 174
Dublin 168
Boardman 164
Jacksonville 160
Dallas 136
Seoul 131
Ho Chi Minh City 118
Rome 107
Turin 106
Westminster 98
Nanjing 97
Hanoi 95
Padova 95
Lomé 82
Berlin 77
Jinan 73
Los Angeles 72
Sofia 69
Tokyo 66
Buffalo 54
Saint Petersburg 49
Shenyang 49
Tappahannock 48
Redondo Beach 38
Guangzhou 36
Medford 34
San Diego 34
Changsha 33
Naples 33
New York 32
Mülheim 30
Bengaluru 28
Dearborn 28
Hebei 28
Shanghai 28
Tianjin 28
Ningbo 27
Amman 26
Frankfurt am Main 25
Zhengzhou 25
London 24
São Paulo 24
Florence 23
Brussels 22
Chicago 22
Helsinki 22
Hyderabad 22
Jakarta 22
Jiaxing 22
Redmond 22
Des Moines 21
Yubileyny 21
Nanchang 20
Nuremberg 20
Mahé 19
Norwalk 19
Falls Church 18
Haiphong 18
Forlì 17
Palermo 17
Phoenix 17
Toronto 17
Washington 17
Lappeenranta 16
Cagliari 15
Catania 15
Council Bluffs 15
Hangzhou 14
Taiyuan 14
Ferrara 13
Genoa 13
Haikou 13
Lanzhou 13
Orem 13
Redwood City 13
Verona 13
Wuhan 13
Bern 12
Modena 12
Munich 12
Brescia 11
Totale 10.958
Nome #
Farmacologia degli analgesici oppiacei 1.697
Prescribing opioids to patients with chronic pain: Translation of the Opioid Risk Tool into Italian 247
Effects of unburned tobacco smoke on inflammatory and oxidative mediators in the rat prefrontal cortex 213
On the toxicity of e-cigarettes consumption: Focus on pathological cellular mechanisms 206
Kainate Seizures Increase Nociceptin/Orphanin FQ Release in the Rat Hippocampus and Thalamus: a Microdialysis Study. 204
Chronic Trazodone and Citalopram Treatments Increase Trophic Factor and Circadian Rhythm Gene Expression in Rat Brain Regions Relevant for Antidepressant Efficacy 199
The active second-generation proteasome inhibitor oprozomib reverts the oxaliplatin-induced neuropathy symptoms 195
Acute and chronic cannabinoid extracts administration affects motor function in a CREAE model of multiple sclerosis 193
Differential time course of the effects of kappa-opioid agonist treatment on dynorphin A and on k-opioid receptor density 191
Activation of PPARγ Attenuates the Expression of Physical and Affective Nicotine Withdrawal Symptoms through Mechanisms Involving Amygdala and Hippocampus Neurotransmission 189
Role of serotonin on cocaine mediated effects on prodynorphin gene expression in the rat brain. 182
Supraspinal melatonin MT2 receptor agonism alleviates pain via a neural circuit that recruits mu opioid receptors 173
Early-life nicotine or cotinine exposure produces long-lasting sleep alterations and downregulation of hippocampal corticosteroid receptors in adult mice 170
Blockade of nociceptin/orphanin FQ transmission attenuates symptoms and neurodegenation associated with Parkinson's disease. 169
Cocaine and ethanol target 26S proteasome activity and gene expression in neuroblastoma cells 169
N/OFQ system in brain areas of nerve-injured mice: Its role in different aspects of neuropathic pain 168
Unburned Tobacco Smoke Affects Neuroinflammation-Related Pathways in the Rat Mesolimbic System. 165
Brain interstitial nociceptin/orphanin FQ levels are elevated in Parkinson's disease. 162
∆(9)-Tetrahydrocannabinol decreases NOP receptor density and mRNA levels in human SH-SY5Y cells. 158
Mystic Acetaldehyde: The Never-Ending Story on Alcoholism 157
Alterations in prodynorphin gene expression and dynorphin levels in different brain regions after chronic administration of 14-methoxy-metopon and oxycodone-6-oxime. 156
Kainic Acid Down-regulates NOP Receptor Density and Gene Expression in Human Neuroblastoma SH-SY5Y Cells. 155
Chronic and acute effects of 3,4-methylenedioxy-N-methylamphetamine ('Ecstasy') administration on the dynorphinergic system in the rat brain. 155
Treatment with the neurotoxic Aβ (25-35) peptide modulates the expression of neuroprotective factors Pin1, Sirtuin 1, and brain-derived neurotrophic factor in SH-SY5Y human neuroblastoma cells 155
Alterations of CREB and DARPP-32 phosphorylation following cocaine and monoaminergic uptake inhibitors. 153
Different alcohol exposures induce selective alterations on the expression of dynorphin and nociceptin systems related genes in rat brain. 152
The challenge of perioperative pain management in opioid-tolerant patients 151
Dynorphinergic system alterations in the corticostriatal circuitry of neuropathic mice support its role in the negative affective component of pain. 148
Targeting the JAK/STAT Pathway: A Combined Ligand- And Target-Based Approach 147
Peripheral leukocyte expression of the potential biomarker proteins Bdnf, Sirt1, and Psen1 is not regulated by promoter methylation in Alzheimer's disease patients 145
Nociceptive responses in melatonin MT2 receptor knockout mice compared to MT1 and double MT1/MT2 receptor knockout mice 145
Dynorphin/KOP and nociceptin/NOP gene expression and epigenetic changes by cocaine in rat striatum and nucleus accumbens 144
Alghedon Fentanyl Transdermal System 144
Current and Future Therapeutic Options in Pain Management: Multi-mechanistic Opioids Involving Both MOR and NOP Receptor Activation 142
Early social isolation differentially affects the glucocorticoid receptor system and alcohol-seeking behavior in male and female Marchigian Sardinian alcohol-preferring rats 141
Ethanol Induces Epigenetic Modulation of Prodynorphin and Pronociceptin Gene Expression in the Rat Amygdala Complex. 141
Morphine and Fentanyl Differently Affect MOP and NOP Gene Expression in Human Neuroblastoma SH-SY5Y Cells. 141
Proteasome subunit and opioid receptor gene expression down-regulation induced by paraquat and maneb in human neuroblastoma SH-SY5Y cells. 141
Combined exposure to agriculture pesticides, paraquat and maneb, induces alterations in the N/OFQ—NOPr and PDYN/KOPr systems in rats: Relevance to sporadic Parkinson's disease 138
Reply—Letter to the Editor: What to Do, and What Not to Do, When Diagnosing and Treating Breakthrough Cancer Pain (BTcP): Expert Opinion 138
Opioid gene expression changes and post-translational histone modifications at promoter regions in the rat nucleus accumbens after acute and repeated 3,4-methylenedioxy-methamphetamine (MDMA) exposure 137
Alterations of N/OFQ and NOP receptor gene expression in the substantia nigra and caudate putamen of MPP(+) and 6-OHDA lesioned rats. 136
What to Do, and What Not to Do, When Diagnosing and Treating Breakthrough Cancer Pain (BTcP): Expert Opinion 136
The k-opioid receptor agonist U-69593 prevents cocaine-induced DARPP-32 phosphorylation at Thr34 in the rat brain 135
Effects of prolonged treatment with the opiate tramadol on prodynorphin gene expression in rat CNS. 133
Alterations in prodynorphin gene expression in 6-OHDA lesioned rat brain. 133
Effects of acute ethanol exposure on class I HDACs family enzymes in wild-type and BDNF(+/-) mice 133
Chronic cocaine produces decreases in N/OFQ peptide levels in select rat brain regions. 132
Chronic delta(9)-tetrahydrocannabinol during adolescence provokes sex-dependent changes in the emotional profile in adult rats: behavioral and biochemical correlates. 132
Repeated nicotine exposure modulates prodynorphin and pronociceptin levels in the reward pathway 132
A new potent analgesic agent with reduced liability to produce morphine tolerance 131
EFFECTS OF 3,4-METHYLENDIOXY-N-METHYLAMPHETAMINE (MDMA, ‘ECSTASY’) ADMINISTRATION ON THE DYNORPHINERGIC SYSTEM IN THE RAT BRAIN. 130
The standardized Withania somnifera Dunal root extract alters basal and morphine-induced opioid receptor gene expression changes in neuroblastoma cells. 130
Modulation of the negative affective dimension of pain: Focus on selected neuropeptidergic system contributions 130
Nociceptin levels in the CSF of chronic pain patients with or without intrathecal administration of morphine. 129
Human apolipoprotein E4 modulates the expression of Pin1, Sirtuin 1, and Presenilin 1 in brain regions of targeted replacement apoE mice 128
NOP receptor antagonism reduces alcohol drinking in male and female rats through mechanisms involving the central amygdala and ventral tegmental area 128
Effects of Different Opioid Drugs on Oxidative Status and Proteasome Activity in SH-SY5Y Cells 126
Interplay between the endogenous opioid system and proteasome complex: Beyond signaling 126
Nociceptin/orphanin FQ prevents the antinociceptive action of paracetamol on the rat hot plate test. 125
Regulation of the genes encoding the ppN/OFQ and NOP receptor 125
An Exploratory Pilot Study of Changes in Global DNA Methylation in Patients Undergoing Major Breast Surgery Under Opioid-Based General Anesthesia 125
Opioid Receptor Gene Expression in Human Neuroblastoma SH-SY5Y Cells Following Tapentadol Exposure 124
Assessment and treatment of breakthrough cancer pain: From theory to clinical practice 124
Role of serotonin in the regulation of the dynorphinergic system by a kappa-opioid agonist and cocaine treatment in rat CNS. 123
Effects of the selective norepinephrine uptake inhibitor nisoxetine on prodynorphin gene expression in rat CNS 123
Dysregulation of nociceptin/orphanin fq and dynorphin systems in the extended amygdala of alcohol preferring marchigian sardinian (Msp) rats 123
Evidence of a PPARγ-mediated mechanism in the ability of Withania somnifera to attenuate tolerance to the antinociceptive effects of morphine 121
Selective DNA methylation of BDNF promoter in bipolar disorder: differences among patients with BDI and BDII. 120
Increased expression of CRF and CRF-receptors in dorsal striatum, hippocampus, and prefrontal cortex after the development of nicotine sensitization in rats 120
Modification of anxiety-like behaviors by nociceptin/orphanin FQ (N/OFQ) and time-dependent changes in N/OFQ-NOP gene expression following ethanol withdrawal. 119
Cocaine affects NOP receptor gene expression in SH-SY5Y cells 118
Prolonged nicotine exposure, via electronic cigarette, selectively increases Bdnf/TrkB transcription, dynorphin peptide levels and OLIG2 in male rat VTA 117
Sex-dependent effect of inflammatory pain on negative affective states is prevented by kappa opioid receptors blockade in the nucleus accumbens shell 117
Regulation of opioid gene expression in the rat brainstem by 3,4-methylenedioxymethamphetamine (MDMA): role of serotonin and involvement of CREB and ERK cascade. 117
Delta9-tetrahydrocannabinol down regulates NOP receptor gene expression in SH-SY5Y cells 115
Possibile role of NOCICEPTIN/OFQ-NOP system in experimental models of Parkinson disease, 115
Alcohol exposures induce selective alterations on endogenous opioid system genes regulation in rat amygdala: possible epigenetic mechanisms 115
Alterations of the dynorphinergic system during tolerance development in rat brain by novel opioid compounds 115
Communal nesting differentially attenuates the impact of pre-weaning social isolation on behavior in male and female rats during adolescence and adulthood 114
Modulation of nociceptin/NOP system by delta9-THC in SH-SY5Y cell line 111
Interplay between prokineticins and histone demethylase kdm6a in a murine model of bortezomib-induced neuropathy 111
Regulation of NOP receptor density by delta-9-tetrahydrocannabinol treatment in SH-SY5Y cells. 110
Transcriptional and epigenetic phenomena in peripheral blood cells of monozygotic twins discordant for alzheimer's disease, a case report 110
Selection of nutraceutical compounds as COX inhibitors by molecular topology 110
ROLE OF DIFFERENT NEUROTRANSMITTERS ON COCAINE-MEDIATED EFFECTS ON PRODYNORPHIN GENE EXPRESSION AND CREB ACTIVATION IN THE RAT BRAIN. 109
Il Sistema Oppioide 108
XI CONVEGNO MONOTEMATICO Società Italiana di Farmacologia "NEUROFARMACOLOGIA E NEUROBIOLOGIA DELLE DIPENDENZE" Bologna, Complesso di S. Giovanni in Monte, 9 settembre 2005 107
Epigenetic mechanisms of rapid-acting antidepressants. 105
The prolonged buprenorphine administration reduces the NOP receptor density in rat cerebral areas 105
Different impact of chronic tramadol or morphine on prodynorphin gene expression 105
Safe use of opioids in chronic kidney disease and hemodialysis patients: Tips and tricks for non-pain specialists 105
Outcomes of early social experiences on glucocorticoid and endocannabinoid systems in the prefrontal cortex of male and female adolescent rats 104
The effects of nonsteroidal anti-inflammatory drugs on clinical outcomes, synovial fluid cytokine concentration and signal transduction pathways in knee osteoarthritis. A randomized open label trial 104
Pharmacology of opiate analgesics for chronic pain management - La gestione del dolore cronico: Farmacologia degli analgesici oppiacei 103
Cross-talk between CB1 and NOP receptors in human neuroblastoma SH-SY5Y cells 103
INVOLVEMENT OF SEROTONIN IN DYNORPHINERGIC SYSTEM REGULATION BY KAPPA-OPIOID AGONIST AND COCAINE TREATMENTS 103
Investigation on DNA methylation status of opioid peptides promoters in PBMCs of subjects with bipolar disorder 102
A role for epigenetic mechanisms in the regulation of prodynorphin expression by alcohol 102
Effects of the selective neurotensin antagonist SR 142948A on 3,4-methylenedioxymethamphetamine-induced behaviours in mice. 102
Totale 15.270
Categoria #
all - tutte 50.200
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 50.200


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20211.020 0 0 0 0 0 47 57 98 139 107 125 447
2021/20221.827 177 84 133 95 182 124 86 169 77 55 302 343
2022/20232.233 241 308 91 260 139 195 86 123 435 60 210 85
2023/20241.008 64 125 68 95 66 132 50 73 63 92 90 90
2024/20253.837 229 494 315 283 675 193 350 131 100 202 203 662
2025/20263.685 506 761 764 523 816 315 0 0 0 0 0 0
Totale 17.913