ROMUALDI, PATRIZIA
 Distribuzione geografica
Continente #
AS - Asia 6.757
NA - Nord America 6.751
EU - Europa 6.162
AF - Africa 448
SA - Sud America 415
OC - Oceania 11
Continente sconosciuto - Info sul continente non disponibili 3
Totale 20.547
Nazione #
US - Stati Uniti d'America 6.662
IT - Italia 2.356
SG - Singapore 1.928
CN - Cina 1.869
VN - Vietnam 1.573
GB - Regno Unito 1.077
DE - Germania 540
HK - Hong Kong 450
SE - Svezia 420
FR - Francia 396
IN - India 319
BR - Brasile 292
UA - Ucraina 284
RU - Federazione Russa 249
IE - Irlanda 179
CI - Costa d'Avorio 174
NL - Olanda 169
KR - Corea 156
FI - Finlandia 117
JP - Giappone 116
ZA - Sudafrica 96
TG - Togo 83
BG - Bulgaria 70
EE - Estonia 62
CH - Svizzera 56
CA - Canada 51
AR - Argentina 41
BD - Bangladesh 40
SC - Seychelles 38
ID - Indonesia 36
PH - Filippine 36
IQ - Iraq 34
JO - Giordania 33
TH - Thailandia 32
ES - Italia 30
GR - Grecia 27
PL - Polonia 26
BE - Belgio 23
TR - Turchia 23
CL - Cile 22
AT - Austria 21
TW - Taiwan 21
EC - Ecuador 19
MX - Messico 17
PK - Pakistan 16
RO - Romania 13
SA - Arabia Saudita 12
PE - Perù 11
AU - Australia 10
VE - Venezuela 10
KE - Kenya 9
HN - Honduras 8
UZ - Uzbekistan 8
AE - Emirati Arabi Uniti 7
AL - Albania 7
CO - Colombia 7
CZ - Repubblica Ceca 7
IL - Israele 7
LY - Libia 7
MY - Malesia 7
PY - Paraguay 7
DZ - Algeria 6
MA - Marocco 6
AZ - Azerbaigian 5
DK - Danimarca 5
UY - Uruguay 5
EG - Egitto 4
GT - Guatemala 4
LB - Libano 4
LT - Lituania 4
OM - Oman 4
SI - Slovenia 4
TN - Tunisia 4
DO - Repubblica Dominicana 3
ET - Etiopia 3
GH - Ghana 3
HU - Ungheria 3
IR - Iran 3
MD - Moldavia 3
PT - Portogallo 3
SN - Senegal 3
A2 - ???statistics.table.value.countryCode.A2??? 2
BA - Bosnia-Erzegovina 2
GE - Georgia 2
KH - Cambogia 2
KZ - Kazakistan 2
MN - Mongolia 2
MU - Mauritius 2
NG - Nigeria 2
PR - Porto Rico 2
TJ - Tagikistan 2
UG - Uganda 2
AM - Armenia 1
BF - Burkina Faso 1
BH - Bahrain 1
BN - Brunei Darussalam 1
BW - Botswana 1
BY - Bielorussia 1
CG - Congo 1
CR - Costa Rica 1
Totale 20.525
Città #
Singapore 1.302
Southend 923
Ashburn 635
Fairfield 588
San Jose 522
Santa Clara 467
Chandler 446
Hong Kong 423
Hefei 350
Ho Chi Minh City 324
Dong Ket 295
Wilmington 293
Hanoi 289
Bologna 280
Seattle 272
Woodbridge 249
Princeton 239
Beijing 229
Houston 229
Cambridge 208
Milan 190
Ann Arbor 176
Abidjan 174
Dublin 174
Boardman 165
Jacksonville 160
Dallas 142
Lauterbourg 135
Seoul 133
Rome 108
Turin 107
Tokyo 102
Nanjing 98
Westminster 98
Padova 95
Helsinki 89
Lomé 83
Berlin 78
Los Angeles 75
Jinan 73
Council Bluffs 72
Sofia 69
Buffalo 54
Shenyang 50
Saint Petersburg 49
Haiphong 48
New York 48
Tappahannock 48
Frankfurt am Main 45
Guangzhou 45
Shanghai 41
Da Nang 38
Redondo Beach 38
Changsha 36
Naples 35
San Diego 35
Medford 34
Amman 33
Tianjin 31
Mülheim 30
São Paulo 30
Bengaluru 28
Dearborn 28
Hebei 28
Ningbo 28
London 26
Zhengzhou 26
Chicago 25
Florence 24
Hyderabad 24
Nuremberg 23
Brussels 22
Des Moines 22
Jakarta 22
Jiaxing 22
Orem 22
Redmond 22
Yubileyny 21
Bangkok 20
Nanchang 20
Hangzhou 19
Mahé 19
Norwalk 19
Phoenix 19
Falls Church 18
Genoa 18
Lappeenranta 18
Palermo 18
Paris 18
Forlì 17
Johannesburg 17
Toronto 17
Washington 17
Wuhan 16
Cagliari 15
Catania 15
Hải Dương 15
Amsterdam 14
Biên Hòa 14
Taiyuan 14
Totale 12.717
Nome #
Farmacologia degli analgesici oppiacei 1.780
Prescribing opioids to patients with chronic pain: Translation of the Opioid Risk Tool into Italian 278
Chronic Trazodone and Citalopram Treatments Increase Trophic Factor and Circadian Rhythm Gene Expression in Rat Brain Regions Relevant for Antidepressant Efficacy 260
On the toxicity of e-cigarettes consumption: Focus on pathological cellular mechanisms 257
Effects of unburned tobacco smoke on inflammatory and oxidative mediators in the rat prefrontal cortex 240
The active second-generation proteasome inhibitor oprozomib reverts the oxaliplatin-induced neuropathy symptoms 232
Prolonged nicotine exposure, via electronic cigarette, selectively increases Bdnf/TrkB transcription, dynorphin peptide levels and OLIG2 in male rat VTA 230
Supraspinal melatonin MT2 receptor agonism alleviates pain via a neural circuit that recruits mu opioid receptors 220
Activation of PPARγ Attenuates the Expression of Physical and Affective Nicotine Withdrawal Symptoms through Mechanisms Involving Amygdala and Hippocampus Neurotransmission 220
Kainate Seizures Increase Nociceptin/Orphanin FQ Release in the Rat Hippocampus and Thalamus: a Microdialysis Study. 216
Acute and chronic cannabinoid extracts administration affects motor function in a CREAE model of multiple sclerosis 215
Treatment with the neurotoxic Aβ (25-35) peptide modulates the expression of neuroprotective factors Pin1, Sirtuin 1, and brain-derived neurotrophic factor in SH-SY5Y human neuroblastoma cells 204
Early-life nicotine or cotinine exposure produces long-lasting sleep alterations and downregulation of hippocampal corticosteroid receptors in adult mice 201
Differential time course of the effects of kappa-opioid agonist treatment on dynorphin A and on k-opioid receptor density 200
Role of serotonin on cocaine mediated effects on prodynorphin gene expression in the rat brain. 196
N/OFQ system in brain areas of nerve-injured mice: Its role in different aspects of neuropathic pain 191
∆(9)-Tetrahydrocannabinol decreases NOP receptor density and mRNA levels in human SH-SY5Y cells. 190
Unburned Tobacco Smoke Affects Neuroinflammation-Related Pathways in the Rat Mesolimbic System. 189
Cocaine and ethanol target 26S proteasome activity and gene expression in neuroblastoma cells 186
Nociceptive responses in melatonin MT2 receptor knockout mice compared to MT1 and double MT1/MT2 receptor knockout mice 185
Blockade of nociceptin/orphanin FQ transmission attenuates symptoms and neurodegenation associated with Parkinson's disease. 182
Mystic Acetaldehyde: The Never-Ending Story on Alcoholism 179
Alterations in prodynorphin gene expression and dynorphin levels in different brain regions after chronic administration of 14-methoxy-metopon and oxycodone-6-oxime. 177
The challenge of perioperative pain management in opioid-tolerant patients 177
Brain interstitial nociceptin/orphanin FQ levels are elevated in Parkinson's disease. 175
Different alcohol exposures induce selective alterations on the expression of dynorphin and nociceptin systems related genes in rat brain. 175
Targeting the JAK/STAT Pathway: A Combined Ligand- And Target-Based Approach 173
Current and Future Therapeutic Options in Pain Management: Multi-mechanistic Opioids Involving Both MOR and NOP Receptor Activation 171
Early social isolation differentially affects the glucocorticoid receptor system and alcohol-seeking behavior in male and female Marchigian Sardinian alcohol-preferring rats 167
Dynorphinergic system alterations in the corticostriatal circuitry of neuropathic mice support its role in the negative affective component of pain. 167
Kainic Acid Down-regulates NOP Receptor Density and Gene Expression in Human Neuroblastoma SH-SY5Y Cells. 166
Peripheral leukocyte expression of the potential biomarker proteins Bdnf, Sirt1, and Psen1 is not regulated by promoter methylation in Alzheimer's disease patients 166
Alghedon Fentanyl Transdermal System 166
Chronic and acute effects of 3,4-methylenedioxy-N-methylamphetamine ('Ecstasy') administration on the dynorphinergic system in the rat brain. 165
An Exploratory Pilot Study of Changes in Global DNA Methylation in Patients Undergoing Major Breast Surgery Under Opioid-Based General Anesthesia 164
Proteasome subunit and opioid receptor gene expression down-regulation induced by paraquat and maneb in human neuroblastoma SH-SY5Y cells. 163
Alterations of CREB and DARPP-32 phosphorylation following cocaine and monoaminergic uptake inhibitors. 162
Modulation of the negative affective dimension of pain: Focus on selected neuropeptidergic system contributions 162
Morphine and Fentanyl Differently Affect MOP and NOP Gene Expression in Human Neuroblastoma SH-SY5Y Cells. 161
Repeated nicotine exposure modulates prodynorphin and pronociceptin levels in the reward pathway 161
Combined exposure to agriculture pesticides, paraquat and maneb, induces alterations in the N/OFQ—NOPr and PDYN/KOPr systems in rats: Relevance to sporadic Parkinson's disease 158
Effects of Different Opioid Drugs on Oxidative Status and Proteasome Activity in SH-SY5Y Cells 157
NOP receptor antagonism reduces alcohol drinking in male and female rats through mechanisms involving the central amygdala and ventral tegmental area 157
Dynorphin/KOP and nociceptin/NOP gene expression and epigenetic changes by cocaine in rat striatum and nucleus accumbens 156
Effects of prolonged treatment with the opiate tramadol on prodynorphin gene expression in rat CNS. 155
Ethanol Induces Epigenetic Modulation of Prodynorphin and Pronociceptin Gene Expression in the Rat Amygdala Complex. 155
Opioid gene expression changes and post-translational histone modifications at promoter regions in the rat nucleus accumbens after acute and repeated 3,4-methylenedioxy-methamphetamine (MDMA) exposure 155
The standardized Withania somnifera Dunal root extract alters basal and morphine-induced opioid receptor gene expression changes in neuroblastoma cells. 155
EFFECTS OF 3,4-METHYLENDIOXY-N-METHYLAMPHETAMINE (MDMA, ‘ECSTASY’) ADMINISTRATION ON THE DYNORPHINERGIC SYSTEM IN THE RAT BRAIN. 154
Interplay between the endogenous opioid system and proteasome complex: Beyond signaling 153
Human apolipoprotein E4 modulates the expression of Pin1, Sirtuin 1, and Presenilin 1 in brain regions of targeted replacement apoE mice 151
What to Do, and What Not to Do, When Diagnosing and Treating Breakthrough Cancer Pain (BTcP): Expert Opinion 151
Reply—Letter to the Editor: What to Do, and What Not to Do, When Diagnosing and Treating Breakthrough Cancer Pain (BTcP): Expert Opinion 151
Effects of acute ethanol exposure on class I HDACs family enzymes in wild-type and BDNF(+/-) mice 151
Alterations in prodynorphin gene expression in 6-OHDA lesioned rat brain. 150
Alterations of N/OFQ and NOP receptor gene expression in the substantia nigra and caudate putamen of MPP(+) and 6-OHDA lesioned rats. 149
The k-opioid receptor agonist U-69593 prevents cocaine-induced DARPP-32 phosphorylation at Thr34 in the rat brain 148
Dysregulation of nociceptin/orphanin fq and dynorphin systems in the extended amygdala of alcohol preferring marchigian sardinian (Msp) rats 148
Regulation of the genes encoding the ppN/OFQ and NOP receptor 147
Opioid Receptor Gene Expression in Human Neuroblastoma SH-SY5Y Cells Following Tapentadol Exposure 145
A new potent analgesic agent with reduced liability to produce morphine tolerance 145
Increased expression of CRF and CRF-receptors in dorsal striatum, hippocampus, and prefrontal cortex after the development of nicotine sensitization in rats 145
Sex-dependent effect of inflammatory pain on negative affective states is prevented by kappa opioid receptors blockade in the nucleus accumbens shell 144
Chronic delta(9)-tetrahydrocannabinol during adolescence provokes sex-dependent changes in the emotional profile in adult rats: behavioral and biochemical correlates. 144
Chronic cocaine produces decreases in N/OFQ peptide levels in select rat brain regions. 143
Nociceptin levels in the CSF of chronic pain patients with or without intrathecal administration of morphine. 141
Evidence of a PPARγ-mediated mechanism in the ability of Withania somnifera to attenuate tolerance to the antinociceptive effects of morphine 141
Selective DNA methylation of BDNF promoter in bipolar disorder: differences among patients with BDI and BDII. 140
Communal nesting differentially attenuates the impact of pre-weaning social isolation on behavior in male and female rats during adolescence and adulthood 137
Modification of anxiety-like behaviors by nociceptin/orphanin FQ (N/OFQ) and time-dependent changes in N/OFQ-NOP gene expression following ethanol withdrawal. 137
Alcohol exposures induce selective alterations on endogenous opioid system genes regulation in rat amygdala: possible epigenetic mechanisms 136
Assessment and treatment of breakthrough cancer pain: From theory to clinical practice 136
Cocaine affects NOP receptor gene expression in SH-SY5Y cells 135
Regulation of opioid gene expression in the rat brainstem by 3,4-methylenedioxymethamphetamine (MDMA): role of serotonin and involvement of CREB and ERK cascade. 135
Nociceptin/orphanin FQ prevents the antinociceptive action of paracetamol on the rat hot plate test. 135
Interplay between prokineticins and histone demethylase kdm6a in a murine model of bortezomib-induced neuropathy 135
Role of serotonin in the regulation of the dynorphinergic system by a kappa-opioid agonist and cocaine treatment in rat CNS. 134
Effects of the selective norepinephrine uptake inhibitor nisoxetine on prodynorphin gene expression in rat CNS 134
Possibile role of NOCICEPTIN/OFQ-NOP system in experimental models of Parkinson disease, 132
Activation of Antioxidant and Proteolytic Pathways in the Nigrostriatal Dopaminergic System After 3,4-Methylenedioxymethamphetamine Administration: Sex-Related Differences 132
Tapentadol: An analgesic that differs from classic opioids due to its noradrenergic mechanism of action 130
Outcomes of early social experiences on glucocorticoid and endocannabinoid systems in the prefrontal cortex of male and female adolescent rats 129
Delta9-tetrahydrocannabinol down regulates NOP receptor gene expression in SH-SY5Y cells 127
Il Sistema Oppioide 127
Alterations of the dynorphinergic system during tolerance development in rat brain by novel opioid compounds 127
Safe use of opioids in chronic kidney disease and hemodialysis patients: Tips and tricks for non-pain specialists 127
Regulation of NOP receptor density by delta-9-tetrahydrocannabinol treatment in SH-SY5Y cells. 126
Pharmacology of opiate analgesics for chronic pain management - La gestione del dolore cronico: Farmacologia degli analgesici oppiacei 126
ROLE OF DIFFERENT NEUROTRANSMITTERS ON COCAINE-MEDIATED EFFECTS ON PRODYNORPHIN GENE EXPRESSION AND CREB ACTIVATION IN THE RAT BRAIN. 125
Nociceptive behavior and central neuropeptidergic dysregulations in male and female mice of a Fabry disease animal model 125
Modulation of nociceptin/NOP system by delta9-THC in SH-SY5Y cell line 123
Investigation on DNA methylation status of opioid peptides promoters in PBMCs of subjects with bipolar disorder 123
Epigenetic mechanisms of rapid-acting antidepressants. 122
XI CONVEGNO MONOTEMATICO Società Italiana di Farmacologia "NEUROFARMACOLOGIA E NEUROBIOLOGIA DELLE DIPENDENZE" Bologna, Complesso di S. Giovanni in Monte, 9 settembre 2005 121
A role for epigenetic mechanisms in the regulation of prodynorphin expression by alcohol 120
Different impact of chronic tramadol or morphine on prodynorphin gene expression 119
INVOLVEMENT OF SEROTONIN IN DYNORPHINERGIC SYSTEM REGULATION BY KAPPA-OPIOID AGONIST AND COCAINE TREATMENTS 119
Selection of nutraceutical compounds as COX inhibitors by molecular topology 119
Short-term withdrawal from repeated exposure to cocaine during adolescence modulates dynorphin mRNA levels and BDNF signaling in the rat nucleus accumbens 119
The effects of nonsteroidal anti-inflammatory drugs on clinical outcomes, synovial fluid cytokine concentration and signal transduction pathways in knee osteoarthritis. A randomized open label trial 118
Totale 17.548
Categoria #
all - tutte 55.223
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 55.223


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021679 0 0 0 0 0 0 0 0 0 107 125 447
2021/20221.827 177 84 133 95 182 124 86 169 77 55 302 343
2022/20232.233 241 308 91 260 139 195 86 123 435 60 210 85
2023/20241.008 64 125 68 95 66 132 50 73 63 92 90 90
2024/20253.837 229 494 315 283 675 193 350 131 100 202 203 662
2025/20266.814 506 761 764 523 816 418 795 508 1.274 449 0 0
Totale 21.042