CRIS Current Research Information System

DI STEFANO, GIUSEPPINA
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
NA - Nord America 3.090
EU - Europa 2.166
AS - Asia 1.111
AF - Africa 178
OC - Oceania 6
SA - Sud America 2
Continente sconosciuto - Info sul continente non disponibili 1
Totale 6.554
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 3.078
IT - Italia 537
GB - Regno Unito 513
CN - Cina 381
SG - Singapore 327
SE - Svezia 220
DE - Germania 204
VN - Vietnam 171
IN - India 139
UA - Ucraina 137
CH - Svizzera 124
IE - Irlanda 115
TG - Togo 85
FR - Francia 80
RU - Federazione Russa 59
BG - Bulgaria 42
EE - Estonia 36
ZA - Sudafrica 32
NG - Nigeria 24
CI - Costa d'Avorio 23
JO - Giordania 22
BE - Belgio 19
HK - Hong Kong 15
NL - Olanda 15
FI - Finlandia 13
SC - Seychelles 13
ES - Italia 12
TW - Taiwan 11
ID - Indonesia 10
KR - Corea 10
CA - Canada 9
HR - Croazia 9
JP - Giappone 9
AT - Austria 8
GR - Grecia 7
AU - Australia 5
TR - Turchia 5
PL - Polonia 3
PT - Portogallo 3
RO - Romania 3
AE - Emirati Arabi Uniti 2
BR - Brasile 2
CZ - Repubblica Ceca 2
DK - Danimarca 2
IQ - Iraq 2
IR - Iran 2
LB - Libano 2
MD - Moldavia 2
MX - Messico 2
A2 - ???statistics.table.value.countryCode.A2??? 1
MU - Mauritius 1
MY - Malesia 1
NZ - Nuova Zelanda 1
PH - Filippine 1
PR - Porto Rico 1
RS - Serbia 1
SA - Arabia Saudita 1
Totale 6.554
Salva come PNG Salva come JPEG
Città #
Southend 442
Fairfield 374
Chandler 323
Singapore 297
Ashburn 274
Bologna 205
Woodbridge 202
Santa Clara 194
Wilmington 169
Houston 160
Seattle 159
Ann Arbor 122
Bern 116
Dublin 113
Cambridge 100
Princeton 100
Dong Ket 94
Jacksonville 86
Lomé 85
Boardman 75
New York 56
Redmond 46
Sofia 42
Westminster 41
Padova 39
Nanjing 36
Berlin 31
Shenyang 28
Milan 26
Turin 25
Abeokuta 24
Abidjan 23
Jinan 23
Amman 22
Beijing 22
San Diego 22
Saint Petersburg 19
Brussels 16
Genoa 16
Mülheim 15
Changsha 14
Nanchang 14
Falls Church 13
Mahé 13
Redwood City 13
Wanchai 13
Hangzhou 12
Los Angeles 12
Shanghai 12
Tianjin 12
Cesenatico 11
Hebei 11
Helsinki 11
Amsterdam 10
Jakarta 10
Zhengzhou 10
Bremen 9
Des Moines 9
Guangzhou 8
Haikou 8
Jiaxing 8
Nerviano 8
Bengaluru 7
Dearborn 7
Exeter 7
Hyderabad 7
Paris 7
Taiyuan 7
Carlsbad 6
Cento 6
Fano 6
Montescudo 6
Olalla 6
Rome 6
Taizhou 6
Vienna 6
Istanbul 5
Kunming 5
Medford 5
Sant'agata De' Goti 5
Tokyo 5
Verona 5
Bühl 4
Chandigarh 4
Chantilly 4
Frankfurt am Main 4
Genova 4
London 4
Lucca 4
Modena 4
Munich 4
New Taipei City 4
Nice 4
Nuremberg 4
Phoenix 4
Qingdao 4
Québec 4
Rijeka 4
San Venanzo 4
Zurich 4
Totale 4.695
Salva come PNG Salva come JPEG
Nome #
A RAD51/BRCA2 small molecule inhibitor enhances the antineoplastic effect of the PARPi talazoparib in pancreatic cancer 194
Rad51/Brca2 Disruptors Inhibit Homologous Recombination and Synergize with Olaparib in Pancreatic Cancer Cells 185
Synthetic Lethality in Pancreatic Cancer: Discovery of a New RAD51-BRCA2 Small Molecule Disruptor That Inhibits Homologous Recombination and Synergizes with Olaparib 182
A novel method for coupling doxorubicin to lactosaminated human albumin by an acid sensitive hydrazone bond: synthesis, characterization and preliminary biological properties of the conjugate. 180
Characterisation of the conjugate of the (6-maleimidocaproyl)hydrazone derivative of doxorubicin with lactosaminated human albumin by 13C NMR spectroscopy. 178
Altered glycosylation profile of purified plasma ACT from Alzheimer's disease. 174
Inhibition of lactic dehydrogenase as a way to increase the anti-proliferative effect of multi-targeted kinase inhibitors. 162
The activation of lactate dehydrogenase induced by mTOR drives neoplastic change in breast epithelial cells 161
Liver targeted doxorubicin: effects on rat regenerating hepatocytes. 156
Impairment of aerobic glycolysis by inhibitors of lactic dehydrogenase hinders the growth of human hepatocellular carcinoma cell lines. 155
Binding of the doxorubicin-lactosaminated human albumin conjugate to HCC cells is mediated by the drug moieties. 145
LDH inhibition impacts on heat shock response and induces senescence of hepatocellular carcinoma cells 145
Galloflavin, a new lactate dehydrogenase inhibitor, induces the death of human breast cancer cells with different glycolytic attitude by affecting distinct signaling pathways. 143
Lactate dehydrogenase inhibitors can reverse inflammation induced changes in colon cancer cells 142
Efficacy of doxorubicin coupled to lactosaminated albumin on rat hepatocellular carcinomas evaluated by ultrasound imaging. 137
Enhanced uptake of lactosaminated human albumin by rat hepatocarcinomas: implications for an improved chemotherapy of primary liver tumors. 136
Uso di coniugati della doxorubicina con albumina lattosaminata 136
Coupling of lactose molecules to the carrier protein hinders the spleen and bone marrow uptake of doxorubicin conjugated with human albumin 136
Galloflavin (CAS 568-80-9), a novel inhibitor of lactate dehydrogenase. 136
A conjugate of doxorubicin with lactosaminated albumin enhances the drug concentrations in all the forms of rat hepatocellular carcinomas independently of their differentation grade. 134
Doxorubicin coupled to lactosaminated human albumin: a hepatocellular carcinoma targeted drug. 133
Lactate dehydrogenase inhibitors sensitize lymphoma cells to cisplatin without enhancing the drug effects on immortalized normal lymphocytes. 130
Doxorubicin coupled to lactosaminated albumin: effect of heterogeneity in drug load on conjugate disposition and hepatocellular carcinoma uptake in rats. 129
Effect of sorafenib on the energy metabolism of hepatocellular carcinoma cells. 128
Synthetic Lethality Triggered by Combining Olaparib with BRCA2-Rad51 Disruptors 128
Doxorubicin coupled to lactosaminated albumin: effects on rats with liver fibrosis and cirrhosis. 127
Synthesis of natural urolithin M6, a galloflavin mimetic, as a potential inhibitor of lactate dehydrogenase A 122
Doxorubicin coupled to lactosaminated albumin inhibits the growth of hepatocellular carcinomas induced in rats by diethylnitrosamine. 122
Galloflavin prevents the binding of lactate dehydrogenase A to single stranded DNA and inhibits RNA synthesis in cultured cells. 119
Albumin-drug conjugates in the treatment of hepatic disorders. 118
Lactate dehydrogenase inhibition affects homologous recombination repair independently of cell metabolic asset; implications for anticancer treatment 118
The enhancement of interstitial transport of a doxorubicin-lactosaminated albumin conjugate by imatinib: in rat hepatocellular carcinoma it is not preferentially higher than that in liver and bone marrow. 114
Metabolic activation triggered by cAMP in MCF-7 cells generates lethal vulnerability to combined oxamate/etomoxir 114
Elevated plasma levels of alpha-1-antichymotripsin in age-related cognitive decline and Alzheimer's disease; a poential therapeutci target. 108
Procedura per la preparazione di coniugati della doxorubicina con l’albumina umana lattosaminata 107
Doxorubicin coupled to lactosaminated albumin: enhanced drug levels in rat hepatocarcinomas. 103
Galloflavin suppresses lactate dehydrogenase activity and causes MYC downregulationin Burkitt lymphoma cells via NAD/NADH-dependent inhibition of sirtuin-1 101
null 101
Process for the preparation of doxorubicin conjugates with lactosaminated human albumin 99
Insights into the activity of ARN24089, a new RAD51-BRCA2 disruptor that inhibits homologous recombination and achieves synthetic lethality in pancreatic cancer 98
Use of conjugates of doxorubicin with lactosaminated albumin. 93
Lactosaminated human albumin: a hepatotropic carrier of drugs. 88
NAD metabolism and functions: a common therapeutic target for neoplastic, metabolic and neurodegenerative diseases 81
null 78
Lactate is a potential promoter of tamoxifen resistance in MCF7 cells 74
Lactate Upregulates the Expression of DNA Repair Genes, Causing Intrinsic Resistance of Cancer Cells to Cisplatin 72
null 71
Identification and subsequent development of RAD51-BRCA2 disruptors through a fragment-based approach 66
Identification of N-acylhydrazone derivatives as novel lactate dehydrogenase A inhibitors 62
Allosteric transitions of rabbit skeletal muscle lactate dehydrogenase induced by pH-dependent dissociation of the tetrameric enzyme 60
The Mechanistic Understanding of RAD51 Defibrillation: A Critical Step in BRCA2-Mediated DNA Repair by Homologous Recombination 53
null 51
Lactate dehydrogenase inhibition: Exploring possible applications beyond cancer treatment 48
An 19F NMR fragment-based approach for the discovery and development of BRCA2-RAD51 inhibitors to pursuit synthetic lethality in combination with PARP inhibition in pancreatic cancer 46
Inhibition of lactate dehydrogenase activity as an approach to cancer therapy 45
Human lactate dehydrogenase A undergoes allosteric transitions under pH conditions inducing the dissociation of the tetrameric enzyme 41
Lactate Can Modulate the Antineoplastic Effects of Doxorubicin and Relieve the Drug's Oxidative Damage on Cardiomyocytes 37
Lactate preserves genome integrity and extends proliferative potential in cancer cells 36
Expression of UDP-GalNAc:NeuAc alpha 2,3Gal beta-R beta 1,4(GalNAc to Gal) N-acetylgalactosaminyltransferase involved in the synthesis of Sda antigen in human large intestine and colorectal carcinomas 30
Preomic profile of BxPC-3 cells after treatment with BRC4 27
Increased CMP-NeuAc:Gal beta 1,4GlcNAc-R alpha 2,6 sialyltransferase activity in human colorectal cancer tissues 27
RAD51 nuclear recruitment and inhibition towards innovative strategies against pancreatic cancer 21
Peptides inhibiting the assembly of monomeric human l‐lactate dehydrogenase into catalytically active homotetramer decrease the synthesis of lactate in cultured cells 19
Postnatal development of rat colon epithelial cells is associated with changes in the expression of the beta 1,4-N-acetylgalactosaminyltransferase involved in the synthesis of Sda antigen of alpha 2,6-sialyltransferase activity towards N-acetyl-lactosamine 16
Proteomic profile of BxPC-3 cells after treatment with BRC4 16
Lactate-Induced HBEGF Shedding and EGFR Activation: Paving the Way to a New Anticancer Therapeutic Opportunity 15
Totale 6.709
Salva come PNG Salva come JPEG
Categoria #
all - tutte 17.023
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 17.023
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201.132 0 0 0 0 155 150 179 222 193 90 64 79
2020/2021834 153 44 31 40 60 80 21 32 106 50 42 175
2021/2022986 110 19 76 84 74 45 42 73 39 66 190 168
2022/20231.365 111 219 50 154 115 89 40 51 207 38 71 220
2023/2024670 89 79 46 57 41 121 66 37 15 41 22 56
2024/2025888 108 167 119 159 335 0 0 0 0 0 0 0
Totale 6.709