CRIS Current Research Information System

CIANI, ELISABETTA
 Distribuzione geografica
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Continente #
NA - Nord America 4.997
EU - Europa 3.932
AS - Asia 3.826
AF - Africa 470
SA - Sud America 187
OC - Oceania 4
Totale 13.416
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Nazione #
US - Stati Uniti d'America 4.950
IT - Italia 1.426
CN - Cina 1.159
SG - Singapore 1.159
VN - Vietnam 692
GB - Regno Unito 675
DE - Germania 471
HK - Hong Kong 307
SE - Svezia 285
NL - Olanda 195
IN - India 187
IE - Irlanda 144
RU - Federazione Russa 137
SC - Seychelles 135
FR - Francia 134
TG - Togo 134
BR - Brasile 131
UA - Ucraina 116
KR - Corea 110
CI - Costa d'Avorio 104
CH - Svizzera 71
ZA - Sudafrica 53
FI - Finlandia 52
JP - Giappone 50
BG - Bulgaria 49
JO - Giordania 49
EE - Estonia 40
NG - Nigeria 35
ES - Italia 31
CA - Canada 30
BE - Belgio 29
AR - Argentina 27
AT - Austria 27
ID - Indonesia 25
TR - Turchia 20
IR - Iran 17
PL - Polonia 15
MX - Messico 14
BD - Bangladesh 9
GR - Grecia 9
EC - Ecuador 8
AE - Emirati Arabi Uniti 7
HR - Croazia 7
MY - Malesia 7
PE - Perù 6
CL - Cile 5
PK - Pakistan 5
AU - Australia 4
DK - Danimarca 4
MA - Marocco 4
PH - Filippine 4
RO - Romania 4
CO - Colombia 3
CZ - Repubblica Ceca 3
LB - Libano 3
PY - Paraguay 3
TH - Thailandia 3
VE - Venezuela 3
IL - Israele 2
NO - Norvegia 2
NP - Nepal 2
PT - Portogallo 2
SA - Arabia Saudita 2
AL - Albania 1
AM - Armenia 1
AO - Angola 1
AZ - Azerbaigian 1
BH - Bahrain 1
DZ - Algeria 1
GT - Guatemala 1
HN - Honduras 1
IQ - Iraq 1
IS - Islanda 1
KZ - Kazakistan 1
LK - Sri Lanka 1
MZ - Mozambico 1
RE - Reunion 1
SK - Slovacchia (Repubblica Slovacca) 1
SM - San Marino 1
SY - Repubblica araba siriana 1
TN - Tunisia 1
TT - Trinidad e Tobago 1
UY - Uruguay 1
Totale 13.416
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Città #
Singapore 877
Chandler 543
Bologna 541
Ashburn 533
Southend 504
Fairfield 503
Hefei 308
Hong Kong 298
Santa Clara 292
Houston 252
Wilmington 234
Woodbridge 227
Seattle 215
Ann Arbor 210
Cambridge 188
Beijing 163
Ho Chi Minh City 155
Dong Ket 144
Dublin 143
Princeton 137
Lomé 134
Hanoi 120
Dallas 110
Seoul 109
Boardman 108
Abidjan 104
Jacksonville 71
Turin 71
Bern 65
Milan 64
Frankfurt am Main 61
Nanjing 59
Padova 55
Westminster 55
Bristol 54
Los Angeles 53
Falls Church 50
Amman 49
Berlin 49
Sofia 49
Redmond 47
New York 43
Tokyo 43
Buffalo 40
Helsinki 40
San Diego 36
Trento 36
Marano 34
Bengaluru 33
Munich 32
Abeokuta 31
Islington 29
Rome 29
Brussels 28
Shenyang 28
Changsha 26
Amsterdam 24
Argelato 23
Jinan 23
Saint Petersburg 23
Redondo Beach 22
Tianjin 20
Mülheim 17
Vienna 17
Bonn 15
Dearborn 15
Falkenstein 15
Guangzhou 15
Hebei 15
Jakarta 15
Jerez De La Frontera 15
Nanchang 15
Redwood City 15
Toronto 15
Bolzano 14
Bremen 14
Castel Maggiore 14
Pune 14
Chicago 13
Shanghai 13
Des Moines 12
Florence 12
São Paulo 12
Forlì 11
London 11
Mahé 11
Medford 11
Paris 11
Rimini 11
Wuhan 11
Zhengzhou 11
Da Nang 10
Phoenix 10
Ravenna 10
Taizhou 10
Verona 10
Biên Hòa 9
Hyderabad 9
Hải Dương 9
Modena 9
Totale 9.123
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Nome #
Inhibition of microglia over-activation restores neuronal survival and maturation in a mouse model of CDKL5 deficiency disorder 351
CDKL5 protein substitution therapy rescues neurological phenotypes of a mouse model of CDKL5 disorder 293
Age-related cognitive and motor decline in a mouse model of CDKL5 deficiency disorder is associated with increased neuronal senescence and death 289
Characterization of Perinatal Stem Cell Spheroids for the Development of Cell Therapy Strategy 288
Beneficial Antioxidant Effects of Coenzyme Q10 in In Vitro and In Vivo Models of CDKL5 Deficiency Disorder 257
Cardiac Functional and Structural Abnormalities in a Mouse Model of CDKL5 Deficiency Disorder 247
First in Class Dual Non-ATP-Competitive Glycogen Synthase Kinase 3β/Histone Deacetylase Inhibitors as a Potential Therapeutic to Treat Alzheimer’s Disease 234
Luteolin Treatment Ameliorates Brain Development and Behavioral Performance in a Mouse Model of CDKL5 Deficiency Disorder 226
A GABAB receptor antagonist rescues functional and structural impairments in the perirhinal cortex of a mouse model of CDKL5 deficiency disorder 226
CDKL5 deficiency entails sleep apneas in mice 224
CDKL5 deficiency predisposes neurons to cell death through the deregulation of SMAD3 signaling (vol 29, pg 658, 2019) 224
Expression of a Secretable, Cell-Penetrating CDKL5 Protein Enhances the Efficacy of Gene Therapy for CDKL5 Deficiency Disorder 220
Functional impairments in the perirhinal cortex of a mouse model of CDKL5 deficiency disorder are ameliorated by a GABAB receptor antagonist 220
Dietary restriction differentially protects from neurodegeneration in animal models of excitotoxicity. 212
Artificial protein and its applications 208
Heterozygous CDKL5 Knockout Female Mice Are a Valuable Animal Model for CDKL5 Disorder 208
HDAC4: a key factor underlying brain developmental alterations in CDKL5 disorder 201
Age-related impairment of olfactory bulb neurogenesis in the Ts65Dn mouse model of Down syndrome 195
Inhibition of microglia overactivation restores neuronal survival in a mouse model of CDKL5 deficiency disorder 195
CDKL5, a novel MYCN-repressed gene, blocks cell cycle and promotes differentiation of neuronal cells 189
Cyclic AMP-mediated regulation of transcription factor Lot1 expression in cerebellar granule cells. 187
Lithium Restores Age Related Olfactory Impairment in the Ts65Dn Mouse Model of Down Syndrome 187
The amyloid precursor protein (APP) triplicated gene impairs neuronal precursor differentiation and neurite development through two different domains in the Ts65Dn mouse model for down syndrome. 186
Inhibition of GSK3β rescues hippocampal development and learning in a mouse model of CDKL5 disorder 186
Postnatal neurogenesis in the dentate gyrus of the guinea pig 184
APP-dependent alteration of GSK3β activity impairs neurogenesis in the Ts65Dn mouse model of Down syndrome. 183
Neurochemical correlates of nicotine neurotoxicity on rat habenulo-interpeduncular cholinergic neurons. 181
Early Pharmacotherapy with Fluoxetine Rescues Dendritic Pathology in the Ts65Dn Mouse Model of Down Syndrome 180
Treatment with FRAX486 rescues neurobehavioral and metabolic alterations in a female mouse model of CDKL5 deficiency disorder 179
Epigallocatechin gallate: A useful therapy for cognitive disability in Down syndrome? 177
Functional and structural impairments in the perirhinal cortex of a mouse model of CDKL5 deficiency disorder are rescued by a TrkB agonist 176
Treatment with the GSK3-beta inhibitor Tideglusib improves hippocampal development and memory performance in juvenile, but not adult, Cdkl5 knockout mice 175
APP-dependent up-regulation of Ptch1 underlies proliferation impairment of neural precursors in Down syndrome. 174
Increased DNA Damage and Apoptosis in CDKL5-Deficient Neurons 172
Widespread impairment of cell proliferation in the neonate Ts65Dn mouse, a model for Down syndrome. 171
Pharmacotherapy with sertraline rescues brain development and behavior in a mouse model of CDKL5 deficiency disorder 170
Cell cycle alteration and decreased cell proliferation in the hippocampal dentate gyrus and in the neocortical germinal matrix of fetuses with Down syndrome and in Ts65Dn mice 169
Long-term effect of neonatal inhibition of APP gamma-secretase on hippocampal development in the Ts65Dn mouse model of Down syndrome 169
Choline acetyltransferase activity at different ages in brain of Ts65Dn mice, an animal model for Down's syndrome and related neurodegenerative diseases. 168
Sex differences in the stereological parameters of the hippocampal dentate gyrus of the guinea pig before puberty 167
Cell cycle elongation impairs proliferation of cerebellar granule cell precursors in the Ts65Dn Mouse, an animal model for Down syndrome. 166
Early Pharmacotherapy Restores Neurogenesis and Cognitive Performance in the Ts65Dn Mouse Model for Down Syndrome 163
Treatment with a GSK-3β/HDAC Dual Inhibitor Restores Neuronal Survival and Maturation in an In Vitro and In Vivo Model of CDKL5 Deficiency Disorder 163
Inhibition of APP gamma-secretase restores Sonic Hedgehog signaling and neurogenesis in the Ts65Dn mouse model of Down syndrome 160
Loss of CDKL5 impairs survival and dendritic growth of newborn neurons by altering AKT/GSK-3β signaling. 152
Early-onset brain alterations during postnatal development in a mouse model of CDKL5 deficiency disorder 152
AR-A014418-based dual Glycogen Synthase Kinase 3β/Histone Deacetylase inhibitors as potential therapeutics for Alzheimer's disease 151
Nitric oxide negatively regulates proliferation and promotes neuronal differentiation through N-Myc downregulation. 150
Proliferation of cerebellar precursor cells is negatively regulated by nitric oxide in newborn rat. 149
Impact of environmental enrichment on neurogenesis in the dentate gyrus during the early postnatal period. 148
Effect of early isolation on signal transfer in the entorhinal cortex-dentate-hippocampal system 146
CB1 cannabinoid receptors increase neuronal precursor proliferation through AKT/GSK-3{beta}/{beta}-catenin signaling 145
Sex differences in the hilar mossy cells of the guinea-pig before puberty. 143
Early-occurring proliferation defects in peripheral tissues of the Ts65Dn mouse model of Down syndrome are associated with patched1 over expression 143
Mapping pathological phenotypes in a mouse model of CDKL5 disorder. 143
Pharmacotherapy with Fluoxetine Restores Functional Connectivity from the Dentate Gyrus to Field CA3 in the Ts65Dn Mouse Model of Down Syndrome 139
Widespread proliferation impairment and hypocellularity in the cerebellum of fetuses with Down syndrome. 136
Lot1 is a key element of the pituitary adenylate cyclase-activating polypeptide (PACAP)/cyclic AMP pathway that negatively regulates neuronal precursor proliferation. 136
Timing of therapies for downsyndrome: The sooner, the better 136
The place of choline acetyltransferase activity measurement in the "cholinergic hypothesis" of neurodegenerative diseases 134
null 130
Prenatal pharmacotherapy rescues brain development in a Down's syndrome mouse model. 129
The green tea polyphenol epigallocatechin-3-gallate (EGCG) restores CDKL5-dependent synaptic defects in vitro and in vivo 129
Is it possible to improve neurodevelopmental abnormalities in Down syndrome? 128
Voluntary Running Improves Behavioral and Structural Abnormalities in a Mouse Model of CDKL5 Deficiency Disorder 127
Updating the dual role of brain nitric oxide in neurodegeneration/neuroprotection: understanding molecular mechanisms to devise drug approaches. 124
Short- and long-term effects of neonatal pharmacotherapy with epigallocatechin-3-gallate on hippocampal development in the Ts65Dn mouse model of Down syndrome 116
Neonatal isolation impairs neurogenesis in the dentate gyrus of the guinea pig. 116
Characterisation of sleep apneas and respiratory circuitry in mice lacking CDKL5 112
Role of nitric oxide in the regulation of neuronal proliferation, survival and differentiation. 111
Neurogenesis impairment and increased cell death reduce total neuron number in the hippocampal region of fetuses with Down syndrome 108
Site-specific abnormalities in the visual system of a mouse model of CDKL5 deficiency disorder 106
null 100
TATK-CDKL5 FUSION PROTEINS, COMPOSITIONS, FORMULATIONS, AND USE THEREOF 98
null 97
Lithium restores neurogenesis in the subventricular zone of the Ts65Dn mouse, a model for Down sindrome 89
Effects of a ciliary neurotrophic factor (CNTF) small-molecule peptide mimetic in an in vitro and in vivo model of CDKL5 deficiency disorder 86
Long-term effects of neonatal treatment with fluoxetine on cognitive performance in Ts65Dn mice. 76
Heterozygous CDKL5 Knockout Female Mice Are a Valuable Animal Model for CDKL5 Disorder 71
Sex differences in the hippocampal dentate gyrus of the guinea-pig before puberty 62
Autistic-relevant behavioral phenotypes of a mouse model of cyclin-dependent kinase-like 5 deficiency disorder 52
Therapeutic efficacy of the BKCa channel opener chlorzoxazone in a mouse model of Fragile X syndrome 49
Design, synthesis and pharmacological evaluation of multitarget GPR40 agonists/HDAC6 inhibitors for Alzheimer's disease 42
Adult-Onset Deletion of CDKL5 in Forebrain Glutamatergic Neurons Impairs Synaptic Integrity and Behavior in Mice 36
Sex differences in the hilar mossy cells of the guinea-pig before puberty 36
Effects of gestational or neonatal treatment with alpha-difluoromethylornithine on ornithine decarboxylase and polyamines in developing rat brain and on adult rat neurochemistry 36
Nitric oxide regulates cGMP-dependent cAMP-responsive element binding protein phosphorylation and Bcl-2 expression in cerebellar neurons: Implication for a survival role of nitric oxide 28
Lactic acid bacteria as microbial cell factories for the in vivo delivery of therapeutic proteins as secretable TAT fusion products 28
Safety and efficacy of Igk-TATk-CDKL5 gene therapy in mosaic CDKL5 deficiency 21
Totale 13.646
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Categoria #
all - tutte 35.484
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 35.484
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021754 0 0 0 0 0 96 12 63 90 98 53 342
2021/20221.475 99 71 117 117 135 102 62 80 71 107 261 253
2022/20232.213 173 366 105 260 162 196 55 125 365 51 166 189
2023/2024797 58 83 37 85 49 135 88 70 50 40 42 60
2024/20252.529 139 289 183 211 397 161 154 95 90 228 142 440
2025/20263.067 502 840 526 475 689 35 0 0 0 0 0 0
Totale 13.646