CRIS Current Research Information System

CIANI, ELISABETTA
 Distribuzione geografica
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Continente #
NA - Nord America 4.367
EU - Europa 3.150
AS - Asia 1.446
AF - Africa 271
SA - Sud America 13
OC - Oceania 4
Totale 9.251
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Nazione #
US - Stati Uniti d'America 4.352
IT - Italia 1.127
GB - Regno Unito 652
CN - Cina 509
SG - Singapore 410
DE - Germania 376
SE - Svezia 281
VN - Vietnam 241
IN - India 151
TG - Togo 134
IE - Irlanda 118
UA - Ucraina 112
FR - Francia 98
RU - Federazione Russa 81
CH - Svizzera 70
BG - Bulgaria 49
JO - Giordania 47
ZA - Sudafrica 47
CI - Costa d'Avorio 43
EE - Estonia 40
NG - Nigeria 32
FI - Finlandia 29
BE - Belgio 28
NL - Olanda 24
ES - Italia 23
CA - Canada 15
ID - Indonesia 14
IR - Iran 13
JP - Giappone 13
TR - Turchia 13
SC - Seychelles 12
AT - Austria 10
GR - Grecia 9
HK - Hong Kong 9
HR - Croazia 7
AE - Emirati Arabi Uniti 6
BR - Brasile 6
PL - Polonia 5
AU - Australia 4
DK - Danimarca 4
PK - Pakistan 4
LB - Libano 3
PE - Perù 3
RO - Romania 3
AR - Argentina 2
CL - Cile 2
IL - Israele 2
MA - Marocco 2
MY - Malesia 2
NO - Norvegia 2
PH - Filippine 2
SA - Arabia Saudita 2
TH - Thailandia 2
BD - Bangladesh 1
KR - Corea 1
LK - Sri Lanka 1
SK - Slovacchia (Repubblica Slovacca) 1
SM - San Marino 1
TN - Tunisia 1
Totale 9.251
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Città #
Chandler 543
Southend 504
Fairfield 503
Bologna 437
Singapore 378
Ashburn 312
Santa Clara 282
Houston 251
Wilmington 234
Woodbridge 227
Seattle 213
Ann Arbor 210
Cambridge 188
Dong Ket 144
Princeton 137
Lomé 134
Dublin 118
Boardman 106
Jacksonville 71
Bern 65
Turin 65
Nanjing 59
Westminster 55
Bristol 54
Padova 54
Falls Church 50
Berlin 49
Sofia 49
Amman 47
Redmond 47
Abidjan 43
Milan 43
Beijing 41
Frankfurt am Main 37
San Diego 36
Trento 36
Marano 34
Abeokuta 31
Islington 29
New York 28
Shenyang 28
Brussels 27
Helsinki 27
Changsha 24
Argelato 23
Jinan 23
Saint Petersburg 23
Mülheim 17
Rome 17
Dearborn 15
Hebei 15
Jerez De La Frontera 15
Nanchang 15
Redwood City 15
Pune 14
Bolzano 13
Bremen 13
Guangzhou 13
Jakarta 13
Tianjin 13
Des Moines 12
Mahé 11
Paris 11
Toronto 11
Amsterdam 10
Florence 10
Forlì 10
Medford 10
Shanghai 10
Taizhou 10
Modena 9
Norwalk 9
Phoenix 9
Wuhan 9
Zhengzhou 9
Haikou 8
Los Angeles 8
Ravenna 8
Taiyuan 8
Verona 8
Bari 7
Hangzhou 7
Hyderabad 7
Istanbul 7
Ningbo 7
Piacenza 7
Shenzhen 7
Tokyo 7
Ardabil 6
Boydton 6
Lanzhou 6
Monmouth Junction 6
Naples 6
Olalla 6
San Francisco 6
Vienna 6
Cesena 5
Chicago 5
Chongqing 5
Ferrara 5
Totale 6.621
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Nome #
CDKL5 protein substitution therapy rescues neurological phenotypes of a mouse model of CDKL5 disorder 241
Inhibition of microglia over-activation restores neuronal survival and maturation in a mouse model of CDKL5 deficiency disorder 213
CDKL5 deficiency entails sleep apneas in mice 196
CDKL5 deficiency predisposes neurons to cell death through the deregulation of SMAD3 signaling (vol 29, pg 658, 2019) 192
Characterization of Perinatal Stem Cell Spheroids for the Development of Cell Therapy Strategy 185
Functional impairments in the perirhinal cortex of a mouse model of CDKL5 deficiency disorder are ameliorated by a GABAB receptor antagonist 176
Age-related impairment of olfactory bulb neurogenesis in the Ts65Dn mouse model of Down syndrome 174
Heterozygous CDKL5 Knockout Female Mice Are a Valuable Animal Model for CDKL5 Disorder 171
HDAC4: a key factor underlying brain developmental alterations in CDKL5 disorder 170
A GABAB receptor antagonist rescues functional and structural impairments in the perirhinal cortex of a mouse model of CDKL5 deficiency disorder 165
Dietary restriction differentially protects from neurodegeneration in animal models of excitotoxicity. 158
Age-related cognitive and motor decline in a mouse model of CDKL5 deficiency disorder is associated with increased neuronal senescence and death 158
The amyloid precursor protein (APP) triplicated gene impairs neuronal precursor differentiation and neurite development through two different domains in the Ts65Dn mouse model for down syndrome. 157
CDKL5, a novel MYCN-repressed gene, blocks cell cycle and promotes differentiation of neuronal cells 156
APP-dependent alteration of GSK3β activity impairs neurogenesis in the Ts65Dn mouse model of Down syndrome. 156
Inhibition of GSK3β rescues hippocampal development and learning in a mouse model of CDKL5 disorder 154
Early Pharmacotherapy with Fluoxetine Rescues Dendritic Pathology in the Ts65Dn Mouse Model of Down Syndrome 151
Widespread impairment of cell proliferation in the neonate Ts65Dn mouse, a model for Down syndrome. 146
Treatment with the GSK3-beta inhibitor Tideglusib improves hippocampal development and memory performance in juvenile, but not adult, Cdkl5 knockout mice 145
Lithium Restores Age Related Olfactory Impairment in the Ts65Dn Mouse Model of Down Syndrome 144
Cell cycle alteration and decreased cell proliferation in the hippocampal dentate gyrus and in the neocortical germinal matrix of fetuses with Down syndrome and in Ts65Dn mice 143
APP-dependent up-regulation of Ptch1 underlies proliferation impairment of neural precursors in Down syndrome. 143
Neurochemical correlates of nicotine neurotoxicity on rat habenulo-interpeduncular cholinergic neurons. 142
Choline acetyltransferase activity at different ages in brain of Ts65Dn mice, an animal model for Down's syndrome and related neurodegenerative diseases. 141
Cell cycle elongation impairs proliferation of cerebellar granule cell precursors in the Ts65Dn Mouse, an animal model for Down syndrome. 141
Cyclic AMP-mediated regulation of transcription factor Lot1 expression in cerebellar granule cells. 137
Long-term effect of neonatal inhibition of APP gamma-secretase on hippocampal development in the Ts65Dn mouse model of Down syndrome 137
Postnatal neurogenesis in the dentate gyrus of the guinea pig 136
Epigallocatechin gallate: A useful therapy for cognitive disability in Down syndrome? 132
null 130
Inhibition of APP gamma-secretase restores Sonic Hedgehog signaling and neurogenesis in the Ts65Dn mouse model of Down syndrome 129
Functional and structural impairments in the perirhinal cortex of a mouse model of CDKL5 deficiency disorder are rescued by a TrkB agonist 129
Early Pharmacotherapy Restores Neurogenesis and Cognitive Performance in the Ts65Dn Mouse Model for Down Syndrome 128
Sex differences in the stereological parameters of the hippocampal dentate gyrus of the guinea pig before puberty 126
Early-occurring proliferation defects in peripheral tissues of the Ts65Dn mouse model of Down syndrome are associated with patched1 over expression 122
Mapping pathological phenotypes in a mouse model of CDKL5 disorder. 122
Impact of environmental enrichment on neurogenesis in the dentate gyrus during the early postnatal period. 122
Effect of early isolation on signal transfer in the entorhinal cortex-dentate-hippocampal system 121
CB1 cannabinoid receptors increase neuronal precursor proliferation through AKT/GSK-3{beta}/{beta}-catenin signaling 121
Increased DNA Damage and Apoptosis in CDKL5-Deficient Neurons 121
Inhibition of microglia overactivation restores neuronal survival in a mouse model of CDKL5 deficiency disorder 121
Luteolin Treatment Ameliorates Brain Development and Behavioral Performance in a Mouse Model of CDKL5 Deficiency Disorder 120
Loss of CDKL5 impairs survival and dendritic growth of newborn neurons by altering AKT/GSK-3β signaling. 120
Pharmacotherapy with sertraline rescues brain development and behavior in a mouse model of CDKL5 deficiency disorder 119
Proliferation of cerebellar precursor cells is negatively regulated by nitric oxide in newborn rat. 118
Timing of therapies for downsyndrome: The sooner, the better 118
Treatment with a GSK-3β/HDAC Dual Inhibitor Restores Neuronal Survival and Maturation in an In Vitro and In Vivo Model of CDKL5 Deficiency Disorder 117
Cardiac Functional and Structural Abnormalities in a Mouse Model of CDKL5 Deficiency Disorder 116
Widespread proliferation impairment and hypocellularity in the cerebellum of fetuses with Down syndrome. 113
The place of choline acetyltransferase activity measurement in the "cholinergic hypothesis" of neurodegenerative diseases 113
Pharmacotherapy with Fluoxetine Restores Functional Connectivity from the Dentate Gyrus to Field CA3 in the Ts65Dn Mouse Model of Down Syndrome 112
Nitric oxide negatively regulates proliferation and promotes neuronal differentiation through N-Myc downregulation. 111
Sex differences in the hilar mossy cells of the guinea-pig before puberty. 108
Expression of a Secretable, Cell-Penetrating CDKL5 Protein Enhances the Efficacy of Gene Therapy for CDKL5 Deficiency Disorder 107
Is it possible to improve neurodevelopmental abnormalities in Down syndrome? 106
Lot1 is a key element of the pituitary adenylate cyclase-activating polypeptide (PACAP)/cyclic AMP pathway that negatively regulates neuronal precursor proliferation. 104
Prenatal pharmacotherapy rescues brain development in a Down's syndrome mouse model. 102
Updating the dual role of brain nitric oxide in neurodegeneration/neuroprotection: understanding molecular mechanisms to devise drug approaches. 101
null 100
The green tea polyphenol epigallocatechin-3-gallate (EGCG) restores CDKL5-dependent synaptic defects in vitro and in vivo 99
Role of nitric oxide in the regulation of neuronal proliferation, survival and differentiation. 98
null 97
Neurogenesis impairment and increased cell death reduce total neuron number in the hippocampal region of fetuses with Down syndrome 88
Neonatal isolation impairs neurogenesis in the dentate gyrus of the guinea pig. 88
TATK-CDKL5 FUSION PROTEINS, COMPOSITIONS, FORMULATIONS, AND USE THEREOF 87
Artificial protein and its applications 80
Site-specific abnormalities in the visual system of a mouse model of CDKL5 deficiency disorder 78
Treatment with FRAX486 rescues neurobehavioral and metabolic alterations in a female mouse model of CDKL5 deficiency disorder 74
Early-onset brain alterations during postnatal development in a mouse model of CDKL5 deficiency disorder 72
Short- and long-term effects of neonatal pharmacotherapy with epigallocatechin-3-gallate on hippocampal development in the Ts65Dn mouse model of Down syndrome 63
Lithium restores neurogenesis in the subventricular zone of the Ts65Dn mouse, a model for Down sindrome 55
First in Class Dual Non-ATP-Competitive Glycogen Synthase Kinase 3β/Histone Deacetylase Inhibitors as a Potential Therapeutic to Treat Alzheimer’s Disease 54
Long-term effects of neonatal treatment with fluoxetine on cognitive performance in Ts65Dn mice. 54
Voluntary Running Improves Behavioral and Structural Abnormalities in a Mouse Model of CDKL5 Deficiency Disorder 36
Sex differences in the hippocampal dentate gyrus of the guinea-pig before puberty 33
Heterozygous CDKL5 Knockout Female Mice Are a Valuable Animal Model for CDKL5 Disorder 31
Effects of gestational or neonatal treatment with alpha-difluoromethylornithine on ornithine decarboxylase and polyamines in developing rat brain and on adult rat neurochemistry 23
Therapeutic efficacy of the BKCa channel opener chlorzoxazone in a mouse model of Fragile X syndrome 17
Sex differences in the hilar mossy cells of the guinea-pig before puberty 14
Nitric oxide regulates cGMP-dependent cAMP-responsive element binding protein phosphorylation and Bcl-2 expression in cerebellar neurons: Implication for a survival role of nitric oxide 14
Characterisation of sleep apneas and respiratory circuitry in mice lacking CDKL5 14
Autistic-relevant behavioral phenotypes of a mouse model of cyclin-dependent kinase-like 5 deficiency disorder 11
Totale 9.437
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Categoria #
all - tutte 24.151
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 24.151
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201.081 0 0 0 0 0 0 228 259 282 121 94 97
2020/20211.139 178 91 36 50 30 96 12 63 90 98 53 342
2021/20221.475 99 71 117 117 135 102 62 80 71 107 261 253
2022/20232.213 173 366 105 260 162 196 55 125 365 51 166 189
2023/2024797 58 83 37 85 49 135 88 70 50 40 42 60
2024/20251.387 139 289 183 211 397 161 7 0 0 0 0 0
Totale 9.437