We identified, combining different approaches (sequencing, literature mining, and in silico porcine expressed sequence tag mining), a few hundreds of single nucleotide polymorphisms (SNPs; n. = 667) in candidate genes for fat deposition traits and genotyped these markers in Italian Large White pigs using a selective genotyping approach based on estimated breeding value for back fat thickness. Significant association (P nominal value <0.10) was obtained for 65 SNPs. This large scale genotyping of SNPs in candidate genes for fat deposition traits provided DNA markers that could be applied in selection programs in the Italian Large White pig breed.
Fontanesi L., Scotti E., Galimberti G., Calò D.G., Fronza R., Colombo M., et al. (2010). Selective Genotyping Analysis of 677 SNPs to Identify Markers Associated with Back Fat Thickness in Italian Large White Pigs. s.l : s.n.
Selective Genotyping Analysis of 677 SNPs to Identify Markers Associated with Back Fat Thickness in Italian Large White Pigs
FONTANESI, LUCA;SCOTTI, EMILIO;GALIMBERTI, GIULIANO;CALO', DANIELA GIOVANNA;FRONZA, RAFFAELE;COLOMBO, MICHELA;MARTELLI, PIER LUIGI;CASADIO, RITA;RUSSO, VINCENZO
2010
Abstract
We identified, combining different approaches (sequencing, literature mining, and in silico porcine expressed sequence tag mining), a few hundreds of single nucleotide polymorphisms (SNPs; n. = 667) in candidate genes for fat deposition traits and genotyped these markers in Italian Large White pigs using a selective genotyping approach based on estimated breeding value for back fat thickness. Significant association (P nominal value <0.10) was obtained for 65 SNPs. This large scale genotyping of SNPs in candidate genes for fat deposition traits provided DNA markers that could be applied in selection programs in the Italian Large White pig breed.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
