This is a case of [(68) Ga]Ga-Prostate-specific membrane antigen (PSMA)-11 PET/CT in a 73-years old patient presenting high Prostate Specific Antigen (PSA) levels despite both multi-parametric magnetic resonance imaging (mpMRI) and 12-core saturation biopsy negative for prostate cancer (Pca). This is a highly interesting case because, despite the advanced metastatic spread at initial presentation as showed by [Ga-68]Ga-PSMA-PET/CT, the primary Pca was detected by none of the diagnostic techniques (12 random sample biopsy, mpMRI, PSMA PET/CT). However, [Ga-68]Ga-PSMA-PET/CT showed a suspicious axillary lesion suitable for biopsy, which finally resulted as Pca metastasis. This case report is therefore a brilliant example of how [Ga-68]Ga-PSMA-PET/CT optimized patient's management.
Case report: PSMA PET/CT addresses the correct diagnosis in a patient with metastatic prostate cancer despite negative core biopsies and mpMRI. A diagnostic challenge / Vetrone, Luigia; Cuzzani, Giulia; Mei, Riccardo; Zanoni, Lucia; Bertaccini, Alessandro; Bianchi, Lorenzo; Castellucci, Paolo; Gaudiano, Caterina; Cappelli, Alberta; Giunchi, Francesca; Fanti, Stefano. - In: FRONTIERS IN ONCOLOGY. - ISSN 2234-943X. - STAMPA. - 13:(2023), pp. 1101221.1-1101221.5. [10.3389/fonc.2023.1101221]
Case report: PSMA PET/CT addresses the correct diagnosis in a patient with metastatic prostate cancer despite negative core biopsies and mpMRI. A diagnostic challenge
Zanoni, Lucia;Bertaccini, Alessandro;Bianchi, Lorenzo;Fanti, Stefano
2023
Abstract
This is a case of [(68) Ga]Ga-Prostate-specific membrane antigen (PSMA)-11 PET/CT in a 73-years old patient presenting high Prostate Specific Antigen (PSA) levels despite both multi-parametric magnetic resonance imaging (mpMRI) and 12-core saturation biopsy negative for prostate cancer (Pca). This is a highly interesting case because, despite the advanced metastatic spread at initial presentation as showed by [Ga-68]Ga-PSMA-PET/CT, the primary Pca was detected by none of the diagnostic techniques (12 random sample biopsy, mpMRI, PSMA PET/CT). However, [Ga-68]Ga-PSMA-PET/CT showed a suspicious axillary lesion suitable for biopsy, which finally resulted as Pca metastasis. This case report is therefore a brilliant example of how [Ga-68]Ga-PSMA-PET/CT optimized patient's management.File | Dimensione | Formato | |
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