This is a case of [68 Ga]Ga-Prostate-specific membrane antigen (PSMA)-11 PET/CT in a 73-years old patient presenting high Prostate Specific Antigen (PSA) levels despite both multi-parametric magnetic resonance imaging (mpMRI) and 12-core saturation biopsy negative for prostate cancer (Pca). This is a highly interesting case because, despite the advanced metastatic spread at initial presentation as showed by [68Ga]Ga-PSMA-PET/CT, the primary Pca was detected by none of the diagnostic techniques (12 random sample biopsy, mpMRI, PSMA PET/CT). However, [68Ga]Ga-PSMA-PET/CT showed a suspicious axillary lesion suitable for biopsy, which finally resulted as Pca metastasis. This case report is therefore a brilliant example of how [68Ga]Ga-PSMA-PET/CT optimized patient’s management.

Vetrone L., Cuzzani G., Mei R., Zanoni L., Bertaccini A., Bianchi L., et al. (2023). Case report: PSMA PET/CT addresses the correct diagnosis in a patient with metastatic prostate cancer despite negative core biopsies and mpMRI. A diagnostic challenge. FRONTIERS IN ONCOLOGY, 13, 1-5 [10.3389/fonc.2023.1101221].

Case report: PSMA PET/CT addresses the correct diagnosis in a patient with metastatic prostate cancer despite negative core biopsies and mpMRI. A diagnostic challenge

Vetrone L.;Cuzzani G.;Mei R.;Zanoni L.;Bertaccini A.;Bianchi L.;Castellucci P.;Giunchi F.;Fanti S.
2023

Abstract

This is a case of [68 Ga]Ga-Prostate-specific membrane antigen (PSMA)-11 PET/CT in a 73-years old patient presenting high Prostate Specific Antigen (PSA) levels despite both multi-parametric magnetic resonance imaging (mpMRI) and 12-core saturation biopsy negative for prostate cancer (Pca). This is a highly interesting case because, despite the advanced metastatic spread at initial presentation as showed by [68Ga]Ga-PSMA-PET/CT, the primary Pca was detected by none of the diagnostic techniques (12 random sample biopsy, mpMRI, PSMA PET/CT). However, [68Ga]Ga-PSMA-PET/CT showed a suspicious axillary lesion suitable for biopsy, which finally resulted as Pca metastasis. This case report is therefore a brilliant example of how [68Ga]Ga-PSMA-PET/CT optimized patient’s management.
2023
Vetrone L., Cuzzani G., Mei R., Zanoni L., Bertaccini A., Bianchi L., et al. (2023). Case report: PSMA PET/CT addresses the correct diagnosis in a patient with metastatic prostate cancer despite negative core biopsies and mpMRI. A diagnostic challenge. FRONTIERS IN ONCOLOGY, 13, 1-5 [10.3389/fonc.2023.1101221].
Vetrone L.; Cuzzani G.; Mei R.; Zanoni L.; Bertaccini A.; Bianchi L.; Castellucci P.; Gaudiano C.; Cappelli A.; Giunchi F.; Fanti S.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/957753
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