In the domestic rabbit (Oryctolagus cuniculus), classical genetic studies have identified five alleles at the Extension locus: E D (dominant black), E S (steel, weaker version of E D ), E (wild type, normal extension of black), e J (Japanese brindling, mosaic distribution of black and yellow) and e (non-extension of black, yellow/red with white belly). Sequencing almost the complete coding sequence (CDS) of the rabbit MC1R gene, we recently identified two in-frame deletions associated with dominant black (c.280_285del6; alleles E D or E S ) and recessive red (c.304_333del30; allele e) coat colours. It remained to characterize the e J allele whose phenotypic effect is similar to the Orange and Sex-linked yellow loci of cat and Syrian hamster.

Fontanesi L., Scotti E., Colombo M., Beretti F., Forestier L., Dall'Olio S., et al. (2010). A composite six bp in-frame deletion in the melanocortin 1 receptor (MC1R) gene is associated with the Japanese brindling coat colour in rabbits (Oryctolagus cuniculus). BMC GENETICS, 11, 1-11 [10.1186/1471-2156-11-59].

A composite six bp in-frame deletion in the melanocortin 1 receptor (MC1R) gene is associated with the Japanese brindling coat colour in rabbits (Oryctolagus cuniculus)

FONTANESI, LUCA;SCOTTI, EMILIO;COLOMBO, MICHELA;BERETTI, FRANCESCA;DALL'OLIO, STEFANIA;RUSSO, VINCENZO;
2010

Abstract

In the domestic rabbit (Oryctolagus cuniculus), classical genetic studies have identified five alleles at the Extension locus: E D (dominant black), E S (steel, weaker version of E D ), E (wild type, normal extension of black), e J (Japanese brindling, mosaic distribution of black and yellow) and e (non-extension of black, yellow/red with white belly). Sequencing almost the complete coding sequence (CDS) of the rabbit MC1R gene, we recently identified two in-frame deletions associated with dominant black (c.280_285del6; alleles E D or E S ) and recessive red (c.304_333del30; allele e) coat colours. It remained to characterize the e J allele whose phenotypic effect is similar to the Orange and Sex-linked yellow loci of cat and Syrian hamster.
2010
Fontanesi L., Scotti E., Colombo M., Beretti F., Forestier L., Dall'Olio S., et al. (2010). A composite six bp in-frame deletion in the melanocortin 1 receptor (MC1R) gene is associated with the Japanese brindling coat colour in rabbits (Oryctolagus cuniculus). BMC GENETICS, 11, 1-11 [10.1186/1471-2156-11-59].
Fontanesi L.; Scotti E.; Colombo M.; Beretti F.; Forestier L.; Dall'Olio S.; Deretz S.; Russo V.; Allain D.; Oulmouden A.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/91666
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