Transmembrane proteins constitute some 20%–30% of proteins of all prokaryotic and eukaryotic organisms and are involved in fundamental biological processes. Experimental determination of their structure is difficult due to their peculiar property of being stable in a complex environment consisting of separate hydrophilic and hydrophobic phases. Computational tools are then necessary to fill the gap between the knowledge of protein sequence and the characterization of its role in the context of biological complexity.
Pier Luigi Martelli, C.S. (2018). Transmembrane Domain Prediction. Oxford : Academic Press [https://doi.org/10.1016/B978-0-12-809633-8.20269-0].
Transmembrane Domain Prediction
Pier Luigi Martelli;Castrense Savojardo;Giuseppe Profiti;Rita Casadio
2018
Abstract
Transmembrane proteins constitute some 20%–30% of proteins of all prokaryotic and eukaryotic organisms and are involved in fundamental biological processes. Experimental determination of their structure is difficult due to their peculiar property of being stable in a complex environment consisting of separate hydrophilic and hydrophobic phases. Computational tools are then necessary to fill the gap between the knowledge of protein sequence and the characterization of its role in the context of biological complexity.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
