CRIS Current Research Information System

The Interpreters' Newsletter

The Derivation and External Validation of a Fibrosis Risk Model for Colorectal Tumours Undergoing Endoscopic Submucosal Dissection

Background: Endoscopic submucosal dissection (ESD) is an advanced technique that can become more challenging in the presence of submucosal fibrosis. Predicting the grade of fibrosis is important in order to identify technically difficult ESD. Aims and Methods: Our study aimed to derive and validate a prediction model to determine the preoperative degree of submucosal fibrosis in colorectal tumours undergoing ESD. A predictive model was developed to derive the probability of an increasing subm...

Identification of Novel Potential Predisposing Variants in Familial Acute Myeloid Leukemia

BackgroundMyeloid neoplasms, including acute myeloid leukemia, have been traditionally among the less investigated cancer types concerning germline predisposition. Indeed, myeloid neoplasms with germline predisposition are challenging to identify because often display similar clinical and morphological characteristics of sporadic cases and have similar age at diagnosis. However, a misidentifications of familiarity in myeloid neoplasms have a critical impact on clinical management both for the...

Normative Considerations on Impact Assessments in EU Digital Policy

This paper assesses the increased normative role of impact assessments in the EU digital governance. :e frst investigate how impact assessments have gained prominence as regulatory tools in regulating the digital dimension. Then, we analyse, also from a comparative perspective, three different impact assessment models enshrined in EU legal acts (i.e., the GDPR, the AI Act and the DSA). Finally, we highlight six shortcomings common to the previously addressed models.