OBJECTIVES: Although the etiology of liver disease affects the features of hepatocellular carcinoma (HCC) diagnosed during surveillance, it is not known whether it influences patients' survival. We analyzed the impact of etiology on the characteristics and outcome of HCC detected during surveillance. METHODS: In this cohort study, 742 patients with HCC detected during semiannual or annual surveillance were selected from the ITA.LI.CA database, including 1,834 consecutive patients observed in three primary and seven tertiary care settings for HCC. Patients were grouped according to etiology: hepatitis B virus (HBV, 87), hepatitis C virus (HCV, 461), alcohol (59), and multietiology (135). RESULTS: In all etiologic groups, most HCCs were unifocal (51-68%) and most of them were

Impact of etiology of cirrhosis on the survival of patients diagnosed with hepatocellular carcinoma during surveillance.

Franco Trevisani;Giulia Magini;Valentina Santi;Antonio Maria Morselli-Labate;Maria Chiara Cantarini;Marco Zoli;Mauro Bernardi;Pietro Andreone
Membro del Collaboration Group
;
Maurizio Biselli
Membro del Collaboration Group
;
Paolo Caraceni
Membro del Collaboration Group
;
Carmela Cursaro
Membro del Collaboration Group
;
Marco Domenicali
Membro del Collaboration Group
;
Annagiulia Gramenzi
Membro del Collaboration Group
;
LI BASSI, SILVIA
Membro del Collaboration Group
;
Donatella Magalotti
Membro del Collaboration Group
;
Federica Mirici Cappa
Membro del Collaboration Group
;
Andrea Zambruni
Membro del Collaboration Group
;
Gian Luca Grazi
Membro del Collaboration Group
;
Bruno Nardo
Membro del Collaboration Group
;
Matteo Ravaioli
Membro del Collaboration Group
;
Cristina Rossi
Membro del Collaboration Group
;
Rita Golfieri
Membro del Collaboration Group
2007

Abstract

OBJECTIVES: Although the etiology of liver disease affects the features of hepatocellular carcinoma (HCC) diagnosed during surveillance, it is not known whether it influences patients' survival. We analyzed the impact of etiology on the characteristics and outcome of HCC detected during surveillance. METHODS: In this cohort study, 742 patients with HCC detected during semiannual or annual surveillance were selected from the ITA.LI.CA database, including 1,834 consecutive patients observed in three primary and seven tertiary care settings for HCC. Patients were grouped according to etiology: hepatitis B virus (HBV, 87), hepatitis C virus (HCV, 461), alcohol (59), and multietiology (135). RESULTS: In all etiologic groups, most HCCs were unifocal (51-68%) and most of them were
Franco Trevisani; Giulia Magini; Valentina Santi; Antonio Maria Morselli-Labate; Maria Chiara Cantarini; Maria Anna Di Nolfo; Paolo Del Poggio; Luisa Benvegnù; Gianludovico Rapaccini; Fabio Farinati; Marco Zoli; Franco Borzio; Edoardo Giovanni Giannini; Eugenio Caturelli; Mauro Bernardi; for the Italian Liver Cancer (ITA.LI.CA) Group; Pietro Andreone; Maurizio Biselli; Paolo Caraceni; Maria Chiara Cantarini; Carmela Cursaro; Marco Domenicali; Annagiulia Gramenzi; Silvia Li Bassi; Donatella Magalotti; Federica Mirici Cappa; Andrea Zambruni; Gian Luca Grazi; Bruno Nardo; Matteo Ravaioli; Cristina Rossi; Rita Golfieri
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/128357
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