To contribute to the application of the Childhood Atopic Dermatitis Impact Scale (CADIS), 135 Italian parents of children with Atopic Dermatitis (AD) aged birth to 6 years completed: CADIS, Infants Dermatitis Quality of Life Index (IDQOL) or Children’s Dermatology Life Quality Index (CDLQI), and Dermatitis Family Impact questionnaire (DFI). A sub-sample of 66 caregivers completed the CADIS again, 48 hours later. Disease severity was measured with the SCORAD index. Exploratory factor analyses (EFA) almost replicated the general factor structure of the original CADIS, established on a U.S. sample. However, some differences emerged, probably due to cultural differences. A reduced version of the original CADIS was also obtained, based on the EFA, to facilitate use in clinical settings. The original and the shorter versions were tested for reliability: overall Cronbach’s alphas and test-retest reliability for the child- and parent-related scales were acceptable. Regarding concurrent validity, estimates showed the CADIS to adequately correlate with SCORAD, IDQOL-CDLQI and DFI. Multiple comparison tests for discriminant validity revealed significant differences between extreme groups based on AD severity for all 5 domains of CADIS. The original CADIS showed adequate validity and reliability in Italy as well, and the shorter version showed promising psychometric properties.

Italian Validation of the Childhood Atopic Dermatitis Impact Scale: A Contribution to Its Clinical Application

NERI, ERICA;AGOSTINI, FRANCESCA;GREMIGNI, PAOLA;GOBBI, FRANCESCA;CASU, GIULIA;MONTI, FIORELLA
2012

Abstract

To contribute to the application of the Childhood Atopic Dermatitis Impact Scale (CADIS), 135 Italian parents of children with Atopic Dermatitis (AD) aged birth to 6 years completed: CADIS, Infants Dermatitis Quality of Life Index (IDQOL) or Children’s Dermatology Life Quality Index (CDLQI), and Dermatitis Family Impact questionnaire (DFI). A sub-sample of 66 caregivers completed the CADIS again, 48 hours later. Disease severity was measured with the SCORAD index. Exploratory factor analyses (EFA) almost replicated the general factor structure of the original CADIS, established on a U.S. sample. However, some differences emerged, probably due to cultural differences. A reduced version of the original CADIS was also obtained, based on the EFA, to facilitate use in clinical settings. The original and the shorter versions were tested for reliability: overall Cronbach’s alphas and test-retest reliability for the child- and parent-related scales were acceptable. Regarding concurrent validity, estimates showed the CADIS to adequately correlate with SCORAD, IDQOL-CDLQI and DFI. Multiple comparison tests for discriminant validity revealed significant differences between extreme groups based on AD severity for all 5 domains of CADIS. The original CADIS showed adequate validity and reliability in Italy as well, and the shorter version showed promising psychometric properties.
2012
Neri E.; Agostini F.; Gremigni P.; Gobbi F.; Casu G.; Chamlin S.L.; Monti F.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/119129
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