A linkage and association analysis was made on 14 Italian families with recurrent migraine. We analyzed five chromosomal regions surrounding the candidate genes 5HT1D (lp36.3-34.3), 5HT1B (6q13), 5HT2A (13q14-21), 5HT transporter (17q11.2-12), CACNLB1 (17q11.2-22) and FHM (19p13), using 29 DNA polymorphic markers. All two-point lod scores were negative, and the χ2 sib-pair analyses were not significant, thus indicating the probable exclusion of these regions as sites of migraine genes in our population.

Monari, L., Mochi, M., Valentino, M.L., Arnaldi, C., Cortelli, P., De Monte, A., et al. (1997). Searching for migraine genes: Exclusion of 290 cM out of the whole human genome. ITALIAN JOURNAL OF NEUROLOGICAL SCIENCES, 18(5), 277-282 [10.1007/bf02083304].

Searching for migraine genes: Exclusion of 290 cM out of the whole human genome

Valentino M. L.;Cortelli P.;Pierangeli G.;
1997

Abstract

A linkage and association analysis was made on 14 Italian families with recurrent migraine. We analyzed five chromosomal regions surrounding the candidate genes 5HT1D (lp36.3-34.3), 5HT1B (6q13), 5HT2A (13q14-21), 5HT transporter (17q11.2-12), CACNLB1 (17q11.2-22) and FHM (19p13), using 29 DNA polymorphic markers. All two-point lod scores were negative, and the χ2 sib-pair analyses were not significant, thus indicating the probable exclusion of these regions as sites of migraine genes in our population.
1997
Monari, L., Mochi, M., Valentino, M.L., Arnaldi, C., Cortelli, P., De Monte, A., et al. (1997). Searching for migraine genes: Exclusion of 290 cM out of the whole human genome. ITALIAN JOURNAL OF NEUROLOGICAL SCIENCES, 18(5), 277-282 [10.1007/bf02083304].
Monari, L.; Mochi, M.; Valentino, M. L.; Arnaldi, C.; Cortelli, P.; De Monte, A.; Pierangeli, G.; Prologo, G.; Scapoli, C.; Soriani, S.; Montagna, P....espandi
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11585/1011311
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